Gene 94208.m00083 (T.vaginalis)

94208.m00083

Species: T.vaginalis
Alias: TvagK0239, 94208.m00083
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
94208.m00083.AA Protein None 364 None Fasta, JSON
94208.m00083.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of 94208.m00083.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 94208.m00083.AA S_TKc 20-272 29 3.3e-73 250.45 SMART 1-231 (231) Show / Hide 
Range on Protein: 20-272
Range on HMM: 1-231/231
Sequence Identity: 29% (80 aa)

YKFTQMIGKGGFAEVFLVEHIKFLTLFVAKVMTVDASEVQSTWEIFDSETKALSTLNHPHIIRLYDHFQIGCQFYYILEYCPN--GSLFDEIEVTRG---
|.. . ||||.|..|... |.|   ..  |..           | . .| . |.  .||.|..|||.||    .| ..|||..  |.||| |.  ..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LPIPRFLTLASQIVSALAYCHANGIAHRDIKPGNILLDENKRAKLTDFGLCMQTKIGELHKTFSGSCEFTAPEIFLRKPNDPFKGDVWALGIVFAIL
   .|  .   .. ||..||.||| .|| |||.|| ||||||  . |..||||. |       .|| |. .. |||..   . ...| |.|..|......
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

ITGTSPWKCDSLGALRQLALAGNYKLNEFVPKEIADVIARMIVVDPDKRITMAELAE-------MPLF
..|  |.    . .. .. .          ..|  | | .. ..||.||.|  |. .       .| |
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 94208.m00083.AA CAMKL 20-272 29 3.2e-70 223.27 In-house 1-297 (297) Show / Hide 
Range on Protein: 20-272
Range on HMM: 1-297/297
Sequence Identity: 29% (88 aa)

YKFTQMIGKGGFAEVFLVEHIKF-LTLFVAKVMTVDASEVQSTWEIFDS------------ETKALSTLN---HPHIIRLYDHFQIGCQ------FYYIL
|.. . .|||.|..| | .||..  .    |..  .        .  .             | . .. ||   ||.||.||....          .| ..
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCPNGS--LFDEI--EVTRG--LPIPRFLTLASQIVSALAYCHANGIAHRDIKPGNILLDENK--RAKLTDFGLCMQTK-I----GELHKTFSGSCEFT
|||..|.  ||| |  .  |.  .| .    .  |||||..||| .||.|||||| |||||||.   .|..|||.. . . .    |.. ||| || .. 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEIFLR--KPNDPFKGDVWALGIVFAILITGTSPWKCDS---------LGALRQLALAGNYKLNEFVPKEIADVIARMIVVDPDKRITMAELAEMPLF
|||||..  || | .| |.|..|..   ...|. |...|.         .  ...  . ...    .|. .  | | .| .|.|.||.|. .. . | .
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 94208.m00083.AA CAMK 25-272 19 6.3e-70 224.27 In-house 1-425 (425) Show / Hide 
Range on Protein: 25-272
Range on HMM: 1-425/425
Sequence Identity: 19% (82 aa)

MIGKGGFAEVFLVEHIKFL------------TLFVAKVMT-----------------VDASEVQS--------TWEIFDSETKALST-------LNHPHI
 .|.|.|..|.|..|..              . . .|..                  .| |....        . . . .| . ...       |.||.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRLYDHFQ------------IGCQ--------FYYIL---EYCPNG----SLFDEIEVT---------------RGLPIPRFLTLASQIVSALAYCHANG
|.||....               .        .| ..   |||..|     ||| |                  . ..     ..  ||.||..||| ..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IAHRDIKPGNILLDENK-----------------RAKLTDFGLCMQTKI------------------------GELHKTFSGSCEFTA-PEIFLR-----
|.|||.|| |||||.|.                   |..|||.  . .                         |.. ||| |. |. | ||....     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------KPNDPFKGDVWALGIVFAILITGTSPWKCD-------------SLGALRQLALAGNYK-LNEFVPK-----------------------EIA
        || ...| |.|..|..  |. .|..|.  |             ..  | .  ..|.|    .....                       |  
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DVIARMIVVDPDKRITMAELAEMPLF
| | .| .|||.||.| ..  . | .
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 94208.m00083.AA MARK 72-272 36 3e-60 195.7 In-house 53-262 (262) Show / Hide 
Range on Protein: 72-272
Range on HMM: 53-262/262
Sequence Identity: 36% (77 aa)

LSTLNHPHIIRLYDHFQ--IGCQ-FYYILEYCPNGSLFDEIEVT--RGLPIPRFLTLASQIVSALAYCHANGIAHRDIKPGNILLDENK--RAKLTDFGL
.. |.||.||.|.. ..     . .| |.||...|.|.| |.    . |. .   .. .|||||. ||| ..|.|||||| |||.|||.   .|..|||.
MKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGF

CMQTKIGELHKTFSGSCEFTAPEIFLRKPNDPFKGDVWALGIVFAILITGTSPWKCDS--LGALRQLALAGNYKLNEFVPKEIADVIARMIVVDPDKRIT
. . . |.. .|| |. .. ||||||.|| | .| |.|.||.|  ....|. |.. |.  .  |..  |.|.|.   .|.||. . | |...|.|..|.|
SICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPT

MAELAEMPLF
. |. . | .
IEEIMKHPWM
Kinase 94208.m00083.AA Pkinase 20-272 25 4.4e-60 210.71 Pfam 1-293 (293) Show / Hide 
Range on Protein: 20-272
Range on HMM: 1-293/293
Sequence Identity: 25% (76 aa)

YKFTQMIGKGGFAEVFLVEHIKFLTLFVAKVMTVDASEVQSTWEIFDS--ETKALSTLNHPHIIRLYDHFQIGCQFYYILEYCPNG----SLFDEIE--V
|.. . ||.|.|..|..  |..   ... |.. .. .|  . ...     | . .  ||||.|.|||| |. .   | ..|||..|    .||| |.   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

TRGL--PIPRFLTLASQIVSALAYCHANGIAHRDIKPGNILLDENKRA----KLTDFGLCMQ--TKIGELHKTFSGSCEFTAPEIFLR-KPNDPFKGDVW
 ...  .       . ||...|.|||..|| |||.|| |||.|.|       |..||||. |  .  ..  .|| |. .. |||. .|  . .. | |.|
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEV-IRGGQYYGPKVDMW

ALGIVFAILITGTSPWKCD------SLGALRQLALAGNYKLNEFVP---------------------KEIADVIARMIVVDPDKRITMAELAEMPLF
..|........|  |.. .      .  .. .. . . .. ... .                     .|  |.| ... .|| ||.| ... . | |
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 94208.m00083.AA Ciliate-E2 20-272 21 6.4e-58 197.41 In-house 1-365 (365) Show / Hide 
Range on Protein: 20-272
Range on HMM: 1-365/365
Sequence Identity: 21% (80 aa)

YKFTQMIGKGGFAEVFLVEH--------IKFLTLFV---------AKVMTVDASEVQST-WEIFDSETKAL----------------STLNHPHIIRLYD
||| ..||.|.|. |.....        ||. . .          .|.. .    ..    |.. .| . .                ..||||.||..|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

HFQ--IGCQFYYILEYCPNGSLFDEIEVTRGLP-----------IPRFLTLASQIVS---------------ALAYCHANG-IAHRDIKPGNILLDENKR
.||      .|...|||  |.||| |.  .              .   ...  ||..               || |.| .. | |||||| |||.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

AKLTDFGLCMQTKIG--------------------------------ELHKTFSGSCEFTAPEIFLRKPNDP--------FKGDVWALGIVFAILITGTS
 |..||||. . ..                                 ....|. |. .. ||||. .|..|         .| |.|.||... ....|  
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PWKCDSLGALRQLALAGNYKLNEF------------------VPKEIADVIAR----MIVVDPDKRIT-MAELAEMPLF
|.         |  . ........                  ...|  | | .    |...||.|||| . .. . | |
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 94208.m00083.AA AGC 20-272 21 2.3e-57 145.83 In-house 1-395 (395) Show / Hide 
Range on Protein: 20-272
Range on HMM: 1-395/395
Sequence Identity: 21% (87 aa)

YKFTQMIGKGGFAEVFLVEHI------KFLTLFVAKVMTVDA-SEVQS--TWEIFDSE------------TKALSTLN----------HPHIIR-LYDHF
..|  .||||.| .|.||..           ..  ||.  .         . |   .|             . |...|          || |.. |.  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QIGCQ--FYYILEYCP---------NG-SLFDEIEV--TRG-LPIPRFLTLASQ-------IVSALAYCHA-NGIAHRD-IKPGNILLDENKRAKLTDFG
|       | ..||.|          |  ||  .     .| .. .|    |..       ||.|| | |  .|| ||| .|| ||||||.   ||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LCMQTKIGE---------------------------------------------------LHKTFSG--SCEFTAPEIFLRKPNDPFKGDVWA--LGIVF
|| . . ..                                                   . .|| |  . |. ||||.       .  | |.  ||...
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCLM

AILITGTSPWKCDSLG----------ALRQLALAG------NYKLN----------EFVPKEIADVIARMIVVDPDKRIT----------MAELAEMPLF
  ..|| .|   |. .           . |. . |      . |..          ... .|  | | .....||.||..            |. . | |
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 94208.m00083.AA ULK 20-272 23 1.7e-52 180.76 In-house 1-329 (329) Show / Hide 
Range on Protein: 20-272
Range on HMM: 1-329/329
Sequence Identity: 23% (77 aa)

YKFTQMIGKGGFAEVFLVEHIKF----LTLFVAKVMT---VDASEVQST----WEIFDSETKALSTLN--------HPHIIRLYDHFQIG--CQFYYILE
|   ...||| |. |.  ...|       ....|..     . .. ...    |. ...| | . .|.        ||.|..||| |.    . .| |.|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCPNGSLFDEIEVTRGLPIPR----------FLTLASQIVSALAYCHANGIAHRDIKPGNILLDENK------------RAKLTDFGLCMQTKIG----E
||. | |.. |.  ..|| .            .    ||.... . | ..| |||||| |||.....            ..|..|||.. .   .    .
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

LHKTFS------GSCEFTAPEIFL----RKPNDPFKGDVWALGIVFAILITGTSP---WKCDSLGALRQLALAGN----------YKLN-------EFVP
. .|..      |.  . ||.|.     .|| . .| |.| ||..|  ...|  |   |   ..  . .  |  |           .|.         . 
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

KEIADVIARMIVVDPDKRITMAELAEMPLF
.|. | | ||...|...||.  || ..|.|
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 94208.m00083.AA Ciliate-E2-Unclassified 20-272 20 9.6e-52 177.75 In-house 1-352 (352) Show / Hide 
Range on Protein: 20-272
Range on HMM: 1-352/352
Sequence Identity: 20% (74 aa)

YKFTQMIGKGGFAEVFLVEHIKFLTLF-----VAKVMTVDASEVQSTWEIFDSETKALSTLN-------------------HPHIIRLYDHFQIGCQFYY
||. . ||.|||..|....|.|   ..       |.. ..   ...   ..  | |..  ..                   ||.|......||    .| 
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

ILEYCPNGSLFDEIEVTRG-----------------LPIPRFL-----TLASQIVSALAYCHANG-IAHRDIKPGNILLDENK---RAKLTDFGLCMQTK
..|||..|.|.. |.   .                 ..    .     ... ||...| |.| .. | |||||| |||.|.|.   . |..|||.... .
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

----------------IGELHKTFSGSCEFT----APEIFLRKPNDP---FKGDVWALGIVFAILITGTSPWKCDSLGA----------------LRQLA
                . .. .||.|. ..     |||.. .. .|    .| |.|.||...  ...|. | .. .                   |.|  
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

LAGNYKLNE--------FVPKEIADVIA----RMIVVDPDKRITMAELAEMPLF
...|.. ..         ...| .| |     .|....|.||||. .. . |.|
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 94208.m00083.AA ULK 20-272 22 8.3e-50 171.78 In-house 1-324 (324) Show / Hide 
Range on Protein: 20-272
Range on HMM: 1-324/324
Sequence Identity: 22% (75 aa)

YKFTQMIGKGGFA-EVFLVEHIKF---LTLFVAKVMT---VDASEVQST----WEIFDSETKALSTLN---HPH--IIRLYDHFQIG--CQFYYILEYCP
|   ...||| |.  |.  ...|      .. .|..       .. ...    |. ...| . . .|.   ||.  |..||| |.      .| |.|||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGSLFDEIEVTRGLPIPR----------FLTLASQIVSALAYCHANGIAHRDIKPGNILLDENK------------RAKLTDFGLCMQTKIG----ELHK
 | |.. |.  ..||              .    ||.... . | ..| |||||| |||. ...            ..|..|||.. .   .     . .
GGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

TFS------GSCEFTAPEIFL----RKPNDPFKGDVWALGIVFAILITGTSP---WKCDSLGALRQLALAGN---------YKLNEFVP--------KEI
|.       |.  . ||.|.     .|| . .| |.| ||..|  ...|  |   |   ..    .  |  |         ..  .| .        .|.
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPEC

ADVIARMIVVDPDKRITMAELAEMPLF
 | | ||...|...||.  |. ..|.|
KDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 94208.m00083.AA MELK 20-272 35 9e-50 168.13 In-house 1-254 (254) Show / Hide 
Range on Protein: 20-272
Range on HMM: 1-254/254
Sequence Identity: 35% (90 aa)

YKFTQMIGKGGFAEVFLVEHIKFLTLFVAKVMTVDASEVQSTWEIFDSETKALSTLNHPHIIRLYDHFQIGCQFYYILEYCPNGSLFDEIEVTRGLPIPR
|.  . || |||| | |  ||  ||     .  .|  .. .       |  ||  | | || .||   .   ... ..|||| | .|| |     |    
YEVHDEIGTGGFAKVKLACHI--LTNQMVAIKIMDKNQLGHDLPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEE

FLTLASQIVSALAYCHANGIAHRDIKPGNILLDENKRAKLTDFGLCMQTK-IGELH--KTFSGSCEFTAPEIFLRKPNDPFKGDVWALGIVFAILITGTS
   .  |||||.|| |. | ||||.|| |.|.||... || ||||| .||   . |  .|  ||  . |||.   |       |||..||.  .|. |  
TRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFL

PWKCDSLGALRQLALAGNYKLNEFVPKEIADVIARMIVVDPDKRITMAELAEMPLF
|.  | . .. .  . | |.  ...  |  ... .|. |||.||| | .| . |  
PFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase 94208.m00083.AA QIK 68-272 33 9.4e-47 161.64 In-house 48-272 (272) Show / Hide 
Range on Protein: 68-272
Range on HMM: 48-272/272
Sequence Identity: 33% (76 aa)

ETKALSTLNHPHIIRLYDHFQIGCQFYYILEYCPNGSLFDEIEVTRGL-------------------PIPRFLTLA--SQIVSALAYCHANGIAHRDIKP
| . .  |.|||||.||.        | . |||.|| .|| . .  |.                   |..   .    .||.|| .|||  .|.|||.| 
EVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYL-CKHGRKGVKMVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKA

GNILLDENKRAKLTDFGLCMQTKIGELHKTFSGSCEFTAPEIFLRKPNDPFKGDVWALGIVFAILITGTSPWKCDSLGALRQLALAGNYKLNEFVPKEIA
 |||||.|   |. |||.    | |.| .|. ||  . |||.|. |  |  | |.| .|.|  .|..|  |   ..|  |||  | | ...  |.... .
ENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCE

DVIARMIVVDPDKRITMAELAEMPLF
. | .| ||||..|.|..   . .  
HLIRHMLVVDPEHRYTIMQICQHRWM
Kinase 94208.m00083.AA TyrKc 20-272 22 5.2e-15 19.97 SMART 1-280 (280) Show / Hide 
Range on Protein: 20-272
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

YKFTQMIGKGGFAEVFLVEHIKFLTLFVA-KVMTVDASEVQSTWEIFDSETKALSTL--NHPHIIRLYDHFQIG-------CQFYYILEYCPNGSLFDEI
 .. ...| | | ||.. . .    . || |..  ||       | | .| . .. |  .||.|.|||     .        . . ..||.|.|.| | .
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

EVTRG-LPIPRFLTLASQIVSALAYCHANGIAHRDIKPGNILLDENKRAKLTDFGLCMQTKIG------ELHKTFSG--SCEF------TAPEIFLRKPN
  .|. |. . .|  . || .  .| | ... |||.   |.|..||...| .||||.   . .      .  .. ..  .. .      .||| .     
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-----

DPFKG------DVWALGIV-FAILITGTSPWKC-----DSLGALRQLALAGNYKLNEFV---------PKEIADVIARMIVVDPDKRITMAELAEMPLF
  ..|      |||. |.. . |.  | .|.        |   ....  .|..               |.|. ... .    ||..| |..|.    .|
--NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 94208.m00083.AA Pkinase_Tyr 67-165 31 9.2e-09 30.3 Pfam 52-158 (270) Show / Hide 
Range on Protein: 67-165
Range on HMM: 52-158/270
Sequence Identity: 31% (34 aa)

SETKALSTL-NHPHIIRLYDHFQ-IGCQ--FYYILEYCPNGSLFDEIEV----TRGLPIPRFLTLASQIVSALAYCHANGIAHRDIKPGNILLDENKRAK
.| | ...| .||.|.|||      | .   | ..||.|.|.| |         . |.... |  . || ....| ..... |||.   |.|..||. .|
REAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVK

LTDFGLC
 .||||.
ICDFGLA
Kinase 94208.m00083.AA MARK 20-41 40 1.1e-05 14.8 In-house 1-22 (262) Show / Hide 
Range on Protein: 20-41
Range on HMM: 1-22/262
Sequence Identity: 40% (9 aa)

YKFTQMIGKGGFAEVFLVEHIK
||. . ||.|..|.| |. |..
YKMLKTIGHGSYAKVKLACHKH
Kinase 94208.m00083.AA QIK 20-40 47 0.309719 1.09 In-house 1-21 (272) Show / Hide 
Range on Protein: 20-40
Range on HMM: 1-21/272
Sequence Identity: 47% (10 aa)

YKFTQMIGKGGFAEVFLVEHI
|   . |||| || | |  |.
YDIERTIGKGNFAVVKLARHR