Gene 94734.m00180 (T.vaginalis)

94734.m00180

Species: T.vaginalis
Alias: TvagK0117, 94734.m00180
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
94734.m00180.AA Protein None 311 None Fasta, JSON
94734.m00180.kin_dom Protein Kinase Domain None 258 None Fasta, JSON

Protein domain

Protein domains of 94734.m00180.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 94734.m00180.AA CAMK1 9-266 45 4.2e-123 359.71 In-house 1-276 (276) Show / Hide 
Range on Protein: 9-266
Range on HMM: 1-276/276
Sequence Identity: 45% (126 aa)

YKILKEIGQGGFSRVYLGESLK---DQKKVAIKVIS-KTNDLC-EM---KDIQKEIKIQKQF---ESPYIVTFYDMYETKKEIVIVMEYVNGGELFDHIV
|.. |||| | || |||..  .   ..|..|||.|. |..    .|   . ...|| | |..     | |. ||. ||..... .|||.|.|||||| ||
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

QKGSFTEQEAANIIQQVLIGLKVLHEKKVIHRDLKPENLLLFIDEKGNTTVK--IADFGLSGLIDNSED-MKRFCGTEGYAAPEIMKN---VPYDWSVDV
.||..||..|..|..|.|  .. .|.| . ||||||||| |. |.. . ..|  |||||||  .|. |. ||  ||| || |||. ..    ||| ..|.
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENL-LYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDM

WSLGVIVYNLVSGYKPFDSDD-DYELYEQVVAADYEFFSPEFDCISDE-CKDFITHMLQAKAKDRYTVEMLLEHPWI
|| ||| | |  || || ... | ||.|..  ..||| ||..| |||.  ||||.|||    | |||.|  |.||||
WSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase 94734.m00180.AA CAMK 14-266 25 6.30000000001e-114 368.64 In-house 1-425 (425) Show / Hide 
Range on Protein: 14-266
Range on HMM: 1-425/425
Sequence Identity: 25% (110 aa)

EIGQGGFSRVYLGESLKDQ------------KKVAIKVISKT---------------------------NDLCEMKDIQKEIKIQKQ-------FESPYI
..|.|.|. |.|..  ...            .|||||.|.|.                            . . .| ...||.| |.          | |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VTFYDMYET-------------------KKEIVIVM---EYVNGGEL----FDHIVQKGS---------------FTEQEAANIIQQVLIGLKVLHEKKV
. .|..||.                   .|....||   ||. ||||    ||.||..|.               |||.||. ...|.. ... .|....
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDLKPENLLLFIDEKGN-------------TTVKIADFGLSGLIDNSE------------------------DMKRFCGTEGYAA-PEIMKN------
.||||||||.||  .....              ..||.|||..  .| .|                         || |||| .|.| ||. .       
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------VPYDWSVDVWSLGVIVYNLVSGYKPFDSD-------------DDYELYEQVVAADYEFFSPEFDC------------ISDE--------CKD
         .|. ..|.||.||| | ...|| ||..|             .||||.|.. ...|.| .|.|.             ||||        |||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

FITHMLQAKAKDRYTVEMLLEHPWI
.| .|||   ..|.|.|  |.|||.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 94734.m00180.AA S_TKc 9-266 33 1.1e-101 345.06 SMART 1-231 (231) Show / Hide 
Range on Protein: 9-266
Range on HMM: 1-231/231
Sequence Identity: 33% (92 aa)

YKILKEIGQGGFSRVYLGESLKDQKKVAIKVISKTNDLCEMKDIQKEIKIQKQFESPYIVTFYDMYETKKEIVIVMEYVNG--GELFDHIVQKGS-----
|.||..||.|.|..||..   |....||||.|.        ..|..||.| |.   |.||..||.... ... .||||..|  |.|||.|...|.     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-FTEQEAANIIQQVLIGLKVLHEKKVIHRDLKPENLLLFIDEKGNTTVKIADFGLSGLIDNSEDMKRFCGTEGYAAPEIMKNVPYDW-SVDVWSLGVIVY
 |.| .|. ...|.. .|. .|....|||||||||.||        ..||.||||. ..      . ||||  | |||..   .|.  ..|.||.|.|.|
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

NLVSGYKPFDSDDDYELYEQVVAADYEFFSPEFDCISDECKDFITHMLQAKAKDRYTVEMLLE-------HPWI
 ...|| ||.  ..........              |.|.|||| ..||   ..|.|.  .|.       |||.
EMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 94734.m00180.AA Pkinase 9-266 35 1.6e-100 345.03 Pfam 1-293 (293) Show / Hide 
Range on Protein: 9-266
Range on HMM: 1-293/293
Sequence Identity: 35% (106 aa)

YKILKEIGQGGFSRVYLGESLKDQKKVAIKVISKTNDLCEMKDIQK---EIKIQKQFESPYIVTFYDMYETKKEIVIVMEYVNGG----ELFDHIV--QK
|.|.. ||.|.|..||..   ...|.||.|.|.| .. .... .     ||.| | . .|.||..||..|.|..| .||||..||    .|||.|   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GSF--TEQEAANIIQQVLIGLKVLHEKKVIHRDLKPENLLLFIDEKGNT--TVKIADFGLSGL--IDNSEDMKRFCGTEGYAAPEIMK-NVPYDWSVDVW
|.|  .|.|. ... |.| ||. .|....|||||||||.|  ||..|..  .|||.||||. .  . |.. |. |||| .|.|||. . . .|. .||.|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENIL--IDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SLGVIVYNLVSGYKPFDSD------DDYELYEQVVAADYEFFSPEFDCIS-----------------DECKDFITHMLQAKAKDRYTVEMLLEHPWI
|.|.|.| ...|. ||...      |........  ....| .|. ..||                 .||||||. .|. . |.|.| | .|.|||.
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 94734.m00180.AA CAMKL 9-266 33 4.2e-96 307.18 In-house 1-297 (297) Show / Hide 
Range on Protein: 9-266
Range on HMM: 1-297/297
Sequence Identity: 33% (103 aa)

YKILKEIGQGGFSRVYLGES-LKDQKKVAIKVIS--KTN-DLCEMKD-----------IQKEIKIQKQFE---SPYIVTFYDMYETKKE------IVIVM
|.|.|..|.|.|. | |..  .  ..|||||.|   |.. | . .|            |..||.|.|..     | |. .|...||..       |..||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYVNGGE--LFDHIVQK----GSFTEQEAANIIQQVLIGLKVLHEKKVIHRDLKPENLLLFIDEKGNTTVKIADFGLSGLIDN-----SEDMKRFCGTEG
||. |||  |||.||..    |...| ||  . .|.. ... .|.....|||.||||.||  . .   ..||.|||.| ....      . .| |||.  
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN--NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPP

YAAPEIMKN--VPYD-WSVDVWSLGVIVYNLVSGYKPFDSDDD--------YELYEQVVAADYEFFSPEFDCISDECKDFITHMLQAKAKDRYTVEMLLE
|.|||| .    |||   ||.||.||| |..| || ||| |..        |.. .. .   |.   | .  .| .|.|.| .||| . ..|.|.. ...
YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYP---PIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMN

HPWI
||| 
HPWM
Kinase 94734.m00180.AA MARK 9-266 39 7.6e-92 300.49 In-house 1-262 (262) Show / Hide 
Range on Protein: 9-266
Range on HMM: 1-262/262
Sequence Identity: 39% (107 aa)

YKILKEIGQGGFSRVYLGESLKDQKKVAIKVISK--TNDLCEMKDIQKEIKIQKQFESPYIVTFYDMYE--TKKE-IVIVMEYVNGGELFDHIVQK--GS
||.||.||.|... |.|. ... ..|||||.. |   || ..|| .. ||.| |. . |.|. .... |  |..  |...|||. ||||.|.|...  | 
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

FTEQEAANIIQQVLIGLKVLHEKKVIHRDLKPENLLLFIDEKGNTTVKIADFGLSGLIDNSEDMKRFCGTEGYAAPEIMKNVPYD-WSVDVWSLGVIVYN
 .| ||  | .|.. ... .|.| ..|||.||||.|  |||.||  .||.|||.|  | . .  ..||||  |.||||..  |||   ||.|||||. | 
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENIL--IDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYF

LVSGYKPFDSDD--DYELYEQVVAADYEFFSPEFDCISDECKDFITHMLQAKAKDRYTVEMLLEHPWI
.|.|| ||| |.  . |||..... .|....     .|.||...|  .|..  ..| |.| ...|||.
MVCGYFPFDGDTQDYKELYKKILRGKYDIPCH----VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 94734.m00180.AA Ciliate-E2a 9-266 38 1.8e-89 263.53 In-house 1-275 (275) Show / Hide 
Range on Protein: 9-266
Range on HMM: 1-275/275
Sequence Identity: 38% (105 aa)

YKILKEIGQGGFSRVYLGESLKDQKKVAIKVISKTNDLCE--MKDIQKEIKIQKQFESPYIVTFYDMYETKKEIVIVMEYVNGGELFDHIVQKGSFTEQ-
||..|.||.| | .||| . ... |. |.|...| .   .   . ...||.| .|   | |  .|. ||... . .||||..||||.| |.|...|.|  
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEI

-EAANIIQQVL-IGLKVLHEKKVIHRDLKPENLLLF-IDEKG--NTTVKIADFGLSGLIDNSED--MKRFCGTEGYAAPEIMKNVP------YDWSVDVW
 |.. |.|| |  ||  .| ....||||||||.|.  .. ..  |. .||.||||.  ||  |   |.  ||| || |||. .|        || ..|.|
QEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDMW

SLGVIVYNLVSGYKPFDSDDDYELYEQVVAADYEFFSPE-FDCISDECKDFITHMLQAKAKDRYTVEMLLEHPWI
|.||| | |..|. ||.  .  |  .|. .  . | .|| . ..|.||||..  ||.   | |.| . .|.||| 
SCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 94734.m00180.AA Ciliate-E2 9-266 27 1.2e-86 294.11 In-house 1-365 (365) Show / Hide 
Range on Protein: 9-266
Range on HMM: 1-365/365
Sequence Identity: 27% (106 aa)

YKILKEIGQGGFSRVYLGESLKDQKKVAIKVISKTN----------D------LCEMKD----IQKEIKIQKQFE----------------SPYIVTFYD
||..| ||||.|. ||...  |.||..|||.|  ..          .       . .|.    | .||.| .. .                .|.|. .|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

MYE--TKKEIVIVMEYVNGGELFDHIVQK-----------GSFTEQEAANIIQQVL---------------IGLKVLHEKK-VIHRDLKPENLLLFIDEK
 ..  ... | .||||..||.|||.| ..           ..|||.|...|..|.|                .|. ||.|. .||||.||||.|.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

GNTTVKIADFGLSGLIDNSEDMKR--------------------------------FCGTEGYAAPEIMKNVP---------YDWSVDVWSLGVIVYNLV
    .||.|||||  .|.......                                .||| || |||| .. .         || ..|.|||||| | ..
----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEML

SGYKPFDSDDDYELYEQVVAADYEFFSPE--------------FDCISDECKDFITH----MLQAKAKDRYT-VEMLLEHPWI
.|. ||        ..|    ...|..||              .. .|.||||.|      ||| . . |.|  | .|.|||.
FGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 94734.m00180.AA DCAMKL 9-266 36 2.2e-85 265.52 In-house 1-279 (279) Show / Hide 
Range on Protein: 9-266
Range on HMM: 1-279/279
Sequence Identity: 36% (102 aa)

YKILKEIGQGGFSRVYLGESLKDQ-KKVAIKV-----------------ISKTNDLCEMKDIQKEIKIQKQFESPYIVTFYDMYETKKEIVIVMEYVNGG
|.| . || | |. |..    ... .| | |.                 | | .     . |. |..| .. . |.|.  |. ..|.... .||||| ||
YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKCKGKEHMIDNEVSIMQKIKHPHIIQLYEHWDTETHYYLVMEYVQGG

ELFDHIVQKGSFTEQEAANIIQQVLIGLKVLHEKKVIHRDLKPENLLLFIDEKGNTTVKIADFGLSGLIDN-SEDMKRFCGTEGYAAPEIMKNVPYDWSV
 |||.|.. . ||| .|| .. ..   || |||. ..|||.||||||.  .| | ...| .||||   ..     . . |||  | ||||.. . |   |
DLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILMETGYGCKV

DVWSLGVIVYNLVSGYKPFDSD--DDYELYEQVVAADYEFFSPEFDCISDECKDFITHMLQAKAKDRYTVEMLLEHPWI
|.|..||| | |  |. || |   |  || .|......|| .|. | |||  || |.||||.  . ||| |  ..|||.
DIWAAGVILYILLCGFPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase 94734.m00180.AA ULK 9-266 30 3.3e-80 272.79 In-house 1-329 (329) Show / Hide 
Range on Protein: 9-266
Range on HMM: 1-329/329
Sequence Identity: 30% (102 aa)

YKILKEIGQGGFSRVYLGESLKD----QKKVAIKVIS---KTNDLCE------MKDIQKEIKIQKQFE----SPY----IVTFYDMYETKKE--IVIVME
| . ...|.| | .|| |.  |.    ..|||.|.|.   . ... |      .. ...||||.|.      ...    || .||..||...  | |.||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YVNGGELFDHIVQKGS----------FTEQEAANIIQQVLIGLKVLHEKKVIHRDLKPENLLLFIDE---------KGNTTVKIADFGLSGLIDNS----
| ||| |.. | ...           ..|||| ....| | |.| ||....||||.||.| |.  .          . | ..||||||..  .||.    
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHP-NGVLKIADFGFAKHVDNDNMEQ

EDMKRFC------GTEGYAAPEIMK----NVPYDWS-VDVWSLGVIVYNLVSGYKPFDSDDDYELYEQVVAADYE----------FFSPEFDC------I
..|. .       ||  | ||.| .    . ||. . .|.||||.| | .. |. || .   ...|.| .   ..           . ..|.       |
QMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQI

SDECKDFITHMLQAKAKDRYTVEMLLEHPWI
|.||||.|  ||| . ||| . | |..|||.
SPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 94734.m00180.AA ULK 9-266 30 4.7e-80 272.28 In-house 1-324 (324) Show / Hide 
Range on Protein: 9-266
Range on HMM: 1-324/324
Sequence Identity: 30% (101 aa)

YKILKEIGQGGFS-RVYLGESLKD---QKKVAIKVIS-----KTNDLCE----MKDIQKEIKIQKQFE---SPY--IVTFYDMYETK--KEIVIVMEYVN
| . ...|.| |   || |.  |.   ...||.|.|.     | . . |    .. ...||.|.|..    .|.  || .||..||.  . | |.||| |
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGELFDHIVQKGS---------FTEQEAANIIQQVLIGLKVLHEKKVIHRDLKPENLLLFIDE---------KGNTTVKIADFGLSGLIDNSEDMKRFC-
|| |.. | ...          ..|||| ....| . |.| ||....||||.||.|.|.  .          . | ..||||||..  .|| .  .  | 
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHP-NGVLKIADFGFAKHVDNNNMEQQMCQ

---------GTEGYAAPEIMK----NVPYDWS-VDVWSLGVIVYNLVSGYKPFDSDDDYELYE------------QVVAADYEFFSP---EFDCISDECK
         ||  | ||.| .    . ||. . .|.||||.| | .. |. || |.  ...|.            |.   .  .  |   . . ||.|||
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECK

DFITHMLQAKAKDRYTVEMLLEHPWI
|.|  ||| . ||| . | ...|||.
DLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 94734.m00180.AA Ciliate-E2-Unclassified 9-266 29 1.9e-77 263.64 In-house 1-352 (352) Show / Hide 
Range on Protein: 9-266
Range on HMM: 1-352/352
Sequence Identity: 29% (103 aa)

YKILKEIGQGGFSRVYLGESLKDQKKV-----AIKVISKT-----NDLCEMKDIQKEIKIQK----------------QFESPYIVTFYDMYETKKEIVI
|||.| ||||||. ||. .  |.. ..     ..|....      |   |.. ..||....|                .. .|.|| .... ..|. | |
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VMEYVNGGELFDHIVQKGS-----------------FTEQEAA-----NIIQQVLIGLKVLHEKK-VIHRDLKPENLLLFIDEKGNTTVKIADFGLSGLI
||||..||.|...| ....                 ||||.|.     ... |.| ||. ||.|. .||||.||||.|.  . | |  .||.|||.|  .
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK-NYYIKIIDFGISKKY

DNSED----------------MKRFCGTEGYA----APEIMKNVPYD----WSVDVWSLGVIVYNLVSGYKPFDSDDDYE----------------LYEQ
.....                |. |||| .|     |||....  ||     ..|.|||||| | .. || ||.. ....                ||..
QQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQN

VVAADYEFFSPEF----DCISDECKDFIT----HMLQAKAKDRYTVEMLLEHPWI
  . ...|.. ..    . .|.|.||||.     ||. . . |.| | .|.|||.
IKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 94734.m00180.AA Pkinase_Tyr 9-156 30 3.5e-18 62.2 Pfam 1-158 (270) Show / Hide 
Range on Protein: 9-156
Range on HMM: 1-158/270
Sequence Identity: 30% (50 aa)

YKILKEIGQGGFSRVYLGESL----KDQKKVAIKVISKTNDLCE--MKDIQKEIKIQKQF-ESPYIVTFYDMYE-TKKE--IVIVMEYVNGGELFDHIVQ
 ...|..|.| | .||.|.      ... .||.|..  . .  .  ..|  .|.|| ||.   | || .|      ..   | |||||. .| | |.  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

----KGSFTEQEAANIIQQVLIGLKVLHEKKVIHRDLKPENLLLFIDEKGNTTVKIADFGLS
    |...| ..  .. .|.  |.  |..|. |||||   | |.      | .|||.||||.
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE----NNVVKICDFGLA
Kinase 94734.m00180.AA TyrKc 9-266 24 2.8e-17 56.65 SMART 1-280 (280) Show / Hide 
Range on Protein: 9-266
Range on HMM: 1-280/280
Sequence Identity: 24% (73 aa)

YKILKEIGQGGFSRVYLGESLKDQKKVAIKVISKTNDLCEMKDIQKEIKIQKQF--ESPYIVTFYDMYETK-------KEIVIVMEYVNGGELFDHIVQK
 . .|..| | | .||.|.      .||.|.. .      ..|. .|..| ...  . | || .|    ..       . . |||||. .| | |..  .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

GS-FTEQEAANIIQQVLIGLKVLHEKKVIHRDLKPENLLLFIDEKGNTTVKIADFGLSGLIDNS------EDMKRFC---GTEG-----YAAPEIMKNVP
.  .. ..  ..  |.  |   ||.|..|||||   | |.  .     ||||.|||||  |..       .|..|     |. .       ||| ..   
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YDWSVDVWSLGVIVYNLVS-GYKPFDS-----DDDYELYEQVVAADYEFFSPE-----FDCISDECKDFITHMLQAKAKDRYTVEMLLEHPWI
.    |||| ||  . . . | .|         ...|..|.| . ..    |.     | | .||  . ..   .....|| | . .  |  .
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF