Gene 85337.m00308 (T.vaginalis)

85337.m00308

Species: T.vaginalis
Alias: 85337.m00308, TvagK0046
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
85337.m00308.AA Protein None 375 None Fasta, JSON
85337.m00308.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of 85337.m00308.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 85337.m00308.AA CAMK 17-264 23 7.79999999999e-106 342.08 In-house 1-425 (425) Show / Hide 
Range on Protein: 17-264
Range on HMM: 1-425/425
Sequence Identity: 23% (101 aa)

VIGSGAFATVYKAYNPELR------------RLFAIKCFKKSNLKN-------------------------SKEEETFQREIDTMAY-------MDHPGL
..|.|.|..|..... .              . .|||  .|. ||.                          | .. ..|||. |         .||| .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLHNIFED-------------------ENNFYLVL---DYCAGGEL----FDYILKK---------------KRLDEHTAALVFKQIVSAISYCHSFGI
.||. ..||                   ....|.|.   .|| ||||    |||| ..               .|..|. |. .|.||.||. |||| .|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHRDLKPENILIDKFP-----------------KVMISDFGLCGYLKE------------------------STLMSTFVGSPIYTA-PECLQN------
.||||||||||.|.                   .. |.|||.  ....                          .|.||.|.| | | || |.       
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------QEYDGRLSDIWSLGVILFGMVTGEHPWKTN-------------NTAIMLKQIYNADFT-YPSYLSN-----------------------DVKE
       ..|.|. .|.||.||||. |..|. |.                |   ....| ..... .|.|.|.                       ..| 
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LIGSMLKVDPLERKSLENILKNDWF
|| .||.||| .| ..| .|.  |.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 85337.m00308.AA CAMKL 12-264 34 5.3e-100 319.84 In-house 1-297 (297) Show / Hide 
Range on Protein: 12-264
Range on HMM: 1-297/297
Sequence Identity: 34% (104 aa)

YKINGVIGSGAFATVYKAYNPEL-RRLFAIKCFKKSNLKN-------------SKEEETFQREIDTMAYMD---HPGLVKLHNIFEDENN------FYLV
|.|  ..| |.|..|  | .  . ..  |||  .|. ..|             .. .   .|||  |  ..   ||  .||. ..|....      .|||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

LDYCAGGE--LFDYILKK----KRLDEHTAALVFKQIVSAISYCHSFGIAHRDLKPENILIDKFP--KVMISDFGLCGYLKE-----STLMSTFVGSPIY
. || |||  ||||| |.    .|..|| |   |.|||||..|||| ||.|||.||||||.|.    .. |.|||.. . ..       ...|| ||| |
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

TAPECLQN--QEYDGRLSDIWSLGVILFGMVTGEHPWKTN--------NTAIMLKQIYNADFTYP--SYLSNDVKELIGSMLKVDPLERKSLENILKNDW
 ||| .|   ..|||.  ||||.||||. ||.|. |..          |.  ....|    . .|  ...| |.. || .||.|.| .| ....|..  |
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

F
.
M
S_TKc 85337.m00308.AA S_TKc 12-264 36 4.1e-99 336.48 SMART 1-231 (231) Show / Hide 
Range on Protein: 12-264
Range on HMM: 1-231/231
Sequence Identity: 36% (99 aa)

YKINGVIGSGAFATVYKAYNPELRRLFAIKCFKKSNLKNSKEEETFQREIDTMAYMDHPGLVKLHNIFEDENNFYLVLDYCAG--GELFDYILKKKR---
|.|  .||.|||..|||... .  |..|||. |          |...|||. .   .|| .|||. .|.| ...|.|..|| |  |.||||| |..|   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LDEHTAALVFKQIVSAISYCHSFGIAHRDLKPENILIDKFPKVMISDFGLCGYLKESTLMSTFVGSPIYTAPECLQNQEYDGRLSDIWSLGVILFGM
   ..| .|. ...||..|. |||| || ||||||||||.|.   ..|.||||.  |      .||.|.| | ||| |    |... .|.||.|.||. |
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

VTGEHPWKTNNTAIMLKQIYNADFTYPSYLSNDVKELIGSMLKVDPLERKSLENILK-------NDWF
..|. |.   . . |.|.|           | ..|..|  .|..|| .| .   .|.         ||
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 85337.m00308.AA MARK 12-264 39 2.7e-95 311.95 In-house 1-262 (262) Show / Hide 
Range on Protein: 12-264
Range on HMM: 1-262/262
Sequence Identity: 39% (104 aa)

YKINGVIGSGAFATVYKAYNPELRRLFAIKCFKKSNLKNSKEEETFQREIDTMAYMDHPGLVKLHNIFE--DENN-FYLVLDYCAGGELFDYILKK--KR
||.  .|| |..|.|..| .   .| .|||  .| .|   .. . ..|||. |  .|||  .||. ..|  .|.. .||...|. ||||.||| ..   |
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LDEHTAALVFKQIVSAISYCHSFGIAHRDLKPENILIDKFP--KVMISDFGLCGYLKESTLMSTFVGSPIYTAPECLQNQEYDGRLSDIWSLGVILFGMV
| |  |   |.|||||..|||| .|.|||.||||||||.    .. |.|||..   .. .. .|| |.| | ||| .. ..|||.  |||||||.|. ||
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

TGEHPWK--TNNTAIMLKQIYNADFTYPSYLSNDVKELIGSMLKVDPLERKSLENILKNDWF
.|  |..  |..   . |.|.. ....|...| . . || ..|.|.| || ..|.|.|  |.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 85337.m00308.AA AMPK 12-264 39 1.7e-93 277.96 In-house 1-254 (254) Show / Hide 
Range on Protein: 12-264
Range on HMM: 1-254/254
Sequence Identity: 39% (101 aa)

YKINGVIGSGAFATVYKAYNPELRRLFAIKCFKKSNLKNSKEEETFQREIDTMAYMDHPGLVKLHNIF-EDENNFYLVLDYCAGGELFDYILKKKRLDEH
| |   || |.|  |  ..    .   |||   |  .|...  |  ||||. .  . || ...|  .  | .  ...|. | .|||||||| |..||.|.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

TAALVFKQIVSAISYCHSFGIAHRDLKPENILIDKFPKVMISDFGLCGYLKESTLMSTFVGSPIYTAPECLQNQEYDGRLSDIWSLGVILFGMVTGEHPW
 |. .|.||.|...|||  .|.||||||||.|.|.  .. | ||||  . |.  . .|  ||| | |||  ... | |.  |||| ||||. |. |  | 
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

KTNNTAIMLKQIYNADFTYPSYLSNDVKELIGSMLKVDPLERKSLENILKNDWF
   ||.   | | | ... |..||...|.|| .||.|||..| . . | . .||
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 85337.m00308.AA Pkinase 12-264 32 7.3e-89 306.33 Pfam 1-293 (293) Show / Hide 
Range on Protein: 12-264
Range on HMM: 1-293/293
Sequence Identity: 32% (97 aa)

YKINGVIGSGAFATVYKAYNPELRRLFAIKCFKKSNLKNSKEEETFQR--EIDTMAYMDHPGLVKLHNIFEDENNFYLVLDYCAGG----ELFDYIL--K
|.| ..||||.|..|||...   ....|.|..||.  ..|....|  |  ||  |. ..||  |.|. .|||... |.|..|| ||    .|||||   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

KKRL--DEHTAALVFKQIVSAISYCHSFGIAHRDLKPENILIDKFPKV----MISDFGLCGY--LKESTLMSTFVGSPIYTAPECLQNQEYDGRLSDIWS
....  .|...  ...||.... |||| || ||||||||||||. . .     |.||||.    .  .. |.||.|.| | ||| .. ..|.|. .|.||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGVILFGMVTGEHPWKTN------NTAIMLKQIYNADFTYPSYLS---------------------NDVKELIGSMLKVDPLERKSLENILKNDWF
.|.||. |..|. |..        .   |...|  ... .... .                      . |..| ..|..|| .| . | ||. .||
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 85337.m00308.AA Ciliate-E2 12-264 26 1.7e-88 300.35 In-house 1-365 (365) Show / Hide 
Range on Protein: 12-264
Range on HMM: 1-365/365
Sequence Identity: 26% (100 aa)

YKINGVIGSGAFATVYKA---YNPELR--------------------RLFAIKCFKKSNLKNSKEEETFQREID----------TMAYMDHPGLVKLHNI
||.. .||.|.|..|||.    ....                      ..|.|..||..... | |.   |||.           .  ..|| ..|..  
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--DENNFYLVLDYCAGGELFDYILKK-----------KRLDEHTAALVFKQIVS---------------AISYCHSFG-IAHRDLKPENILIDKFPKV
|.  |.||.|||..|| ||.||||| ..           |...|  .. ..|||..               |. |.|| . | |||.||||||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

MISDFGLCGYLKES--------------------------------TLMSTFVGSPIYTAPECLQNQEYDG--------RLSDIWSLGVILFGMVTGEHP
 |.||||. .....                                 .  |..|.| | ||| |....||.          .|||||||||. |..|..|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

WKTNNTAIMLKQIYNADFTYP------------------SYLSNDVKELIGS----MLKVDPLERKS-LENILKNDWF
.        ..|| . .. .|                   ..|...| ||      ||..|| .| .  | ||.. ||
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 85337.m00308.AA CAMK1 12-264 36 1.8e-86 251.38 In-house 1-276 (276) Show / Hide 
Range on Protein: 12-264
Range on HMM: 1-276/276
Sequence Identity: 36% (101 aa)

YKINGVIGSGAFATVYKAYNPEL---RRLFAIKCFK-KSNLKNSKEE--ETFQREIDTMA---YMDHPGLVKLHNIFEDENNFYLVLDYCAGGELFDYIL
|..  .||.|||..||.. . |     . .||||.. |...|....   | ...||. |      |||  .|.. ..|..| ||||.... |||||| |.
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

KKKRLDEHTAALVFKQIVSAISYCHSFGIAHRDLKPENIL-IDKFPK--VM--ISDFGLCGYLKEST-LMSTFVGSPIYTAPECLQN---QEYDGRLSDI
.|.   |  |... |||.||. |.|| ||.||||||||.|  || .   ..  |.||||  ....   ||.| .|.| | ||| | .   . ||    |.
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKAC-DM

WSLGVILFGMVTGEHPWKTNN-TAIMLKQIYNADFTYPSY----LSND-VKELIGSMLKVDPLERKSLENILKNDWF
|| |||.. . .|  |   .|  . ....| ......||      |.  .|..|  ||.||| .| . | .|.  |.
WSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase 85337.m00308.AA ULK 12-264 30 1.6e-77 263.9 In-house 1-324 (324) Show / Hide 
Range on Protein: 12-264
Range on HMM: 1-324/324
Sequence Identity: 30% (99 aa)

YKINGVIGSGAFA-TVYKAYNPEL---RRLFAIKCFKKSNLKNSKEE-------ETFQREIDTMAYMD---HPG--LVKLHNIFEDE--NNFYLVLDYCA
| .| ..|.|.|. .|||..| .      ..|.|.  |......| |       . ...|| .|  ..   ||    |||. .||.   ||.|....|| 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGELFDYILKKKRLDEHT----------AALVFKQIVSAISYCHSFGIAHRDLKPENILIDK-FPK-----------VMISDFGLCGYLKES----TLMS
|| |..|| |.|.| | |          |  .||||...  . |. .| |||.||.|||| . .||           . |.|||..  . .     ... 
GGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

TFV------GSPIYTAPECLQ----NQEYDGRLSDIWSLGVILFGMVTGEHPWKTN-NTAI----MLKQ--------IYNADFTYP-----SYLSNDVKE
|.|      |.|.| ||. ||    ...|.   .||||||.|.. |..|. |.... |. .     |..        |.|  . .|       .|...|.
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LIGSMLKVDPLERKSLENILKNDWF
||  ||..|. .| | | |... ||
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 85337.m00308.AA Ciliate-E2-Unclassified 12-264 28 1.5e-76 260.61 In-house 1-352 (352) Show / Hide 
Range on Protein: 12-264
Range on HMM: 1-352/352
Sequence Identity: 28% (100 aa)

YKINGVIGSGAFATVYKAYNPELRRLFAIKCFKKSNLKNSKEEET---FQREIDTMAY-------------------MDHPGLVKLHNIFEDENNFYLVL
|||. .||.|.|..|||... .   ..|.|  ||.. ...|  ..   . .|...|                     ..|| .||.. .|.|..|.|.|.
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

DYCAGGELFDYILKK-----------------KRLDEHTAA-----LVFKQIVSAISYCHSFG-IAHRDLKPENILIDKFP---KVMISDFGLCGYLKE-
.|| ||.|..|| |.                 |...|  |.       |.||.....|.|. . | |||.||||||.|.     .. |.|||.. .... 
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

---------------STLMSTFVGSPIYT----APECLQNQEYDGR---LSDIWSLGVILFGMVTGEHPWKTNNTAI----------------MLKQIYN
               . .|.||.|.|.|     |||.||.|.||..    .|||||||||. |..|..| . ||  .                ....|..
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

ADFTYPS--------YLSNDVKELIG----SMLKVDPLERKSLENILKNDWF
 .. .|.         .|. .|..|     .|||..| .| ..| ||.  ||
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 85337.m00308.AA QIK 12-264 35 8.8e-75 254.75 In-house 1-272 (272) Show / Hide 
Range on Protein: 12-264
Range on HMM: 1-272/272
Sequence Identity: 35% (97 aa)

YKINGVIGSGAFATVYKAYNPELRRLFAIKCFKKSNLKNSKEEETFQREIDTMAYMDHPGLVKLHNIFEDENNFYLVLDYCAGGELFDYILKKKR-----
| |   || | ||.|  | .       |||   || |  .  . .. ||.  |  ..||  .|| .. | ..  |.| .|| .||.|||. |. |     
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCY-REVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------LDEHTAALVFKQIVSAISYCHSFGIAHRDLKPENILIDKFPKVMISDFGLCGYLKESTLMSTFVGSPIYTAPECLQNQEYDGRLS
               . |  |. .|.||.||. |||. .|.||||| ||||.|.   . | |||.  . |.  |..|..||| | ||| .. .||||  .
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKV

DIWSLGVILFGMVTGEHPWKTNNTAIMLKQIYNADFTYPSYLSNDVKELIGSMLKVDPLERKSLENILKNDWF
||||.||.|. .|.|  |    .   . . .    |  | ..| |  .||  || |||  | . ..|..  | 
DIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase 85337.m00308.AA ULK 12-264 29 2.1e-74 253.49 In-house 1-329 (329) Show / Hide 
Range on Protein: 12-264
Range on HMM: 1-329/329
Sequence Identity: 29% (97 aa)

YKINGVIGSGAFATVYKAYNPELR----RLFAIKCFKKSNLKNSKEEET-------FQREIDTMAYMD--------HPGLVKLHNIFEDE--NNFYLVLD
| .| ..|.|.|..|||..| .       ..|.|   |. ..... | .       ...||..|  ..        ||  |||. .||.   ||.|....
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCAGGELFDYILKKKRLDEHT----------AALVFKQIVSAISYCHSFGIAHRDLKPENILIDK-FPK-----------VMISDFGLCGYLKEST----
|| || |..|| |.|.| | |          |  .||||...  . |. .| |||.||.||||.. .||           . |.|||..  . ...    
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

LMSTFV------GSPIYTAPECLQ----NQEYDGRLSDIWSLGVILFGMVTGEHPWKTN-NTAI-----MLKQ--------IYNADFTYPSY-----LSN
.| |.|      |.|.| ||. ||    ...|.   .||||||.|.. |..|. |.... |. .      |..        | .  . .| .     .|.
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

DVKELIGSMLKVDPLERKSLENILKNDWF
..|.||  ||..|. .| | | .... ||
ECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 85337.m00308.AA TyrKc 12-263 22 1.7e-16 44.02 SMART 1-280 (280) Show / Hide 
Range on Protein: 12-263
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

YKINGVIGSGAFATVYKAYNPELRRLFAIKCFKKSNLKNSKEEETFQREIDTMAYM--DHPGLVKLHNIFEDE-------NNFYLVLDYCAGGELFDYIL
 . . ..|.||| .|||.      .  |.|. |..       .| | ||.  |     .|| .|.|. .  ..          ..|. |...| | ||. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KKKR-LDEHTAALVFKQIVSAISYCHSFGIAHRDLKPENILIDKFPKVMISDFGLCGYLKES--------TLMSTF--VG---SPI-YTAPECLQNQEYD
|... |   .      || .  .| || .. ||||   |.|...   | ||||||. ....         . ...    |    ||  .||||..  .. 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

GRLSDIWSLGVILFGMVT-GEHPWKT-----NNTAIMLKQIYNADFTYPSYL---------SNDVKELIGSMLKVDPLERKSLENILKNDW
   ||.|| || .. . | |. |.        . . ..... . .   .            . .. ... .  . || .| . ..| . ..
-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase 85337.m00308.AA Pkinase_Tyr 12-211 28 1.8e-14 49.64 Pfam 1-217 (270) Show / Hide 
Range on Protein: 12-211
Range on HMM: 1-217/270
Sequence Identity: 28% (62 aa)

YKINGVIGSGAFATVYKAYNP----ELRRLFAIKCFKKSNLKNSKEE---ETFQREIDTMAYM-DHPGLVKLHNIFE-DENN--FYLVLDYCAGGELFDY
 ... ..|.||| .|||..      . .   |.|. |    . ..|.   | | ||. .|  . .|| .|.|. .   ..     |.|. |...| | ||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE---GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

ILK----KKRLDEHTAALVFKQIVSAISYCHSFGIAHRDLKPENILIDKFPKVMISDFGLCGYL--KEST-LMSTFVGSPI-YTAPECLQNQEYDGRLSD
  |    |..|. ..      || .. .| .| .. ||||   |.|...  .| |.||||. ..  ..    ...    ||  .||||... ..    ||
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFT-TKSD

IWSLGVILFGMVT-GEHP-WK
.|| || .. ..| || | ..
VWSFGVLMWEIFTYGEQPTYP