Gene 97360.m00056 (T.vaginalis)

97360.m00056

Species: T.vaginalis
Alias: TvagK0777, 97360.m00056
External Links:
Annotation:

Classification

Group: Other
Family: PLK
Subfamily: PLK1

Sequence

Name Sequence Type Origin Length Description Download
97360.m00056.AA Protein None 526 None Fasta, JSON
97360.m00056.kin_dom Protein Kinase Domain None 257 None Fasta, JSON

Protein domain

Protein domains of 97360.m00056.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 97360.m00056.AA PLK 22-278 45 6e-123 402.16 In-house 1-258 (258) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-258/258
Sequence Identity: 45% (117 aa)

YKKQDVLGIGGFATVYKVFEKSTSQEYAMKVIPKDRITKPKAQERLKLEIQIQSALHHPNVLRSYGAFEDATNHYIVTELCPGLSIRDLLKKK-GNLTEF
|... .|| |||| .|.. . .|.|.|| ||.|| ...||.. |..| ||.|.. |||||... .  |||. | ||| |.|.. |  ...|..   ||| 
YERGHFLGKGGFAKCYEMTDIHTKQVYAIKVVPKSLMQKPHQREKMKQEIEIHRQLHHPNIVKFHHFFEDHENVYIVLEYCHNRSLMHYHKRRAKRLTEP

ETVKVIKDVLEGLVYLHDNRVIHRDIKLENFLVGKDGRVKIADFGLSTKLSYDDEKKYTVCGTPNYLSPEILADASKGHSYEVDIWAIGVSVYAMLIGRP
|.   .  . .|| |||..|.||||.|| |..  .. .|||.||||.|.| ||.|.|.|.|||||| .||.|    .|||||||.|..|. .|..|||.|
EVRYYMYQIVQGLKYLHQHRIIHRDLKLGNLFLNDNMHVKIGDFGLATRLEYDGERKKTMCGTPNYIAPEVLDGNKQGHSYEVDCWSLGCIMYTLLIGKP

PFQTARTKLTYEHIKTCSYLFPVEPKISQAARDFIKSTLQIKPELRPTAQELLYHEFI
||.|.. | ||. || . | || .. ||..|.|.|.. |.  |. |||. ..| |.| 
PFETKDVKETYKRIKHNHYSFPEHCPISDEAKDLIQKMLNWNPDERPTIDQILQHPFF
Kinase 97360.m00056.AA PLK-Unclassified 22-278 43 2.4e-112 379.56 In-house 1-264 (264) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-264/264
Sequence Identity: 43% (116 aa)

YKKQDVLGIGGFATVYKVFEKSTSQEYAMKVIPKDRITKPKAQERLKLEIQIQSALHHPNVLRSYGAFEDATNHYIVTELCPGLSIRDLLKKK-------
|..   || |||| .|.| . .| ..|| |.|||  .|| .| ..|. ||.|.. |||.|. . .  |||  | ||. |.||. .. ...|..       
YHRGHFLGKGGFAKCYQVKNIETKKIYAAKIIPKSSLTKNRARQKLISEIKIHKSLHHKNIVKFEHCFEDHENVYILLEYCPNGTLMEYIKRRNFQLFEK

GNLTEFETVKVIKDVLEGLVYLHDNRVIHRDIKLENFLVGKDGRVKIADFGLSTKLSYDDEKKYTVCGTPNYLSPEILADASKGHSYEVDIWAIGVSVYA
  ||| |.      ....| |||.||.|||| || | ... . .|||.||||.||| .| |||.|.|||||| .||||    .|||||||.|..|. .|.
KRLTEYEVKCYTYQIVQALKYLHQNRIIHRDLKLGNIFLNDNMEVKICDFGLATKLENDGEKKKTICGTPNYIAPEILDGKHQGHSYEVDCWSFGCILYT

MLIGRPPFQTARTKLTYEHIKTCSYLFPVEPKISQAARDFIKSTLQIKPELRPTAQELLYHEFI
.|||.|||.|   | ||. ||. .| || ...|| .|.|.|.. |.. |. |||  ... | | 
LLIGKPPFETKDVKQTYKKIKCNQYSFPEPCHISDNAKDLIQHILNWNPDQRPTIDQIMMHPFY
Kinase 97360.m00056.AA AGC 22-278 21 1.2e-99 257.68 In-house 1-395 (395) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-395/395
Sequence Identity: 21% (88 aa)

YKKQDVLGIGGFATVYKVFEK------STSQEYAMKVIPKDR-ITKPK--AQERLKLE------------IQIQSALH----------HPNVLR-SYGAF
..   |.| |.| .|| | .|      .| . |||||. |.. | . |   .|. . |             .| . ..          ||.. .  . .|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

EDATN--HYIVTELCP----------GLSIRDLLK---KKGNLTEFETVKVIKD-------VLEGLVYLHD-NRVIHRD-IKLENFLVGKDGRVKIADFG
.| ..   |.| |..|          |.     |.   |.| ..| ..   .         .. .| |||. . .|||| .|.|| |  .|| .|..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSTKLSYDD--------------------------------------------------EKKYTVCG--TPNYLSPEILADASKGHSYEVDIWA--IGVS
|....  |.                                                  .. .| ||  ||.|..||||      .....|.|.   |. 
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL------YGKACDWWSFGLGCL

VYAMLIGRPPFQTAR----------TKLTYEHIK------TCSYLFP--------VEPKISQAARDFIKSTLQIKPELRPT----------AQELLYHEF
 | ||.|.|||.              . ... |.      ..   ||         ....|. |.|.||  |.  || |..          |.|.  |..
MYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPW

I
 
F
Kinase 97360.m00056.AA S_TKc 22-278 32 1.6e-97 331.2 SMART 1-231 (231) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-231/231
Sequence Identity: 32% (89 aa)

YKKQDVLGIGGFATVYKVFEKSTSQEYAMKVIPKDRITKPKAQERLKLEIQIQSALHHPNVLRSYGAFEDATNHYIVTELCPG--LSIRDLLKKKGN---
|.. ...| |.|..|||. .|.| ...|.|.|.          |... |||| .  ||||. . |..|.| .. |.|.|.|.|   . .|..||.|    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LTEFETVKVIKDVLEGLVYLHDNRVIHRDIKLENFLVGKDGRVKIADFGLSTKLSYDDEKKYTVCGTPNYLSPEILADASKGHSY-EVDIWAIGVSV
   ..| .. .... ....| |.|....||||.| || |. .  ..||.||||...|       .|.||||.|..||.|     |... ..|.|..|. .
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCIL

YAMLIGRPPFQTARTKLTYEHIKTCSYLFPVEPKISQAARDFIKSTLQIKPELRPTAQELLY-------HEFI
| || |.|||.    ......|.            |. |.|||.  ||  || |||| |.|        |...
YEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 97360.m00056.AA CAMK 27-278 20 3.3e-95 307.22 In-house 1-425 (425) Show / Hide 
Range on Protein: 27-278
Range on HMM: 1-425/425
Sequence Identity: 20% (87 aa)

VLGIGGFATVYKVFEKSTS------------QEYAMKVIPKDRITK-------------------------PKAQERLKLEIQIQSA-------LHHPNV
.|| |.|..|.....|.|             |..|.|.|.|.....                         || ..... ||.| .        |.|||.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LRSYGAFEDATN-------------------HYIVT---ELCPGL----SIRDLLKKKGN---------------LTEFETVKVIKDVLEGLVYLHDNRV
.. | ..||...                    |.|.   |.|.|      . | ....|.               .|| |. .... ..... |.|.. .
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDIKLENFLVGKD-----------------GRVKIADFGLSTKLSY-----------------------DDEKKYTVCGTPNYLS-PEILADA-----
.|||.|.|| |. ..                 . .||.|||...|.                         ...| .|.|||| | . ||.|        
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------SKGHSYEVDIWAIGVSVYAMLIGRPPFQTA-------------RTKLTYEHIKTCSYLFPVEPK--------------ISQA--------ARD
        .......|.|..||  |.|| |.|||.                 . ..| |... | || ..               ||.         ..|
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

FIKSTLQIKPELRPTAQELLYHEFI
.|.. ||  || |.|... | |...
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 97360.m00056.AA PLK1 22-278 44 7.3e-93 305.59 In-house 1-253 (253) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-253/253
Sequence Identity: 44% (114 aa)

YKKQDVLGIGGFATVYKVFEKSTSQEYAMKVIPKDRITKPKAQERLKLEIQIQSALHHPNVLRSYGAFEDATNHYIVTELCPGLSIRDLLKKKGNLTEFE
|.|   || ||||  | . .|.| . .| ||.||  . |.......  ||||   |||... . .  |||  | ||| |||   |. .| |... .||.|
YEKGRFLGKGGFAHCYEIRDKDTKEVFAGKVVPKSLLIKQHQRDKMTQEIQIHRQLHHRHIVKFHHFFEDKQNVYIVLELCRRRSLMELHKRRKAITEPE

TVKVIKDVLEGLVYLHDNRVIHRDIKLENFLVGKDGRVKIADFGLSTKLSYDDEKKYTVCGTPNYLSPEILADASKGHSYEVDIWAIGVSVYAMLIGRPP
.   .. ..||  |||.|..||||.|| |  .  . .||| |||| ||. || |.| | ||||||. ||.|..  ||||.|||||.||  .| .|.|.||
CRYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGDFGLATKCEYDGERKKTLCGTPNYIAPEVLNK--KGHSFEVDIWSIGCIMYILLFGQPP

FQTARTKLTYEHIKTCSYLFPVEPKISQAARDFIKSTLQIKPELRPTAQELLYHEFI
| | . | || .|| . |  | .  |||.|...|.. |. .|. |||....|  ||.
FETKCLKETYSRIKKNEYRIPSH--ISQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF
Kinase 97360.m00056.AA Pkinase 22-278 31 8e-93 319.48 Pfam 1-293 (293) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-293/293
Sequence Identity: 31% (92 aa)

YKKQDVLGIGGFATVYKVFEKSTSQEYAMKVIPKDRITKPKAQERLK-LEIQIQSALHHPNVLRSYGAFEDATNHYIVTELCPGL----SIRDLLK--KK
|..  ..| |.|..|||  .|.|....|.|.|.|... . | |....  ||||   |.|||..| |..||| .. |.|.|.|.|     .  |...  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GNL--TEFETVKVIKDVLEGLVYLHDNRVIHRDIKLENFLVGKDGRV----KIADFGLSTKL-SYDDEKKYTVCGTPNYLSPEILADASKGHSYEVDIWA
|..  .| |  .... .|.|| |.|....||||.|.||.|. ..| .    ||.||||. ..    ..  .|.||||.|..||..   .......||.|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-GGQYYGPKVDMWS

IGVSVYAMLIGRPPFQTA------RTKLTYEHIKTCSYLFPVEPKIS-------------------QAARDFIKSTLQIKPELRPTAQELLYHEFI
.|. .| || |||||. .      . .  .. |. . . |. . ..|                   ....||||. |. .|. ||||...| |...
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 97360.m00056.AA CAMKL 22-278 28 1.8e-85 272.72 In-house 1-297 (297) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-297/297
Sequence Identity: 28% (87 aa)

YKKQDVLGIGGFATVYKVFE-KSTSQEYAMKVIPKDRIT-KPKAQER-----------LKLEIQIQSALH---HPNVLRSYGAFEDATN------HYIVT
|.  ..|| |.|..|      . | ...|.|.| |..|. .|... .           .. ||||.. |.   |||. . |  .|. ..       |.|.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELCPGLS--IRDLLKKKGN----LTEFETVKVIKDVLEGLVYLHDNRVIHRDIKLENFLVGKDG--RVKIADFGLSTKLS-Y---DDEKKYTVCGTPNYL
|.|.| .    | ..|.|.    ..| |. .  . ..... |.|.....|||||.|| |. ..|   .||.|||.|..   .   ...|  | ||.|.| 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

SPEILAD-ASKGHSYEVDIWAIGVSVYAMLIGRPPFQTA--------RTKLTYEHIKTCSYLFPVEPKISQAARDFIKSTLQIKPELRPTAQELLYHEFI
.|||...   . . ..||||..||  |||. |. ||  .         . . |. |... | .|. ...|  .||.|.. || .|| |||..... |.. 
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 97360.m00056.AA Ciliate-E2 22-278 27 1.1e-79 271.03 In-house 1-365 (365) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-365/365
Sequence Identity: 27% (103 aa)

YKKQDVLGIGGFATVYKVFEKSTSQEYAMKVIPKDR------------------ITKPKAQERLKLEIQIQSALH----------------HPNVLRSYG
||.. ..| |.|..|||.  ... ...|.|.|  .                   | |..  | .| ||.|   ..                |||... | 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

AFE--DATNHYIVTELCPGLSIRDLLKKK-----------GNLTEFETVKVIKDVLE---------------GLVYLHDNR-VIHRDIKLENFLVGKDGR
.|.  | .| |.|.|.| | . .|..|..           ...||.|  ...| .|.               .| ||| .  .||||||.|| |.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

VKIADFGLSTKLSYDDEKK-------------------------------YTVCGTPNYLSPEILADAS-------KGHSYEVDIWAIGVSVYAMLIGRP
.||.|||||.|.. | ...                               .|.||||.|..||||   .       ||..|..|||..||  | || |.|
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFQTARTKLTYEHIKTCSYLFP----------------VEPKISQAARDFIKS----TLQIKPELRPT-AQELLYHEFI
||        .. || | . ||                   |.|| . |.||      || .|| |.| ....| |...
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 97360.m00056.AA STE 22-278 22 4.9e-77 262.24 In-house 1-359 (359) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-359/359
Sequence Identity: 22% (82 aa)

YKKQDVLGIGGFATVYKVFEK------STSQE---------YAMKVIPKDRITK--------------PKAQERLKLEIQIQSALH--HPNVLRSYGAFE
.......| |.| ||||   .      .| ..         .|.|...... ..              .. ..... ||.| . ..  |||. . ||...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DA-------TNHYIVTELCPGLSIRDLLKKK----GNLT----------EFETVKVIKDVLEG-LVYLHDNRVIHRDIKLENFLVGKDGRVKIADFGLST
.        .. .|. |...| |..|..|.|    ..|.          | .  ......|.| | |||....||||||  | |.     ||..|||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

KLSYD----------------DEKKYTVCGTPNYLSPEILADA----SKGHSYEVDIWAIGVSVYAMLIGRPPFQT-ARTKLTYEHI-------------
.|. .                ..| .|..||| . .||..       .||... .||| .|  .  |. |.||. .   ..  .. .             
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---KTCSYLFPVEP----------------KISQAARDFIKSTLQIKPELRPTAQELLY--HEFI
   ...  | .                   | |.  .|||.  ||. |. ||||..||   |.||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 97360.m00056.AA PLK2 22-278 39 5.2e-77 247.48 In-house 1-257 (257) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-257/257
Sequence Identity: 39% (102 aa)

YKKQDVLGIGGFATVYKVFEKSTSQEYAMKVIPKDRITKPKAQERLKLEIQIQSALHHPNVLRSYGAFEDATNHYIVTELCPG----LSIRDLLKKKGNL
| .  .|| ||||  |.    .|.  ||.|..|. |. ||.  |    || . . |.|... . .  |||. | ||. |.|       |.   .|    |
YCRGKLLGKGGFARCYEMTDMDTHYVYAVKIVPHSRVAKPHQREKMEREIELHRQLRHRHIVQFHHHFEDRDNIYILLEYCSRQVPLKSMAHMWKVRHHL

TEFETVKVIKDVLEGLVYLHDNRVIHRDIKLENFLVGKDGRVKIADFGLSTKLSYDDEKKYTVCGTPNYLSPEILADASKGHSYEVDIWAIGVSVYAMLI
|| |    .. ...|| |||. ..|||| || || . .   ||| ||||  .|    . . | ||||||..||.|    .||| | |||| |   | ||.
TEPEVRYYMRQIVSGLRYLHQQCIIHRDLKLGNFFINDNMEVKIGDFGLAARLEPEEHCHRTMCGTPNYIAPEVL--NRQGHSCESDIWALGCIMYTMLC

GRPPFQTARTKLTYEHIKTCSYLFPVEPKISQAARDFIKSTLQIKPELRPTAQELLYHEFI
||||| ||  | ||  |.   |..|     |  ||  | . |   || ||   ... |.| 
GRPPFETANLKETYRCIRHNHYHMPTH--LSPPARHLIARMLSPDPEDRPSLDHIIRHDFF
Kinase 97360.m00056.AA Ciliate-E2-Unclassified 22-278 25 2.6e-75 256.5 In-house 1-352 (352) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-352/352
Sequence Identity: 25% (92 aa)

YKKQDVLGIGGFATVYKVFEKSTSQEY-----AMKVIPKDRITKPKAQERLKLEIQIQSALH-------------------HPNVLRSYGAFEDATNHYI
||.. ..| |||..|||. .|..  .|     ..|.. ...  . . . ....|...   .                    ||.... . .|.|  | ||
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VTELCPGLSIRDLLKKKGN-----------------LTEFETV-----KVIKDVLEGLVYLHDN-RVIHRDIKLENFLVGKDG---RVKIADFGLSTKLS
|.|.|.|.. .. .||...                 .||....     . .. .|.|| ||| .  .||||||.|| |. ..|   ..||.|||.| |. 
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

YD---------------DEKKYTVCGTPNYL----SPEILADASKGHS--YEVDIWAIGVSVYAMLIGRPPFQ-TARTK---------------LTYEHI
..               ... .|.||||||.    .||.|     .||  |..|||. ||  |.|| |..||. . ...                 |. |
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

KTCSYLFPVEP------KISQAARDFIK----STLQIKPELRPTAQELLYHEFI
| . . || .|      ..|. | |||.    . |. .|. |.|....| | ..
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 97360.m00056.AA TyrKc 22-278 24 1.9e-26 95.1 SMART 1-280 (280) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-280/280
Sequence Identity: 24% (72 aa)

YKKQDVLGIGGFATVYKVFEKSTSQEYAMKVIPKDRITKPKAQERLKLEIQIQSAL--HHPNVLRSYGAFEDA-------TNHYIVTELCPGLSIRDLLK
 .. ..|| | | .|||   |   .. | |.. .|       .| .  |..| . |  ||||..| ||.  .          ..||.|..|. . .| |.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KKGN-LTEFETVKVIKDVLEGLVYLHDNRVIHRDIKLENFLVGKDGRVKIADFGLSTKLSYD----DEKKYTVC----GTP-----NYLSPEILADASKG
|... |.  . ..   .. .|  |||....||||.   | |||....|||.||||| ..  |     .|.| .     |.        ..|| .    . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYGK

HSYEVDIWAIGVSVY--AMLIGRPPFQT----ARTKLTYEHIKTCSYLFPVEP-------KISQAARDFIKSTLQIKPELRPTAQELLYHEFI
 . . |.|. ||  .    . . |.          .  .|..|.  .. . .          ...  . .|.  . .|| ||| .|.  ||..
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 97360.m00056.AA Pkinase_Tyr 22-175 31 5.6e-24 81.84 Pfam 1-165 (270) Show / Hide 
Range on Protein: 22-175
Range on HMM: 1-165/270
Sequence Identity: 31% (53 aa)

YKKQDVLGIGGFATVYKVFEK----STSQEYAMKVIPKDRITKPKA--QERLKLEIQIQSAL-HHPNVLRSYGAFE-DATN--HYIVTELCPGLSIRDLL
 ..  .|| | | .|||   |    .| .. | |.. |.  . ...  .| .  |..| . | ||||..| ||.   .     .|||.|..|. . .| |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

KK----KGNLTEFETVKVIKDVLEGLVYLHDNRVIHRDIKLENFLVGKDGRVKIADFGLSTKLSYDDE
.|    |..||  . ..   .. .|. ||.... ||||.   | ||.... |||.||||.  . |.|.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDD
POLO_box 97360.m00056.AA POLO_box 352-388 35 1.3e-09 39.14 Pfam 1-39 (74) Show / Hide 
Range on Protein: 352-388
Range on HMM: 1-39/74
Sequence Identity: 35% (14 aa)

HAEKYGLGYLLIDGTIGAC-FNDSSRMIMDPHEE-FVQY
   |||..|.| .||.. . |||....|..|... .|.|
YRTKYGIMYQLSNGTVQVNFFNDHTKIILCPNMKYAVTY
POLO_box 97360.m00056.AA POLO_box 448-475 37 0.00316 15.52 Pfam 1-29 (74) Show / Hide 
Range on Protein: 448-475
Range on HMM: 1-29/74
Sequence Identity: 37% (11 aa)

IRTDYATLFRMENRDIQVN-FTDKIKIVI
 ||.|.  ... | ..||| |.|. ||..
YRTKYGIMYQLSNGTVQVNFFNDHTKIIL