Gene 93576.m00082 (T.vaginalis)

93576.m00082

Species: T.vaginalis
Alias: 93576.m00082, TvagK0706
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
93576.m00082.AA Protein None 190 None Fasta, JSON
93576.m00082.kin_dom Protein Kinase Domain None 165 None Fasta, JSON

Protein domain

Protein domains of 93576.m00082.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase 93576.m00082.AA Pkinase 13-152 27 3.1e-23 83.25 Pfam 1-158 (293) Show / Hide 
Range on Protein: 13-152
Range on HMM: 1-158/293
Sequence Identity: 27% (43 aa)

YKLISEIGSGKFSHCYLCKSIKYELEFVAKVIPGCSDDI----QNVL--EMEVQSKLAHSNIVNIYDKFIEFNYCVLILEYCNNG----NLSSLFK--LS
|.... |||| |. .|.|. .... ... |.|. ....     ....  | ..  .| | ||| .|| | . ... ...|||..|     |... .   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KES--DPFVIQCIACQILDVLAFAHDEGMQHFGLNPNNIFVD-KFNI---VKISDFGI
.    .. ...... |||  |.. |..|  |  | | ||..| . .|   |||.|||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGL
Kinase 93576.m00082.AA Ciliate-E2-Unclassified 13-179 19 1.4e-20 68.12 In-house 1-240 (352) Show / Hide 
Range on Protein: 13-179
Range on HMM: 1-240/352
Sequence Identity: 19% (47 aa)

YKLISEIGSGKFSHCYLCKSIKYELEFVAKVIPGCSDDIQNVLEM-----------EVQSK------------------LAHSNIVNIYDKFIEFNYCVL
||.|  ||.| |.  |.|. .|   .. |.    ..  |.... .           |...|                  . | .||. .. |   ... .
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAM-KYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

ILEYCNNGNLSSLFKLSKE-----------------SDPFVIQ-----CIACQILDVLAFAHDEG-MQHFGLNPNNIFVDKFN---IVKISDFGI-----
..|||..|.|.   | .|                   . . ..      .. |||. | . | ..   |  . |.||..|. .    .||.||||     
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

-----------------DQILSLN--STSYQHNRPIEYLAPEIFTN
                 .|... .  . .|.  .   |.|||.. .
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMP-Q---YTAPEVLQG
Kinase 93576.m00082.AA Ciliate-E2 13-179 18 1e-18 60.89 In-house 1-261 (365) Show / Hide 
Range on Protein: 13-179
Range on HMM: 1-261/365
Sequence Identity: 18% (50 aa)

YKLISEIGSGKFSHCYLC---------------------------KSIKYELEFVAKVIPGCSDDIQNVL-----------EMEVQSKLAHSNIVNIYDK
||.|  ||.| |.  |.|                           |. .|... . |        .....           |......| | ||...|. 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FI--EFNYCVLILEYCNNGNLSSLFKLSKESDP-----------FVIQCIACQILD---------------VLAFAHDEG-MQHFGLNPNNIFVDKFNIV
|.    |.. |..|||. |.| .. | .| . .           . |. |  |||.                | . | ..   |  . |.||..     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KISDFGIDQILSLN---------STSYQHNR------------------------PIEYLAPEIFTN
||.|||. .... .         .  |.  .                          .|.||||. .
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNG
Kinase 93576.m00082.AA CAMK 18-151 17 3e-18 54.76 In-house 1-241 (425) Show / Hide 
Range on Protein: 18-151
Range on HMM: 1-241/425
Sequence Identity: 17% (43 aa)

EIGSGKFSHCYLCKSIKYE------------LEFVAKVIP---------------------GCSD--------DIQNVL-EMEVQSKLA-------HSNI
..|.| |.  .||. ..               .. .|.|.                     .|..        | .||. |.|. .||        | ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VNIYDKFI------------EFNY--------CVLIL---EYCNNGNL-SSLFKLSKES---------------DPF---VIQCIACQILDVLAFAHDEG
...|. .               ..        .....   ||| .| |   ||   .|                  |     . .  ||.. ... |. .
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

MQHFGLNPNNIFVDKF-----------------NIVKISDFG
  |  | | || .|.                  | .||.|||
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFG
Kinase 93576.m00082.AA STE 13-152 19 1.2e-15 51.8 In-house 1-193 (359) Show / Hide 
Range on Protein: 13-152
Range on HMM: 1-193/359
Sequence Identity: 19% (38 aa)

YKLISEIGSGKFSHCYLCKSIK---YELE-------------FVAKVIP--GCS----------------DDI-QNVLEMEVQSKLA--HSNIVNIYDKF
...|..||.| |   |... .|   .. .             .  |...   |.                ... |   |... .|.   | |||. |. .
WEGIEKIGKGAFGTVYKAMNHKNCNIH-KTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

IEF-------NYCVLILEYCNNGNLSSLFK---LSKESDP-----------FVIQCIACQILDV-LAFAHDEGMQHFGLNPNNIFVDKFNIVKISDFGI
.         ... ...||...| |... |     .....            .| .|..|||   |.. |. .  |  . | ||..     ||..|||.
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGV
Kinase 93576.m00082.AA ULK 13-151 22 1.2e-13 44.85 In-house 1-183 (324) Show / Hide 
Range on Protein: 13-151
Range on HMM: 1-183/324
Sequence Identity: 22% (42 aa)

YKLISEIGSGKFSHCYLCKSIKYEL----EFVA-KVIPGCSDDIQNVL------------EMEVQSKLA---HSN--IVNIYDKFIEF--NYCVLILEYC
| |. ..|.| |   . .| .. .     ..|| |.|. ..  ... .            | ... ||    | |  ||  || | .   |.. .|.|||
YCLNHCLGKGSFG-VKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYC

NNGNLSSLFKLSKE---------SDPFVIQCIACQILDVLAFAHDEGMQHFGLNPNNIFVDKFN------------IVKISDFG
| |.|... |  |.              .. .  ||.  . . |...  |  . | || . . .            ..||.|||
NGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFG
Kinase 93576.m00082.AA NEK 13-152 28 1.4e-13 44.54 In-house 1-169 (286) Show / Hide 
Range on Protein: 13-152
Range on HMM: 1-169/286
Sequence Identity: 28% (49 aa)

YKLISEIGSGKFSHCYLCKSIKYELE-----FVAKVIPGCS----DDIQNVL--EMEVQSKLAHSNIVNIYDKFIEFN--YCVLILEYCN-NGNLSSLFK
|..| .||.| |. .|...... . .     .| | |   .     . || .  |  . ..| | |||  || ||| .  .   . |||. .|.|. ..|
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKIN-MGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIK

L----SKESDPFV---IQCIACQILDVLAFAHDE-----GMQHFGLNPNNIFVDKFNI----VKISDFGI
      .. ..|    |  . .|..  | . ||.        |  . |.||| .| |.    ||| ||||
SIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGI
Kinase 93576.m00082.AA SLK 13-152 23 3.6e-13 40.68 In-house 1-143 (259) Show / Hide 
Range on Protein: 13-152
Range on HMM: 1-143/259
Sequence Identity: 23% (33 aa)

YKLISEIGSGKFSHCYLCKSIKYELEFVAKVIPGCSDD--IQNVLEMEVQSKLAHSNIVNIYDKFIEFNYCVLILEYCNNGNLSS-LFKLSKESDPFVIQ
...| |.| | |   |  ..   ..   ||.|   ...     . |... |.. | |||..|. .   |   ...|.|. | . . .  | .      ||
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKDEEELEDYMVEIDILSECKHPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIMVELEHPLTEDQIQ

CIACQILDVLAFAHDEGMQHFGLNPNNIFVDKFNIVKISDFGI
 .. .... | . |.. . |  |   || .     |.. |||.
YVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGV
Kinase 93576.m00082.AA ULK 13-151 21 5.3e-13 41.81 In-house 1-187 (329) Show / Hide 
Range on Protein: 13-151
Range on HMM: 1-187/329
Sequence Identity: 21% (41 aa)

YKLISEIGSGKFSHCYLCKSIKYEL------EFVAKVIP--GCSDDIQN----------VLEMEVQSKLA--------HSNIVNIYDKFIEF--NYCVLI
| |. ..|.| |   . .| .. .        ...|.|.   .. . ..            | ... ||         | |||  || | .   |.. .|
YCLNHCLGKGSFG--KVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYII

LEYCNNGNLSSLFK----------LSKESDPFVIQCIACQILDVLAFAHDEGMQHFGLNPNNIFVDKFN------------IVKISDFG
.|||| |.|... |            |      .. . .|||  . . |...  |  . | || ... .            ..||.|||
MEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFG
Kinase 93576.m00082.AA S_TKc 13-190 18 1e-12 9.73 SMART 1-231 (231) Show / Hide 
Range on Protein: 13-190
Range on HMM: 1-231/231
Sequence Identity: 18% (47 aa)

YKLISEIGSGKFSHCYLCKSIKYELEFVAKVIPGCSDDIQNVLEMEVQSKLAHSNIVNIYDKFIEFNYCVLILEYCNN--GNLSSLFKLSKE------SD
|... .||.| |. .|.|. .|   ..  |.|.     ..   |... .|  | |||..|| | . ..  ...|||..  |.| .. |  .        .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

PFVIQCIACQILDVLAFAHDEGMQHFGLNPNNIFVDKFNIVKISDFGIDQILSLNSTSYQHNRPIEYLAPEIFTNIPL----------------------
. .......||.. |.. |. |  |  | | ||..|.   .||.|||.  .|    |..      .|.|||..                           
E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCG--TPWYMAPEVL-GYGKCKCDWWSCGCILYEMLCGYPPF

---------------------------------QSRK-------DQFL
                                 .  .       ....
PQMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase 93576.m00082.AA MLCK 13-87 32 2.6e-12 28.22 In-house 1-77 (257) Show / Hide 
Range on Protein: 13-87
Range on HMM: 1-77/257
Sequence Identity: 32% (25 aa)

YKLISEIGSGKFSHCYLCKSIKYELEFVAKVIPG-CSDDIQNVL-EMEVQSKLAHSNIVNIYDKFIEFNYCVLILEY
|  ..|.| |||.  . |   .  ....||.|.   . | .||. | |.  .| | |.....| | . | .|.|.||
YQIHEELGRGKFGIVHRCIEKSTGKTWAAKFIKCRKPKDKENVKNEIEIMNQLHHPNLIQCHDAFETKNEMVMIMEY
Kinase 93576.m00082.AA Ciliate-E1 19-164 19 5.3e-12 35.78 In-house 1-167 (202) Show / Hide 
Range on Protein: 19-164
Range on HMM: 1-167/202
Sequence Identity: 19% (33 aa)

IGSGKFSHCYLCKSIKYE----LEFVAKVIPG-CSDDIQNVLEMEV--QSKLA-HSNIVNIYDKFI-EFN-YCVLILEYCNNGNLSSLF---------KL
||.| ||  .  |....      . . ...    ....|.... .   .. .  . .|..|.| .. ..|  |..|.|.|.   .  |.         ..
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQC

SKESDPFVIQ---CIACQILDVLAFAHDEGMQHFGLNPNNIFVDKFNIVKISDFGIDQILSLNSTSYQ
...   | .|   .|..|..| |.  |. .  |. ..| || ...... ...|||| ..| .|.....
QQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQC
Kinase 93576.m00082.AA TyrKc 13-190 12 4e-06 -123.08 SMART 1-280 (280) Show / Hide 
Range on Protein: 13-190
Range on HMM: 1-280/280
Sequence Identity: 12% (38 aa)

YKLISEIGSGKFSHCYLCKSIKYELEFVAKVIPGCSDDIQNVL-EMEVQSKL--AHSNIVNIYDKFIEF-------NYCVLILEYCNNGNLSSLFKLSKE
 .|. ..|.| |   |... .   ..   |..  ..  ..  . |... .||   | |||..|   ..            ...||. .|.| .  . ...
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

SDPFVIQCIACQILDVLAFAHD--EGMQHFGLNP--------NNIFVDKFNIVKISDFGIDQILSLN------STSY------QHN--RPIEYLAPEIF-
           .  | | |...  .||..   ..         |. |.. ..|||||||    .         .  |      . .   ||  .||| . 
K---------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

----------------------------TN-----IP-------------LQSRKD-----------------------------------QFL
                             .     ..             .   ..                                   ...
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 93576.m00082.AA MLCK 113-151 31 0.000169 7.21 In-house 104-144 (257) Show / Hide 
Range on Protein: 113-151
Range on HMM: 104-144/257
Sequence Identity: 31% (13 aa)

CQILDVLAFAHDEGMQHFGLNPNNI-FVD-KFNIVKISDFG
.||.. ... |. .  |. |.| || ... . . .|| |||
RQICEGVHHMHWQNIVHLDLKPENIMCQTRTSHQIKIIDFG