Gene 87361.m00117 (T.vaginalis)

87361.m00117

Species: T.vaginalis
Alias: TvagK0062, 87361.m00117
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
87361.m00117.AA Protein None 322 None Fasta, JSON
87361.m00117.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of 87361.m00117.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 87361.m00117.AA CAMKL 10-262 35 2.8e-100 320.74 In-house 1-297 (297) Show / Hide 
Range on Protein: 10-262
Range on HMM: 1-297/297
Sequence Identity: 35% (108 aa)

YKPLHLIGLGAFAKVYLAVDTRT-LEKCAVKVIP--KINPEDRTDQTKR---------IKNEIEIHKVLR---HPFIVQLYDVIETPEN------FYLIM
|. .  .| |.|.|| ||...||  || |.|.|   ||. .. ... |.         |. ||.|.| |.   || |..||.||||||.      .||.|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYVDGCS--LIDDVNTN----GLYTESEAANIFAQIIIALEYLHSKHNLIHRDLKAENIMITHNK--LVKIIDFGLS-----C-RSNSKDVSERCGSLSY
||..| .  | | .  .    |  .|.||  .| ||. |..|.||..  .|||.|.|||....|.   .||||||.|     |   . .  ...|||..|
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHG-IVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

ASPEIVLG--KKYT-TSHDIWSCGIVLYAIVCGHIPFEDE-------EVQIHMFNILNQEVEIPD---TISPELESLIRGMLEKFFKNRFRLDQIINQPW
..|||..|  |.|     ||||||..|||.|||. ||.|.       . .  .... ..  . |.    .| ....|||.||..  . |. ..|| | ||
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

L
.
M
Kinase 87361.m00117.AA CAMK 15-262 22 1.1e-98 318.58 In-house 1-425 (425) Show / Hide 
Range on Protein: 15-262
Range on HMM: 1-425/425
Sequence Identity: 22% (96 aa)

LIGLGAFAKVYLAVDTRTL------------EKCAVKVIPK----------------INPEDRTD--------QTKRIKNEIEIHKV-------LRHPFI
 .| |.|.||.|.....|             .|.|.|.|.|                |. .   .          |....||||.|        |.|| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQLYDVIE------------TPEN--------FYLIM---EYVDGC----SLIDDVNTNGL---------------YTESEAANIFAQIIIALEYLHSKH
..||.|.|            | ..        .|..|   ||..|      | | .  .|                .||.||. .| ||. |..|.||..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

NLIHRDLKAENIMITHNK-----------------LVKIIDFGLSCRSNSKD-------------------------VSERCGSLSYAS-PEIVLGKK--
  .||||| |||....|.                  .||||||.... ....                          ...||...|.. ||...||.  
-IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

------------YTTSHDIWSCGIVLYAIVCGHIPFEDE-------------EVQIHMFNILNQEVE-IPDT---------------ISPE--------L
            |. . |.||||..||. .||. ||...             . .  . .|.. . . .|.                || |         
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC

ESLIRGMLEKFFKNRFRLDQIINQPWL
 .|||.||..  ..|. ..|. | ||.
KDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 87361.m00117.AA MARK 10-262 39 1.5e-91 299.55 In-house 1-262 (262) Show / Hide 
Range on Protein: 10-262
Range on HMM: 1-262/262
Sequence Identity: 39% (106 aa)

YKPLHLIGLGAFAKVYLAVDTRTLEKCAVKVIPKINPEDRTD-QT-KRIKNEIEIHKVLRHPFIVQLYDVIE--TPEN-FYLIMEYVDGCSLIDDVNTN-
|| |  || |..|||.||....| .| |.|...|   .. .| |. | .. ||||.| | || |..|..|||  |... .||||||. | .| | .    
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEK---FKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHP

-GLYTESEAANIFAQIIIALEYLHSKHNLIHRDLKAENIMITHNK--LVKIIDFGLSCRSNSKD-VSERCGSLSYASPEIVLGKKYT-TSHDIWSCGIVL
 |  .|.||  || ||. |..|.|||.  .|||.|.|||.| .|.   .||||||.| . ..    .. ||...|..|||.|.|.|. .  ||||.|.||
NGRLHEEEARRIFRQIVSAVNYCHSKN-IVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVL

YAIVCGHIPFE--DEEVQIHMFNILNQEVEIPDTISPELESLIRGMLEKFFKNRFRLDQIINQPWL
|..|||. ||.  . .    ...||. . .||. .|.|...||. .|    . |  ...| . ||.
YFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 87361.m00117.AA S_TKc 10-262 33 2.2e-90 307.51 SMART 1-231 (231) Show / Hide 
Range on Protein: 10-262
Range on HMM: 1-231/231
Sequence Identity: 33% (90 aa)

YKPLHLIGLGAFAKVYLAVDTRTLEKCAVKVIPKINPEDRTDQTKRIKNEIEIHKVLRHPFIVQLYDVIETPENFYLIMEYVDG--CSLIDDVNTNGL--
|. | .|| |||.|||......| ...|.|.|.           ..|..||.|.|  .||.||.||||... ...|..|||.||   .| |    .|   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----YTESEAANIFAQIIIALEYLHSKHNLIHRDLKAENIMITHNKLVKIIDFGLSCRSNSKDVSERCGSLSYASPEIVLGKKYTT-SHDIWSCGIVLYA
    ..| .|. ...||. ||||.||. . |||||| |||....   .||.||||...      .  ||.. | .||..   .|.. . |.||||..|| 
LRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

IVCGHIPFEDEEVQIHMFNILNQEVEIPDTISPELESLIRGMLEKFFKNRFRLDQIIN-------QPWL
 .||  ||.    .  ||...          |||. ..||..|.|  ..|    .. .        ||.
MLCGYPPFP---QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 87361.m00117.AA AMPK 10-262 42 3e-90 268.12 In-house 1-254 (254) Show / Hide 
Range on Protein: 10-262
Range on HMM: 1-254/254
Sequence Identity: 42% (110 aa)

YKPLHLIGLGAFAKVYLAVDTRTLEKCAVKVIPKINPEDRTDQTKRIKNEIEIHKVLRHPFIVQLYDVI-ETPENFYLIMEYVDGCSLIDDVNTNGLYTE
|     || |.| || ... ..| || |.|.. |    | ... .||..||.| |..||| |.|||.|| |||. ....|||| |  | | .  .|  .|
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMV-ERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQE

SEAANIFAQIIIALEYLHSKHNLIHRDLKAENIMITHNKLVKIIDFGLS--CRSNSKDVSERCGSLSYASPEIVLGKKYTTSH-DIWSCGIVLYAIVCGH
 ||.  |.||| ..||.| .|.  ||||| ||. . ||| .|| |||||  .  . .  .  |||  ||.||.. ||.|     ||||||..||| .|| 
REACRFFQQIISGVEYCH-RHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDG-EFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGY

IPFEDEEVQIHMFNILNQEVEIPDTISPELESLIRGMLEKFFKNRFRLDQIINQPWL
 ||.||..     .|.|.|..||. .||| ..||..||..   .|.  ..| | ||.
LPFDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 87361.m00117.AA Pkinase 10-262 31 1.2e-78 272.35 Pfam 1-293 (293) Show / Hide 
Range on Protein: 10-262
Range on HMM: 1-293/293
Sequence Identity: 31% (94 aa)

YKPLHLIGLGAFAKVYLAVDTRTLEKCAVKVIPKINPEDRTDQTKR-IKNEIEIHKVLRHPFIVQLYDVIETPENFYLIMEYVDGC----SLIDDVN--T
|. .  || |.|..||....  | .. |||.|.| . ..  |||.| . .||.|.| |.||.||.|||. |.. . |..|||..|     .| | .    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

NGLY--TESEAANIFAQIIIALEYLHSKHNLIHRDLKAENIMITHNKLV----KIIDFGLSC---RSNSKDVSERCGSLSYASPEIVL-GKKYTTSHDIW
.| .  .| |. ... ||. .|||.|| .. |||||| |||.| .|  .    ||.||||..     |.   . .||.. |..||... |..|... |.|
HGCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SCGIVLYAIVCGHIPFEDE------EVQIHMFNILNQEVEIPDTIS---------------------PELESLIRGMLEKFFKNRFRLDQIINQPWL
|||..||  .||. || ..      . .  ...|.  ... .   .                     .|. ..|...|.|  | |   .|| . ||.
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 87361.m00117.AA ULK 10-262 30 1.5e-69 237.4 In-house 1-329 (329) Show / Hide 
Range on Protein: 10-262
Range on HMM: 1-329/329
Sequence Identity: 30% (99 aa)

YKPLHLIGLGAFAKVYLAVDTRT----LEKCAVKVIP----KINPEDRT--DQTKRIKNEIEIHKVLR--------HPFIVQLYDVIETP--ENFYLIME
|   | .| |.|.||| . . .|     ||.|.|.|.    .... ...   . . .||||.| | |         || ||.|||. ||.   |.|.|||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YVDGCSLIDDVNTNGL----------YTESEAANIFAQIIIALEYLHSKHNLIHRDLKAENIMITHNK------------LVKIIDFGLSCRSNSK----
| .|  | .  ..|.            .|.|| ..| ||. .. .|| ||| ||||.| .||.|. ..             .|| |||..   ..     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELH-KHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQ

--DVSER-----CGSLSYASPEIVL----GKKYTTS-HDIWSCGIVLYAIVCGHIP----FEDEEVQIHMFN----------ILNQEVEIP-----DTIS
   ..       ||.  | .|.|.     .|.|...  |||| |...| .. |  |    |.|.  ||.. .          | .|  ..|     ..||
QMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

PELESLIRGMLEKFFKNRFRLDQIINQPWL
||...|||.||..  | |.  ....| ||.
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 87361.m00117.AA ULK 10-262 30 1.5e-68 234.01 In-house 1-324 (324) Show / Hide 
Range on Protein: 10-262
Range on HMM: 1-324/324
Sequence Identity: 30% (99 aa)

YKPLHLIGLGAFA-KVYLAVDTRT---LEKCAVKVIP--KINPEDRTDQ----TKRIKNEIEIHKVLR---HPF--IVQLYDVIETP--ENFYLIMEYVD
|   | .| |.|. ||| . . .|    .. |.|.|.  |.|     ..     . .||||.| | |    ||.  ||.|||. ||.   |.|.|||| .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GCSLIDDVNTNGL---------YTESEAANIFAQIIIALEYLHSKHNLIHRDLKAENIMITHNK------------LVKIIDFGLSCRSNS-KDVSERC-
|  | .  ..|.           .|.|| ..| ||. .. .|| ||| ||||.| .||.|....             .|| |||..   ..       | 
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELH-KHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

---------GSLSYASPEIVL----GKKYTTS-HDIWSCGIVLYAIVCGHIPFEDE-EVQIH------------MFNILNQEVEIPD-----TISPELES
         |.  | .|.|.     .|.|...  |||| |...| .. |  ||.   . |..            .. | || ...|.      ||||...
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LIRGMLEKFFKNRFRLDQIINQPWL
|||.||..  | |.  ..|.| ||.
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 87361.m00117.AA Ciliate-E2 10-262 25 5.8e-68 232.09 In-house 1-365 (365) Show / Hide 
Range on Protein: 10-262
Range on HMM: 1-365/365
Sequence Identity: 25% (97 aa)

YKPLHLIGLGAFAKVYLA--VDTRTLE----------------KCAVKVIP-KINPEDRTDQTKRIKNEI-EIH------------KVLRHPFIVQLYDV
|| . .|| |.|..||..    .. ..                |...| .  ||. ..   |.|...... ||.            . | ||.|...|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

IE--TPENFYLIMEYVDGCSLID-----DVNTNGL------YTESEAANIFAQII---------------IALEYLHSKHNLIHRDLKAENIMITHNKLV
 .  . .|.||.|||..| .| |     . . |        .|| |...|..||.                ||||||||.| ||||.| |||..     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIIDFGLSCRSNSKDVSER---------------------------------CGSLSYASPEIVLGKK---------YTTSHDIWSCGIVLYAIVCGHIP
|||||||| . . .   ..                                 ||.. | .|||. |||         |... ||||.|..||  ..|  |
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FEDEEVQIHMFNILNQEVEIP------------------DTISPELESLIRG----MLEKFFKNRFR-LDQIINQPWL
|        . .|.......|                  . .|.|   ||.     ||.|  ..|.   .||.| ||.
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 87361.m00117.AA Ciliate-E2-Unclassified 10-262 26 2.4e-64 220.11 In-house 1-352 (352) Show / Hide 
Range on Protein: 10-262
Range on HMM: 1-352/352
Sequence Identity: 26% (93 aa)

YKPLHLIGLGAFAKVYLAVDTRTLEKCAVKVIPKINPED-RTDQTK----RIKNEIEIHK----------------VLRHPFIVQLYDVIETPENFYLIM
|| .. || |.|.|||....  . .. | | . ||.  . .  ..|    ....|....|                 . ||||| .... .. .|.|..|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYVDGCSLIDDVNTN-----------------GLYTESEAA-----NIFAQIIIALEYLHSKHNLIHRDLKAENIMITHNK---LVKIIDFGLSCRSN--
||..| .|..  . .                    || .|.     ..||||. .|||||.|.| ||||.| |||... |.    .||||||.| ...  
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

---------------SKDVSERCGSLSYA----SPEIVLGKKYTTS----HDIWSCGIVLYAIVCGHIPFEDEEVQIH---------------MFNIL-N
               ..  . .||...|     .||.  |..| .|     ||||.|..||... |  ||.|.   .|               ....  .
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

QEVE--------IPDTISPELESLIR----GMLEKFFKNRFRLDQIINQPWL
....        ||...||| . .|.     ||.|  ..|  ..||.| ||.
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 87361.m00117.AA QIK 10-262 35 1.4e-63 217.55 In-house 1-272 (272) Show / Hide 
Range on Protein: 10-262
Range on HMM: 1-272/272
Sequence Identity: 35% (97 aa)

YKPLHLIGLGAFAKVYLAVDTRTLEKCAVKVIPKINPEDRTDQTKRIKNEIEIHKVLRHPFIVQLYDVIETPENFYLIMEYVDGCSLIDDVNTNGL----
|     || | || | ||    | .| |.|.| |   .   .  .... |..| |.|.||.|. ||.|.|| .  |...||  .  . | .. .|.    
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDE--ENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVK

----------------YTESEAANIFAQIIIALEYLHSKHNLIHRDLKAENIMITHNKLVKIIDFGLSCRSNSKD-VSERCGSLSYASPEIVLGKKYT-T
                 .|.||. .| ||. | .|.| |.| .|||||||||..  |  .||.|||.|  . .    .  |||  || ||. .||.|.  
MVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCH-KRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGP

SHDIWSCGIVLYAIVCGHIPFEDEEVQIHMFNILNQEVEIPDTISPELESLIRGMLEKFFKNRFRLDQIINQPWL
  |||| |.|||. ||| .||  . .|     .|   . ||  .| ..|.||| ||    . |.  .||.. .|.
KVDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase 87361.m00117.AA MELK 10-262 36 1.1e-61 209.54 In-house 1-254 (254) Show / Hide 
Range on Protein: 10-262
Range on HMM: 1-254/254
Sequence Identity: 36% (94 aa)

YKPLHLIGLGAFAKVYLAVDTRTLEKCAVKVIPKINPEDRTDQTKRIKNEIEIHKVLRHPFIVQLYDVIETPENFYLIMEYVDGCSLIDDVNTNGLYTES
|.  . || | |||| ||.   | .. |.|.. |   .   .   |.| |..  | |||  | ||| .||| . ....|||  |  . | .  .    |.
YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDK---NQLGHDLPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEE

EAANIFAQIIIALEYLHSKHNLIHRDLKAENIMITHNKLVKIIDFGLSCRSNSKDVSE----RCGSLSYASPEIVLGKKYTTSH-DIWSCGIVLYAIVCG
|.  .| ||. |. |.||.    ||||| ||.... .. .|.|||||  ..  .         |||. || ||.. ||.|  |  |.|| ||.||...||
ETRHFFRQIVSAIAYVHSQ-GYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCG

HIPFEDEEVQIHMFNILNQEVEIPDTISPELESLIRGMLEKFFKNRFRLDQIINQPWL
 .||.|. ..|    |.    | |. .|||   |.| ||    | | .. ...| ||.
FLPFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase 87361.m00117.AA TyrKc 10-260 23 2.4e-16 41.47 SMART 1-280 (280) Show / Hide 
Range on Protein: 10-260
Range on HMM: 1-280/280
Sequence Identity: 23% (69 aa)

YKPLHLIGLGAFAKVYLAVDTRTLEKCAVKVIPKINPEDRTDQTKRIKNEIEIHKVL--RHPFIVQLYDVIETP-------ENFYLIMEYVDGCSLIDDV
 . .. .| ||| .||... .   ...|||.. .          . . .|..| . |  .|| ||.|| |. ..       |  ...|||... .| |  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

NTNGL-YTESEAANIFAQIIIALEYLHSKHNLIHRDLKAENIMITHNKLVKIIDFGLSCRSNSK--------DVSER---CGS--LSYA--SPEIVLGKK
  ..   . ..  ..  ||    |||||| |.||||| | |.....|. ||| |||||    ..          . .   .|   | .   .||    .|
RKHRPKLCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YTTSHDIWSCGIVLYAIV-CGHIPFEDE----EVQIHMFNILNQE--VEIPDT--------ISPELESLIRGMLEKFFKNRFRLDQIINQP
.||  |.|| |.... |   |  | ...       ..... . |    ..|.          ..|. ....   .   ..| .  .|. . 
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 87361.m00117.AA Pkinase_Tyr 121-157 56 9.7e-09 30.23 Pfam 123-158 (270) Show / Hide 
Range on Protein: 121-157
Range on HMM: 123-158/270
Sequence Identity: 56% (21 aa)

ALEYLHSKHNLIHRDLKAENIMITHNKLVKIIDFGLS
..|||.||. .||||| | |...|.|. ||| ||||.
GMEYLESKN-CIHRDLAARNCLVTENNVVKICDFGLA
Kinase 87361.m00117.AA Pkinase_Tyr 10-93 29 3.7e-07 24.86 Pfam 1-91 (270) Show / Hide 
Range on Protein: 10-93
Range on HMM: 1-91/270
Sequence Identity: 29% (28 aa)

YKPLHLIGLGAFAKVYLAVDT----RTLEKCAVKVIPKINPEDRTDQ---TKRIKNEIEIHKVL-RHPFIVQLYDVIE-TPEN--FYLIMEYVDG
 . .. .| ||| .||... .     |  ..|||.. |   |. ...    .   .|..| | | .|| ||.|| |.    |    |..|||. .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-K---EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPH