Gene 80364.m00040 (T.vaginalis)

80364.m00040

Species: T.vaginalis
Alias: TvagK0768, 80364.m00040
External Links:
Annotation:

Classification

Group: Other
Family: PLK
Subfamily: PLK1

Sequence

Name Sequence Type Origin Length Description Download
80364.m00040.AA Protein None 521 None Fasta, JSON
80364.m00040.kin_dom Protein Kinase Domain None 257 None Fasta, JSON

Protein domain

Protein domains of 80364.m00040.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 80364.m00040.AA PLK 22-278 46 1.9e-126 413.74 In-house 1-258 (258) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-258/258
Sequence Identity: 46% (119 aa)

YKRQEELGRGGFATVYRVVEQSSGKEYAMKVVPKERISKPKAIEKMKSEIAIQASLNHPNILRSYAAFEDATNHYIVTELCPGHSVRDLVKKA-GHLSEL
|.|.. ||.|||| .|.. . .....|| |||||... ||.. ||||.||.|. .|.||||.. .  |||. | ||| |.|...|  .. |.   .|.| 
YERGHFLGKGGFAKCYEMTDIHTKQVYAIKVVPKSLMQKPHQREKMKQEIEIHRQLHHPNIVKFHHFFEDHENVYIVLEYCHNRSLMHYHKRRAKRLTEP

ESSKIMKDVLEGLAYLHDNRVIHRDLKLENFLVGKDGRIKIADFGLSAKLDYDDERKFTVCGTPNYLSPEILTSASKGHSYEVDIWAIGVCAYAMLVGRP
|   .|  . .|| |||..|.||||||| |..  .. ..||.||||...|.||.||| |.|||||| .||.|    .|||||||.|..|.  |..|.|.|
EVRYYMYQIVQGLKYLHQHRIIHRDLKLGNLFLNDNMHVKIGDFGLATRLEYDGERKKTMCGTPNYIAPEVLDGNKQGHSYEVDCWSLGCIMYTLLIGKP

PFETARTKLTYEHIKTCSYHFPVEPRLSHIAKDFIQSTLQIKPELRPNAQELLVHQFI
||||.. | ||. || . |.|| .. .|. |||.||. |.  |. ||.. ..| |.| 
PFETKDVKETYKRIKHNHYSFPEHCPISDEAKDLIQKMLNWNPDERPTIDQILQHPFF
Kinase 80364.m00040.AA PLK-Unclassified 22-278 43 2.5e-114 386.12 In-house 1-264 (264) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-264/264
Sequence Identity: 43% (114 aa)

YKRQEELGRGGFATVYRVVEQSSGKEYAMKVVPKERISKPKAIEKMKSEIAIQASLNHPNILRSYAAFEDATNHYIVTELCPGHSVRDLVKKA-------
|.| . || |||| .| | . .. |.|| |..||  . | .| .| .||| |. ||.|.|| . .  |||  | ||. |.||.... .. |.        
YHRGHFLGKGGFAKCYQVKNIETKKIYAAKIIPKSSLTKNRARQKLISEIKIHKSLHHKNIVKFEHCFEDHENVYILLEYCPNGTLMEYIKRRNFQLFEK

GHLSELESSKIMKDVLEGLAYLHDNRVIHRDLKLENFLVGKDGRIKIADFGLSAKLDYDDERKFTVCGTPNYLSPEILTSASKGHSYEVDIWAIGVCAYA
  |.|.|   .   ....| |||.||.||||||| | ... . ..||.||||..|| .| |.| |.|||||| .||||    .|||||||.|..|. .|.
KRLTEYEVKCYTYQIVQALKYLHQNRIIHRDLKLGNIFLNDNMEVKICDFGLATKLENDGEKKKTICGTPNYIAPEILDGKHQGHSYEVDCWSFGCILYT

MLVGRPPFETARTKLTYEHIKTCSYHFPVEPRLSHIAKDFIQSTLQIKPELRPNAQELLVHQFI
.|.|.|||||   | ||. ||. .| || .. .|. |||.||. |.. |. ||.  ... | | 
LLIGKPPFETKDVKQTYKKIKCNQYSFPEPCHISDNAKDLIQHILNWNPDQRPTIDQIMMHPFY
Kinase 80364.m00040.AA AGC 22-278 22 5.5e-103 266.52 In-house 1-395 (395) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-395/395
Sequence Identity: 22% (92 aa)

YKRQEELGRGGFATVYRVVEQ------SSGKEYAMKVVPKER-ISKPK--AIEKMKSE------------IAIQASLN----------HPNILR-SYAAF
..    .|.|.| .|| | .       ..|| |||||. |.. | . |   .|. ..|              | . .|          ||.| .  . .|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

EDATN--HYIVTELCP----------G-HSVRDLVK--KAGHLSELESSKIMKD-------VLEGLAYLHD-NRVIHRD-LKLENFLVGKDGRIKIADFG
.| ..   |.| |..|          |  .   | .  | |...| ..  ..         .. .| |||. . .|||| ||.|| |  .|| ||..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSAKLDYDD--------------------------------------------------ERKFTVCG--TPNYLSPEILTSASKGHSYEVDIWA--IGVC
|. ..  |.                                                  .|  | ||  ||.|..||||      .....|.|.   |..
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL------YGKACDWWSFGLGCL

AYAMLVGRPPFETAR----------TKLTYEHIK------TCSYHFP--------VEPRLSHIAKDFIQSTLQIKPELRPN----------AQELLVHQF
 | ||.|.|||               . ... |.      ..  .||         .. .|  |||.|.  |.  || |.           |.|.  | .
MYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPW

I
 
F
Kinase 80364.m00040.AA CAMK 27-278 20 1e-98 318.73 In-house 1-425 (425) Show / Hide 
Range on Protein: 27-278
Range on HMM: 1-425/425
Sequence Identity: 20% (85 aa)

ELGRGGFATVYRVVEQSSG------------KEYAMKVVPKERISK-------------------------PKAIEKMKSEIAIQAS-------LNHPNI
.||||.|..|..... ...            ...|.|...|.....                         ||  .....||.|  .       |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LRSYAAFEDATN-------------------HYIVT---ELCPGH----SVRDLVKKAGH---------------LSELESSKIMKDVLEGLAYLHDNRV
.. | ..||...                    |.|.   |.|.|      . | ... |.               ..| | ..... ......|.|.. .
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDLKLENFLVGKD-----------------GRIKIADFGLSAKLDY-----------------------DDERKFTVCGTPNYLS-PEILTSA-----
.|||||.|| |. ..                 . |||.|||...|.|                        ...   |.|||| | . ||.| .      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------SKGHSYEVDIWAIGVCAYAMLVGRPPFETA-------------RTKLTYEHIKTCSYHFPVEP----------------------RLSHIAKD
        .......|.|..||  |.||.|.|||.                 . ..| |... |.|| ..                       .|  .||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

FIQSTLQIKPELRPNAQELLVHQFI
.|.. ||  || |..... | |...
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 80364.m00040.AA S_TKc 22-278 32 4.8e-97 329.61 SMART 1-231 (231) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-231/231
Sequence Identity: 32% (88 aa)

YKRQEELGRGGFATVYRVVEQSSGKEYAMKVVPKERISKPKAIEKMKSEIAIQASLNHPNILRSYAAFEDATNHYIVTELCPG--HSVRDLVKKAGH---
|.  ...|.|.|..||.... ..|...|.|...          |....||.|  . .|||| . | .|.| .. |.|.|.|.|   ...|. || |.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LSELESSKIMKDVLEGLAYLHDNRVIHRDLKLENFLVGKDGRIKIADFGLSAKLDYDDERKFTVCGTPNYLSPEILTSASKGHSY-EVDIWAIGVCA
   ..| .  ..|. ....|.|.|....|||||| || |. .  .|||.||||...|        |.||||.|..||.|     |... ..|.|..|.. 
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCIL

YAMLVGRPPFETARTKLTYEHIKTCSYHFPVEPRLSHIAKDFIQSTLQIKPELRPNAQELLV-------HQFI
| ||.|.|||.    ......|.            |. |||||.  ||  || || | |.|        |...
YEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 80364.m00040.AA PLK1 22-278 42 3.1e-92 303.49 In-house 1-253 (253) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-253/253
Sequence Identity: 42% (110 aa)

YKRQEELGRGGFATVYRVVEQSSGKEYAMKVVPKERISKPKAIEKMKSEIAIQASLNHPNILRSYAAFEDATNHYIVTELCPGHSVRDLVKKAGHLSELE
|.. . ||.||||  | . ...  . .| |||||. . |... .||  || |  .|.|..| . .  |||  | ||| |||  .|. .| |. . . | |
YEKGRFLGKGGFAHCYEIRDKDTKEVFAGKVVPKSLLIKQHQRDKMTQEIQIHRQLHHRHIVKFHHFFEDKQNVYIVLELCRRRSLMELHKRRKAITEPE

SSKIMKDVLEGLAYLHDNRVIHRDLKLENFLVGKDGRIKIADFGLSAKLDYDDERKFTVCGTPNYLSPEILTSASKGHSYEVDIWAIGVCAYAMLVGRPP
.   |. ..||  |||.|..||||||| |  .  . ..|| ||||  |..|| ||| | ||||||. ||.|.   ||||.|||||.||   | .|.|.||
CRYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGDFGLATKCEYDGERKKTLCGTPNYIAPEVLN--KKGHSFEVDIWSIGCIMYILLFGQPP

FETARTKLTYEHIKTCSYHFPVEPRLSHIAKDFIQSTLQIKPELRPNAQELLVHQFI
||| . | || .|| . |  | .  .|. |...|.. |. .|. ||.....|  .|.
FETKCLKETYSRIKKNEYRIPSH--ISQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF
Kinase 80364.m00040.AA Pkinase 22-278 32 1.2e-90 312.22 Pfam 1-293 (293) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-293/293
Sequence Identity: 32% (95 aa)

YKRQEELGRGGFATVYRVVEQSSGKEYAMKVVPKERISKPKAIEKMK-SEIAIQASLNHPNILRSYAAFEDATNHYIVTELCPGH----SVRDLVK--KA
|.. . .|.|.|..||. .....||..|.|...|..... | ... . |||.| ..||||||.| | .||| .. |.|.|.|.|     .  |...  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GHL--SELESSKIMKDVLEGLAYLHDNRVIHRDLKLENFLVGKDGRI----KIADFGLSAKL-DYDDERKFTVCGTPNYLSPEILTSASKGHSYEVDIWA
| .  || |  ..|. .|.||.|.|....||||||.||.|. ..| |    ||.||||....    ..   |.||||.|..||..   .......||.|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-GGQYYGPKVDMWS

IGVCAYAMLVGRPPFETA------RTKLTYEHIKTCSYHFPVEPRLS-------------------HIAKDFIQSTLQIKPELRPNAQELLVHQFI
.|.  | || |||||  .      . .  .. |. . .||. .   |                     .|||| . |. .|. ||.|...| | ..
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 80364.m00040.AA CAMKL 22-278 28 1.4e-86 276.32 In-house 1-297 (297) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-297/297
Sequence Identity: 28% (85 aa)

YKRQEELGRGGFATVYRVVE-QSSGKEYAMKVVPKERISKPKAIEKM------------KSEIAIQASLN---HPNILRSYAAFEDATN------HYIVT
|.  ..||.|.|..|   .  .  |...|.|.. |..|..   ..|.            . ||.|. .||   |||| . |  .|. ..       |.|.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELCPGHS--VRDLVKKAGH----LSELESSKIMKDVLEGLAYLHDNRVIHRDLKLENFLVGKDG--RIKIADFGLSAKLD-Y---DDERKFTVCGTPNYL
|.|.| .    | ..| ||    ..| |  .. . ......|.|.....|||.|.|| |. ..|   |||.|||.|.. . .   ...   | ||.|.| 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

SPEILTS-ASKGHSYEVDIWAIGVCAYAMLVGRPPFETA--------RTKLTYEHIKTCSYHFPVEPRLSHIAKDFIQSTLQIKPELRPNAQELLVHQFI
.|||. .   . . ..||||..||  |||..|. ||. .         . . |. |... |..|. ...|  ..|.|.. || .|| ||...... | . 
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 80364.m00040.AA PLK2 22-278 42 4.7e-85 273.81 In-house 1-257 (257) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-257/257
Sequence Identity: 42% (110 aa)

YKRQEELGRGGFATVYRVVEQSSGKEYAMKVVPKERISKPKAIEKMKSEIAIQASLNHPNILRSYAAFEDATNHYIVTELCPG----HSVRDLVKKAGHL
| |   || ||||  |     .... ||.|.||..|..||.  |||  ||.. . | |..| . .. |||. | ||. |.|       |     |   ||
YCRGKLLGKGGFARCYEMTDMDTHYVYAVKIVPHSRVAKPHQREKMEREIELHRQLRHRHIVQFHHHFEDRDNIYILLEYCSRQVPLKSMAHMWKVRHHL

SELESSKIMKDVLEGLAYLHDNRVIHRDLKLENFLVGKDGRIKIADFGLSAKLDYDDERKFTVCGTPNYLSPEILTSASKGHSYEVDIWAIGVCAYAMLV
 | |    |. ...|| |||. ..||||||| || . .   .|| |||| |.|    ... | ||||||..||.|    .||| | |||| |   | ||.
TEPEVRYYMRQIVSGLRYLHQQCIIHRDLKLGNFFINDNMEVKIGDFGLAARLEPEEHCHRTMCGTPNYIAPEVL--NRQGHSCESDIWALGCIMYTMLC

GRPPFETARTKLTYEHIKTCSYHFPVEPRLSHIAKDFIQSTLQIKPELRPNAQELLVHQFI
||||||||  | ||  |.   ||.|    ||  |.  | . |   || ||   ... | | 
GRPPFETANLKETYRCIRHNHYHMPTH--LSPPARHLIARMLSPDPEDRPSLDHIIRHDFF
Kinase 80364.m00040.AA Ciliate-E2 22-278 27 1.7e-83 283.7 In-house 1-365 (365) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-365/365
Sequence Identity: 27% (104 aa)

YKRQEELGRGGFATVYRVVE-----------------------QSSGKEYAMKVV-PKERISKPKAIEKMK---------SEIAIQASLNHPNILRSYAA
|| .. .|.|.|..||..                         .  .|.||||.. ... ... . |  |.          |  |. .||||||.. | .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--DATNHYIVTELCPGHSVRDLVK------------KAGHLSELESSKIMKDVLE---------------GLAYLHDNR-VIHRDLKLENFLVGKDGR
|.  | .| |.|.|.| | . .|. |            . . ..| | ..||| .|.               .| ||| .  .||||.|.|| |.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

IKIADFGLSAKLDYDDE-------RK------------------------FTVCGTPNYLSPEILTSAS-------KGHSYEVDIWAIGVCAYAMLVGRP
|||.||||| |.| | .       .|                        .|.||||.|..|||| . .       ||..|..|||..||. | || |.|
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFETARTKLTYEHIKTCSYHFP----------------VEPRLSHIAKDFIQS----TLQIKPELRPN-AQELLVHQFI
||        .. || | . ||                    .|  .||.|.      || .|| |.. ....| |...
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 80364.m00040.AA Ciliate-E2-Unclassified 22-278 27 7.2e-76 258.37 In-house 1-352 (352) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-352/352
Sequence Identity: 27% (97 aa)

YKRQEELGRGGFATVYRVVEQSSGKEYAMKVVPKERISK-----PKAIEKMKSEIAIQ------------------ASLNHPNILRSYAAFEDATNHYIV
|| .. .|.|||..||.... . .. ||||   | .| |      |  |.| ......                   ...||.|.. . .|.|  | |||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

TELCPGHSVRDLVKKAGH-----------------LSELESS-----KIMKDVLEGLAYLHDN-RVIHRDLKLENFLVGKDG---RIKIADFGLSAKLDY
.|.|.| . ..  || ..                 ..| ...     .... .|.|| ||| .  .||||.|.|| |. ..|   .|||.|||.| |...
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

D---------------DERKFTVCGTPNYL----SPEILTSASKGHS--YEVDIWAIGVCAYAMLVGRPPFE-TARTK---------------LTYEHIK
.               ...  |.||||||.    .||.| .   .||  |..|||. ||..|.|| |..||. . ...                 |. ||
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

TCSYHFPVEP------RLSHIAKDFIQ----STLQIKPELRPNAQELLVHQFI
 . . || .|      ..|  |||||.    . |. .|. |......| |...
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 80364.m00040.AA STE 22-278 21 4.4e-74 252.43 In-house 1-359 (359) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-359/359
Sequence Identity: 21% (80 aa)

YKRQEELGRGGFATVYRVVEQ------SSGKE---------YAMKVVPKERISK--------------PKAIEKMKSEIAIQASLN--HPNILRSYAAFE
....|..|.|.| |||. .        ..|..         .|.|....|. ..              .. ... . || |   .|  |||| . | ...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DA-------TNHYIVTELCPGHSVRDLVKKA--------------GHLSELESSKIMKDVLEG-LAYLHDNRVIHRDLKLENFLVGKDGRIKIADFGLSA
.        .. .|. |...| |..|..|.               ....| . ..| ...|.| |.|||....||||.|  | |.     .|..|||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

KLDYD----------------DERKFTVCGTPNYLSPEILTSA----SKGHSYEVDIWAIGVCAYAMLVGRPPFET-ARTKLTYEHIKT---CS------
.|. .                ...  |..||| . .||...      .||... .||| .| ..  |. |.||. .   ..  .. ..    ..      
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---YHFPVEP--------------------RLSHIAKDFIQSTLQIKPELRPNAQELLV--HQFI
    . |  |                    ..|   ||||.  ||. |. ||.|..||   | ||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 80364.m00040.AA Pkinase_Tyr 22-175 27 4.7e-23 78.7 Pfam 1-165 (270) Show / Hide 
Range on Protein: 22-175
Range on HMM: 1-165/270
Sequence Identity: 27% (47 aa)

YKRQEELGRGGFATVYRVVEQ----SSGKEYAMKVVPKERISKPKA--IEKMKSEIAIQASL-NHPNILRSYAAFE-DATN--HYIVTELCPGHSVRDLV
 .  ..||.| | .||. .      . . . | |.. ||  . ...  .|.. .|..|  .| .||||.| |..   .     .|||.|..|. . .|  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

KK----AGHLSELESSKIMKDVLEGLAYLHDNRVIHRDLKLENFLVGKDGRIKIADFGLSAKLDYDDE
.|     ..|.  .  ..  .. .|..||.... |||||   | ||.... .||.||||.  . |.|.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDD
Kinase 80364.m00040.AA TyrKc 22-277 22 1.8e-19 71.92 SMART 1-280 (280) Show / Hide 
Range on Protein: 22-277
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

YKRQEELGRGGFATVYR-VVEQSSGKEYAMKVVPKERISKPKAIEKMKSEIAIQASL--NHPNILRSYAAFEDA-------TNHYIVTELCPGHSVRDLV
 .  ..||.| | .||. .       . | |.. ..       .| . .|. |  .|  .||||.| |..  .          ..||.|..|. . .|  
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

KKAGH-LSELESSKIMKDVLEGLAYLHDNRVIHRDLKLENFLVGKDGRIKIADFGLSAKLDYD-------DERKFTV--CGTP----NYLSPEILTSASK
.| .. |.  .  ... .. .| .|||....|||||   | |||.....||.||||| ... |       |  . .   .|        ..|| .    .
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYG

GHSYEVDIWAIGVCAYAML-VGRPPFET-----ARTKLTYEHIKTCSYHFPVEP--------RLSHIAKDFIQSTLQIKPELRPNAQELLVHQF
  . . |.|. ||| . ..  | .| .         .  .|..|.  .  . .           . . .  ...  . .|| ||. .|. ...|
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI-HECF
POLO_box 80364.m00040.AA POLO_box 347-383 35 3.8e-08 33.68 Pfam 1-39 (74) Show / Hide 
Range on Protein: 347-383
Range on HMM: 1-39/74
Sequence Identity: 35% (14 aa)

HSEKYGLGYLLIDGTVGAC-FNDLSRMVMDPFEE-FVQY
 . |||..|.| .|||. . ||| ......| .. .|.|
YRTKYGIMYQLSNGTVQVNFFNDHTKIILCPNMKYAVTY
POLO_box 80364.m00040.AA POLO_box 443-470 34 0.001202 17.07 Pfam 1-29 (74) Show / Hide 
Range on Protein: 443-470
Range on HMM: 1-29/74
Sequence Identity: 34% (10 aa)

IRNDEATLFRMEDRDIQVN-FNDRTKIVI
 |.. .  ... . ..||| ||| |||..
YRTKYGIMYQLSNGTVQVNFFNDHTKIIL