Gene 91127.m00259 (T.vaginalis)

91127.m00259

Species: T.vaginalis
Alias: 91127.m00259, TvagK0798
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: LKB

Sequence

Name Sequence Type Origin Length Description Download
91127.m00259.AA Protein None 355 None Fasta, JSON
91127.m00259.kin_dom Protein Kinase Domain None 264 None Fasta, JSON

Protein domain

Protein domains of 91127.m00259.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 91127.m00259.AA S_TKc 35-298 27 3.1e-79 270.48 SMART 1-231 (231) Show / Hide 
Range on Protein: 35-298
Range on HMM: 1-231/231
Sequence Identity: 27% (76 aa)

YLCLCKLGSGASSKVYLAQDTVTNEYYALKMFKTSELSKTGNGLQTLEREIRNMRLVKHKNIIRMKEALHSKDEGIACIVFEWADC--GSIENLIERGFI
|  | |.|.|| .|||..... |....|.|. |           ....|||. ..  .|.||...... ..   .  ..|.| .|   |.   .|..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGR

------LDERVISRIFYQIVTGLQFLHDQGIVHQDIKPSNVLIFSDGSVKISDFGIGHRFQSADTVVGTPAYQAPEVFGSEEEPEEENLDEEPLDPCKED
      ..| .. ...|||. .|...|..||.| |.||.|.|. .   .||.|||.  ..   .|..||| | ||||.              . ..|| |
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---TTFCGTPWYMAPEVL--------------GYGKCKCD

VWSLGISLYQTKFLRLPYTGANVYEIASMIRTTDLEIPPDVSPELKDLITHMLTVDPMKRYSLHEVAA-------HPFI
.||.|. ||     . |.   .....  .|.          |||.||.| ..|..|| ||..  |. .       ||..
WWSCGCILYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 91127.m00259.AA CAMK 40-298 20 1.8e-74 239.22 In-house 1-425 (425) Show / Hide 
Range on Protein: 40-298
Range on HMM: 1-425/425
Sequence Identity: 20% (87 aa)

KLGSGASSKVYLAQDTVTN------------EYYALKMFKTSELSK------------------------TGNGLQTLEREIRNMRL-------VKHKNI
.||.|. .||.|.... |.            . .| |. ... |..                        ... .. ..|||. |..       ..|.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRMKEALHSKD-----------------EGIACIVF---EWADCG----S-IENLIERGF--------------ILDERVISRIFYQIVTGLQFLHDQGI
|.. |.  ...                 .   ..|.   | .. |       . ..|.|                ..||  .|.| ||. .....|...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHQDIKPSNVLIFSD-----------------GSVKISDFGIGHRFQS---------------------------ADTVVGTPAYQA-PEVFGS------
|| |.|| |.|. ..                 . .||.|||   .|..                             |..|||.| | |||. .      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

---EEEPEEENLDEEPLDPCKEDVWSLGISLYQTKFLRLPYTGA-------------NVYEIASMIRTTDLE-IPPD-----------------------
           ..|.| .. | |.||.|. ||     ..|. |              | ||.  .|.. . . .||                        
QNAT-------DEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHF

VSPELKDLITHMLTVDPMKRYSLHEVAAHPFI
||.| |||| .||.||| ||...... .||..
VSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Pkinase 91127.m00259.AA Pkinase 35-298 25 2.2e-70 244.96 Pfam 1-293 (293) Show / Hide 
Range on Protein: 35-298
Range on HMM: 1-293/293
Sequence Identity: 25% (78 aa)

YLCLCKLGSGASSKVYLAQDTVTNEYYALKMFKTSELSKTGNGLQTLEREIRNMRLVKHKNIIRMKEALHSKDEGIACIVFEWADCG----SIENLIE--
| .. |.|||....||....  |.. .|.| .| .. ..  .   .. .||. |. ..|.||.|.... ..  ..  ..|.|....|    .   .|.  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTW

RGFIL--DERVISRIFYQIVTGLQFLHDQGIVHQDIKPSNVLIFSDGSV----KISDFGIG----HRFQSADTVVGTPAYQAPEVFGSEEEPEEENLDEE
|.  .  .|... ...|||. ||...|..||.| |.||.|.|| ..| .    ||.|||.     .  .|..|..||| | ||||             . 
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIR-----------GG

PLDPCKEDVWSLGISLYQTKFLRLPYTGA------NVYEIASMIRTTDLEIPPDVS---------------------PELKDLITHMLTVDPMKRYSLHE
. .. | |.||.|. ||.  . |.|. |.      . ...  .|. ..|. . . .                     .|.||.|. .|..|| ||.. ..
QYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQ

VAAHPFI
.  ||..
ILQHPWF
Kinase 91127.m00259.AA Ciliate-E2 35-298 20 8.2e-57 193.54 In-house 1-365 (365) Show / Hide 
Range on Protein: 35-298
Range on HMM: 1-365/365
Sequence Identity: 20% (80 aa)

YLCLCKLGSGASSKVYLAQD-----------------------TVTNEYYALKMFKTSELSKTGNGLQTLE---------REIRNMRLVKHKNIIRMKEA
|  . |.|.|. ..||....                        |.. .||.|..| ...  . . .. .           | .......|.|||.|.|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

LHSKDEGIACIVFEWADCGSIENLIE-----RGFI------LDERVISRIFYQIVT---------------GLQFLHDQG-IVHQDIKPSNVLIFSDGSV
  .||.    .|.| .. |. . .|.     |...      ..|. |..|..||.                .|..|| .. |.| ||||.|.|.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KISDFGIGHRFQS-----------------------------------ADTVVGTPAYQAPEVFGSEEEPEEENLDEEPLDPCKEDVWSLGISLYQTKFL
||.|||.  ...                                    ..|..||| |.|||.......  .    ..     | |.||||. ||.  | 
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ---QKQKGYDYKCDIWSLGVILYEMLFG

RLPYTGANVYEIASMIRTTDLEIPPD------------------VSPELKDLITH----MLTVDPMKRYS-LHEVAAHPFI
..|.           |   ....|.                   .|.| ||||      || .|| ||..   ..  ||..
KPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 91127.m00259.AA STE 35-298 22 4.6e-54 185.93 In-house 1-359 (359) Show / Hide 
Range on Protein: 35-298
Range on HMM: 1-359/359
Sequence Identity: 22% (84 aa)

YLCLCKLGSGASSKVYLAQDT------VTNEY---------YALKMFKTSE-------------LSKTGNGLQTLEREIRNMRLVK--HKNIIRMKEALH
. .. |.|.||. .||.| .        |.|          .| |  . ..              .|  . .| ...||. |.  .  |.||..   .  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

SKD-----EGIACIVFEWADCGSIENLIE----RGFILD----------ERVISRIFYQIVTG-LQFLHDQGIVHQDIKPSNVLIFSDGSVKISDFGIGH
 ..     ..  .|. |. | ||.. .|.    .|. |.          | .|..| .||. | |..||...|.| ||||.|.|.     ||..|||.  
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

RFQS--------------------ADTVVGTPAYQAPEVFGSEEEPEEENLDEEPLDPC--KEDVWSLGISLYQTKFLRLPY-TGANV---YEIASMIRT
....                     .|.|||| . ||||   ....          ...  | |.||||. .      . |. .. .    ..|. ... 
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-R-------DKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHM

TD---------LEIP--PD--------------------VSPELKDLITHMLTVDPMKRYSLHEVAA--HPFI
 .          ..|  ||                    .|||.|| | . |. || || . ..     ||||
QQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 91127.m00259.AA ULK 35-298 26 4.4e-52 179.36 In-house 1-324 (324) Show / Hide 
Range on Protein: 35-298
Range on HMM: 1-324/324
Sequence Identity: 26% (89 aa)

YLCLCKLGSGASS-KVYLAQDTVT---NEYYALKMFKTSELSKTGNG------LQTLEREIRNMRLVK---HKN--IIRMKEALHSKDEGIACIVFEWAD
|    .||.|.   ||| . .  |   |.|.| ||   ....|  |       .| |..||..|.  |   |.|  |..... . ....   .|..|  .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

CGSIENLIE---------RGFILDERVISRIFYQIVTGLQFLHDQGIVHQDIKPSNVLIFSD------------GSVKISDFGIGHRFQS-------ADT
.|  |..|.         .. .| |  .  .|.||. |...||...|.| ||||.| ||  .            | .||.||| .  ...         |
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

VV------GTPAYQAPEVFGSEEEPEEENLDEEPLDPCKEDVWSLGISLYQTKFLRLP----YTGANVYEIASM----------IRTTDLEIP-----PD
 |      ||| | ||... ..       . ..| .  | |.||||. .|.  . . |    ..  . | |...          |... ...|     | 
CVNEKRIKGTPLYMAPQILQGQ-------GEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKDPK

VSPELKDLITHMLTVDPMKRYSLHEVAAHPFI
.|||.||||  ||..|. .| | .|. .||..
ISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 91127.m00259.AA ULK 35-298 26 2.4e-51 176.91 In-house 1-329 (329) Show / Hide 
Range on Protein: 35-298
Range on HMM: 1-329/329
Sequence Identity: 26% (89 aa)

YLCLCKLGSGASSKVYLAQDTVT----NEYYALKMFKTSELSKTGNG------LQTLEREIRNMRLVK----HKN----IIRMKEALHSKDEGIACIVFE
|    .||.|.  ||| . .  |    ||..| ||   .....  |       .| |..||..|.  |    |||    |..... . ....    |..|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

WADCGSIENLIE----------RGFILDERVISRIFYQIVTGLQFLHDQGIVHQDIKPSNVLIFSD------------GSVKISDFGIGHRFQS------
  . |  |..|.          .. .| |  .  .|.||. |...||...|.| ||||.|.||  .            | .||.||| .  ...      
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-ADTVV------GTPAYQAPEVFGSEEEPEEENLDEEPLDPCKEDVWSLGISLYQTKFLRLP----YTGANVYEIASM----------IRTTDLEIPPD-
 . | |      ||| | ||... ..       . ..| .  | |.||||. .|.  . . |    ..  . . | .           |... |..|.| 
MMMTCVNEKRLCGTPLYMAPQILQGQ-------GEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDG

----VSPELKDLITHMLTVDPMKRYSLHEVAAHPFI
    .|||.||||  ||..|. .| | .|. .||..
NDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 91127.m00259.AA CAMKL 35-204 27 5.2e-50 157.71 In-house 1-205 (297) Show / Hide 
Range on Protein: 35-204
Range on HMM: 1-205/297
Sequence Identity: 27% (57 aa)

YLCLCKLGSGASSKVYLAQD-TVTNEYYALKMFKTSELSKTGNGLQT-----------LEREIRNMRLVK---HKNIIRMKEALHSKDE----GIACIVF
|  .  || |. .|| ||..   |.| .| |. . . ...  . ..            ..|||. |....   |.|||.. | .  ..     .  ..| 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EWADCGS--IENLIERGFI----LDERVISRIFYQIVTGLQFLHDQGIVHQDIKPSNVLIFSDGS--VKISDFGIG---HR-----FQSADTVVGTPAYQ
| .. |.    . |..       ..|.   |.| ||| .....|..|||| |||| |.|. ..|.  .||.||| .    .      |  .|  |.|.|.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEVF
|||.|
APEIF
Kinase 91127.m00259.AA Ciliate-E2-Unclassified 35-298 23 5.6e-49 168.03 In-house 1-352 (352) Show / Hide 
Range on Protein: 35-298
Range on HMM: 1-352/352
Sequence Identity: 23% (85 aa)

YLCLCKLGSGASSKVYLAQDTVTNEYYALKMFKTSELSK-----TGNGLQTLEREIRNMR---------------LVKHKNIIRMKEALHSKDEGIACIV
|  . ..|.|. .|||..|.  ...|||.|. | .   |     . .    .| .. | .               |. |......|.  . .|.   .||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

FEWADCGSIENLIE-RGF----------------ILDERVIS-----RIFYQIVTGLQFLHDQG-IVHQDIKPSNVLIFSDG---SVKISDFGIGH----
 | .. |. .. |. |..                |..|. ..     ..|.||. ||..|| .. |.| ||||.|.|. ..|    .||.||||      
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

---------------RFQSADTVVGTPAYQ----APEVFGSEEEPEEENLDEEPLDPCKEDVWSLGISLYQTKFLRLPYTGANVYE--------------
               ..| ..|..||| |.    ||||.....  ..           | |.||||. ||.  | ..|. . | ..              
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA--------YKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYR

--IASMIRTTDLEIPP--------DVSPELKDLIT----HMLTVDPMKRYSLHEVAAHPFI
  . . |   ....|.        ..||| ||.|.     || ..| ||... ..  ||..
KQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 91127.m00259.AA CAMKK 140-298 26 9.9e-46 142.86 In-house 180-396 (396) Show / Hide 
Range on Protein: 140-298
Range on HMM: 180-396/396
Sequence Identity: 26% (58 aa)

RIFYQIVTGLQFLH-DQG-------------------IVHQDIKPSNVLIFSDG---SVKISDFGIGHRF-QSADT--------------VVGTPAYQAP
..| ... ||..|| .|.                   |.| ||||.| || ..|    |||.|||. | | .. .|               .||||..||
KYFRDCIKGLEYLHNYQKACSYIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTPAFMAP

EVFGSEEEPE-----EENLDEEPLDPCKEDVWSLGISLYQTKFLRLPYTGANVYEIAS---MIRTTDLEIPP-------------DVSPELKDLITHMLT
|..  |.. |       .. .   .  . |.|.||..||   |...|. . |  ..     .|   ... |.             ..|..|||||. || 
ELCSKENQKENYNGYK-YRFRFIYCGKAADIWALGVTLYCFVFGKCPFWHNNLMQLHHNYMKIKNDPIKFPENKEMLNNVSIYCPEISEDLKDLIKRMLE

VDPMKRYSLHEVAAHPFI
 .|.|| .....  ||..
KNPTKRITIPQIKVHPWV
Kinase 91127.m00259.AA NEK 35-204 27 8.9e-35 120.08 In-house 1-196 (286) Show / Hide 
Range on Protein: 35-204
Range on HMM: 1-196/286
Sequence Identity: 27% (54 aa)

YLCLCKLGSGASSKVYLAQDTVTNEY-----YALKMFKTSELSKTGNGLQTLE-REIRNMRLVKHKNIIRMKEALHSKDEGIACIVFEWAD-CGSIENL-
|  . |.|.|. .|||..... ..       |..|  .....|      | .   |.|  .  || ||.. ...   .. .  ||| |...  |  ... 
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSE--KEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKI

--IERG----FILDERVISRIFYQIVTGLQFLHDQ-----GIVHQDIKPSNVLIFSDGS----VKISDFGIGHRFQS-----ADT-VVGTPAYQAPEVF
  |...      ..|..| ..|.|.. .|...||.      |.| ||||.|. . ....    ||| ||||  . ..     | | .|||| | .|||.
KSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGIS-KVLNHTTDMAYTTQVGTPYYMSPEVC
Kinase 91127.m00259.AA MARK 140-204 45 1.4e-20 64.12 In-house 108-177 (262) Show / Hide 
Range on Protein: 140-204
Range on HMM: 108-177/262
Sequence Identity: 45% (32 aa)

RIFYQIVTGLQFLHDQGIVHQDIKPSNVLIFSDG--SVKISDFGIGHRFQSAD---TVVGTPAYQAPEVF
||| ||| .....|...||| |||| |.|| ..|   .||.||| . ....     |  |||.| |||.|
RIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIF
Kinase 91127.m00259.AA CAMKL 226-298 29 7.1e-17 50.24 In-house 218-297 (297) Show / Hide 
Range on Protein: 226-298
Range on HMM: 218-297/297
Sequence Identity: 29% (24 aa)

DVWSLGISLYQTKFLRLPYTGANV--------YEIASMIRTTDLE-IPPDVSPELKDLITHMLTVDPMKRYSLHEVAAHPFI
|.||.|. ||   . .||  ....        |.    ...   . |...|| ...||| .||.|.|.||...|..  ||. 
DIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 91127.m00259.AA MARK 226-298 34 1.8e-16 50.55 In-house 188-262 (262) Show / Hide 
Range on Protein: 226-298
Range on HMM: 188-262/262
Sequence Identity: 34% (27 aa)

DVWSLGISLYQTKFL---RLPYTGAN--VYEIASMIRTTDLEIPPDVSPELKDLITHMLTVDPMKRYSLHEVAAHPFI
|.||||. ||   |.   ..|. |..    |.   |.. . .||. ||.|...||  .|||.|..| ...|.  ||..
DIWSLGVVLY---FMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 91127.m00259.AA NEK 226-298 32 1.4e-14 48.1 In-house 206-286 (286) Show / Hide 
Range on Protein: 226-298
Range on HMM: 206-286/286
Sequence Identity: 32% (26 aa)

DVWSLGISLYQTKFL--RLPYTGA--NVYEIASMIRTT-DLE-IPPD--VSPELKDLITHMLTVDPMKRYSLHEVAAHPFI
|.||||  ||.   |  . |  .   | .. .  |.   . . ||.    |..|..||. ||..|| .|.|  .. ..|||
DIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase 91127.m00259.AA MARK 35-99 30 3.5e-12 36.29 In-house 1-64 (262) Show / Hide 
Range on Protein: 35-99
Range on HMM: 1-64/262
Sequence Identity: 30% (20 aa)

YLCLCKLGSGASSKVYLAQDTVTNEYYALKMFKTSELSKTGNGLQTLEREIRNMRLVKHKNIIRM
|  |  .| |. .||.||... |.. .|.|. .   |..  . .. ..|||. |....|.|||..
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQW-MKNVMREIEIMKKLDHPNIIKL
Kinase 91127.m00259.AA TyrKc 35-298 20 3.7e-11 -42.34 SMART 1-280 (280) Show / Hide 
Range on Protein: 35-298
Range on HMM: 1-280/280
Sequence Identity: 20% (63 aa)

YLCLCKLGSGASSKVYLAQDTVTNEYYALKMFKTSELSKTGNGLQTLEREIRNMRLV--KHKNIIRMKEALHSKDE-----GIACIVFEWADCGSIENLI
   . |||.||  .||... .   .  | || | .        .. . ||.| |. .  .|.||.|.  .  .. .     .  .||.| .. |.  . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

--ERGFILDERVISRIFYQIVTGLQFLHDQGIVHQDIKPSNVLIFSDGSVKISDFGIGHRFQSA-------DTVV-----GTP-----AYQAPEVFGSEE
   |.  |  .    . .||  | ..||.....| |.   |.|. ... |||||||      .        |. .     |.         |||..    
RKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI----

EPEEENLDEEPLDPCKE------DVWSLGISLY-QTKFLRLPYTG-----ANVYEIASMIRTT-DLEIPPD--------VSPELKDLITHMLTVDPMKRY
               .       |||| |. ..    .   || |      . .|.   ...   ...||.         ..|. ....     || .| 
--------------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRP

SLHEVAAHPFI
.  |.  | ..
TFSEI--HECF
Kinase 91127.m00259.AA Pkinase_Tyr 81-181 25 8.1e-08 27.11 Pfam 50-156 (270) Show / Hide 
Range on Protein: 81-181
Range on HMM: 50-156/270
Sequence Identity: 25% (27 aa)

LEREIRNMRLV-KHKNIIRMKEALHSKDEG-IACIVFEWADCGSIENLIER----GFILDERVISRIFYQIVTGLQFLHDQGIVHQDIKPSNVLIFSDGS
. ||.. |.   .|.||.|.  .  ...|    .||.| . .|.  .   .    .  |.   .  . .||  |...|......| |.   |.|. ... 
FMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNV

VKISDFG
|||.|||
VKICDFG
Kinase 91127.m00259.AA CAMKK 35-98 21 9.1e-05 10.57 In-house 1-91 (396) Show / Hide 
Range on Protein: 35-98
Range on HMM: 1-91/396
Sequence Identity: 21% (20 aa)

YLCLCKLGSGASSKVYLAQDTVT-NEYYALKMFKT----SELSK----------------------TGNGLQTLEREIRNMRLVKHKNIIR
|  . ..|.|.  || || .. . . .|| | |.       | |                        |.......||  |... |.||..
YELMKEIGQGQFGKVKLAYNEYDTQKHYAIKIFNKKYVFKKLKKKQQFYRDPPKRMTNMNQNGEMQMMNPFDCVYQEIAIMKKCNHPNIVK