Gene 91127.m00206 (T.vaginalis)

91127.m00206

Species: T.vaginalis
Alias: TvagK0412, 91127.m00206
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
91127.m00206.AA Protein None 394 None Fasta, JSON
91127.m00206.kin_dom Protein Kinase Domain None 246 None Fasta, JSON

Protein domain

Protein domains of 91127.m00206.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH 91127.m00206.AA PH 3-88 18 0.000685 16.68 Pfam 4-76 (92) Show / Hide 
Range on Protein: 3-88
Range on HMM: 4-76/92
Sequence Identity: 18% (16 aa)

EGWLSKKGSVKGMWMRRKVYFDDKSFILSKDENNQNNELEIPMKNAVSISELDNGSLNVVFMNNQPLIFCSKNETIIKEFQFSFKT
||||.|||  .. | .| . . ..  .. ||..  .    ||.... .. .....        ..| .|. .. .  ... |....
EGWLHKKG-KRKSWKKRWFVLFNNCLYYYKDDK-YRPKGSIPLSDC-QVTKVPDN--------KRPHCFQIRT-DR-RTYYFQAES
Kinase 91127.m00206.AA AGC 104-347 20 3e-88 227.54 In-house 1-395 (395) Show / Hide 
Range on Protein: 104-347
Range on HMM: 1-395/395
Sequence Identity: 20% (83 aa)

FICK--IGSGYSSEVYLAQNT------QTNELVVLKTANKNN-SS-----SMKALYVE------------NKILNEFK----------HPMIIS-KKGVV
|  .  || |  ..|||..        .|...  .|  .|           ..  ..|             .|| . .          || |..  .   
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ENSKR--YSLCLEYIS--------GGD-LYFWMNRV--INR--SNEDILIIMSE-------LVIALEFLHS-NGIIYRD-LKPENILINSSGHIKLSDFG
.. ..    ...||..        ||.  .|....    ..  . | . ....|       .| |||.||| .|||.|| |||||||... |||||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSTI------------------------------------------------------SETSTEICG--TSSYMAPEMIKHQLYSNKVDIWA--FGILLF
|...                                                       .. . .||  |  |||||..    |.  .|.|.  .|.|..
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EINFGYNPFSRD----------IKEKTMKAIV------EEELKIP----------QNFNKDLSELLRNVLKKDPKERFS----------VQQIKESAYF
|  .|| ||. |           ...... |       ....|.|          ..| ...  |..  |.|||..|            ...||.  .|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
S_TKc 91127.m00206.AA S_TKc 102-347 29 7.8e-77 262.48 SMART 1-231 (231) Show / Hide 
Range on Protein: 102-347
Range on HMM: 1-231/231
Sequence Identity: 29% (77 aa)

YLFICKIGSGYSSEVYLAQNTQTNELVVLKTANKNNSSSMKALYVENKILNEFKHPMIISKKGVVENSKRYSLCLEYISG--GDLYFWMNRVIN------
| .. |||.|  ..||..... |...| .|  .       . .. | .|| . .|| |.  ..| .. ... ...||..|  |||.  . .         
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

RSNEDILIIMSELVIALEFLHSNGIIYRDLKPENILINSSGHIKLSDFGLSTISETSTEICGTSSYMAPEMIKHQLYSN-KVDIWAFGILLFEINFGYNP
 .  ..  .| ... |||..||.|||.|||||||||...  |||..||||...    | .|||  |||||..    |.  |.|.|..|..|.|   || |
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPP

FSRDIKEKTMKAIVEEELKIPQNFNKDLSELLRNVLKKDPKERFSVQQIKE-------SAYF
|.    ....| |.           ... ...|. |.|||..| .. .. .         .|
FP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase 91127.m00206.AA Pkinase 102-347 28 1.2e-68 239.13 Pfam 1-293 (293) Show / Hide 
Range on Protein: 102-347
Range on HMM: 1-293/293
Sequence Identity: 28% (86 aa)

YLFICKIGSGYSSEVYLAQNTQTNELVVLKTANKNNSSSMKALYV----ENKILNEFKHPMIISKKGVVENSKRYSLCLEYISGG----DLYFWMN----
| .. ||||| ...||....  |...|..|. .| . .| |  .     | .|.....|| |.  ....|..... ...||  ||    ||. ..     
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

-RVINRSNEDILIIMSELVIALEFLHSNGIIYRDLKPENILINSSGHI----KLSDFGL-----STISETSTEICGTSSYMAPEMIK-HQLYSNKVDIWA
 ...  | ...  .| ... .||..||.|||.||||||||||.. |||    |..||||        ..  | .|||. ||||| |. .| |. |||.|.
GCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

FGILLFEINFGYNPFSRD---IKEKTMKAIVEEELKIPQNFN-------------------------KDLSELLRNVLKKDPKERFSVQQIKESAYF
.|..|.|  .|. ||. .   ..  ........ .. |  |.                         ... ..... |.||||.| . .||... .|
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 91127.m00206.AA CAMK 107-347 16 2.7e-65 209.08 In-house 1-425 (425) Show / Hide 
Range on Protein: 107-347
Range on HMM: 1-425/425
Sequence Identity: 16% (70 aa)

KIGSGYSSEVYLAQNTQTN------------ELVVLKTANKN----------------------------NSSSMKALYVENKILNE-------FKHPMI
..|.|  ..|.|.....|.            . |  |  .|.                            . ...| .. | .|..         .|| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

ISKKGVVE------------NSKR--------YSLCL---EYISGGDLYFW-MNRVINRSN------------------EDILIIMSELVIALEFLHSNG
|.   | |            . ..        . . .   ||.|||.|..   .... ...                  ..   ..  .. |....||..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IIYRDLKPENILINSS-----------------GHIKLSDFGLSTI---------------------------SETSTEICGTSSYMA-PEMIKHQL---
|. |||||||||....                 . ||..|||....                            .  .. ||| .||| ||... .    
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

-----------YSNKVDIWAFGILLFEINFGYNPFSRD-------------IKEKTMKAIVEEELK-IPQNFNK-----------------------DLS
           |. |.|.|. |..|.    || ||  |               ..... | . .   .|  | .                       .  
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

ELLRNVLKKDPKERFSVQQIKESAYF
 |.|. |..||..|....|...   .
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 91127.m00206.AA Ciliate-E2 102-347 22 1.9e-60 206.23 In-house 1-365 (365) Show / Hide 
Range on Protein: 102-347
Range on HMM: 1-365/365
Sequence Identity: 22% (84 aa)

YLFICKIGSGYSSEVYLAQNTQTNE--------------------------LVVLKTANKNNSSSMKALY----------VENKILNEFKHPMIISKKGV
| || |||.|  . ||.... ....                          . ..|  .... .... ..           | .|| . .|| ||  . .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VE--NSKRYSLCLEYISGGDLYFWMNRV-INRSNE----------DILIIMSELV---------------IALEFLHSNG-IIYRDLKPENILINSSGHI
 .  . . . | .||..||||. ...   ..| .|           |. || ...                |||.|||.. ||.||.||||||.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLSDFGLSTISETSTE-----------------------------------ICGTSSYMAPEMIK---------HQLYSNKVDIWAFGILLFEINFGYNP
|..|||||..  .. .                                   ||||  |||||...         .. |. |.|||..|..|.|  ||. |
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FSRDIKEKTMKAIVEEELKIP------------------QNFNKDLSELLRN----VLKKDPKERFS-VQQIKESAYF
|        .. | . ....|                  ..  ..   |...     |.|||..|..  .||..  .|
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 91127.m00206.AA AktR 102-347 29 2.2e-58 200.27 In-house 1-268 (268) Show / Hide 
Range on Protein: 102-347
Range on HMM: 1-268/268
Sequence Identity: 29% (80 aa)

YLFICKIGSGYSSEVYLAQNT-QTNELVVLKTANK---NNSSSMKALYVENKILN-EFKHPMIISKKGVVENSKRYSLCLEYISGGDLYFWMNRVINRSN
. ..  .|.|  ..|||.|   ...... .|   |    .   |.... | .|.  . .|| |.  .   .. .   ...||. ||.|..  ..    |.
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

EDILIIMSELVIALEFLHSN-GIIYRDLKPENILINSSGHIKLSDFGLST------ISETSTEICGTSSYMAPEMIKH-QLYSNKVDIWAFGILLFEINF
|........ ..|||.||..  ||||||||||||. . ||.|..|||||        .|. . .|||  |||||||.  . .   ||.|||||...|. .
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GYNPFSRDIKEKTMKAIVEEE-LKIPQN--FNKDLSELLR-NVLKKDPKERFS-----VQQIKESAYF
|. ||  . ..   . | ... .|.|..  | . . .|.    |.|.|..|        ..||.   |
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 91127.m00206.AA Ciliate-E2-Unclassified 102-347 22 2.4e-58 200.17 In-house 1-352 (352) Show / Hide 
Range on Protein: 102-347
Range on HMM: 1-352/352
Sequence Identity: 22% (79 aa)

YLFICKIGSGYSSEVYLAQNTQTNELVVLKTANKNNSSS----------------MKALY------VENKILNE----FKHPMIISKKGVVENSKRYSLC
| .| .||.|  ..||..|. ..... ..|...|... .                |. .         |||...    ..|| |. .  . .. .   . 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKY-NKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

LEYISGGDLYFWMNRVIN-----------------RSNEDIL-----IIMSELVIALEFLHSNG-IIYRDLKPENILINSSG---HIKLSDFGLST----
.||. |||| ....   .                  . . ..      .. ... .||.||... ||.||.||||||....|   .||..|||.|     
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

---------------ISETSTEICGTSSYM----APEMIKHQLYSNK----VDIWAFGILLFEINFGYNPFS-RDIKE---------------KTMKAIV
               ... .. .||| .||    |||... | |...    .|||..|..|.|. ||| ||. .. ..                  . | 
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

EEELKIPQNFN----KDLS--------ELLRNVLKKDPKERFSVQQIKESAYF
. ....|   .    |..|        .||.  |||.|..| . .||..  .|
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 91127.m00206.AA CAMKL 102-347 26 9.8e-57 179.51 In-house 1-297 (297) Show / Hide 
Range on Protein: 102-347
Range on HMM: 1-297/297
Sequence Identity: 26% (78 aa)

YLFICKIGSGYSSEVYLAQNTQT-NELVVLKTANKN----NSSSMKA-----------LYVENKILNEFK---HPMIISKKGVVENSKR------YSLCL
| ..  .| |  ..| ||....| .| |  |  .|.    .  ..|            .. | .|.  ..   || ||.   |.|...       . | .
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYISGGD--LYFWMNRVIN----RSNEDILIIMSELVIALEFLHSNGIIYRDLKPENILINSSG--HIKLSDFGLSTI--------SETSTEICGTSSYM
||.|||.  |. .  .  .     . ..   .   .| |....||.||. ||.||||||. ..|   ||..|||.|..         .. .. ||. .||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEMIKH--QLYS-NKVDIWAFGILLFEINFGYNPFSRD--------IKEKTMKAIVEEELKIPQNFNK-DLSELLRNVLKKDPKERFSVQQIKESAYF
|||...   . |   |||||. |..|. . .|| ||  |         . . .. | .   ..|  .   |.  |.|  |...|..|....||..   .
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 91127.m00206.AA RSK 174-347 33 3.8e-55 189.52 In-house 78-278 (278) Show / Hide 
Range on Protein: 174-347
Range on HMM: 78-278/278
Sequence Identity: 33% (67 aa)

LCLEYISGGDLYFWMNRVINR---SNEDILIIMSELVIALEFLHSNGIIYRDLKPENILINS---SGHIKLSDFGLSTISETS-TE----ICGTSSYMAP
|..||..||.|.    .       | ..  ..|.|.| |.|.||. |||.||||||||| ..   .|||||.|||.. ..  . ..     |.|  ||||
LIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAP

EMIK---HQL-YSNKVDIWAFGILLFEINFGYNPFSR---DIKEKTMKAIVEEE--LKIP--QNFNKDLSELLRNVLKKDPKERFS-----VQQIKESAY
||.|   .|  ..  .|.| .|.|..|  .|. ||     . ....|| | . .  |..|  |.  ..  .|.|  |..||. | .     ...||....
EMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPW

F
|
F
Kinase 91127.m00206.AA TKL 108-345 18 6.6e-50 172.12 In-house 1-364 (364) Show / Hide 
Range on Protein: 108-345
Range on HMM: 1-364/364
Sequence Identity: 18% (68 aa)

IGSGYSSEVYLAQNTQTN--------ELVVLKTANKNN---------------------------SSSMKALYVENKILNEFKHPMIISKKGVVENSKR-
|||| ..||| ..  ...        . |. |. ...|                           |  .. . .| .... ..|| |.. .|.. ...  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YSLCLEYISGGDLYFWMNRVINRSNEDILIIMSELVIALEFLHSNG--------IIYRDLKPENILINSSGH--------------IK
            . .  ||..||.|.  ..       . .. .. .   ....|||..        ||.||||..|||... ..              .|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

LSDFGLSTISETSTE-----------------------ICGTSSYMAPEMIKHQ----------------LYSNKVDIWAFGILLFEINFGYNPFSRDIK
..|||||.  ..|..                       .|||  .||||... |                 || |.|...|||.|.||  .  |.. .  
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY

EKTM---------KAIV--EEELKIP------------QNFNKDLSELLRNVLKKDPKERFSVQQIKESA
.  .         . ..   . . ||             .. .....|.    . ||..| | |.|..  
MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 91127.m00206.AA STE 102-347 20 4.4e-49 169.39 In-house 1-359 (359) Show / Hide 
Range on Protein: 102-347
Range on HMM: 1-359/359
Sequence Identity: 20% (73 aa)

YLFICKIGSGYSSEVYLAQNT------QTNEL---------VVLKTANKNNS-----------------SSMKALYVENKILNEFK--HPMIISKKGVVE
. .| |||.| . .||.| |       .|.|.         .  |  |..|.                 . |. .  | ||.....  || |.   |  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

NS-------KRYSLCLEYISGGDLYFWMNRVINRSN-------------EDIL-IIMSELVIA-LEFLHSNGIIYRDLKPENILINSSGHIKLSDFGLST
.            .|.||..|| |   ....  . .             |... .|  ... . |..|||..|| ||.|| |||.     .||.|||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

-ISE-------------------TSTEICGTSSYMAPEMIKH------QLYSNKVDIWAFGILLFEINFGYNPFSRDIKEKTMKAIV-------------
 ...                    .. ..||  .||||.|.       . |. |.||| .|... |   |  |..     . | .|              
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---EEELKIPQ-------------------NFNKDLSELLRNVLKKDPKERFSVQQIKE--SAYF
   ..  ..|.                   .. ... . ... |.|||..| ...|  .     .
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 91127.m00206.AA MARK 206-347 35 4.4e-43 138.78 In-house 113-262 (262) Show / Hide 
Range on Protein: 206-347
Range on HMM: 113-262/262
Sequence Identity: 35% (53 aa)

LVIALEFLHSNGIIYRDLKPENILINSSG--HIKLSDFGLSTIS---ETSTEICGTSSYMAPEMIKHQLYS-NKVDIWAFGILLFEINFGYNPFSRDI--
.| |....||..|. ||.||||||| . |   ||..|||.|..    .  .. ||| .|||||... . |   |||||. |..|. .  || ||  |   
IVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQD

KEKTMKAIVEEELKIPQNFNKDLSELLRNVLKKDPKERFSVQQIKESAYF
 .. .| |. .. .|| .  |..  |.. .|. .|.|| ....| .   .
YKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 91127.m00206.AA TyrKc 102-345 22 2.1e-19 71.68 SMART 1-280 (280) Show / Hide 
Range on Protein: 102-345
Range on HMM: 1-280/280
Sequence Identity: 22% (64 aa)

YLFICKIGSGYSSEVYLAQNTQTNELVVLKTANKNNSSSMKALYVENKILNEF--KHPMIISKKGVVENS-------KRYSLCLEYISGGDL--YFWMNR
  .. |.|.|   |||... .   . |  |. ...    ..... | .|. ..  .|| |.   ||.  .       . . . .|| ..|||  |   .|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

VINRSNEDILIIMSELVIALEFLHSNGIIYRDLKPENILINSSGHIKLSDFGLSTISETS-------TEIC-----GTSS-----YMAPEMIKHQLYSNK
    ...| | ..       |.|||...| |||   |.|... ...| ||||||   .           .      |. .      |||| |..  .. |
PK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTK

VDIWAFGILLFEI-NFGYNPFSRD----IKEKTMKAIVEEE--LKIPQN--------FNKDLSELLRNVLKKDPKERFSVQQIKESA
 |.|.||....||  .|  | . .    .. . . . |..   ...|.|          ... .. .   . ||..| . ..|.|  
SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 91127.m00206.AA MARK 102-185 33 7.2e-13 38.57 In-house 1-90 (262) Show / Hide 
Range on Protein: 102-185
Range on HMM: 1-90/262
Sequence Identity: 33% (30 aa)

YLFICKIGSGYSSEVYLAQNTQTNELVVLKTANK--NNS-SSMKALYVENKILNEFKHPMIISKKGVVE--NSKR-YSLCLEYISGGDLY
| ..  || |  ..|.||... |.. | .|. .|   |   .|| .. | .|.   .|| ||.   |.|  ....   | .||.|||.||
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELY
Kinase 91127.m00206.AA Pkinase_Tyr 227-286 29 3.6e-11 38.45 Pfam 141-207 (270) Show / Hide 
Range on Protein: 227-286
Range on HMM: 141-207/270
Sequence Identity: 29% (20 aa)

NILINSSGHIKLSDFGLSTIS-ETSTEICGTSS-------YMAPEMIKHQLYSNKVDIWAFGILLFEI
|.|.......| .||||.    ....    ...        |||| |..  .. | |.|.||.|..||
NCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEI
Kinase 91127.m00206.AA Pkinase_Tyr 102-185 24 7.6e-05 17.04 Pfam 1-95 (270) Show / Hide 
Range on Protein: 102-185
Range on HMM: 1-95/270
Sequence Identity: 24% (23 aa)

YLFICKIGSGYSSEVYLAQNT----QTNELVVLKTANKNNSSS---MKALYVENKILNEF-KHPMIISKKGVVE-NSKR--YSLCLEYISGGDLY
  |. |.|.|   |||..  .    .|.  |  |. . . ...   ....  | ||. .. .|| |..  ||.   ..   . . .||  .|||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL