Gene 95695.m00061 (T.vaginalis)

95695.m00061

Species: T.vaginalis
Alias: 95695.m00061, TvagK0766
External Links:
Annotation:

Classification

Group: CMGC
Family: GSK

Sequence

Name Sequence Type Origin Length Description Download
95695.m00061.AA Protein None 347 None Fasta, JSON
95695.m00061.kin_dom Protein Kinase Domain None 285 None Fasta, JSON

Protein domain

Protein domains of 95695.m00061.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 95695.m00061.AA GSK 37-321 35 6.8e-127 389.8 In-house 1-328 (328) Show / Hide 
Range on Protein: 37-321
Range on HMM: 1-328/328
Sequence Identity: 35% (119 aa)

YLGYRLIGSGTFGSVYKARTI-----AGKV----VAIKSVKQDPQYK-NRELEILKIL---HSRYCIKLKDHYFTRKNNGKD--VYLN-IVMDYFPYTVH
|  ...||.|.|| ||.|  .      ...    |||| | ||. || ||||.|.|.|   .   ...|| .. .  ..  .  ||.| .||.| |.|..
YEEMKVIGHGSFGVVYQAYMNSPSNETKEIWLGPVAIKKVWQDKRYKCNRELQIMKMLGKLDHPNIVRLKYFFYMHYEKKDENHVYCNCLVMEYMPQTLY

SYTMKLRDQQKRIGNTLLKILAYQIFAGLRYLHAKGIVHRDIKPENIMFSPVTGKLKITDFGSAKVIKP--GDTSVSYIASRFYRAPELILGCEQYTGAI
..  . ....... . ..|...||.| ||.||| .||.||||||.||   | ||.||| |||||| ..|  . ...||| ||.|||||||.||..|| .|
QVIRHYVKNKQQMPIIHIKLYMYQMFRGLAYLHSHGICHRDIKPQNILVDPDTGVLKICDFGSAKQLEPNKNEPNISYICSRYYRAPELIFGCTNYTCQI

DVWAAGCVIAEMLRMGEVLFEGMTGTGQIIPIIQLLGKPTQSDLSSFQHTA-----P-------VPTSLTK-------------------PIIKLEDQLP
||| .|||.||||  |..|| | ..  |.. ||..|| ||. ...|.         |        |....|                    . ..... .
DVWSCGCVMAEML-KGQPLFPGDSSVDQLVEIIKMLGTPTKEQIQSMNPSYPEFKFPYWSFQQIKPHPWQKNDTKYEYQTYYHKKYRTVYMFKWCHTDMQ

KTTNSKLIALLKQIFVYNPTKRITAAQCLQHPYF
      .| |.....||.|.||... ....||.|
-----DWIDLISKCLVYDPKKRLSPLEACAHPFF
Kinase 95695.m00061.AA CMGC 37-321 21 1.8e-99 327.58 In-house 1-513 (513) Show / Hide 
Range on Protein: 37-321
Range on HMM: 1-513/513
Sequence Identity: 21% (109 aa)

YLGYRLIGSGTFGSVYKART---------------IAGKVVAIKSVKQDPQYKN----------------RELEILKIL-----------------HSRY
|   . ||.||.| |||.|                  ...|||| .|... |..                ||..||| |                 |  .
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

CIKLKDHYFTRKNNGK-----------DVYLNIVMDYFPYTVHSYTMKLR------------------------DQQKRIGNTLLKILAYQIFAGLR--Y
..||.|.. .....|.           ...|..|..| ... . |  . .                         . | . . . .  .|||. ||   |
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKY

LHAKG--IVHRDIKPENIMFSP-------------------VTGKLKITDFGSAKVIKPGD----------------------TSVSYIASRFYRAPELI
.| ..  |.|||.|||||....                   . |.||| |||.|. . | .                      .  .|...|.|||||..
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEIL

LGCEQYT---------GAIDVWAAGCVIAEMLRM-------GEVLFEGMTG-----------TGQIIPIIQLLGKPT---------------QSDLSSFQ
||...||          .||.|..||..|||..        |. || | ..             |.  |...||.||               . .  .. 
LGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMI

H--------------------TAP----------VPTSLTKPIIKLEDQLPK-------------------------------TTNSKLIALLKQIFVYN
                     .             |.   ||. .|.  .|.                                 ....| |||....|.
KLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYD

PTKRITAAQCLQHPYF
|.|||||.|.||||||
PDKRITAEQALQHPYF
Kinase 95695.m00061.AA S_TKc 37-321 27 1.2e-78 268.51 SMART 1-231 (231) Show / Hide 
Range on Protein: 37-321
Range on HMM: 1-231/231
Sequence Identity: 27% (81 aa)

YLGYRLIGSGTFGSVYKARTIA-GKVVAIKSVKQDPQYKNRELEILKILHSRYCIKLKDHYFTRKNNGKDVYLNIVMDYFPY---TVHSYTMKLRDQQKR
|   |.||.|.||.|||.| .  |..|||| .|   .   ||..|||  |  . .||.|.. .        .| .||.| .    ....|  | . . .|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---EHIRREIQILKK-HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--IGNTLLKILAYQIFAGLRYLHAKGIVHRDIKPENIMFSPVTGKLKITDFGSAKVIKPGDTSVSYIASRFYRAPELILGCEQYTG-AIDVWAAGCVIAE
  .     . ..|||. .| |.| .||.|||.|||||...     .||.|||.|...       ... ...|.|||..    .|.. ..|.|. ||...|
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE

MLRMGEVLFEGMTGTGQIIPIIQLLGKPTQSDLSSFQHTAPVPTSLTKPIIKLEDQLPKTTNSKLIALLKQIFVYNPTKRITAAQCLQ-------HPYF
||  |. .|.      |.  .....|                                    . .. .........|.||.|| ..||       ||.|
MLC-GYPPFP------QMQMMFKKIG-----------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 95695.m00061.AA CDK 37-321 30 8.2e-72 228.99 In-house 1-284 (284) Show / Hide 
Range on Protein: 37-321
Range on HMM: 1-284/284
Sequence Identity: 30% (98 aa)

YLGYRLIGSGTFGSVYKARTIA-G-----KVVAIKSVK---Q----D----PQYKNRELEILKILHSRYCIKLKDHYFTR---KNNGKDV---YLNIVMD
|     || ||.| |||||    |     ..||.| ..   .    .    |.   ||  .|| |   . .||.| . |    .|| ||     | .|..
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNN-KDKHENKLYMVFE

YFPYTVHSYTMKLRDQQKRIGNTLLKILAYQIFAGLRYLHAKGIVHRDIKPENIMFSPVTGK-----LKITDFGSAKVIK-------PGDTSVSYIASRF
| ..   .| |.             | . .|.  || |.| ..|.|||.|| ||. .  .|.     |||.||| |.          |  |  . .  . 
YMDHDLKKY-MD------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINN-NGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLW

YRAPELILGCEQYT--GAIDVWAAGCVIAEMLR--MGEVLFEGMTGTGQIIPIIQLLGKPTQSDLSSFQHTAPVPTSLTKPIIKLEDQLPKTTNSKLIAL
|||||| ||...|.   .||.|..||..|||..  ... || | . . |.  |....| || ..  .. .                             |
YRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY------------------------DL

LKQIFVYNPTKRITAAQCLQHPYF
| . ..|.|.|||.| |.||||||
LNKMLCYDPKKRISAEQALQHPYF
Kinase 95695.m00061.AA Pkinase 37-321 27 2.1e-68 238.33 Pfam 1-293 (293) Show / Hide 
Range on Protein: 37-321
Range on HMM: 1-293/293
Sequence Identity: 27% (87 aa)

YLGYRLIGSGTFGSVYKARTIAG-KVVAIKSVKQDPQYKNR--------ELEILKILHSRYCIKLKDHYFTRKNNGKDVYLNIVMDYFPYTVHSYTMKLR
|   | ||||.||.|||.. .   |.||.| .| . . ..         |..|.| |.. . ..|.| . .      . .. .||.| . ...   | | 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED------KDHIYMVMEYCEGGLY--VMDLF

-----DQQKRI--GNTLLKILAYQIFAGLRYLHAKGIVHRDIKPENIMFSPVTGKL----KITDFGSAKV--IKPGDTSVSYIASRFYRAPELILGCEQY
     ......      .|  .|||. || |.|..||.|||.|||||...  .| .    ||.|||.||.  . ..    ..  ...|.|||.|.|.. |
DYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYY

TGAIDVWAAGCVIAEMLRMGEVLFEGM----TGTGQIIPIIQLLGKPTQSDLSSFQHTAPVPTSLTKPIIKLEDQLPKTTNSKLIALLKQIFVYNPTKRI
. ..|.|..||...|||  |. .| |     .   |.  | . .|.|. .| .      . .   . .  . .  . . ... .. ..| .. ..|.||.
GPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-HF-HWTF-HNWSEECKDFIKWCLCKDPKKRP

TAAQCLQHPYF
||.|.||||.|
TAEQILQHPWF
Kinase 95695.m00061.AA CDK-Unclassified 37-321 27 1.8e-55 180.88 In-house 1-324 (324) Show / Hide 
Range on Protein: 37-321
Range on HMM: 1-324/324
Sequence Identity: 27% (92 aa)

YLGYRLIGSGTFGSVYKAR-TIAGKVVAIK--SVKQ--D------------PQYKNRELEILKILHSRYCIKLKDHYFTRKNNGKDVYLN-------IVM
|   . .|.||||.|.||. .   | ||||  .|..  .            ..  .||. .|. ..... ||. | .  .    |  |         .||
YRMQCKYGEGTFGCVCKAIDFQTQKHVAIKKIMVNNKKGNKCKHILPLLNSKITDQREISCLQNCNHMNIIKFMDMHYDHDRCSKNPYYDNLHPSFYMVM

DYFPYTV----HSYTMKLRDQQKRIGNTLLKILAYQIFAGLRYLHAKGIVHRDIKPENIMFSPVT----GKLKITDFGSAKVIK-------------PGD
.| |||     |.    |  .|        .  . |.. |. ||| ..| ||||||.||| .  .     .||| |||.|                 |..
EYMPYTWYNQLHNNRYNLSMCQ-------IRNFMHQMLEGIAYLHCNKIMHRDIKPQNIMITNNNSTVSPMLKIADFGQACFYMNCPPNLNYQTPADPMQ

TSVSYIASRFYRAPELILGCEQYTGAIDVWAAGCVIAEMLRMGEVLFEGMTGTGQIIPIIQLLGKPTQSDLSSFQHTAPVPTSLTKPIIKLE--DQLPKT
  .. .. | |||||| .|  .|....|.|..||..||... |  .| | | . |.  |...|| |.  . ..          ..|.  |.   .  || 
QYSTQVSTRWYRAPELLFGSKCYDTGVDIWSFGCIYAEWFQ-GKPIFQGRTEIEQMHHIFKMLGTPCEDMWPDWRYMPDYCKIFFKYKQKFHWWNRFPKC

TNSKLIALLKQIFVYNPTKRITAAQCLQHPYF
.    . .. |  .|.| .| .. . ||||.|
KHASENNCEFQMVMYQPYNRWKCMEILQHPWF
Kinase 95695.m00061.AA MAPK 139-321 34 8.2e-50 170.37 In-house 118-328 (328) Show / Hide 
Range on Protein: 139-321
Range on HMM: 118-328/328
Sequence Identity: 34% (73 aa)

KILAYQIFAG--LRYLHAKGIVHRDIKPENIMFSPVTGKLKITDFGSAKVIKPGDTSV---------------SYIASRFYRAPELILG--CEQYTGAID
. . |||  |  | |.|  ...|||.||.||      . ||| ||| | .| | ..                  |.| |.|||||..|.     || |.|
QYFMYQILRGLKLKYIHSANVIHRDLKPSNILVN-ENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAPEIMLNWIWMHYTKAVD

VWAAGCVIAEMLRMGEVLFEGMTGTGQIIPIIQLLGKPTQSDLSSFQ---HTAPVPTSL----TKPIIKLEDQLPK---TTNSKLIALLKQIFVYNPTKR
.|..||  ||||. . .|| |     |.  |...||.|.. ...  .   | . .  ||     .| . .|. .|.    .|.. | ||..  | .| ||
MWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQAIDLLEKMLVFDPDKR

ITAAQCLQHPYF
||....||||||
ITVEEALQHPYF
Kinase 95695.m00061.AA Ciliate-E2 37-321 18 8.9e-49 165.55 In-house 1-365 (365) Show / Hide 
Range on Protein: 37-321
Range on HMM: 1-365/365
Sequence Identity: 18% (79 aa)

YLGYRLIGSGTFGSVYKART------------------------IAGKVVAIKSV-KQDPQYKNRELEILK----------------ILHSRYCIKLKDH
|   ..||.|.||||||..                          ..| .|.|.. |.. .....|. |..                .| . . ||....
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YF--TRKNNGKDVYLNIVMDYFPYTVHSYTMKLR----------------DQQKRIGNTLLK-------ILAYQIFAGLRYLHAKG-IVHRDIKPENIMF
.   ...|      . .||.|. .    . .| .                 . |.|   .|.         . .|  .|.||| |. |.|||||||||.|
FQEKDDNN------IYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF

SPVTGKLKITDFGSAKVIKPG-------------------DTSVSYIA-------------SRFYRAPELILGCE--------QYTGAIDVWAAGCVIAE
      .||.||| .| ...                    ... .|..             .  | ||| . | .        .|. ..|.|..|... |
------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYE

MLRMGEVLFEGMTGTGQIIPIIQLLGKPTQSDLSSFQHTAPVPTSLTKPIIKLED---QLP------------------KTTNSKLIALLKQ----IFVY
|| .|.  |                                        ... ..   ..|                  |    . . |.|.    ....
ML-FGKPPF----------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQK

NPTKRIT-AAQCLQHPYF
.| |||| . |.|.||.|
DPEKRITGWEQILNHPWF
Kinase 95695.m00061.AA CDKL 137-321 35 1.1e-47 161.15 In-house 99-286 (286) Show / Hide 
Range on Protein: 137-321
Range on HMM: 99-286/286
Sequence Identity: 35% (67 aa)

LLKILAYQIFAGLRYLHAKGIVHRDIKPENIMFSPVTGKLKITDFGSAKVIK-PGDTSVSYIASRFYRAPELILGCEQYTGAIDVWAAGCVIAEMLRMGE
...   .||  .. ..|   ..|||||||||  .|  | .|. ||| |. .. ||.    | | | |||||| .|  ||  ..|.||.|||.|||. .|.
VVRKYMWQILKAINFCHKHNCIHRDIKPENILITPKNGQVKLCDFGFARMLAKPGEIYTDYVATRWYRAPELLVGDTQYGKPVDIWAIGCVMAEMI-DGQ

VLFEGMTGTGQIIPIIQLLGKPTQSDLSSFQHTAPVPTSLTKPIIK----LEDQLPKTTNSKLIALLKQIFVYNPTKRITAAQCLQHPYF
 |. |     |   |.. ||. ..   . |  . |.   .. |.|.    ||. .|.  |.|.. ..|. .  .|..|.|..|...||||
PLWPGQSDIDQLYHIQKCLGPLIPRHQEIFS-KNPFFHGMKFPEIEHMEPLEKRYPNKSNKKALDFMKKCLHMDPDERMTCEQLMHHPYF
Kinase 95695.m00061.AA RCK 143-321 34 8.8e-47 146.3 In-house 112-298 (298) Show / Hide 
Range on Protein: 143-321
Range on HMM: 112-298/298
Sequence Identity: 34% (66 aa)

YQIFAGLRYLHAKGIVHRDIKPENIMFSPV--------TGKLKITDFGSAKVIKPGD--TSVSYIASRFYRAPELILGCEQYTGAIDVWAAGCVIAEMLR
|||..|| ..| .|. |||.|||||| ..         .. .||.|||... |      |   |. .| |||||..| | .|.  .|.|| ||...|   
YQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPPYT--DYVSTRWYRAPECLLRCTYYNSPMDIWAVGCIMYELYM

MGEVLFEGMTGTGQIIPIIQLLGKPTQSDLSSFQHTAPVP--TSLTKPIIKLEDQLPKTTNSKLIALLKQIFVYNPTKRITAAQCLQHPYF
.   || |     ||  |.. .| |.. |.. ..  |     .   .. ..|.  .|   .. .| |..    ..| |||||.|.||||||
L-RPLFPGSSEIDQIFKICKVMGTPNKKDWPDGYKLASQMNFNFPQCKGMPLKQLIPN-CSQDCIELMEKMLQWDPQKRITAQQALQHPYF
Kinase 95695.m00061.AA DYRK 142-321 31 1.5e-43 151.01 In-house 109-320 (320) Show / Hide 
Range on Protein: 142-321
Range on HMM: 109-320/320
Sequence Identity: 31% (69 aa)

AYQIFAGLRYLHAK-GIVHRDIKPENIMFSP--VTGKLKITDFGSAKVIKPGDTSVSYIASRFYRAPELILGCEQYTGAIDVWAAGCVIAEMLRMGEVLF
|.||. .|..|| .  |.| |.||||||         .|. ||||.  ..   .  .|| |||||||| |||| .|  |||.|  ||..||..  |..||
AQQILTCLKFLHKNENIIHCDLKPENIMLKQPRNKSTIKVIDFGSSCFEHQ--RIYTYIQSRFYRAPEVILGC-PYCYAIDMWSLGCILAELF-TGWPLF

EGMTGTGQIIPIIQLLGKPTQSDLSS---------FQH------------TAPVPTSLT---KPIIKLEDQLPKTTN---------SKLIALLKQIFVYN
 | .   |.  |...||.|..  ...         |                . ... |   .|. . .  .|...|         .... ..|. ....
PGENEYDQLACIMEVLGMPPKWMIDKGRCRRKHKFFDCFMYCECDEWTKQNKITDHYMTPKCHPTKRGQRRPPGRRNWDPRHQCDDHQFKDFIKKCLQWD

PTKRITAAQCLQHPYF
|.||||..| |||| |
PHKRITPSQALQHPWF
Kinase 95695.m00061.AA CAMK 144-226 22 4e-30 93.68 In-house 187-323 (425) Show / Hide 
Range on Protein: 144-226
Range on HMM: 187-323/425
Sequence Identity: 22% (31 aa)

QIFAGLRYLHAKGIVHRDIKPENIMFSPVT----------------GKLKITDFGSAKVIKP------------------------GDTSVSYIASRFYR
||  ...|.| ..|||||.|||||...                   ...||.||| |....|                        |.    .  .  | 
QICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYM

A-PELILG-------------CEQYTGAIDVWAAGCV
| ||...|              . |. ..|.|..|..
AAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVI
Kinase 95695.m00061.AA CAMK 42-114 17 1.8e-14 42.35 In-house 1-141 (425) Show / Hide 
Range on Protein: 42-114
Range on HMM: 1-141/425
Sequence Identity: 17% (25 aa)

LIGSGTFGSVYKARTI-AG------------KVVAIKSVKQD-----------------------------PQYKN---RELEILKI-------LHSRYC
 .|.|.|| |.... .  .            . |||| .. .                             |. .    ||.||.|        |. .  
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKLKDHYFTRK---------NNGK-----DVYLNIVM---DY
||| ..| ...         .  |     | .. .||   .|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEY
Kinase 95695.m00061.AA TyrKc 37-321 21 1.2e-12 -17.95 SMART 1-280 (280) Show / Hide 
Range on Protein: 37-321
Range on HMM: 1-280/280
Sequence Identity: 21% (69 aa)

YLGYRLIGSGTFGSVYKARTIAGKVVAIKSVKQDPQYKN--RELEILKIL--HSRYCIKLKDHYFTRKNNG-----KDVYLNIVMDYFPY-TVHSYTMKL
    . .|.| || |||.. .    ||.|..| |   .   ||..|.. |  |    ..|  .   ..  .     . ..  ||| | |.   ..|  | 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRL--YGVCTQQGRNFMYIEPLM--IVMEYMPHGDLKDYLRKH

RDQQKRIGNTLLKILAYQIFAGLRYLHAKGIVHRDIKPENIMFSPVTGKLKITDFGSAKVIKPGDTS----VSYIA-----SR-----FYRAPELILGCE
|..   . .  |   ..|| .| .||| |...|||.   |.. .      ||.||| .. |. .|..      | .     ..        ||| |   .
RPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NY

Q-YTGAIDVWAAGCVIAEMLRMGEVLFEG-----MTGTGQIIPIIQLLGKPTQSDL----SSFQHTAPVPTSLTKPIIKLEDQLPKTTNSKLIALLKQIF
  .| . |||. | .. |..  |.   .|     |. . ..|  ..  . . | .     |                         .  ...  . ||  
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQ-EVIEYVKQGYRMPQPPNDYPMS----------------------F-VCCPDEMYQIMKQCW

VYNPTKRITAAQCLQHPYF
 ..| .| | ...  | .|
HEDPEDRPTFSEI--HECF
Kinase 95695.m00061.AA CAMK 297-321 40 2.2e-10 28.91 In-house 401-425 (425) Show / Hide 
Range on Protein: 297-321
Range on HMM: 401-425/425
Sequence Identity: 40% (10 aa)

LLKQIFVYNPTKRITAAQCLQHPYF
|.... ...|.||.|..|||.|| .
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 95695.m00061.AA DYRK 37-95 26 3e-06 19.51 In-house 1-69 (320) Show / Hide 
Range on Protein: 37-95
Range on HMM: 1-69/320
Sequence Identity: 26% (18 aa)

YLGYRLIGSGTFGSVYKARTIAGK-VVAIKSVKQDPQYKN---RELEILKILHSR------YCIKLKDH
|  .  ||.|.|| | |..   ..  |||| ..  . . .   .|..||. |.        .|....|.
YEILEYIGKGSFGQVVKCWDHKTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQDPDDKYHCVHMYDY
Kinase 95695.m00061.AA RCK 37-69 44 3e-06 15.51 In-house 1-34 (298) Show / Hide 
Range on Protein: 37-69
Range on HMM: 1-34/298
Sequence Identity: 44% (15 aa)

YLGYRLIGSGTFGSVYKARTI-AGKVVAIKSVKQ
|   . .| ||.|.| ||. .  |..||||  ||
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMKQ
Kinase 95695.m00061.AA MAPK 37-65 36 0.000103 11.97 In-house 1-36 (328) Show / Hide 
Range on Protein: 37-65
Range on HMM: 1-36/328
Sequence Identity: 36% (13 aa)

YLGYRLIGSGTFGSVYKARTI-------AGKVVAIK
|   . ||.| .| | .|.          || ||||
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIK
Kinase 95695.m00061.AA Pkinase_Tyr 41-70 31 0.000899 13.4 Pfam 5-39 (270) Show / Hide 
Range on Protein: 41-70
Range on HMM: 5-39/270
Sequence Identity: 31% (11 aa)

RLIGSGTFGSVYKARTI-----AGKVVAIKSVKQD
. .|.| ||.|||..        .  ||.|..|..
KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEG
Kinase 95695.m00061.AA Pkinase_Tyr 142-162 42 0.003207 11.53 Pfam 117-137 (270) Show / Hide 
Range on Protein: 142-162
Range on HMM: 117-137/270
Sequence Identity: 42% (9 aa)

AYQIFAGLRYLHAKGIVHRDI
..|| .|. ||..|...|||.
CWQIAKGMEYLESKNCIHRDL