Gene 81238.m00170 (T.vaginalis)

81238.m00170

Species: T.vaginalis
Alias: TvagK0008, 81238.m00170
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
81238.m00170.AA Protein None 344 None Fasta, JSON
81238.m00170.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 81238.m00170.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 81238.m00170.AA MARK 9-260 35 3.8e-82 268.31 In-house 1-262 (262) Show / Hide 
Range on Protein: 9-260
Range on HMM: 1-262/262
Sequence Identity: 35% (93 aa)

YLIQNEIGRGATSRVHTAINTITNKKLCVKILEKSSLETAEDFEFFRREVAIISSLAHKNIVRYHDLME--DECY-YYLFQEFCPGVTLTKFLEKN--NL
| .  .|| |. . |  |... |..| ..||.|| .|   . .. ..||..| ..| |.||..... .|  .|    ||  | ..|  |  ....     
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LSDRLLQLIFRQIFSALAYMHKLHVGHRDLKPDNILIDQEC--NIKIVDFGLSTDD-NTKLRTTFCGSLAFAPPECIKREPYNAAQADIWSLGVMLYMAA
|. ..   ||||| ||. |.|. .. |||.||.|||||..   |||| |||.|.   . .. .||||......|| ....||..  .||||||| ||   
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

TGKLPWR--TTNLVQIMKQITSGNFSIPCNVSNNVRNIIMMCMNQNPSQRPTADELLTYPIV
.|..|..  | ......|.|..|...|||.||   ||.|   .. ||..|||..|..  | .
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
S_TKc 81238.m00170.AA S_TKc 9-260 29 4.1e-82 280.02 SMART 1-231 (231) Show / Hide 
Range on Protein: 9-260
Range on HMM: 1-231/231
Sequence Identity: 29% (79 aa)

YLIQNEIGRGATSRVHTAINTITNKKLCVKILEKSSLETAEDFEFFRREVAIISSLAHKNIVRYHDLMEDECYYYLFQEFCPG--VTLTKFLEKNNL---
| | ..||.|| ..|. .... |...  .||.           | .|||..| ..  |.|||...| ..|  ..|.. |.|.|   .| ....|..    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LSDRLLQLIFRQIFSALAYMHKLHVGHRDLKPDNILIDQECNIKIVDFGLSTDDNTKLRTTFCGSLAFAPPECIKREPYNAAQADIWSLGVMLYMAA
   ..    . ...||..||.|.|.... ||||||.|||.|.  .||| ||||..       |||||.. . .|| .   .|. . .|.||.|..||  .
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

TGKLPWRTTNLVQIMKQITSGNFSIPCNVSNNVRNIIMMCMNQNPSQRPTADELLT-------YPIV
.|. |..  .. ...|.|           |  ....|. |.. .|..|||| |.|.        | .
CGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 81238.m00170.AA CAMK 14-255 19 1.3e-81 262.58 In-house 1-420 (425) Show / Hide 
Range on Protein: 14-255
Range on HMM: 1-420/425
Sequence Identity: 19% (81 aa)

EIGRGATSRVHTAINTITN------------KKLCVKILEKSSLE-------------------------TAEDFEFFRREVAIISSLA-------HKNI
..|||. . |. .|.. |.            .|  .||..|. |                          ...| ...|||..| ..|        |.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRYHDLMED-------------------ECYYYLFQ---EFCPGV----TLTKFLEKNNL---------------LSDRLLQLIFRQIFSALAYMHKLHV
.. .. .||                   . ..|..    |.|.|      |  .. ..                 .. |  . .|||| ||..|.|....
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

GHRDLKPDNILIDQE-----------------CNIKIVDFGLS--TDDN-----------------------TKLRTTFCGSLAFAP-PECIKR------
 ||||||.|||.|.                  .||||.|||..   |..                       ... .||||...... || ...      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------EPYNAAQADIWSLGVMLYMAATGKLPWRTT-------------NLVQIMKQITSGNFS-IPCN---------------VSNN--------VRN
       .||   ..|.||.||.||.  .|..|..               |. .....|..|... .|                 .|..        ...
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

IIMMCMNQNPSQRPTADELL
 |  ... .|..|.|... |
LIRKMLQVDPEKRMTIEQCL
Kinase 81238.m00170.AA CAMKL 9-255 28 9.2e-80 254.2 In-house 1-292 (297) Show / Hide 
Range on Protein: 9-255
Range on HMM: 1-292/297
Sequence Identity: 28% (85 aa)

YLIQNEIGRGATSRVHTAIN-TITNKKLCVKILE--KSSLETAEDFEFF----------RREVAIISSLA---HKNIVRYHDLMEDECY------YYLFQ
| |  ..|.|. . |  |..  .|..|  .||..  | ....  .  .           |||..| ..|    |.||.. .. .|.. .      .||. 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EFCPGVT--LTKFLEKN----NLLSDRLLQLIFRQIFSALAYMHKLHVGHRDLKPDNILIDQEC--NIKIVDFGLSTD-DN-----TKLRTTFCGSLAFA
| |.|    |  ...|.      .. .  . .|||| ||..|.|.... |||.||.|||.|.    ||||.|||.|.  ..      .. .|||||....
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

PPECIKR--EPYNAAQADIWSLGVMLYMAATGKLPWRTT--------NLVQIMKQITSGNFSIP--CNVSNNVRNIIMMCMNQNPSQRPTADELL
.|| ...  .||.. ..||||.||.||.  .|.||..          |    ...| .| . .|  . ||  .|..|   .. ||..|||.....
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIM
Kinase 81238.m00170.AA Pkinase 9-260 28 6.5e-70 243.37 Pfam 1-293 (293) Show / Hide 
Range on Protein: 9-260
Range on HMM: 1-293/293
Sequence Identity: 28% (83 aa)

YLIQNEIGRGATSRVHTAINTITNKKLCVKILEKSSLETAEDFEFFR-REVAIISSLAHKNIVRYHDLMEDECYYYLFQEFCPGV----TLTKFLE--KN
| |   ||.|. ..|  ...  |.|. .|||..|.. .  .| . .| .|..|  .| |.||||..| .||. ..|. .|.|.|      |  ...  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NLL--SDRLLQLIFRQIFSALAYMHKLHVGHRDLKPDNILIDQECNI----KIVDFGLST---DDNTKLRTTFCGSLAFAPPECIKREPYNAAQADIWSL
. .  |.. .. ...||...|.|.|.  . ||||||.|||||....|    || ||||.      |    |||||.. ...|| |.  .|    .|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVMLYMAATGKLPWRTT------NLVQIMKQITSGNFSIPCNVS---------------------NNVRNIIMMCMNQNPSQRPTADELLTYPIV
|..||  ..|..|..        .  |....| .. .. ..  .                      . . .|  | ...|..||||...|  | .
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 81238.m00170.AA AMPK 9-260 32 1.1e-65 194.06 In-house 1-254 (254) Show / Hide 
Range on Protein: 9-260
Range on HMM: 1-254/254
Sequence Identity: 32% (84 aa)

YLIQNEIGRGATSRVHTAINTITNKKLCVKILEKSSLETAEDFEFFRREVAIISSLAHKNIVRYHDLM-EDECYYYLFQEFCPGVTLTKFLEKNNLLSDR
|.|.  ||.|.   |  .. ..|..|  .|||.|  .   .. |  .||. |  .. | .|..  .   | .   ... |. .|  |  .  |.. |. |
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

LLQLIFRQIFSALAYMHKLHVGHRDLKPDNILIDQECNIKIVDFGLS--TDDNTKLRTTFCGSLAFAPPECIKREPYNAAQADIWSLGVMLYMAATGKLP
  .  | || |.. |.|.. . |||||| |.|.|.. ||||||||||    |. .|.|  |||   | || |   .|.  . |||| || ||    |.||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTA-CGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLP

WRTTNLVQIMKQITSGNFSIPCNVSNNVRNIIMMCMNQNPSQRPTADELLTYPIV
    |  .  | |..| ..|| ..|......|.   . .| .| | ...   |  
FDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 81238.m00170.AA Ciliate-E2 9-260 20 5.2e-61 208.17 In-house 1-365 (365) Show / Hide 
Range on Protein: 9-260
Range on HMM: 1-365/365
Sequence Identity: 20% (77 aa)

YLIQNEIGRGATSRVHTA--INT---------------------ITNKKLCVKILEKSSLETAEDFEFFRREVA----------IISSLAHKNIVRYHDL
| ... ||.|. . |  .  ...                      ..|.  .||..|. .|  .  .   ||.           | ..| |.||..... 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

ME--DECYYYLFQEFCPGVTLTKFLEKNNLLS-----------DRLLQLIFRQIFS---------------ALAYMHKLH-VGHRDLKPDNILIDQECNI
 .  |. ..||  |.| | .| .....|.. .           ..  . |..||..               || |.|. . . |||.||.|||.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIVDFGLSTDDNTK---------------------------------LRTTFCGSLAFAPPECIKREPYNA--------AQADIWSLGVMLYMAATGKLP
||.|||||.. ...                                 .  |.||.. . .|| .....|.          ..|||||||.||.  .||.|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

WRTTNLVQIMKQITSGNFSIPCN------------------VSNNVRNIIMM----CMNQNPSQRPT-ADELLTYPIV
.        ..||  .....||.                  .|... ..|      ... .|..|.| ....|  |. 
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 81238.m00170.AA ULK 9-260 23 2.9e-58 199.86 In-house 1-329 (329) Show / Hide 
Range on Protein: 9-260
Range on HMM: 1-329/329
Sequence Identity: 23% (76 aa)

YLIQNEIGRGATSRVHTAINTIT----NKKLCVKILEKSS-LETAED------FEFFRREVAIISSLA----HKN----IVRYHDLMEDE--CYYYLFQE
| . ...| |.  .|. ..| .|    |.|  .|...|..  .   .       .....|. |.  |     |||    ||...|  |.   ...|...|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FCPGVTLTKFLEKNNL----------LSDRLLQLIFRQIFSALAYMHKLHVGHRDLKPDNILIDQECN------------IKIVDFGLSTD-DNT----K
.|.| .| ....||.           ||    . .|.|| ... ..||  . |||.||.||||.                .|| |||..   ||     .
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

LRTTFC------GSLAFAPPECIK----REPYNAAQADIWSLGVMLYMAATGKLP---WRTTNLV-QIMKQ-----------ITSGNFSIP-----CNVS
. .|.       |.  .  |. ..    ..||. . .||||||...|   .|| |   |  . .. ||...           | . .. .|      ..|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

NNVRNIIMMCMNQNPSQRPTADELLTYPIV
......|  ..  ....| . .||.  |..
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 81238.m00170.AA ULK 9-260 22 2.1e-57 197.05 In-house 1-324 (324) Show / Hide 
Range on Protein: 9-260
Range on HMM: 1-324/324
Sequence Identity: 22% (73 aa)

YLIQNEIGRGATS-RVHTAINTIT---NKKLCVKILEKSSL-ETAED------FEFFRREVAIISSLA---HKN--IVRYHDLMEDE--CYYYLFQEFCP
| . ...| |.    |. ..| .|   |..  .|. .|... .   .       .....|. |.  |    |.|  ||...|  |.    ..|...|.|.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GVTLTKFLEKNNL---------LSDRLLQLIFRQIFSALAYMHKLHVGHRDLKPDNILIDQECN------------IKIVDFGLSTD-DN----TKLRTT
| .| ....||.          ||    . .|.|| ... ..||  . |||.||.||||                 .|| |||..   ||      ...|
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

FC------GSLAFAPPECIK----REPYNAAQADIWSLGVMLYMAATGKLP---WRTTNLV-------------QIMKQITSGNFSIPC---NVSNNVRN
..      |.  .  |. ..    ..||. . .||||||...|   .|| |   |  ....             ||. . .  .| .|.   ..|.....
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

IIMMCMNQNPSQRPTADELLTYPIV
.|. ..  ....| . .|..  |..
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 81238.m00170.AA STE 9-260 21 2.2e-56 193.61 In-house 1-359 (359) Show / Hide 
Range on Protein: 9-260
Range on HMM: 1-359/359
Sequence Identity: 21% (78 aa)

YLIQNEIGRGATSRVHTAINT------ITNKK---------LCVKILEKSS------------LETA--EDFEFFRREVAIISSLA--HKNIVRYHDLME
. .. .||.||.  |..|.|        |...           .|......            ||.   |... . .|. | . .   |.|||.|..  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DEC-------YYYLFQEFCPGVTLTKFLEKN----NLLS----------DRLLQLIFRQIFSA-LAYMHKLHVGHRDLKPDNILIDQECNIKIVDFGLST
.|.       . ... |...| .|.......    . |.            ..  | |||  . |.| |..|. |||.||.|||.     .|..|||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

DDNT------------------KLRTTFCGSLAFAPPECIKR------EPYNAAQADIWSLGVMLYMAATGKLPWRTTNLVQIMKQITSGN---------
  .                   . |.||.|.  .  || |..       .|. ...|||||| ..   |||| || . .  . | .|. ..         
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYD-TKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

----FSIP----------------------CNVSNNVRNIIMMCMNQNPSQRPTADELLT--YPIV
    . .|                       ..| . .. |  | . .|..||||..||    | .
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 81238.m00170.AA Ciliate-E2-Unclassified 9-260 20 8.4e-56 191.71 In-house 1-352 (352) Show / Hide 
Range on Protein: 9-260
Range on HMM: 1-352/352
Sequence Identity: 20% (72 aa)

YLIQNEIGRGATSRVHTAINTITNKK-----LCVKILEKSSLETAEDFEFFRREVAII------------------SSLAHKNIVRYHDLMEDECYYYLF
| |.  ||.|. . |. ...  ....     .....  |. .   .| |. . . ..                   ... | .||....  .|. . |. 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

QEFCPGVTLTKFLEKN-----------------NLLSDRLLQ-----LIFRQIFSALAYMHKLH-VGHRDLKPDNILIDQEC---NIKIVDFGLST----
 |.|.| .| ....|.                 . ....  .      .|.|| ..| |.|. . . |||.||.|||.|...   .||| |||.|     
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

-----DDN--------TKLRTTFCGSLAFA----PPECIKREPYNA---AQADIWSLGVMLYMAATGKLPWRTTNLVQ----------------IMKQIT
     ...         .. .||||.. .     .||..... |.     ..||||||| ||   .|..|   .|  |                . ..| 
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

SGNFSIPC--------NVSNNVRNIIM----MCMNQNPSQRPTADELLTYPIV
 .|...|.        ..|... ..|      ... ||..|.|....|  |. 
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 81238.m00170.AA RSK 11-255 26 3e-54 186.54 In-house 1-273 (278) Show / Hide 
Range on Protein: 11-255
Range on HMM: 1-273/278
Sequence Identity: 26% (73 aa)

IQNE--IGRGATSRVHTAINTITNKKLCVKILEKSSLETAE-DFEFFRREVAIISSLA-HKNIVRYHDLMEDECYYYLFQEFCPGVTLTKFLEKNNL---
..    .| |. . ..  ..  |..   .|.|.|. . ... | .  ..|. | .    |..||..|.  ..|.. ||  |.|.|  |.. |.|      
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LSDRLLQLIFRQIFSALAYMHKLHVGHRDLKPDNILIDQ---ECNIKIVDFGLSTD---DNTKLRTTFCGSLAFAPPECIK---REP-YNAAQADIWSLG
.| .  . ....| .|. ..|.... ||||||.||| |.   |  ||..|||..     |....  |||.......|| .|   ..  ...| .|.||||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKA-CDWWSLG

VMLYMAATGKLPWRT---TNLVQIMKQITSGN--FSIP--CNVSNNVRNIIMMCMNQNPSQRPT-----ADELL
| .|.  ||..| .     |  .|||.| .|.  ...|   ..|.. ...| ...  .|..|..     |.|..
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIK
Kinase 81238.m00170.AA TyrKc 9-260 21 2.3e-15 25.76 SMART 1-280 (280) Show / Hide 
Range on Protein: 9-260
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

YLIQNEIGRGATSRVHTAINTITNKKLCVKILEKSSLETAEDFEFFRREVAIISSL--AHKNIVRYHDLMEDE-------CYYYLFQEFCPGVTLTKFLE
     ..|.||  .|. .. .       ..   |.  | |   | |.||  | ..|   |.|||| .    ..         ...  |..|.  | ..| 
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KNNL-LSDRLLQLIFRQIFSALAYMHKLHVGHRDLKPDNILIDQECNIKIVDFGLSTDDNTK---------LRTTF--CGS----LAFAPPECIKREPYN
|.   |. . |  .  || .  .| |. .. ||||   |.|.. .  .|| ||||| |   .          |..   .|     .   .||||.   ..
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

AAQADIWSLGVMLY-MAATGKLPWRT-----TNLVQIMKQITSGNFSIPCNV---------SNNVRNIIMMCMNQNPSQRPTADELLTYPIV
 .  |.|| ||... .   |. |.        .  ...... .|.   .            .  . .|. .| . .|..|||  |.  . . 
TK-SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 81238.m00170.AA Pkinase_Tyr 54-156 30 7.8e-07 23.77 Pfam 50-160 (270) Show / Hide 
Range on Protein: 54-156
Range on HMM: 50-160/270
Sequence Identity: 30% (34 aa)

FRREVAIISSL-AHKNIVRYHDLME-DECY--YYLFQEFCPGVTLTKFLEK----NNLLSDRLLQLIFRQIFSALAYMHKLHVGHRDLKPDNILIDQECN
| ||..| ..|  |.||||..     ..    .|.  |..|.  | ..| |    .. |.   |  . .|| ....| .  .  ||||   |.|.. .  
FMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNV

IKIVDFGLSTD
.|| ||||. |
VKICDFGLARD
Kinase 81238.m00170.AA Pkinase_Tyr 186-255 24 0.000153 16.01 Pfam 194-267 (270) Show / Hide 
Range on Protein: 186-255
Range on HMM: 194-267/270
Sequence Identity: 24% (18 aa)

QADIWSLGVMLYMAAT-GKLP-WRTTNLVQIMKQI-TSGNFSIPCNV--SNNVRNIIMMCMNQNPSQRPTADELL
. |.|| || ..   | |. | .      .....|  .|.   ||    .  . .....|....|..|||  |..
KSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYR-MPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIH