Gene 94222.m00135 (T.vaginalis)

94222.m00135

Species: T.vaginalis
Alias: 94222.m00135, TvagK0802
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: LKB

Sequence

Name Sequence Type Origin Length Description Download
94222.m00135.AA Protein None 349 None Fasta, JSON
94222.m00135.kin_dom Protein Kinase Domain None 261 None Fasta, JSON

Protein domain

Protein domains of 94222.m00135.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 94222.m00135.AA S_TKc 26-286 28 6.8e-74 252.71 SMART 1-231 (231) Show / Hide 
Range on Protein: 26-286
Range on HMM: 1-231/231
Sequence Identity: 28% (78 aa)

YNLLKTIGQGANCKVVLIQDSLNRKYYAAKVFKLAKTYPNAKTSLPLEREVRIMKKIHHENIVNFREVLFAPEKNAFYLIMEWGNC--GSLQNLIDTKIK
| .|..||.||  || . ..    ...| |. |             ..||..|.|| ||.|||.. .|      . .|..||  .   |.|  .|. . .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGR

------IAEKTIASIFRQLVNGLSYLHSQGFVHQDIKPSNVLLFSDGTAKIGDFGIGHSFQSAETVVGTPAYQAPEIFDDSYDDLTDLPALDPAKEDVWS
      . | .......|....| |.||.|..| |.||.|.|| .  . ||.|||.   .    |..||| | |||..             ...| |.||
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---TTFCGTPWYMAPEVL-----------GYGKCKCDWWS

LGVTLFETLFGKLPFTGENVYEIARTIRKIGLVLPNNISGPLSDLLFGMLNPDPTKRLSLDEVKE-------SSFF
.|..|.| | |. ||      .......|||       | .. |.. ..|. ||.||..  |. .         .|
CGCILYEMLCGYPPFP-----QMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 94222.m00135.AA CAMK 31-286 19 1.2e-66 213.5 In-house 1-425 (425) Show / Hide 
Range on Protein: 31-286
Range on HMM: 1-425/425
Sequence Identity: 19% (84 aa)

TIGQGANCKVVLIQDSLNR------------KYYAAKVFKLAKTYP------------------------NAKTSLPLEREVRIMKK-------IHHENI
|.|.|. .|| | .. ..             . .|.|. .  |                           ..|.   ..||..||||       ..|.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VNFREVLFAPE-----------------KNAFYLIM---EWGNCG----SLQNLIDTK---------------IKIAEKTIASIFRQLVNGLSYLHSQGF
... ||   |.                 .. .|..|   |    |     | . |  .                .. |.  . .|||.. .. |.||.. 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHQDIKPSNVLLFSD-----------------GTAKIGDFGIGHSFQS---------------------------AETVVGTPAYQA-PEIFDD-SYDDL
|| |.|| |.|| ..                 .. || |||    |..                            .|..|||.| | ||..   . .. 
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

TDLPAL--------DPAKEDVWSLGVTLFETLFGKLPFTGE-------------NVYEIARTIRKIGLV-LPNNISG-----------------------
.             .. | |.||.|| |.  | |..|| |.             | ||. . |.|      |  .|.                       
Q----NATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQ

PLSDLLFGMLNPDPTKRLSLDEVKESSFF
   ||. .||..||.||........  ..
ECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Pkinase 94222.m00135.AA Pkinase 26-286 24 2.5e-65 228.13 Pfam 1-293 (293) Show / Hide 
Range on Protein: 26-286
Range on HMM: 1-293/293
Sequence Identity: 24% (77 aa)

YNLLKTIGQGANCKVVLIQDSLNRKYYAAKVFKLAKTYPNAKTS---LPLEREVRIMKKIHHENIVNFREVLFAPEKNAFYLIMEWGNCG----SLQNLI
| ....||.|.  .| . ..  ..| .| |..|. .. .. . .   |   .|..|||...|.||| ....     |.  |..||. ..|    .|  .|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL---SEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYI

D--TKIKI--AEKTIASIFRQLVNGLSYLHSQGFVHQDIKPSNVLLFSDGTA----KIGDFGI-----GHSFQSAETVVGTPAYQAPEIFDDSYDDLTDL
    . ..   |... ....|.. || |.||.|..| |.||.|.|. ..|.     ||.|||.       . . . |..||| | |||.          .
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEV---------IR

-PALDPAKEDVWSLGVTLFETLFGKLPFTGE----NVYEIARTIRKIGL-------------------------VLPNNISGPLSDLLFGMLNPDPTKRL
    .. | |.||.|..|.| |.|..|| |.    | ..    |..|.                          ..  |.| .. |.. ..|..||.||.
GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLCKDPKKRP

SLDEVKESSFF
. ...... .|
TAEQILQHPWF
Kinase 94222.m00135.AA CAMKK 26-286 23 2.7e-65 206.05 In-house 1-396 (396) Show / Hide 
Range on Protein: 26-286
Range on HMM: 1-396/396
Sequence Identity: 23% (95 aa)

YNLLKTIGQGANCKVVLIQDSLN-RKYYAAKVFK-------LAK------------TYPNAKTS--LP-----LEREVRIMKKIHHENIVNFREVLFAPE
| |.|.||||.  || |  .. .  |.|| |.|.       | |            |..|.. .  ..     ...|. ||||..|.|||   ||.  |.
YELMKEIGQGQFGKVKLAYNEYDTQKHYAIKIFNKKYVFKKLKKKQQFYRDPPKRMTNMNQNGEMQMMNPFDCVYQEIAIMKKCNHPNIVKLYEVIDDPQ

KNAFYLI-MEWGNCGSLQNLI--DTKIK-----------------------IAEKT---------------------IASIFRQLVNGLSYLH-SQG---
 .  |.. ||. . |.....   .....                       . |.                        ..||. . || ||| .|.   
NDKIYMVQMEYCERGQIMWWPYWKQDYQPNWPYQYTELYSNRQYQNKDFSIMSEQQSISEFINQVVKQDQYFIHEDYAWKYFRDCIKGLEYLHNYQKACS

----------------FVHQDIKPSNVLLFSDG---TAKIGDFGIGHSF-QSAET--------------VVGTPAYQAPEIFDDSYDDL-----------
                 .| ||||.| |. ..|   ..|| |||. |.| .. .|               .||||..||| .... .             
YIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTPAFMAPELCSKENQKENYNGYKYRFRF

-TDLPALDPAKEDVWSLGVTLFETLFGKLPFTGENVYEIAR---TIRKIGLVLPN-------------NISGPLSDLLFGMLNPDPTKRLSLDEVKESSF
 .. .|.     |.|.|||||.  .|||.|| ..|  .. .    | .  .. |              .||  | ||...||. .||||......|.  .
IYCGKAA-----DIWALGVTLYCFVFGKCPFWHNNLMQLHHNYMKIKNDPIKFPENKEMLNNVSIYCPEISEDLKDLIKRMLEKNPTKRITIPQIKVHPW

F
.
V
Kinase 94222.m00135.AA LKB 74-286 35 1.2e-59 175.7 In-house 49-265 (265) Show / Hide 
Range on Protein: 74-286
Range on HMM: 49-265/265
Sequence Identity: 35% (79 aa)

REVRIMKKIHHENIVNFREVLFAPEKNAFYLIMEWGNCGSLQNLIDT--KIKIAEKTIASIFRQLVNGLSYLHSQGFVHQDIKPSNVLLFSDGTAKIGDF
.|. |.|..|| ...   .|.  .||   |..||   || .|...|   . ..       .|.||. |. |||||. || ||||.| ||  |.| || ||
KEIQILKRMHHRHVIQLIDVFYNEEKQKMYMVMEYCVCGTMQEMLDMQPCKRMPIWQAHFYFCQLCDGCEYLHSQRVVHKDIKPGNLLLTHDNTLKICDF

GIG---HSFQSAE---TVVGTPAYQAPEIFDDSYDDLTDLPALDPAKEDVWSLGVTLFETLFGKLPFTGENVYEIARTIRKIGLVLPN--NISGPLSDLL
|.    | ||  .   |. |.||.| ||.     |        .. | |.|| ||||.    || || | |.|     | |  . .|.   .  .|..|.
GVAEQLHHFQRDDCCTTSQGSPAFQPPECANGNHD------TFSGFKVDIWSMGVTLYNMTTGKYPFEGDNMYKLFENIGKCQWEMPCWYDCDKDLQNLI

FGMLNPDPTKRLSLDEVKESSFF
 |||  |. ||.|. .... . |
KGMLQYDHNKRFSCHQIMHHPWF
Kinase 94222.m00135.AA Ciliate-E2 26-286 23 8.2e-55 186.58 In-house 1-365 (365) Show / Hide 
Range on Protein: 26-286
Range on HMM: 1-365/365
Sequence Identity: 23% (88 aa)

YNLLKTIGQGANCKVVLIQDSLNRKYYA----------------AKVFKLAKTYPNAKTSLPLEREVRIMKKIH----------------HENIVNFREV
|...| ||||.  .| . .. ...| .|                .|... |. . . .    ...| .||..|.                | ||... |.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

LFAPEKNAFYLIMEWGNCGSLQNLI---DTKI--------KIAEKTIASIFRQLVN---------------GLSYLHSQG-FVHQDIKPSNVLLFSDGTA
     .| .||.||  . |.|. .|   ..|         .. || |. |..|...               .| ||||..  .| ||||.|.|.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIGDFGIGH-----------------------------------SFQSAETVVGTPAYQAPEIFDDSYDDLTDLPALDPAKEDVWSLGVTLFETLFGKLP
|| |||.                                     ... . |..||| |.||||.    .|   .      | |.|||||.|.| ||||.|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FTGENVYEIARTIRKIGLVLP----------------NNISGPLSDLLFG----MLNPDPTKRLS-LDEVKESSFF
|      ..     || .  |                ...|    ||.      ||. || ||..  .....  .|
F------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 94222.m00135.AA Ciliate-E2-Unclassified 26-286 23 4.8e-52 178.81 In-house 1-352 (352) Show / Hide 
Range on Protein: 26-286
Range on HMM: 1-352/352
Sequence Identity: 23% (83 aa)

YNLLKTIGQGANCKVVLIQDSLNRKYY-----AAKVFKLA-KTYPNAKTSLPLEREVRIMKK---------------IHHENIVNFREVLFAPEKNAFYL
|...|.||||...|| . |.. .  .|     . |. . . | . | .  . .| .    ||               ..| ...  ...     |. .|.
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

IMEWGNCGSLQNLIDTKIK-----------------IAEKTIA-----SIFRQLVNGLSYLHSQG-FVHQDIKPSNVLLFSDG---TAKIGDFGIGH---
.||  . |.|.. |  . |                 . |. ..      .|.|...||.|||... ..| ||||.|.|. ..|     || ||||     
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

----------------SFQSAETVVGTPAYQ----APEIFDD-SYDDLTDLPALDPAKEDVWSLGVTLFETLFGKLPFTGENVYE---------------
                ..| . |..||| |.    |||...   ||. .        | |.||||| |.| |||..|| ..| ..               
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA------YKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRK

IARTIRKIG----LVLPN-----NISGPLSDLLF----GMLNPDPTKRLSLDEVKESSFF
. . . | .       |.     ..|    |..      ||. .| ||........  .|
QLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 94222.m00135.AA CAMKL 26-200 30 1e-51 163.26 In-house 1-213 (297) Show / Hide 
Range on Protein: 26-200
Range on HMM: 1-213/297
Sequence Identity: 30% (66 aa)

YNLLKTIGQGANCKVVLIQD-SLNRKYYAAKVFKLAKTY-PNAKTSLP----------LEREVRIMKKIH---HENIVNFREVLFAPEK----NAFYLIM
|...||.|.|.  || | .. ..... .| |. .  |.     ... .          ..||..|||...   |.||. . ||.  ||.    . .||.|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EWGNCGS--LQNLIDTK----IKIAEKTIASIFRQLVNGLSYLHSQGFVHQDIKPSNVLLFSDG--TAKIGDFGIG-----H---SFQSAETVVGTPAYQ
|    |.  |.. |. .     .. |.    .|||.| ...|.||.| || |||| |.|| ..|  ..|| ||| .     .   . |  .|  |.|.|.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEIFDD---SYD
||||| .   .||
APEIFQGNNKPYD
Kinase 94222.m00135.AA ULK 26-286 26 4.5e-51 175.99 In-house 1-324 (324) Show / Hide 
Range on Protein: 26-286
Range on HMM: 1-324/324
Sequence Identity: 26% (88 aa)

YNLLKTIGQGANC-KVVLIQDSLN---RKYYAAKVFKLAKTYPNAKT------SLPLEREVRIMKKIH---HEN--IVNFREVLFAPEKNAFYLIMEWGN
|.| . .|.|.   ||    .  .    .|.|.|.  . |   . .          |..|..||||..   |.|  || . ...  .  | .|.|||  |
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

CGSLQNLIDTKIK---------IAEKTIASIFRQLVNGLSYLHSQGFVHQDIKPSNVLLFSD------------GTAKIGDFGIGHSFQS-------AET
.| |...| .. |         . |. . ..|.|..||. .||... .| ||||.| |.  .            |..||.||| . ....         |
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

VV------GTPAYQAPEIFDDS-----YDDLTDLPALDPAKEDVWSLGVTLFETLFGKLP----FTGENVYEIART----------IRKIGLVLP-----
 |      ||| | ||.|. .      |.|         .| |.||||. ..| |.|| |    |. .. | |..           |..  .  |     
CVNEKRIKGTPLYMAPQILQGQGEQKPYYD---------YKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKD

NNISGPLSDLLFGMLNPDPTKRLSLDEVKESSFF
..||  . ||. .||  |...| | .|. .  .|
PKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 94222.m00135.AA ULK 26-286 26 6.1e-50 172.24 In-house 1-329 (329) Show / Hide 
Range on Protein: 26-286
Range on HMM: 1-329/329
Sequence Identity: 26% (88 aa)

YNLLKTIGQGANCKVVLIQDSLNR----KYYAAKVFKLAKTYPNAKT------SLPLEREVRIMKKIH--------HENIVNFREVLFAPEKNAFYLIME
|.| . .|.|.  ||    .  .     ...|.|.  . |   . .          |..|..||||..        |.||| . ...  .  | .|.|||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

WGNCGSLQNLIDTKIK----------IAEKTIASIFRQLVNGLSYLHSQGFVHQDIKPSNVLLFSD------------GTAKIGDFGIGHSFQS------
  | | |...| .. |          . |. . ..|.|..||. .||... .| ||||.|.|.  .            |..||.||| . ....      
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-AETVV------GTPAYQAPEIFDDS-----YDDLTDLPALDPAKEDVWSLGVTLFETLFGKLP----FTGENVYEIART----------IRKIGLVLP-
 . | |      ||| | ||.|. .      |.|         .| |.||||. ..| |.|| |    |. .. . | .           |.|. |  | 
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYD---------YKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPK

----NNISGPLSDLLFGMLNPDPTKRLSLDEVKESSFF
    ..||  . ||. .||  |...| | .|. .  .|
DGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 94222.m00135.AA STE 26-286 21 7.5e-48 165.29 In-house 1-359 (359) Show / Hide 
Range on Protein: 26-286
Range on HMM: 1-359/359
Sequence Identity: 21% (81 aa)

YNLLKTIGQGANCKVVLIQDSL---------------NRKYYAAKVFKLAKTYP-------------NAKTSLPLEREVRIMKKIH--HENIVNFREVLF
. ... ||.||  .|..  .                 . ...| |. .| .  .             | .    ...|..|||| .  |.|||..    |
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

-----APEKNAFYLIMEWGNCGSLQNLIDTKIKIA--------------EKTIASIFRQLVNG-LSYLHSQGFVHQDIKPSNVLLFSDGTAKIGDFGIGH
       ...  ...||. . |||  .|..| ..               |. || | ||.. | |.||||.. .| ||||.|.||     .|. |||.  
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

SFQS--------------------AETVVGTPAYQAPEIFD-------DSYDDLTDLPALDPAKEDVWSLGVTLFETLFGKLPF-TGENVYEIARTIRKI
....                      |.|||| . |||. .       . ||          .| |.|||| |. | . || |. .. . . . ......
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYD----------TKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNY

GLV---------------LPN-------------------NISGPLSDLLFGMLNPDPTKRLSLDEVKE--SSFF
. .               ||.                   . | .. | .   |. || || . ..  .   .|.
HMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 94222.m00135.AA RSK 29-286 30 4.7e-46 159.33 In-house 1-278 (278) Show / Hide 
Range on Protein: 29-286
Range on HMM: 1-278/278
Sequence Identity: 30% (87 aa)

LKTIGQGANCKVVLIQDS---LNRKYYAAKVFKLAKTYPNAKTSLPLEREVRIMKKIH-HENIVNFREVLFAPEKNAFYLIMEWGNCGSLQNLIDTKIK-
||  |||.. || | .      ....|| || | ||  ...|.     .|..|.. .  | .||.  ..   ..|  .|||||  . | |   . ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGK--LYLIMEYCRGGELFTHLQKEKHF

--IAEKTIASIFRQLVNGLSYLHSQGFVHQDIKPSNVLLFS---DGTAKIGDFGIGHSF-----QSAETVVGTPAYQAPEIFD----DS-YDDLTDLPAL
  . |.. . .....|  ...||.||..| |.||.|.|. .   .|. |. |||    |     | . | ..| .| |||.      .. .|        
GCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKAC-----

DPAKEDVWSLGVTLFETLFGKLPFTG---ENVYEIARTIRKIG--LVLP--NNISGPLSDLLFGMLNPDPTKRLS-----LDEVKESSFF
     |.||||| ..| |.|..||.|   .|  || . |.|    | .|  ...| .  ||. .||  || |||.     ..|.|....|
-----DWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 94222.m00135.AA CAMKL 214-286 23 1.1e-20 62.63 In-house 218-297 (297) Show / Hide 
Range on Protein: 214-286
Range on HMM: 218-297/297
Sequence Identity: 23% (19 aa)

DVWSLGVTLFETLFGKLPFTGENV--------YEIARTIRKIGLV-LPNNISGPLSDLLFGMLNPDPTKRLSLDEVKESSFF
|.||.||.|.  ..|.||| ....        |.  ....  .    .. .| .. ||. .||...|.|| .......  ..
DIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 94222.m00135.AA Pkinase_Tyr 72-172 29 1e-14 50.43 Pfam 50-156 (270) Show / Hide 
Range on Protein: 72-172
Range on HMM: 50-156/270
Sequence Identity: 29% (32 aa)

LEREVRIMKKI-HHENIVNFREVLFAPEKN-AFYLIMEWGNCGSLQNLIDT----KIKIAEKTIASIFRQLVNGLSYLHSQGFVHQDIKPSNVLLFSDGT
. ||..|||.. ||.|||..  |    ..    |..||   .|.| .   .    | ..  |.. .. .|  .|..||.|....| |.   |.|. ....
FMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNV

AKIGDFG
.||.|||
VKICDFG
Kinase 94222.m00135.AA TyrKc 26-286 21 5e-14 4.11 SMART 1-280 (280) Show / Hide 
Range on Protein: 26-286
Range on HMM: 1-280/280
Sequence Identity: 21% (66 aa)

YNLLKTIGQGANCKVVLIQDSLNRKYYAAKVF-KLAKTYPNAKTSLPLEREVRIMKKI--HHENIVNFREVLFAPEK-----NAFYLIMEWGNCGSLQNL
  |.|..| || ..|.. . .        .|  |  | .        . || |||.|.  ||.|||..  |   ..         ...||    |.|.. 
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

I-DTKIKIAEKTIASIFRQLVNGLSYLHSQGFVHQDIKPSNVLLFSDGTAKIGDFGIGHSFQSA-------ETVV-----GTP-----AYQAPEIFDDS-
. ... |.  |.  |.  |  .| .||||....| |.   |.|. ...|.||.|||      .        .. .     |.         ||| .... 
LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YDDLTDLPALDPAKEDVWSLGVTLFETL-FGKLPFTG-----ENVYEIARTIRKI-GLVLPNN--------ISGPLSDLLFGMLNPDPTKRLSLDEVKES
.   .          |||| ||...| . .|. |  |      . .|. . ...   .  | |         .  . ..     . || .| .  |.   
FTTKS----------DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--H

SFF
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ECF
Kinase 94222.m00135.AA Pkinase_Tyr 214-246 33 0.041336 7.77 Pfam 196-231 (270) Show / Hide 
Range on Protein: 214-246
Range on HMM: 196-231/270
Sequence Identity: 33% (12 aa)

DVWSLGVTLFETLF-GKLP-FTGENVYEIARTI-RK
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DVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYED
Kinase 94222.m00135.AA Pkinase_Tyr 26-42 29 5.951454 0.46 Pfam 1-17 (270) Show / Hide 
Range on Protein: 26-42
Range on HMM: 1-17/270
Sequence Identity: 29% (5 aa)

YNLLKTIGQGANCKVVL
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ITFGKKLGEGAFGEVYK