Gene 84085.m00089 (T.vaginalis)

84085.m00089

Species: T.vaginalis
Alias: 84085.m00089, TvagK0032
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
84085.m00089.AA Protein None 325 None Fasta, JSON
84085.m00089.kin_dom Protein Kinase Domain None 279 None Fasta, JSON

Protein domain

Protein domains of 84085.m00089.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 84085.m00089.AA MARK 8-253 32 2.7e-79 258.85 In-house 1-256 (262) Show / Hide 
Range on Protein: 8-253
Range on HMM: 1-256/262
Sequence Identity: 32% (83 aa)

YQIFGEIGRGSSGSVHTAKNTQNNQELCVKIIEKSSMNTKEDIEFFRREVSILSALQHKNIAEYHDLLE--DSNN-YYLFQELCQGENLTKYLENN--RP
| .  .|| || . |  | ..  ... ..||.|| ..|  . .. ..||..|.. |.|.|| ....  |  ....  ||  |.. | .|  |...   ..
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

ISERQIEIIFHQFCSALSYIHKAGVGHRDLKPDNIIIGANN--IVKIIDFGLSTDD-NQHLRTTFCGSLAYAAPECIRREPYIAWRSDMWSLGVILFQMN
..|.    ||.| .||..| |. .. |||.||.|| | .|.   .||||||.|.   .  . .||||...|.||| . ..|| .   |.|||||.|. | 
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

TGRLPWK--TSNIVQLMKQITSGNFEIPPSIPAPIKNIIVQCLNQDPTLRPSADDL
.|..|..  | ....|.|.|..|...||. ... ..|.| . |. .|  ||.....
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEI
Kinase 84085.m00089.AA CAMKL 8-253 28 1e-78 250.84 In-house 1-291 (297) Show / Hide 
Range on Protein: 8-253
Range on HMM: 1-291/297
Sequence Identity: 28% (84 aa)

YQIFGEIGRGSSGSVHTAKNTQN-NQELCVKIIEKSSMNTKEDIEFF------------RREVSILSALQ---HKNIAEYHDLLEDSNN------YYLFQ
|.|  ..|.|| | |  |..... ...  .|||.|. .. .. ..              |||..|.. |.   |.||   .. .|....      .||. 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELCQGEN--LTKYLENN----RPISERQIEIIFHQFCSALSYIHKAGVGHRDLKPDNIIIGANN--IVKIIDFGLSTD-DN-----QHLRTTFCGSLAYA
|.|.| .  |  |....    ....|..   .| | .||..|.|. |. |||.||.|| .  |.   .||||||.|.  ..      .. .|||||..|.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APECIRR--EPYIAWRSDMWSLGVILFQMNTGRLPWKTS--------NIVQLMKQITSGNFEIP--PSIPAPIKNIIVQCLNQDPTLRPSADDL
||| . .  .||..   |.||.||||. | .|.||..          ||  |...| .| ...|  .... . ...| . |. .|. ||.....
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQI
S_TKc 84085.m00089.AA S_TKc 8-259 29 1.6e-78 268.07 SMART 1-231 (231) Show / Hide 
Range on Protein: 8-259
Range on HMM: 1-231/231
Sequence Identity: 29% (79 aa)

YQIFGEIGRGSSGSVHTAKNTQNNQELCVKIIEKSSMNTKEDIEFFRREVSILSALQHKNIAEYHDLLEDSNNYYLFQELCQG--ENLTKYLENNRP---
|.|  .||.|. |.|. ....  ...  .|||           | .|||..||.  .|.||  ..|  .| ...|.. |.| |   .| .|......   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---ISERQIEIIFHQFCSALSYIHKAGVGHRDLKPDNIIIGANNIVKIIDFGLSTDDNQHLRTTFCGSLAYAAPECIRREPYIAWRSDMWSLGVILFQMN
   ..| ..  ...| |.|| |.|. |. ||||||.|| .     .||.||||..       |||||.. | ||| .   .|   ..|.||.|.||. | 
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

TGRLPWKTSNIVQLMKQITSGNFEIPPSIPAPIKNIIVQCLNQDPTLRPSADDLIG-------VRFT
.|. |.   .. ...|.|           . . |..| .||. ||. ||.| ..           . 
CGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 84085.m00089.AA CAMK 13-252 20 9.3e-78 249.97 In-house 1-418 (425) Show / Hide 
Range on Protein: 13-252
Range on HMM: 1-418/425
Sequence Identity: 20% (87 aa)

EIGRGSSGSVHTAKNTQNN------------QELCVKIIEKSSMN-------------------------TKEDIEFFRREVSILSALQ-------HKNI
..|||| | |. .......            |.  .|||.|. .                          . .| ...|||..|.. ||       |.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

AEYHDLLEDSNN-------------------YYLFQ---ELCQGE----NLTKYLENN---------------RPISERQIEIIFHQFCSALSYIHKAGV
   ..  ||...                   .|..    |.|.|      |  |.  .               . ..||.   .|.| |||. |.|. ..
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

GHRDLKPDNIIIGAN-----------------NIVKIIDFGLSTDDNQ-------------------------HLRTTFCGSLAYAA-PECIRR------
 ||||||.|| .  |                 | .||||||...  ..                         .. .||||...|.| || ...      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------EPYIAWRSDMWSLGVILFQMNTGRLPWKTS-------------NIVQLMKQITSGNFE-IPPSIPA-----------------------PIKN
       .||.   .||||.||||. | .|..|.  .             |. .|...|..|... .|| ..                          |.
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

IIVQCLNQDPTLRPSADD
 | ..|. ||. |.....
LIRKMLQVDPEKRMTIEQ
Kinase 84085.m00089.AA Pkinase 8-253 30 1.7e-74 258.62 Pfam 1-287 (293) Show / Hide 
Range on Protein: 8-253
Range on HMM: 1-287/293
Sequence Identity: 30% (88 aa)

YQIFGEIGRGSSGSVHTAKNTQNNQELCVKIIEKSSMNTKEDIEFFR-REVSILSALQHKNIAEYHDLLEDSNNYYLFQELCQGE----NLTKYLE--NN
|.| . ||.||.|.|  ...  .... .||||.|.. . ..|.. .| .|..|.  |.|.|| ...|  ||....|. .|.|.|      |  |..  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RPI--SERQIEIIFHQFCSALSYIHKAGVGHRDLKPDNIIIGANNIV----KIIDFGLST---DDNQHLRTTFCGSLAYAAPECIRREPYIAWRSDMWSL
...  ||...  .. | ...| |.|. |. ||||||.|| |  |. .    ||.||||.      |..  |||||.. |.||| ||  .|.  ..||||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVILFQMNTGRLPWKTS------NIVQLMKQITSGNFEIPPSIP---------------------APIKNIIVQCLNQDPTLRPSADDL
|.||..| .||.|.. .      .  |....| .. .. . . .                      . | .|  ||..||. ||.|...
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI
Kinase 84085.m00089.AA AMPK 8-259 32 6e-68 200.83 In-house 1-254 (254) Show / Hide 
Range on Protein: 8-259
Range on HMM: 1-254/254
Sequence Identity: 32% (82 aa)

YQIFGEIGRGSSGSVHTAKNTQNNQELCVKIIEKSSMNTKEDIEFFRREVSILSALQHKNIAEYHDLL-EDSNNYYLFQELCQGENLTKYLENNRPISER
|.|   ||.|..| |  .. .. ...  .||..|  .  ... |  .||..||  . | .|    . . |     ... |  .|  |  |   .. ..||
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

QIEIIFHQFCSALSYIHKAGVGHRDLKPDNIIIGANNIVKIIDFGLS--TDDNQHLRTTFCGSLAYAAPECIRREPYIAWRSDMWSLGVILFQMNTGRLP
.    | |  |...|.|. .. |||||| |. . .|. .|| |||||    |.. |.|  |||  ||||| |   .|     | || ||||. |  |.||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTA-CGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLP

WKTSNIVQLMKQITSGNFEIPPSIPAPIKNIIVQCLNQDPTLRPSADDLIGVRFT
   .|. .| | |..| ..||  .   .|..| . |. ||. | . .|.    . 
FDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 84085.m00089.AA ULK 8-247 25 1.3e-65 224.24 In-house 1-317 (329) Show / Hide 
Range on Protein: 8-247
Range on HMM: 1-317/329
Sequence Identity: 25% (81 aa)

YQIFGEIGRGSSGSVHTAKNTQN----NQELCVKIIEKSSMNTKED-------IEFFRREVSILSAL----QHKN----IAEYHDLLEDS--NNYYLFQE
|..  ..| || | |. ..| ..    |.   .|.|.|..|| |..       ......|. |.  |    .|||    | ...| .|.|  ||.|...|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LCQGENLTKYLENNRP----------ISERQIEIIFHQFCSALSYIHKAGVGHRDLKPDNIIIGANN------------IVKIIDFGLSTD---D--NQH
.|.| .| .|...|..          .|| .. ..|.|..... ..|| .. |||.||.|| |  ..            ..|| |||..     |  .| 
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

LRTTFC------GSLAYAAPECIR----REPYIAWRSDMWSLGVILFQMNTGRLP---WKTSNIV-----QLMKQ-------ITSGNFEIP-----PSIP
. .|.       |.  | ||. .     ..||    .|.||||.|...| .|. |   |  .  .     .| ..       | . ....|     | | 
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

APIKNIIVQCLNQDPTLR
  .|..| ..|  |.. |
PECKDLIRRMLQYDEKDR
Kinase 84085.m00089.AA Ciliate-E2 8-254 22 1.6e-65 223.89 In-house 1-360 (365) Show / Hide 
Range on Protein: 8-254
Range on HMM: 1-360/365
Sequence Identity: 22% (83 aa)

YQIFGEIGRGSSGSVHTAKNTQN-----------------------NQELCVKIIEKSSMNTKEDIEFFRREVS----------ILSALQHKNIAEYHDL
| .   ||.|. |||  .|. ..                       ...  .||..|.  . .. ..   ||.           ||. |.|.|| .... 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

LE--DSNNYYLFQELCQGENLTKYLENNR-----------PISERQIEIIFHQFCS---------------ALSYIHKAG-VGHRDLKPDNIIIGANNIV
 .  | ||.||  |.||| .| .|..||.           ...|..|  |. | ..               || |.|. . . |||.||.||..     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIIDFGLSTDDNQ---------------------------------HLRTTFCGSLAYAAPECIRREPY--------IAWRSDMWSLGVILFQMNTGRLP
||||||||.. ..                                 ..  |.||.. | ||| .....|            .|.|||||||..| .|..|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

WKTSNIVQLMKQITSGNFEIP------------------PSIPAPIKNIIVQ----CLNQDPTLRPS-ADDLI
.        ..||  .....|                   ...   |..| .    .|. ||  |.. .....
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQIL
Kinase 84085.m00089.AA ULK 8-245 26 1.7e-65 223.92 In-house 1-310 (324) Show / Hide 
Range on Protein: 8-245
Range on HMM: 1-310/324
Sequence Identity: 26% (82 aa)

YQIFGEIGRGSSG-SVHTAKNTQN---NQELCVKIIEKSSMNTKED-------IEFFRREVSILSALQ---HKN--IAEYHDLLEDS--NNYYLFQELCQ
|..  ..| || |  |. ..| ..   ||   .|.|.|..|| |.        ......|..|.  |    |.|  | ...| .|.|  ||.|...|.|.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GENLTKYLENNRP---------ISERQIEIIFHQFCSALSYIHKAGVGHRDLKPDNIIIGANN------------IVKIIDFGLSTD-DN----QHLRTT
| .| .|...|..         .|| .. ..|.|.|... ..|| .. |||.||.|| |  ..            ..|| |||..   ||    | ...|
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

FC------GSLAYAAPECIR----REPYIAWRSDMWSLGVILFQMNTGRLP---WKTSNIV----QLMKQ-------ITSGNFEIP-----PSIPAPIKN
..      |.  | ||. .     ..||    .|.||||.|...| .|. |   |  .. .    .| ..       |   ....|     | |   .|.
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

IIVQCLNQDPT
.| ..|  |..
LIRRMLQYDEK
Kinase 84085.m00089.AA STE 8-259 20 8.9e-62 211.55 In-house 1-359 (359) Show / Hide 
Range on Protein: 8-259
Range on HMM: 1-359/359
Sequence Identity: 20% (73 aa)

YQIFGEIGRGSSGSVHTAKNT------QNNQE---------LCVKIIEKSSMNT--------------KEDIEFFRREVSILSALQ--HKNIAEYHDLLE
... ..||.|..|.|..|.|       .....           .|...... |.              .|... . .|..|.. ..  |.|| .|..  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DS-------NNYYLFQELCQGENLTKYLENN--------------RPISERQIEIIFHQFCSA-LSYIHKAGVGHRDLKPDNIIIGANNIVKIIDFGLST
.        .. ... |.. |  |.. ....               ...| || .| .| . . |.|.|. .. |||.||.|| .     ||..|||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

DDNQH------------------LRTTFCGSLAYAAPECIRR-----EPYIAWRSDMWSLGVILFQMNTGRLPWKTSNIVQLMKQIT--SGNFE------
  ...                   |.||.|.  . ||| |..     ..    ..|.||||  .  | ||. || . .  . | .|.  .. ..      
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----IPPSIP-----------------------APIKNIIVQCLNQDPTLRPSADDLIG--VRFT
     ||..|                        . |. | .||. ||  ||.|..|.     | 
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 84085.m00089.AA Ciliate-E2-Unclassified 8-254 22 8.9e-55 188.29 In-house 1-347 (352) Show / Hide 
Range on Protein: 8-254
Range on HMM: 1-347/352
Sequence Identity: 22% (77 aa)

YQIFGEIGRGSSGSVHTAKNTQNNQELCVKIIEKSSMNTKEDIEF-----------FRRE---VS--------ILSALQHKNIAEYHDLLEDSNNYYLFQ
| |   ||.|. |.|. ... ...|    |.. |. .. .  |..           ....   ..        ||. ..| .|  ...  .| .| |.  
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

ELCQGENLTKYLENN-----------------RPISERQIE-----IIFHQFCSALSYIHKAG-VGHRDLKPDNIIIGANN---IVKIIDFGLST-----
|.|.| .| .|....                 . ..|.|.       .| | ...|.|.|. . . |||.||.||..  |.    .||||||.|      
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

----DDN--------QHLRTTFCGSLAYA----APECIRREPYIA---WRSDMWSLGVILFQMNTGRLPWKTSNIVQ----------------LMKQITS
    ...        |.. .||||.. |     |||..... |       .|.|||||||..| .|..| .  |  |                | ..|  
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

GNFEIPP--------SIPAPIKNIIV----QCLNQDPTLRPSADDLI
.|...|.         ..   |..|     ..|. .|  |.......
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQIL
Kinase 84085.m00089.AA MELK 8-259 31 5.5e-51 172.35 In-house 1-254 (254) Show / Hide 
Range on Protein: 8-259
Range on HMM: 1-254/254
Sequence Identity: 31% (80 aa)

YQIFGEIGRGSSGSVHTAKNTQNNQELCVKIIEKSSMNTKEDIEFFRREVSILSALQHKNIAEYHDLLEDSNNYYLFQELCQGENLTKYLENNRPISERQ
|... ||| |  . |. |     || . .||..|  .   .|.   . |.  | .|.|..| . . ..|  . ...  | | | ..  |.  .  ..| .
YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQLG--HDLPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEE

IEIIFHQFCSALSYIHKAGVGHRDLKPDNIIIGANNIVKIIDFGLST----DDNQHLRTTFCGSLAYAAPECIRREPYIAWRSDMWSLGVILFQMNTGRL
   .| |  ||..|.|  |  ||||||.|...  .  .|.|||||        ..|   | |||.|||||| |.   ||    |.||.|..|. .  | |
TRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFL

PWKTSNIVQLMKQITSGNFEIPPSIPAPIKNIIVQCLNQDPTLRPSADDLIGVRFT
|.   |.  . |.| || .| |. .    |... . |  ||. | |  .|.   . 
PFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase 84085.m00089.AA TyrKc 8-258 23 1.8e-15 27.47 SMART 1-280 (280) Show / Hide 
Range on Protein: 8-258
Range on HMM: 1-280/280
Sequence Identity: 23% (68 aa)

YQIFGEIGRGSSGSVHTAKNTQNNQELCVKIIEKSSMNTKEDIEFFRREVSILSAL--QHKNI-AEYHDLLEDS------NNYYLFQELCQGENLTKYLE
 .   ..|.|  | |. .. .   ..  || . ...      .| |.|| .|.. |  .|.|| . |   ....        ...  |.. . .| .|| 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

NNRP-ISERQIEIIFHQFCSALSYIHKAGVGHRDLKPDNIIIGANNIVKIIDFGLS---TDD------NQHLRTTF--CGS----LAYAAPECI-RREPY
..|| .. ..   . .| ..  .|.|. .. ||||   |. .|.|..||| |||||   .||       .  |..   .|     .   |||||  ..  
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

IAWRSDMWSLGVILF-QMNTGRLPWKT-----SNIVQLMKQITSGNFEIPPSI---------PAPIKNIIVQCLNQDPTLRPSADDLIGVRF
..  || || || ..  .  |  |.        .  ...... .|.   .|           |. . .|. || . ||  ||.  ..   .|
TK--SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase 84085.m00089.AA Pkinase_Tyr 13-155 24 5.9e-09 30.95 Pfam 6-160 (270) Show / Hide 
Range on Protein: 13-155
Range on HMM: 6-160/270
Sequence Identity: 24% (38 aa)

EIGRGSSGSVHTAKNT----QNNQELCVKIIEKSSMNTKE--DIEFFRREVSILSAL-QHKNIAEYHDLLE-DSNN--YYLFQELCQGENLTKYLEN---
..|.|. |.|. .. .    .....  ||.. | .   ..    .|.| |..|.. | .|.||  ..     ..    .|.  |.... .| .|| .   
KLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHRE

-NRPISERQIEIIFHQFCSALSYIHKAGVGHRDLKPDNIIIGANNIVKIIDFGLSTD
 ..|..  ..  . .| .....| .  .  ||||   |. .. ||.||| ||||. |
DKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARD
Kinase 84085.m00089.AA Pkinase_Tyr 186-254 27 0.18699 5.55 Pfam 195-267 (270) Show / Hide 
Range on Protein: 186-254
Range on HMM: 195-267/270
Sequence Identity: 27% (20 aa)

SDMWSLGVILFQMNT-GRLP-WKTSNIVQLMKQI-TSGN-FEIPPSIPAPIKNIIVQCLNQDPTLRPSADDLI
|| || || .. . | |. | ..     .....|  .|.  ..|.  |..| ... || ..||  ||.  ...
SDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIH