Gene 82488.m00083 (T.vaginalis)

82488.m00083

Species: T.vaginalis
Alias: 82488.m00083, TvagK0948
External Links:
Annotation:

Classification

Group: CMGC
Family: SRPK

Sequence

Name Sequence Type Origin Length Description Download
82488.m00083.AA Protein None 406 None Fasta, JSON
82488.m00083.kin_dom Protein Kinase Domain None 338 None Fasta, JSON

Protein domain

Protein domains of 82488.m00083.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 82488.m00083.AA CMGC 66-403 16 7.4e-58 188.28 In-house 1-513 (513) Show / Hide 
Range on Protein: 66-403
Range on HMM: 1-513/513
Sequence Identity: 16% (88 aa)

YQIKTMIGRGTFCLVWLAYDYLRCEN--------------VAIKVLK-RLYDDNQDD-----------SQFEDELLMNLYLSGLDDT----------SKQ
|.|   ||.||.  |. ..| .. ..              |||| .| .  ...|             .. | ..|..|   .               . 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDP-NWQRRDDPDNKHHN

-ITHFYDVFYYED-----------------HCCFVLELVSQNILTFINYFDDIYVP------------------------IPLKLIKKIVADTLKGLN--
 | . ||.||...                 | ..| |.. .. . .|    . | .                        ... .|. .    |.||.  
NIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLK

FMHKNE--TIHTDLKPENVFAE------------RPIFPYEPFSEDDTREVFNCLEDDESTINFKLGDFGNSCFADN-----------------------
..|..    ||.||||||.               .            .. . | .    .  . |..|||.... ..                       
YCHSHWGNIIHRDLKPENILINHNCELITRMMWKS------------ED-W-NPC---QKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPN

-ILNDLIQTRQYRSPEVLLGLP----------YTSSADIWSLACMTFELATR--------HHLFD-----PVLSDSDKEETPKNRDLFD-------AVHL
  . . ..|| ||.||.||| .          ||.. |.||..|. .|. |.        . ||      |.                |         .|
RPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPN----------------DDKNGKSHIDQL

SMIESVLGQI----------------PRDWARNGKLY------------------PSLYNRHGELIATYHKQLPCLYNLLIKHGLN--------------
 .|  ||| .                ...|    ||.                  .. . .. .   .. .. |   . |..   |              
FKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWI

----------------EQDAAELTEFLEPMLAIIPKQRPTAEQLLDSPWL
                ...  .. ..|. || . |..|.|||| |. |..
YEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase 82488.m00083.AA SRPK 233-403 40 8.9e-53 133.17 In-house 392-554 (554) Show / Hide 
Range on Protein: 233-403
Range on HMM: 392-554/554
Sequence Identity: 40% (70 aa)

INFKLGDFGNSCFADNILNDLIQTRQYRSPEVLLGLPYTSSADIWSLACMTFELATRHHLFDPVLSDSDKEETPKNRDLFDAVHLSMIESVLGQIPRDWA
|  |. |.|| |. .    . |||||||||||..| .|  .|||||.||| |||||  .||.|      .|.. .. |     |.  |.  .| ||.  |
IKIKIADLGNACWVHHHFTEDIQTRQYRSPEVIIGAGYNTPADIWSTACMAFELATGDYLFEP----HSGEDYSRDDD-----HIAHIIELCGKIPWHFA

RNGKLYPSLYNRHGEL--IATYHKQLPCLYNLLI-KHGLNEQDAAELTEFLEPMLAIIPKQRPTAEQLLDSPWL
..||      |. |||  | . . ..| |.| || | .. ...|.. ..|| |||  .|  | ||...| .|||
LSGKYSREFFNKKGELRHIPKLK-PWP-LMNVLIEKYEWSHEEAKQFEDFLMPMLHYNPEKRATAKECLQHPWL
Kinase 82488.m00083.AA S_TKc 66-403 17 1.7e-49 171.63 SMART 1-231 (231) Show / Hide 
Range on Protein: 66-403
Range on HMM: 1-231/231
Sequence Identity: 17% (63 aa)

YQIKTMIGRGTFCLVWLAYDYLRCENVAIKVLKRLYDDNQDDSQFEDELLMNLYLSGLDDTSKQITHFYDVFYYEDHCCFVLELVSQ---NILTFINYFD
|.|   ||.|.|  |.....    . ||||..|          ... |. .           . | ..||||.  || ..|.|....   . ...|    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG

DIY--VPIPLKLIKKIVADTLKGLNFMHKNETIHTDLKPENVFAERPIFPYEPFSEDDTREVFNCLEDDESTINFKLGDFGNSCFADNILNDLIQTRQYR
     .|.|   ...... ....|...|..  || ||||||..  .                           . |..||| ...     . .. |. |.
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---------------------------HIKICDFGLARQL----TTFCGTPWYM

SPEVLLGLPYTS-SADIWSLACMTFELATRHHLFDPVLSDSDKEETPKNRDLFDAVHLSMIESVLGQIPRDWARNGKLYPSLYNRHGELIATYHKQLPCL
.||||   .|.  ..|.||. |. .|....  .|.               ...   .. .                                        
APEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP---------------QMQMMFKKIG----------------------------------------

YNLLIKHGLNEQDAAELTEFLEPMLAIIPKQRPTAEQLLD-------SPWL
               |. .|.. .|   |..|||| ..|         ||.
-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 82488.m00083.AA Pkinase 66-294 22 6e-36 128.19 Pfam 1-213 (293) Show / Hide 
Range on Protein: 66-294
Range on HMM: 1-213/293
Sequence Identity: 22% (55 aa)

YQIKTMIGRGTFCLVWLAYDYLRCENVAIKVLKRLYDDNQDDSQFED--ELLMNLYLSGLDDTSKQITHFYDVFYYEDHCCFVLELVSQNILTFINYFDD
|.|.  ||.|.|  |.....   .. ||.|..|.  .. . | .     |. . . |.     .. |  .||.|...||...|.|..       .  || 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-----HPNIVRLYDWFEDKDHIYMVMEYCEGGLY-VMDLFDY

IY----VPI--PLKLIKKIVADTLKGLNFMHKNETIHTDLKPENVFAERPIFPYEPFSEDDTREVFNCLEDDESTINFKLGDFGNSCF---ADNILNDLI
|      ..  . . .|...  .|.||...|..  || ||||||..  .   . .                      .|..||| ...    .  .... 
ISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA---------------------CVKICDFGLAKQFDYNNS-MTTFC

QTRQYRSPEVLL-GLPYTSSADIWSLACMTFELATRHHLFD
 |. |..|||.. | .|....|.||. |. .|..... .|.
GTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFP
Kinase 82488.m00083.AA Ciliate-E2 66-403 13 7.1e-30 99.72 In-house 1-365 (365) Show / Hide 
Range on Protein: 66-403
Range on HMM: 1-365/365
Sequence Identity: 13% (62 aa)

YQIKTMIGRGTFCLVWLAYDYLRCENVAIKVLKRLYDDNQD-----DSQFEDELLMN-----LYLSGLDDTSK---------Q------------ITHFY
| .  .||.|.|  |... ...  ...|||. .  .   .      . ... .. ..      ...  ..  .         .            |  .|
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQ-QRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMY

DVFY--YEDHCCFVLELVSQ-NILTFINYFDDIY-------VPIPLKLIKKIVADTLK---------------GLNFMHKNE-TIHTDLKPENVFAERPI
..|.   .... .|.|.... . . .|. ..           .. .| ||.| .  |.               .|...|..   || |.||||..     
ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

FPYEPFSEDDTREVFNCLEDDESTINFKLGDFGNSCFAD----------------------------------NILNDLIQTRQYRSPEVLLGLP-----
                           |. |||.| ..|                                  |. | .. |  | .||.| | .     
--------------------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQ

----YTSSADIWSLACMTFELATRHHLFDPVLSDSDKEETPKNRDLFDAVHLSMIESVLGQIPRDWARNGKLYPSLYNRHGELIATYHKQLPCLYNLLIK
    |. ..||||| .. .|. .  . |                                                                    . ..
KQKGYDYKCDIWSLGVILYEMLFGKPPF--------------------------------------------------------------------QQQI

HG----------------------LNEQDAAELTEFLEP----MLAIIPKQRPT-AEQLLDSPWL
.                        ...   |   ..      ||   |..|.| .||.|. ||.
KQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 82488.m00083.AA CLK 66-286 24 1.5e-29 85.23 In-house 1-240 (350) Show / Hide 
Range on Protein: 66-286
Range on HMM: 1-240/350
Sequence Identity: 24% (60 aa)

YQIKTMIGRGTFCLVWLAYDYLRCENVAIKVLKRLYDDNQDDSQFEDE-LLMNLYLSGLDDTSKQ--ITHFYDVFYY-EDHCCFVLELVSQNILTFINYF
| |.   | |||  |    |  .  . . .  .|  .   .... | .  . ..   .  .  ..  . . .| | |  .| | | ||   .|  |.   
YEIVCTLGEGTFGKVVECWDHKNGKKYVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFDYGHGHICIVFELYGLSIYDFMKSN

D----DIYVPIPLKLIKKIVADTLKGLNFMHKNETIHTDLKPENV-FAER------PIFPYEPFSEDDTREVFNCLEDDEST--INFKLGDFGNSC---F
       | | |.  |... .  .. ..|.|... .||||||||  |.        . |.|..    ...   ||  .  .    . .. |||.     |
NSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHDMKLTHTDLKPENICFVDSRFTHFDCTFKYNHKKKINKKS-NNCVCHYWHVKNTHICVIDFGSATKIRF

ADNILNDLIQTRQYRSPEVLLGLPYTSSADIWSLACMTFEL
 .    ....||.|| ||| |||..    |.|| .|  |||
DHEHHSTIVSTRHYRAPEVILGLGWSQPCDVWSIGCILFEL
Kinase 82488.m00083.AA STE 66-291 17 2.7e-26 89.93 In-house 1-266 (359) Show / Hide 
Range on Protein: 66-291
Range on HMM: 1-266/359
Sequence Identity: 17% (51 aa)

YQIKTMIGRGTFCLVWLAYDYLRC---EN------------VAIKVLKRLYDD-----------NQDDSQFEDELLMNL-YLSGLDDTSKQITHFYDVFY
...  .||.|.|  | .|..   |   ..            .|||...   ..           ...... ....|. .  .. ...... | ..|. ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

YE-------DHCCFVLELVS-QNILTFIN-YF---DDIY------VPIPLKLIKKIVADTLKG-LNFMHKNETIHTDLKPENVFAERPIFPYEPFSEDDT
.|       |... ..|...   .  .|. ..   ..         ..| ..|..|. ..||| |.. |..  || |.|| |..                
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL---------------

REVFNCLEDDESTINFKLGDFGNSCFADN-------------------ILNDLIQTRQYRSPEVLLG------LPYTSSADIWSLACMTFELATRHH
                || ||| .   ..                     | .. |  . .|||...       .|. ..||||| |.  |.|| ..
---------------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKP
Kinase 82488.m00083.AA DYRK2 66-202 32 9.1e-21 63.96 In-house 1-133 (318) Show / Hide 
Range on Protein: 66-202
Range on HMM: 1-133/318
Sequence Identity: 32% (46 aa)

YQIKTMIGRGTFCLVWLAYDYLRCENVAIKVL---KRLYDDNQDDSQFEDELLMNLYLSGLD-DTSKQITHFYDVFYYEDHCCFVLELVSQNILTFINYF
| |. .||.| |. |  .||. . . ||||..   ||.       .|   |. .  ...  | | .  . |  | ||.  | | ..|| | |.  .|   
YEILEVIGKGSFGQVVKCYDHKTKQHVAIKMIRNKKRFH------NQAYEEIRILHHIRRQDKDNTMNCVHMLDYFYFRNHHCITFELLSMNLYEYIK--

DDIYVPIPLKLIKKIVADTLKGLNFMHKNETIHTDLKPENV
   .  . |.|. .  .  |..|.| |||  || ||||||.
KNHFQGFSLQLVRRFAHSILQCLRFLHKNNIIHCDLKPENI
Kinase 82488.m00083.AA DYRK 66-202 35 2.6e-20 72.8 In-house 1-135 (320) Show / Hide 
Range on Protein: 66-202
Range on HMM: 1-135/320
Sequence Identity: 35% (51 aa)

YQIKTMIGRGTFCLVWLAYDYLRCENVAIKVLKRL--YDDNQDDSQFEDELLMNLYLSGL-DDTSKQITHFYDVFYYEDHCCFVLELVSQNILTFI--NY
|.|  .||.|.|. |  ..|  . | ||||....   .   .. .| | ..|.  ||.   .| .. . |.|| ||.  | | | || |.|   |.  | 
YEILEYIGKGSFGQVVKCWDHKTNEMVAIKIIRNNKRF---HRQAQIEIKILE--YLNQQDPDDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNH

FDDIYVPIPLKLIKKIVADTLKGLNFMHKN-ETIHTDLKPENV
|.     ..|.|..|.    |..| |.||| . || ||||||.
FQGF---FSLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENI
Kinase 82488.m00083.AA CAMK 71-284 14 6.6e-19 56.89 In-house 1-325 (425) Show / Hide 
Range on Protein: 71-284
Range on HMM: 1-325/425
Sequence Identity: 14% (51 aa)

MIGRGTFCLVWLAYDY-LRC-----------ENVAIKVLKR-LYDDNQ-------------------------DDSQFEDELLMNLYLSGLDD--TSKQI
 .|||.|. | |...    .           . ||||....   .|.|                         |  ... |. .   |.|..     . |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

THFYDVFYY-------------------EDHCCFVL---ELVSQN-----ILTFINYFDDIY-----------VPIPLKLIKKIVADTLKGLNFMHKNET
 ..|.|.                     ..|...|.   |..|       .. .|    . .             .. .  ....   . .....|..  
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHTDLKPENVFAERP-----------IFPYEPFSEDDTREVFNCLEDDESTINFKLGDFGNSCFADN--------------------------ILNDLIQ
.| ||||||.                ||.                   ... | |. ||| ... |                            ...   
VHRDLKPENILLDDNNDDSDPVEHDEIFD-------------------WNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCG

TRQYRS-PEVLLG--------------LPYTSSADIWSLACMTF
|  | . ||||.|               .|. ..|.||. ....
TPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILY
Kinase 82488.m00083.AA HIPK 66-202 31 1.1e-18 54.95 In-house 1-132 (329) Show / Hide 
Range on Protein: 66-202
Range on HMM: 1-132/329
Sequence Identity: 31% (43 aa)

YQIKTMIGRGTFCLVWLAYDYLRCENVAIKVLKRLYDDNQDDSQFEDELLMNLYLSGLDDTSKQITHFYDVFYYEDHCCFVLELVSQNILTFINYFDDIY
| .  ..|||||  |  .      | ||||.||.   .     | . |. .   ||...    ..  .|..|  . | | | |.  ||.  |    .  .
YEVLEFLGRGTFGQVVKCWKRGTNEMVAIKILKN---HPYYARQGQIEVSILHCLSQENADEYHFVRAYECFHHKNHTCLVFEMLEQNLYDFQK--QNKF

VPIPLKLIKKIVADTLKGLNFMHKNETIHTDLKPENV
 |.||| |. |.   |. |  . .   || ||||||.
MPLPLKHIRPILQQVLTALMKLKELGLIHADLKPENI
Kinase 82488.m00083.AA DYRK2 236-293 45 1.1e-17 53.82 In-house 144-202 (318) Show / Hide 
Range on Protein: 236-293
Range on HMM: 144-202/318
Sequence Identity: 45% (27 aa)

KLGDFGNSCFADN-ILNDLIQTRQYRSPEVLLGLPYTSSADIWSLACMTFELATRHHLF
|..||| |||..   .   ||.| ||.||| ||..|  . |.||. |   || | . ||
KVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYTGYPLF
Kinase 82488.m00083.AA DYRK 236-288 50 7.8e-16 55.87 In-house 147-199 (320) Show / Hide 
Range on Protein: 236-288
Range on HMM: 147-199/320
Sequence Identity: 50% (27 aa)

KLGDFGNSCFADNILNDLIQTRQYRSPEVLLGLPYTSSADIWSLACMTFELAT
|. ||| ||| .  .   || | ||.|||.||.||  . |.||| |   || |
KVIDFGSSCFEHQRIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAELFT
Kinase 82488.m00083.AA SRPK 142-202 38 1.5e-15 34.98 In-house 102-161 (554) Show / Hide 
Range on Protein: 142-202
Range on HMM: 102-161/554
Sequence Identity: 38% (24 aa)

HCCFVLELVSQNILTFINYFDDIYVPIPLKLIKKIVADTLKGLNFMHKN-ETIHTDLKPENV
| |.|.|.   | |  |  ..  |  .|. ..|.|.  .| || ..|     ||||.|||||
HYCMVFEVLGHNLLKWIKHYN--YQGMPMHCVKQIARQVLIGLDYLHRKCGIIHTDIKPENV
Kinase 82488.m00083.AA DYRK1 239-293 49 1.5e-14 47.08 In-house 149-203 (321) Show / Hide 
Range on Protein: 239-293
Range on HMM: 149-203/321
Sequence Identity: 49% (27 aa)

DFGNSCFADNILNDLIQTRQYRSPEVLLGLPYTSSADIWSLACMTFELATRHHLF
||| || ... .   || | |||||||||..|  . |.||| |.  |. |   ||
DFGSSCQLGQRIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMHTGEPLF
Kinase 82488.m00083.AA DYRK1 66-202 33 1.3e-13 43.69 In-house 1-135 (321) Show / Hide 
Range on Protein: 66-202
Range on HMM: 1-135/321
Sequence Identity: 33% (46 aa)

YQIKTMIGRGTFCLVWLAYDYLRCENVAIKVLKRLYDDNQDDSQFEDELLMNLYLSGLDDTSKQITHFYDVFYYEDHCCFVLELVSQNILTFINYFDDIY
|.| ..||.| |  |  ||| .. | ||||..|       .  | |  ||  |      .   .| |    | . .| | |.||.| |.   .   .  .
YEIDSLIGKGSFGQVVKAYDHQEQEYVAIKIIKN-KKPFYNQAQIEIRLL-ELMNKHDKEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTH--F

VPIPLKLIKKIVADTLKGLNFMHKNE--TIHTDLKPENV
  . | |..|.    .. | ||   |   || ||||||.
RGVSLNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENI
Kinase 82488.m00083.AA HIPK 236-286 44 3.3e-09 24.63 In-house 145-196 (329) Show / Hide 
Range on Protein: 236-286
Range on HMM: 145-196/329
Sequence Identity: 44% (23 aa)

KLGDFGN-SCFADNILNDLIQTRQYRSPEVLLGLPYTSSADIWSLACMTFEL
|  |||  | . . . |  .| | || ||..||||.  . |.||| |   ||
KVIDFGSASHVSKVVCNTYLQSRYYRAPEIILGLPFCENHDMWSLGCVIAEL
Kinase 82488.m00083.AA CAMK 383-403 47 5.8e-08 20.98 In-house 405-425 (425) Show / Hide 
Range on Protein: 383-403
Range on HMM: 405-425/425
Sequence Identity: 47% (10 aa)

MLAIIPKQRPTAEQLLDSPWL
||   |..|.|.|| |. ||.
MLQVDPEKRMTIEQCLNHPWM
Kinase 82488.m00083.AA STE 375-403 38 6.7e-07 20.54 In-house 329-359 (359) Show / Hide 
Range on Protein: 375-403
Range on HMM: 329-359/359
Sequence Identity: 38% (12 aa)

ELTEFLEPMLAIIPKQRPTAEQLLD--SPWL
|. .|..  | . |..||||.|||    |..
EFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 82488.m00083.AA TyrKc 66-401 13 9.5e-07 -113.53 SMART 1-280 (280) Show / Hide 
Range on Protein: 66-401
Range on HMM: 1-280/280
Sequence Identity: 13% (49 aa)

YQIKTMIGRGTFCLVWLAYDYLRCENVAIKVLKRLYDDNQDDSQFEDELLMNLYLSGL--DDTSKQITHFYDVFYYE-------DHCCFVLELVSQ-NIL
 . . ..|.| |. |...  .   ..||.|.||           | .|. .   .. |  .   . |  .| |   .       .  . |.|...  . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARI---MCKLGGHH--PNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK

TFINYFDDIYVPIPLKLIKKIVADTLKGLNFMHKNETIHTDLKPENVFAERPIFPYEPFSEDDTREVFNCLEDDESTINFKLGDFGNSCFADNI-----L
 .. .  .    ...|   ..  .  .| .. |..  || ||   |.   ..                            | .||| | . ..       
DYLRKHRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-------------------------TVKISDFGLSRDIYDDDQQGES

NDLIQTR---QYR--------SPEVLLGLPYTSSADIWSLACMTFELATRHHLFDPV-----LSDSDKEETPKNRDLFDAVHL----SMIESVLGQIPRD
 | . ..   . .        .||..    .|.  |.||   . .|. |.     |      .|...  |  |...  .  .     |            
KDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS------------

WARNGKLYPSLYNRHGELIATYHKQLPCLYNLLIKHGLNEQDAAELTEFLEPMLAIIPKQRPTAEQLLDSP
                                           .|. .  .   .  |..||| ... .  
-------------------------------------F-VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 82488.m00083.AA DYRK 364-403 25 5e-06 18.98 In-house 282-320 (320) Show / Hide 
Range on Protein: 364-403
Range on HMM: 282-320/320
Sequence Identity: 25% (10 aa)

IKHGLNEQDAAELTEFLEPMLAIIPKQRPTAEQLLDSPWL
...... .|  ... |.. .| . |..|.|..| |. ||.
WDPRHQ-CDDHQFKDFIKKCLQWDPHKRITPSQALQHPWF
Kinase 82488.m00083.AA Pkinase 375-403 48 1.2e-05 21.04 Pfam 265-293 (293) Show / Hide 
Range on Protein: 375-403
Range on HMM: 265-293/293
Sequence Identity: 48% (14 aa)

ELTEFLEPMLAIIPKQRPTAEQLLDSPWL
|. .|.. .|.  ||.||||||.| .||.
ECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 82488.m00083.AA CLK 369-403 22 0.000264 8.02 In-house 316-350 (350) Show / Hide 
Range on Protein: 369-403
Range on HMM: 316-350/350
Sequence Identity: 22% (8 aa)

NEQDAAELTEFLEPMLAIIPKQRPTAEQLLDSPWL
..... .| . .. || . | .|.|. . |. |. 
KDPEHRQLFDLIRKMLEYDPSKRITCKDALQHPFF
Kinase 82488.m00083.AA SRPK 66-98 36 0.001505 3.36 In-house 1-33 (554) Show / Hide 
Range on Protein: 66-98
Range on HMM: 1-33/554
Sequence Identity: 36% (12 aa)

YQIKTMIGRGTFCLVWLAYDYLRCENVAIKVLK
|..   .| | |  |||..|  .  .||.|. |
YHVIRKLGWGHFSTVWLCWDMQYDRYVAMKIVK
Kinase 82488.m00083.AA DYRK2 388-403 43 0.082347 1.29 In-house 303-318 (318) Show / Hide 
Range on Protein: 388-403
Range on HMM: 303-318/318
Sequence Identity: 43% (7 aa)

PKQRPTAEQLLDSPWL
|..| |..| |. ||.
PSERMTPSQALKHPWI