Gene 80213.m00062 (T.vaginalis)

80213.m00062

Species: T.vaginalis
Alias: TvagK0645, 80213.m00062
External Links:
Annotation:

Classification

Group: CMGC
Family: DYRK
Subfamily: DYRK2

Sequence

Name Sequence Type Origin Length Description Download
80213.m00062.AA Protein None 413 None Fasta, JSON
80213.m00062.kin_dom Protein Kinase Domain None 288 None Fasta, JSON

Protein domain

Protein domains of 80213.m00062.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 80213.m00062.AA DYRK 123-410 33 2.5e-88 299.77 In-house 1-320 (320) Show / Hide 
Range on Protein: 123-410
Range on HMM: 1-320/320
Sequence Identity: 33% (108 aa)

YQQIKELGRGAFGVVILCYDHKIHSLVAVKLVKDRPSMRNQITNEKEVNEAISRSSEPEASRFAKYFDYFKFRGFHVFVFEYLGTNLAYMLKYNRINGL-
|. .. .|.| || |. |.||| . .||.|... .... .|. .| .  | ...  . . ... ...|||..|...  ||| | .||   || |. .|. 
YEILEYIGKGSFGQVVKCWDHKTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQDPDDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNHFQGFF

KVNLIKIIGKQVAEALKFYHSI-NYIHCDIKPDNILWTDE-QHESIKLIDLGCTCKENQILHSCIQSRYYRAPEVILGCNYYNKIDVWSYGCLLSELYTG
 .||.. ...|. ..||| |.  |.||||.||.||.  .. .   ||.|| |  | |.| ... ||||.|||||||||| |. .||.|| || | ||.||
SLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLKQPRNKSTIKVIDFGSSCFEHQRIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAELFTG

SAIFQGENEQEQIGIYFSAIGRPHIKDLNDA--TRIDEFFNS---------NLYPK-TKSDGY-----------------SLEEILSCDNSNLLDLIKQC
  .|.||||..|.      .| |  . .. .  .|...||..             | |. ...                 ...  . || ....|.||.|
WPLFPGENEYDQLACIMEVLGMPPKWMIDKGRCRRKHKFFDCFMYCECDEWTKQNKITDHYMTPKCHPTKRGQRRPPGRRNWDPRHQCDDHQFKDFIKKC

LQWNPAKGPSMIEILNHPFF
|||.|.| ..  . |.||.|
LQWDPHKRITPSQALQHPWF
Kinase 80213.m00062.AA DYRK2 123-366 37 2.1e-71 231.35 In-house 1-250 (318) Show / Hide 
Range on Protein: 123-366
Range on HMM: 1-250/318
Sequence Identity: 37% (94 aa)

YQQIKELGRGAFGVVILCYDHKIHSLVAVKLVKDRPSMRNQITNEKEVNEAISRSSEPEASRFAKYFDYFKFRGFHVFVFEYLGTNLAYMLKYNRINGLK
|   . .|.| ||.|. ||||| . .||.|..  .    ||.  | .. ..|.|    ...   . .||| ||..|  .|| |..||.  .| |  .|. 
YEILEVIGKGSFGQVVKCYDHKTKQHVAIKMIRNKKRFHNQAYEEIRILHHIRRQDKDNTMNCVHMLDYFYFRNHHCITFELLSMNLYEYIKKNHFQGFS

VNLIKIIGKQVAEALKFYHSINYIHCDIKPDNILWTDEQHESIKLIDLGCTCKENQ-ILHSCIQSRYYRAPEVILGCNYYNKIDVWSYGCLLSELYTGSA
..|.   .... ..|.| |  | |||| || |||   .   .||.|| |  | |.|  ..  ||||.|||||||||. |   || || || . |||||  
LQLVRRFAHSILQCLRFLHKNNIIHCDLKPENILLKQWNRSGIKVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYTGYP

IFQGENEQEQIGIYFSAIGRPHIKDLNDA-----TRIDEFFNSNLYPKTK
.| ||||..|..     .| |  | .. .     .| . |||| .... .
LFPGENENDQFACMMEVLGMPPKKFFDTWFYIHCFRRKYFFNSHCFEWYC
Kinase 80213.m00062.AA CMGC 123-410 16 2.7e-69 226.56 In-house 1-513 (513) Show / Hide 
Range on Protein: 123-410
Range on HMM: 1-513/513
Sequence Identity: 16% (86 aa)

YQQIKELGRGAFGVVILCYD--------------HKIHSLVAVKLVKDRPSMRNQ-----------ITNEKEVNE--AISRSSEPEA-----------SR
|. || .|.|..|||  |.|              |.   .||.| .| .. . .|           |.   |.     ...  .|               
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDP-NWQRRDDPDNKHHN

-FAKYFDYFKFRG-----------------FHVFVFEYLGTNLAYMLKYNR--------------------------INGLKVNLIKIIGKQVAEALK--
   | .|.|....                    .||||....|. ..| |.                          |  . . .|. . .|. ..||  
NIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLK

FYHSIN--YIHCDIKPDNILWTDEQHE------------------SIKLIDLGCTCKENQ------------------------ILHSCIQSRYYRAPEV
. || .   ||.|.|| ||| ...                      .|..| |  .....                         . . ...|.|||||.
YCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEI

ILGCNYY----------NKIDVWSYGCLLSELYTG--------SAIFQGENE-----------QEQIGIYFSAIGRPH---------------IKDLNDA
.||. .|           .||.|| || . |.|||          .|.|..|           ..|.   |  .| |                 ..  . 
LLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNM

TR-------------------IDEFFNSNLYP---KTKSDGYSLEEILSC-----------------------------------DNSNLLDLIKQCLQW
.                    ..||    . .   . .  . .....  .                                   ... ..||.|..||.
IKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQY

NPAKGPSMIEILNHPFF
.|.| ..  ..|.||.|
DPDKRITAEQALQHPYF
Kinase 80213.m00062.AA S_TKc 123-410 24 4e-61 210.28 SMART 1-231 (231) Show / Hide 
Range on Protein: 123-410
Range on HMM: 1-231/231
Sequence Identity: 24% (74 aa)

YQQIKELGRGAFGVVILCYDHKIHSLVAVKLVKDRPSMRNQITNEKEVNEAISRSSEPEASRFAKYFDYFKFRGFHVFVFEYLGT---NLAYMLKYNRIN
|. ....|.||||.| .|...| . .||.| .|      ..| .| .. .              |..|.|   ..  .|.||...   .|  ..| .. .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

G----LKVNLIKIIGKQVAEALKFYHSINYIHCDIKPDNILWTDEQHESIKLIDLGCTCKENQILHSCIQSRYYRAPEVILGCNYYN-KIDVWSYGCLLS
|    .    .. . .|...||.. || . ||.|.||.||| ..     ||..| |  ..     .... ...|.||||.    |   |.|.|| ||.| 
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELYTGSAIFQGENEQEQIGIYFSAIGRPHIKDLNDATRIDEFFNSNLYPKTKSDGYSLEEILSCDNSNLLDLIKQCLQWNPAKGPSMIEILN-------H
|...|   |.      |.   |  ||                                        . ..|.|..|||..|.| |.  |.|.       |
EMLCGYPPFP------QMQMMFKKIG---------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCH

PFF
|.|
PWF
Kinase 80213.m00062.AA DYRK1 123-358 34 1.5e-50 174.28 In-house 1-238 (321) Show / Hide 
Range on Protein: 123-358
Range on HMM: 1-238/321
Sequence Identity: 34% (81 aa)

YQQIKELGRGAFGVVILCYDHKIHSLVAVKLVKDRPSMRNQITNEKEVNEAISRSSEPEASRFAKYFDYFKFRGFHVFVFEYLGTNLAYMLKYNRINGLK
|. .  .|.|.|| |.  |||. . .||.|..| . .  ||   |  . | . .  . .  .  .    |.||     ||| |  ||  .|.     |  
YEIDSLIGKGSFGQVVKAYDHQEQEYVAIKIIKNKKPFYNQAQIEIRLLELMNKHDKEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVS

VNLIKIIGKQVAEALKFYHS--INYIHCDIKPDNILWTDEQHESIKLIDLGCTCKENQILHSCIQSRYYRAPEVILGCNYYNKIDVWSYGCLLSELYTGS
.||.. . .|.. || |  .  .. ||||.||.|||    .   ||.|| |  |. .| .   ||||.||.|||.|| .|  .||.|| ||.| |. || 
LNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENILLCNPKRSAIKIIDFGSSCQLGQRIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMHTGE

AIFQGENEQEQIGIYFSAIGRPHIKDLNDATRIDEFFN
 .| | ||..|.      .| |  . .. | .   .|.
PLFSGSNEVDQMNKIVEVLGMPPKHMIDQAPKAHKYFE
Kinase 80213.m00062.AA HIPK 123-358 31 4e-47 146.18 In-house 1-238 (329) Show / Hide 
Range on Protein: 123-358
Range on HMM: 1-238/329
Sequence Identity: 31% (75 aa)

YQQIKELGRGAFGVVILCYDHKIHSLVAVKLVKDRPSMRNQITNEKEVNEAISRSSEPEASRFAKYFDYFKFRGFHVFVFEYLGTNLAYMLKYNRINGLK
|  .  |||| || |. |  .  . .||.|. |. |.   |. .| .. . . .. ...   | . ...|. .     ||| |  ||   .| |.   | 
YEVLEFLGRGTFGQVVKCWKRGTNEMVAIKILKNHPYYARQGQIEVSILHCL-SQENADEYHFVRAYECFHHKNHTCLVFEMLEQNLYDFQKQNKFMPLP

VNLIKIIGKQVAEALKFYHSINYIHCDIKPDNILWTDEQHES--IKLIDLGCTCKENQILHSC-IQSRYYRAPEVILGCNYYNKIDVWSYGCLLSELYTG
.. |. | .||. ||.   ..  || |.||.||.  |...    .| || |      ..  .  .|||||||||.|||  .  ..|.|| || . ||. |
LKHIRPILQQVLTALMKLKELGLIHADLKPENIMLVDPTRCPYRVKVIDFGSASHVSKVVCNTYLQSRYYRAPEIILGLPFCENHDMWSLGCVIAELFLG

SAIFQGENEQEQIGIYFSAIGRPHIKDLNDATRIDEFFN
   . | .| .||  .    . ||   |. |..   ||.
WPLYPGADEYDQIRYICQTQHLPHEHLLHAACKKHRFFD
Kinase 80213.m00062.AA DyrkP 123-329 36 2.7e-41 133.33 In-house 1-211 (323) Show / Hide 
Range on Protein: 123-329
Range on HMM: 1-211/323
Sequence Identity: 36% (76 aa)

YQQIKELGRGAFGVVILCYDHKIHSLVAVKLVKDRPSMRNQITNEKEVNEAISRSSEPEASRFAKYFDYFKFRGFHVFVFEYLGTNLAYMLKYNRINGLK
|| .  ||  ||   | | | .   .. .|..        |   |  .   |    . .     .|.|||  .     . | |  ||    |.|| |  .
YQIMEYLGSAAFSKAIQCQDKQTNQMMCMKIIENNKDYFDQSIDEIKLLRYINYNGDVDEKNVLRYYDYFYHKEHLFIITELLKDNLYEFYKFNRENEQQ

----VNLIKIIGKQVAEALKFYHSINYIHCDIKPDNILWTDEQHESIKLIDLGCTCKENQILHSCIQSRYYRAPEVILGCNYYNKIDVWSYGCLLSELYT
    |  .. | .|.  || . ||.  ||||.||.|||        .|.|| |  |     | | .||| |||||||.|| |  .||.|| ||.| ||.|
RYFTVGRLQKITQQILIALDYIHSLRLIHCDLKPENILMKSYPKCQVKIIDFGSSCFIHDHLSSYVQSRSYRAPEVIIGCKYDYRIDMWSLGCILAELWT

GSAIFQGENEQ
|  .|| .| |
GNVLFQNDNIQ
Kinase 80213.m00062.AA Pkinase 200-410 27 3.1e-39 139.81 Pfam 77-293 (293) Show / Hide 
Range on Protein: 200-410
Range on HMM: 77-293/293
Sequence Identity: 27% (62 aa)

FVFEYLGT-----NLAYMLK---YNRINGLKVNLIKIIGKQVAEALKFYHSINYIHCDIKPDNILWTDEQHE--SIKLIDLGCTCK---ENQILHSCIQS
.|.||..       |. ...   ....  .  . .| . .|....|.. || . ||.|.||.|||  .. |   ..|..| |. ..    |. ...   .
MVMEYCEGGLYVMDLFDYISTWRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDYNNS-MTTFCGT

RYYRAPEVIL-GCNYYNKIDVWSYGCLLSELYTGSAIFQGE----NEQEQIGIYFSAIGRPHIKDLNDATRIDEFFNSNLYPKTKSDGYSLEEILSCDNS
..|.|||||. |  |  |.|.||.||.| |...|  .|.|.    |  .|. ...   |.|   |     .|  ||  .  . .      ...     ..
PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H----F-HWTF-HNWSE

NLLDLIKQCLQWNPAKGPSMIEILNHPFF
...|.|| ||...|.| |.  .||.||.|
ECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 80213.m00062.AA YAK 123-332 34 4.7e-39 130.08 In-house 1-214 (347) Show / Hide 
Range on Protein: 123-332
Range on HMM: 1-214/347
Sequence Identity: 34% (73 aa)

YQQIKELGRGAFGVVILCYDHKIHSLVAVKLVKDRPSMRNQITNEKEVNEAISRSSEPEASR----FAKYFDYFKFRGFHVFVFEYLGTNLAYMLKYNRI
|     ||.| || |. |       |.||| .| |.    |  ||  . .      .|.       . .  |.| ..     ||| |  ||   || |. 
YIVLDMLGQGTFGQVVKCQNCDTNELFAVKVIKNRQAYFQQAKNEIQILRVLNQQHDPNNKNYQKHILRMYDFFVHKNHFCLVFEMLSNNLYEYLKQNKF

NGLKVNLIKIIGKQVAEALKFYHSINYIHCDIKPDNILWTDEQHESIKLIDLGCTCKENQILHSCIQSRYYRAPEVILGCNYYNKIDVWSYGCLLSELYT
 |. ..||.   ||. ...    . . |||| || ||.        ||.|| |  |.| . .   ||.|.||.||.|..  |   || || || . ||. 
CGFSFQLIRQWTKQILDGMCVLENKQIIHCDLKPENIMLCKPNKPEIKIIDFGSSCQEKKMVYTYIQQRHYRSPEIIVWMIYCTSIDMWSLGCIVAELFL

GSAIFQGENEQEQI
|  || |  | .||
GLPIFPGNSEYNQI
Kinase 80213.m00062.AA CDK 199-410 23 1.1e-37 118.03 In-house 94-284 (284) Show / Hide 
Range on Protein: 199-410
Range on HMM: 94-284/284
Sequence Identity: 23% (55 aa)

VFVFEYLGTNLAYMLKYNRINGLKVNLIKIIGKQVAEALKFYHSINYIHCDIKPDNILWTDEQHES---IKLIDLGCTCKEN---------QILHSCIQS
..||||. . |.  ..           || . .|  ..| . || . .| |.|| ||| ..  ..    .|. | |  .. .         . . . .  
YMVFEYMDHDLKKYMD-----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVT

RYYRAPEVILGCNYYN---KIDVWSYGCLLSELYT---GSAIFQGENEQEQIGIYFSAIGRPHIKDLNDATRIDEFFNSNLYPKTKSDGYSLEEILSCDN
. |||||. ||.  |.    ||.|| || ..|..|   . ..|.|..|..|.   |  .| |  ..  . |   ..                        
LWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY------------------------

SNLLDLIKQCLQWNPAKGPSMIEILNHPFF
    ||. ..|. .|.|  |  . |.||.|
----DLLNKMLCYDPKKRISAEQALQHPYF
Kinase 80213.m00062.AA PRP4 123-325 33 4e-32 113.03 In-house 1-207 (320) Show / Hide 
Range on Protein: 123-325
Range on HMM: 1-207/320
Sequence Identity: 33% (70 aa)

YQQIKELGRGAFGVVILCY-DHKIHSLVAVKLVKDRPSMRNQITNEKEVNEAISRS--SEPEASRFAKYFDYFKFRGFHVFVFEYLGTNLAYMLK-YNRI
|. .   | | |. |. |    .    ||.| .  ...|.     |.|.   ..    .  . .   . |. |..|     ||| .  ||  .|| | . 
YRVYGYCGQGVFSNVCRCRDQTRGNEMVAIKIIRNNEIMHKTGLRELEILQKLNDAPTDKNDKFHCVRMFRHFNHRQHMCLVFECMSMNLREVLKKYGKD

NGLKVNLIKIIGKQVAEALKFYHSINYIHCDIKPDNILWTDEQHESIKLIDLGC--TCKENQILHSCIQSRYYRAPEVILGCNYYNKIDVWSYGCLLSEL
 || .. .    .|   |||     |..| ||||||||   |  . .|..| |     .|| |     .||.|||||.|.| .|.. ||.|| || | ||
VGLHLKAVRSYAQQLFLALKHLKKCNILHADIKPDNIL-VNESKNTLKMCDFGSASHIHENEITP-YLVSRFYRAPEIIIGHPYDYQIDMWSVGCTLYEL

YTGSAIFQG
|||  .| |
YTGKIMFPG
Kinase 80213.m00062.AA CLK 123-267 27 2.2e-20 57.14 In-house 1-159 (350) Show / Hide 
Range on Protein: 123-267
Range on HMM: 1-159/350
Sequence Identity: 27% (43 aa)

YQQIKELGRGAFGVVILCYDHKI-HSLVAVKLVKDRPSMRNQITNEKE-VNEAISRSSEPEASRF---AKYFDYFKF-RGFHVFVFEYLGTNLAYMLKYN
|  .. || |.|| |  | |||   ..||.| ..     | .   | . . ..|    .|.  .     | .|.|..  |    ||| .| ..   .| |
YEIVCTLGEGTFGKVVECWDHKNGKKYVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFDYGHGHICIVFELYGLSIYDFMKSN

R------INGLKVNLIKIIGKQVAEALKFYHSINYIHCDIKPDNILWTDE--QHESIKL
.      . ... . |. ...|  ||.|| |..  .| | || ||. .|.  .| . ..
NSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHDMKLTHTDLKPENICFVDSRFTHFDCTF
Kinase 80213.m00062.AA CLK 284-330 53 1.8e-19 54.36 In-house 208-254 (350) Show / Hide 
Range on Protein: 284-330
Range on HMM: 208-254/350
Sequence Identity: 53% (25 aa)

IQSRYYRAPEVILGCNYYNKIDVWSYGCLLSELYTGSAIFQGENEQE
...| |||||||||. .  . |||| || |.|||||   ||. .. |
VSTRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLFQTHDNRE
Kinase 80213.m00062.AA TyrKc 123-410 19 1.1e-10 -49.69 SMART 1-280 (280) Show / Hide 
Range on Protein: 123-410
Range on HMM: 1-280/280
Sequence Identity: 19% (63 aa)

YQQIKELGRGAFGVVILCYDHKIHSLVAVKLVKDRPSMRNQITNEKEVNEAISRSSEPEASRFAKY------------FDYFKFR-----GFHVFVFEYL
 . .|.||.||||.| ..        |||| .|.               |.. |    ||.   |.                ..|     . .  |.|| 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------------REDFMR----EARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYM

-GTNLAYMLKYNRINGLKVNLIKIIGKQVAEALKFYHSINYIHCDIKPDNILWTDEQHESIKLIDLGCTCKENQI--------LHSC---IQSR-----Y
 . .|   |...| . |..     .  |.|.   . || |.|| |.   |.| ....   .|  | | . .              .     ...      
PHGDLKDYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIR

YRAPEVILGCNYYNKIDVWSYGCLLSELYTGSAIFQGE-----NEQEQIGIYFSAIGRPHIKDL----NDATRIDEFFNSNLYPKTKSDGYSLEEILSCD
  |||.|  . .  | ||||.| .. |..|  .    .      . ...  |  . .|. . .                            .      | 
WMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS----------------------F-----VCC

NSNLLDLIKQCLQWNPAKGPSMIEILNHPFF
 . . ...||| . .|.. |.. ||  | .|
PDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 80213.m00062.AA DYRK2 371-410 31 1.3e-08 23.78 In-house 278-318 (318) Show / Hide 
Range on Protein: 371-410
Range on HMM: 278-318/318
Sequence Identity: 31% (13 aa)

SLEEILS-CDNSNLLDLIKQCLQWNPAKGPSMIEILNHPFF
|. ..|  |.  |..| ||.|..| |..  .  ..|.||..
SWKSVLKGCEDENFIDFIKRCFEWDPSERMTPSQALKHPWI
Kinase 80213.m00062.AA CLK 371-410 30 1.6e-08 20.93 In-house 311-350 (350) Show / Hide 
Range on Protein: 371-410
Range on HMM: 311-350/350
Sequence Identity: 30% (12 aa)

SLEEILSCDNSNLLDLIKQCLQWNPAKGPSMIEILNHPFF
.. .. . .   | |||...|   |.| ..  ..| ||||
QYMDCKDPEHRQLFDLIRKMLEYDPSKRITCKDALQHPFF
Kinase 80213.m00062.AA Pkinase 123-155 36 1.8e-07 27.48 Pfam 1-33 (293) Show / Hide 
Range on Protein: 123-155
Range on HMM: 1-33/293
Sequence Identity: 36% (12 aa)

YQQIKELGRGAFGVVILCYDHKIHSLVAVKLVK
|. .. .|.|.||.| .|....   .|||| .|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIK
Kinase 80213.m00062.AA CDK 123-155 26 1.9e-07 19.74 In-house 1-38 (284) Show / Hide 
Range on Protein: 123-155
Range on HMM: 1-38/284
Sequence Identity: 26% (10 aa)

YQQIKELGRGAFGVVILCYDHKIH-----SLVAVKLVK
|......|.|..|||  . |.. .      .|| | ..
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIR
Kinase 80213.m00062.AA DyrkP 384-410 40 1.7e-05 13.29 In-house 297-323 (323) Show / Hide 
Range on Protein: 384-410
Range on HMM: 297-323/323
Sequence Identity: 40% (11 aa)

LDLIKQCLQWNPAKGPSMIEILNHPFF
.| ..||||    . |.  | |.||.|
IDFVRQCLQIDFTRRPTAKEALQHPWF
Kinase 80213.m00062.AA PRP4 385-410 42 5.2e-05 14.37 In-house 295-320 (320) Show / Hide 
Range on Protein: 385-410
Range on HMM: 295-320/320
Sequence Identity: 42% (11 aa)

DLIKQCLQWNPAKGPSMIEILNHPFF
||. .||.  |.|  .. | | |||.
DLLDKCLMLDPKKRITCNEALKHPFI
Kinase 80213.m00062.AA DYRK1 379-410 37 0.000107 11.86 In-house 290-321 (321) Show / Hide 
Range on Protein: 379-410
Range on HMM: 290-321/321
Sequence Identity: 37% (12 aa)

DNSNLLDLIKQCLQWNPAKGPSMIEILNHPFF
| .   ||||. ||..|..  .  ..| |.||
DYLKFKDLIKRMLQYDPKQRITPYYALQHSFF
Kinase 80213.m00062.AA Pkinase_Tyr 123-156 34 0.000209 15.55 Pfam 1-38 (270) Show / Hide 
Range on Protein: 123-156
Range on HMM: 1-38/270
Sequence Identity: 34% (13 aa)

YQQIKELGRGAFGVVILCYDH----KIHSLVAVKLVKD
 . .|.||.||||.| ... .    . .  |||| .|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE
Kinase 80213.m00062.AA Pkinase_Tyr 291-318 46 0.002006 12.22 Pfam 182-209 (270) Show / Hide 
Range on Protein: 291-318
Range on HMM: 182-209/270
Sequence Identity: 46% (13 aa)

APEVILGCNYYNKIDVWSYGCLLSELYT
|||.|  . .  | ||||.| |. |..|
APECINYGKFTTKSDVWSFGVLMWEIFT
Kinase 80213.m00062.AA HIPK 379-410 31 0.007075 4.34 In-house 298-329 (329) Show / Hide 
Range on Protein: 379-410
Range on HMM: 298-329/329
Sequence Identity: 31% (10 aa)

DNSNLLDLIKQCLQWNPAKGPSMIEILNHPFF
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DRREFVHVLKKMCTWDAHKRITPCEALNHPFV
Kinase 80213.m00062.AA YAK 383-410 35 0.05759 2.02 In-house 320-347 (347) Show / Hide 
Range on Protein: 383-410
Range on HMM: 320-347/347
Sequence Identity: 35% (10 aa)

LLDLIKQCLQWNPAKGPSMIEILNHPFF
..|.| | || || .  .      ||| 
FIDFINQLLQLNPRERWKPMQAMQHPFI
Kinase 80213.m00062.AA Pkinase_Tyr 229-250 31 2.650423 1.65 Pfam 116-137 (270) Show / Hide 
Range on Protein: 229-250
Range on HMM: 116-137/270
Sequence Identity: 31% (7 aa)

IGKQVAEALKFYHSINYIHCDI
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MCWQIAKGMEYLESKNCIHRDL