81909.m00091

Species: T.vaginalis
Alias: TvagK0648, 81909.m00091
External Links:
Annotation:

Classification

Group: CMGC
Family: DYRK
Subfamily: DYRK2

Sequence

Name Sequence Type Origin Length Description Download
81909.m00091.AA Protein None 433 None Fasta, JSON
81909.m00091.kin_dom Protein Kinase Domain None 288 None Fasta, JSON

Protein domain

Protein domains of 81909.m00091.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 81909.m00091.AA DYRK 143-430 33 2.4e-84 286.52 In-house 1-320 (320) Show / Hide
Range on Protein: 143-430
Range on HMM: 1-320/320
Sequence Identity: 33% (107 aa)

YQQIVEICRGNFGSVLKCYDHKTKKIVAVKLIKDRPKIHKQILMEKVALDMIQEADPKFTHFIVPVIDKFYFRGFHCFCFELLWKDTYTCQKDENFVGY-
|. .  | .| || | ||.||||...||.|.|. ... |.|.. |   |. . ..||  .. .|   | ||.|...|  ||||  . |   |  .| |. 
YEILEYIGKGSFGQVVKCWDHKTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQDPDDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNHFQGFF

EDGLLKTVSKQICDSLIFFHSL-GLVHCDIKPENIVWTND-QKTTVNLIDFGCCCHEGNPLFKYMQSRFYRAPEVILHISFTRAIDVWSFGLVIIELKLG
   | ... .||...| | |..  ..|||.|||||.  .  .| |. .||||  |.|.  ...| |||||||||||| . .  |||.||.| .. || .|
SLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLKQPRNKSTIKVIDFGSSCFEHQRIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAELFTG

HPLYAGNNEKEQLGMYYSSLGPPDEKYLRSS--PRFSEFFGD------------DA----------------SIKNEYSYPLFDELVVGLDPDLVDLVRK
.||..|.|| .|| .    ||.| .. ....  .|  .|| .            .                 ...   . .. ...    | ...|...|
WPLFPGENEYDQLACIMEVLGMPPKWMIDKGRCRRKHKFFDCFMYCECDEWTKQNKITDHYMTPKCHPTKRGQRRPPGRRNWDPRHQ-CDDHQFKDFIKK

CLEWDPNKRIKMTEVLKHPYL
||.|||.|||.  . |.|| .
CLQWDPHKRITPSQALQHPWF

Kinase 81909.m00091.AA DYRK2 143-377 39 2.8e-66 214.43 In-house 1-241 (318) Show / Hide
Range on Protein: 143-377
Range on HMM: 1-241/318
Sequence Identity: 39% (96 aa)

YQQIVEICRGNFGSVLKCYDHKTKKIVAVKLIKDRPKIHKQILMEKVALDMIQEADPKFTHFIVPVIDKFYFRGFHCFCFELLWKDTYTCQKDENFVGYE
|     | .| ||.|.||||||||. ||.|.|  . . |.|...|   |. | . |.  |. .|   | ||||..||  ||||  . |   |  .| |. 
YEILEVIGKGSFGQVVKCYDHKTKQHVAIKMIRNKKRFHNQAYEEIRILHHIRRQDKDNTMNCVHMLDYFYFRNHHCITFELLSMNLYEYIKKNHFQGFS

DGLLKTVSKQICDSLIFFHSLGLVHCDIKPENIVWTNDQKTTVNLIDFGCCCHEGN-PLFKYMQSRFYRAPEVILHISFTRAIDVWSFGLVIIELKLGHP
  |     ..|  .| | |   ..||| |||||.     . .. .||||  | |   ... | |||||||||||| . .  ||| |||| .. ||  |.|
LQLVRRFAHSILQCLRFLHKNNIIHCDLKPENILLKQWNRSGIKVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYTGYP

LYAGNNEKEQLGMYYSSLGPPDEKYLRSS-----PRFSEFF
| .| ||..|...    || |..| .  .      |   ||
LFPGENENDQFACMMEVLGMPPKKFFDTWFYIHCFRRKYFF

Kinase 81909.m00091.AA DYRK1 143-377 35 5.5e-61 208.92 In-house 1-237 (321) Show / Hide
Range on Protein: 143-377
Range on HMM: 1-237/321
Sequence Identity: 35% (84 aa)

YQQIVEICRGNFGSVLKCYDHKTKKIVAVKLIKDRPKIHKQILMEKVALDMIQEADPKFTHFIVPVIDKFYFRGFHCFCFELLWKDTYTCQKDENFVGYE
|. .  | .| || | | |||.... ||.|.|| .     | ..|   |... ..|.     || .   | ||   |  ||||    |   .  .| |  
YEIDSLIGKGSFGQVVKAYDHQEQEYVAIKIIKNKKPFYNQAQIEIRLLELMNKHDKEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVS

DGLLKTVSKQICDSLIFFHS--LGLVHCDIKPENIVWTNDQKTTVNLIDFGCCCHEGNPLFKYMQSRFYRAPEVILHISFTRAIDVWSFGLVIIELKLGH
  | .   .|.| .|.|. .  | ..|||.|||||.  | ..  . .||||  |. |. ...|.||||||.|||.| |..  |||.|| | ...|.  | 
LNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENILLCNPKRSAIKIIDFGSSCQLGQRIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMHTGE

PLYAGNNEKEQLGMYYSSLGPPDEKYLRSSPRFSEFF
||..| || .|.      || | .. . ..|.   .|
PLFSGSNEVDQMNKIVEVLGMPPKHMIDQAPKAHKYF

Kinase 81909.m00091.AA CMGC 143-430 17 1.1e-59 194.37 In-house 1-513 (513) Show / Hide
Range on Protein: 143-430
Range on HMM: 1-513/513
Sequence Identity: 17% (92 aa)

YQQIVEICRGNFGSVLKCYD--------------HKTKKIVAVKLIKDRPKIHKQ-------------ILMEKVALDMIQEADPKFT-----------HF
|. |  | .| .| | ||.|              |.|..|||.| || ..  . |             .| |   | ...... .             | 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDP-NWQRRDDPDNKHHN

-IVPVIDKFYFRG-----------------FHCFCFELLWKDTYTCQKDENF-------VGYEDGL------------LKTVS------KQICDSLI--F
 ||  .| ||...                   .. ||.. .| |   |. .|       .. ..               |  .      .||. .|   .
NIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKY

FHSLG--LVHCDIKPENIVWTND------------------QKTTVNLIDFGCCCHEGNP------------------------LFKYMQSRFYRAPEVI
 || .   .|.|.|||||  ...                  .. .. ..||| .......                        .  | ..|.|||||..
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEIL

LHIS----------FTRAIDVWSFGLVIIELKLG--------HPLYAGNNE-----------KEQLGMYYSSLGPPDEKYLRS-------SPRFSEFFGD
|  .          .| .||.||.| .. |. .|        .||  |..|            .|| .    ||.|. . ...       ...  |... 
LGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGKRHFNFCKHEEEWPNM

DA--------------------SI-----------KNEYSYPLFDELVVG-----------------------------------LDPDLVDLVRKCLEW
                      |.           . .. .. . .|. .                                   .||...||. |.|..
IKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQY

DPNKRIKMTEVLKHPYL
||.|||.  . |.|||.
DPDKRITAEQALQHPYF

Kinase 81909.m00091.AA S_TKc 143-430 24 4.6e-52 180.2 SMART 1-231 (231) Show / Hide
Range on Protein: 143-430
Range on HMM: 1-231/231
Sequence Identity: 24% (73 aa)

YQQIVEICRGNFGSVLKCYDHKTKKIVAVKLIKDRPKIHKQILMEKVALDMIQEADPKFTHFIVPVIDKFYFRGFHCFCFELLWK---DTYTCQKDENFV
|. . .| .| ||.| ||...||..|||.| ||      ..|. |   | .          .||  .| |.  .. ....|..     | ..  |. .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

G----YEDGLLKTVSKQICDSLIFFHSLGLVHCDIKPENIVWTNDQKTTVNLIDFGCCCHEGNPLFKYMQSRFYRAPEVILHISFTR-AIDVWSFGLVII
|    .     . . .|||. | . ||.| .|.|.|||||  ..    .. ..||| ...       .  ...|.||||.   .... ..|.||.| ...
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELKLGHPLYAGNNEKEQLGMYYSSLGPPDEKYLRSSPRFSEFFGDDASIKNEYSYPLFDELVVGLDPDLVDLVRKCLEWDPNKRIKMTEVLK-------H
|.  | |..       |. | .  .|                                       .|.. |..||||..||.||.   |.|.       |
EMLCGYPPFP------QMQMMFKKIG---------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCH

PYL
|..
PWF

Kinase 81909.m00091.AA HIPK 143-384 33 1.4e-47 147.59 In-house 1-244 (329) Show / Hide
Range on Protein: 143-384
Range on HMM: 1-244/329
Sequence Identity: 33% (81 aa)

YQQIVEICRGNFGSVLKCYDHKTKKIVAVKLIKDRPKIHKQILMEKVALDMIQEADPKFTHFIVPVIDKFYFRGFHCFCFELLWKDTYTCQKDENFVGYE
|  .  . || || | ||  . |. .||.|..|. |   .|. .|   |  ... ..   ||.    . |  .   |  ||.|    |  ||. .|    
YEVLEFLGRGTFGQVVKCWKRGTNEMVAIKILKNHPYYARQGQIEVSILHCLSQENADEYHFVR-AYECFHHKNHTCLVFEMLEQNLYDFQKQNKFMPLP

DGLLKTVSKQICDSLIFFHSLGLVHCDIKPENIVWTNDQKT--TVNLIDFGCCCHEGNPLFK-YMQSRFYRAPEVILHISFTRAIDVWSFGLVIIELKLG
   .... .|.   |.   .|||.| |.|||||     ..    |  ||||   |  .   . |.|||.|||||.|| . |  ..|.|| | || || ||
LKHIRPILQQVLTALMKLKELGLIHADLKPENIMLVDPTRCPYRVKVIDFGSASHVSKVVCNTYLQSRYYRAPEIILGLPFCENHDMWSLGCVIAELFLG

HPLYAGNNEKEQLGMYYSSLGPPDEKYLRSSPRFSEFFGDDASIK
 ||| |..| .|   .    . | |  | .  .   ||  |  .|
WPLYPGADEYDQIRYICQTQHLPHEHLLHAACKKHRFFDRDKQSK

Kinase 81909.m00091.AA Pkinase 143-430 24 3.6e-45 160.81 Pfam 1-293 (293) Show / Hide
Range on Protein: 143-430
Range on HMM: 1-293/293
Sequence Identity: 24% (78 aa)

YQQIVEICRGNFGSVLKCYDHKTKKIVAVKLIKDRPKIHKQILMEKVA---LDMIQEADPKFTHFIVPVIDKFYFRGFHCFCFELLWK-----DTY----
|. .  | .|.||.| ||....| |||||| || | ..... .....    . . .. .     .||  .| |. ..  ....|.. .     | .    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLN---HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIS

TCQKDENFVGYEDGLLKTVSKQICDSLIFFHSLGLVHCDIKPENIVWTNDQKT--TVNLIDFGCCCH--EGNPLFKYMQ--SRFYRAPEVIL-HISFTRA
| ... .|   ..  .| . .||.  | . || | .|.|.|||||   |.  .  .| ..|||....  . |    .    ...|.|||||. .   ...
T-WRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

IDVWSFGLVIIELKLGHPLYAGN----NEKEQLGMYYSSLG---PPDEKYLRSSPRFSEFFGDDASIKNEYSYPLFDELVVGLDPDLVDLVRKCLEWDPN
.|.||.|....|. .|.|.. |     |  .|. |..  .|   . |. ...| ..|. |.  . .       . . .. . ..... |....||..||.
VDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-------F-HWTF-HNWSEECKDFIKWCLCKDPK

KRIKMTEVLKHPYL
||.  ...|.||..
KRPTAEQILQHPWF

Kinase 81909.m00091.AA YAK 146-352 34 1.4e-43 145.75 In-house 2-214 (347) Show / Hide
Range on Protein: 146-352
Range on HMM: 2-214/347
Sequence Identity: 34% (74 aa)

IVE--ICRGNFGSVLKCYDHKTKKIVAVKLIKDRPKIHKQILMEKVALDMI-QEADPKFTH---FIVPVIDKFYFRGFHCFCFELLWKDTYTCQKDENFV
||.    .| || | ||    |. ..||| || |.    |   |   | .  |  ||   .    |.  .| | ..   |  ||.|    |   |  .| 
IVLDMLGQGTFGQVVKCQNCDTNELFAVKVIKNRQAYFQQAKNEIQILRVLNQQHDPNNKNYQKHILRMYDFFVHKNHFCLVFEMLSNNLYEYLKQNKFC

GYEDGLLKTVSKQICDSLIFFHSLGLVHCDIKPENIVWTNDQKTTVNLIDFGCCCHEGNPLFKYMQSRFYRAPEVILHISFTRAIDVWSFGLVIIELKLG
|    | ..  ||| |...   .  ..||| |||||   .  |  . .||||  | |   . .| |.|.||.||.|. . .. .|| || | .. || ||
GFSFQLIRQWTKQILDGMCVLENKQIIHCDLKPENIMLCKPNKPEIKIIDFGSSCQEKKMVYTYIQQRHYRSPEIIVWMIYCTSIDMWSLGCIVAELFLG

HPLYAGNNEKEQL
 |.. || | .|.
LPIFPGNSEYNQI

Kinase 81909.m00091.AA CLK 143-275 30 4.1e-22 62.44 In-house 1-145 (350) Show / Hide
Range on Protein: 143-275
Range on HMM: 1-145/350
Sequence Identity: 30% (44 aa)

YQQIVEICRGNFGSVLKCYDHKT-KKIVAVKLIKDRPKIHKQILMEKV-ALDMIQEA-DPKFTHF--IVPVIDKFYF-RGFHCFCFELLWKDTYTCQKDE
|  .     | || |..| |||  || ||.| |.   |   .   |    .  |.|. ||  ..   ..  .| | .  |  |  |||. . .|   |. 
YEIVCTLGEGTFGKVVECWDHKNGKKYVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFDYGHGHICIVFELYGLSIYDFMKSN

N------FVGYEDGLLKTVSKQICDSLIFFHSLGLVHCDIKPENI
|      . .|.    .  ..|.| .. | |...|.| | |||||
NSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHDMKLTHTDLKPENI

Kinase 81909.m00091.AA PRP4 263-336 42 6.9e-20 69.52 In-house 125-198 (320) Show / Hide
Range on Protein: 263-336
Range on HMM: 125-198/320
Sequence Identity: 42% (32 aa)

LGLVHCDIKPENIVWTNDQKTTVNLIDFGCCCH-EGNPLFKYMQSRFYRAPEVILHISFTRAIDVWSFGLVIIEL
.. .| |||| ||.  |  |.|  ..|||   | . | . .| .||||||||.|. ...  .||.|| |  . ||
CNILHADIKPDNIL-VNESKNTLKMCDFGSASHIHENEITPYLVSRFYRAPEIIIGHPYDYQIDMWSVGCTLYEL

Kinase 81909.m00091.AA RCK 251-348 32 3.5e-18 54.03 In-house 112-219 (298) Show / Hide
Range on Protein: 251-348
Range on HMM: 112-219/298
Sequence Identity: 32% (35 aa)

KQICDSLIFFHSLGLVHCDIKPENIVWTND-------QKTTVNLIDFGCC-CHEGNP-LFKYMQSRFYRAPEVILHI-SFTRAIDVWSFGLVIIELKLGH
.||. .| . |. |  | |.|||||  |..          .. ..||| | . . .|    |  .| |||||..|.    .  .|.|..| ...||   .
YQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPPYTDYVSTRWYRAPECLLRCTYYNSPMDIWAVGCIMYELYMLR

PLYAGNNE
||..|..|
PLFPGSSE

Kinase 81909.m00091.AA CLK 305-354 42 2.2e-13 35.8 In-house 209-258 (350) Show / Hide
Range on Protein: 305-354
Range on HMM: 209-258/350
Sequence Identity: 42% (21 aa)

QSRFYRAPEVILHISFTRAIDVWSFGLVIIELKLGHPLYAGNNEKEQLGM
..| ||||||||   .    ||||.| ...|| .|  |. .....| | |
STRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLFQTHDNREHLAM

Kinase 81909.m00091.AA STE 245-344 25 3.1e-13 43.21 In-house 152-269 (359) Show / Hide
Range on Protein: 245-344
Range on HMM: 152-269/359
Sequence Identity: 25% (32 aa)

LLKTVSKQICDS-LIFFHSLGLVHCDIKPENIVWTNDQKTTVNLIDFGCCC-------------------HEGNPLFKYMQSRFYRAPEVILH------I
..... .||.   | . ||.. .| |||| ||         | |.|||.|                      .        .  . |||||.        
QIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDK

SFTRAIDVWSFGLVIIELKLGHPLYA
  ..  |.||.|..|||.  |.| ..
GYDTKCDIWSLGCTIIEMATGKPPWH

Kinase 81909.m00091.AA CLK 403-430 53 5.5e-13 34.56 In-house 323-350 (350) Show / Hide
Range on Protein: 403-430
Range on HMM: 323-350/350
Sequence Identity: 53% (15 aa)

LVDLVRKCLEWDPNKRIKMTEVLKHPYL
| ||.||.|| ||.|||.  ..|.||. 
LFDLIRKMLEYDPSKRITCKDALQHPFF

Kinase 81909.m00091.AA RCK 401-430 46 7.4e-13 36.84 In-house 269-298 (298) Show / Hide
Range on Protein: 401-430
Range on HMM: 269-298/298
Sequence Identity: 46% (14 aa)

PDLVDLVRKCLEWDPNKRIKMTEVLKHPYL
.|...|..|.| |||.|||   ..|.||| 
QDCIELMEKMLQWDPQKRITAQQALQHPYF

Kinase 81909.m00091.AA DYRK2 400-430 38 1.3e-11 33.65 In-house 288-318 (318) Show / Hide
Range on Protein: 400-430
Range on HMM: 288-318/318
Sequence Identity: 38% (12 aa)

DPDLVDLVRKCLEWDPNKRIKMTEVLKHPYL
|....| ...|.|||| .|..  . ||||..
DENFIDFIKRCFEWDPSERMTPSQALKHPWI

Kinase 81909.m00091.AA STE 143-187 21 9.6e-09 27.13 In-house 1-78 (359) Show / Hide
Range on Protein: 143-187
Range on HMM: 1-78/359
Sequence Identity: 21% (17 aa)

YQQIVEICRGNFGSVLKCYDHK---------------TKKIVAVKLIK---DRP---------------KIHKQILME
.. | .| .|.||.| |...||               |..|.|.| ..   ...               ....|||.|
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKE

Kinase 81909.m00091.AA PRP4 405-430 57 1.2e-07 24.15 In-house 295-320 (320) Show / Hide
Range on Protein: 405-430
Range on HMM: 295-320/320
Sequence Identity: 57% (15 aa)

DLVRKCLEWDPNKRIKMTEVLKHPYL
||  |||  || ||| . |.||||..
DLLDKCLMLDPKKRITCNEALKHPFI

Kinase 81909.m00091.AA TyrKc 143-430 18 1.8e-07 -101.91 SMART 1-280 (280) Show / Hide
Range on Protein: 143-430
Range on HMM: 1-280/280
Sequence Identity: 18% (60 aa)

YQQIVEICRGNFGSVLKCYDHKTKKIVAVKLIKDRPKIHKQILMEKVALDMIQEADPKFTHF------IVPVIDKFYFR-------GFHCFCFELLWK--
 . . .. .|.|| | |.        |||| .|.               |...||    ...      ||  .             . ..  .|.  .  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----------REDFMREAR-IMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGD

-DTYTCQKDENFVGYEDGLLKTVSKQICDSLIFFHSLGLVHCDIKPENIVWTNDQKTTVNLIDFGCCCHEGNP-------LFKYM----QSR-----FYR
 . |   . ..        |   . ||..   . || ...| |.   |.  ....  ||   ||| .   ..          . .    ...        
LKDYLRKHRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM

APEVILHISFTRAIDVWSFGLVIIEL-KLGHPLYAG-------NNEKEQLGMYYSSLGPPDEKYLRSSPRFSEFFGDDASIKNEYSYPLFDELVVGLDPD
|||.| .  || . |||||| .. |.  .| . | |       | |  .. .    . .|.. |    |  |                 |    |.  ..
APECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY----P-MS-----------------F----VCCPDE

LVDLVRKCLEWDPNKRIKMTEVLKHPYL
. .. ..| . ||..|  ..|.  | ..
MYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase 81909.m00091.AA STE 401-430 43 3.9e-07 21.36 In-house 328-359 (359) Show / Hide
Range on Protein: 401-430
Range on HMM: 328-359/359
Sequence Identity: 43% (14 aa)

PDLVDLVRKCLEWDPNKRIKMTEVLK--HPYL
|.. | ..|||. ||||| . .. ||  || .
PEFKDFINKCLQKDPNKRPTASQLLKSEHPFI

Kinase 81909.m00091.AA DYRK1 405-430 34 1e-06 18.52 In-house 296-321 (321) Show / Hide
Range on Protein: 405-430
Range on HMM: 296-321/321
Sequence Identity: 34% (9 aa)

DLVRKCLEWDPNKRIKMTEVLKHPYL
||... |..||..||.  ..|.|...
DLIKRMLQYDPKQRITPYYALQHSFF

Kinase 81909.m00091.AA RCK 143-172 40 4e-06 14.95 In-house 1-30 (298) Show / Hide
Range on Protein: 143-172
Range on HMM: 1-30/298
Sequence Identity: 40% (12 aa)

YQQIVEICRGNFGSVLKCYDHKTKKIVAVK
|| | .. .| .|.|.|  . .|..||| |
YQIIKQLGDGTYGCVMKAQNKETGEIVAIK

Kinase 81909.m00091.AA HIPK 402-430 37 0.00011 10.14 In-house 301-329 (329) Show / Hide
Range on Protein: 402-430
Range on HMM: 301-329/329
Sequence Identity: 37% (11 aa)

DLVDLVRKCLEWDPNKRIKMTEVLKHPYL
. |.. .| . ||..|||   | |.||. 
EFVHVLKKMCTWDAHKRITPCEALNHPFV

Kinase 81909.m00091.AA PRP4 143-225 25 0.000588 10.47 In-house 1-86 (320) Show / Hide
Range on Protein: 143-225
Range on HMM: 1-86/320
Sequence Identity: 25% (22 aa)

YQQIVEICRGNFGSVLKCY-DHKTKKIVAVKLIKDRPKIHKQILMEKVALDMIQEA--DPKFTHFIVPVIDKFYFRGFHCFCFELL
|. .  .  | |. | .|    .... ||.| |  ..  ||  | |.  |  . .|  |.     .|   . |..|   |  || .
YRVYGYCGQGVFSNVCRCRDQTRGNEMVAIKIIRNNEIMHKTGLRELEILQKLNDAPTDKNDKFHCVRMFRHFNHRQHMCLVFECM

Kinase 81909.m00091.AA YAK 403-430 25 0.00127 7.74 In-house 320-347 (347) Show / Hide
Range on Protein: 403-430
Range on HMM: 320-347/347
Sequence Identity: 25% (7 aa)

LVDLVRKCLEWDPNKRIKMTEVLKHPYL
..|..   |. .|..| |     .||..
FIDFINQLLQLNPRERWKPMQAMQHPFI