Gene 93947.m00095 (T.vaginalis)
93947.m00095
Species: T.vaginalis
Alias: TvagK0668, 93947.m00095
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 93947.m00095.AA | Protein | None | 430 | None | Fasta, JSON |
| 93947.m00095.kin_dom | Protein Kinase Domain | None | 297 | None | Fasta, JSON |
Protein domains of 93947.m00095.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 93947.m00095.AA | DYRK | 127-423 | 42 | 2e-121 | 409.71 | In-house | 1-320 (320) | Show / Hide |
Range on Protein: 127-423 Range on HMM: 1-320/320 Sequence Identity: 42% (135 aa) YQQLEVLGKGSFGTVIKCLDHKTKELVAIKFLRDTKKVHDEILFENKIISRLQDGENSSTSGIIRYIESFSFREFFCIVMELLWKDTYTVLEARHFVGY- |. ||..|||||| |.|| ||||.|.|||| .| |. |. .. | ||...| . . .. .... ..| .|...||| ||| . | .| .|| |. YEILEYIGKGSFGQVVKCWDHKTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQDPDDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNHFQGFF SKNIIKMVAYQSAKALDFMHKH-NIVHCDIKPENIMFITE-QKKNIKIIDFGCSCFSGEIMFTYIQSRFYRAPEVVLGIEYDREIDIWSLGCVLCELVTG | | .. .|.| ..|.|.||. ||.|||.|||||| . .| .||.|||| ||| .. ..||||||||||||| ||. |. .||.|||||.| ||.|| SLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLKQPRNKSTIKVIDFGSSCFEHQRIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAELFTG RPLFDADTQIDLLAMIIETIGEPPKSMLDRG--SYTKKFFDG------------RN-------LKIQYNKDVRIPGPPKSRSLEAELNVSDAQFIDLILG ||| .. |.||.|.|..| ||| |.| | ....|||| .. .| ...|. .||..|....... | ||.|.|.. WPLFPGENEYDQLACIMEVLGMPPKWMIDKGRCRRKHKFFDCFMYCECDEWTKQNKITDHYMTPKCHPTKR-GQRRPPGRRNWDPRHQCDDHQFKDFIKK CLKWEPSERYTAEELMNHPFL ||.|.|..| |... ..||.. CLQWDPHKRITPSQALQHPWF |
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| Kinase | 93947.m00095.AA | DYRK2 | 127-423 | 39 | 4.5e-120 | 392.27 | In-house | 1-318 (318) | Show / Hide |
Range on Protein: 127-423 Range on HMM: 1-318/318 Sequence Identity: 39% (125 aa) YQQLEVLGKGSFGTVIKCLDHKTKELVAIKFLRDTKKVHDEILFENKIISRLQDGENSSTSGIIRYIESFSFREFFCIVMELLWKDTYTVLEARHFVGYS | |||.|||||| |.||.|||||..|||| .| |. | .. | .|.... .|. ... ..| || ..||. ||| . | . .|| |.| YEILEVIGKGSFGQVVKCYDHKTKQHVAIKMIRNKKRFHNQAYEEIRILHHIRRQDKDNTMNCVHMLDYFYFRNHHCITFELLSMNLYEYIKKNHFQGFS KNIIKMVAYQSAKALDFMHKHNIVHCDIKPENIMFITEQKKNIKIIDFGCSCFSGE-IMFTYIQSRFYRAPEVVLGIEYDREIDIWSLGCVLCELVTGRP ... |.. ..|.| ||.||.||| |||||. . . .||.|||| ||| . ..||||||||||||| ||. |. .||.||.||.. ||.|| | LQLVRRFAHSILQCLRFLHKNNIIHCDLKPENILLKQWNRSGIKVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYTGYP LFDADTQIDLLAMIIETIGEPPKSMLDRG-----SYTKKFFD--------------GRNLKIQYNKDVRIPGPPKSRSLEAELN-VSDAQFIDLILGCLK || . | .|...| .| |||...| ...| ||. .. .. .|.. .|| |.|. . | | ||| |. |.. LFPGENENDQFACMMEVLGMPPKKFFDTWFYIHCFRRKYFFNSHCFEWYCTFMTDHSMEIPKHYKNRHGKRRPPGSKSWKSVLKGCEDENFIDFIKRCFE WEPSERYTAEELMNHPFL |.|||| |... .||.. WDPSERMTPSQALKHPWI |
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| Kinase | 93947.m00095.AA | CMGC | 127-423 | 18 | 4.7e-93 | 306.08 | In-house | 1-513 (513) | Show / Hide |
Range on Protein: 127-423
Range on HMM: 1-513/513
Sequence Identity: 18% (96 aa)
YQQLEVLGKGSFGTVIKCLD--------------HKTKELVAIKFLRDTKKVHDE-------------ILFENKIISRLQDGENSST----------SG-
|. ....|.|..|.| || | |.|.|.|||| .. . ... .| | || .|.. ..
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDP-NWQRRDDPDNKHHN
-IIRYIESFSFRE-----------------FFCIVMELLWKDTYTVLEARHF-------VGYSKNI------------IKMVA------YQSAKALD--F
|.. ...| ... ...|.|.. .| | ... .| .. | || || ..|. .
NIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKY
MHKHN--IVHCDIKPENIMFITE------------------QKKNIKIIDFGCSCFSGE------------------------IMFTYIQSRFYRAPEVV
.|.|. |.|.|.|||||.. . .. ..||.||| ... .. . .|...|.|||||.
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEIL
LGIE----------YDREIDIWSLGCVLCELVTG--------RPLFDADTQ-----------IDLLAMIIETIGEPPKSMLDRGS-------YTKKFFD-
|| . |. .||.||.||.. |..|| .||| .. || |..|....| |. .|...| .......
LGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGKRHFNFCKHEEEWPNM
------------------------GRNLKIQYNKDVRIPGPPKSRSLEAELNV--------------------------------SDAQFIDLILGCLKW
. ..|| |.. . |.. ..|. .. | |.|||. ..|..
IKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQY
EPSERYTAEELMNHPFL
.|..| |||. ..||..
DPDKRITAEQALQHPYF
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| Kinase | 93947.m00095.AA | S_TKc | 127-423 | 24 | 4.8e-81 | 276.48 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 127-423 Range on HMM: 1-231/231 Sequence Identity: 24% (77 aa) YQQLEVLGKGSFGTVIKCLDHKTKELVAIKFLRDTKKVHDEILFENKIISRLQDGENSSTSGIIRYIESFSFREFFCIVMELLWK---DTYTVLEARHFV |. |...|||.||.| || ..||...|||| .. . |. | .| .. |......| .....|||.. | ..... | YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH G----YSKNIIKMVAYQSAKALDFMHKHNIVHCDIKPENIMFITEQKKNIKIIDFGCSCFSGEIMFTYIQSRFYRAPEVVLGIEYDR-EIDIWSLGCVLC | .. .. ..|| ..||...|.|.|.|.|.|||||.. . .|||.||| ... |.. ...|.||||. |.. ..|.||.||.| GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY ELVTGRPLFDADTQIDLLAMIIETIGEPPKSMLDRGSYTKKFFDGRNLKIQYNKDVRIPGPPKSRSLEAELNVSDAQFIDLILGCLKWEPSERYTAEELM |...|.|.|. |.... .| . ...|.| .||...|..|.|| |.. EMLCGYPPFP---QMQMMFKKIG---------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EAL N-------HPFL . ||.. QDEWDIKCHPWF |
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| Kinase | 93947.m00095.AA | DYRK1 | 127-372 | 41 | 1.9e-75 | 256.99 | In-house | 1-248 (321) | Show / Hide |
Range on Protein: 127-372 Range on HMM: 1-248/321 Sequence Identity: 41% (103 aa) YQQLEVLGKGSFGTVIKCLDHKTKELVAIKFLRDTKKVHDEILFENKIISRLQDGENSSTSGIIRYIESFSFREFFCIVMELLWKDTYTVLEARHFVGYS |. .|||||| |.| ||...|.|||| .. | . . | ... . .. . |.. . | ||. |.|.||| | .| || | | YEIDSLIGKGSFGQVVKAYDHQEQEYVAIKIIKNKKPFYNQAQIEIRLLELMNKHDKEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVS KNIIKMVAYQSAKALDFMH--KHNIVHCDIKPENIMFITEQKKNIKIIDFGCSCFSGEIMFTYIQSRFYRAPEVVLGIEYDREIDIWSLGCVLCELVTGR |... | | ..|| || .|.|||.|||||. . .. ||||||| || .|. .. ||||||||.|||.|||||| .||.|||||.| |. || LNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENILLCNPKRSAIKIIDFGSSCQLGQRIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMHTGE PLFDADTQIDLLAMIIETIGEPPKSMLDRGSYTKKFFDGRNLKIQYNK ||| .| . |.| .| ||| |.|.. ..|.|. . .. | | PLFSGSNEVDQMNKIVEVLGMPPKHMIDQAPKAHKYFEKDPDNTWYCK |
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| Kinase | 93947.m00095.AA | Pkinase | 127-423 | 25 | 1e-70 | 246.07 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 127-423 Range on HMM: 1-293/293 Sequence Identity: 25% (84 aa) YQQLEVLGKGSFGTVIKCLDHKTKELVAIKFLRDTKKVHDE---ILF--ENKIISRLQDGENSSTSGIIRYIESFSFREFFCIVMELLWK-----DTYTV |. ....|.||||.| || ...| ..||.| .. .. ... . | .| || . .| |.|....| . ..|||.. . | ... YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPN-----IVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDY LE---ARHFVGYSKNIIKMVAYQSAKALDFMHKHNIVHCDIKPENIMFITEQKKN---IKIIDFGCSCF---SGEIMFTYIQSRFYRAPEVVL-GIEYDR .. . | | . .|...|| ...|...|...|.|.|.|||||.. .. . .||.|||.... ... | |. ...|.||||.. | .|.. ISTWRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDYNNS-MTTFCGTPWYMAPEVIRGGQYYGP EIDIWSLGCVLCELVTGRPLFDAD----TQIDLLAMIIETIGEPPKSM---LDRGSYTKKFFDGRNLKIQYNKDVRIPGPPKSRSLEAELNVSDAQFIDL ..|.||.||.| |...|||.|. . . .| ..|| .. | |... ....|| . |.. . . .. . ..|. KVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H----------------F-HWTF-HNWSEECKDF ILGCLKWEPSERYTAEELMNHPFL | .||.. |..|.|||....||.. IKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | 93947.m00095.AA | HIPK | 127-362 | 34 | 1.1e-63 | 199.2 | In-house | 1-238 (329) | Show / Hide |
Range on Protein: 127-362 Range on HMM: 1-238/329 Sequence Identity: 34% (83 aa) YQQLEVLGKGSFGTVIKCLDHKTKELVAIKFLRDTKKVHDEILFENKIISRLQDGENSSTSGIIRYIESFSFREFFCIVMELLWKDTYTVLEARHFVGYS | ||.||.| || |.|| . |.|.|||| |.. . | .|...|. .||. ..| | | .. .|.| |.| | . .| YEVLEFLGRGTFGQVVKCWKRGTNEMVAIKILKNHPYYARQGQIEVSILHCLS-QENADEYHFVRAYECFHHKNHTCLVFEMLEQNLYDFQKQNKFMPLP KNIIKMVAYQSAKALDFMHKHNIVHCDIKPENIMFITEQKK--NIKIIDFG-CSCFSGEIMFTYIQSRFYRAPEVVLGIEYDREIDIWSLGCVLCELVTG . |. . | ..|| . . ..| |.|||||| . ... .|.|||| | .| . ||.|||.|||||..||. . ..|.||||||. || | LKHIRPILQQVLTALMKLKELGLIHADLKPENIMLVDPTRCPYRVKVIDFGSASHVSKVVCNTYLQSRYYRAPEIILGLPFCENHDMWSLGCVIAELFLG RPLFDADTQIDLLAMIIETIGEPPKSMLDRGSYTKKFFD .||.. |. |..| . | ...| .. ...||| WPLYPGADEYDQIRYICQTQHLPHEHLLHAACKKHRFFD |
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| Kinase | 93947.m00095.AA | YAK | 127-361 | 35 | 4.6e-55 | 185.36 | In-house | 1-239 (347) | Show / Hide |
Range on Protein: 127-361 Range on HMM: 1-239/347 Sequence Identity: 35% (85 aa) YQQLEVLGKGSFGTVIKCLDHKTKELVAIKFLRDTKKVHDEILFENKIISRLQDGENSSTSG----IIRYIESFSFREFFCIVMELLWKDTYTVLEARHF | | .||.| || |.|| |.||.|.| . | .| | . . |.| . .| .. ||.| |.| | | | YIVLDMLGQGTFGQVVKCQNCDTNELFAVKVIKNRQAYFQQAKNEIQILRVLNQQHDPNNKNYQKHILRMYDFFVHKNHFCLVFEMLSNNLYEYLKQNKF VGYSKNIIKMVAYQSAKALDFMHKHNIVHCDIKPENIMFITEQKKNIKIIDFGCSCFSGEIMFTYIQSRFYRAPEVVLGIEYDREIDIWSLGCVLCELVT | | ..|. | .. .|.||| |||||| | ||||||| || . ||||.|.||.||..... | || |||||.. || CGFSFQLIRQWTKQILDGMCVLENKQIIHCDLKPENIMLCKPNKPEIKIIDFGSSCQEKKMVYTYIQQRHYRSPEIIVWMIYCTSIDMWSLGCIVAELFL GRPLFDADTQIDLLAMIIETIGEPPKSMLDRGSYTKKFF | |.| . . ||.. | || |.|.| . |.| GLPIFPGNSEYNQIKRIIDMLGYPPSWMIDQGRFKNKYF |
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| Kinase | 93947.m00095.AA | DyrkP | 127-366 | 36 | 1.4e-51 | 167.76 | In-house | 1-244 (323) | Show / Hide |
Range on Protein: 127-366 Range on HMM: 1-244/323 Sequence Identity: 36% (88 aa) YQQLEVLGKGSFGTVIKCLDHKTKELVAIKFLRDTKKVHDEILFENKIISRLQDGENSSTSGIIRYIESFSFREFFCIVMELLWKDTYTVL----EARHF || .| || | |.|.| .| .. .| . | | . | |.. . ..|| . | .| |. ||| | | YQIMEYLGSAAFSKAIQCQDKQTNQMMCMKIIENNKDYFDQSIDEIKLLRYINYNGDVDEKNVLRYYDYFYHKEHLFIITELLKDNLYEFYKFNRENEQQ VGYSKNIIKMVAYQSAKALDFMHKHNIVHCDIKPENIMFITEQKKNIKIIDFGCSCFSGEIMFTYIQSRFYRAPEVVLGIEYDREIDIWSLGCVLCELVT . .. . | |||..| ..|||.|||||. | ..|||||| ||| . . |.||| ||||||..| || ||.|||||.| || | RYFTVGRLQKITQQILIALDYIHSLRLIHCDLKPENILMKSYPKCQVKIIDFGSSCFIHDHLSSYVQSRSYRAPEVIIGCKYDYRIDMWSLGCILAELWT GRPLFDADTQIDLLAMIIETIGEPPKSMLDRGSYTKKFFDGRNL | || |. ||| .| || | |. | . || . | GNVLFQNDNIQGLLARVIGIIGPFPEWMMQEGRLVQNFFTRKRL |
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| Kinase | 93947.m00095.AA | CDKL | 224-423 | 34 | 1.5e-43 | 146.75 | In-house | 94-286 (286) | Show / Hide |
Range on Protein: 224-423 Range on HMM: 94-286/286 Sequence Identity: 34% (70 aa) GYSKNIIKMVAYQSAKALDFMHKHNIVHCDIKPENIMFITEQKKNIKIIDFG---CSCFSGEIMFTYIQSRFYRAPEVVLG-IEYDREIDIWSLGCVLCE | .. .. . .| ||..| ||||..| ||||||| .|| ... .|. ||| .||| | | ||||| ..| .| ..|||..|||. | GVDEHVVRKYMWQILKAINFCHKHNCIHRDIKPENI-LITPKNGQVKLCDFGFARMLAKPGEIYTDYVATRWYRAPELLVGDTQYGKPVDIWAIGCVMAE LVTGRPLFDADTQIDLLAMIIETIGEPPKSMLDRGSYTKKFFDGRNLKIQYNKDVRIPGPPKSRSLEAE-LNVSDAQFIDLILGCLKWEPSERYTAEELM ...| ||. . ||.| .|. ..|. ...| .. | .| .. .....| ... .|| .|.|.. .|.. .||. |.||.|.|.|| MIDGQPLWPGQSDIDQLYHIQKCLGP----LIPR---HQEIF----SKNPFFHGMKFPEIEHMEPLEKRYPNKSNKKALDFMKKCLHMDPDERMTCEQLM NHPFL .||. HHPYF |
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| Kinase | 93947.m00095.AA | CAMK | 240-423 | 22 | 4e-43 | 136.36 | In-house | 191-425 (425) | Show / Hide |
Range on Protein: 240-423
Range on HMM: 191-425/425
Sequence Identity: 22% (59 aa)
ALDFMHKHNIVHCDIKPENIMFITEQK---------------KNIKIIDFGCS--CFS------------------------GEIMFTYIQSRFYRA-PE
|....|.|||||.|.|||||.. . . |||||||| . ... |. | |. . | | ||
AVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPE
VVLG-------------IEYD-REIDIWSLGCVLCELVTGRPLFDAD-------------TQIDLLAMIIETIGEPPKSMLDRGS--YTKKFFDGRNLKI
|..| ..|. ...|.||.|..| ...|.| |..| .. .|. .|.. . | .... | |
VLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNY------------
QYNKDVRIPGPPKSRSLEAELNVSDA-------QFIDLILGCLKWEPSERYTAEELMNHPFL
. | ..|| . .||| ..|. .|..|.|.|. .|||..
---------------GPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | 93947.m00095.AA | CLK | 127-261 | 28 | 9e-32 | 91.97 | In-house | 1-147 (350) | Show / Hide |
Range on Protein: 127-261 Range on HMM: 1-147/350 Sequence Identity: 28% (42 aa) YQQLEVLGKGSFGTVIKCLDHKT-KELVAIKFLRDTKKVHDEILFENK-IISRLQDG-ENSSTSG--IIRYIESFSF-REFFCIVMELLWKDTYTVLEAR | . .|| | ||.| .| ||| | .||.|. | .|. .. | . |. .. . ... ... ...| . .|||.||. . .| .. . YEIVCTLGEGTFGKVVECWDHKNGKKYVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFDYGHGHICIVFELYGLSIYDFMKSN H------FVGYSKNIIKMVAYQSAKALDFMHKHNIVHCDIKPENIMF . . .| . |. ||| .|. |.|. ..| | ||||| | NSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHDMKLTHTDLKPENICF |
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| Kinase | 93947.m00095.AA | CLK | 268-423 | 31 | 4.1e-28 | 80.78 | In-house | 185-350 (350) | Show / Hide |
Range on Protein: 268-423 Range on HMM: 185-350/350 Sequence Identity: 31% (53 aa) NIKIIDFGCSC---FSGEIMFTYIQSRFYRAPEVVLGIEYDREIDIWSLGCVLCELVTGRPLFDADTQIDLLAMIIETIG-EPPKSMLDRGS---YTKKF .|..|||| | | | ...| ||||||.|| . |.|| ||.| ||.|| ||. .. |||. . | |..| | ..|. HICVIDFGSATKIRFDHEHHSTIVSTRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLFQTHDNREHLAMMERIMGMPIPQWMIQRTRRFKVKQKY F-----DGRNLKIQYNKDVRIPGPPKSRSLEAELNVSDAQFIDLILGCLKWEPSERYTAEELMNHPFL | |... . . |. . | ... |..||| .| .|| | |. . ||| FYHNRLDWDW-HNSDGRYVMENCKP-LKQYMDCKDPEHRQLFDLIRKMLEYDPSKRITCKDALQHPFF |
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| Kinase | 93947.m00095.AA | CAMK | 132-208 | 19 | 5.8e-11 | 30.83 | In-house | 1-141 (425) | Show / Hide |
Range on Protein: 132-208 Range on HMM: 1-141/425 Sequence Identity: 19% (27 aa) VLGKGSFGTVIKCLDHKTK------------ELVAIKF-------------------LRDTKKVH----------DEILFENKIISRLQDGEN-SSTSGI .||.||||.| .| . .|. . ||||. ....|. | .... | .| ..||...| . | TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI IRYIESFS-----------------FRE---FFCIVM---EL |. .| . | . ....|| |. IKLYEVYEDPHYFKNTNDYETSKQVF-TKDKHMYMVMEIMEY |
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| Kinase | 93947.m00095.AA | TyrKc | 127-423 | 17 | 2.8e-10 | -56.57 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 127-423 Range on HMM: 1-280/280 Sequence Identity: 17% (57 aa) YQQLEVLGKGSFGTVIKCLDHKTKELVAIKFLRDTKKVHDEILFENKIISRL-QDGENSSTSGIIRYIESFSFR-------EFFCIVMELL-WKDTYTVL . ...|| | ||.| |. . ||.| |.. . . ... | .| ..| . .| |.| . . | .||||. . | | ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPN-----IVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL -EARHFVGYSKNIIKMVAYQSAKALDFMHKHNIVHCDIKPENIMFITEQKKNIKIIDFGCSCFSGEI-MF-----TYI-----QSR-----FYRAPEVVL . |. . ..| |. .. |..|..| |. |.. ..|.. .|| ||| | . .. . .| ... |||. RKHRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCL-VGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN GIEYDREIDIWSLGCVLCELVT-GRPLFDA-----DTQIDLLAMIIETIGEPPKSM----LDRGSYTKKFFDGRNLKIQYNKDVRIPGPPKSRSLEAELN .. . |.|| | .. |. | | . . ..... . . |. . YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS--------------------------------F-----V VSDAQFIDLILGCLKWEPSERYTAEELMNHPFL . .... | . .|..| | .|. | .. CCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
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| Kinase | 93947.m00095.AA | CDKL | 127-156 | 46 | 4.3e-09 | 27.24 | In-house | 1-30 (286) | Show / Hide |
Range on Protein: 127-156 Range on HMM: 1-30/286 Sequence Identity: 46% (14 aa) YQQLEVLGKGSFGTVIKCLDHKTKELVAIK | .| ..| || |.| || . | ..|||| YEKLGKVGEGSYGVVMKCRNKETGQIVAIK |
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| Kinase | 93947.m00095.AA | YAK | 396-423 | 42 | 2.8e-07 | 20.38 | In-house | 320-347 (347) | Show / Hide |
Range on Protein: 396-423 Range on HMM: 320-347/347 Sequence Identity: 42% (12 aa) FIDLILGCLKWEPSERYTAEELMNHPFL |||.| . | .| || .. | |||. FIDFINQLLQLNPRERWKPMQAMQHPFI |
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| Kinase | 93947.m00095.AA | DyrkP | 380-423 | 38 | 5.9e-07 | 18.2 | In-house | 280-323 (323) | Show / Hide |
Range on Protein: 380-423 Range on HMM: 280-323/323 Sequence Identity: 38% (17 aa) PKSRSLEAELNVSDAQFIDLILGCLKWEPSERYTAEELMNHPFL || | | | | ||| . ||. . | || | ..||.. PKHSNLRARLRTDDHMFIDFVRQCLQIDFTRRPTAKEALQHPWF |
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| Kinase | 93947.m00095.AA | DYRK1 | 374-423 | 33 | 4.2e-05 | 13.31 | In-house | 271-321 (321) | Show / Hide |
Range on Protein: 374-423 Range on HMM: 271-321/321 Sequence Identity: 33% (17 aa) VRIPGPPKSRSLEAELNVSD-AQFIDLILGCLKWEPSERYTAEELMNHPFL |. || | |. |.| .| |||. |...| .| | . . |.|. VETGGPGGRRKGEPGHSVEDYLKFKDLIKRMLQYDPKQRITPYYALQHSFF |
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| Kinase | 93947.m00095.AA | Pkinase_Tyr | 127-161 | 33 | 0.000281 | 15.11 | Pfam | 1-39 (270) | Show / Hide |
Range on Protein: 127-161 Range on HMM: 1-39/270 Sequence Identity: 33% (13 aa) YQQLEVLGKGSFGTVIKCLDH----KTKELVAIKFLRDT . ...||.|.||.| |. . .|| ||.| |... ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEG |
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| Kinase | 93947.m00095.AA | HIPK | 395-423 | 31 | 0.000721 | 7.52 | In-house | 301-329 (329) | Show / Hide |
Range on Protein: 395-423 Range on HMM: 301-329/329 Sequence Identity: 31% (9 aa) QFIDLILGCLKWEPSERYTAEELMNHPFL .|... . |.. .|.| | .|||| EFVHVLKKMCTWDAHKRITPCEALNHPFV |
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| Kinase | 93947.m00095.AA | Pkinase_Tyr | 234-254 | 28 | 1.002566 | 3.08 | Pfam | 117-137 (270) | Show / Hide |
Range on Protein: 234-254 Range on HMM: 117-137/270 Sequence Identity: 28% (6 aa) AYQSAKALDFMHKHNIVHCDI ..| ||.... . .|..| |. CWQIAKGMEYLESKNCIHRDL |
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