Gene 94179.m00238 (T.vaginalis)

94179.m00238

Species: T.vaginalis
Alias: TvagK0112, 94179.m00238
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag2

Sequence

Name Sequence Type Origin Length Description Download
94179.m00238.AA Protein None 364 None Fasta, JSON
94179.m00238.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of 94179.m00238.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 94179.m00238.AA CAMK 24-271 24 5.1e-118 382.05 In-house 1-425 (425) Show / Hide 
Range on Protein: 24-271
Range on HMM: 1-425/425
Sequence Identity: 24% (104 aa)

PIGKGSFSVVKIVEDSVSG------------QLFAAKIIPKNKLV-------------------------ASNLSERFETEIRIIRQ-------LNHPGI
 .|.|||..|| ...  ..            | .|.|||.|.||                            .  .... ||.| ..       |.|| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQLYDLFKD-------------------ENNYYIIM---ELCSNGEL----YEQIIEN---------------ERLSEIEAKYYMKQILEALCYVHNLGI
..||. . |                   ....|..|   |.||.|||    .. |.|.                |..| ||..|..||..|. | |...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

CHRDIKPENILLDEQ-----------------GHAKISDFGLSRFVTAVG------------------------LAETPCGSPCYAS-PECIRG------
.|||.||||||||.                  .  ||.|||......                           . .|.||.|.|.. || ..|      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------GSYDGRKSDMWSCGVLCFAMLTGQLPWTKR-------------NQSQLFDQIQKADYS-IPSY---------------VSEL--------GKR
         |.|.|.|||||||....||.| .|.                |...|| .|.|..|. .|.|               .|.          | 
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

FIRGLMDPNPETRLNVEQALSHPWL
.||... ..|| |...||.|.|||.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 94179.m00238.AA CAMKL 19-271 36 8.9e-108 345.05 In-house 1-297 (297) Show / Hide 
Range on Protein: 19-271
Range on HMM: 1-297/297
Sequence Identity: 36% (108 aa)

YRFMGPIGKGSFSVVKIVED-SVSGQLFAAKIIPKNKLVASNLSERF------------ETEIRIIRQLN---HPGIVQLYDLFKDENN------YYIIM
||.   .|||||..||  .. .  |.  | ||| |.|.     ...             . ||.| ..||   || |..||. . ....      .|..|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELCSNGE--LYEQIIEN----ERLSEIEAKYYMKQILEALCYVHNLGICHRDIKPENILLDEQG--HAKISDFGLSRFVTA-----VGLAETPCGSPCYA
|.||.||  |.. |...    .|..| ||. | .||..|. | |..||.|||||||||||||.|   .||.|||.| . .        . .| ||||.|.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

SPECIRG--GSYDGRKSDMWSCGVLCFAMLTGQLPWTKR--------NQSQLFDQIQKADYSIP--SYVSELGKRFIRGLMDPNPETRLNVEQALSHPWL
.|| . |   .|||.| |.|||||. .||..|.||.           |.  |. .| .  | .|  ..||   ...||... .||| | ...| ..|||.
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
S_TKc 94179.m00238.AA S_TKc 19-271 36 8.20000000001e-107 362.07 SMART 1-231 (231) Show / Hide 
Range on Protein: 19-271
Range on HMM: 1-231/231
Sequence Identity: 36% (98 aa)

YRFMGPIGKGSFSVVKIVEDSVSGQLFAAKIIPKNKLVASNLSERFETEIRIIRQLNHPGIVQLYDLFKDENNYYIIMELCSN--GELYEQIIENER---
|... .||||.|..|. . .  .|...| |||.          |... ||.| .. .|| ||.||| | | ...|..||.|..  |.|.. | .. |   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LSEIEAKYYMKQILEALCYVHNLGICHRDIKPENILLDEQGHAKISDFGLSRFVTAVGLAETPCGSPCYASPECIRGGSYDGRKSDMWSCGVLCFAM
   ..| .|..||.||..|| | |..||.|||.|||||||||  | ||.||||.|..       | ||.| | .|| .   .|...|.|.||||.. . |
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LTGQLPWTKRNQSQLFDQIQKADYSIPSYVSELGKRFIRGLMDPNPETRLNVEQALS-------HPWL
|.|. |.   .. ..|..|           |. .| |||.... .|| |. . .||        |||.
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 94179.m00238.AA AMPK 19-271 38 1.3e-103 308.47 In-house 1-254 (254) Show / Hide 
Range on Protein: 19-271
Range on HMM: 1-254/254
Sequence Identity: 38% (98 aa)

YRFMGPIGKGSFSVVKIVEDSVSGQLFAAKIIPKNKLVASNLSERFETEIRIIRQLNHPGIVQLYDLF-KDENNYYIIMELCSNGELYEQIIENERLSEI
|     ||.|.|  ||. .    |.  | ||. | |.  .  .|| . ||.| . ..|| |.|||.   . .   ...||  |.|||.. |. ..||.| 
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EAKYYMKQILEALCYVHNLGICHRDIKPENILLDEQGHAKISDFGLSRFVTAVGLAETPCGSPCYASPECIRGGSYDGRKSDMWSCGVLCFAMLTGQLPW
||. ...||. .. |.|...| ||| ||||.|||.. . || |||||   .   .  | |||||||.|| | |  | |.. | |||||  .||| | || 
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

TKRNQSQLFDQIQKADYSIPSYVSELGKRFIRGLMDPNPETRLNVEQALSHPWL
   |...|.. | . .|.||...|.  |  |...  ..|. |.....   |||.
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 94179.m00238.AA AGC 19-271 23 3.2e-99 256.55 In-house 1-395 (395) Show / Hide 
Range on Protein: 19-271
Range on HMM: 1-395/395
Sequence Identity: 23% (95 aa)

YRFMGPIGKGSFSVVKIVEDS------VSGQLFAAKIIPKNK--------LVASNLSER-------FETEIRIIRQLN----------HPGIVQ-LYDLF
..|  .||||||. |  |..        .|...| |.. | .         |. ...|        .  | .|  ..|          || ||. |.  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

KDENN--YYIIMELCS---------NG-ELYEQII---ENERLSEIEAKYYMKQ-------ILEALCYVHN-LGICHRD-IKPENILLDEQGHAKISDFG
.|...   |..||...          | ||. ..     . |..| .|..|. .       |. || | |. .|| ||| .|||||||||.|| |..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSRFVTA---------------------------------------------------VGLAETPCG--SPCYASPECIRGGSYDGRKSDMWS--CGVLC
|.  .                                                       .. | ||  .| | .|| .      |.  | ||   |.| 
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCLM

FAMLTGQLPWTKRN----------QSQLFDQIQ------KADYSIP----------SYVSELGKRFIRGLMDPNPETRLN----------VEQALSHPWL
. ||||. | .  |          . ..|..|.      . .  .|          ...|.  | .|..|. ..|| ||           .|.  .||| 
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 94179.m00238.AA MARK 19-271 37 1.1e-97 319.8 In-house 1-262 (262) Show / Hide 
Range on Protein: 19-271
Range on HMM: 1-262/262
Sequence Identity: 37% (99 aa)

YRFMGPIGKGSFSVVKIVEDSVSGQLFAAKIIPKNKLVASNLSERFETEIRIIRQLNHPGIVQLYDLFK--DENN-YYIIMELCSNGELYEQIIEN--ER
|..   ||.||...|| . .  .|. .| ||..|.||   .  . .. ||.| ..|.|| |..|.. .   .|..  |.|||..|.||||. |..    |
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LSEIEAKYYMKQILEALCYVHNLGICHRDIKPENILLDEQG--HAKISDFGLSRFVTAVGLAETPCGSPCYASPECIRGGSYDGRKSDMWSCGVLCFAML
|.| ||. . .||..|..| |. .|.||||||||||.||.|   .||.|||.|. ..   . .| ||.| |..|| . .  |||.| |.||.||. ..|.
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

TGQLPWTKRN--QSQLFDQIQKADYSIPSYVSELGKRFIRGLMDPNPETRLNVEQALSHPWL
.|..|.   .  . .|. .|.. .|.||..||   . .|. |. .||| |  .|. ..|||.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 94179.m00238.AA Pkinase 19-271 35 5.1e-95 326.76 Pfam 1-293 (293) Show / Hide 
Range on Protein: 19-271
Range on HMM: 1-293/293
Sequence Identity: 35% (105 aa)

YRFMGPIGKGSFSVVKIVEDSVSGQLFAAKIIPKNKLVASNLSERFE-TEIRIIRQLNHPGIVQLYDLFKDENNYYIIMELCSNG----ELYEQII--EN
|.. ..||.|||..|..  .  .|...| |||.| .   . . ...  .||.| . |||| ||.||| | |....|..||.| .|    .|.. |   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

ERL--SEIEAKYYMKQILEALCYVHNLGICHRDIKPENILLDEQGHA----KISDFGLSRF--VTAVGLAETPCGSPCYASPECIRGGSYDGRKSDMWSC
 ..  || |.| ||.|||..| | |. ||.|||.||||||.|..||     ||.||||...      . . |.||.| |..|| ||||.|.|.|.|||||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVLCFAMLTGQLPWTKR------NQSQLFDQIQKADYSIPSYVS---------------------ELGKRFIRGLMDPNPETRLNVEQALSHPWL
|.... ||.|..|.  .      .| |....| ..... ... .                     | .| ||... ...|. |.. ||.| |||.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 94179.m00238.AA CAMK1 19-271 35 4.4e-93 270.94 In-house 1-276 (276) Show / Hide 
Range on Protein: 19-271
Range on HMM: 1-276/276
Sequence Identity: 35% (98 aa)

YRFMGPIGKGSFSVVKIVEDSVS---GQLFAAKIIP-KNKLVASNLS--ERFETEIRIIR---QLNHPGIVQLYDLFKDENNYYIIMELCSNGELYEQII
| |.  ||.|.||.|. ...  .   |. .| |.|  |  .  .. .  |..|.|| | .   ...|| |...|. . ..| .|..|||...||| ..|.
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

ENERLSEIEAKYYMKQILEALCYVHNLGICHRDIKPENILLDEQ-GHA--K--ISDFGLSRFVT-AVGLAETPCGSPCYASPECIRG---GSYDGRKSDM
|..  .| .|   |||||.|. | | .||.|||.||||.|.  .  ..  |  |.|||||...   ..| .|.||.| |  || . .     ||  . ||
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYD-KACDM

WSCGVLCFAMLTGQLPWTKRN-QSQLFDQIQKADYSIPSY----VSEL-GKRFIRGLMDPNPETRLNVEQALSHPWL
||.||  . .|.|  |    | ...||..| |..|  ||     .|.   | ||.......|. |...||.| |||.
WSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase 94179.m00238.AA RSK 19-271 32 1.1e-86 294.27 In-house 1-278 (278) Show / Hide 
Range on Protein: 19-271
Range on HMM: 1-278/278
Sequence Identity: 32% (90 aa)

YRFMGPIGKGSFSVVKIVEDSVSGQLFAAKIIPKNKLVASNL-SERFETEIRIIRQLN-HPGIVQLYDLFKDENNYYIIMELCSNGELYEQIIENER---
 .  |..|.|...... .... .||..| |.. |.|.|...   ..  ||..|    . || ||.|.. |..|   |.|||.|. |||.. . . ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LSEIEAKYYMKQILEALCYVHNLGICHRDIKPENILLDE---QGHAKISDFGLSRF-VTA-VGLAETPCGSPCYASPECIR----GGSYDGRKSDMWSCG
.|| ||..|| .|  |. . | .|| |||.||||||.|.   .|| |..|||...  .    ... |.|..  |. || ..    .| .| .  | || |
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHD-KACDWWSLG

VLCFAMLTGQLPWTK---RNQSQLFDQIQKAD--YSIP--SYVSELGKRFIRGLMDPNPETRLN-----VEQALSHPWL
|| . ||||..| .     |.......|||..   ..|  .|.|.  | .||...  .|. ||.     .|. ..|||.
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 94179.m00238.AA RAD53 19-271 32 2.5e-86 257.1 In-house 1-305 (305) Show / Hide 
Range on Protein: 19-271
Range on HMM: 1-305/305
Sequence Identity: 32% (98 aa)

YRFMGPIGKGSFSVVKIVEDSVSGQLFAAKIIPKNK-----LVASNLSERFETEIRIIRQLNHPGIVQLYDLFKD-ENNYYIIMELCSNGELYEQIIENE
| . . .|.| |..|| . .   .| .| ||| |.|       ...  .....|..| . |||| |...|| | . . .||...|| ..|||.. |. |.
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

R----LSEIEAKYYMKQILEALCYVHNLGICHRDIKPENILLDEQGHA------------------KISDFGLSRFVTAVGLAETPCGSPCYASPECIRG
|    ..| ..||| .|...|. | |..||||||.||||||...|..                   ||.|||||.||    .. | ||.| |  || |..
RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVITS

------GSYD--------GRKSDMWSCGVLCFAMLTGQLPWT-KRNQ----SQLFDQIQK-ADYSI----PSYVSELGKRFIRGLMDPNPETRLNVEQAL
      ...         ..| |.|| |.. . .|.| .|    . |     |||.|| . . |.      . .||  | .|...   .|| |.....||
KGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEAL

SHPWL
.|||.
NHPWM
Kinase 94179.m00238.AA Ciliate-E2 19-271 27 5.2e-86 292.05 In-house 1-365 (365) Show / Hide 
Range on Protein: 19-271
Range on HMM: 1-365/365
Sequence Identity: 27% (104 aa)

YRFMGPIGKGSFSVVKIVEDSVSGQLFAAKIIPKNKLVAS-------------------NLSERFETEIRIIR----------------QLNHPGIVQLY
| |   ||.|.|..|. ...   ...|| |||  .|.  .                   |  | .. ||.|.|                ||||| |...|
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQ-QRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMY

DLFK--DENNYYIIMELCSNGELYEQIIEN-----------ERLSEIEAKYYMKQILE---------------ALCYVHNLG-ICHRDIKPENILLDEQG
. |.  |.||.|..||.|. |.|.. |..|           ....| |.||.|||||.               || | |. . |.||||||||||.    
ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

HAKISDFGLSRFVTAV--------------------------------GLAETPCGSPCYASPECIRGGSYDG--------RKSDMWSCGVLCFAMLTGQ
  ||.|||||....                                   .. | ||.| | .|| ..|..||.         |.|.||.||. . ||.|.
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

LPWTKRNQSQLFDQIQKADYSIP------------------SYVSELGKRFIRG----LMDPNPETRLN-VEQALSHPWL
.|.        ..||.. ....|                   ..|. .| .|.     ... .|| |..  ||.| |||.
PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 94179.m00238.AA Ciliate-E2-Unclassified 19-271 26 3.5e-79 269.37 In-house 1-352 (352) Show / Hide 
Range on Protein: 19-271
Range on HMM: 1-352/352
Sequence Identity: 26% (92 aa)

YRFMGPIGKGSFSVVKIVEDSVSGQLFAAKIIPKNKLVASNLSER-----FETEIRIIRQ-----------------LNHPGIVQLYDLFKDENNYYIIM
|..   ||.|.|..|. ....  .|..| |.. |.. ..... ..     .| ..  ...                 ..|| || ... |.|..| ||.|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

ELCSNG-----------------ELYEQIIENERLSEIEAK-----YYMKQILEALCYVHNLG-ICHRDIKPENILLDEQG---HAKISDFGLSRFVTAV
|.| .|                 .|.... ......| .||     .|..|||..|.| |  . |.||||||||||.|..|   . ||.|||.|..    
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

----------------GLAETPCGSPCYA----SPECIRGGSYDGR---KSDMWSCGVLCFAMLTGQLPWTKRNQSQ----------------LFDQIQK
                 .. | ||.|.|     .||...|  ||..   |.|.||.||....||.|..|   .|. |                |...|..
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

ADYSIPS--------YVSELGKRFIR----GLMDPNPETRLNVEQALSHPWL
 ....|.         .|. .| ||.     ... ||. |.. ||.| |||.
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 94179.m00238.AA Pkinase_Tyr 19-231 26 5.5e-18 61.53 Pfam 1-231 (270) Show / Hide 
Range on Protein: 19-231
Range on HMM: 1-231/270
Sequence Identity: 26% (63 aa)

YRFMGPIGKGSFSVVKIVEDSVSGQLF----------AAKIIPKNKLVASN-LSERFETEIRIIRQL-NHPGIVQLYDLFK-DENN--YYIIMELCSNGE
 .|.  .|.|.| .|      . | ..          | |.. |..   .. ..| |  |..| .|| .|| ||.||     ..    .||.||.. .| 
ITFGKKLGEGAFGEV------YKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGD

LYEQIIE----NERLSEIEAKYYMKQILEALCYVHNLGICHRDIKPENILLDEQGHAKISDFGLSRFV-------TAVGLAETPCGSPCYASPECIRGGS
|..   .    ...|.  .   .  || ... | .. .. |||.   |.|..|....||.||||.| .       .. | .  |       .||||. | 
LLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLP---IKWMAPECINYGK

YDGRKSDMWSCGVLCFAMLT-GQLP-WTKRNQSQLFDQI-QK
.   ||| || |||.. ..| |. | .     ......| ..
FT-TKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYED
Kinase 94179.m00238.AA TyrKc 19-271 22 9.5e-17 48.06 SMART 1-280 (280) Show / Hide 
Range on Protein: 19-271
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

YRFMGPIGKGSFSVVKIVEDSVSGQLFAAKIIPKNKLVASNLSERFETEIRIIRQL--NHPGIVQLYDLFKDE-------NNYYIIMELCSNGELYEQII
 ..   .| | | .|   . .   .  | | . ...       | |  |.|| ..|  .|| ||.||    ..         ..|.||....| | . . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

ENER-LSEIEAKYYMKQILEALCYVHNLGICHRDIKPENILLDEQGHAKISDFGLSRFVTAV-GL----AETPC----GSP--C---YASPECIRGGSYD
.... |.  .  ... || .   | |  .. |||.   |.|..|....|||||||||...                  |.         .||||. | . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

GRKSDMWSCGVLCFAMLT-GQLPWTK-----RNQSQLFDQIQKADY-SIPSY--------VSELGKRFIRGLMDPNPETRLNVEQALSHPWL
  ||| || ||... ..| || |.        . .... .... ..  .| .         ..   . ..   . .|| | . ..   |  .
-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF