Gene 80746.m00278 (T.vaginalis)

80746.m00278

Species: T.vaginalis
Alias: 80746.m00278, TvagK0005
External Links:
Annotation:

Classification

Group: Other
Family: Other-Unique

Sequence

Name Sequence Type Origin Length Description Download
80746.m00278.AA Protein None 419 None Fasta, JSON
80746.m00278.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of 80746.m00278.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 80746.m00278.AA AGC 12-262 21 1.3e-93 241.76 In-house 1-395 (395) Show / Hide 
Range on Protein: 12-262
Range on HMM: 1-395/395
Sequence Identity: 21% (86 aa)

YRIESEIGRGSFGAVFKAFDK------VNRQYVCIKQVE----IQNTS---QARLNKE------------IDIHSSLN----------HPNIVK-FYGTY
...   ||.|||| |. . .|       . .|  .| ..    |. .    ... . |             .| . .|          ||.|||  . ..
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

TDESY--TYIVMEYCP---------NG-SLYDSEKYR-NHQIFSLDEARSILND---LGKA-----IQYMHN-KAFIHHD-IKPGNMLFDKNNHIKLCDF
 |...   |.||||.|          |  |. . . | . ..|. ..|| ..     .  .     ..|.|. . .|| | .|| |.|.|.. ||||.||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKI-CGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDF

GLSTSLKDVN--------------------------------------------------PTKKDMCG--TLHYIAPEVLKQRAVSRACDIWS--FGVIL
||.. ... .                                                   . . .||  | .|.|||.|     ..|||.||  .|...
GLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLM

YTLLVGRFPFEADS----------QYEMAQKSM------SADYSIP----------SFVDPVAADLINQCLSIEPKTRPS----------IDKVLEHQFF
| .|.|. || .|.          ..|| || |      . .  .|          ....| | |||...|  .|. |.           .. . .| .|
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
S_TKc 80746.m00278.AA S_TKc 12-262 35 9.4e-93 315.37 SMART 1-231 (231) Show / Hide 
Range on Protein: 12-262
Range on HMM: 1-231/231
Sequence Identity: 35% (93 aa)

YRIESEIGRGSFGAVFKAFDKVNRQYVCIKQVEIQNTSQARLNKEIDIHSSLNHPNIVKFYGTYTDESYTYIVMEYCPN--GSLYD-SEKYRNH---QIF
|.|  .||.|.|| |.|. .|   ..| ||..        .. .||.|... .||||||.|... | .. |.|||||..  |.|.|  .|.. |   . |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

SLDEARSILNDLGKAIQYMHNKAFIHHDIKPGNMLFDKNNHIKLCDFGLSTSLKDVNPTKKDMCGTLHYIAPEVLKQRAVSR-ACDIWSFGVILYTLLVG
.  .||...  . .|..|.|.. .|| |.|| | |.|.  |||.|||||.. |       . .|||..|.|||||     .. .||.||.|.||| .|.|
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCG

RFPFEADSQYEMAQKSMSADYSIPSFVDPVAADLINQCLSIEPKTRPSIDKVLE-------HQFF
. ||.   ...| .| .          .| | |.|..||  .|. ||.. ..|.       |..|
YPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase 80746.m00278.AA Pkinase 12-262 30 2e-91 314.85 Pfam 1-293 (293) Show / Hide 
Range on Protein: 12-262
Range on HMM: 1-293/293
Sequence Identity: 30% (91 aa)

YRIESEIGRGSFGAVFKAFDKVNRQYVCIKQVEIQNTSQARLNK-----EIDIHSSLNHPNIVKFYGTYTDESYTYIVMEYCPNG----SLY----DSEK
|.|.. ||.|||| |.|. .| ... |..|... ....   .       || |. .|||||||..|....|... |.|||||..|    .|.        
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST---

YRNHQIF--SLDEARSILNDLGKAIQYMHNKAFIHHDIKPGNMLFDKNNHI----KLCDFGLSTSL-KDVNPTKKDMCGTLHYIAPEVLK-QRAVSRACD
 ..|  |  | .|.....  . ....|.|.. .|| |.|| | |.|.|.||    |.|||||.  .    |.  .. |||..|.||||.. ..  ....|
-WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

IWSFGVILYTLLVGRFPFEAD------SQYEMAQKSMSADYSIPSFVD---------------------PVAADLINQCLSIEPKTRPSIDKVLEHQFF
.||.|.||| .| ||.||  .      .|..| .. |..... ... .                     . . |.|. ||   || ||... .|.| .|
MWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 80746.m00278.AA CAMK 17-262 22 4.5e-89 287.08 In-house 1-425 (425) Show / Hide 
Range on Protein: 17-262
Range on HMM: 1-425/425
Sequence Identity: 22% (94 aa)

EIGRGSFGAVFKAFDKVNR------------QYVCIKQVEIQ-----------------------------NTSQARLNKEIDIHSS-------LNHPNI
..|||||| |.....| .             | | || .. .                               ..... .||.|...       |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKFYGTYTD-------------------ESYTYIVM---EYCPNG----SLYDSEKYRNH-------------QIFSLDEARSILNDLGKAIQYMHNKAF
.|.| .| |                   ... |.||   |||..|     |.|  . . .               |. .||| .   .  |..|.|..  
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHHDIKPGNMLFDKN-----------------NHIKLCDFGLSTSLKDV-----------------------NPTKKDMCGTLHYIA-PEVLKQ------
.| |.|| | |.|.|                 | ||..|||... ...                        ..  |..|||..|.| ||||..      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------RAVSRACDIWSFGVILYTLLVGRFPFEAD-------------SQYEMAQKSMSADYS-IPSFVDPV-----------------------AAD
        . ....||.|| |||||..|.|..||..|             ..||. .| |...|. .|....|.                       . |
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LINQCLSIEPKTRPSIDKVLEHQFF
||...|  .|. |..|. .|.|...
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 80746.m00278.AA CAMKL 12-262 28 2e-84 269.29 In-house 1-297 (297) Show / Hide 
Range on Protein: 12-262
Range on HMM: 1-297/297
Sequence Identity: 28% (86 aa)

YRIESEIGRGSFGAVFKAFD-KVNRQYVCIKQVEIQNTS--QARLNK--------------EIDIHSSLN---HPNIVKFYGTYTDESY------TYIVM
|||. ..|.|||| |  | . . ... | || .... ..  .  ...              || |...||   ||||.|.| .......       |.||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCPNGS--LYDSEKYRNHQI--FSLDEARSILNDLGKAIQYMHNKAFIHHDIKPGNMLFDKNN--HIKLCDFGLSTSLKDV----NPTKKDMCGTLHYI
|||..|.  |.|  . . |    .. .||| .   .  |..|.|..  .| |||| | |.|.|.   ||..|||.|.  ...    . . |  ||...| 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEVLKQ--R-AVSRACDIWSFGVILYTLLVGRFPFEADS---------QYEMAQKSMSADYSIPSFVDPVAADLINQCLSIEPKTRPSIDKVLEHQFF
|||...   .    .. |||| |||||....|..||..|.          ..  ...    . |...|.  . ||| . |   |. ||.|. ...| ..
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 80746.m00278.AA PLK 12-262 37 3.4e-82 267.47 In-house 1-258 (258) Show / Hide 
Range on Protein: 12-262
Range on HMM: 1-258/258
Sequence Identity: 37% (98 aa)

YRIESEIGRGSFGAVFKAFDKVNRQYVCIK---QVEIQNTSQA-RLNKEIDIHSSLNHPNIVKFYGTYTDESYTYIVMEYCPNGSLYDSEKYRNHQIFSL
|.. . .|.| |  .... |  ..| . ||   .  .| ..|  ....|| ||..|.|||||||.    |... |||.|||.|.|| .  |.|    .. 
YERGHFLGKGGFAKCYEMTDIHTKQVYAIKVVPKSLMQKPHQREKMKQEIEIHRQLHHPNIVKFHHFFEDHENVYIVLEYCHNRSLMHYHKRR-AKRLTE

DEARSILNDLGKAIQYMHNKAFIHHDIKPGNMLFDKNNHIKLCDFGLSTSLKDVNPTKKDMCGTLHYIAPEVL--KQRAVSRACDIWSFGVILYTLLVGR
.|.|...  .  ...|.|..  || |.|.||.....|.|.|..||||.| |.     || ||||  |||||||  .    |   |.||.|.|.||||.|.
PEVRYYMYQIVQGLKYLHQHRIIHRDLKLGNLFLNDNMHVKIGDFGLATRLEYDGERKKTMCGTPNYIAPEVLDGNKQGHSYEVDCWSLGCIMYTLLIGK

FPFEADSQYEMAQKSMSADYSIPSF--VDPVAADLINQCLSIEPKTRPSIDKVLEHQFF
 |||...  |. .. . ..||.|.   . ..|.|||.. |.  | .||.|| .|.|.||
PPFETKDVKETYKRIKHNHYSFPEHCPISDEAKDLIQKMLNWNPDERPTIDQILQHPFF
Kinase 80746.m00278.AA MARK 12-262 33 2.4e-75 245.77 In-house 1-262 (262) Show / Hide 
Range on Protein: 12-262
Range on HMM: 1-262/262
Sequence Identity: 33% (88 aa)

YRIESEIGRGSFGAVFKAFDKVNRQYVCIKQVE---IQN-TSQARLNKEIDIHSSLNHPNIVKFYGTYT--DESY-TYIVMEYCPNGSLYDSEKYRNHQI
|..  .|| ||.. | .| .|  .. |.|| .|   ..   .   .  ||.|...|.||||.|.. .    .|.  .|..|||...|.|||  | . .  
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

FSLDEARSILNDLGKAIQYMHNKAFIHHDIKPGNMLFDKNN--HIKLCDFGLSTSLKDVNPTKKDMCGTLHYIAPEVLKQRAVS-RACDIWSFGVILYTL
 . .||| |   .  |..|.|.|  .| |||| | | |.|.   ||..|||.|.  .  .   .  |||. | |||.....    .. |||| ||.||..
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIP-PGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM

LVGRFPFEADS--QYEMAQKSMSADYSIPSFVDPVAADLINQCLSIEPKTRPSIDKVLEHQFF
..|.|||..|.  . |. .|  . .|.||..| . . .||.. | . |. ||.|. ...| ..
VCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 80746.m00278.AA Ciliate-E2 12-262 26 1.1e-73 251.15 In-house 1-365 (365) Show / Hide 
Range on Protein: 12-262
Range on HMM: 1-365/365
Sequence Identity: 26% (99 aa)

YRIESEIGRGSFGAVFKAFD-KVNRQY-----------------VCIKQVEIQNTSQAR---LNKEIDIH----------------SSLNHPNIVKFYGT
| .   ||.|.|| |.|. . ||..|.                 | ||.... . ..     ...||.|                 ..||||||.|.| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YT--DESYTYIVMEYCPNGSLYD----SEKYRNHQ-----IFSLDEARSILNDLGK---------------AIQYMHNKA-FIHHDIKPGNMLFDKNNHI
.   |... |.|||||  |.|.|    . | |||.      |.. |.. |   . .               |..|.|.|   || |||| | ||     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLCDFGLSTSLKDVNP-------------------TKKDM------------CGTLHYIAPEVLKQRA---------VSRACDIWSFGVILYTLLVGRFP
|..|||||. ..| |                    |  .|            |||..| |||.|.             . .|||||.||||| .| |..|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FEADSQYEMAQKSMSADYSIPSF------------------VDPVAADLINQ----CLSIEPKTRPS-IDKVLEHQFF
|         |. .  ....|..                  ... . |||..    .|  .|. |.. ....|.|..|
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 80746.m00278.AA PLK-Unclassified 12-262 35 1e-71 244.54 In-house 1-264 (264) Show / Hide 
Range on Protein: 12-262
Range on HMM: 1-264/264
Sequence Identity: 35% (95 aa)

YRIESEIGRGSFGAVFKAFDKVNRQYVCIKQVE---IQNTSQ-ARLNKEIDIHSSLNHPNIVKFYGTYTDESYTYIVMEYCPNGSLYDSEKYRNHQIFSL
|.. . .| | |  .... .  . .   .| .    .. ...  .|. || ||.||.|.|||||.    |... ||..||||||.| .  |.|| |.|  
YHRGHFLGKGGFAKCYQVKNIETKKIYAAKIIPKSSLTKNRARQKLISEIKIHKSLHHKNIVKFEHCFEDHENVYILLEYCPNGTLMEYIKRRNFQLFEK

-----DEARSILNDLGKAIQYMHNKAFIHHDIKPGNMLFDKNNHIKLCDFGLSTSLKDVNPTKKDMCGTLHYIAPEVLKQRA--VSRACDIWSFGVILYT
     .|.....  . .|..|.|..  || | |.|| ... |. .|.|||||.| |.     ||  |||  |||||.|  .    |   |.||||.||||
KRLTEYEVKCYTYQIVQALKYLHQNRIIHRDLKLGNIFLNDNMEVKICDFGLATKLENDGEKKKTICGTPNYIAPEILDGKHQGHSYEVDCWSFGCILYT

LLVGRFPFEADSQYEMAQKSMSADYSIPSFVD--PVAADLINQCLSIEPKTRPSIDKVLEHQFF
||.|. |||. .     .|  . .|| |  .     | ||| . |.. |..||.||  ..| |.
LLIGKPPFETKDVKQTYKKIKCNQYSFPEPCHISDNAKDLIQHILNWNPDQRPTIDQIMMHPFY
Kinase 80746.m00278.AA Ciliate-E2-Unclassified 12-262 25 1.3e-69 237.54 In-house 1-352 (352) Show / Hide 
Range on Protein: 12-262
Range on HMM: 1-352/352
Sequence Identity: 25% (90 aa)

YRIESEIGRGSFGAVFKAFDKVNRQY--------VCIKQVEIQNTSQARLNKEIDIHSSLN-------------------HPNIVKFYGTYTDESYTYIV
|.|   ||.|.|| |.|. .| . ||        . |. . ...... ... |...  ...                   ||.|||.. . .|. . |||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEYCPNGSLYDSEKYRNH---------------QIFSLDEAR-----SILNDLGKAIQYMHNKA-FIHHDIKPGNMLFDKNN---HIKLCDFGLSTSLKD
||||..|.| .  | |..               .||.  .|.      ..  . ....|.| |  .|| |||| | |||.|.   .||..|||.|  ...
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

V---------------NPTKKDMCGTLHYI----APEVLKQRAVS----RACDIWSFGVILYTLLVGRFPFEADSQYE----------------MAQKSM
                .   ...|||. |.    |||||..   .     .|||||.||||| .| |..||.. ....                . |. .
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

SADYSIPS--------FVDPVAADLIN----QCLSIEPKTRPSIDKVLEHQFF
  ....|.         ..| |.|.||    ..|   |. |......|.|..|
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 80746.m00278.AA STE 12-262 23 1.1e-68 234.44 In-house 1-359 (359) Show / Hide 
Range on Protein: 12-262
Range on HMM: 1-359/359
Sequence Identity: 23% (86 aa)

YRIESEIGRGSFGAVFKAFDKV---------------NRQYVCIKQVEIQN------------------TSQARLNKEIDIHSSLN--HPNIVKFYGTYT
... ..||.|.|| |.|| ..                . ... |||....|                  . . .. |||.|.. .|  ||||||.||.| 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DE-------SYTYIVMEYCPNGSLYDSEK-YRNHQI-----------FSLDEARSILNDLGKA-IQYMHNKAFIHHDIKPGNMLFDKNNHIKLCDFGLST
.|       .. .|.|||...||| |  | .  ..            |. .. . |. .. |.  .| |..  || ||||.| |.     .||||||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

SLKDVNP----------------TKKDMCGTLHYIAPEVLKQ------RAVSRACDIWSFGVILYTLLVGRFPFEADSQY----EMAQKSMSAD------
.| | ..                  . ..||  . ||||..|         .. |||||.|  .  .. |. |.   .      ...... ...      
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---YSIPSFVD----------------------PVAADLINQCLSIEPKTRPSIDKVLE--HQFF
     .|.. |                      |   | ||.|| ..|. ||. .. |.  | |.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 80746.m00278.AA RSK 41-262 29 1.4e-66 227.48 In-house 34-278 (278) Show / Hide 
Range on Protein: 41-262
Range on HMM: 34-278/278
Sequence Identity: 29% (72 aa)

KQVEIQN-TSQARLNKEIDIHSSLN-HPNIVKFYGTYTDESYTYIVMEYCPNGSLYDSEKYRNH-QIFSLDEARSILNDLGKAIQYMHNKAFIHHDIKPG
| . .|. .....  .|..| .  . ||.||. . .. .|...|..||||. | |..  . . |   || |||. ..  . .|....| . .|| |.|| 
KAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPE

NMLFDK---NNHIKLCDFGLSTS--LKDVNPTKKDMCGTLHYIAPEVLK----QRAVSRACDIWSFGVILYTLLVGRFPFEA---DSQYEMAQKSMSAD-
|.|.|    . ||||.|||..    ... ..|..  |.|..|.|||.||    |.. ..|||.||.||..|..|.|. || .   ... |  .. .... 
NILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMT-FCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKF

-YSIP--SFVDPVAADLINQCLSIEPKTRPS-----IDKVLEHQFF
  ..|  ... . | |||...|  .|. |..     .. ...|..|
SLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 80746.m00278.AA TyrKc 12-262 23 2.3e-19 71.59 SMART 1-280 (280) Show / Hide 
Range on Protein: 12-262
Range on HMM: 1-280/280
Sequence Identity: 23% (68 aa)

YRIESEIGRGSFGAVFKAFDKVNRQYVCIKQVEIQNTSQARLNKEIDIHSSL--NHPNIVKFYGTYTDE-------SYTYIVMEYCPNGSLYDSEKYRNH
 . . ..|.| || |.|.  |   . | .| .      .. . .|. | ..|  .|||||..||  |..          .|||||.|.|.| |  ... .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

QIFSLDEARSILNDLGKAIQYMHNKAFIHHDIKPGNMLFDKNNHIKLCDFGLSTSLKDV------NPTKKD----MC---GTLHYIAPEVLKQRAVSRAC
. .....  |.  .  .  .| | | .|| |.   | | ..|...| .|||||  ..|         ...      .     .   |||... .  . . 
K-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS

DIWSFGVILY---TLLVGRFPFEA-----DSQYEMAQKSMSADYSIPSFV----------DPVAADLINQCLSIEPKTRPSIDKVLEHQFF
|.||||| ..   |.  |  | .       | .|. .. .. ..  .             | .   .. ||   .|. ||.   .  |..|
DVWSFGVCMWEIFTY--GQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI--HECF
Kinase 80746.m00278.AA Pkinase_Tyr 12-95 31 3.6e-18 62.18 Pfam 1-96 (270) Show / Hide 
Range on Protein: 12-95
Range on HMM: 1-96/270
Sequence Identity: 31% (30 aa)

YRIESEIGRGSFGAVFKAFDK----VNRQYVCIKQVEIQNTSQ----ARLNKEIDIHSSL-NHPNIVKFYGTYT-DESY--TYIVMEYCPNGSLYD
 ..  ..|.|.|| |.|.  |     ... | .| .  . ...    . . .|. | ..| .|||||..||  | ..     ||||||.|.|.|.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD
Kinase 80746.m00278.AA Pkinase_Tyr 142-199 29 6e-06 20.8 Pfam 145-205 (270) Show / Hide 
Range on Protein: 142-199
Range on HMM: 145-205/270
Sequence Identity: 29% (18 aa)

DKNNHIKLCDFGLSTSL--KDVN-PTKKDMCGTLHYIAPEVLKQRAVSRACDIWSFGVILY
..||..| |||||.  .  .|    ....        |||... .  . . |.||||| ..
TENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMW