Gene 93793.m00239 (T.vaginalis)

93793.m00239

Species: T.vaginalis
Alias: TvagK0867, 93793.m00239
External Links:
Annotation:

Classification

Group: Other
Family: WNK

Sequence

Name Sequence Type Origin Length Description Download
93793.m00239.AA Protein None 324 None Fasta, JSON
93793.m00239.kin_dom Protein Kinase Domain None 257 None Fasta, JSON

Protein domain

Protein domains of 93793.m00239.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 93793.m00239.AA WNK 11-263 39 1.5e-92 299.28 In-house 5-261 (261) Show / Hide 
Range on Protein: 11-263
Range on HMM: 5-261/261
Sequence Identity: 39% (103 aa)

EFIGSGSYKIVYRAYDQEEGIEVAWNEIRLDKFNEVESNQIKQEISILHQLDHPSILKIFSAWRDL--SRNSMIFITEFFSNGTIRAYVSDVVKAPKRSV
| .| ||.| |||..| | ..||||.|... | .  |   .| |. .| .| || |....  |      .   . .||    || . |     |   . |
EEVGRGSFKTVYRGLDTETWVEVAWCELQDQKLSKNERQRFKEEAEMLKKLQHPNIVRFYDYWESVLCGKKCIVLVTELMTSGTLKTYLKRFKKMKPK-V

ISKWCKQILEGLNYIHTHDP-PVIHRDLKCDNLFIDASEGIVKIGDFGLS-KITETGQAASCMGTPAYTAPEVYLGNYTTKADIWSFGLCVLEMMTGETP
  .||.||| ||...||  | |.||||||||| ||    | ||||| ||      .  | | .||| . |||.|   | .  |. .|| |.||| |.|.|
LRSWCRQILKGLHFLHTRQPHPIIHRDLKCDNIFITGTTGSVKIGDLGLAVTLKNSSFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYP

YSECVGIGAIYLKVSGGYMPASLAKVSDPVIADFITMCLLPQE-DRPSAADLLEHNLI
|||| .   || ||. |  |.|..|. .| . ..|  |.  .. .|||...||.|   
YSECQNAAQIYRKVTQGIKPNSFQKIQNPEVKEIIEKCIRHNKEERPSIQQLLNHDFF
S_TKc 93793.m00239.AA S_TKc 7-263 27 1.2e-61 212.01 SMART 1-231 (231) Show / Hide 
Range on Protein: 7-263
Range on HMM: 1-231/231
Sequence Identity: 27% (74 aa)

YRRCEFIGSGSYKIVYRAYDQEEGIEVAWNEIRLDKFNEVESNQIKQEISILHQLDHPSILKIFSAWRDLSRNSMIFITEFFSN--GTIRAYVSDVVKAP
|.  . ||.|..  ||.... . | .||  .|.         ..|..||.||.. .|| | |.. ...|   ... ...|. ..  |. . |  .  . .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

-----KRSVISKWCKQILEGLNYIHTHDPPVIHRDLKCDNLFIDASEGIVKIGDFGLSKITETGQAASCMGTPAYTAPEVYLGNYTT-KADIWSFGLCVL
        .. ....||...|.|.| |   .|||||| .|...|     .||.||||...       .. ||| | ||||    |.. |.|.||.| .. 
LRFPFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE---HIKICDFGLARQL-----TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILY

EMMTGETPYSECVGIGAIYLKVSGGYMPASLAKVSDPVIADFITMCLL-PQEDRPSAADLLE-------HNLI
||..|..|..    . ... |.             .|   |||  ||    |.||.| ..|.       |  .
EMLCGYPPFP---QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 93793.m00239.AA STE 7-263 23 7.6e-61 208.46 In-house 1-359 (359) Show / Hide 
Range on Protein: 7-263
Range on HMM: 1-359/359
Sequence Identity: 23% (85 aa)

YRRCEFIGSGSYKIVYRAYDQE---------------EGIEVAWNEIRLDKFN---------------EVESNQIKQEISILHQLD--HPSILKIFSAWR
... |.||.|..  ||.|.. .                |  .|  ...|.. |               . | .||..||.|.....  || | | . .  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DLS-----RNSMIFITEFFSNGTIRAYVSDVVKAPKR-------------SVISKWCKQILEG-LNYIHTHDPPVIHRDLKCDNLFIDASEGIVKIGDFG
. .     ...   . |. ..|...  .  . . .|.             |.|.. |.|||.| |.|.| |   .||||.|..| ..      ||. |||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH--IIHRDIKPANILL------VKLCDFG

LSK-ITE---------------TG--QAASCMGTPAYTAPEVYLGN-------YTTKADIWSFGLCVLEMMTGETPYSECVGIGAIYLKVSGGYMPA---
... .|.               |.  .  .. ||| . |||| ..|       |.||.||||.|....|| ||. |...     |....  ...| .   
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFE

-------SLAKVSD----------------------PVIADFITMCLLPQED-RPSAADLLE--HNLI
          .  |                      |   |||  ||    . ||.| .||.  |  |
QLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 93793.m00239.AA Pkinase 7-263 25 6.1e-52 183.68 Pfam 1-293 (293) Show / Hide 
Range on Protein: 7-263
Range on HMM: 1-293/293
Sequence Identity: 25% (77 aa)

YRRCEFIGSGSYKIVYRAYDQEEGIEVAWNEIRLDKFNEVESNQIKQ--EISILHQLDHPSILKIFSAWRDLSRNSMIFITEFFSNG----TIRAYVS-D
|.. . |||||.  ||..... .|..||  .|.... .. .  .     ||.|.. |.|| |.... ...|  .... ...|.  .|       .|.| .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTW

VVKAP--KRSVISKWCKQILEGLNYIHTHDPPVIHRDLKCDNLFIDASEGIV----KIGDFGLSK---ITETGQAASCMGTPAYTAPEVYL--GNYTTKA
  ..      .. ....|||.||.|.| .   .|||||| .|..|| ..| .    ||.||||.|   .   . . .  ||| | |||| .    |..|.
RHGCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DIWSFGLCVLEMMTGETPYSEC-----VGIGAIYLKVSGGYMPASLAKVSD-------------------PVIADFITMCL-LPQEDRPSAADLLEHNLI
|.||.|. . ||..|..|....     .   ... .. |.  . .  . ..                   .   |||. || .  ..||.|...|.|  .
DMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 93793.m00239.AA TKL 13-261 19 6.2e-48 165.56 In-house 1-364 (364) Show / Hide 
Range on Protein: 13-261
Range on HMM: 1-364/364
Sequence Identity: 19% (71 aa)

IGSGSYKIVYRAYDQEEG--------IEVAWNEIRLDKFNEVES-------------------------NQIKQEISILHQLDHPSILKIFSAWRDLS--
||||.. .||... . .|         .||   .. .  .| ..                          ....|| ....|.|| |...  .  . .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

---------RNSMIFITEFFSNGTIRAYVSDVVKAPKRSVISKWCKQILEGLNYIHTHD------PPVIHRDLKCDNLFIDA-------------SEGIV
          . . ...|. ..|. . |.         ... .|...|  |.|| |...      ||.|||||| .|...|              ... .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KIGDFGLSK-ITETG--------------------QAASCMGTPAYTAPEVYLGN-----------------YTTKADIWSFGLCVLEMMTGETPYSECV
||.|||||. ....|                    .  .. |||.. ||||  |.                 |..|.|..|||..  |..|...||..  
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

GIGAI---------YLKVSGGYMPASL-----------AKVSDPVIADFITMCLLP-QEDRPSAADLLEHN
 .  |         .. .. |. |               .  .| ... ...|  .  |.|||. ..|.. 
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 93793.m00239.AA Ciliate-E2 7-263 19 9.6e-46 155.0 In-house 1-365 (365) Show / Hide 
Range on Protein: 7-263
Range on HMM: 1-365/365
Sequence Identity: 19% (76 aa)

YRRCEFIGSGSYKIVYRAYDQEEGIEVAWNEIRLDK-------------------FNEVESNQIKQEISILH----------------QLDHPSILKIFS
|   . ||.|.. .||.. . ... ..| . |. .|                   ... . .||||||.|.                 ||.|| |.|.. 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

AWRDLSRNSMIFITEFFSNGTIRAYVSDV-VKAPKR---------SVISKWCKQILE---------------GLNYIHTHDPPVIHRDLKCDNLFIDASE
.. . ..|.. ...|... |. . |  .   | ..            |..  ||||.               .|.|.|   . .||||.| .|...    
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN-IIHRDIKPENILF----

GIVKIGDFGLSK-----------------ITETG-----------------QAASCMGTPAYTAPEVYLGN----------YTTKADIWSFGLCVLEMMT
  .|| ||||||                 ... .                 .. .. ||| | |||.. |           |..|.||||.| .  ||..
--IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

GETPYSECVGIGAIYLKVSGGYMPASLAKVSDPVIA----------------------------DFIT-----MCLLPQEDRPS-AADLLEHNLI
|..|.                     . .  .  |                             |.|      |    .| |.. . ..|.|  .
GKPPF---------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 93793.m00239.AA CAMK 12-263 16 3.3e-42 133.33 In-house 1-425 (425) Show / Hide 
Range on Protein: 12-263
Range on HMM: 1-425/425
Sequence Identity: 16% (69 aa)

FIGSGSYKIVYRAYDQEEG------------IEVAWNEIRLDKFN--------------------------EVESNQIKQEISILHQ-------LDHPSI
 .|.||. .|..... . .             .||   |  .|                            ..   ....||.|. .       |||| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LKIFSAWRDLS-----------------RNSMIFIT---EFFSNG----TIRAYVSDV-----------VKAPKRSV----ISKWCKQILEGLNYIHTHD
.|.. .. | .                 .. |....   |. |.|     .  |. .            .   .. .     ... .||.....|.| |.
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSHN

PPVIHRDLKCDNLFIDASE----------------GIVKIGDFGLSKITETGQ-------------------------AASCMGTPAYTA-PEVYLGN--
  ..|||||..|. .| ..                . .|| |||.... . |.                            . |||.| | ||| .|.  
--IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGH

-------------YTTKADIWSFGLCVLEMMTGETPYSEC------------VGIGAIYLKVSGGYMPASLAKVSD----------------------PV
             |. |.|.|| |     | .|. |. .             . .  .. |.  |       ..|.                      . 
CNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQE

IADFITMCLLP-QEDRPSAADLLEHNLI
  |.|  .| .  |.|..... |.|  .
CKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 93793.m00239.AA STE11 107-263 34 2.4e-40 140.35 In-house 116-303 (303) Show / Hide 
Range on Protein: 107-263
Range on HMM: 116-303/303
Sequence Identity: 34% (66 aa)

SVISKWCKQILEGLNYIHTHDPPVIHRDLKCDNLFIDASEGI-VKIGDFGLSKITE-------------------TGQAA-SCMGTPAYTAPEVYL-GN-
.||.|  |||||||.| | |   .||||.| .|...| |.|. .|..||| .|  .                   ||    | ||||.. ||||.  .  
MVIRKYTKQILEGLQYLHSHG--IIHRDIKGANILLD-SDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPMWMAPEVIKQEGR

--YTTKADIWSFGLCVLEMMTGETPYSECVG--IGAIYLKVSG-GYMPASLAKVSD-----PVIADFITMCLLPQED-RPSAADLLEHNLI
  |..||||||.| .|.||.||  |....    . |..  ..| . .|    ..|      .   ||.  |. ..   ||.|..||.|. |
DGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQHPFI
Kinase 93793.m00239.AA NRBP 14-264 33 2.1e-39 136.11 In-house 3-261 (261) Show / Hide 
Range on Protein: 14-264
Range on HMM: 3-261/261
Sequence Identity: 33% (88 aa)

GSGSYKIVYRAYDQEEGIEVAWNEIRLDKFNEVESN--QIKQEISILHQLDHPSILKIFSAWRDLSRNS--MIFITEFFSNGTIRAYVSDVVKAPKRSVI
     ...| | |.|||.|| |||..  .  . ...  .|.|    | ||||. | |.   | | ...   .|||||. | | .....  . |. |.  .
DVPGIDCAYLAMDTEEGVEVVWNEVQFSERKNFKAQEEKIRQVFDNLIQLDHQNIVKFHKYWTDTKEEKPRVIFITEYMSSGSMKQFLKKTKKNHKNMNE

S---KWCKQILEGLNYIHTHDPPVIHRDLKCDNLFIDASEGIVKIGDFGLSKITETGQAA-SCMGTPAYTAPEVY---LGNYTTKADIWSFGLCVLEMMT
    .|| |||  |.|.|. |||.||  | || .||    |..|||     .| .  ...   |    . |||       . || .||.|||.| |||  
KAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQH-NGLIKIGCVWPDAIHHHVRTCREEMRNMHFFAPEYGILEVTDLTTAVDIYSFGMCALEMAV

GETPYSECVGIGAIYLKVSGGYMPASLAKVSDPVIADFITMCLLPQ-EDRPSAADLLEHNLIL
 |   | |    . |  |.   .  .   ..||.  |||  || .. ..|||| .|| |....
LEI-QSGCQNGESEY--VTEEAIQRAIHSLEDPMQRDFIRKCLQKDPARRPSARELLFHQILF
Kinase 93793.m00239.AA MEKK2 7-263 32 3.6e-37 129.79 In-house 1-262 (262) Show / Hide 
Range on Protein: 7-263
Range on HMM: 1-262/262
Sequence Identity: 32% (88 aa)

YRRCEFIGSGSYKIVYRAYDQEEGIEVAWNEIRLDKFN---EVESNQIKQEISILHQLDHPSILKIFSAWRDLSRNSMIFITEFFSNGTIRAYVSDVVKA
.||   .| | .  ||  || . | |.|   .. |  |     | . ...|| .|. | |. | . .   ||     .    |. . | ..  .  .  |
WRRGKLLGQGAFGRVYVCYDVDTGRELAVKQVQFDPDNPETRKEVQALECEIQLLKNLQHERIVQYYGCLRDNQEKTLSIFMEYMPGGSVKDQLK-AYGA

PKRSVISKWCKQILEGLNYIHTHDPPVIHRDLKCDNLFIDASEGIVKIGDFGLSKITETGQAA-----SCMGTPAYTAPEVYLGN-YTTKADIWSFGLCV
   .|  |. .|||||. |.| |   ..|||.|  |.  | | | ||.|||| ||   |         |  ||| . .|||  |  |  |||.|| |  |
LTETVTRKYTRQILEGMHYLHDHM--IVHRDIKGANILRD-SSGNVKLGDFGASKRLQTICMHITGMKSVTGTPYWMSPEVINGEGYGRKADVWSIGCTV

LEMMTGETPYSECVGIGAIYLKVSGGYMPASLAKVSDPVIADFITMCLLPQED-RPSAADLLEHNLI
 ||.|   |. |   . ||.        |    .||.    ||.. |       ||||..|| |. .
VEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPQHVSQ-HARDFLKRCFVEIKQDRPSAEELLRHHFV
Kinase 93793.m00239.AA NEK 111-202 38 3.4e-29 100.2 In-house 118-219 (286) Show / Hide 
Range on Protein: 111-202
Range on HMM: 118-219/286
Sequence Identity: 38% (39 aa)

KWCKQILEGLNYIHTH-DP--PVIHRDLKCDNLFIDASEG---IVKIGDFGLSKITETG--QAAS-CMGTPAYTAPEVY-LGNYTTKADIWSFGLCVLEM
.|. |.. .|.|.| .  |   ..|||.|. |.|....     .|||||||.||. ...   | . . ||| | .|||     |. |.||||.| .. ||
DWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKPYNNKSDIWSLGCVLYEM

MT
.|
CT
Kinase 93793.m00239.AA STE20 113-263 34 6.9e-28 98.98 In-house 123-288 (288) Show / Hide 
Range on Protein: 113-263
Range on HMM: 123-288/288
Sequence Identity: 34% (59 aa)

CKQILEGLNYIHTHDPPVIHRDLKCDNLFIDASEGIVKIGDFG-LSKITE----T--GQAASCMGTPAYTAPEVYLGN------YTTKADIWSFGLCVLE
|...|.||.|.| .   .||||.| ||  .. ..| ||. |||  ...|.    |  ..  .  ||| . |||| ...      |..|.||||.| . .|
CREVLQGLDYLHSNH--IIHRDIKADNILLT-EDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGPDKGYDYKCDIWSLGITAIE

MMTGETPYSECVGIGAIYLKVSGGYMPASLA-----KVSDPVIADFITMCL-LPQEDRPSAADLLEHNLI
| .|| ||...    |.... ...  |  |      | | |   ||.  ||    |.||.| .||.|  |
MAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWS-PEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase 93793.m00239.AA Pkinase_Tyr 53-210 27 6e-18 61.42 Pfam 52-219 (270) Show / Hide 
Range on Protein: 53-210
Range on HMM: 52-219/270
Sequence Identity: 27% (47 aa)

QEISILHQL-DHPSILKIFSAWRDLSRN-SMIFITEFFSNGTIRAYVSDV---VKAPKRSVISKWCKQILEGLNYIHTHDPPVIHRDLKCDNLFIDASEG
.|..|..|| .|| |..   .  | ..  ... ..|.  .|  . |  .     .... . . ..| || .|..| . .    ||||| . |  .. .  
REAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTENN-

IVKIGDFGLSKIT----ET-GQAASCMGTPAYTAPE--VYLGNYTTKADIWSFGLCVLEMMT-GETP-YSEC
.|||.||||..      .   .. ...     .|||   |   .||| |.|||| .  |..| ||.| | ..
VVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSDVWSFGVLMWEIFTYGEQPTYPGM
Kinase 93793.m00239.AA TyrKc 7-263 22 8.4e-18 65.12 SMART 1-280 (280) Show / Hide 
Range on Protein: 7-263
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

YRRCEFIGSGSYKIVYRAYDQEEGIEVAWNEIRLDKFNEVESNQIKQEISILHQL--DHPSILKIFSAWRDLSR-----NSMIFITEFFSNGTIRAYVSD
 .  . .|.| . .||..      |.||   .. |.        . .|..|...|  .|| |.... . .. .|       .  ..|. ..|  . |  .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

VVKAPKRSVISKWCKQILEGLNYIHTHDPPVIHRDLKCDNLFIDASEGIVKIGDFGLSKITETG---------QAA----SCM--GTPAYTAPEVYLGN-
  .  . .   ..| || .| .|.| .  ..||||| . |  ...   .|||.|||||.  . .           .    ..        .|||.   . 
HRPKLCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YTTKADIWSFGLCVLEMMT-GETPYSE-----CVGIGAIYLKVSGGYMPASLAKV------SDPVIADFITMCLLP-QEDRPSAADLLEHNLI
.||| |.|||| |  |..| |..||..     .  . .| .  .|..||              . . . ...|     ||||. ...  | ..
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 93793.m00239.AA STE11 7-64 24 4.3e-09 29.33 In-house 1-70 (303) Show / Hide 
Range on Protein: 7-64
Range on HMM: 1-70/303
Sequence Identity: 24% (17 aa)

YRRCEFIGSGSYKIVYRAYDQEEGIEVAWNEIRLDKFN------EVESNQ------IKQEISILHQLDHP
....|.||.|..  ||....   | ..|  .|.... |      | | ..      |..||... .|.|.
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHK
Kinase 93793.m00239.AA NEK 7-66 30 5.6e-09 28.16 In-house 1-66 (286) Show / Hide 
Range on Protein: 7-66
Range on HMM: 1-66/286
Sequence Identity: 30% (20 aa)

YRRCEFIGSGSYKIVYRAYDQEEGIE-----VAWNEIRLDKFNEVESNQIK-QEISILHQLDHPSI
|.. . ||.||.  ||.. ... | .     ..| .| ... .| |  .   .|. || ||.|| |
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNI
Kinase 93793.m00239.AA STE20 7-72 37 2.6e-08 26.81 In-house 1-72 (288) Show / Hide 
Range on Protein: 7-72
Range on HMM: 1-72/288
Sequence Identity: 37% (27 aa)

YRRCEFIGSGSYKIVYRAYDQEEGIE----VAWNEIRLDKFNE--VESNQIKQEISILHQLDHPSILKIFSA
|   | ||.|||  ||.||. . | .    ||   . |.| ..   | . |..||||. |..|| | | . .
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGS
Kinase 93793.m00239.AA NEK 249-263 46 0.008636 6.12 In-house 272-286 (286) Show / Hide 
Range on Protein: 249-263
Range on HMM: 272-286/286
Sequence Identity: 46% (7 aa)

EDRPSAADLLEHNLI
|.|||. ..||. .|
EQRPSCNQILEMPFI