Gene 85851.m00046 (T.vaginalis)

85851.m00046

Species: T.vaginalis
Alias: 85851.m00046, TvagK0532
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag2

Sequence

Name Sequence Type Origin Length Description Download
85851.m00046.AA Protein None 335 None Fasta, JSON
85851.m00046.kin_dom Protein Kinase Domain None 248 None Fasta, JSON

Protein domain

Protein domains of 85851.m00046.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 85851.m00046.AA CAMKL 24-269 32 1.2e-76 244.08 In-house 1-292 (297) Show / Hide 
Range on Protein: 24-269
Range on HMM: 1-292/297
Sequence Identity: 32% (95 aa)

YRVIKVIGKGAFAAVVLALN-ISTEEYVAIKIIDRDSIIKQGYLLY------------LENELRLSSRFD---HPNIAKVHEVIYTSEN------IMIVM
||..|..|||.|. | ||.. . |.| |||||||.. | .  . .             .. | .. ....   |||| | .|||.|.|.      | .||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYLPNGD--LSNLL--TRGII--FGTNEQFKFASQIVSALEYLHDRGISHRDIKPENMLFDDEF--NVKLVDFGLSKE-N-C----SS-LQTYCGTPVYM
|| ..|.  | . .   ..    .  .|  ..  |||||..|.|..|| |||||||| |.|.    |.|..|||.| .   |       | | ||.| ||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEIACG--KEYDGAKADIWAFGITFHAFCFGMLPYPENDD--------RSMLSDIKKGNVNIHPNATGTIKQILDLTLNPDSAKRATAKELL
||||  |  |.||| |.|||. |..  |  .| ||  . ..        . .. ... .. .|..      ....   |...  ||.|.....
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCGYYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIM
S_TKc 85851.m00046.AA S_TKc 24-277 31 1.8e-76 261.24 SMART 1-231 (231) Show / Hide 
Range on Protein: 24-277
Range on HMM: 1-231/231
Sequence Identity: 31% (83 aa)

YRVIKVIGKGAFAAVVLALNISTEEYVAIKIIDRDSIIKQGYLLYLENELRLSSRFDHPNIAKVHEVIYTSENIMIVMEYLPN--GDLSNLLTRGII---
|.....||||||. | .. ...| ..||||||.            ...|... .. .|||| | ..|... ... .||||...  |||  .. .      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FGTNEQFKFASQIVSALEYLHDRGISHRDIKPENMLFDDEFNVKLVDFGLSKENCSSLQTYCGTPVYMAPEIACGKEYDGAKADIWAFGITFHAFCF
   |   .  ... ||..||||.|..|| |||.|||| |.|.  ..|. ||||...      |.|||| |||||.     |...|.|.|..|...  .. 
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

GMLPYPENDDRSMLSDIKKGNVNIHPNATGTIKQILDLTLNPDSAKRATAKELLD----IIHSSEF
|  |.|   .  |. .. .         .   |....  |. | .|| || |.|     |     |
GYPPFP---QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase 85851.m00046.AA Pkinase 24-272 28 1.1e-73 255.92 Pfam 1-293 (293) Show / Hide 
Range on Protein: 24-272
Range on HMM: 1-293/293
Sequence Identity: 28% (85 aa)

YRVIKVIGKGAFAAVVLALNISTEEYVAIKIIDRDSIIK--QGYLLYLENELRLSSRFDHPNIAKVHEVIYTSENIMIVMEYLPNG----DLSNLLT--R
|.....||.|.|. | .. ...|.. ||.|||..... .  . ... | .|...  |..|||| . ... ... .| .||||...|    ||. ...  |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

GIIF--GTNEQFKFASQIVSALEYLHDRGISHRDIKPENMLFDDEFNV----KLVDFGLS----KENCSSLQTYCGTPVYMAPEIACGKEYDGAKADIWA
.  |    .|  ... ||...|||.|..|| |||.|||| |.|.. ..    |. ||||.      | | ..|.|||| |||||.  | .|.| |.|.|.
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

FGITFHAFCFGMLPYPEN------DDRSMLSDIKKGNVNIHPNAT---------------------GTIKQILDLTLNPDSAKRATAKELLDI--I
.|.... ...| .|.|.       |.. |.  |... .  .   .                      . |....  |..| .|| ||...|    .
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 85851.m00046.AA CAMK 29-270 20 1.5e-71 229.65 In-house 1-421 (425) Show / Hide 
Range on Protein: 29-270
Range on HMM: 1-421/425
Sequence Identity: 20% (86 aa)

VIGKGAFAAVVLALNISTE------------EYVAIKIIDRDSIIK------------------------QGYLLY-LENELRLSSR-------FDHPNI
..|.|.|. | |. ...|             . |||||||.. . .                        ... .  ...|... ..        |||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

AKVHEVIY------------TSEN--------IMIVM---EYLPNG----DLSNLLTR----------GIIFGTNEQF------KFASQIVSALEYLHDR
 | .||.             | ..        . .||   || ..|    || . ...          . |   .  |      ..  ||.||..|.|..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSH

GISHRDIKPENMLFDDE-----------------FNVKLVDFGLSKENCS--------------------------SLQTYCGTPVYMA-PEIACG----
.| |||.|||| |.||                  .|.|..|||....  .                           ..|.|||| ||| ||.  |    
NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

---------KEYDGAKADIWAFGITFHAFCFGMLPYPEN-------------DDRSMLSDIKKGNVN-IHPNATG-----------------------TI
         |.|.| |.|.|. |.   .   | .|. .              .|. ..  |.||. . ..|  ..                         
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC

KQILDLTLNPDSAKRATAKELLD
|. .   |..|  ||.|... |.
KDLIRKMLQVDPEKRMTIEQCLN
Kinase 85851.m00046.AA AMPK 24-268 36 6.9e-71 209.7 In-house 1-248 (254) Show / Hide 
Range on Protein: 24-268
Range on HMM: 1-248/254
Sequence Identity: 36% (91 aa)

YRVIKVIGKGAFAAVVLALNISTEEYVAIKIIDRDSIIKQGYLLYLENELRLSSRFDHPNIAKVHEVI-YTSENIMIVMEYLPNGDLSNLLTRGIIFGTN
| . | ||.|.|  | ..  | | |.|||||.... |..|     ...|...   | ||.| .  |||  | . | .|||| ..|.|    ..       
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EQFKFASQIVSALEYLHDRGISHRDIKPENMLFDDEFNVKLVDFGLS---KENCSSLQTYCGTPVYMAPEIACGKEYDGAKADIWAFGITFHAFCFGMLP
|  .|  ||.|..||.|. .|.||| ||||.|.|.. |.|.||||||   |..   | | || | | |||.  || | | . |||  |.   |.  | ||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDG-EFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLP

YPENDDRSMLSDIKKGNVNIHPNATGTIKQILDLTLNPDSAKRATAKEL
  . . ..    ||.| . |  . .  .|...   |..|  ||.| ...
FDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDI
Kinase 85851.m00046.AA Ciliate-E2 24-270 24 8.4e-65 221.38 In-house 1-361 (365) Show / Hide 
Range on Protein: 24-270
Range on HMM: 1-361/365
Sequence Identity: 24% (92 aa)

YRVIKVIGKGAFAAVVLALNISTEEYVAIKIIDRDS------------------IIKQGYLLYLENELRLS----------------SRFDHPNIAKVHE
| .||.||.|.|. | .. .... . .|||||| .                   |.|.  . ....|...                 .. .|||| | .|
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

VIY--TSENIMIVMEYLPNGDLSNLLTRGIIFG-----------TNEQFKFASQIVS---------------ALEYLHDRG-ISHRDIKPENMLFDDEFN
. .  . .|| .||||.  |||  ..    ..             .|  ..  ||..               |||||| .. | |||||||| ||     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

VKLVDFGLSK----ENCSSL------------------------------QTYCGTPVYMAPEIACGKEYDG--------AKADIWAFGITFHAFCFGML
.|..||||||    .|.  .                              .|.|||| ||||||  ||.||.         |.|||..|.... ..|| .
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PYPENDDRSMLSDIKKGNVN------------------IHPNATGTIKQILDL----TLNPDSAKRAT-AKELLD
|.        .  ||.....                  .. . .   |...       |. |  || | ....|.
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN
Kinase 85851.m00046.AA ULK 24-253 26 1.3e-61 211.04 In-house 1-300 (324) Show / Hide 
Range on Protein: 24-253
Range on HMM: 1-300/324
Sequence Identity: 26% (80 aa)

YRVIKVIGKGAFA-AVVLALNISTE---EYVAIKIIDRDSIIKQGYL-------LYLENELRLSSRFD---HPN--IAKVHEVIYTS--ENIMIVMEYLP
| .....|||.|.  |  . |. |.   .|||.|.||.....|. ..         |.|| ..   ..   |||  | | ... .||   || |.||| .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGDLSNLLT---------RGIIFGTNEQFKFASQIVSALEYLHDRGISHRDIKPENMLFDDEFN------------VKLVDFGLSKE-NC-----SSLQT
 |||....          .. ..  .|  .|  ||.... .||...| ||||||.| |  . .             .|. |||..|  ..       .||
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

YC------GTPVYMAPEIAC----GKEYDGAKADIWAFGITFHAFCFGMLP---YPENDDR----SMLSD-------IKKGNVNIHP--NATGTIKQILD
..      ||| ||||.|      .|.|. .|.||| .|. |.   .|  |   .  ||.     ...         ||. .... .  ..    ... |
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

L
|
L
Kinase 85851.m00046.AA ULK 24-239 26 1.3e-59 204.39 In-house 1-289 (329) Show / Hide 
Range on Protein: 24-239
Range on HMM: 1-289/329
Sequence Identity: 26% (77 aa)

YRVIKVIGKGAFAAVVLALNISTE----EYVAIKIIDRDSIIKQGYLLY-------LENELRLSSRFD--------HPNIAKVHEVIYTS--ENIMIVME
| .....|||.|. |  . |. |.    |.||.|.||....... .. .       |.|| ..  . .        |||| | ... .||   || |.||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YLPNGDLSNLLT----------RGIIFGTNEQFKFASQIVSALEYLHDRGISHRDIKPENMLFDDEFN------------VKLVDFGLSKE-NCS-----
| . |||....           .. ..  .|  .|  ||.... .||...| ||||||.| | .. .             .|. |||..|  ...     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

SLQTYC------GTPVYMAPEIAC----GKEYDGAKADIWAFGITFHAFCFGMLP---YPENDDR-----SMLSD-------IKKGNVNI
 ..|.       ||| ||||.|      .|.|. .|.||| .|. |.   .|  |   .  ||.      . . .       ||| . ..
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQF
Kinase 85851.m00046.AA Ciliate-E2-Unclassified 24-269 25 2.5e-59 203.42 In-house 1-347 (352) Show / Hide 
Range on Protein: 24-269
Range on HMM: 1-347/352
Sequence Identity: 25% (90 aa)

YRVIKVIGKGAFAAVVLALNISTEEYVAIKIIDRDSIIKQGYLLYL---------ENELR-------------LSSRFDHPNIAKVHEVIYTSENIMIVM
|..||.||.|.|. | .. .... .| |.|..    |.|| . ..          .|..              . . ..||.| | ...  . .|| |||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYLPNGDLSNLLTR-----------------GIIFGTNEQF-----KFASQIVSALEYLHDRG-ISHRDIKPENMLFDDE---FNVKLVDFGLSKENCSS
||...|||.. ..                  . ||  ..       ... ||...|||||  . | |||||||| |||..   ...|. |||.||.. ..
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

------------------LQTYCGTPVYM----APEIACGKEYDG---AKADIWAFGITFHAFCFGMLPYPENDDRS----------------MLSDIKK
                  ..| |||| ||    |||. .|..||.    |.|||..|. .....|| .|.. |.. .                ....||.
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

GNV------------NIHPNATGTIKQILDLTLNPDSAKRATAKELL
.|.            ...|.|   |...|   |. .  || |....|
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQIL
Kinase 85851.m00046.AA STE 24-271 21 1.6e-54 187.43 In-house 1-359 (359) Show / Hide 
Range on Protein: 24-271
Range on HMM: 1-359/359
Sequence Identity: 21% (80 aa)

YRVIKVIGKGAFAAVVLALNI------STEEY---------VAIKIIDRDSI--------------IKQGYLLYLENELRLSSRFD--HPNIAKVHEVIY
.. |..||||||  |..|.|.      .| |          .|||... ..               . .  .  ...|... ....  |||| | .   .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TS-------ENIMIVMEYLPNGDLSNLLT-RGIIFGT------------NEQF-KFASQIVSA-LEYLHDRGISHRDIKPENMLFDDEFNVKLVDFGLSK
         ... |.|||...| |. ..  .......             .|  ... ||. . |.|||. .| |||||| | |.     |||.|||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

ENCS-------------------SLQTYCGTPVYMAPEIACG------KEYDGAKADIWAFGITFHAFCFGMLPYPENDDRSMLSDIKKGN---------
   .                     .| .||| .||||.  .      |.|| .|.||| .|.|    . |  |. .  . ...  | ...         
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYD-TKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

----VNIHPNAT----------------------GTIKQILDLTLNPDSAKRATAKELLD-----I
     .. |  .                         |. ... |. |  ||.||..||      |
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 85851.m00046.AA QIK 24-230 35 6.1e-54 185.52 In-house 1-232 (272) Show / Hide 
Range on Protein: 24-230
Range on HMM: 1-232/272
Sequence Identity: 35% (83 aa)

YRVIKVIGKGAFAAVVLALNISTEEYVAIKIIDRDSIIKQGYLLYLENELRLSSRFDHPNIAKVHEVIYTSENIMIVMEYLPNGDLSNLLTR-GI-----
| . . |||| || | || .. | . |||||||. | . . .|  .. |  .  . .||.| |  .|. | . . ||.|| .||..   |.  |      
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDK-SQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------IFGTNEQFKFASQIVSALEYLHDRGISHRDIKPENMLFDDEFNVKLVDFGLS--KENCSSLQTYCGTPVYMAPEIACGKEYDGAK
               .     ...| .||.|| .|.|.|.| |||.| ||.|.| . |.|..|||.|   ..   |.|.||.| | |||.  |||||| |
VNSPDIGDQVLMGVPMAENEARRWF-WQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPK

ADIWAFGITFHAFCFGMLPYPENDD----RSMLS
.|||  |.   .   | ||..   .    ...||
VDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLS
Kinase 85851.m00046.AA MARK 129-269 37 3.2e-38 122.67 In-house 111-257 (262) Show / Hide 
Range on Protein: 129-269
Range on HMM: 111-257/262
Sequence Identity: 37% (55 aa)

SQIVSALEYLHDRGISHRDIKPENMLFDDEF--NVKLVDFGLSKEN--CSSLQTYCGTPVYMAPEIACGKEYDGAKADIWAFGITFHAFCFGMLPYP--E
.|||||..|.|...| |||||||| | |..   |.|. |||.| .    . | | |||| ||||||  .|.||| |.|||. |.   .   | .|.    
RQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDT

NDDRSMLSDIKKGNVNIHPNATGTIKQILDLTLNPDSAKRATAKELL
.|.  .   | .|.  | ..    ..... . |...  .|.|..|..
QDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIM
Kinase 85851.m00046.AA MARK 24-113 33 2.6e-27 86.47 In-house 1-93 (262) Show / Hide 
Range on Protein: 24-113
Range on HMM: 1-93/262
Sequence Identity: 33% (31 aa)

YRVIKVIGKGAFAAVVLALNISTEEYVAIKIIDRDSIIKQGYLLYLENELRLSSRFDHPNIAKVHEVIY--TSEN-IMIVMEYLPNGDLSNLL
|...|.||.|..| | ||... |.. |||||... .. .   .  .. |... .. ||||| | ..||   |... | ..||| ..|.| . .
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYI
Kinase 85851.m00046.AA TyrKc 24-272 25 1e-21 79.41 SMART 1-280 (280) Show / Hide 
Range on Protein: 24-272
Range on HMM: 1-280/280
Sequence Identity: 25% (73 aa)

YRVIKVIGKGAFAAVVLALNISTEEYVAIKIIDRDSIIKQGYLLYLENELRLSSRF--DHPNIAKVHEVIYTS-------ENIMIVMEYLPNGDLSNLLT
 . .|..| |||  |...  .   . ||.| .  |.      .  . .|.|. ...  .|||| . . |. ..       | .|||||| |.||| . | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RGII-FGTNEQFKFASQIVSALEYLHDRGISHRDIKPENMLFDDEFNVKLVDFGLSKENCSS------LQTYC-----GTP--V---YMAPEIACGKEYD
.    . . .  .|. || .  ||||.... |||.   | | .... ||  |||||..  .        ..|      |.   .    ||||    ... 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

GAKADIWAFGITFH-AFCFGMLPYPE-----NDDRSMLSDIKKGNVNIHPNA---------TGTIKQILDLTLNPDSAKRATAKELLDII
  | |.|.||..    | .|. |||.      ... .. ..|.|.    |           .  . ||     . | ..| | .|. ...
-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 85851.m00046.AA Pkinase_Tyr 24-148 26 1.2e-20 70.61 Pfam 1-137 (270) Show / Hide 
Range on Protein: 24-148
Range on HMM: 1-137/270
Sequence Identity: 26% (36 aa)

YRVIKVIGKGAFAAVVLALNI----STEEYVAIKIIDRDSIIKQG-YLLYLENELRLSSRF-DHPNIAKVHEVIY-TSEN--IMIVMEYLPNGDLSNLLT
 . .|..|.|||  |...       .|.  ||.|.. ...  ..  ..  . .|... . . .|||| . . |..  .|   |.||||| |.||| . | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

R----GIIFGTNEQFKFASQIVSALEYLHDRGISHRDI
.    .  . . .  ... || ...|||..... |||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL
Kinase 85851.m00046.AA Pkinase_Tyr 200-272 23 0.002298 12.02 Pfam 194-270 (270) Show / Hide 
Range on Protein: 200-272
Range on HMM: 194-270/270
Sequence Identity: 23% (18 aa)

KADIWAFGITFH-AFCFGMLP-YPENDDRSMLSDI-KKGNVN-IHPNATGTIKQILDLTLNPDSAKRATAKELLDII
| |.|.||..    | .|. | ||. ..  ..  | ..|.   . .|..  | ... .  ..| ..| | .|.. ..
KSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL