Gene 89018.m00092 (T.vaginalis)

89018.m00092

Species: T.vaginalis
Alias: 89018.m00092, TvagK0543
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag2

Sequence

Name Sequence Type Origin Length Description Download
89018.m00092.AA Protein None 336 None Fasta, JSON
89018.m00092.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of 89018.m00092.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 89018.m00092.AA CAMKL 21-266 32 6.5e-85 270.91 In-house 1-291 (297) Show / Hide 
Range on Protein: 21-266
Range on HMM: 1-291/297
Sequence Identity: 32% (97 aa)

YRYLTTLGKGMFACVVLVENIRT-NEKFACKIISREKMEKDNLIIR------------LEEELRILEHIK---HPAIVDIYRIIYQEKL------IMIIM
|| . ||||| |. | | ..||| .|| | ||| ..|. .|  . .            .. | .|.....   || |. .| .|. ..       | ..|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EFCSGGE--MLQKVTQGPT----IRESEICRYAMQILSAINYLHQRDIMHRDIKLENIMIDQNGD--AKLIDFGLSEAFG------EQNLKTHCGTLLYM
| |||||  ..... . .     . |.| .||  ||.||.||.|...| |||||.|||..|.||.  .|.||||.|  .       .| |||.||.. ||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEIICQ-HE-FDGKAVDIWAFGIVIYVMVTRCFPWKSTT-------DEGVIDEIIDTEIFFPN---FISPVISAILHRSLAKDPSKRATAQEL
||||.   .. .||..||||. |.. |.||.  .|..  |       .     ..| .  ..|.   ..|     .... | ..|.||.|....
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQI
Kinase 89018.m00092.AA CAMK 26-265 19 2.1e-79 255.38 In-house 1-418 (425) Show / Hide 
Range on Protein: 26-265
Range on HMM: 1-418/425
Sequence Identity: 19% (83 aa)

TLGKGMFACVVLVENIRTN------------EKFACKIISREKMEK-------------------------DNLIIRLEEELRILEH-------IKHPAI
|||.| |. | |.....|.            .|.|.|||...|. .                         ..   ... |..|. .       ..|| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VDIYRIIYQ-------------------EKLIMIIM---EFCSGGEM----LQKVTQG---------------PTIRESEICRYAMQILSAINYLHQRDI
. .| ..                     .| . ..|   |.|||||.    ......                  . |.| .||  ||.||..|.|...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

MHRDIKLENIMIDQN-----------------GDAKLIDFGLSEAFGE-------------------------QNLKTHCGTLLYMA-PEIICQ------
.|||.|.|||..|.|                 .. |.||||..  | .                         | .|| |||. ||| ||.. .      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------HEFDGKAVDIWAFGIVIYVMVTRCFPWKSTTDEGVID-------------EIIDTEIFFPNF------------------------ISPVISA
       .. .|...|.|. |.. |.|.. ..|. . .|.  ..              |.  .  || .                        .|.    
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

ILHRSLAKDPSKRATAQE
 . . | .||.||.|...
LIRKMLQVDPEKRMTIEQ
Kinase 89018.m00092.AA S_TKc 21-274 27 3.2e-77 263.77 SMART 1-231 (231) Show / Hide 
Range on Protein: 21-274
Range on HMM: 1-231/231
Sequence Identity: 27% (73 aa)

YRYLTTLGKGMFACVVLVENIRTNEKFACKIISREKMEKDNLIIRLEEELRILEHIKHPAIVDIYRIIYQEKLIMIIMEFCSG--GEMLQKVTQGPT---
|. | ..||| |..| .. ...|....|.|||.          .... |..||.. .|| || .| ...  . . ..||.|.|  |....   . ..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---IRESEICRYAMQILSAINYLHQRDIMHRDIKLENIMIDQNGDAKLIDFGLSEAFGEQNLKTHCGTLLYMAPEIICQHEFDGKAVDIWAFGIVIYVMV
   . | ....|. ||..|..|.|.. |.|||.| |||..|.    |..||||.  .     .| |||. |||||..    ......|.|..|...| |.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

TRCFPWKSTTDEGVIDEIIDTEIFFPNFISPVISAILHRSLAKDPSKRATAQELIT-----LISSYS
... |.   ... ... |           ||    .. . | |||.|| || |. .      .  . 
CGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 89018.m00092.AA Pkinase 21-270 26 7.7e-77 266.38 Pfam 1-293 (293) Show / Hide 
Range on Protein: 21-270
Range on HMM: 1-293/293
Sequence Identity: 26% (78 aa)

YRYLTTLGKGMFACVVLVENIRTNEKFACKIISREKMEKDNLIIRLE-EELRILEHIKHPAIVDIYRIIYQEKLIMIIMEFCSGG----EMLQKVT--QG
|. . ..|.| |.|| .  .. |....|.|||.... ... .....   |..|. ...|| || .|.. . .. | ..||.| ||    .    ..  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

PTI--RESEICRYAMQILSAINYLHQRDIMHRDIKLENIMIDQNGDA----KLIDFGLSE---AFGEQNLKTHCGTLLYMAPEIICQHEFDGKAVDIWAF
 ..   | |...|. |||....|.|.. |.|||.|.|||.||.||.     |..||||..       . ..| |||. |||||.|  .. .|..||.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GIVIYVMVTRCFPWKST------TDEGVIDEIIDTEIFFPNFIS---------------------PVISAILHRSLAKDPSKRATAQELITL--I
|...| |... .|...       ..  .|..| .... |. . .                     .    .. . |.|||.|| ||...     .
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 89018.m00092.AA MARK 21-266 36 5.4e-75 244.6 In-house 1-256 (262) Show / Hide 
Range on Protein: 21-266
Range on HMM: 1-256/262
Sequence Identity: 36% (93 aa)

YRYLTTLGKGMFACVVLVENIRTNEKFACKIISREKMEKDNLIIRLEEELRILEHIKHPAIVDIYRIIY--QEKL-IMIIMEFCSGGEMLQKVTQG--PT
|. |.|.|.| .| | |. ...|..|.| ||. ..|. . . .  .. |..|. ...|| |.  . .|    |.  | .||| .||||... . .     
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

IRESEICRYAMQILSAINYLHQRDIMHRDIKLENIMIDQNG--DAKLIDFGLSEAF-GEQNLKTHCGTLLYMAPEIICQHEFDGKAVDIWAFGIVIYVMV
. |.|  |.  ||.||.||.|...| |||||.|||.||.||  ..|.||||.|  .  .| |.|.|||. ||||||. . . ||..||||. |.| |.||
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

TRCFPWKSTT--DEGVIDEIIDTEIFFPNFISPVISAILHRSLAKDPSKRATAQEL
. .||.. .|  ..    .|   .  .| ..|. .  ...| |  .|..|.|..|.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEI
Kinase 89018.m00092.AA AGC 21-260 20 7.9e-70 178.8 In-house 1-373 (395) Show / Hide 
Range on Protein: 21-260
Range on HMM: 1-373/395
Sequence Identity: 20% (79 aa)

YRYLTTLGKGMFACVVLVENI------RTNEKFACKIISREK-MEKDN--LIIRLEEE------------LRILEHIK----------HPAIVD-IYRII
.. |...||| |  | ||.         |.. .|.|... .. . ...   . .   |             .|||...          || ||   .   
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

YQEKL--IMIIMEFCS---------GG-EMLQKVT---QGPTIRESEICRYAMQ-------ILSAINYLHQ-RDIMHRD-IKLENIMIDQNGDAKLIDFG
  ..   . ..||...         || |...      .  .  |.... || .       |..|. |||. ..| ||| .|.|||..|..|  || |||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSEAF----------------------------------------------------GEQNLKTHCG--TLLYMAPEIICQHEFDGKAVDIWA--FGIVI
|.  .                                                    ...  .| ||  |  ||||||.      |||.|.|.  .|...
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCLM

YVMVTRCFPWKSTT---------DEGVIDEIID-------TEIFFP----------NFISPVISAILHRSLAKDPSKR
| |.| . |  . .         ..  . . |         .. ||           ..||    .. . | |||.||
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKR
Kinase 89018.m00092.AA Ciliate-E2 21-272 21 2.7e-67 229.9 In-house 1-365 (365) Show / Hide 
Range on Protein: 21-272
Range on HMM: 1-365/365
Sequence Identity: 21% (81 aa)

YRYLTTLGKGMFACVVLVENIRTNEKFA-----------------------CKIISREKMEKDNLIIRLE----------EELRILEHIKHPAIVDIYRI
|  .  .|.| |..| ..........||                        ||..  . |  . .|..           .|..|||...|| |. .|  
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

IY--QEKLIMIIMEFCSGGEMLQKVTQGPTIR-----------ESEICRYAMQILS---------------AINYLHQRD-IMHRDIKLENIMIDQNGDA
 .  ... | ..||.|.||....   . .. |           | ||...  |||.               |..|||..  |.|||||.|||..      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLIDFGLSEAFGEQNLKTH---------------------------------CGTLLYMAPEIIC--------QHEFDGKAVDIWAFGIVIYVMVTRCFP
|.||||||  . ..| ..                                  |||. ||||||.         ...  ....|||..|...| |..  .|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

WKSTTDEGVIDEIIDTEIFFPNF------------------ISPVISAILHR----SLAKDPSKRAT-AQELITLISS
.        ...|.. .| ||..                  .|.    .. .     | |||.|| | .....     
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 89018.m00092.AA Ciliate-E2-Unclassified 21-267 24 7.4e-66 225.1 In-house 1-347 (352) Show / Hide 
Range on Protein: 21-267
Range on HMM: 1-347/352
Sequence Identity: 24% (84 aa)

YRYLTTLGKGMFACVVLVENIRTNEKF-----ACKIISRE---KMEKDNLIIRLEEELR----------------ILEHIKHPAIVDIYRIIYQEKLIMI
|. . ..|.| |..| ..... .. ..     ..||...    .|.||  |.. ..|.                 || ...|| ||  . .  ... | |
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

IMEFCSGGEMLQKVTQGPT-----------------IRESEIC-----RYAMQILSAINYLHQRD-IMHRDIKLENIMIDQNG---DAKLIDFGLSEAFG
.||.| ||...|  .. ..                 . | ...     .|. |||....|||.   | |||||.|||..|.||     |.||||.|   .
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

-----------------EQNLKTHCGTLLYM----APEIICQHEFDG---KAVDIWAFGIVIYVMVTRCFPWKSTTDEG----------------VIDEI
                 .|...| |||. ||    |||...... |.   ...|||..|...| |..  .| .....|                 ....|
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

IDTEIFFPNFIS----PVIS--------AILHRSLAKDPSKRATAQELI
.. .|.||.|        .|         .|.. | |.|.|| |.....
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQIL
Kinase 89018.m00092.AA AMPK 21-266 34 1.4e-62 184.65 In-house 1-248 (254) Show / Hide 
Range on Protein: 21-266
Range on HMM: 1-248/254
Sequence Identity: 34% (85 aa)

YRYLTTLGKGMFACVVLVENIRTNEKFACKIISREKMEKDNLIIRLEEELRILEHIKHPAIVDIYRII-YQEKLIMIIMEFCSGGEMLQKVTQGPTIRES
|    |.|.| |  | . . |.|.|| | ||. ..|. ..    |.. |..||  ..|| |.  |..|   .. | ..||. ||||    ...   . | 
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EICRYAMQILSAINYLHQRDIMHRDIKLENIMIDQNGDAKLIDFGLSEAFGE-QNLKTHCGTLLYMAPEIICQHEFDGKAVDIWAFGIVIYVMVTRCFPW
| ||.  ||.|.. |.|.  | ||| |.||. .|.|   |. |||||    . . ||| ||   | |||.|      |  ||||  |.. |.|. .  | 
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

KSTTDEGVIDEIIDTEIFFPNFISPVISAILHRSLAKDPSKRATAQEL
         . |.. |   | |.|| .. .... | .|| ||.| ...
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDI
Kinase 89018.m00092.AA ULK 21-262 26 2e-56 193.76 In-house 1-319 (329) Show / Hide 
Range on Protein: 21-262
Range on HMM: 1-319/329
Sequence Identity: 26% (86 aa)

YRYLTTLGKGMFACVVLVENIRT----NEKFACKIISREKMEKDN-------LIIRLEEELRILEHIK--------HPAIVDIYRIIYQE--KLIMIIME
|     |||| |. |   .|..|    |||.|||.|...|| ..|       ..  |. | .|.  .|        || ||  | . .    . | ||||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FCSGGEMLQKVTQGPT----------IRESEICRYAMQILSAINYLHQRDIMHRDIKLENIMIDQN------------GDAKLIDFGLSEAFGEQN----
.| ||   |   .  .          . |.|.  . .|||..  .||.. |.|||||..||.|. .            | .|. |||..  . . |    
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-LKTHC------GTLLYMAPEIICQH----EFDGKAVDIWAFGIVIYVMVTRCFP---W-KSTTDEGVIDE----------IIDTEIFFP-----NFISP
 ..|        || |||||.|. ..    ... . .||| .|...| |..   |   |  .. . .....          | .. . ||     . |||
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

VISAILHRSLAKDPSKRAT
 .  .. | | .|...| .
ECKDLIRRMLQYDEKDRIS
Kinase 89018.m00092.AA ULK 21-262 26 1.8e-55 190.61 In-house 1-314 (324) Show / Hide 
Range on Protein: 21-262
Range on HMM: 1-314/324
Sequence Identity: 26% (84 aa)

YRYLTTLGKGMFA-CVVLVENIRT---NEKFACKIISREKMEKDN----------LIIRLEEELRILEHIKHPA--IVDIYRIIYQE--KLIMIIMEFCS
|     |||| |.  |   .|..|   |...|||.|.. || |..          |...  .....| ..|||   ||  | . .    . | ||||.| 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GG---EMLQKVTQGP------TIRESEICRYAMQILSAINYLHQRDIMHRDIKLENIMIDQN------------GDAKLIDFGLSEAFGE-----QNLKT
||   . ..|    |      .. |.|.  . .||...  .||.. |.|||||..||.|  .            | .|. |||..  . .     | ..|
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

HC------GTLLYMAPEIICQH----EFDGKAVDIWAFGIVIYVMVTRCFP---W-KSTTDEGVIDE----------IIDTEIFFP-----NFISPVISA
 .      || |||||.|. ..    ... . .||| .|...| |..   |   |  .. .  ....          | .. | ||     . ||| .  
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

ILHRSLAKDPSKRAT
.. | | .|...| .
LIRRMLQYDEKDRIS
Kinase 89018.m00092.AA QIK 21-267 32 4.1e-55 189.43 In-house 1-267 (272) Show / Hide 
Range on Protein: 21-267
Range on HMM: 1-267/272
Sequence Identity: 32% (87 aa)

YRYLTTLGKGMFACVVLVENIRTNEKFACKIISREKMEKDNLIIRLEEELRILEHIKHPAIVDIYRIIYQEKLIMIIMEFCSGGEMLQKVTQ-GP-----
|    |.||| || | |  .. | .| | ||| .......||. ... |  |.  ..|| |.  | ..  .. . |..|.||.|||   ... |      
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQ-KCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

--------------TIRESEICRYAMQILSAINYLHQRDIMHRDIKLENIMIDQNGDAKLIDFGLSEAFGEQN-LKTHCGTLLYMAPEIICQHEFDGKAV
               . |.|  |   ||.||. |.|.| | |||.| |||..|.| . |..|||.|  | .   |.| ||.  | |||.    |.||  |
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKV

DIWAFGIVIYVMVTRCFPWKSTTDEGVIDEIIDTEIFFPNFISPVISAILHRSLAKDPSKRATAQELI
|||  |.| ||.|.  .|  . |..   . ..      | |.|     .  . |  ||..| | .  .
DIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQIC
Kinase 89018.m00092.AA TyrKc 21-270 20 5.5e-17 51.95 SMART 1-280 (280) Show / Hide 
Range on Protein: 21-270
Range on HMM: 1-280/280
Sequence Identity: 20% (60 aa)

YRYLTTLGKGMFACVVLVENIRTNEKFACKIISREKMEKDNLIIRLEEELRILEHI--KHPAIVDIYRIIYQE-------KLIMIIMEFCSGGEMLQKV-
 . . .|| | |  |.. . .   .. | | .  ..      .  . .|.||. ..  .|| || .| .. |.       . .||.||....|  ..   
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

TQGPTIRESEICRYAMQILSAINYLHQRDIMHRDIKLENIMIDQNGDAKLIDFGLSEAFGEQ-------NLKTH----CGT----LLYMAPEIICQHEFD
  .|..  .. . .. || .  .|||.. . |||.   |.... |. .|  ||||| . ..          ...    .|     .  |||| |  ..| 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

GKAVDIWAFGIVIYVMVTRCF-PWKS-----TTDEGVIDEIIDT-EIFFPNF--------ISPVISAILHRSLAKDPSKRATAQELITLI
  . |.|.||.... . |..  |.        ... ||  . .      |           .. .  |  .  . ||..| | .|.. ..
-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 89018.m00092.AA Pkinase_Tyr 50-215 25 4.7e-14 48.22 Pfam 34-211 (270) Show / Hide 
Range on Protein: 50-215
Range on HMM: 34-211/270
Sequence Identity: 25% (45 aa)

KIISREKMEKDNLIIRLEEELRILEHI-KHPAIVDIYRIIY-QEKL--IMIIMEFCSGGEMLQKVTQ----GPTIRESEICRYAMQILSAINYLHQRDIM
|..    |...|..  . .|..|. .. .|| ||  | ... |..   |.|.||.. .| .|    .    .. .  .... ...|| .. .||... . 
KMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCI

HRDIKLENIMIDQNGDAKLIDFGLSEAF-GEQNL-KTHCGTLL---YMAPEIICQHEFDGKAVDIWAFGIVIYVMVTRC
|||.   |.... |. .|  ||||. .   . .  ... |. |    |||| |   .|  |  |.|.||.... ..|..
HRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKS-DVWSFGVLMWEIFTYG