Gene 91023.m00093 (T.vaginalis)

91023.m00093

Species: T.vaginalis
Alias: TvagK0087, 91023.m00093
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
91023.m00093.AA Protein None 388 None Fasta, JSON
91023.m00093.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of 91023.m00093.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 91023.m00093.AA CAMKL 9-262 34 1.4e-111 357.43 In-house 1-297 (297) Show / Hide 
Range on Protein: 9-262
Range on HMM: 1-297/297
Sequence Identity: 34% (102 aa)

YSVQFNIGSGTFAQVFLAIH-NKTGTKVAIKVIS--KLNCIDNERNQLL---------MRREIDIMKKLK---HPFVCDLYEVVETEKN------VYIVM
| .   .| |.|..| ||.|   ||.|||||.|   |...... ..  .          |||| |||.|.   || .. ||||.||...      .|.||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EFAQNGT--LLETIKSR----GSLGEEDASIIFAQLLIVMKYLHNECKIAHRDIKAENIVFDSNR--NIRIIDFGLSNSPDS-----NNIMQTQCGSVSY
| ...|   |.. |...    |.. |..|  .| |..  ..|.|. . |.|||||.||| .|.|   || |||||.||  .      .. . |.||| .|
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHG-IVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

ASPEMIMG--QKYT-YASDVWSLGILLYGMVCGHLPFQDTNYS---------RLAQKIVFKEVDYPSQLSSECIDLLKRILKKNQADRIPLNEIEKHPWI
..||.. |  ..|  .. |.||.|..|| ||||.||| | .|.         .. ...  .. . ....| .|.||....|..|  .|. . .|..||| 
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 91023.m00093.AA CAMK 14-262 23 2.3e-103 334.0 In-house 1-425 (425) Show / Hide 
Range on Protein: 14-262
Range on HMM: 1-425/425
Sequence Identity: 23% (102 aa)

NIGSGTFAQVFLAIHNKTG------------TKVAIKVISKLNCID------------------------NERNQLLMRREIDIMKK-------LKHPFV
 .|.|.|..|.|.|| .|.            .|||||.|.|    |                        .....  .||||.||||       |.|| .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

CDLYEVVET-------------------EKNVYIVM---EFAQNG----TLLETIKSRGS---------------LGEEDASIIFAQLLIVMKYLHNECK
. |||| |.                   .|..|.||   |....|     |.. |...|.               . |..|. .| |..  ..|.|.   
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN-

IAHRDIKAENIVFDSN-----------------RNIRIIDFGLSNSPDS------------------------NNIMQTQCGSVSYAS-PEMIMG-----
|.|||.| ||| .|.|                  || |||||..|  |.                        .  |.|.||. .|.. ||.. |     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------QKYTYASDVWSLGILLYGMVCGHLPFQDT-------------NYSRLAQKIVFKEVDYPSQ------------------------LSSECI
         . |....|.||.|..|| |.||..||..              |...| .||   . |.|.                         .| ||.
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLLKRILKKNQADRIPLNEIEKHPWI
||....|...  .|. . .. .|||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 91023.m00093.AA MARK 9-262 42 4.7e-103 337.66 In-house 1-262 (262) Show / Hide 
Range on Protein: 9-262
Range on HMM: 1-262/262
Sequence Identity: 42% (111 aa)

YSVQFNIGSGTFAQVFLAIHNKTGTKVAIKVISKLNCIDNERNQLLMRREIDIMKKLKHPFVCDLYEVVE--TEKN-VYIVMEFAQNGTLLETIKSR--G
| .   || |..|.| ||.| .||.|||||.. | .  |..  . .| |||.|||||.|| .  |..|.|  ||.. .|..|| | .| |.. ||..  |
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVM-REIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNG

SLGEEDASIIFAQLLIVMKYLHNECKIAHRDIKAENIVFDSNR--NIRIIDFGLSNSPDSNNIMQTQCGSVSYASPEMIMGQKYT-YASDVWSLGILLYG
 | ||.|  || |..  ..|.|.   |.|||||.|||  |.|.  || |||||.|.   ...   | ||. .|..||.. ...|. .. |.||||..|| 
RLHEEEARRIFRQIVSAVNYCHSKN-IVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYF

MVCGHLPFQDTN--YSRLAQKIVFKEVDYPSQLSSECIDLLKRILKKNQADRIPLNEIEKHPWI
||||..|| ...  |  | .||.  . |.|. .| || .|..|.|. |  .|. . ||.||||.
MVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 91023.m00093.AA AMPK 9-262 41 7.7e-98 291.05 In-house 1-254 (254) Show / Hide 
Range on Protein: 9-262
Range on HMM: 1-254/254
Sequence Identity: 41% (106 aa)

YSVQFNIGSGTFAQVFLAIHNKTGTKVAIKVISKLNCIDNERNQLLMRREIDIMKKLKHPFVCDLYEVV-ETEKNVYIVMEFAQNGTLLETIKSRGSLGE
| .. .|| |||  | ...|  ||.|||||.. |   | ..  .   .|||.|.|...|| .  ||||. ||..  ..|||....| | . | ..| | |
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNK-QKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQE

EDASIIFAQLLIVMKYLHNECKIAHRDIKAENIVFDSNRNIRIIDFGLSNSPDSNNIMQTQCGSVSYASPEMIMGQKYT-YASDVWSLGILLYGMVCGHL
..|.  |.| .    |.|.  .|.||| | ||. .| | || | ||||||    ..   | |||  ||.|||| |..|     |.|| |. || |.|| |
REACRFFQQIISGVEYCHR-HMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYL

PFQDTNYSRLAQKIVFKEVDYPSQLSSECIDLLKRILKKNQADRIPLNEIEKHPWI
|| | | . | .||.  |.  |. ||.|. ||.|..|...   ||  ..| .||| 
PFDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 91023.m00093.AA S_TKc 9-262 32 2.3e-92 314.06 SMART 1-231 (231) Show / Hide 
Range on Protein: 9-262
Range on HMM: 1-231/231
Sequence Identity: 32% (87 aa)

YSVQFNIGSGTFAQVFLAIHNKTGTKVAIKVISKLNCIDNERNQLLMRREIDIMKKLKHPFVCDLYEVVETEKNVYIVMEFAQN--GTLLETIKSRGS--
| .   ||.|.|..|....|.||| .||||.|.             .||||.|.|| .||... ||.| .. ...|.|||.. .  |.|.. ||.||.  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LGEEDASIIFAQLLIVMKYLHNECKIAHRDIKAENIVFDSNRNIRIIDFGLSNSPDSNNIMQTQCGSVSYASPEMIMGQKYTY-ASDVWSLGILLY
    . | .|  ...|..  ..|.|.  .| |||.| ||| .|.  .| |.||||.          |.||.  | .||..   .|.. ..|.||.|..||
LRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

GMVCGHLPFQDTNYSRLAQKIVFKEVDYPSQLSSECIDLLKRILKKNQADRIPLNEIEK-------HPWI
 |.||  ||.  .. .. .||.          |.|..|.....|.|. ..|.   |. .       |||.
EMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 91023.m00093.AA Pkinase 9-262 30 1.8e-82 285.13 Pfam 1-293 (293) Show / Hide 
Range on Protein: 9-262
Range on HMM: 1-293/293
Sequence Identity: 30% (90 aa)

YSVQFNIGSGTFAQVFLAIHNKTGTKVAIKVISKLNCIDNERNQLLMRREIDIMKKLKHPFVCDLYEVVETEKNVYIVMEFAQNG----TLLETIK--SR
| .   ||||.|..|....| .|| .||.|.|.| .  .... ... ..|| |||.|.||... ||...|.....|.|||....|     | . |.  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GSL--GEEDASIIFAQLLIVMKYLHNECKIAHRDIKAENIVFDSNRNI----RIIDFGLSNS--PDSNNIMQTQCGSVSYASPEMIM-GQKYTYASDVWS
|..   |...  .. |.|  ..|.|. ..| |||.| ||| .|.| .|    .|.||||.      .|  |.| ||.  |..|| |. ||.|....|.||
GCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGILLYGMVCGHLPFQDT------NYSRLAQKIVFKEVDYPSQLS---------------------SECIDLLKRILKKNQADRIPLNEIEKHPWI
.|..|| |.||..||..       .   . ..|  ........ .                     .||.|..|..|.|. ..|.   .| .|||.
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 91023.m00093.AA Ciliate-E2-Unclassified 9-262 27 3.5e-81 276.02 In-house 1-352 (352) Show / Hide 
Range on Protein: 9-262
Range on HMM: 1-352/352
Sequence Identity: 27% (96 aa)

YSVQFNIGSGTFAQVFLAIHNKTGTKV-----AIKVISKLNCIDNERNQLLMRREIDIMKK------------------LKHPFVCDLYEVVETEKNVYI
| ..  ||.| |..|....|.|.. ..     ..|....  .. .. .  .|. .. ...|                  ..|||.  .... ....|.||
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VMEFAQNGTLLETIKSRGS-----------------LGEEDAS-----IIFAQLLIVMKYLHNECKIAHRDIKAENIVFDSNR---NIRIIDFGLSNSPD
|||....|.|.. ||.|..                 . |. |.      .|||.|   .||| . .| ||||| |||.||.|    .|.|||||.|  ..
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

SN----------------NIMQTQCGSVSYA----SPEMIMGQKYT----YASDVWSLGILLYGMVCGHLPFQDTNYSR----------------LAQKI
.|                ..|.|.||. .|     .||...||.|     |..|.||||..|| |. | .||.|.|.                  | |.|
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

VFKEVDYPS--------QLSSECIDLLK----RILKKNQADRIPLNEIEKHPWI
  |....|.        ..| |..|...    ..||||.  || ...| .|||.
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 91023.m00093.AA Ciliate-E2 9-262 25 1e-80 274.47 In-house 1-365 (365) Show / Hide 
Range on Protein: 9-262
Range on HMM: 1-365/365
Sequence Identity: 25% (97 aa)

YSVQFNIGSGTFAQVFLAIHNKTGTKVAIK--------------VISKLNCIDNERNQ--LLMRREIDIMK----------------KLKHPFVCDLYEV
| ..  ||.|.|..|... . |.. ..|||              | .|.  . . ...    . .||.||.                .|.||... .||.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VE--TEKNVYIVMEFAQNGTLLETIKSR-----------GSLGEEDASIIFAQLL---------------IVMKYLHNECKIAHRDIKAENIVFDSNRNI
 .  ...|.|.|||..| |.|.. ||..           ... |. .. |..|.|                 ..|||.. .| ||||| |||.|     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

RIIDFGLSNSPDSN--------------------------------NIMQTQCGSVSYASPEMIMGQK---------YTYASDVWSLGILLYGMVCGHLP
 |||||||   | .                                |. .|.||.  | .||...|.|         |.|..|.||||..|| |..| .|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FQDTNYSRLAQKIVFKEVDYP------------------SQLSSECIDLLKR----ILKKNQADRIP-LNEIEKHPWI
|         |.|  ...|.|                   ..| ||.||.|.    .|.|..  ||   ..| .|||.
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 91023.m00093.AA QIK 9-262 36 8.9e-79 268.02 In-house 1-272 (272) Show / Hide 
Range on Protein: 9-262
Range on HMM: 1-272/272
Sequence Identity: 36% (101 aa)

YSVQFNIGSGTFAQVFLAIHNKTGTKVAIKVISKLNCIDNERNQLLMRREIDIMKKLKHPFVCDLYEVVETEKNVYIVMEFAQNGTLLETIKSRGS----
| .   || | || | || |  | ||||||.| |  ..| | |   . ||. ||| |.||..  ||.| ||..  |||.|...|| . ... . |     
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDK-SQLD-EENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVK

----------------LGEEDASIIFAQLLIVMKYLHNECKIAHRDIKAENIVFDSNRNIRIIDFGLSNSPDSNNIMQTQCGSVSYASPEMIMGQKYT-Y
                . |..|  .| |..   .|.|.  .|.|||.||||| .|.| || |.|||.||   .   ..| |||  || |||  |..|.  
MVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKR-NIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGP

ASDVWSLGILLYGMVCGHLPFQDTNYSRLAQKIVFKEVDYPSQLSSECIDLLKRILKKNQADRIPLNEIEKHPWI
 .|.||.|..|| .||| |||   .   | |...   .  |  .|..| .| .. |  . . |.  . | .|.|.
KVDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase 91023.m00093.AA AktR 9-262 32 4.3e-74 252.46 In-house 1-268 (268) Show / Hide 
Range on Protein: 9-262
Range on HMM: 1-268/268
Sequence Identity: 32% (87 aa)

YSVQFNIGSGTFAQVFLAIHN-KTGTKVAIKVISKLNCIDNERNQLLMRREIDIMK-KLKHPFVCDLYEVVETEKNVYIVMEFAQNGTLLETIKSRGSLG
. |  ..|.|.|..|.|. .. ... ..|.|.|.| . |......  ...| .||. . .|||   |..  .|... ...||. ..| |.  .|... . 
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMH-HTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFS

EEDASIIFAQLLIVMKYLHNECKIAHRDIKAENIVFDSNRNIRIIDFGLSN-SPD--SNNIMQTQCGSVSYASPEMIMG-QKYTYASDVWSLGILLYGMV
||.| ..||| |.   |||.. .|  ||.| |||. |.. ...|.|||||.  ..   . . .. ||.. | .||||.  . .....| |..||..| ||
EEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMV

CGHLPFQDTNYSRLAQKIVFKE---VDYPSQLSSECIDLLK-RILKKNQADRIP-----LNEIEKHPWI
 |. ||.. |  .. ||| .|.   ..|||..||.| ||.. ..|.||.  |.        || .||| 
TGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 91023.m00093.AA ULK 9-262 29 5.3e-74 252.15 In-house 1-329 (329) Show / Hide 
Range on Protein: 9-262
Range on HMM: 1-329/329
Sequence Identity: 29% (96 aa)

YSVQFNIGSGTFAQVFLAIHNKT----GTKVAIKVISKLNCIDNERNQL------LMRREIDIMKKLK--------HPFVCDLYEVVETE--KNVYIVME
|..   .|.|.|..|. ....||    . |||.|.|.|  .. .. .|       | ..||.||||||        || .. ||.. ||   .|.||.||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FAQNGTLLETIKSRGSLGEED----------ASIIFAQLLIVMKYLHNECKIAHRDIKAENIVFDSNRN------------IRIIDFGLSNSPDSN----
. . |.| . || .. |.|.           | ..| |.|  .|.|| . .| ||||| .||  . .              . | |||.. . |..    
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKH-NIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQ

NIMQTQC------GSVSYASPEMIM----GQKYT-YASDVWSLGILLYGMVCGHLP----FQDTN---YSRLAQK-------IVFKEVDYP-----SQLS
..|.|.       |.  | .|. ..    ...|. | .|.||||...| |. |  |    |.|..   . .| ..       |  .  ..|      |.|
QMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

SECIDLLKRILKKNQADRIPLNEIEKHPWI
.||.||..| |.... |||   |. .|||.
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 91023.m00093.AA TSSK 57-262 38 1.4e-70 230.89 In-house 64-289 (289) Show / Hide 
Range on Protein: 57-262
Range on HMM: 64-289/289
Sequence Identity: 38% (88 aa)

REIDIMKK-LKHPFVCDLYEVVETEK-NVYIVMEFAQNGTLLETIKSR------GSLGEEDASIIFAQLLIVMKYLHNECKIAHRDIKAENIVFDSNRNI
|||.||.| ||||... .||  ||.   .|.|||.|..|.||| |. |      | | ||.|   | |.   .||.|. . ..|||.| |||  | ..||
REIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAEHGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHS-HNVVHRDLKCENILLDKHWNI

RIIDFGLSN--SPDS----NNIMQTQCGSVSYASPEMIMGQKY-TYASDVWSLGILLYGMVCGHLPFQD--TNYSRLAQKIVFKEVDYP----SQLSSEC
 ..||| ..  ..|.    ..  .| |||..||.|| ..| .|   ..||||.|. || ||||..|| |  .|  .. . .  ..| .|      .|.||
KLTDFGFARYWPRDDPGRCCHLSKTFCGSYAYAAPEILRGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQEC

IDLLKRILKKNQADRIPLNEIEKHPWI
.||....|  .   |. .||| .|.|.
KDLIRHMLQPHPCNRPHINEICHHCWM
Kinase 91023.m00093.AA Pkinase_Tyr 15-199 28 2.1e-23 79.86 Pfam 7-205 (270) Show / Hide 
Range on Protein: 15-199
Range on HMM: 7-205/270
Sequence Identity: 28% (58 aa)

IGSGTFAQVFLAIHN----KTGTKVAIKVISKLNCIDNERN--QLLMRREIDIMKKL-KHPFVCDLYEVVE-TEKN--VYIVMEFAQNGTLLETIKSRGS
.|.| | .|.... .    .|...||.|.. |      ...  .  . ||. |||.| .|| .  || |.   ..   .|||||....| ||.  ...  
LGEGAFGEVYKGTWKGDPDNTKIPVAVKML-K--EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHR-

LGEEDASIIFAQLLIV-------MKYLHNECKIAHRDIKAENIVFDSNRNIRIIDFGLSN--SPDSNNIMQTQC---GSVSYASPEMIMGQKYTYASDVW
  |.. ..   .||         | ||. . .. |||. | |.  ..|. ..| ||||.    .|..  ....      .   .|| |.  |.| .||||
--EDKQPLTMKDLLQMCWQIAKGMEYLE-SKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVW

SLGILLY
| |.|..
SFGVLMW
Kinase 91023.m00093.AA TyrKc 9-262 21 1.3e-16 45.65 SMART 1-280 (280) Show / Hide 
Range on Protein: 9-262
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

YSVQFNIGSGTFAQVFLAIHNKTGTKVAIKVISKLNCIDNERNQLLMRREIDIMKKL--KHPFVCDLYEVVETE-------KNVYIVMEFAQNGTLLETI
 .    .|.| | .|.... .   ..||.|.. .         .  ..||. ||.||  .|| .  || |. ..       . ..||||.. .| |.. .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

KSRGS-LGEEDASIIFAQLLIVMKYLHNECKIAHRDIKAENIVFDSNRNIRIIDFGLSNSPDSN--------NIMQTQ--CGS----VSYASPEMIMGQK
....  |  .|   .  |    | |||   .. |||. | |.  ..|. ..| |||||   ..          .....  .|     .   .|| |.  |
RKHRPKLCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YTYASDVWSLGILLYGMV-CGHLPFQD-----TNYSRLAQKIVFKEVDYPSQL---------SSECIDLLKRILKKNQADRIPLNEIEKHPWI
.| .||||| |.... .   |  |  .      . ... ...   .   . .          ..|  .. |.  . . .||   .||  |  .
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 91023.m00093.AA TSSK 9-42 30 1.2e-09 27.83 In-house 1-50 (289) Show / Hide 
Range on Protein: 9-42
Range on HMM: 1-50/289
Sequence Identity: 30% (15 aa)

YSVQFNIGSGTFAQVFLAIHNKTGTK----------------VAIKVISK
| |. .||.|..| | .| . |.  |                ||||.|..
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDR