88278.m00137

Species: T.vaginalis
Alias: 88278.m00137, TvagK0069
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
88278.m00137.AA Protein None 396 None Fasta, JSON
88278.m00137.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of 88278.m00137.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 88278.m00137.AA CAMK 19-267 25 4.6e-112 362.51 In-house 1-425 (425) Show / Hide
Range on Protein: 19-267
Range on HMM: 1-425/425
Sequence Identity: 25% (107 aa)

TLGHGAFSVVKLAIHNVTK------------QQFACKIIKKTALSKDN------------------------KAEERFELETRILQQ-------MRHPNI
|||.|.|..|||.||  |.            |..|.|||.|. |....                        | ..... | .|...       ..||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

AQLFDIMADGTF-------------------FYVVL---EICPNGEL----FKFIIQNKF---------------LPENEAKMYMKPIVEALKYIHDLKV
 .|.... |...                   .| |.   | |..|||    | .|....                ..| ||. |.. |..|..|.|....
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDLKPENILLDDK-----------------NRPKITDFGFSRYVLH------------------------DQLLKTTCGSPCYAS-PACIAG------
||||||||||||||.                 |  ||.||||.... .                        .|..|| ||.|.|.. |  . |      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------KEYDGFKNDIWGLGVIFFATVTGQLPWTKK-------------IESELFEQISRAEYT-IPSY---------------ISDD--------LRE
       |.|.|.| |.| .||| .. ..| .|.  .              ..||||.| ...|. .|.|               |||.         . 
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LISSMMNIDESKRPTCDQILASPWF
||..|.. | .||.|..|.|. ||.
LIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 88278.m00137.AA CAMKL 14-267 36 4.8e-110 352.39 In-house 1-297 (297) Show / Hide
Range on Protein: 14-267
Range on HMM: 1-297/297
Sequence Identity: 36% (108 aa)

YTFKQTLGHGAFSVVKLAIH-NVTKQQFACKIIKKTALSKDNKAEER-----------FELETRILQQMR---HPNIAQLFDIMADGTF------FYVVL
|.. .|||.|.|..||||.|   |... | |||.|  ...| ... .            . | .|.....   |||| .|.... . ..      .| |.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EICPNGE--LFKFIIQNKF----LPENEAKMYMKPIVEALKYIHDLKVVHRDLKPENILLDDKN--RPKITDFGFSRYVL-H----DQLLKTTCGSPCYA
| |..||  || .|....     .||.||. | . ||.|..|.|....||||.||||||||...    ||.||||| .   .    .|.||| ||||.|.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

SPACIAG--KEYDGFKNDIWGLGVIFFATVTGQLPWTKK--------IESELFEQISRAEYTIP--SYISDDLRELISSMMNIDESKRPTCDQILASPWF
.|  ..|  |.|||.| ||| .||| .| |.|.||.              .|...| .  | .|  ...| |.| ||..|.. . .||||..||.  ||.
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM





Kinase 88278.m00137.AA MARK 14-267 36 1.8e-107 352.34 In-house 1-262 (262) Show / Hide
Range on Protein: 14-267
Range on HMM: 1-262/262
Sequence Identity: 36% (96 aa)

YTFKQTLGHGAFSVVKLAIHNVTKQQFACKIIKKTALSKDNKAEERFELETRILQQMRHPNIAQLFDIMA--DGTF-FYVVLEICPNGELFKFIIQN--K
| ...|.|||....||||.|  |....| ||..|. |.. ... . .. | .|.... |||| .||...   . .  .|...| ...|||. .|..    
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLND-PQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNG

FLPENEAKMYMKPIVEALKYIHDLKVVHRDLKPENILLDDKN--RPKITDFGFSRYVLHDQLLKTTCGSPCYASPACIAGKEYDGFKNDIWGLGVIFFAT
 |.|.||. . . ||.|..| |.  .||||.||||||.|...    ||.|||||. .  .|.|.| ||.| |..|  . .|.|||.| ||| |||. .. 
RLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM

VTGQLPWTKKI--ESELFEQISRAEYTIPSYISDDLRELISSMMNIDESKRPTCDQILASPWF
|.|..|.  .   . ||...| | .|.||...|...| ||....... ..|||...|.  ||.
VCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase 88278.m00137.AA AMPK 14-267 40 2.6e-106 316.61 In-house 1-254 (254) Show / Hide
Range on Protein: 14-267
Range on HMM: 1-254/254
Sequence Identity: 40% (103 aa)

YTFKQTLGHGAFSVVKLAIHNVTKQQFACKIIKKTALSKDNKAEERFELETRILQQMRHPNIAQLFDIM-ADGTFFYVVLEICPNGELFKFIIQNKFLPE
|  ..|.| |.|  ||...|  |... | ||. |. . || .  || . | .||. .|||.| ||...     | ...|.|  ..|||| .|.... |.|
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKI-KDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQE

NEAKMYMKPIVEALKYIHDLKVVHRDLKPENILLDDKNRPKITDFGFSRYVLHDQLLKTTCGSPCYASPACIAGKEYDGFKNDIWGLGVIFFATVTGQLP
 ||. ... |. .. |.|....|||||||||.|||.... || ||| | .    ..||| |||||||.|  |.|| | | . |||  ||| .| . | ||
REACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLP

WTKKIESELFEQISRAEYTIPSYISDDLRELISSMMNIDESKRPTCDQILASPWF
      ..|.  |   ||.||...|.. ..||..| . |  || | ..| ..|||
FDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF

Kinase 88278.m00137.AA S_TKc 14-267 32 3.3e-92 313.55 SMART 1-231 (231) Show / Hide
Range on Protein: 14-267
Range on HMM: 1-231/231
Sequence Identity: 32% (87 aa)

YTFKQTLGHGAFSVVKLAIHNVTKQQFACKIIKKTALSKDNKAEERFELETRILQQMRHPNIAQLFDIMADGTFFYVVLEICPN--GELFKFIIQNKF--
|.. ...|.|||..|....|. |....|.||||           |... | .||.. .|||| .|.|.. | ...|.|.| |..  |.||..| ...   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LPENEAKMYMKPIVEALKYIHDLKVVHRDLKPENILLDDKNRPKITDFGFSRYVLHDQLLKTTCGSPCYASPACIAGKEYDGFKNDIWGLGVIFFA
    .|| .|. ||. |..||.|.|.....||||||||||||.  . ||.|||..| .      .| ||.| | .|  .    |...| |.| .|.|.. 
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

TVTGQLPWTKKIESELFEQISRAEYTIPSYISDDLRELISSMMNIDESKRPTCDQILA-------SPWF
 ..|. |.    . ..|..|           |......|. ... | .||||. ..|.        |||
MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 88278.m00137.AA Pkinase 14-267 28 4.1e-87 300.52 Pfam 1-293 (293) Show / Hide
Range on Protein: 14-267
Range on HMM: 1-293/293
Sequence Identity: 28% (85 aa)

YTFKQTLGHGAFSVVKLAIHNVTKQQFACKIIKKTALSKDNKAEERFEL--ETRILQQMRHPNIAQLFDIMADGTFFYVVLEICPNG----ELFKFII--
|......| |.|..|....|  | ...|.|||||   ... . ...  .  | .|.. ..|||| .|.|.. |..  |.|.| |..|    .|| .|   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR--HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

QNKFL--PENEAKMYMKPIVEALKYIHDLKVVHRDLKPENILLDDKNRP----KITDFGFSRY--VLHDQLLKTTCGSPCYASPACIAGKEYDGFKNDIW
... .  .|.|.|.||. |...|.|.|. ...||||||||||.|... .    ||.|||...     ... ..| ||.| |..|  | | .|.| | |.|
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

GLGVIFFATVTGQLPWTKK------IESELFEQISRAEYTIPSYIS---------------------DDLRELISSMMNIDESKRPTCDQILASPWF
..|.|..  ..|..|.  .       . .....| ....  ... .                     ......|... . | .||||..||| .|||
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 88278.m00137.AA QIK 14-267 37 2.8e-81 276.36 In-house 1-272 (272) Show / Hide
Range on Protein: 14-267
Range on HMM: 1-272/272
Sequence Identity: 37% (104 aa)

YTFKQTLGHGAFSVVKLAIHNVTKQQFACKIIKKTALSKDNKAEERFELETRILQQMRHPNIAQLFDIMADGTFFYVVLEICPNGELFKFIIQNKF----
|.  .|.| | | ||||| | .||.. | ||| |..| ..|   .. . |  |. ...||.|  |...|      |.| | |.|||.|  ....      
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENL--QKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVK

----------------LPENEAKMYMKPIVEALKYIHDLKVVHRDLKPENILLDDKNRPKITDFGFSRYVLHDQLLKTTCGSPCYASPACIAGKEYDGFK
                ..||||.   . |. | .| |....|||||| ||||||     || ||||| .   .|||.| |||| || |    |||||| |
MVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPK

NDIWGLGVIFFATVTGQLPWTKKIESELFEQISRAEYTIPSYISDDLRELISSMMNIDESKRPTCDQILASPWF
 ||| .||. .. |.| ||   |   .| . .    . || ..| |. .||  |. .| ..| | .||.  .| 
VDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM

Kinase 88278.m00137.AA ULK 14-267 26 7.3e-80 271.64 In-house 1-324 (324) Show / Hide
Range on Protein: 14-267
Range on HMM: 1-324/324
Sequence Identity: 26% (87 aa)

YTFKQTLGHGAFS-VVKLAIHNVT---KQQFACKIIKKTALSKDNKA------EERFELETRILQQMR---HPN--IAQLFDIMADG--TFFYVVLEICP
|  .. ||.|.|  .|  .... |   .|..|||.| |  ..|...        . .. | .|....    |||  | .|.|.  .   ...| ..| |.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGELFKFIIQN---------KFLPENEAKMYMKPIVEALKYIHDLKVVHRDLKPENILLDDKN------------RPKITDFGFSRYVLHD----QLLKT
 | |...| .|         |.|.|.||. ..| |....|..|. ...|||.||.|||. ...            . ||.||||.. |  .    |...|
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

TC------GSPCYASPACIA----GKEYDGFKNDIWGLGVIFFATVTGQLP---WTKKIES----ELFEQ-------ISRAEYTIP-----SYISDDLRE
..      |.| | .|  .     .|.|. .| ||| ||.||.  ..|. |   | .  .     .| ..       |      .|       ||.....
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LISSMMNIDESKRPTCDQILASPWF
||. |. .||..| . ..|.. |||
LIRRMLQYDEKDRISWEEIFNHPWF

Kinase 88278.m00137.AA ULK 14-267 26 8.8e-77 261.39 In-house 1-329 (329) Show / Hide
Range on Protein: 14-267
Range on HMM: 1-329/329
Sequence Identity: 26% (88 aa)

YTFKQTLGHGAFSVVKLAIHNVTK----QQFACKIIKKTALSKDNKAEE------RFELETRILQQMR--------HPNIAQLFDIMADGTF--FYVVLE
|  .. ||.|.| .|  .... ||    ...|||.| |  ....|.  |       .. | .|....         |||| .|.|.  . ..  .| ..|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

ICPNGELFKFIIQN----------KFLPENEAKMYMKPIVEALKYIHDLKVVHRDLKPENILLDDKN------------RPKITDFGFSRYVLHD----Q
 |. | |...| .|          |.|.|.||. ..| |....|..|. ...|||.||.|||.....            . ||.||||.. |  |    |
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

LLKTTC------GSPCYASPACIA----GKEYDGFKNDIWGLGVIFFATVTGQLP---WTKKIES-----ELFEQ-------ISRAEYTIPSY-----IS
...|.       |.| | .|  .     .|.|. .| ||| ||.||.  ..|. |   | .  .      .|...       |      .| .     ||
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

DDLRELISSMMNIDESKRPTCDQILASPWF
.....||. |. .||..| . ..... |||
PECKDLIRRMLQYDEKDRISWEELFNHPWF

Kinase 88278.m00137.AA Ciliate-E2 14-267 24 2.2e-73 250.11 In-house 1-365 (365) Show / Hide
Range on Protein: 14-267
Range on HMM: 1-365/365
Sequence Identity: 24% (92 aa)

YTFKQTLGHGAFSVVKLAIHNVTKQQFA----------------CKIIKKTALSKDNKAEERFELETRILQQMR----------------HPNIAQLFDI
| | . .| |.|..|... .  ...|||                .|| ..   .. ..  | .. | .|.....                |||| .... 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

MA--DGTFFYVVLEICPNGELFKFIIQNKFLP-----------ENEAKMYMKPIVE---------------ALKYIHDLK-VVHRDLKPENILLDDKNRP
    | . .| |.| |  |.||..|..||              |.|.| .|| |..               ||.|.|  . ..|||.||||||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KITDFGFSRYVLHD--------------------------------QLLKTTCGSPCYASPACIAGKEYDG--------FKNDIWGLGVIFFATVTGQLP
||.|||.|...  |                                .. .|.||.| | .|  . ||.||.        .| ||| ||||..  ..|..|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

WTKKIESELFEQISRAEYTIP------------------SYISDDLRELISS----MMNIDESKRPT-CDQILASPWF
.        ..||   .. .|                   ..|..   ||.     |.. |..||.|  .|||  |||
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 88278.m00137.AA RSK 16-267 29 2.3e-73 250.05 In-house 1-278 (278) Show / Hide
Range on Protein: 16-267
Range on HMM: 1-278/278
Sequence Identity: 29% (83 aa)

FKQT--LGHGAFSVVKLAIHNVTKQQFACKIIKKTALSKDNKAEERFELETRILQQMR-HPNIAQLFDIMADGTFFYVVLEICPNGELFKFIIQNKF---
 |.   .| |......  .|  |.|..| |..||  . . .|. ..   | .||.  . ||.| .|..   ... .| ..| |. ||||. . . |.   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LPENEAKMYMKPIVEALKYIHDLKVVHRDLKPENILLDD---KNRPKITDFGFSRY-VLH-DQLLKTTCGSPCYASPACIA----GKEYDGFKNDIWGLG
. |.||..||  || |....|.....||||||||||.||     . |.|||||... ...  |...| |..  |. |  ..    .. .|    |.| ||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHD-KACDWWSLG

VIFFATVTGQLPWTK---KIESELFEQISRAE--YTIP--SYISDDLRELISSMMNIDESKRPT-----CDQILASPWF
|. .   ||..| .    .  .|....| ...   |.|  .|.|.. ..||. |.  |..||..      ..|...|||
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase 88278.m00137.AA Ciliate-E2-Unclassified 14-267 24 9.7e-71 241.32 In-house 1-352 (352) Show / Hide
Range on Protein: 14-267
Range on HMM: 1-352/352
Sequence Identity: 24% (87 aa)

YTFKQTLGHGAFSVVKLAIHNVTKQQF-----ACKIIKKTALSK-DNKAEERFE---LETR--------------ILQQMRHPNIAQLFDIMADGTFFYV
|.. ...|.|.|..|....|. .| |.     ..||...  ...  .. |. .|   .. .              ||... ||.|  .|..  |   .| 
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VLEICPNGELFKFIIQNKF-----------------LPENEAK-----MYMKPIVEALKYIHDLK-VVHRDLKPENILLDDKN---RPKITDFGFSRYVL
|.| |..|.|...| ..|.                 ..|..||      |.. |...|.|.|  . ..|||.||||||.|...   ..||.|||.|..  
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

----------------HDQLLKTTCGSPCYA----SPACIAGKEYDG---FKNDIWGLGVIFFATVTGQLPWT-KKIES---------------ELFEQI
                 .|...|.||.|.|     .| .. |..||.   .| |||.||||... ..|..|   .. |.               .|...|
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

SRAEYTIPS--------YISDDLRELIS----SMMNIDESKRPTCDQILASPWF
   .. .|.         .|.   ..|.    .|.. . .||.| .|||  |||
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 88278.m00137.AA TyrKc 14-267 23 9.2e-16 32.18 SMART 1-280 (280) Show / Hide
Range on Protein: 14-267
Range on HMM: 1-280/280
Sequence Identity: 23% (68 aa)

YTFKQTLGHGAFSVVKLAIHNVTKQQFACKIIKKTALSKDNKAEERFELETRILQQM--RHPNIAQLFDIMADG-------TFFYVVLEICPNGELFKFI
 |....||.||| .| ... .   .| | | .|. |       .| |  | ||. .   .|||| .|. .  ..          ..|.| .|.| | ...
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

IQNK-FLPENEAKMYMKPIVEALKYIHDLKVVHRDLKPENILLDDKNRPKITDFGFSRYVLHD-------QLLKTTC--GSP--C---YASPACIAGKEY
  ..  |.  .   ..  | .   |.|. ...||||   |.|...... ||.||| ||.. .|       .  ...   |.         .| ||  ...
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

DGFKNDIWGLGVIFFATVT-GQLPWTK-----KIESELFEQISRAEY-TIPSY--------ISDDLRELISSMMNIDESKRPTCDQILASPWF
  .| |.|  ||  .   | || |.       .  .|..|.. . ..  .| .         .|.. .....  . | ..|||  .|     |
T-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase 88278.m00137.AA Pkinase_Tyr 14-166 29 2.5e-13 45.74 Pfam 1-164 (270) Show / Hide
Range on Protein: 14-166
Range on HMM: 1-164/270
Sequence Identity: 29% (49 aa)

YTFKQTLGHGAFSVVKLAIHN----VTKQQFACKIIKKTALSKDNKAEERFELETRILQQM-RHPNIAQLFDIMA-DGTF--FYVVLEICPNGELFKFII
 || ..||.||| .|.... .     ||.. | |..| .| ...|   | |  | .|. |. .|||| .|  .   .|     |.|.| .|.| | ..  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQN-CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

Q----NKFLPENEAKMYMKPIVEALKYIHDLKVVHRDLKPENILLDDKNRPKITDFGFSRYVLHD
.    .. |.  .   .   | ... | .. . .||||   |.|....|  ||.||| .|.. .|
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYND