Gene 82569.m00144 (T.vaginalis)

82569.m00144

Species: T.vaginalis
Alias: TvagK0715, 82569.m00144
External Links:
Annotation:

Classification

Group: CMGC
Family: CK2

Sequence

Name Sequence Type Origin Length Description Download
82569.m00144.AA Protein None 372 None Fasta, JSON
82569.m00144.kin_dom Protein Kinase Domain None 285 None Fasta, JSON

Protein domain

Protein domains of 82569.m00144.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 82569.m00144.AA CK2 77-361 44 9.80000000001e-123 368.46 In-house 1-288 (288) Show / Hide 
Range on Protein: 77-361
Range on HMM: 1-288/288
Sequence Identity: 44% (127 aa)

YTLEEWVGDGRYSDVFMGFQDGQKK-C--AIKLLKPVNTDRVRRELKILTIIQGHPCILNLMDIVIDGKEGIPSMITEYVPNSTWRTLFSTMDLEDIRFY
| ... .| |.||.|| |..   .. |   ||.||||   ...||.|||. ..|.| | .|.||| | .  .|... ||| |  .|.|. |..  |||.|
YEVIRKIGRGKYSEVFEGINIKNNEKCKIVIKILKPVKKKKIKREIKILENLNGGPNIIKLYDIVKDPYSKVPALVFEYVNNTDFRQLYQTLTDYDIRYY

TYRILQALSYTHSKGIMHRDVKPLNILCNSPRNKVILADWGLAEFYHPMRKYSVHVATRYYKSPEILLDYEYYDYSLDIWSVGVILLELLTLKLHVFDGG
 . .|.|| |.||.||||||||| ||. .  . |  | ||||||||||  .| | ||.|||| || |.||.|||||||.||.|...  ..  |   | | 
MFELLKALDYCHSMGIMHRDVKPHNIMIDHEKRKLRLIDWGLAEFYHPGQDYNVRVASRYYKGPELLVDYQYYDYSLDMWSLGCMFASMIFKKEPFFHGH

DNEHQIDSIVEVIGGAPILDWARKYRVKIHREERERFSQMKGQSFETLIPFSRRKFRDPEALDLVNKMLTIDHKERITADEALQHPFF
||  |   || |.|   .... .|| ... ..  .   | | ...| .|    ..  .|||.|...||| .||.||||| ||..||.|
DNYDQLVKIVKVLGTEDLYKYLDKYGIHLDPQFHDIMQQHKKKPWERFIHQENKHLAHPEAIDFLDKMLRYDHQERITAKEAMEHPYF
Kinase 82569.m00144.AA CMGC 77-361 19 8.4e-80 261.73 In-house 1-513 (513) Show / Hide 
Range on Protein: 77-361
Range on HMM: 1-513/513
Sequence Identity: 19% (100 aa)

YTLEEWVGDGRYSDVFMGFQ---------------DGQKKCAIKLLKPVNTDRVR---------------RELKILTIIQ----------------GHPC
|.  . .| | |. |. ..                ......||| .| .  .                  ||.|||  ..                 |. 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

ILNLMDIVIDGKEGIP---------------SMITEYVPNSTWRTLFST------------------------------MDLEDIRFYTYRILQALS--Y
|..| ||. . ..  .                ...||.... .. . ..                              . . .|| |.| ||..|   |
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKY

THSKG--IMHRDVKPLNILCNSPRNK-------------------VILADWGLAEFYHP----------------------MRKYSVHVATRYYKSPEIL
 ||..  |.||| || ||| |.                       . ..|.||| .|||                      .| |.  |.||.|..||||
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEIL

LDYEYYD---------YSLDIWSVGVILLELLTL-------KLHVFDGGDN-----------EHQIDSIVEVIGGAP---------------ILDWARKY
| ...|.         .. |.|||| |. |..|        .   | | ..            .|.. |..|.|  .                 .|  . 
LGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMI

R--------------------VKIHREERER---FSQMKGQSFETLIPFSR------------------------------RKFRDPEALDLVNKMLTID
                      .  |  ...   | . ...... |.|...                              ||  ||.|.||..|||..|
KLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYD

HKERITADEALQHPFF
...||||..|||||.|
PDKRITAEQALQHPYF
Kinase 82569.m00144.AA S_TKc 77-361 26 1.2e-61 212.0 SMART 1-231 (231) Show / Hide 
Range on Protein: 77-361
Range on HMM: 1-231/231
Sequence Identity: 26% (81 aa)

YTLEEWVGDGRYSDVFMGFQDG-QKKCAIKLLKPVNTDRVRRELKILTIIQGHPCILNLMDIVIDGKEGIPSMITEYVPN---STWRTLFST--------
|.. . .| | .. |. .   . ....||| .|    ...|||..||    .|| | .| |.  |   .   |..||...   .  . . .         
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

MDLEDIRFYTYRILQALSYTHSKGIMHRDVKPLNILCNSPRNKVILADWGLAEFYHPMRKYSVHVATRYYKSPEILLDYEYYDY-SLDIWSVGVILLELL
..  ..|||.| |..|| | ||.||.|||.|| |||...    . ..| ||| ..      .  . |..| .||.|     |.. . |.||.|.|| |.|
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

TLKLHVFDGGDNEHQIDSIVEVIGGAPILDWARKYRVKIHREERERFSQMKGQSFETLIPFSRRKFRDPEALDLVNKMLTIDHKERITADEALQ------
.     |.      |.. . ..||                                           .|||.|...|.|. | ..|.|| ||||      
C-GYPPFP------QMQMMFKKIG-------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIK

-HPFF
 ||.|
CHPWF
Kinase 82569.m00144.AA Pkinase 77-361 27 3.6e-61 214.33 Pfam 1-293 (293) Show / Hide 
Range on Protein: 77-361
Range on HMM: 1-293/293
Sequence Identity: 27% (87 aa)

YTLEEWVGDGRYSDVFMGFQDGQKK-CAIKLLKPVNTDR-----VRR--ELKILTIIQGHPCILNLMDIVIDGKEGIPSMITEYVPN-----STW-----
|.... .| | .. |. .   |  |  |.| .| ....       ||  |..|.  . .||.|. | |.. |  .. . |..||...     . .     
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST

--RTLFSTMDLEDIRFYTYRILQALSYTHSKGIMHRDVKPLNILCNSPRNKV----ILADWGLAEF--YHPMRKYSVHVATRYYKSPEILLDYEYYDYSL
  .. |. .. ....|| | ||..| | ||.||.|||.|| |||..  .. .     ..|.|||..  | . . ... . |..| .||......||... 
WRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DIWSVGVILLELLTLKLHVFDGG---DNEHQIDSIVEVIGGAPILDWARKYRVKIHREERERFSQMKGQSFETLIPFSRRKFRD---PEALDLVNKMLTI
|.||.|.|| |.|. .   |.|    || |  . ... |.| |.|.. . .   | ...  |. . .         | ...| .   .|..|.....|. 
DMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMG-PPLHFDWPWWCSISYFF-FRH-W-H---------F-HWTF-HNWSEECKDFIKWCLCK

DHKERITADEALQHPFF
| |.|.||...||||.|
DPKKRPTAEQILQHPWF
Kinase 82569.m00144.AA CDK 117-361 29 1.1e-49 157.06 In-house 57-284 (284) Show / Hide 
Range on Protein: 117-361
Range on HMM: 57-284/284
Sequence Identity: 29% (80 aa)

RELKILTIIQGHPCILNLMDIVIDGK---------EGIPSMITEYVPNSTWRTLFSTMDLEDIRFYTYRILQALSYTHSKGIMHRDVKPLNILCNSPRN-
|| ..|  .  || | .|.|.... .         |   .|. ||..      | . ||   |. |.. .|..|.| ||..||||| || ||| |.  . 
REISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEYMDH----DLKKYMD---IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEV

---KVILADWGLAEFYH-------PMRKYSVHVATRYYKSPEILLDYEYYD--YSLDIWSVGVILLELLT--LKLHVFDGGDNEHQIDSIVEVIGGAPIL
   .. .|| |||  ..       |.|.|.  | |. | .||.||  . |.   . |.|||| |. |..|   .   | |    .|.. | ...|     
KCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTED

DWARKYRVKIHREERERFSQMKGQSFETLIPFSRRKFRDPEALDLVNKMLTIDHKERITADEALQHPFF
.|        .                                || ||||. | | ||.|..|||||.|
NWPGVTKLPDY--------------------------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase 82569.m00144.AA Ciliate-E2 77-361 19 6.4e-43 145.17 In-house 1-365 (365) Show / Hide 
Range on Protein: 77-361
Range on HMM: 1-365/365
Sequence Identity: 19% (79 aa)

YTLEEWVGDGRYSDVFMG------------FQDGQK--------KCAIKL--LKPVNTDRVRRELKILTIIQ------------------GHPCILNLMD
| . .  | | ...|. .            ..| ||        |..||.  .| .. . ..  .... |..                   || |... .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

IVIDGKEGIPSMITEYVPNSTWRT------LFST--------MDLEDIRFYTYRILQ---------------ALSYTHSKG-IMHRDVKPLNILCNSPRN
  .. ..    ...||.   . .       ....        .... |..... |||               || | |||. |.||| || |||      
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

KVILADWGLAEFYHPM---------RKYSVHVA------------------------TRYYKSPEILLDYEY--------YDYSLDIWSVGVILLELLTL
 . ..|.||. .|..          .|                              | .|..||||   .|        |||. ||||.|||| |.|. 
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

KLHVFDGGDNEHQIDSIVEVIGGAPILDWARKYRVKIHREERERFSQMKGQSFETLIPFSRRKF------RDPEALDLVNK----MLTIDHKERIT-ADE
|.                                 ... .   .|.. . |.  |. .    .        ..|. || .|    ||  | ..||| ...
KPPF------------------------------QQQIKQCKIDFPCPEWQKD-TQ-CI-Q-CKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQ

ALQHPFF
.|.||.|
ILNHPWF
Kinase 82569.m00144.AA CAMK 82-259 18 5.1e-39 122.89 In-house 1-324 (425) Show / Hide 
Range on Protein: 82-259
Range on HMM: 1-324/425
Sequence Identity: 18% (59 aa)

WVGDGRYSDVFMGFQ-DGQ------------KKCAIKLLK-------------------------------PVNTDRVRRELKILTIIQG------HPCI
  | |... |. ...   .            .|.||| ..                               |.. ..||||..|.  .||      ||.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LNLMDIVIDGKE------------GIPS------MIT---EYVPNS---TW-------RTLF------------STMDLEDIRFYTYRILQALSYTHSKG
..| ..  |..              . .      |..   ||...             .. .              .. .. |.|   |..|. | ||..
IKLYEVYEDPHYFKNTNDYETSKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IMHRDVKPLNILCNSPR----------------NKVILADWGLAEFYHP------------------------MRKYSVHVATRYYKS-PEILLD-----
|.||| || |||...                  |.. ..|.|.| .. |                          |..  . | .| . ||.|.      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------YEYYDYSLDIWSVGVIL
         .||... |.||.||||
MQNATDEEKPYYGPKCDMWSCGVIL
Kinase 82569.m00144.AA p38 168-361 39 8.5e-38 126.6 In-house 106-289 (289) Show / Hide 
Range on Protein: 168-361
Range on HMM: 106-289/289
Sequence Identity: 39% (77 aa)

EDIRFYTYRILQALSYTHSKGIMHRDVKPLNILCNSPRNKVILADWGLAEFYHPMRKYSVHVATRYYKSPEILLDYEYYDYSLDIWSVGVILLELLTLKL
. |.|  | || .| | || || ||| || ||  |      || | |||   |   .   .|||| |..|||.|    |.   |||||| |. ||.| . 
DHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRIL-DFGLAR--HCDDEMTGYVATRWYRAPEIMLNWMHYTQTVDIWSVGCIMAELITGRT

HVFDGGDNEHQIDSIVEVIGGAPILDWARKYRVKIHREERERFSQMKGQSFETLIPFSRRKFRDPEALDLVNKMLTIDHKERITADEALQHPFF
  | | |  .|.  |..|. | |      |   .  |   .  .||. . |... .       .| |.||  ||| .|   |||| ||.|||.|
-LFPGDDHIDQLQRIMKVC-GTPDEEFWQKIQSEEARNYIQSYPQMPRRDFHHVFM-----GANPQAIDLLEKMLELDPDKRITAEEAMQHPYF
Kinase 82569.m00144.AA CDC2 165-266 40 4.1e-31 92.47 In-house 100-206 (301) Show / Hide 
Range on Protein: 165-266
Range on HMM: 100-206/301
Sequence Identity: 40% (44 aa)

MDLEDIRFYTYRILQALSYTHSKGIMHRDVKPLNILCNSPRNKVILADWGLA-EFYHPMRKYS--VHVATRYYKSPEILLDYEYYDYSLDIWSVGVILLE
|... .. |.| |||.... |...||||| || ||| ..  | . .|| |||  |  |.|.|     | |. | .|||||  ..|. . |.||.| |. |
MPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGN-IKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAE

L---LTLK
.    | |
MFMDVTKK
Kinase 82569.m00144.AA RCK 170-266 38 5.6e-27 82.41 In-house 107-211 (298) Show / Hide 
Range on Protein: 170-266
Range on HMM: 107-211/298
Sequence Identity: 38% (42 aa)

IRFYTYRILQALSYTHSKGIMHRDVKPLNILCNSP--------RNKVILADWGLA-EFY--HPMRKYSVHVATRYYKSPEILLDYEYYDYSLDIWSVGVI
|... | |||.|.. |..|..|||.|| ||.|..         .. . .|| ||. |..  .|   |   | ||.| .||.||   ||.. .|||.|| |
IKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPPYTDY---VSTRWYRAPECLLRCTYYNSPMDIWAVGCI

LLELLTLK
  || .|.
MYELYMLR
Kinase 82569.m00144.AA MAPK 310-361 38 1.9e-18 60.2 In-house 278-328 (328) Show / Hide 
Range on Protein: 310-361
Range on HMM: 278-328/328
Sequence Identity: 38% (21 aa)

FSQMKGQSFETLIP---FSRRKFRDPEALDLVNKMLTIDHKERITADEALQHPFF
. .......|...|   |      .|.|.||. |||..| ..|||..||||||.|
LPKYPKKPWEKMFPNANF----NANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase 82569.m00144.AA ERK 229-287 47 5.1e-16 56.3 In-house 177-234 (307) Show / Hide 
Range on Protein: 229-287
Range on HMM: 177-234/307
Sequence Identity: 47% (28 aa)

VATRYYKSPEILLDYEYYDYSLDIWSVGVILLELLTLKLHVFDGGDNEHQIDSIVEVIG
||||.|..|||.| .. |. . ||||.|.|. |.|  |  .| |.|  |||. | ..||
VATRWYRAPEIMLSWQKYTKAMDIWSCGCIFAEMLGRK-PLFPGKDYVHQINRIFQIIG
Kinase 82569.m00144.AA MAPK 228-287 44 1.1e-15 50.45 In-house 191-252 (328) Show / Hide 
Range on Protein: 228-287
Range on HMM: 191-252/328
Sequence Identity: 44% (28 aa)

HVATRYYKSPEILLD--YEYYDYSLDIWSVGVILLELLT-LKLHVFDGGDNEHQIDSIVEVIG
.||||.| .|||.|   .  |. . |.|||| |. |.||  |   | | |  .|.  |.||.|
YVATRWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKP-LFPGKDYIDQWNLIMEVLG
Kinase 82569.m00144.AA ERK 314-361 36 1.9e-15 54.14 In-house 263-307 (307) Show / Hide 
Range on Protein: 314-361
Range on HMM: 263-307/307
Sequence Identity: 36% (18 aa)

KGQSFETLIPF-SRRKFRDPEALDLVNKMLTIDHKERITADEALQHPFF
.....|...|. .      |.|.||  |||..| ..|||..|.|.||.|
PPKPWENIFPNAN----CNPQAIDLLEKMLVFDPDKRITVEECLEHPYF
Kinase 82569.m00144.AA RCK 332-361 50 3.6e-15 44.29 In-house 269-298 (298) Show / Hide 
Range on Protein: 332-361
Range on HMM: 269-298/298
Sequence Identity: 50% (15 aa)

PEALDLVNKMLTIDHKERITADEALQHPFF
.....|..|||..| ..|||| .|||||.|
QDCIELMEKMLQWDPQKRITAQQALQHPYF
Kinase 82569.m00144.AA CAMK 324-361 36 1.4e-13 39.38 In-house 390-425 (425) Show / Hide 
Range on Protein: 324-361
Range on HMM: 390-425/425
Sequence Identity: 36% (14 aa)

FSRRKFRDPEALDLVNKMLTIDHKERITADEALQHPFF
|  . | ..|. ||..|||. | ..|.|....|.||..
F-HH-FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 82569.m00144.AA CDC2 331-361 58 1.9e-13 37.19 In-house 271-301 (301) Show / Hide 
Range on Protein: 331-361
Range on HMM: 271-301/301
Sequence Identity: 58% (18 aa)

DPEALDLVNKMLTIDHKERITADEALQHPFF
|||..|| ..|| .|   ||.|.||||||.|
DPEGIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase 82569.m00144.AA TyrKc 77-318 19 9.2e-10 -64.78 SMART 1-280 (280) Show / Hide 
Range on Protein: 77-318
Range on HMM: 1-280/280
Sequence Identity: 19% (55 aa)

YTLEEWVGDGRYSDVFMGFQDGQKKCAIKLLKPVNTDRVRRELKILTII-QGHPCILNLMDIVIDGKE-----GIPSMITEYVPN--------STWRTLF
 ||..  | | .  |. |  .   ..|.| ||.      .||..|.. .   ||.|..|  .......     . . ...||.|.        .. ..  
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK--

STMDLEDIRFYTYRILQALSYTHSKGIMHRDVKPLNILCNSPRNKVILADWGLAEFYHPM-------RKYSVHV--ATR-----YYKSPEILLDYEYYDY
    ..|   . . | .  .| |||.. |||    |.| ....  |  .| ||. . .           |..     ..        .|| . ....   
--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTK

SLDIWSVGVILLELLTLKLHVFDGG----DNEHQIDSIVEVIGGAPILDW--------ARKYRVKI-------HREERERFSQMKGQSF
| |.|| || . |..|.      |      .  ..   |.  .  |. .         . .   .|         |.| .||.   . |
S-DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase 82569.m00144.AA MAPK 77-203 26 6.8e-08 23.15 In-house 1-152 (328) Show / Hide 
Range on Protein: 77-203
Range on HMM: 1-152/328
Sequence Identity: 26% (40 aa)

YTLEEWVGDGRYSDVFMGFQDG-------QKKCAIKLLK-----PVNTDRVRRELKILTIIQGHPCILNLMDIVIDGK---EGIPS------MITEYVPN
|.. . .| | |  |.. ..         .|| ||| .      |. . |. ||.|.|  . .|. | .| ||    .   .. ..      ...|.   
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

STWRTLFST--MDLEDIRFYTYRILQA--LSYTHSKGIMHRDVKPLNILCNS
   . . |   .. . |.. .| || .  | | || .. ||| || |||.|.
DLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNE
Kinase 82569.m00144.AA ERK 170-203 50 1.3e-07 24.65 In-house 110-143 (307) Show / Hide 
Range on Protein: 170-203
Range on HMM: 110-143/307
Sequence Identity: 50% (17 aa)

IRFYTYRILQALSYTHSKGIMHRDVKPLNILCNS
. . .| || .| | || ...||| || |||.||
CQYFMYQILCGLKYIHSANVIHRDLKPSNILVNS
Kinase 82569.m00144.AA Pkinase_Tyr 77-155 24 0.000187 15.71 Pfam 1-91 (270) Show / Hide 
Range on Protein: 77-155
Range on HMM: 1-91/270
Sequence Identity: 24% (22 aa)

YTLEEWVGDGRYSDVFMGFQD-----GQKKCAIKLLKPVNTDR------VRRELKILTIIQGHPCILNLMDIVIDGKEG-IPSMITEYVPN
 |. .  | | . .|..|  .     .. ..|.| ||.  ...        ||.||.. .  || |..|. ...| .|   . ...||.|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPH
Kinase 82569.m00144.AA RCK 77-108 30 0.014496 3.63 In-house 1-33 (298) Show / Hide 
Range on Protein: 77-108
Range on HMM: 1-33/298
Sequence Identity: 30% (10 aa)

YTLEEWVGDGRYSDVFMGFQ-DGQKKCAIKLLK
|.. . .||| |..|...   . ... ||| .|
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMK