Gene 84370.m00118 (T.vaginalis)

84370.m00118

Species: T.vaginalis
Alias: 84370.m00118, TvagK0651
External Links:
Annotation:

Classification

Group: CMGC
Family: DYRK
Subfamily: YAK

Sequence

Name Sequence Type Origin Length Description Download
84370.m00118.AA Protein None 381 None Fasta, JSON
84370.m00118.kin_dom Protein Kinase Domain None 327 None Fasta, JSON

Protein domain

Protein domains of 84370.m00118.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 84370.m00118.AA DYRK 50-376 28 2e-70 240.26 In-house 1-320 (320) Show / Hide 
Range on Protein: 50-376
Range on HMM: 1-320/320
Sequence Identity: 28% (98 aa)

YTLVDKVGEGHFGNVYEVNRNSENDNNQSFAMKISKAEQNSIEQFNYETLVMQYINQNARGNNQYYIPFMHDNFMYNGHLCIILDLGGPNLYNVLASRNF
|. ..  | | ||.|  .  .    .|. .|.|| . ..    |   |.   .|.||.   ...|..  | | |.. .||||. .|   ||| .|  ..|
YEILEYIGKGSFGQVVKCWDH---KTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQ-DPDDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNHF

EGL-SLANIQTIARDLFMALVAIHRI-GVIHTDIKPENIVQTNP-FSVHVKLIDFGNSITLNNTYEQYFQTRYYRAPETVLQLNIDTKIDIWSLGCVLCE
 |. || .....|. .. .|. .|.    || |.|||||.  .|     .|.|||| |   . .  .| | |.|||||  |..  ...||.|||||.| |
QGFFSLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLKQPRNKSTIKVIDFGSSCFEHQRIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAE

LFLGLPILPAMNEYHLVSLIEQTIGPFPTNMVEQS--VRRNAMFDTDYTVKSAQTISQEEPDMSFESFEPYFVYTQLRDILE-NYPVDSSFN--------
||.| |..|  |||..  .| ...|..| .|....   |..  ||                          | |.....  . |.. | ...        
LFTGWPLFPGENEYDQLACIMEVLGMPPKWMIDKGRCRRKHKFFDC-------------------------FMYCECDEWTKQNKITDHYMTPKCHPTKR

---------EERERLEIQRRDQFINLVIQMLKIDPDDRLSAEEALAHPFM
             |.. . ..||.... ..|..||. |.....|| ||. 
GQRRPPGRRNWDPRHQ-CDDHQFKDFIKKCLQWDPHKRITPSQALQHPWF
Kinase 84370.m00118.AA CMGC 50-376 16 2.2e-67 220.16 In-house 1-513 (513) Show / Hide 
Range on Protein: 50-376
Range on HMM: 1-513/513
Sequence Identity: 16% (87 aa)

YTLVDKVGEGHFGNVYEVNRNSEN-----------DNNQSFAMKISK-AEQNSIEQF------------NYETLVMQYI--NQNARG---------NNQY
|. ..|.|||..|.||.   .  |           ..|.  |.|. | .. . ...             . |   ....  |... .         ..  
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDP-NWQRRDDPDNKHHN

YIPFMHDNFMYNG-----------------HLCIILDLGGPNLYNVLASRN--FEG------------------------LSLANIQTIARDLFMALV--
.|  ..| |....                 ||... .. . .||... . .  . |                        ... .|. ... .. .|   
NIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLK

AIHRIG--VIHTDIKPENIVQTNPFSV------------------HVKLIDFGNSITLNNT------------------------YEQYFQTRYYRAPET
 .|. .  .||.|.|||||  ..   .                  ..|..|||..  ...                         | .| .||.||||| 
YCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEI

VLQLN----------IDTKIDIWSLGCVLCELFLG--------LPILPAMNE-----------YHLVSLIEQTIGPFPTNMVEQSVRRNAMFDTDYTVKS
 |              .|.||.||.||.. |...|         |. |  .|           ..   .| ...|... .| ...  |.  |      . 
LLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGK-RH--F------N-

AQTISQEEPDMSFESFE------------------------------PYFVYTQLRDILENYPVDSSFNEER----------ERLEIQRR----------
  . ..| |.|.                                   | . .  ....  ..|  .  | ..          |.   . .          
FCKHEEEWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDD-N-NKKAMVFNWIYEEKFKSH-KFNHQFKRKCC

-DQFINLVIQMLKIDPDDRLSAEEALAHPFM
 .|.|.|. .||..|||.|..||.||.||. 
DPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase 84370.m00118.AA S_TKc 50-376 19 2.3e-57 197.83 SMART 1-231 (231) Show / Hide 
Range on Protein: 50-376
Range on HMM: 1-231/231
Sequence Identity: 19% (68 aa)

YTLVDKVGEGHFGNVYEVNRNSENDNNQSFAMKISKAEQNSIEQFNYETLVMQYINQNARGNNQYYIPFMHDNFMYNGHLCIILDLGGP---NLYNVLAS
|....|.|.| || || .  ..    .. .|.|| |      |..  |  ...         .  .|  ..| |   .||...... .    .|. .. .
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK------EHIRREIQILKK--------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKK

RNFEG----LSLANIQTIARDLFMALVAIHRIGVIHTDIKPENIVQTNPFSVHVKLIDFGNSITLNNTYEQYFQTRYYRAPETVLQLNIDT-KIDIWSLG
|. .|    ..   .. ... .. ||  .|. |.|| |.|||||  ..    |.|..||| .  |      .  |..|.||| .     .. |.|.||.|
RGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

CVLCELFLGLPILPAMNEYHLVSLIEQTIGPFPTNMVEQSVRRNAMFDTDYTVKSAQTISQEEPDMSFESFEPYFVYTQLRDILENYPVDSSFNEERERL
|.| |.. | |  |       . .. . ||                                                                      
CILYEMLCGYPPFP------QMQMMFKKIG----------------------------------------------------------------------

EIQRRDQFINLVIQMLKIDPDDRLSAEEALA-------HPFM
     ....... ..|. ||..|..| |||.       ||..
----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 84370.m00118.AA YAK 50-376 30 4.6e-50 168.1 In-house 1-347 (347) Show / Hide 
Range on Protein: 50-376
Range on HMM: 1-347/347
Sequence Identity: 30% (107 aa)

YTLVDKVGEGHFGNVYEVNRNSENDNNQSFAMKISKAEQNSIEQFNYETLVMQYINQNARGNNQY---YIPFMHDNFMYNGHLCIILDLGGPNLYNVLAS
|   |  | | || |      . .| |  || |. |  |    |   | .. .  ||    ||      |  | | | .  |.|..  .   |||  |  
YIVLDMLGQGTFGQVV---KCQNCDTNELFAVKVIKNRQAYFQQAKNEIQILRVLNQQHDPNNKNYQKHILRMYDFFVHKNHFCLVFEMLSNNLYEYLKQ

RNFEGLSLANIQTIARDLFMALVAIHRIGVIHTDIKPENIVQTNPFSVHVKLIDFGNSITLNNTYEQYFQTRYYRAPETVLQLNIDTKIDIWSLGCVLCE
 .| |.|   |..       ...      .|| | |||||   .| .  .|.|||| |     .   | | |.||.|| ..     | || |||||.. |
NKFCGFSFQLIRQWTKQILDGMCVLENKQIIHCDLKPENIMLCKPNKPEIKIIDFGSSCQEKKMVYTYIQQRHYRSPEIIVWMIYCTSIDMWSLGCIVAE

LFLGLPILPAMNEYHLVSLIEQTIGPFPTNMVEQSVRRNAMF---DT------------------DYTVKSAQTISQEEPDMSFESFEPYFVYTQLRDIL
||||||| |   ||  .. |  . | .|  |..|   .|  |   |                    |. |. |    .|     ||   || |  | || 
LFLGLPIFPGNSEYNQIKRIIDMLGYPPSWMIDQGRFKNKYFHCHDGSNSDDNNNNNNNNNGKPYYYIFKTKQDYQIDEKIQLKESKT-YFQYKCLNDIK

ENYPVDSSFNEERERLEIQRRDQFINLVIQMLKIDPDDRLSAEEALAHPFM
...    .   .    . ..|| || .. |.|  .|  | ..  |  |||.
NYMYFKQFMRNQDDTKNNRHRDCFIDFINQLLQLNPRERWKPMQAMQHPFI
Kinase 84370.m00118.AA HIPK 50-376 28 1e-49 154.47 In-house 1-329 (329) Show / Hide 
Range on Protein: 50-376
Range on HMM: 1-329/329
Sequence Identity: 28% (95 aa)

YTLVDKVGEGHFGNVYEVNRNSENDNNQSFAMKISKAEQNSIEQFNYETLVMQYINQNARGNNQYYIPFMHDNFMYNGHLCIILDLGGPNLYNVLASRNF
|  ..  | | || |    . . |.     |.|| | .     |   |  ... . |     ..| .  . . |    | |.. ..   |||. .   .|
YEVLEFLGRGTFGQVVKCWKRGTNE---MVAIKILKNHPYYARQGQIEVSILHCLSQEN--ADEYHFVRAYECFHHKNHTCLVFEMLEQNLYDFQKQNKF

EGLSLANIQTIARDLFMALVAIHRIGVIHTDIKPENIVQTNPFSV--HVKLIDFGN-SITLNNTYEQYFQTRYYRAPETVLQLNIDTKIDIWSLGCVLCE
  | |  | .|      ||. .  .|.|| |.|||||    |      || ||||  |.  .   . | | ||||||| .| | .  ..|.||||||. |
MPLPLKHIRPILQQVLTALMKLKELGLIHADLKPENIMLVDPTRCPYRVKVIDFGSASHVSKVVCNTYLQSRYYRAPEIILGLPFCENHDMWSLGCVIAE

LFLGLPILPAMNEYHLVSLIEQTIGPFPTNMVEQSVRRNAMF----DTDYTVKSAQTISQEEPDMSFESFEPYFVYTQLRDILENYPVDSSFNEERERLE
|||| |  |  .|| ..  |.|| .   . .... .. . .|    . .. .    .| . | . |  | |         |   .  .    . .  | |
LFLGWPLYPGADEYDQIRYICQTQHLPHEHLLHAACKKHRFFDRDKQSKFRPWRLKHIEEHEQQTSVKSKEARKYIFNCLDDMPEVNMLVDPERQDYRVE

IQRRDQFINLVIQMLKIDPDDRLSAEEALAHPFM
   | .|...  .|. .|.. |..  ||| ||| 
KIDRREFVHVLKKMCTWDAHKRITPCEALNHPFV
Kinase 84370.m00118.AA DYRK1 50-291 32 5.4e-46 159.12 In-house 1-240 (321) Show / Hide 
Range on Protein: 50-291
Range on HMM: 1-240/321
Sequence Identity: 32% (80 aa)

YTLVDKVGEGHFGNVYEVNRNSENDNNQSFAMKISKAEQNSIEQFNYETLVMQYINQNARGNNQYYIPFMHDNFMYNGHLCIILDLGGPNLYNVLASRNF
|     .| | || |       .. . .  |.|| |  .  ..|   |  ..  .|.. . ...|||  .   ||.  |||....|   ||| .|   .|
YEIDSLIGKGSFGQVVKAY---DHQEQEYVAIKIIKNKKPFYNQAQIEIRLLELMNKHDK-EMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHF

EGLSLANIQTIARDLFMAL--VAIHRIGVIHTDIKPENIVQTNPFSVHVKLIDFGNSITLNNTYEQYFQTRYYRAPETVLQLNIDTKIDIWSLGCVLCEL
 | ||  .. .|. .  ||  ..   . .|| |.|||||.  ||    .|.|||| |  |..   || | |.||.|| .|... |..||.|||||.| |.
RGVSLNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENILLCNPKRSAIKIIDFGSSCQLGQRIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEM

FLGLPILPAMNEYHLVSLIEQTIGPFPTNMVEQSVRRNAMFDTD
  | |.    ||   .. |   .|  | .|..|. .    |. |
HTGEPLFSGSNEVDQMNKIVEVLGMPPKHMIDQAPKAHKYFEKD
Kinase 84370.m00118.AA DYRK2 50-255 30 1.4e-45 146.04 In-house 1-203 (318) Show / Hide 
Range on Protein: 50-255
Range on HMM: 1-203/318
Sequence Identity: 30% (64 aa)

YTLVDKVGEGHFGNVYEVNRNSENDNNQSFAMKISKAEQNSIEQFNYETLVMQYINQNARGNNQYYIPFMHDNFMYNGHLCIILDLGGPNLYNVLASRNF
|...   | | || | ..       ..|  | |.   ..   .|   |. ....| .. . .|.. .  | | |.. .|.|| ..| . |||  .  ..|
YEILEVIGKGSFGQVVKC---YDHKTKQHVAIKMIRNKKRFHNQAYEEIRILHHIRRQDK-DNTMNCVHMLDYFYFRNHHCITFELLSMNLYEYIKKNHF

EGLSLANIQTIARDLFMALVAIHRIGVIHTDIKPENIVQTNPFSVHVKLIDFGNSITLNN-TYEQYFQTRYYRAPETVLQLNIDTKIDIWSLGCVLCELF
 |.||...   |. .  .|.. |.  .|| | |||||.   .    .|.|||| |   .      | |.|.|||||  |..  .. ||.||.||.. ||.
QGFSLQLVRRFAHSILQCLRFLHKNNIIHCDLKPENILLKQWNRSGIKVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELY

LGLPILP
 | |..|
TGYPLFP
Kinase 84370.m00118.AA Pkinase 50-376 19 1.3e-43 155.26 Pfam 1-293 (293) Show / Hide 
Range on Protein: 50-376
Range on HMM: 1-293/293
Sequence Identity: 19% (68 aa)

YTLVDKVGEGHFGNVYEVNRNSENDNNQSFAMKISKAEQNSIEQFNY-----ETLVMQYINQNARGNNQYYIPFMHDNFMYNGHLCIILDLGGP-----N
|... |.|.| || ||.  . ....    .|.|| | . .. ..  .     |  .|. .|      |   |  ..| |....|....... .       
YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN----HPN---IVRLYDWFEDKDHIYMVMEYCEGGLYVMD

LYNVLA---SRNFEGLSLANIQTIARDLFMALVAIHRIGVIHTDIKPENIVQTNPFSV--HVKLIDFGNS----ITLNNTYEQYFQTRYYRAPETVL-QL
|. ..    ...|  .|   .. ... .. .|  .|. |.|| |.|||||   |   .  .||..||| .    .  |  .  .  |..|.||| .. . 
LFDYISTWRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQ

NIDTKIDIWSLGCVLCELFLGLPILPAM------NEYHLVSLIEQTIGPFPTNMVEQSVRRNAMFDTDYTVKSAQTISQEEPDMSFESFEPYFVYTQLRD
 ...|.|.||.||.| |...| |. |        ...... .| ... .|.        ...  .. . .                              
YYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H------------------------------

ILENYPVDSSFNEERERLEIQRRDQFINLVIQMLKIDPDDRLSAEEALAHPFM
            . .... .   . .. ..  .|. || .|..||..| ||..
------------F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 84370.m00118.AA Ciliate-E2 50-376 17 2e-34 115.59 In-house 1-365 (365) Show / Hide 
Range on Protein: 50-376
Range on HMM: 1-365/365
Sequence Identity: 17% (79 aa)

YTLVDKVGEGHFGNVYEVNRNSEN--------------------DNNQSFAMKISKAEQNSIEQFNYETLVMQYIN---------QNARGNNQYYIPFMH
| .. | |.| || ||.... ...                    .... .|||| |  .| |||.. |  .|. ||         .. . .|  .|  |.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMK--KNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMY

DNFM--YNGHLCIILDL-GGPNLYNVLA----SRNFE-----GLSLANIQTIARDLF---------------MALVAIHRIG-VIHTDIKPENIVQTNPF
. |    . .. .....  | .|.  .     .||.|      ...  |..| . ..                ||  .|  . .|| |||||||.     
ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

SVHVKLIDFGNSITLNNTYEQYFQ----------------------------------TRYYRAPETVLQLN---------IDTKIDIWSLGCVLCELFL
   .|.||||.|  ... ......                                  | .| ||| .   .          |.|.||||||..| |.  
---IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

G-LPILPAMNEYHLVSLIEQTIGPFPTNMVEQSVRRNAMFDTDYTVKSAQTISQEEPDMSFESFEPYFVYTQLRDILENYPVDSSFNEERER--------
| .|                                                                      .. .. ..| ...| ...        
GKPPF--------------------------------------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKW

-LEIQRRDQFINLVIQ----MLKIDPDDRLS-AEEALAHPFM
    .  .. ..|  .    ||. ||. |.. .|..| ||..
KSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 84370.m00118.AA CLK 50-186 31 2.6e-30 87.52 In-house 1-145 (350) Show / Hide 
Range on Protein: 50-186
Range on HMM: 1-145/350
Sequence Identity: 31% (46 aa)

YTLVDKVGEGHFGNVYEVNRNSENDNNQSFAMKISKAEQNSIEQFNYETL-VMQYINQNARGNNQYY--IPFMHDNFMY-NGHLCIILDLGGPNLYNVLA
|. |...||| || |.|.. ..  ..    | || ..     |.   |.  .|. ||..   ||.|   .  | | | | .|| ||. .| | ..| .. 
YEIVCTLGEGTFGKVVECWDHKNGKK--YVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFDYGHGHICIVFELYGLSIYDFMK

SRN------FEGLSLANIQTIARDLFMALVAIHRIGVIHTDIKPENI
| |      .... .. |. .|. |  |.   | .. .||| |||||
SNNSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHDMKLTHTDLKPENI
Kinase 84370.m00118.AA DyrkP 76-279 34 1.2e-27 87.54 In-house 24-230 (323) Show / Hide 
Range on Protein: 76-279
Range on HMM: 24-230/323
Sequence Identity: 34% (72 aa)

NQSFAMKISKAEQNSIEQFNYETLVMQYINQNARGNNQYYIPFMHDNFMYNGHLCIILDLGGPNLYNVLA-SRNFEG---LSLANIQTIARDLFMALVAI
|| . |||    .   .|   |  ...||| |     .  .  ..| |    || || .|   |||      |  |      .  .| |   . .||  |
NQMMCMKIIENNKDYFDQSIDEIKLLRYINYNGDVDEKNVL-RYYDYFYHKEHLFIITELLKDNLYEFYKFNRENEQQRYFTVGRLQKITQQILIALDYI

HRIGVIHTDIKPENIVQTNPFSVHVKLIDFGNSITLNNTYEQYFQTRYYRAPETVLQLNIDTKIDIWSLGCVLCELFLGLPILPAMNEYHLVSLIEQTIG
| . .|| |.|||||.       .||.|||| |  .      | | | ||||| ..    | .||.|||||.| ||. |  .    |   |.  .   ||
HSLRLIHCDLKPENILMKSYPKCQVKIIDFGSSCFIHDHLSSYVQSRSYRAPEVIIGCKYDYRIDMWSLGCILAELWTGNVLFQNDNIQGLLARVIGIIG

PFPTNMVE
|||  |..
PFPEWMMQ
Kinase 84370.m00118.AA Ciliate-E2-Unclassified 50-252 22 5.7e-24 80.05 In-house 1-268 (352) Show / Hide 
Range on Protein: 50-252
Range on HMM: 1-268/352
Sequence Identity: 22% (61 aa)

YTLVDKVGEGHFGNVYEVNRNSENDNNQSFAMKISKAEQNSI-----EQFNYETLVMQYINQNARGNNQY----------------YIPFMHDNFMYNGH
|... . |.| || ||.. .  .... | .|||. |  |.       ..   . . |. .|..   ..|                 .|  |.. |    .
YKIIKQIGQGGFGKVYKCQH--KKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQN

LCIILDLG-GPNLYNVLASRNF---------------EGLSLANIQ-----TIARDLFMALVAIHRIG-VIHTDIKPENIVQTNPFS-VHVKLIDFGNSI
..|....  | .| . . .|..               . ..  ...     .... .  .|  .|. . .|| |||||||. .|  .  ..|.||||.|.
IYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISK

--TLNNTYEQYFQ-----------------TRYYR----APETVLQLNID----TKIDIWSLGCVLCELFLGLP
    || .. ..|                 | .|     |||   . | |     |.||||||..| |.  | .
KYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYY
Kinase 84370.m00118.AA CLK 193-283 31 1.5e-14 39.33 In-house 183-277 (350) Show / Hide 
Range on Protein: 193-283
Range on HMM: 183-277/350
Sequence Identity: 31% (30 aa)

SVHVKLIDFGNSITLNNTYEQYF---QTRYYRAPETVLQLNIDTKIDIWSLGCVLCELFLGLPILPAMNEYHLVSLIEQTIG-PFPTNMVEQSVR
. |...||||. .. .  .|      .|| ||||| .| |   .. |.|| ||.| || .|    .  ..     ..|   | |.|  |   ..|
NTHICVIDFGSATKIRFDHEHHSTIVSTRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLFQTHDNREHLAMMERIMGMPIPQWMIQRTRR
Kinase 84370.m00118.AA CLK 347-376 40 3e-09 23.12 In-house 321-350 (350) Show / Hide 
Range on Protein: 347-376
Range on HMM: 321-350/350
Sequence Identity: 40% (12 aa)

DQFINLVIQMLKIDPDDRLSAEEALAHPFM
.|.. |. .|| .||  |... .|| ||| 
RQLFDLIRKMLEYDPSKRITCKDALQHPFF
Kinase 84370.m00118.AA TyrKc 50-376 18 1.5e-07 -100.38 SMART 1-280 (280) Show / Hide 
Range on Protein: 50-376
Range on HMM: 1-280/280
Sequence Identity: 18% (68 aa)

YTLVDKVGEGHFGNVYE-VNRNSENDNNQSFAMKISKAEQNSIEQFNYETLVMQYINQNARG-NNQYYIPF----MHD--NFMYNGHLCIILDLGGP-NL
 || .| |||.|| ||. . .       .  | |  |..   .| |  |  .|  .     | ...  . .    ...  |||| . |.|.. .    .|
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA--REDFMREARIMCKL-----GGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDL

YNVL-ASRNFEGLSLANIQTIARDLFMALVAIHRIGVIHTDIKPENIVQTNPFSVHVKLIDFGNSITLNNT------YEQYF-----QTR-----YYRAP
 . | ..|.   |...    .. .       .|. ..|| |.   |.  ....  .||  ||| |  . .        . |      ...        ||
KDYLRKHRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAP

ETVLQLNIDTKIDIWSLGCVLCELF-LGLPILPA-----MNEYHLVSLIEQT-IGPFPTN---MVEQSVRRNAMFDTDYTVKSAQTISQEEPDMSFESFE
|.       || |.|| | .. |.| .| .  |      |. .... ...|    | | |   |                                    
ECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-----------------------------------

PYFVYTQLRDILENYPVDSSFNEERERLEIQRRDQFINLVIQMLKIDPDDRLSAEEALAHPFM
                    |            |   ..  |  . ||.|| . .|   | ..
--------------------F--------VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 84370.m00118.AA Ciliate-E2-Unclassified 349-376 44 3.3e-07 21.08 In-house 324-352 (352) Show / Hide 
Range on Protein: 349-376
Range on HMM: 324-352/352
Sequence Identity: 44% (13 aa)

FIN-LVIQMLKIDPDDRLSAEEALAHPFM
||| |  .||| .|. |...|..| ||..
FINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 84370.m00118.AA DyrkP 349-376 50 1e-06 17.18 In-house 296-323 (323) Show / Hide 
Range on Protein: 349-376
Range on HMM: 296-323/323
Sequence Identity: 50% (14 aa)

FINLVIQMLKIDPDDRLSAEEALAHPFM
||  | |.|.||   | .| ||| ||..
FIDFVRQCLQIDFTRRPTAKEALQHPWF
Kinase 84370.m00118.AA DYRK2 347-376 30 4e-06 15.5 In-house 289-318 (318) Show / Hide 
Range on Protein: 347-376
Range on HMM: 289-318/318
Sequence Identity: 30% (9 aa)

DQFINLVIQMLKIDPDDRLSAEEALAHPFM
. ||. . . .. ||. |.....|| ||..
ENFIDFIKRCFEWDPSERMTPSQALKHPWI
Kinase 84370.m00118.AA DYRK1 348-376 37 1.1e-05 15.35 In-house 293-321 (321) Show / Hide 
Range on Protein: 348-376
Range on HMM: 293-321/321
Sequence Identity: 37% (11 aa)

QFINLVIQMLKIDPDDRLSAEEALAHPFM
.|  |. .||. ||  |..  .|| |.|.
KFKDLIKRMLQYDPKQRITPYYALQHSFF