Gene 82761.m00546 (T.vaginalis)

82761.m00546

Species: T.vaginalis
Alias: 82761.m00546, TvagK0022
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
82761.m00546.AA Protein None 373 None Fasta, JSON
82761.m00546.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of 82761.m00546.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 82761.m00546.AA CAMK 18-265 23 4.6e-106 342.82 In-house 1-425 (425) Show / Hide 
Range on Protein: 18-265
Range on HMM: 1-425/425
Sequence Identity: 23% (101 aa)

ELGHGAFSTVYAAKKKADV------------EIYAIKVIDIALVEK-------------------------EGDKEHLQREIDVMAY-------LKHENI
.||.|.|..|. .. | .             . .|||.||   . .                         . |.. ..|||..|         |.|.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQLYDFFSD-------------------DVRFFLVL---DYCPGG----DLYAIITQSKH---------------FRETQIAMVFQQIVSAVGYCHSRGV
..||... |                   | ....|.   .||.||    ||.  |.. ..               | | . . .|.||.||| ||||...
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHRDLKPQNVLVTTFP----------------Y-IKISDFGLCGYINE------------------------DKRMKTFCGSPFFSA-PECLKQ------
.|||||| |.|...                  . |||.|||.  ....                        .. ||||||.| . | || |..      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------VQYDGKKSDIWSLGVILFELATGEHPWNPT-------------NTPLMIKQITTASYQ-VPKGLNP-----------------------ACED
        .|.|.|.|.||.||||. . .|. |..               | . . ..|... |.  |. . |                        | |
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LIRSLLKVRPNERPSCEQILQHPWL
|||..|.| |..|...||.|.|||.
LIRKMLQVDPEKRMTIEQCLNHPWM
S_TKc 82761.m00546.AA S_TKc 13-265 35 2.5e-105 357.12 SMART 1-231 (231) Show / Hide 
Range on Protein: 13-265
Range on HMM: 1-231/231
Sequence Identity: 35% (96 aa)

YTLVEELGHGAFSTVYAAKKKADVEIYAIKVIDIALVEKEGDKEHLQREIDVMAYLKHENIVQLYDFFSDDVRFFLVLDYCPG--GDLYAIITQSKH---
|......|.|||..|| ...| . .|.|||.|.          ||..|||...   .|.|||.|||.| |  ....|..||.|  |||. .| . ..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FRETQIAMVFQQIVSAVGYCHSRGVAHRDLKPQNVLVTTFPYIKISDFGLCGYINEDKRMKTFCGSPFFSAPECLKQVQYDGKKSDIWSLGVILFEL
   | | ... ...||..|. ||||.|. ||||||.|.|...   |||.||||.  .      .||||.|.. ||| |   .|...|.|.||.|.||.|.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

ATGEHPWNPTNTPLMIKQITTASYQVPKGLNPACEDLIRSLLKVRPNERPSCEQILQ-------HPWL
..|. |.   .  .|.|.|            | . |.|| .|.. |..||.. ..||       |||.
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 82761.m00546.AA CAMKL 13-265 35 3.4e-102 326.94 In-house 1-297 (297) Show / Hide 
Range on Protein: 13-265
Range on HMM: 1-297/297
Sequence Identity: 35% (105 aa)

YTLVEELGHGAFSTVYAAKK-KADVEIYAIKVID------IALVEK-------EGDKEHLQREIDVMAYLK---HENIVQLYDFFSDDVR------FFLV
|.....||.|.|..|  |.  .   | .|||.||      .  ..|       | |. ...|||  |  |.   |.||..||. . ..        ..||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

LDYCPGGD--LYAIITQSKH----FRETQIAMVFQQIVSAVGYCHSRGVAHRDLKPQNVLVTTFP--YIKISDFGLCGYINE-----DKRMKTFCGSPFF
. ||.||.  |.  | . .|    . | .    |.|||||| ||||.|..|||.|| |.|..      |||.|||.. .. .     .. .||||||| .
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

SAPECLKQ--VQYDGKKSDIWSLGVILFELATGEHPWN-PT-------NTPLMIKQITTASYQVPKGLNP-ACEDLIRSLLKVRPNERPSCEQILQHPWL
 ||| ..    .|||.| ||||.||||. . .|. |.. .|       |. .. ..| .  |. |. . .  |.||||..|.| |..||...||..|||.
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Pkinase 82761.m00546.AA Pkinase 13-265 33 3.6e-96 330.58 Pfam 1-293 (293) Show / Hide 
Range on Protein: 13-265
Range on HMM: 1-293/293
Sequence Identity: 33% (98 aa)

YTLVEELGHGAFSTVYAAKKKADVEIYAIKVIDIALVEKEGDKEHLQ-REIDVMAYLKHENIVQLYDFFSDDVRFFLVLDYCPGG----DLYAIIT--QS
|.... .| |.|..|| ...| . .|.|.|.|.    ... |..|.  .|| .|. |.|.|||.|||.| |. .  .|..||.||    ||...|.  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KHF--RETQIAMVFQQIVSAVGYCHSRGVAHRDLKPQNVLVTTFPYI----KISDFGLCGY--INEDKRMKTFCGSPFFSAPECLKQVQYDGKKSDIWSL
. |   | .. ... ||.... ||||.|. ||||||.|.|.   ..|    ||.||||.    .  .  |.||||.|.. ||| ..  ||.|.|.|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVILFELATGEHPWNPT------NTPLMIKQITTASYQVPKGLN---------------------PACEDLIRSLLKVRPNERPSCEQILQHPWL
|.||.|...|. |.         .   ||..|  . .  .                         ..| |.|...|.. |..||..||||||||.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 82761.m00546.AA MARK 13-265 35 2.9e-90 295.27 In-house 1-262 (262) Show / Hide 
Range on Protein: 13-265
Range on HMM: 1-262/262
Sequence Identity: 35% (94 aa)

YTLVEELGHGAFSTVYAAKKKADVEIYAIKVID-IALVE-KEGDKEHLQREIDVMAYLKHENIVQLYDFFS--DDVR-FFLVLDYCPGGDLYAIITQS--
| .. ..|||....|. |  |   . .|||...   | . ..  .. ..|||..|  |.|.||..|.. .   .  . ..|...|..||.||  | .   
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQW--MKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPN

KHFRETQIAMVFQQIVSAVGYCHSRGVAHRDLKPQNVLVTTFP--YIKISDFGLCGYINEDKRMKTFCGSPFFSAPECLKQVQYDGKKSDIWSLGVILFE
 .  |      |.|||||| ||||....|||.||.|.|.       |||.|||..  |..... .||||.| . ||| ...  |||.| |||||||.|. 
GRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYF

LATGEHPWNPTN--TPLMIKQITTASYQVPKGLNPACEDLIRSLLKVRPNERPSCEQILQHPWL
. .|  |.  ..     . |.|.. .|..|  . . |..||..||.| |.|||..|.|..|||.
MVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 82761.m00546.AA Ciliate-E2 13-265 26 3e-88 299.5 In-house 1-365 (365) Show / Hide 
Range on Protein: 13-265
Range on HMM: 1-365/365
Sequence Identity: 26% (100 aa)

YTLVEELGHGAFSTVYAAKK-----------------------KADVEIYAIKVIDIALVEKEGDKEHLQREID----------VMAYLKHENIVQLYDF
| ... .| |.|..|| .|.                       |... |||.|..    .|    ..|. |||.          ..  |.| ||...|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FS--DDVRFFLVLDYCPGGDLYAIITQSKHFR-----------ETQIAMVFQQIVS---------------AVGYCHSRG-VAHRDLKPQNVLVTTFPYI
|   ||  ..||..|| ||||. .| ..|..|           | .|. ...||..               |. |.||.. . |||.||.|.|.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KISDFGLCGYINED--------------------------------KRMKTFCGSPFFSAPECLKQVQYDG--------KKSDIWSLGVILFELATGEHP
||.||||. ....|                                   .|.||.| . ||| |.  .||.        .|.|||||||||.|. .|..|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

WNPTNTPLMIKQITTASYQVP------------------KGLNPACEDLIRS----LLKVRPNERPS-CEQILQHPWL
.        ..||    .. |                  | . . | |||.     .|.. |..|..  ||||.|||.
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 82761.m00546.AA AMPK 13-265 36 3e-83 246.99 In-house 1-254 (254) Show / Hide 
Range on Protein: 13-265
Range on HMM: 1-254/254
Sequence Identity: 36% (93 aa)

YTLVEELGHGAFSTVYAAKKKADVEIYAIKVIDIALVEKEGDKEHLQREIDVMAYLKHENIVQLYDFF-SDDVRFFLVLDYCPGGDLYAIITQSKHFRET
| . . .| |.|  |  .. .   |  |||...     .. ..| .||||. .  ..| .|.|||.   .    .|.|. | .||.|.  |.. .   | 
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

QIAMVFQQIVSAVGYCHSRGVAHRDLKPQNVLVTTFPYIKISDFGLCGYINEDKRMKTFCGSPFFSAPECLKQVQYDGKKSDIWSLGVILFELATGEHPW
. . .||||.|.| |||  ...|||||| |.|      ||| ||||  . .. .  || ||||   |||      | | . |||| ||||. .  |  | 
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

NPTNTPLMIKQITTASYQVPKGLNPACEDLIRSLLKVRPNERPSCEQILQHPWL
   |||   | |.   |..|| |.| ..|||...|.| |..| . ..| .|||.
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 82761.m00546.AA Ciliate-E2-Unclassified 13-265 26 3.9e-80 272.52 In-house 1-352 (352) Show / Hide 
Range on Protein: 13-265
Range on HMM: 1-352/352
Sequence Identity: 26% (92 aa)

YTLVEELGHGAFSTVYAAKKKADVEI----YAIKVIDIA-LVEKEGDKEHLQREIDVMAY------------------LKHENIVQLYDFFSDDVRFFLV
|.... .|.|.|..|| ...| . ..    |..|..... .  .. | |... .. ..                    ..|..|| ... | |.  ...|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

LDYCPGGDLYAIITQSKH-----------------FRETQIA-----MVFQQIVSAVGYCHSRG-VAHRDLKPQNVLVTTFP---YIKISDFGLCGYINE
..||.||||  .|...|.                 | | |..       | ||...  |.|. . . |||.||.|.|..      ||||.|||.. ....
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

D----------------KRMKTFCGSPFFS----APECLKQVQYDG---KKSDIWSLGVILFELATGEHPWNPTNTPL----------------MIKQIT
.                ..|.||||.| .     |||.|.. .||.   .|.|||||||||.|. .|..| . .|                   ....| 
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

TASYQVPK--------GLNPACEDLIR----SLLKVRPNERPSCEQILQHPWL
   .|.||        ...| ..|.|.    ..||..||.|.. ||||.|||.
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 82761.m00546.AA ULK 13-265 29 5.7e-78 265.35 In-house 1-324 (324) Show / Hide 
Range on Protein: 13-265
Range on HMM: 1-324/324
Sequence Identity: 29% (95 aa)

YTLVEELGHGAFS-TVYAAKKKAD---VEIYAIKVIDIALVEKEGDK-------EHLQREIDVMAYLK---HEN--IVQLYDFFSDDVR--FFLVLDYCP
| | ..||.|.|  .|| ...| .    ...|.|.||.    |   .       . |..|| .|  ||   |.|  ||.|||.| ..    ......||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGDLYAIITQSKH---------FRETQIAMVFQQIVSAVGYCHSRGVAHRDLKPQNVLVTT-FPY-----------IKISDFGLCGYINED----KRMKT
||||  .| . |.         . | ..  .|.||...  . |.... |||.|||| |..  .|.           .||.|||..  ....      ..|
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

FC------GSPFFSAPECLK----QVQYDGKKSDIWSLGVILFELATGEHP---W-NPTNTPLMIKQ----------ITTASYQVPK-----GLNPACED
..      |.| . ||. |.    | .|. .|.||||||.|..|. .|. |   | |...   ..|           | .   | ||      . | |.|
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LIRSLLKVRPNERPSCEQILQHPWL
||| .|.. ...| | |.|..|||.
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 82761.m00546.AA ULK 13-265 29 4.7e-76 258.99 In-house 1-329 (329) Show / Hide 
Range on Protein: 13-265
Range on HMM: 1-329/329
Sequence Identity: 29% (97 aa)

YTLVEELGHGAFSTVYAAKKKAD----VEIYAIKVID---IALVEKEGD----KEHLQREIDVMAYLK--------HENIVQLYDFFSDDVR--FFLVLD
| | ..||.|.| .|| ...| .    .|..|.|.||   .   ..| .    .. |..||..|  ||        |.|||.|||.| ..    ......
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCPGGDLYAIITQSKH----------FRETQIAMVFQQIVSAVGYCHSRGVAHRDLKPQNVLVTT-FPY-----------IKISDFGLCGYINED----K
||.||||  .| . |.          . | ..  .|.||...  . |.... |||.||||.|..  .|.           .||.|||..  ...|    .
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

RMKTFC------GSPFFSAPECLK----QVQYDGKKSDIWSLGVILFELATGEHP---W-NPTNTPLMIKQ----------ITTASYQVPKG-----LNP
 |.|.       |.| . ||. |.    | .|. .|.||||||.|..|. .|. |   | |...   ..|           | .   | ||      . |
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

ACEDLIRSLLKVRPNERPSCEQILQHPWL
 |.|||| .|.. ...| | |....|||.
ECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 82761.m00546.AA CAMK-Unique 13-265 23 8.9e-75 246.23 In-house 1-363 (363) Show / Hide 
Range on Protein: 13-265
Range on HMM: 1-363/363
Sequence Identity: 23% (85 aa)

YTLVEELGHGAFSTVYAAKKKADVEIYAIKVIDIALVEKEGDKE-----------------HLQREIDVMAYLKHENIVQLYDF----FSDDV-------
|.... .|||.|. || .. ..   ..|.|..  . .. .  |.                  | ||....  ..|.||..|||.    | |.        
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------RFFLVLDYCPGGDLYAIITQ--------------------SKHFRE--TQIAMVFQQIVSAVGYCHSRGVAHRDLKPQNVLVTTFPY-----
        ....|..||.||||...| .                      || |  .... ..|...||| | || .. |||||. |..| . .      
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

-----------IKISDFGLCGYIN-EDKR--MKTFCGSPFFSAP--------------ECLKQVQYDGKKS---DIWSLGVILFELATGEHPWNPTNTP-
           ||..||||| ..|   ..  |.|.||.| . ||              | .... ||.. |   ||||||||......|..| .... . 
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------LMIKQITTASY-QVPKGLNPA-------CEDLIRSLLKVRPNERPSCEQILQHPWL
         .. |. . |  ...  .           |..  ...| |. | |....|.|.|.
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase 82761.m00546.AA STE 13-265 24 3.8e-72 246.0 In-house 1-359 (359) Show / Hide 
Range on Protein: 13-265
Range on HMM: 1-359/359
Sequence Identity: 24% (88 aa)

YTLVEELGHGAFSTVYAAKKKA---------------DVEIYAIKVIDIALVEK--------------EGDKEHLQREIDVMAYLK--HENIVQLYDFFS
....|..|.||| ||| |...                 .||.|||....   ..              . ... ...||..|  ..  |.|||. |. . 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DD-------VRFFLVLDYCPGGDLYAIITQS-KHFR-------------ETQIAMVFQQIVSA-VGYCHSRGVAHRDLKPQNVLVTTFPYIKISDFGLCG
..          .... |..|| |  || .  ....             |.||| . .||. .   | || .. |||.||.|.|.     .|..|||.||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

YINE-----------------DKRMKTFCGSPFFSAPECLKQ-----VQYDGKKSDIWSLGVILFELATGEHPW---NPTNTPLMIKQIT----------
 ...                 ... .||.|.| . ||| ..|     ..  . |.||||||  . |.|||..||   .|.   .|| . .          
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---TASYQVPKGLN-------------------PACEDLIRSLLKVRPNERPSCEQILQ--HPWL
     . . |  |                    | . | |.  |.  ||.||. .| |.  ||..
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 82761.m00546.AA Pkinase_Tyr 13-211 29 5.9e-22 74.99 Pfam 1-216 (270) Show / Hide 
Range on Protein: 13-211
Range on HMM: 1-216/270
Sequence Identity: 29% (65 aa)

YTLVEELGHGAFSTVYAAKKK----ADVEIYAIKVIDIALVEKEGDKEHLQREIDVMAYL-KHENIVQLYDFFS-DDVR--FFLVLDYCPGGDLYAIITQ
 |. ..||.||| .|| .. |     .    |.|..     ...  .| . ||. .|  | .|.|||.||   . ..     ..|. |.|.|||.    .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

----SKHFRETQIAMVFQQIVSAVGYCHSRGVAHRDLKPQNVLVTTFPYIKISDFGLCGYI--NEDK-RMKTFCGSPFF-SAPECLKQVQYDGKKSDIWS
     ...   ..    .|| ..  | .|..  ||||   |.|||    .||.||||. .|   .   |... .  | .  ||||..   .   |||.||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFT-TKSDVWS

LGVILFELAT-GEHP-W
 || ..|. | || | .
FGVLMWEIFTYGEQPTY
Kinase 82761.m00546.AA TyrKc 13-265 25 1.1e-17 62.95 SMART 1-280 (280) Show / Hide 
Range on Protein: 13-265
Range on HMM: 1-280/280
Sequence Identity: 25% (75 aa)

YTLVEELGHGAFSTVYAAKKKADVEIYAIKVIDIALVEKEGDKEHLQREIDVMAYL--KHENIVQLYDFFSDD-------VRFFLVLDYCPGGDLYAIIT
 || ..||.||| .|| .. |   .  |.|..          .| . ||. .|  |  .|.|||.||   ...          ..|. |.|.|||   . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

QSKH-FRETQIAMVFQQIVSAVGYCHSRGVAHRDLKPQNVLVTTFPYIKISDFGLCGYINED------KRMKTF----CG---SPFF-SAPECLKQVQYD
 ... .   .      || .   | ||... ||||   |.||.    .|||||||. .| .|      | ...     .|    |    ||||..   . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

GKKSDIWSLGVILFELATGEHPWNPT-----NTPLMIKQITTASYQVPKGLN----------PACEDLIRSLLKVRPNERPSCEQILQHPWL
  |||.|| || ..|. |   .  |       ..  . .   . |  |.  |          ..  .....  .  |..||. ..|  |  .
-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF