81839.m00120

Species: T.vaginalis
Alias: TvagK0518, 81839.m00120
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag2

Sequence

Name Sequence Type Origin Length Description Download
81839.m00120.AA Protein None 335 None Fasta, JSON
81839.m00120.kin_dom Protein Kinase Domain None 249 None Fasta, JSON

Protein domain

Protein domains of 81839.m00120.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 81839.m00120.AA S_TKc 21-269 30 1.4e-79 271.6 SMART 1-231 (231) Show / Hide
Range on Protein: 21-269
Range on HMM: 1-231/231
Sequence Identity: 30% (80 aa)

YTTQKLIGKGSYSVVAQAIDNKTNQVVACKVVSRKGITEAGYFYQLEKELRVLQSLNHPNIAQIYEVVYLEDIIIVVMEYCPN--GDLLDYITSKNG---
|.  ..||||....| .....||...||.|...           ....|...|.. .|||| ..|.| .  | . .|||||..  |||.||| ....   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LHPTEITEMLKQILSALVYLHSKGIAHRDLKPENIVLDEKFNLKLIDFGVCALTNSTHKTVVGSHLYIAPEVYFSQTYNPKLSDIWCLGVTIFVMKT
   ... ..  ...||..|| |.||.|| ||||||||| |||  ..|..|||....     .|..|.  |.||||     |... .|.| .|.... | .
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

ACFPWPEMNEMKLMSLIKQNSIPMPQVNVPILDKLLRACLVVSPEGRLSAAELYT---------LI
 . |.|  ...... .|.           . .| ..| ||.. || |..| |. .          .
GYPPFP--QMQMMFKKIG---------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Pkinase 81839.m00120.AA Pkinase 21-269 26 8.8e-73 252.9 Pfam 1-293 (293) Show / Hide
Range on Protein: 21-269
Range on HMM: 1-293/293
Sequence Identity: 26% (78 aa)

YTTQKLIGKGSYSVVAQAIDNKTNQVVACKVVSRKGITEAGYFYQLEK--ELRVLQSLNHPNIAQIYEVVYLEDIIIVVMEYCPNG----DLLDYIT--S
|.. . ||.||...| .... .|...||.|....... . .  ... .  |......|||||| ..|.... .| | .|||||..|    || |||.  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKS-WKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

KNGL--HPTEITEMLKQILSALVYLHSKGIAHRDLKPENIVLDEKFNL----KLIDFGVC----ALTNSTHKTVVGSHLYIAPEVYFSQTYNPKLSDIWC
....   . |.  ...|||..| |.||.|| ||||||||| .|.. ..    |..|||..       ||  .|..|.  |.||||  ...| .. .|.| 
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGVTIFVMKTACFPWPEM------NEMKLMSLIKQNSIPMPQVNV---------------------PILDKLLRACLVVSPEGRLSAAELYTL--I
.|.... | .  .|.|.       ..|... .|..  .. .  .                      . . .... || . |. |..|...     .
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 81839.m00120.AA CAMK 26-264 20 1.7e-72 232.67 In-house 1-418 (425) Show / Hide
Range on Protein: 26-264
Range on HMM: 1-418/425
Sequence Identity: 20% (84 aa)

LIGKGSYSVVAQAIDNKTN------------QVVACKVVSRKGITE-------------------------AGYFYQLEKELRVLQS-------LNHPNI
 .|.||...|  .|. .|.            | ||.|....| ...                         .    ....|......       |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

AQIYEVVYL-------------------EDIIIVVM---EYCPNG----DLLDYITSKNG---------------LHPTEITEMLKQILSALVYLHSKGI
 ..|||                      .. .. ||   |||..|    ||.|||... .               ..  |   . .||.||. |.||..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHRDLKPENIVLDEK-----------------FNLKLIDFGVCALTNS--------------------------THKTVVGSHLYIA-PEVYFS------
.||||||||| ||..                 .|.|.||||  .  ..                            ||..|.  |.| |||  .      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------QTYNPKLSDIWCLGVTIFVMKTACFPWPEM-------------NEMKLMSLIKQNSI--PMPQVNV----------------------PILDK
       ..| .. .|.| .||  ..| . ..|. .              |. .|.  |..     | |..                        .    
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LLRACLVVSPEGRLSAAE
|.| .|.| || |.....
LIRKMLQVDPEKRMTIEQ

Kinase 81839.m00120.AA CAMKL 21-265 30 3.5e-69 219.87 In-house 1-291 (297) Show / Hide
Range on Protein: 21-265
Range on HMM: 1-291/297
Sequence Identity: 30% (89 aa)

YTTQKLIGKGSYSVVAQAID-NKTNQVVACKVVSRKGITEAGYFYQ------------LEKELRVLQSLN---HPNIAQIYEVVYLEDI------IIVVM
|.  | .||||...|  |..   |.. || |.. .|.|..  .  .            ...| . ...||   |||| ..|||.. ..       |  ||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCPNGD--LLDYITSKNG----LHPTEITEMLKQILSALVYLHSKGIAHRDLKPENIVLDEKF--NLKLIDFGVCAL-T------NSTHKTVVGSHLYI
|||..|.  |.||| .. .    ... |   . .||.||. |.||.||.|||.||||| |||.   |.|.|||| ... .      . . ||  ||  | 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEVYFS--QTYNPKLSDIWCLGVTIFVMKTACFPWPEM--------NEMKLMSLIKQNSIPMPQVNVP-ILDKLLRACLVVSPEGRLSAAEL
|||.. .  . |. .  ||| .||. ..| .  .|. .         |  .|.  |..    .|  . .  .  |.|  |.| || | .. ..
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQI

Kinase 81839.m00120.AA STE 21-265 25 1.6e-59 204.08 In-house 1-351 (359) Show / Hide
Range on Protein: 21-265
Range on HMM: 1-351/359
Sequence Identity: 25% (92 aa)

YTTQKLIGKGSYSVVAQAIDN------KTNQV---------VACKVVS----RKGITE-----------AGYFYQLEKELRVLQSLN--HPNIAQIYEVV
.. .. ||||.. .| .|...      ||..|         .| |...    .. . |              . |..||..... .|  |||| . |   
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

YLE-------DIIIVVMEYCPNGDLLDYIT---SKNGLHP-----------TEITEMLKQILSA-LVYLHSKGIAHRDLKPENIVLDEKFNLKLIDFGVC
. |       | . ..|||...| | | |    .... ..           ..|  ...||| . | ||||..| |||.|| || |      ||.|||||
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVC

A-LTNS------------------THKTVVGSHLYIAPEVYFS------QTYNPKLSDIWCLGVTIFVMKTACFPWPEMNEMKLMSLIKQNS--------
. ||.|                    .|.||.  . ||||         . |. | .|||.|| ||  | | . || .|. |. | .| .|.        
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTK-CDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQ

-----IPMPQVNV----------------------PILDKLLRACLVVSPEGRLSAAEL
      | |.                         | .   .. ||.  |. | .| .|
LCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQL

Kinase 81839.m00120.AA ULK 21-261 24 2e-59 203.75 In-house 1-319 (329) Show / Hide
Range on Protein: 21-261
Range on HMM: 1-319/329
Sequence Identity: 24% (78 aa)

YTTQKLIGKGSYSVVAQAIDNKT----NQVVACKVVSRKGITEAGYFYQ-------LEKELRVLQSLN--------HPNIAQIYEVVYLEDI--IIVVME
|   . .||||. .| .....||    |..||||..... . .  . ..       |..| .... |.        |||| . |.. .  .   |  .||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCPNGDLLDYITSKNG----------LHPTEITEMLKQILSALVYLHSKGIAHRDLKPENIVLDEKFN------------LKLIDFGVCALTNST-----
||. ||| .||  ...          |   |. . .||||... .||...| |||.||.|| .....             ||. ||| .   ..      
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-HKTVV------GSHLYIAPEVYF----SQTYNPKLSDIWCLGVTIFVMKTACFP---W-PEMNEMKLMSL----------IKQNSIPMP-----QVNVP
  .| |      |. || ||..       . |. . .||| ||. .. | .   |   |  . .......|          ||.. .  |     ..  |
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

ILDKLLRACLVVSPEGRLS
 .  |.| .|.. .. | |
ECKDLIRRMLQYDEKDRIS

Kinase 81839.m00120.AA ULK 21-266 25 5.2e-59 202.36 In-house 1-319 (324) Show / Hide
Range on Protein: 21-266
Range on HMM: 1-319/324
Sequence Identity: 25% (82 aa)

YTTQKLIGKGSYS-VVAQAIDNKT---NQVVACKVVSRKGITEAGYFY-------QLEKELRVLQSLN---HPN--IAQIYEVVYLEDI--IIVVMEYCP
|   . .||||.  .| .....||   ||.||||....|.. .  . .       .|..| .... |.   |||  | . |.. .  .   |  .||||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGDLLDYITSKNG---------LHPTEITEMLKQILSALVYLHSKGIAHRDLKPENIVLDEKFN------------LKLIDFGVCALTNS-----TH-KT
 ||| .||  ...         |   |. . .|||.... .||...| |||.||.|| . ...             ||. ||| .   ..     .  .|
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

VV------GSHLYIAPEVYF----SQTYNPKLSDIWCLGVTIFVMKTACFP---WPEMNEM----KL-------MSLIKQNSIPMP---QVNV--PILDK
 |      |. || ||..       . |. . .||| ||. .. | .   |   |  ...     ||       . .||.. |. |   . ..  | .  
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LLRACLVVSPEGRLSAAELY
|.| .|.. .. | |  |..
LIRRMLQYDEKDRISWEEIF

Kinase 81839.m00120.AA Ciliate-E2 21-265 22 2.8e-55 188.23 In-house 1-359 (365) Show / Hide
Range on Protein: 21-265
Range on HMM: 1-359/365
Sequence Identity: 22% (84 aa)

YTTQKLIGKGSYSVVAQAIDNKT-----------------------NQVVACKVVSRKGITEAGYFYQLEKELR----------VLQSLNHPNIAQIYEV
|  .|.||.|....| .. . |.                       .. .| |... ..| .     .. .|..          .|..|||||| ..||.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VY--LEDIIIVVMEYCPNGDLLDYITSKNGLHPTEIT-----------EMLKQILS---------------ALVYLHSKG-IAHRDLKPENIVLDEKFNL
 .   .. |  |||||  |||.||| ...  .. ||.           .. ||||.               || |||||. | |||.|||||..     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLIDFGVCA----------------------------------LTNSTHKTVVGSHLYIAPEVYFSQTY--------NPKLSDIWCLGVTIFVMKTACFP
|.|||| .                                   .   ...|..|.  | |||.. .. |          . .|||.|||... | .  .|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

WPEMNEMKLMSLIKQNSIPMPQVN-------VPILD------------KLLRA----CLVVSPEGRLS-AAEL
.        .  |||. |  |. .       . ...             |..     .|.. || |.. . ..
F--------QQQIKQCKIDFPCPEWQKDTQCI-QCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQI

Kinase 81839.m00120.AA MARK 21-217 35 3.3e-55 178.99 In-house 1-206 (262) Show / Hide
Range on Protein: 21-217
Range on HMM: 1-206/262
Sequence Identity: 35% (74 aa)

YTTQKLIGKGSYSVVAQAIDNKTNQVVACKVVSRKGITEAGYFYQLEKELRVLQSLNHPNIAQIYEVVY--LEDI-IIVVMEYCPNGDLLDYITSK--NG
|   | ||.|||..|  |.. .|.. || |.. .. ...   .  .. |......|.|||| . ..|.    |   | ..|||...|.|.||| ..    
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LHPTEITEMLKQILSALVYLHSKGIAHRDLKPENIVLDEKF--NLKLIDFGVCALT--NSTHKTVVGSHLYIAPEVYFSQTYNPKLSDIWCLGVTIFVMK
||  |   . .||.||. |.|||.|.|||.||||| .||.   | |.|||| ..    ..  .|  |.  | |||.  .. |. .  ||| |||  ..| 
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

TACFPW
. .||.
CGYFPF

Kinase 81839.m00120.AA MELK 21-265 36 2.8e-53 180.31 In-house 1-248 (254) Show / Hide
Range on Protein: 21-265
Range on HMM: 1-248/254
Sequence Identity: 36% (91 aa)

YTTQKLIGKGSYSVVAQAIDNKTNQVVACKVVSRKGITEAGYFYQLEKELRVLQSLNHPNIAQIYEVVYLEDIIIVVMEYCPNGDLLDYITSKNGLHPTE
|   . || | .. |  |    ||| || |.. .. . .   . ... |.  |..| | .| |.| ..  || | .|||||| |...||| ... |.  |
YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQLGHD--LPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEE

ITEMLKQILSALVYLHSKGIAHRDLKPENIVLDEKFNLKLIDFGVCALT---NSTH--KTVVGSHLYIAPEVYFSQTYNPKLSDIWCLGVTIFVMKTACF
   ...||.||. |.||.| |||||||||...||...|||||||.|| |      |  .|  ||  | |||.   . |     |.| .|. ..|.     
TRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFL

PWPEMNEMKLMSLIKQNSIPMPQVNVPILDKLLRACLVVSPEGRLSAAEL
|. . | | .   | .     |.   |   .|||. | | |. |.|  .|
PFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNL

Kinase 81839.m00120.AA Ciliate-E2-Unclassified 21-265 22 5e-52 178.75 In-house 1-346 (352) Show / Hide
Range on Protein: 21-265
Range on HMM: 1-346/352
Sequence Identity: 22% (77 aa)

YTTQKLIGKGSYSVVAQAIDNKTNQVV-----ACKVVSRK-GITEAGYFYQLEKELRVLQS----------------LNHPNIAQIYEVVYLEDI--IIV
|. .| ||.|....| .....|..  .     ..|. ..|  . .      . ..... .                 ||||..  .... . .|   |. 
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VMEYCPNGDLLDYITSKNG-----------------LHPTEIT-----EMLKQILSALVYLHSKG-IAHRDLKPENIVLDEK---FNLKLIDFGVCALTN
|||||..|||..||.....                 .   ..       ...|||..| |||.|. | |||.|||||..|..   ...|.|||| .   .
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

ST------------------HKTVVGSHLYI----APEVYFSQTYNP---KLSDIWCLGVTIFVMKTACFPWPEMNEMK----------------LMSLI
.                    .|..|.  |.    ||||. .| |.    . .|||.||| .. | .  .| .  |. .                | . |
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

KQNSIPMPQVNV----PILD--------KLLRACLVVSPEGRLSAAEL
||. |  |  .      ...        .||. .|.. |. |... ..
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQI

Kinase 81839.m00120.AA CAMK-Unique 21-210 23 8.7e-51 165.77 In-house 1-286 (363) Show / Hide
Range on Protein: 21-210
Range on HMM: 1-286/363
Sequence Identity: 23% (68 aa)

YTTQKLIGKGSYSVVAQAIDNKTNQVVACKVVSRKGITEAGYFYQ-----------------LEKELRVLQSLNHPNIAQIYEV----VYLED-------
|.. ..||.|....|  ..| .|    |||.|  ..  .  .  |                 |..|........|||| ..|..    .  ..       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------IIIVVMEYCPNGDLLDYITS--------------------KNGLHP--TEITEMLKQILSALVYLHSKGIAHRDLKPENIVLDEKFN-----
         .  |||||. |||.|.| .                    .  .    ....    ..|||. |.||..| |||||.|||.. . |.     
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

-----------LKLIDFGVCALTNSTHKT-----VVGSHLYIAP--------------EVYFSQTYNPKLS---DIWCLGVTIFVM
           .||.||| |.. |. ..      ..|. .|.||              ||   | |  ..|   ||| |||. . |
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYM

Kinase 81839.m00120.AA Pkinase_Tyr 21-145 31 4e-21 72.16 Pfam 1-137 (270) Show / Hide
Range on Protein: 21-145
Range on HMM: 1-137/270
Sequence Identity: 31% (43 aa)

YTTQKLIGKGSYSVVAQAIDN----KTNQVVACKVVSRKGITEAG-YFYQLEKELRVLQSL-NHPNIAQIYEVVY-LEDI--IIVVMEYCPNGDLLDYIT
 |  | .|.|.. .| ... .    .|.. || |.. . | ..   .   . .|.... .| .|||| . | |..  ..   |..||||.|.||||||  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

S----KNGLHPTEITEMLKQILSALVYLHSKGIAHRDL
.    |. | . .. .|  || ... ||.||.. ||||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL

Kinase 81839.m00120.AA TyrKc 21-269 23 2.1e-18 68.39 SMART 1-280 (280) Show / Hide
Range on Protein: 21-269
Range on HMM: 1-280/280
Sequence Identity: 23% (67 aa)

YTTQKLIGKGSYSVVAQAIDNKTNQVVACKVVSRKGITEAGYFYQLEKELRVLQSL--NHPNIAQIYEVVYLE-------DIIIVVMEYCPNGDLLDYIT
 |  | .| | . .| ... .   . || |..             . .|.|.. .|  .|||| ..| |.  .       . . .||||.|.|||.||. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

SKNG-LHPTEITEMLKQILSALVYLHSKGIAHRDLKPENIVLDEKFNLKLIDFGVCALTNST------HKTVV-----GSH--L---YIAPEVYFSQTYN
.. . | . .  ..  || .   |||||.. ||||   |. ..|..  |  ||| .    .       ... .     |..  |     |||. .  ...
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

PKLSDIWCLGVTIF-VMKTACFPWPE-----MNEMKLMSLIKQNSIPMPQVN---------VPILDKLLRACLVVSPEGRLSAAELYTLI
.| ||.|  ||... ..     |.|.     |.   .. ..||   ...  |          . . .. . |    || | . .|.. ..
TK-SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF