Gene 95287.m00267 (T.vaginalis)

95287.m00267

Species: T.vaginalis
Alias: TvagK0691, 95287.m00267
External Links:
Annotation:

Classification

Group: Other
Family: NEK
Subfamily: NEK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
95287.m00267.AA Protein None 815 None Fasta, JSON
95287.m00267.kin_dom Protein Kinase Domain None 255 None Fasta, JSON

Protein domain

Protein domains of 95287.m00267.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 95287.m00267.AA NEK 6-260 47 3.5e-156 525.16 In-house 1-286 (286) Show / Hide 
Range on Protein: 6-260
Range on HMM: 1-286/286
Sequence Identity: 47% (137 aa)

YTVKKVIGEGAYGRAVLCVEKASGEY-----CVIKEIAMANLSAQEQKDAK-KEVKILSSLHHPNIIGYRTSFNAKN--VLHIVMDYAD-NGDLFTQ---
|.. |.||.|..|.. ..  |  |       .|.|.| | |.| .|...|  .||.||..|.||||..|. ||  ..   |.|||.|.. .|||. .   
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

IQNAR--GVHFKEDQILDWFVQICLALKHIHDR-----KILHRDIKCQNIFLMKNGM----IKMGDFGIAKILDHTTQLSKT-AIGTPYYLSPEICEGKA
|.. .  | .| |.||.|||.|.|||||..|||     ||||||||.||||| ||..    .|.|||||.|.|.|||.. .|  .|||||.|||.|..| 
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKP

YNSKSDIWSLGCVLYELCTL--NHAFDAN--CMNGLIMKILRS-KHAPIPYY--YSQPLRSLVDSLLNKDAKKRPSINQILKLDFI
||.|||||||||||||.|||  .|.|.|.   |..|.||| .  . .||| .  ||| |..|. ..|.|| ..|||.||||.. ||
YNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase 95287.m00267.AA NEK1 6-260 51 8.8e-153 513.87 In-house 1-276 (276) Show / Hide 
Range on Protein: 6-260
Range on HMM: 1-276/276
Sequence Identity: 51% (141 aa)

YTVKKVIGEGAYGRAVLCVEKASGEYCVIKEIAMANLSAQEQKDAKKEVKILSSLHHPNIIGYRTSFNAKNV--LHIVMDYADNGDLFTQIQNA--RGVH
|...|.||||..|.|.|  .|..|  .|||||   . . .|  ....||.||. . ||||..|. || .     | |||.|.|.|||.  |...  .|. 
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGKL

FKEDQILDWFVQICLALKHIHDRKILHRDIKCQNIFLM--KNG---------------MIKMGDFGIAKILDHTTQLSKTAIGTPYYLSPEICEGKAYNS
| ||||..||.||||||.||||||||||||| |||||   |||               ..|.||||||..| ||. . .| ||||||||||||. | || 
FSEDQIMHWFCQICLALNHIHDRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPEICQNKPYNN

KSDIWSLGCVLYELCTLNHAFDANCMNGLIMKILRSKHAPIPYYYSQPLRSLVDSLLNKDAKKRPSINQILKLDFI
||||||||||||||||| |.|.|| .  |..||...  .|||  ||. |.||| ........ |||.||||.  ||
KSDIWSLGCVLYELCTLKHPFEANNWKNLVLKICQGTYPPIPPHYSYELQSLVSQMFKRNPRHRPSVNQILERPFI
Kinase 95287.m00267.AA NEK8 6-260 40 6e-124 355.8 In-house 1-278 (278) Show / Hide 
Range on Protein: 6-260
Range on HMM: 1-278/278
Sequence Identity: 40% (112 aa)

YTVKKVIGEGAYGRAVLCVEKASG--EYCVIKEIAMANLSAQEQKDAKKEVKILSSLHHPNIIGYRTSFNAKNVLHIVMDYADNGDLFTQIQNARG-VHF
|.   |.| || | ..|.  |. .     ..|.| |  .|  |  .|  |. .|| |.|||||.|  .|   |.| |.| ||| | |   ||  ..  ..
YERIRVVGRGAFGICWLYRRKEDQSHHLVIWKQINMHRMSEKERQMAQNEIQVLSMLQHPNIISYYDHFMEDNTLMIEMEYADGGTLYQMIQHQQNKLFE

KED----------------QILDWFVQICLALKHIHDRKILHRDIKCQNIFLMKN-GMIKMGDFGIAKILDHTTQLS--KTAIGTPYYLSPEICEGKAYN
 |                 .||. |.|.|.|. |.|.  |||||.| ||||. .  . .| |||||.||.   .  .  || .|||||.|||.|||| ||
EERQLKQVNHCFNIYFNEQMILWYFFQMCSAVHHMHQHNILHRDLKTQNIFMTRHRMVVKIGDFGISKIMNTKYHMQTTKTVVGTPYYMSPEMCEGKPYN

SKSDIWSLGCVLYELCTLNHAFDANCMNGLIMKILRS-KHAPIPYYYSQPLRSLVDSLLNKDAKKRPSINQILKLDFI
 |||.|.|||||||.|.|  ||.|     |..|| .. ...||.  ||  .|.|| ..| .|. .|||  ||..   .
QKSDMWALGCVLYEMCCLKRAFEASNLPALVWKIMQCRAYEPISDHYSNEMRMLVHNCLQQDPEQRPSASQIMAMPLC
Kinase 95287.m00267.AA NEK4 6-260 44 5.70000000001e-108 365.0 In-house 1-257 (257) Show / Hide 
Range on Protein: 6-260
Range on HMM: 1-257/257
Sequence Identity: 44% (115 aa)

YTVKKVIGEGAYGRAVLCVEKASGEYCVIKEIAMANLSAQEQKDAKKEVKILSSLHHPNIIGYRTSFNAKNV--LHIVMDYADNGDLFTQIQNARGVHFK
|   ||.| | ||   |  ..  .   |.| . . | | .|.|.| .|...|| | ||||. |  |.   |   | ||| . . |||... .  ..   .
YCHMKVVGKGSYGEVWLVRHRRDKKQYVMKKMFLKNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRKLKQQKNQFLE

EDQILDWFVQICLALKHIHDRKILHRDIKCQNIFLMKNGMIKMGDFGIAKILDHTTQLSKTAIGTPYYLSPEICEGKAYNSKSDIWSLGCVLYELCTLNH
| |...||||| .||  .|...||||| | ||||| |  .||.|||||...|.   .. || ||||||.|||.   ..|. ||||||||| .||. || |
EYQVVEWFVQIAMALQYMHEKHILHRDLKTQNIFLTKKNIIKIGDFGISRVLNNHCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSLGCCVYEMITLKH

AFDANCMNGLIMKILRSKHAPIPYYYSQPLRSLVDSLLNKDAKKRPSINQILKLDFI
||||  || || .|.  .  |.|  ||| |  ||  .|.|  .||||| .|..  .|
AFDAKDMNSLIYQIIQGQPPPMPPNYSQDLQNLVYQMLEKQPTKRPSIFDIFQMPYI
Kinase 95287.m00267.AA S_TKc 6-260 30 6.3e-91 309.29 SMART 1-231 (231) Show / Hide 
Range on Protein: 6-260
Range on HMM: 1-231/231
Sequence Identity: 30% (81 aa)

YTVKKVIGEGAYGRAVLCVEKASGEYCVIKEIAMANLSAQEQKDAKKEVKILSSLHHPNIIGYRTSFNAKNVLHIVMDYADN--GDLFTQIQNARGVH--
|.. ..||.||.|.  .|..| .|... ||.|          .....|..||.. |||||. .  .|   . |..||.|.|.  ||||. |.. ..    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--FKEDQILDWFVQICLALKHIHDRKILHRDIKCQNIFLMKNGMIKMGDFGIAKILDHTTQLSKTAIGTPYYLSPEICEGKAYNS-KSDIWSLGCVLYEL
  | | ..  .. |||.||...|...|.|||.| .||.| .   || .|||.|..|       .| .|||.|..||..    |.  |.|.||.||.|||.
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

CTLNHAFDANCMNGLIMKILRSKHAPIPYYYSQPLRSLVDSLLNKDAKKRPSINQILK-------LDFI
..    |.      ...|...          |........ .|.|| .|||.. ..|.         ..
LCGYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 95287.m00267.AA Pkinase 6-260 28 4.6e-81 280.4 Pfam 1-293 (293) Show / Hide 
Range on Protein: 6-260
Range on HMM: 1-293/293
Sequence Identity: 28% (84 aa)

YTVKKVIGEGAYGRAVLCVEKASGEYCVIKEIAMANLSAQEQKDAKK--EVKILSSLHHPNIIGYRTSFNAKNVLHIVMDYADNG----DLFTQIQNARG
|.....||.|..|.  .|..| .|.  ..|.|   . . .... . .  |..|. .|.||||. .. .|  |. ...||.|...|    |||. |.  |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

VHF--KEDQILDWFVQICLALKHIHDRKILHRDIKCQNIFLMKNGMI----KMGDFGIAKIL-DHTTQLSKTAIGTPYYLSPEICE-GKAYNSKSDIWSL
  |   |... ... ||. .|...|...|.|||.| .||.. .|| |    | .|||.|| .     .  .|  |||.|..||..  |. | .|.|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCVLYELCTLNHAFDAN------CMNGLIMKILR-SKHAPIPYYYS-------------------QPLRSLVDSLLNKDAKKRPSINQILKLDFI
||.|||... .  |.        ... .| .|..   | ..|. .|                   ..........|.|| ||||.. |||. ...
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 95287.m00267.AA NEK-Unclassified 56-260 40 5.5e-74 244.27 In-house 46-258 (258) Show / Hide 
Range on Protein: 56-260
Range on HMM: 46-258/258
Sequence Identity: 40% (86 aa)

ILSSLHHPNIIGYRTSFNAKNVLHIVMDYADNGDLFTQIQNARGV--HFKEDQILDWFVQICLALKHIHDRKILHRDIKCQNIFLMKNGMIKMGDFGIAK
||| | || |. |  ||     |    || | |.|   ||  |.    | |  |  |..|.  |.  || |||.||| | ||||| .  .. ||||||..
ILSQLRHPHIVTYHDSFFENAKLFYTQDYCDGGNLDRRIQKHRKKNEPFDEGRIMQWCIQMIMAVQYIHQRKIIHRDLKPQNIFLTDDDTVSMGDFGISR

ILDHTTQLSKTAIGTPYYLSPEICEGKAYNSKSDIWSLGCVLYELCTLNHAFDANCMNGLIMKILRSKH------APIPYYYSQPLRSLVDSLLNKDAKK
|.|||    .| .||. ..|||.|. . || .||.|||||..||.||   .||.  |  . ||| .          |.   ||  |  ..  .| ..  .
IMDHTRDKARTCVGTMCWMSPEVCQDQPYNNRSDVWSLGCIIYEMCTCEPFFDTHNMGEVYMKIKQDDNRLEEALEPVSKTYSTDLQQVIRFMLRRNFQQ

RPSINQILKLDFI
|||   |. .|.|
RPSATEIVEQDYI
Kinase 95287.m00267.AA CAMK 11-260 20 1.8e-72 232.66 In-house 1-425 (425) Show / Hide 
Range on Protein: 11-260
Range on HMM: 1-425/425
Sequence Identity: 20% (86 aa)

VIGEGAYGRAVLCVEKASG------------EYCVIKEIAMANLS--------------------------AQEQKDAKKEVKILSS-------LHHPNI
..|.|..|   ||..| ..            . . || |    |.                          .. .|  ..|..|...       |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IGYRTSFN------------AKNV--------LHIVM---DYADNG----DLFTQIQNARG-------------VHFKEDQILDWFVQICLALKHIHDRK
|     .               .         ...||   .|...|    |||  |.  ..              .|.|..   .| ||| |....|...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

ILHRDIKCQNIFLMKN-----------------GMIKMGDFGIAKILDH-----------------------TTQLSKTAIGTPYYLS-PEICEG-----
| |||.|. || | .|                 . ||  ||| |...|.                       ..|. ||  |||.| . ||. .|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------KAYNSKSDIWSLGCVLYELCTLNHAFDAN-------------CMNGLIMKILRSKHAPIPYY-----------------------YSQPLR
         . |. |.|.||.|..|| . .    |..              ... |  ||.. |   .|.|                        ||  .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

SLVDSLLNKDAKKRPSINQILKLDFI
.|. ..|..| .||..| |.|.  ..
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 95287.m00267.AA STE 6-260 24 1.1e-65 224.49 In-house 1-359 (359) Show / Hide 
Range on Protein: 6-260
Range on HMM: 1-359/359
Sequence Identity: 24% (88 aa)

YTVKKVIGEGAYGRAVLCVEK------ASGEY---------CVIKEIAMANLSA---------------QEQKDAKKEVKILSSLH--HPNIIGYRTSFN
..  ..||.||.|  .... .       .||          . ||.. . | ..               .|... .||.||.. ..  ||||. |  .. 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

AK-------NVLHIVMDYADNGDLFTQIQNARGV------------HFKEDQILDWFVQICLA-LKHIHDRKILHRDIKCQNIFLMKNGMIKMGDFGIAK
 .       . |.|.| | |.| |   |..  |.            .|.|.||    .||. . |...|. .| |||||..||.|     .|  |||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

ILDH---------------TTQ-LSKTAIGTPYYLSPEICEG------KAYNSKSDIWSLGCVLYELCTLNHAF-DANCMNGLIMKILR-----------
.|..               |.|  ..| .||| . .||. ..      | |. |.|||||||.. |..| .. . | . |  . |..             
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---SKHAPIPYY-------------------YSQPLRSLVDSLLNKDAKKRPSINQILK--LDFI
    .. |.|                     .|....  ..  |.|| .|||. .| ||    ||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 95287.m00267.AA NEK11 6-260 37 7.1e-65 221.85 In-house 1-259 (259) Show / Hide 
Range on Protein: 6-260
Range on HMM: 1-259/259
Sequence Identity: 37% (97 aa)

YTVKKVIGEGAYGRAVLCVEKAS---GEYCVIKEIAMANLSAQEQKDAKKEVKILSSLHHPNIIGYRTSFNAKNVLHIVMDYADNGDLFTQIQNAR--GV
| ... .| |..|   |  .|      |  |.|||..  |   |   |  | ..|| |||| |. .  ||  ..   |. .| .  ||  .||  .  | 
YVLQQKLGSGSFGTVYLVSDKKAKRGEELKVLKEISVGELNPNETVQANVEAQLLSRLHHPAIVRFHASFMEQDNFCIITEYCEGRDLDYRIQEYKQAGK

HFKEDQILDWFVQICLALKHIHDRKILHRDIKCQNIFLMKNGMIKMGDFGIAKILDHTTQLSKTAIGTPYYLSPEICEGKAYNSKSDIWSLGCVLYELCT
 | | ||..||.|. |    .|.|.|||||.| .|||| || ..|.||||....|    .|  |  ||| |.|||    . | .||||||| |.|||.| 
IFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNIFL-KNNLLKIGDFGVSRLLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCC

LNHAFDANCMNGLIMKILRSKHAPIPYYYSQPLRSLVDSLLNKDAKKRPSINQILKLDFI
..|||       ....|   .   .|  | . | ......|||.   |||  .|||  ..
MDHAFAGSNFLSIVLNIVEGDTPSLPDRYPRELNTIMERMLNKNPSLRPSAIDILKIPYM
Kinase 95287.m00267.AA NEK2 6-260 32 8.7e-63 210.22 In-house 1-319 (319) Show / Hide 
Range on Protein: 6-260
Range on HMM: 1-319/319
Sequence Identity: 32% (104 aa)

YTVKKVIGEGAYGRAVLCVEKASGEYCVIKEIAMANLSAQEQKDAKKEVKILSSLHHPNIIGY--RTSFNAKNVLHIVMDYADNGDLFTQIQNARGVH--
| | ..||.| .||      |  |.  | |||   ..   |      |. ||. | ||||. |  .    .. .| ||| |   |||   |. .|  .  
YEVLYTIGNGSFGRCRKVRRKSDGKILVWKEICYGHMQEKECQMLVSECNILRQLKHPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIKKCRKERQY

FKEDQILDWFVQICLALKHIHD---------------------RKILHRDIKCQNIFLMKNGM-------------------------------------
. |  |.  . |.|.||. .|                      . |||||||  ||||  ..                                      
MEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHTILHRDIKPANIFLDYDHNDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQ

--IKMGDFGIAKILDHTTQLSKTAIGTPYYLSPEICEGKAYNSKSDIWSLGCVLYELCTLNHAFDANCMNGLIMKILRSKHAPIPYYYSQPLRSLVDSLL
  .| |||| |..| | |.  .| .||||| |||  .|  || ||||||.||..||.|.|   | |     |  ||   .  .|||.||. |  .. . .
VVVKLGDFGLARMLNHDTSFAHTFVGTPYYMSPEQMHGQKYNEKSDIWSVGCLIYEMCALHPPFQATNQAQLQEKIKQGHFRRIPYQYSRHLNEIIHFMI

NKDAKKRPSINQILKLDFI
| | ..||||. ||.  .|
NVDHYHRPSIEEILQHPQI
Kinase 95287.m00267.AA ULK 6-260 24 1.1e-61 211.29 In-house 1-329 (329) Show / Hide 
Range on Protein: 6-260
Range on HMM: 1-329/329
Sequence Identity: 24% (81 aa)

YTVKKVIGEGAYGRAVLCVEKAS----GEYCVIKEIAMANLSAQEQKDA--------KKEVKILSSLH--------HPNIIGYRTSFNAK--NVLHIVMD
| .....|.|..|.      | .    .|....| |    .. ... .         |.|.||.  |.        ||||. .   |. .  | . |.|.
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YADNGDLFTQIQNARG--------VHFKEDQILDWFVQICLALKHIHDRKILHRDIKCQNIFLMKN------------GMIKMGDFGIAKILDHT---TQ
| . |||.. |.. ..         .. |....  | ||. ..|..|...| ||||| ||| . ..            | .| .||| || .|      |
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

LSKTAI------GTPYYLSPEICE----GKAYN-SKSDIWSLGCVLYELCTLNHAFDANCMNGLI-MKILRSKH-----------APIPYY-------YS
. .|.       |||.| .|.| .    .| |. .|.|||||||..||. .    | |.  | .. ..| . .             |. ..        |
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

QPLRSLVDSLLNKDAKKRPSINQILKLDFI
. ...|   .| .| |.| |. ....  ..
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 95287.m00267.AA TyrKc 6-260 19 1.4e-21 78.97 SMART 1-280 (280) Show / Hide 
Range on Protein: 6-260
Range on HMM: 1-280/280
Sequence Identity: 19% (57 aa)

YTVKKVIGEGAYGRAVLCVEKASGEYCVIKEIAMANLSAQEQKDAKKEVKILSSL--HHPNIIGYRTSFNAK-------NVLHIVMDYADNGDLFTQIQN
 | .|..||||.|. .... |   . . .| .         ..|  .| .|...|  |||||.        .         | ||| |...|||   ...
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

ARGVHFKEDQILDWFVQICLALKHIHDRKILHRDIKCQNIFLMKNGMIKMGDFGIAKILDHT--------TQLSKTAIGTP-----YYLSPEICEGKAYN
 |.  .. .. |.. .||.    ..|.... |||. . |. . .|. .| .||| .. ...         .  .|.  |.        ..||    . ..
HRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

SKSDIWSLGCVLYELCTLNHAFDAN-----CMNGLIMKILRSKHAPIPYYY---------SQPLRSLVDSLLNKDAKKRPSINQILKLDFI
.|||.|| | ...|..|.      .     . |  ... ... . . .  .         .. . ..  .  . |...||. ..|   ...
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 95287.m00267.AA Pkinase_Tyr 80-201 24 1.1e-16 57.18 Pfam 84-210 (270) Show / Hide 
Range on Protein: 80-201
Range on HMM: 84-210/270
Sequence Identity: 24% (31 aa)

IVMDYADNGDLFTQIQNA--RGVHFKEDQILDWFVQICLALKHIHDRKILHRDIKCQNIFLMKNGMIKMGDFGIAKIL---DHT-TQLSKTAIGTPYYLS
||| |. .||| .  ..    . ...  ..|.. .||. .. . ..... |||. . |. . .|. .| .||| |. .   |   .. ... .  . . .
IVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWM-A

PEICEGKAYNSKSDIWSLGCVLYELCTL
||    . ...|||.|| | ...|..|.
PECINYGKFTTKSDVWSFGVLMWEIFTY
Kinase 95287.m00267.AA Pkinase_Tyr 6-66 27 2e-06 22.19 Pfam 1-67 (270) Show / Hide 
Range on Protein: 6-66
Range on HMM: 1-67/270
Sequence Identity: 27% (19 aa)

YTVKKVIGEGAYGRAVLCVEK----ASGEYCVIKEIAMANLSAQE--QKDAKKEVKILSSL-HHPNII
 |  |..||||.|. .... |      .  . .| .   . . ..  ..|  .|.||...| |||||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIV