97466.m00041

Species: T.vaginalis
Alias: 97466.m00041, TvagK0135
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: AMPK

Sequence

Name Sequence Type Origin Length Description Download
97466.m00041.AA Protein None 339 None Fasta, JSON
97466.m00041.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of 97466.m00041.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 97466.m00041.AA AGC 28-266 21 7.1e-97 250.35 In-house 16-395 (395) Show / Hide
Range on Protein: 28-266
Range on HMM: 16-395/395
Sequence Identity: 21% (84 aa)

YKARHN------KTGAIVVIKVLPNSN-NSHRRN-VYDHA-HE------------IQIMKMLD----------HPLTVD-FYDAFSDDER--TYIVMEYL
| .|..       || .  .|||  .     ..    .|.  |             .|.....          ||  |   . .| |...   |.||||.
YLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSFQDKDHTYLYFVMEYM

P---------RG-SLFEYIL---QNGKLSEQISNNIFTQ-------LISAIDYLHNELHIVHRD-IKAENVLLDQNFNVRLIDFGLAGRISKIF------
|          |  || ..    ..|...|. .  .. .       ...|..|||....|.||| .| ||.|||.. ...| ||||. .. .        
PRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQS

-------------------------------------------PKLDFS-CG--SIGYMAPEIFSGHGYDEQVDIWS--TGVLLFALLTGYLPFSGQNSS
                                            ..  . ||  .  ||||||.    |. ..|.||   |.|.. .|||| ||.|.|  
QSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQ

----------DIKHNIL------HQNIEFP----------DYLSKDAKNLLSKMLERNPTKRIS----------IQGIKQHSWF
          .. ..|.      .....||          ...|..||.|..|.|...|.||.           .. ||.| ||
ENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF

Kinase 97466.m00041.AA CAMKL 30-266 35 9.4e-94 299.57 In-house 18-297 (297) Show / Hide
Range on Protein: 30-266
Range on HMM: 18-297/297
Sequence Identity: 35% (101 aa)

ARH-NKTGAIVVIKVLPNSNNSHRRNVYDHAH------------EIQIMKMLD---HPLTVDFYDAFSDDER------TYIVMEYLPRGS--LFEYILQN
|.|   ||  | ||..  .  . . .. ..              ||||||||.   ||  . .|. . ..|        |.|||| . |.  ||.|| ..
ATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKH

----GKLSEQISNNIFTQLISAIDYLHNELHIVHRDIKAENVLLDQNF--NVRLIDFGLAGRISKI----FPKLDFSCGSIGYMAPEIFSG--HGYD-EQ
    |...|     .|.|..||..|.|.   |||||||.||.|||.|   |. .||||..  . ..      ||. .|||  |||||||.|    ||  .
GHRRGRMPEHEARRYFRQIVSAVNYCHSHG-IVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPK

VDIWSTGVLLFALLTGYLPFSGQ--------NSSDIKHNILHQNIEFP--DYLSKDAKNLLSKMLERNPTKRISIQGIKQHSWF
||||| ||.|.|...||||| ..        |    .. |  .  ..|   ..| |...|..|||..||.||..|. |..| |.
VDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM

Kinase 97466.m00041.AA CAMK 26-266 22 8.7e-91 292.71 In-house 9-425 (425) Show / Hide
Range on Protein: 26-266
Range on HMM: 9-425/425
Sequence Identity: 22% (93 aa)

TIYKARHNKTG------------AIVVIKVLP----------------------NSNNSHRRNVYDHA---HEIQIMKM-------LDHPLTVDFYDAFS
. ....| .|.              | ||...                      ..... .|. .| .   .||.|||.       ||||  . .|... 
KVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYE

D-------------------DERTYIVM---EYLPRG----SLFEYILQN---------------GKLSEQISNNIFTQLISAIDYLHNELHIVHRDIKA
|                   |.. |.||   || . |     ||.|| ..               |...|.    .| |..||..|.|.   |||||.| 
DPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN-IVHRDLKP

ENVLLDQN-----------------FNVRLIDFGLAGRISKI-----------------------FPKLDFSCGSIGYMA-PEIFSG-------------
||.|||.|                 .|. .||||.| .. .                         .|.  .||. .||| ||...|             
ENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEE

-HGYDEQVDIWSTGVLLFALLTGYLPFSGQ-------------NSSDIKHNILHQNIEFPDY------------------------LSKDAKNLLSKMLE
  .|....|.|| ||.|...|.||.|| |              | ......|.  . .||..                        .|...|.|..|||.
KPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQ

RNPTKRISIQGIKQHSWF
..|.||..|. ...| |.
VDPEKRMTIEQCLNHPWM

Kinase 97466.m00041.AA MARK 13-266 36 2.5e-88 288.82 In-house 1-262 (262) Show / Hide
Range on Protein: 13-266
Range on HMM: 1-262/262
Sequence Identity: 36% (97 aa)

YTVLEIIDQSVHRTIYKARHNKTGAIVVIKVLP---NSNNSHRRNVYDHAHEIQIMKMLDHPLTVDFYDAFS--DDER-TYIVMEYLPRGSLFEYILQN-
| .|  | .  . . ..|.| .||  | ||...    . .  ..||.    ||.|||.||||  . .....   . .. .|..||| ..|.|..|| .  
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVM---REIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHP

-GKLSEQISNNIFTQLISAIDYLHNELHIVHRDIKAENVLLDQNF--NVRLIDFGLAGRISKIFPKLDFSCGSIGYMAPEIFSGHGYD-EQVDIWSTGVL
 |.|.|     ||.|..||. |.|.   |||||||.||.|.|.|   |. .||||.. .. .   ||.  ||.  |||||||..  ||   ||||| ||.
NGRLHEEEARRIFRQIVSAVNYCHSKN-IVHRDIKPENILIDENGNHNIKIIDFGFS-ICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVV

LFALLTGYLPFSGQN--SSDIKHNILHQNIEFPDYLSKDAKNLLSKMLERNPTKRISIQGIKQHSWF
|.....||.|| |..    ... .||. . ..|...||...||....|  || .|..|. | .|.|.
LYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase 97466.m00041.AA S_TKc 13-266 32 1.1e-84 288.56 SMART 1-231 (231) Show / Hide
Range on Protein: 13-266
Range on HMM: 1-231/231
Sequence Identity: 32% (89 aa)

YTVLEIIDQSVHRTIYKARHNKTGAIVVIKVLPNSNNSHRRNVYDHAHEIQIMKMLDHPLTVDFYDAFSDDERTYIVMEYLPR--GSLFEYILQNGK---
|..|..| .    . ||.||.||| || ||...           .   ||||.|. .||  | .||.| | .. |.||||..   |.||.|| ..|.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LSEQISNNIFTQLISAIDYLHNELHIVHRDIKAENVLLDQNFNVRLIDFGLAGRISKIFPKLDFSCGSIGYMAPEIFSGHGYDE-QVDIWSTGVLLF
   ..|     .. |...|..|.|.  .|.|||.| ||.|||.  .. ..||||| ..       .  ||.  |||||..   ||.   .|.|| |..|.
RFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ALLTGYLPFSGQNSSDIKHNILHQNIEFPDYLSKDAKNLLSKMLERNPTKRISIQGIKQ-------HSWF
 .|.|| ||.  .   . ..|.          |..||....|.|...|.||...  . |       | ||
EMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 97466.m00041.AA AMPK 30-266 39 5.7e-84 249.19 In-house 18-254 (254) Show / Hide
Range on Protein: 30-266
Range on HMM: 18-254/254
Sequence Identity: 39% (95 aa)

ARHNKTGAIVVIKVLPNSNNSHRRNVYDHAHEIQIMKMLDHPLTVDFYDAF-SDDERTYIVMEYLPRGSLFEYILQNGKLSEQISNNIFTQLISAIDYLH
. |  ||  | ||.|          |   . ||.|.|.. ||  .  |.   .  .  ..|||| . | ||.|| ..|.|.|. .   | | ||...|.|
GTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQEREACRFFQQIISGVEYCH

NELHIVHRDIKAENVLLDQNFNVRLIDFGLAGRISKIFPKLDFSCGSIGYMAPEIFSGHGYD-EQVDIWSTGVLLFALLTGYLPFSGQNSSDIKHNILHQ
. . ||||| | ||.|||.| |. . ||||    ..   .|  .|||  | |||. ||  |   .|||||.|| |.|.| |||||  .| ..   .|. .
R-HMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDG-EFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPFDDENTPTLYKKIKNG

NIEFPDYLSKDAKNLLSKMLERNPTKRISIQGIKQHSWF
  . |..||..||.|...||. .|.|||.|. |..|.||
EYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF

Kinase 97466.m00041.AA Ciliate-E2-Unclassified 13-266 25 1.1e-81 277.66 In-house 1-352 (352) Show / Hide
Range on Protein: 13-266
Range on HMM: 1-352/352
Sequence Identity: 25% (91 aa)

YTVLEIIDQSVHRTIYKARHNKTGAIVVIKVLPNSNNSHRRNV-Y--------DHAHEIQ-------------IMKMLDHPLTVDFYDAFSDDERTYIVM
|.....| |  . ..||..|.|.. . ..| .  ... ..... .        ..  ...             |.....||. | ....| |..  ||||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYLPRGSLFEYILQNGK-----------------LSEQISN-----NIFTQLISAIDYLHNELHIVHRDIKAENVLLDQN---FNVRLIDFGLAGRISK-
||.. |.|..|| ...|                 ..|| .      ..| |......||| ...|.||||| ||.|.|.|   .....||||.. .. . 
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

--------------IFPKLDFSCGSIGYM----APEIFSGHGYDEQ----VDIWSTGVLLFALLTGYLPFSGQNSSD----------------IKHNILH
              .. ...  ||...||    |||.. |..||..    .|||| ||.|...|.||.||...|. .                .. ||. 
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

QNIEFP--------DYLSKDAKNLLS----KMLERNPTKRISIQGIKQHSWF
.||.||        . .|. ||....    |||. || |||... |..| ||
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 97466.m00041.AA Pkinase 26-266 30 9.3e-78 269.43 Pfam 14-293 (293) Show / Hide
Range on Protein: 26-266
Range on HMM: 14-293/293
Sequence Identity: 30% (85 aa)

TIYKARHNKTGAIVVIKVLPNSNNSHRRNVYDHA-HEIQIMKMLDHPLTVDFYDAFSDDERTYIVMEYLPRG----SLFEYIL--QNGKL--SEQISNNI
. ||..| .|| ||..|... .....  ....    ||||||.|.||  | .||.| |. . |.||||.. |    .||.||   ..|..  ||.   ..
CVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFY

FTQLISAIDYLHNELHIVHRDIKAENVLLDQNFNV----RLIDFGLAGRI-SKIFPKLDFSCGSIGYMAPEIFS-GHGYDEQVDIWSTGVLLFALLTGYL
..|......|.|.   |.|||.| ||.|.|.| ..    ...|||||  .     . ..  ||...|||||.   | .|.  ||.|| |..|. .|.|..
MYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRP

PFSGQ------NSSDIKHNILHQNIEFPDYLS---------------------KDAKNLLSKMLERNPTKRISIQGIKQHSWF
||.|.      .   .  .|..  ..|. . .                     ...| .....|...|.||.... |.|| ||
PFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 97466.m00041.AA Ciliate-E2 13-266 24 3.6e-76 259.36 In-house 1-365 (365) Show / Hide
Range on Protein: 13-266
Range on HMM: 1-365/365
Sequence Identity: 24% (91 aa)

YTVLEIIDQSVHRTIYKARHNKTGA-----------------------IVVIKVLPNSNNSHRRNVYDHAHEIQ----------IMKMLDHPLTVDFYDA
| ....| |  . ..||... |..                        |. .|.. ...  .  .. .   ||.          |.. |.||  . .|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FS--DDERTYIVMEYLPRGSLFEYILQN-----------GKLSEQISNNIFTQLIS---------------AIDYLHNELHIVHRDIKAENVLLDQNFNV
|   ||.  |.||||.  |.||.|| .|           ....|.   .|..|...               |. |||.. .|.||||| ||.|.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

RLIDFGLAGRISKI----------FPKLDFS----------------------CGSIGYMAPEIFS---------GHGYDEQVDIWSTGVLLFALLTGYL
 .|||||. ....             ... .                      ||. |||||||..         ..|||...|||| ||.|. .|.|..
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFSGQNSSDIKHNILHQNIEFP------------------DYLSKDAKNLLSK----MLERNPTKRIS-IQGIKQHSWF
||          .|. ..|.||                  ...|...|.|..|    ||...| |||. .. |..| ||
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 97466.m00041.AA RSK 58-266 33 9e-72 244.76 In-house 46-278 (278) Show / Hide
Range on Protein: 58-266
Range on HMM: 46-278/278
Sequence Identity: 33% (79 aa)

HAH-EIQIMKMLD-HPLTVDFYDAFSDDERTYIVMEYLPRGSLFEYILQNGK---LSEQISNNIFTQLISAIDYLHNELHIVHRDIKAENVLLDQ---NF
|.  |..|...   ||  |. ..|| ... .|..|||.. | ||. ... .    .||     .. ....|...|| ...|.|||.| ||.|.|.   . 
HTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLH-QQGIIHRDLKPENILYDDESNEG

NVRLIDFGLA--GRISKIFPKLDFSCGSIGYMAPEIFS----GHGYDEQVDIWSTGVLLFALLTGYLPFSG---QNSSDIKHNILHQN--IEFP--DYLS
 ..|.|||..  .|... ..   | |..| |||||.      . |.|...|.|| |||.. .|||..|| |   .|...|  .|.. .   ..|  .|||
HIKLTDFGFCKQFRCDHNQWTMTF-CYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLS

KDAKNLLSKMLERNPTKRIS-----IQGIKQHSWF
..||.|..|||.|.| ||..     .. ||||.||
QEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase 97466.m00041.AA CAMK-Unique 13-266 23 2.2e-70 231.5 In-house 1-363 (363) Show / Hide
Range on Protein: 13-266
Range on HMM: 1-363/363
Sequence Identity: 23% (86 aa)

YTVLEIIDQSVHRTIYKARHNKTGAIVVIKVLPNSNNSHRRNVY-----------------DHAHEIQIMKMLDHPLTVDFYDA----FSDDE-------
|. ..|| .     .|..   .|| . ..|.. .   .  ...                      |.||.||.|||  . .||     | |..       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------RTYIVMEYLPRGSLFEYILQ--------------------NGKLSE--QISNNIFTQLISAIDYLHNELHIVHRDIKAENVLLDQNFN----
        . ||||||.. | ||..|..                    .|..||    . .|...| ||. |.|. . |||||.|.||...  .|.    
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHS-QDIVHRDLKLENIMVCYSFKDNNH

------------VRLIDFGLAGRIS-KIFPK-LDFSCGSIGYMAP--------------EIFSGHGYDEQV----DIWSTGVLLFALLTGYLPFSGQNSS
            . |.||||.  .. .. .  .   ||.. ||||              |.  ...||.|.    |||| ||... .|.|..|| .... 
HRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECED

--------DIKHNILHQNI-EF-------PDYLSKDAKNLLSKMLERNPTKRISIQGIKQHSWF
         |  .|.  .. .|       ||| |. ||... . ... | .|.|.  ...|.|.
RDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI

Kinase 97466.m00041.AA ULK 26-266 26 3.2e-68 232.97 In-house 14-329 (329) Show / Hide
Range on Protein: 26-266
Range on HMM: 14-329/329
Sequence Identity: 26% (85 aa)

TIYKARHNKT----GAIVVIKVLPNSNNSHRRNVYD-------HAHEIQIMKMLD--------HPLTVDFYDAFSDDER--TYIVMEYLPRGSLFEYILQ
. ||.|..||    . .|..|... .  .   | ..          ||.|||.|.        || .| .|| | ..    .||.||| . | |..|| .
KVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKK

NGK----------LSEQISNNIFTQLISAIDYLHNELHIVHRDIKAENVLLDQNFN------------VRLIDFGLAGRISK----IFPKLDFS-----C
|.|          ||||.  ..| |....  .|| .  |.||||| .|.|.. ..             . . |||.|  ...    ..  . ..     |
NKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELH-KHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLC

GSIGYMAPEIFSGHG----YDEQ-VDIWSTGVLLFALLTGYLPFSGQNSSDIKHNILHQN---------------IEFPDY-----LSKDAKNLLSKMLE
|.  ||||.|..|.|    |..  .|||| |.... .|.|. ||...  .| ...|. ..               ..||..     .|.. |.|...||.
GTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQ

RNPTKRISIQGIKQHSWF
.....|||.. . .| ||
YDEKDRISWEELFNHPWF

Kinase 97466.m00041.AA TyrKc 13-266 21 7.7e-15 17.25 SMART 1-280 (280) Show / Hide
Range on Protein: 13-266
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

YTVLEIIDQ----SVHRTIYKARHNKTGAIVVIKVLPNSNNSHRRNVYDHAHEIQIMKML--DHPLTVDFYDAFSDD-------ERTYIVMEYLPRGSLF
 | ....       |.. ..|         | .|.| ..       . |  .|..||..|  .||  | .| . ...       |  .||||| | |.| 
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK

EYILQNGK-LSEQISNNIFTQLISAIDYLHNELHIVHRDIKAENVLLDQNFNVRLIDFGLAGRISKI-----FPKLDFS----CGS----IGYMAPEIFS
.|.  ... |. .   .. .|  .  .|||   ...|||. | |.|.. |. |.  ||||.  |          .   .    .|     |  |||| . 
DYLRKHRPKLCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

GHGYDEQVDIWSTGVLLFALLT-GYLPFSG-----QNSSDIKHNILHQ-NIEFPDY--------LSKDAKNLLSKMLERNPTKRISIQGIKQHSWF
 . . .. |.|| ||... ..| |  | .|      . ... ... .    . |..         ...  .. ..  ...| .| . . |  |. |
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase 97466.m00041.AA Pkinase_Tyr 26-159 29 5.2e-11 37.91 Pfam 14-158 (270) Show / Hide
Range on Protein: 26-159
Range on HMM: 14-158/270
Sequence Identity: 29% (44 aa)

TIYKARHN----KTGAIVVIKVLPNSNNSHRRN--VYDHAHEIQIMKML-DHPLTVDFYDAFS-DDER--TYIVMEYLPRGSLFEYILQ----NGKLSEQ
..||.. .    .|.  | .|.|..  ... ..    |  .|..||| | .||  | .| . . ..|    |||||| | |.| .|  .    ...|. .
EVYKGTWKGDPDNTKIPVAVKMLKE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMK

ISNNIFTQLISAIDYLHNELHIVHRDIKAENVLLDQNFNVRLIDFGLA
   .. .|  .. .||. . ...|||. | |.|.. |. |.  |||||
DLLQMCWQIAKGMEYLE-SKNCIHRDLAARNCLVTENNVVKICDFGLA

Kinase 97466.m00041.AA Pkinase_Tyr 179-224 31 0.012578 9.52 Pfam 181-228 (270) Show / Hide
Range on Protein: 179-224
Range on HMM: 181-228/270
Sequence Identity: 31% (15 aa)

MAPEIFSGHGYDEQVDIWSTGVLLFALLT-GYLP-FSGQNSSDIKHNI
|||| ..   . .. |.|| |||.. ..| |  | . |   ..... |
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYI