90524.m00025

Species: T.vaginalis
Alias: 90524.m00025, TvagK0664
External Links:
Annotation:

Classification

Group: CMGC
Family: DYRK
Subfamily: YAK

Sequence

Name Sequence Type Origin Length Description Download
90524.m00025.AA Protein None 378 None Fasta, JSON
90524.m00025.kin_dom Protein Kinase Domain None 327 None Fasta, JSON

Protein domain

Protein domains of 90524.m00025.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 90524.m00025.AA DYRK 48-374 30 8e-68 231.64 In-house 1-320 (320) Show / Hide
Range on Protein: 48-374
Range on HMM: 1-320/320
Sequence Identity: 30% (103 aa)

YTVVGKLGEGRWGQVYEVSLPNPSGGDPLLYAMKISKSTRDSLEQFQYETQALAYIKANSSDEDLQYVSDVHAYFQYQGHICIVLDKCGPSTLSFLQAIE
|.... .| |  |||  .       .   . |.|| ..  . . | | |.. | |.. .  ..|  ..     ||....| ||| .    .   ||    
YEILEYIGKGSFGQVVKCW----DHKTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQ-DPDDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNH

YSGL-PLNLVQSVLRDVLTALKNLANL-SIIHCDVKPENICALND--TSSHVKLVDFGSCVVVNTIQNTYTQSRYYRAPEVALHLEYDTKADVWSTGCVA
  |. .||||..... .||.|| |... .||||| |||||  |..    | .|..||||   ..    || |||.|||||| | . |... |.|| ||. 
FQGFFSLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIM-LKQPRNKSTIKVIDFGSSCFEHQRIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCIL

AELMLGLPLFPAESERHLICLIAQMLGPYPANMREQT--ERHDELFMPDETLKSAEILCLENDENFVNYQPYFIHEHLDDIIMNYAYPDDMTDEQISVEM
||| .| |||| |.| ... .| ..||..| .| ..   .| .. |            | |...  .... |.. .   . . .. .| ....     . 
AELFTGWPLFPGENEYDQLACIMEVLGMPPKWMIDKGRCRRKHKFFDC-----FMYCECDEWTKQNKITDHYMTPKCHPTKR-GQRRPPGRRNWDPRHQ-

EHRRVFIDLLQQMLQIDPALRITADVALQHPFL
 ... |.|.....||.||. |||.  |||||..
CDDHQFKDFIKKCLQWDPHKRITPSQALQHPWF

Kinase 90524.m00025.AA CMGC 48-374 17 1.3e-54 177.4 In-house 1-513 (513) Show / Hide
Range on Protein: 48-374
Range on HMM: 1-513/513
Sequence Identity: 17% (94 aa)

YTVVGKLGEGRWGQVYEVSLPNPS----------GGDPLLYAMKISKSTRDSLEQFQ-------------YETQALAYIKA----------NSSDEDLQY
|....|.|||  |.||.    .              .  ..|.|. |.     || .              | . | ...           ......  .
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

VSDVHAYFQYQG-----------------HICIVLDKCGPSTLSFLQAIE--YSG---LPL-------------NLVQSVL------RDVLTALK--NLA
.   . .|.. .                 |...| . .. . . ...     | |   .||             ..... .      . .|..||   . 
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

NLS--IIHCDVKPENICALNDTSS------------------HVKLVDFGSCVVVNT------------------------IQNTYTQSRYYRAPEVALH
     |||.| |||||   ... .                  ..|. |||..  ...                           .| ..|.|||||. | 
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

LE----------YDTKADVWSTGCVAAELMLG--------LPLFPAESE-----------RHLICLIAQMLGPYPANMREQTERH------DE-----LF
 .          |.|. |.|| ||. ||...|         |||| .||            . . .| ..||. . .| ....||      .|     . 
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGKRHFNFCKHEEEWPNMIK

MPDETL--------------KSAEILCLENDENFVNYQP------YFIHEHLDDIIMNYAYPDDMTDEQISVEME-------------------HRRVFI
.|.  .              ..   . ...  .| ...|      .  |  .|| . |.         ...   .                       .|
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDD-N-NKK--------AMVF-NWIYEEKFKSHKFNHQFKRKCCDPQAI

DLLQQMLQIDPALRITADVALQHPFL
|||..|||.||. ||||. |||||..
DLLKKMLQYDPDKRITAEQALQHPYF

Kinase 90524.m00025.AA S_TKc 48-374 20 1.8e-53 184.88 SMART 1-231 (231) Show / Hide
Range on Protein: 48-374
Range on HMM: 1-231/231
Sequence Identity: 20% (69 aa)

YTVVGKLGEGRWGQVYEVSLPNPSGGDPLLYAMKISKSTRDSLEQFQYETQALAYIKANSSDEDLQYVSDVHAYFQYQGHICIVLDKCGP---STLSFLQ
|... |.|.|  |.|| .   .    .  ..|.|| |      |... | | |          .  ..   . .||  .|...|.. |.    . .....
YEILRKIGKGAFGKVYKCRHKK----TGRIVAIKIIK------EHIRREIQILKK--------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIK

AIEY----SGLPLNLVQSVLRDVLTALKNLANLSIIHCDVKPENICALNDTSSHVKLVDFGSCVVVNTIQNTYTQSRYYRAPEVALHLEYDT-KADVWST
   .    ...|   ...... .. ||. . .. |||.|.|||||  |..   |.|. |||.. ..    .|.  ...|.||||     |.. |.|.|| 
KRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENI-LLDE---HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSC

GCVAAELMLGLPLFPAESERHLICLIAQMLGPYPANMREQTERHDELFMPDETLKSAEILCLENDENFVNYQPYFIHEHLDDIIMNYAYPDDMTDEQISV
||. .|.. | |.||     ..  .. ...                                                                      
GCILYEMLCGYPPFP-----QMQMMFKKIG----------------------------------------------------------------------

EMEHRRVFIDLLQQMLQIDPALRITADVALQ-------HPFL
     . ..|.....|| ||. |.||  |||       ||..
----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 90524.m00025.AA HIPK 48-374 32 1.9e-51 160.03 In-house 1-329 (329) Show / Hide
Range on Protein: 48-374
Range on HMM: 1-329/329
Sequence Identity: 32% (109 aa)

YTVVGKLGEGRWGQVYEVSLPNPSGGDPLLYAMKISKSTRDSLEQFQYETQALAYIKANSSDEDLQYVSDVHAYFQYQGHICIVLDKCGPSTLSFLQAIE
| |.  || |  |||  |     . ..  . |.|| |       | | | . |. ..  ..||    .     .|. . |.|.| .        |.   .
YEVLEFLGRGTFGQV--VKCWKRGTNE--MVAIKILKNHPYYARQGQIEVSILHCLSQENADE--YHFVRAYECFHHKNHTCLVFEMLEQNLYDFQKQNK

YSGLPLNLVQSVLRDVLTALKNLANLSIIHCDVKPENICALNDTSS--HVKLVDFGSC-VVVNTIQNTYTQSRYYRAPEVALHLEYDTKADVWSTGCVAA
.. |||. .  .|  |||||. | .|..|| | |||||     |     || .||||   | ....||| |||||||||. | | .  . |.|| ||| |
FMPLPLKHIRPILQQVLTALMKLKELGLIHADLKPENIMLVDPTRCPYRVKVIDFGSASHVSKVVCNTYLQSRYYRAPEIILGLPFCENHDMWSLGCVIA

ELMLGLPLFPAESERHLICLIAQMLGPYPANMREQTERHDELF-------MPDETLKSAEILCLENDENFVNYQPYFIHEHLDDIIMNYAYPDDMTDEQI
||.|| ||.|  .|  .|  | |  .     . ..  .   .|        .   ||  |    .      . . | |  .|||.  .  .  |   .. 
ELFLGWPLYPGADEYDQIRYICQTQHLPHEHLLHAACKKHRFFDRDKQSKFRPWRLKHIEEHEQQTSVKSKEARKY-IFNCLDDMPEV-NMLVDPERQDY

SVEMEHRRVFIDLLQQMLQIDPALRITADVALQHPFL
 ||   || |...| .|. .|.  |||   ||.||| 
RVEKIDRREFVHVLKKMCTWDAHKRITPCEALNHPFV

Kinase 90524.m00025.AA DYRK1 48-374 30 2.1e-48 167.14 In-house 1-321 (321) Show / Hide
Range on Protein: 48-374
Range on HMM: 1-321/321
Sequence Identity: 30% (101 aa)

YTVVGKLGEGRWGQVYEVSLPNPSGGDPLLYAMKISKSTRDSLEQFQYETQALAYIKANSSDEDLQY-VSDVHAYFQYQGHICIVLDKCGPSTLSFLQAI
| .   .| | .|||           .  . |.|| |  .  ..| | | . |  .  |  |.. .| .  .   | .  |.|.|..         |.  
YEIDSLIGKGSFGQVVKAYDHQ----EQEYVAIKIIKNKKPFYNQAQIEIRLLELM--NKHDKEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNT

EYSGLPLNLVQSVLRDVLTALKNLA--NLSIIHCDVKPENICALNDTSSHVKLVDFGSCVVVNTIQNTYTQSRYYRAPEVALHLEYDTKADVWSTGCVAA
.. |  |||..   . ..|||  ..   |.|||||.|||||   |   | .|..||||   ..     | |||.||.||| | .|||.. |.|| ||.  
HFRGVSLNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENILLCNPKRSAIKIIDFGSSCQLGQRIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILV

ELMLGLPLFPAESERHLICLIAQMLGPYPANMREQTERHDELFMPDETLKSAEILCLENDENFVNYQPYFIHEHLDDII-MNYAYPDDMTDEQISVEMEH
|.  | |||   .|   .  |  .||  |..| .|. .    |   | ..     |. . .   .|.  . . .|..|. ..   |.    .     .| 
EMHTGEPLFSGSNEVDQMNKIVEVLGMPPKHMIDQAPKAHKYF---EKDPDNTWYCKKTRDKKKHYKE-PCTRKLHEILGVETGGPGGRRKGEPGHSVED

RRVFIDLLQQMLQIDPALRITADVALQHPFL
   | ||...||| ||. |||   ||||.|.
YLKFKDLIKRMLQYDPKQRITPYYALQHSFF

Kinase 90524.m00025.AA DYRK2 90-258 36 1.2e-42 136.36 In-house 39-207 (318) Show / Hide
Range on Protein: 90-258
Range on HMM: 39-207/318
Sequence Identity: 36% (62 aa)

LEQFQYETQALAYIKANSSDEDLQYVSDVHAYFQYQGHICIVLDKCGPSTLSFLQAIEYSGLPLNLVQSVLRDVLTALKNLANLSIIHCDVKPENICALN
..| . |.. | .|. .  |.    |     || . .|.||...  . .  ...   .. |. |.||    . .|..|. |    ||||| |||||    
HNQAYEEIRILHHIRRQDKDNTMNCVH-MLDYFYFRNHHCITFELLSMNLYEYIKKNHFQGFSLQLVRRFAHSILQCLRFLHKNNIIHCDLKPENILLKQ

DTSSHVKLVDFGSCVVVNT-IQNTYTQSRYYRAPEVALHLEYDTKADVWSTGCVAAELMLGLPLFPAESE
 . | .|..||||   ..     || |||.|||||| | . |..  | || ||..|||  | |||| | |
WNRSGIKVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYTGYPLFPGENE

Kinase 90524.m00025.AA Pkinase 48-265 23 2.4e-33 119.02 Pfam 1-230 (293) Show / Hide
Range on Protein: 48-265
Range on HMM: 1-230/293
Sequence Identity: 23% (59 aa)

YTVVGKLGEGRWGQVYEVSLPNPSGGDPLLYAMKISKSTRDSLEQFQY-----ETQALAYIKANSSDEDLQYVSDVHAYFQYQGHICIVLDKCGP-----
|....|.|.|  |.||.    . .     ..|.|| |  ... .. |.     | | .. ..         ..   . .|.. .||..|.. |.      
YHIGRKIGSGSFGCVYKCHHKGTGK----IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-------HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVM

STLSFLQ---AIEYSGLPLNLVQSVLRDVLTALKNLANLSIIHCDVKPENICALNDTSSHV----KLVDFGSC----VVVNTIQNTYTQSRYYRAPEVAL
.  ....      .. .. . ...... .| .|. . . .|||.|.|||||  | |   |.    |. |||..       |.  .|.. ...|.|||| .
DLFDYISTWRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENI--LIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR

-HLEYDTKADVWSTGCVAAELMLGLPLFPAE------SERHLICLI
 . .|..|.|.|| ||. .|...| |.|| .      .....||.|
GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRI

Kinase 90524.m00025.AA YAK 150-279 41 3.7e-32 106.27 In-house 102-231 (347) Show / Hide
Range on Protein: 150-279
Range on HMM: 102-231/347
Sequence Identity: 41% (54 aa)

GLPLNLVQSVLRDVLTALKNLANLSIIHCDVKPENICALNDTSSHVKLVDFGSCVVVNTIQNTYTQSRYYRAPEVALHLEYDTKADVWSTGCVAAELMLG
|.  .|..  .  .| ..  |.|  ||||| |||||   .  .  .|..||||         || |.|.||.||. .   | |  | || ||. ||| ||
GFSFQLIRQWTKQILDGMCVLENKQIIHCDLKPENIMLCKPNKPEIKIIDFGSSCQEKKMVYTYIQQRHYRSPEIIVWMIYCTSIDMWSLGCIVAELFLG

LPLFPAESERHLICLIAQMLGPYPANMREQ
||.||  ||   |  |  |||  |  | .|
LPIFPGNSEYNQIKRIIDMLGYPPSWMIDQ

Kinase 90524.m00025.AA Ciliate-E2-Unclassified 48-374 18 6.6e-30 100.94 In-house 1-352 (352) Show / Hide
Range on Protein: 48-374
Range on HMM: 1-352/352
Sequence Identity: 18% (73 aa)

YTVVGKLGEGRWGQVYEVSLPNPSGGDPLLYAMKISK--------STRDSLEQFQYETQALAYIKANSSDE-------------DLQYVSDVHAYFQYQG
|... ..|.|  |.||..     .  . ..||||. |        . . .  ..  | ...  .|  ....             .  ..   . .|| . 
YKIIKQIGQGGFGKVYKCQH---KKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQ

HICIVLDKCGPSTLSFLQAI---------------EYSG-LPLNLVQ-----SVLRDVLTALKNLANLS-IIHCDVKPENICALNDTSS--HVKLVDFGS
.|.||...|   .|..   .               ...  .. . ..       .. .| .|. |     ||| | |||||  ...  .  ..|. |||.
NIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENIL-FDNNGKNYYIKIIDFGI

C------------------VVVNTIQNTYTQSRYYR----APEVALHLEYD----TKADVWSTGCVAAELMLGLPLFPAESERHLICLIAQMLGPYPANM
.                  .  . ...| ... .|     ||||    .||     |.|.|| |... |.. | . |.....    .||.| .     | 
SKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWI-N---N-

REQTERHDELFMPDETLKSAEILCLENDENFVNYQP----YFIHEHLDDIIMNYAYPDDMTDEQISVEMEHRRVFIDLLQQMLQIDPALRITADVALQHP
          .    . |  .  ..... .| .. .    . ....  |.|                         ||||.||. .|  |||.. .|.||
----------A----YRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFIN------------------------DLLQKMLKKNPNKRITFEQILNHP

FL
..
WF

Kinase 90524.m00025.AA DyrkP 156-276 39 7.9e-28 88.19 In-house 108-228 (323) Show / Hide
Range on Protein: 156-276
Range on HMM: 108-228/323
Sequence Identity: 39% (48 aa)

VQSVLRDVLTALKNLANLSIIHCDVKPENICALNDTSSHVKLVDFGSCVVVNTIQNTYTQSRYYRAPEVALHLEYDTKADVWSTGCVAAELMLGLPLFPA
.| .   .| ||  .  | .||||.|||||        .||..||||   .      | ||| |||||| .   || . |.|| ||. |||  |  ||  
LQKITQQILIALDYIHSLRLIHCDLKPENILMKSYPKCQVKIIDFGSSCFIHDHLSSYVQSRSYRAPEVIIGCKYDYRIDMWSLGCILAELWTGNVLFQN

ESERHLICLIAQMLGPYPANM
.    |.  .  ..||.|  |
DNIQGLLARVIGIIGPFPEWM

Kinase 90524.m00025.AA CLK 48-186 26 1.1e-25 73.4 In-house 1-146 (350) Show / Hide
Range on Protein: 48-186
Range on HMM: 1-146/350
Sequence Identity: 26% (39 aa)

YTVVGKLGEGRWGQVYEVSLPNPSGGDPLLYAMKISKSTRDSLEQFQYETQ-ALAYIKAN-SSDEDLQ-YVSDVHAYFQY-QGHICIVLDKCGPSTLSFL
|..| .||||  | |.|.   . .  .. ..| || ..     |. . |..  .  |... ... . .  .    ..| |  |||||| .. | |. .|.
YEIVCTLGEGTFGKVVEC---WDHKNGKKYVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFDYGHGHICIVFELYGLSIYDFM

QAIE------YSGLPLNLVQSVLRDVLTALKNLANLSIIHCDVKPENIC
 .        | ..|.. ...  .  ..|.| |  ....| | ||||||
KSNNSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHDMKLTHTDLKPENIC

Kinase 90524.m00025.AA PRP4 150-276 37 6.7e-21 73.28 In-house 102-228 (320) Show / Hide
Range on Protein: 150-276
Range on HMM: 102-228/320
Sequence Identity: 37% (48 aa)

GLPLNLVQSVLRDVLTALKNLANLSIIHCDVKPENICALNDTSSHVKLVDFGSCVVVNTIQNT-YTQSRYYRAPEVALHLEYDTKADVWSTGCVAAELML
|| |. | |  .  . ||| | .. |.| |.|| ||   |   .  |..||||   ..    | | .||.|||||. .  .||   |.||.||  .||  
GLHLKAVRSYAQQLFLALKHLKKCNILHADIKPDNIL-VNESKNTLKMCDFGSASHIHENEITPYLVSRFYRAPEIIIGHPYDYQIDMWSVGCTLYELYT

GLPLFPAESERHLICLIAQMLGPYPANM
|  .||  .  | . |.  . | .|  |
GKIMFPGKTNNHMLKLFMDYKGKMPNKM

Kinase 90524.m00025.AA YAK 313-374 33 6.6e-16 50.15 In-house 286-347 (347) Show / Hide
Range on Protein: 313-374
Range on HMM: 286-347/347
Sequence Identity: 33% (21 aa)

YFIHEHLDDIIMNYAYPDDMTDEQISVEMEHRRVFIDLLQQMLQIDPALRITADVALQHPFL
||    | ||. .. .   |  . .  .  || .|||.. |.|| .|  | ..  | ||||.
YFQYKCLNDIKNYMYFKQFMRNQDDTKNNRHRDCFIDFINQLLQLNPRERWKPMQAMQHPFI

Kinase 90524.m00025.AA CLK 192-276 34 3.7e-15 41.21 In-house 183-271 (350) Show / Hide
Range on Protein: 192-276
Range on HMM: 183-271/350
Sequence Identity: 34% (31 aa)

SSHVKLVDFGSCV---VVNTIQNTYTQSRYYRAPEVALHLEYDTKADVWSTGCVAAELMLGLPLFPAESERHLICLIAQMLG-PYPANM
. |....||||       ..   |  ..| |||||| | | . .. |||| ||.  || .|  ||.  ..|    ..   .| | |  |
NTHICVIDFGSATKIRFDHEHHSTIVSTRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLFQTHDNREHLAMMERIMGMPIPQWM

Kinase 90524.m00025.AA CLK 342-374 54 1.2e-11 30.49 In-house 319-350 (350) Show / Hide
Range on Protein: 342-374
Range on HMM: 319-350/350
Sequence Identity: 54% (18 aa)

EHRRVFIDLLQQMLQIDPALRITADVALQHPFL
|||. ..||...|| .||. |||.. |||||| 
EHRQ-LFDLIRKMLEYDPSKRITCKDALQHPFF

Kinase 90524.m00025.AA PRP4 349-374 53 2.1e-09 30.64 In-house 295-320 (320) Show / Hide
Range on Protein: 349-374
Range on HMM: 295-320/320
Sequence Identity: 53% (14 aa)

DLLQQMLQIDPALRITADVALQHPFL
||| ..|. ||. |||   ||.|||.
DLLDKCLMLDPKKRITCNEALKHPFI

Kinase 90524.m00025.AA DyrkP 346-374 55 3.1e-08 22.49 In-house 295-323 (323) Show / Hide
Range on Protein: 346-374
Range on HMM: 295-323/323
Sequence Identity: 55% (16 aa)

VFIDLLQQMLQIDPALRITADVALQHPFL
.|||  .|.||||   | ||  |||||..
MFIDFVRQCLQIDFTRRPTAKEALQHPWF

Kinase 90524.m00025.AA DYRK2 347-374 39 9.3e-08 20.95 In-house 291-318 (318) Show / Hide
Range on Protein: 347-374
Range on HMM: 291-318/318
Sequence Identity: 39% (11 aa)

FIDLLQQMLQIDPALRITADVALQHPFL
||| ... .. ||. |.|.. ||.||..
FIDFIKRCFEWDPSERMTPSQALKHPWI

Kinase 90524.m00025.AA Pkinase 347-374 39 1.1e-07 28.23 Pfam 266-293 (293) Show / Hide
Range on Protein: 347-374
Range on HMM: 266-293/293
Sequence Identity: 39% (11 aa)

FIDLLQQMLQIDPALRITADVALQHPFL
..|..  .|. ||. |.||. .||||..
CKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 90524.m00025.AA TyrKc 48-286 17 3e-06 -120.9 SMART 1-280 (280) Show / Hide
Range on Protein: 48-286
Range on HMM: 1-280/280
Sequence Identity: 17% (53 aa)

YTVVGKLGEGRWGQVYEVSLPNPSGGDPLLYAMKISKSTRDSLEQFQYETQALAYI--KANSSDEDLQYVSDVHAY---FQYQGHICIVLDKCGP-STLS
 |   |||||  |.||.  .        .  | |  |.    .| |  | . .  .  .       .. .  .      | | . ..||.  .   . ..
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNI---VRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

FLQAIEYSGLPLNLVQSVLRDVLTALKNLANLSIIHCDVKPENICALNDTSSHVKLVDFGSCVVVNTI------QNTYT-----QSR-----YYRAPEVA
.|.. .   |..    |   ..      |.   .|| |    |.   ..   .||  ||| .  .         . .|.     ...        |||. 
YLRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

LHLEYDTKADVWSTGCVAAELM-LGLPLFPA-----ESERHLICLIAQM----LGPY---------PANMREQTER---------------HDEL
 . .. || |||| | .  |.. .| .  |       | ...| .. |       |.         |. | .  ..               |...
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase 90524.m00025.AA DYRK2 48-65 33 0.069189 1.54 In-house 1-18 (318) Show / Hide
Range on Protein: 48-65
Range on HMM: 1-18/318
Sequence Identity: 33% (6 aa)

YTVVGKLGEGRWGQVYEV
|...  .| |  ||| ..
YEILEVIGKGSFGQVVKC