Gene 89154.m00270 (T.vaginalis)

89154.m00270

Species: T.vaginalis
Alias: 89154.m00270, TvagK0544
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag2

Sequence

Name Sequence Type Origin Length Description Download
89154.m00270.AA Protein None 326 None Fasta, JSON
89154.m00270.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of 89154.m00270.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 89154.m00270.AA CAMKL 22-270 29 7.3e-74 235.06 In-house 1-293 (297) Show / Hide 
Range on Protein: 22-270
Range on HMM: 1-293/297
Sequence Identity: 29% (86 aa)

YTYIDTIGKGATSIVIKAMN-NKTGKMVACKVVSRLVLMKLSQLEMF------------EQELRILEKVK---HKNICKLYEILYYEEV------IMVVI
|. ..|.|||. . |  |..   ||..|| |.. .  . .  . ..             ..| .|.....   |.||.||||... .|       |  | 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

KYCSNGD--LFDYITSL----GTVGEVQCYRIILQLAKALSYLHSRKICHRDIKPENIVFDENM--IPKLIDFGISTEVLN-----NARKNHCSGTFLYC
 |||.|.  ||||| .     |   | .. |.  |.  |..|.||..|.||||||||| .|||.    |.|||| |..  .     .   . . |.  |.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

PPECFNS--VQFDPMAADIWSLGMTLYTMLFGCFPWKEQ--------SEDEIVNFIST-TQITVPPTCSQRMRMILRRMLEFDPNLRPSADDLVN
.|| |..   ..|  ..||||.| .||.|..| .|....           .  . | . .......  | . | ..|.||. .|. ||......|
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCGYYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMN
Kinase 89154.m00270.AA CAMK 27-270 19 8.6e-73 233.67 In-house 1-421 (425) Show / Hide 
Range on Protein: 27-270
Range on HMM: 1-421/425
Sequence Identity: 19% (84 aa)

TIGKGATSIVIKAMNNKTG------------KMVACKVVSR--LVL-----------------------MKLSQLEMFEQELRILEK-------VKHKNI
|.|.|. ..| .... .|.            . ||.|....  |                         .. . ......|..|. |       ..|.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

CKLYEILYYEEV-------------------IMVVI---KYCSNG----DLFDYITSL---------------GTVGEVQCYRIILQLAKALSYLHSRKI
.||||.   ...                   .  |     |||.|    ||||||..                | . | .. |.. |.. |. |.||..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

CHRDIKPENIVFDENM-----------------IPKLIDFGISTEVLN------------------------NARKNHCSGTFLYCP-PECFNS------
.|||.||||| .|.|.                   |.|||| ....                          .   . . ||  |.. || .|.      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------VQFDPMAADIWSLGMTLYTMLFGCFPWKEQSEDEIVN-------------FISTTQIT-VPPT-----------------------CSQRMRM
        . .. ..|.||.|  ||.|| |..|. . ...||..              | . . .  ||                        .||  . 
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

ILRRMLEFDPNLRPSADDLVN
 .|.||. ||. |.....  |
LIRKMLQVDPEKRMTIEQCLN
S_TKc 89154.m00270.AA S_TKc 22-272 30 5.7e-72 246.34 SMART 1-231 (231) Show / Hide 
Range on Protein: 22-272
Range on HMM: 1-231/231
Sequence Identity: 30% (82 aa)

YTYIDTIGKGATSIVIKAMNNKTGKMVACKVVSRLVLMKLSQLEMFEQELRILEKVKHKNICKLYEILYYEEVIMVVIKYCSN--GDLFDYITSLGT---
|. ...||||| . | |. ..|||. ||.|...          |....|..||.| .|.||.|||.. .  . . .|  ||..  ||||||| . |.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---VGEVQCYRIILQLAKALSYLHSRKICHRDIKPENIVFDENMIPKLIDFGISTEVLNNARKNHCSGTFLYCPPECFNSVQFDPMAADIWSLGMTLYTM
     | .. ... |...|| |.||..|.|||.||||| .||    |..|||.....      ... ||  |..|| .   .... ..|.||.| .|| |
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LFGCFPWKEQSEDEIVNFISTTQITVPPTCSQRMRMILRRMLEFDPNLRPSADDLVN---------LI
| |. |.    .... . |           |. .. ..|..|..||. ||.| .. .          .
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase 89154.m00270.AA Pkinase 22-272 26 3.2e-71 247.72 Pfam 1-293 (293) Show / Hide 
Range on Protein: 22-272
Range on HMM: 1-293/293
Sequence Identity: 26% (79 aa)

YTYIDTIGKGATSIVIKAMNNKTGKMVACKVVSRLVLMKLSQLEMFEQ--ELRILEKVKHKNICKLYEILYYEEVIMVVIKYCSNG----DLFDYIT--S
|. . .||.|. . | |... .|||.||.|....    | ....      |..|. ...|.||..||.. ...  | .|  || .|    ||||||.  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

LGTV--GEVQCYRIILQLAKALSYLHSRKICHRDIKPENIVFDENMIP----KLIDFGISTE--VLNNARKNHCSGTFLYCPPECFNSVQFDPMAADIWS
 |..   | .| ....|....| |.||..|.|||.||||| .|.|. .    |..|||..      ||   ..  ||  |..||  .. | .. ..|.||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGMTLYTMLFGCFPWKEQ------SEDEIVNFISTTQITVPPTCS---------------------QRMRMILRRMLEFDPNLRPSADDLVNL--I
.| .|| ||.| .|....      ....... |  ...  .   .                     . .. .....|..||. ||.|.....   .
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 89154.m00270.AA MARK 22-270 34 2.8e-65 212.37 In-house 1-258 (262) Show / Hide 
Range on Protein: 22-270
Range on HMM: 1-258/262
Sequence Identity: 34% (88 aa)

YTYIDTIGKGATSIVIKAMNNKTGKMVACKVVSRLVLMKLSQLEMFEQELRILEKVKHKNICKLYEILY--YEEV-IMVVIKYCSNGDLFDYITSL--GT
|  . |||.|. . | .| . .||. || |.. .  | .  ...... |..|. |..|.|| ||...     |.  | ..  |.|.|.|.||| .   | 
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

VGEVQCYRIILQLAKALSYLHSRKICHRDIKPENIVFDENM--IPKLIDFGISTEVLNNARKNHCSGTFLYCPPECFNSVQFDPMAADIWSLGMTLYTML
  |  ..||  |.  |..|.||. |.|||||||||  |||.    |.|||| |... .. . | . ||  |..|| |..   |  ..||||||  ||.|.
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

FGCFPWKEQS--EDEIVNFISTTQITVPPTCSQRMRMILRRMLEFDPNLRPSADDLVN
 |.||.....  . |.   | . . ..|.  |   | ...|.| ..|. ||.......
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMK
Kinase 89154.m00270.AA Ciliate-E2 22-270 23 2e-59 202.64 In-house 1-361 (365) Show / Hide 
Range on Protein: 22-270
Range on HMM: 1-361/365
Sequence Identity: 23% (89 aa)

YTYIDTIGKGATSIVIKAMNNKTGKMVA--------------------CKVVSRLVLMKLSQLEMFEQELR-------------ILEKVKHKNICKLYEI
|  |  ||.|. ..| |. . |..|..|                     . . ..   .. |... ....|             |||...|.||.|.|| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

LY--YEEVIMVVIKYCSNGDLFDYITSLGTVG-----------EVQCYRIILQLAK---------------ALSYLHSRK-ICHRDIKPENIVFDENMIP
 .   .. |  |  ||. ||||||| .  .             | .. .|. |...               || ||||.. |.|||||||||.|     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLIDFGISTEVLNNARKNH--------------------------------CSGTFLYCPPECFNSVQFDP--------MAADIWSLGMTLYTMLFGCFP
|.||||.|... ..  ..                                 . ||  | .|| .|. . |          ..||||||..|| |||| .|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

WKEQSEDEIVNFISTTQITVPPT------------------CSQRMRMILRR----MLEFDPNLRPS-ADDLVN
.         . |   .|  |.                   .|| .  ....    ||. ||. |.. .... |
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN
Kinase 89154.m00270.AA ULK 22-260 25 3.7e-58 199.54 In-house 1-310 (324) Show / Hide 
Range on Protein: 22-260
Range on HMM: 1-310/324
Sequence Identity: 25% (81 aa)

YTYIDTIGKGATS-IVIKAMNNKT---GKMVACKVVSRLVLMKLSQL-------EMFEQELRILEKVK---HKN--ICKLYEILYYEEV--IMVVIKYCS
|  .. .|||.    | |. |.||   .. ||||....  . | ...       .....| .|. | |   |.|  |.|||....      |  .  || 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGDLFDYITSLGTVGEVQ----------CYRIILQLAKALSYLHSRKICHRDIKPENIVFDEN------------MIPKLIDFGISTEVLNN-ARKNHCS
 |||..||   .. .| .          .  .. |.. .. .||...| ||||||.||   ..             . |. ||| .  | ||   .. | 
GGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

---------GTFLYCPPECFN----SVQFDPMAADIWSLGMTLYTMLFGCFP---WKEQSED----EIVN-------FISTTQITVP-----PTCSQRMR
         || ||  |. ..      ...   .||||||. .| ||.|  |   |  ....    . .|       .| ...|  |     | .|. ..
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECK

MILRRMLEFDPN
 ..||||..|..
DLIRRMLQYDEK
Kinase 89154.m00270.AA ULK 22-262 25 9.1e-57 194.91 In-house 1-317 (329) Show / Hide 
Range on Protein: 22-262
Range on HMM: 1-317/329
Sequence Identity: 25% (81 aa)

YTYIDTIGKGATSIVIKAMNNKT----GKMVACKVVSRL-VLMKLSQ------LEMFEQELRILEKVK----HKN----ICKLYEILYYEEV--IMVVIK
|  .. .|||.   | |. |.||    ...||||....    .|. .      ......| .|. | |    |||    |.|||....      |  .  
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCSNGDLFDYITSLGTVGEVQ----------CYRIILQLAKALSYLHSRKICHRDIKPENIVFDEN------------MIPKLIDFGISTEVLNN----A
||  |||..||   .. .| .          .  .. |.. .. .||...| ||||||.||  ...            .. |. ||| .  | |.    .
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

RKNHCS------GTFLYCPPECFN----SVQFDPMAADIWSLGMTLYTMLFGCFP---WKEQSED-----EIVNF-------ISTTQITVP-----PTCS
    |.      || ||  |. ..      ...   .||||||. .| ||.|  |   |  ....     . .|        | ....  |     |..|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

QRMRMILRRMLEFDPNLR
. .. ..||||..|.. |
PECKDLIRRMLQYDEKDR
Kinase 89154.m00270.AA Ciliate-E2-Unclassified 22-270 21 1.8e-54 187.32 In-house 1-348 (352) Show / Hide 
Range on Protein: 22-270
Range on HMM: 1-348/352
Sequence Identity: 21% (76 aa)

YTYIDTIGKGATSIVIKAMNNKTGKMV-----ACKVVSRLVLMKLSQLEMFEQELRILEKVK-----------------HKNICKLYEILY--YEEVIMV
|. | .||.|. ..| |. ..|..  .     ..|. .. .. ....   . .|. .... |                 |......... .   .. |  
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VIKYCSNGDLFDYITSLGT-----------------VGEVQCY-----RIILQLAKALSYLHSRK-ICHRDIKPENIVFDENM---IPKLIDFGISTEVL
|  || .|||..||.. ..                 . | |.      ... |. ..|.|||. . |.|||||||||.||.|.    .|.|||||| .  
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

NN----------------ARKNHCSGTFLYC----PPECFNSVQFDPM---AADIWSLGMTLYTMLFGCFPWKEQSEDE-------------IVNFISTT
.|                 . ....||  |     .||.. . . | .   ..||||||. || |||| .| . .....             . ....  
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

Q---------------ITVPPTCSQRMRMILRRMLEFDPNLRPSADDLVN
.                ...|..    . .|..||. .|| |...... |
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILN
Kinase 89154.m00270.AA TKL 28-272 17 7.3e-53 181.94 In-house 1-364 (364) Show / Hide 
Range on Protein: 28-272
Range on HMM: 1-364/364
Sequence Identity: 17% (65 aa)

IGKGATSIVIKA-MNNKT-------GKMVACKVVSRLVLMKLS------------------------QLEMFEQELRILEKVKHKNICKLYEILYYEEV-
||.|. ..| |.  .. .       || || |. ..   .. .                          . .|.|.... . .| ||.... .  ...  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------IMVVIKYCSNGDLFDYITSLGTVGEVQCYRIILQLAKALSYLHSRK--------ICHRDIKPENIVFDENMI--------------PK
            .. |  ||..|.|..|..        |  |..|. |....||||..        | |||.|..||  |||.               .|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

LIDFGISTEV--------------------LNNARKNHCSGTFLYCPPECFNSVQFDPMAA---------------DIWSLGMTLYTMLFGCFPWKEQSE
. |||.|...                    .|. ..... ||. ...||...  .... ..               |..| |. |. .| .| |.... .
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY

DEIV------NFISTTQI-----TVP------------PTCSQRMRMILRRMLEFDPNLRPSADDLVNLI
....       ...         ..|            |.| ..|. .. .  . ||. |||.....  .
MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 89154.m00270.AA MELK 22-270 32 6.3e-48 161.73 In-house 1-250 (254) Show / Hide 
Range on Protein: 22-270
Range on HMM: 1-250/254
Sequence Identity: 32% (82 aa)

YTYIDTIGKGATSIVIKAMNNKTGKMVACKVVSRLVLMKLSQLEMFEQELRILEKVKHKNICKLYEILYYEEVIMVVIKYCSNGDLFDYITSLGTVGEVQ
|   |.|| |  . |  |    |..||| |.. .  |   . |   . |.  | ...|..||.|| ..  |. |..|. ||. |..|||| .   . | .
YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQLG--HDLPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEE

CYRIILQLAKALSYLHSRKICHRDIKPENIVFDENMIPKLIDFGISTEVLNNARKNH----CSGTFLYCPPECFNSVQFDPMAADIWSLGMTLYTMLFGC
   .  |.  |..|.||.   |||.||||..|||..  ||||||.        .  |    | |   |  ||  .  |.    ||.||.|. ||... | 
TRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKT-KGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGF

FPWKEQSEDEIVNFISTTQITVPPTCSQRMRMILRRMLEFDPNLRPSADDLVN
 |. .     .   |      .|.  |   . .||.||  ||. | |  .|.|
LPFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLN
Kinase 89154.m00270.AA STE 22-272 23 1.5e-47 164.33 In-house 1-359 (359) Show / Hide 
Range on Protein: 22-272
Range on HMM: 1-359/359
Sequence Identity: 23% (85 aa)

YTYIDTIGKGATSIVIKAMNNK---------------TGKMVACKVVS----R----------LVLMKLSQLEMFEQELRILEKVK--HKNICKLYEILY
.. |. |||||.  | ||||.|               ||...| |...    .          |  .  .... ...|..|. | .  |.|| | |   .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

YE-------EVIMVVIKYCSNGDLFDYITSLGTVG--------------EVQCYRIILQLAKA-LSYLHSRKICHRDIKPENIVFDENMIPKLIDFGIST
.|       . . ..  |...| | | | . . .|              | |  .|. |. |. |.|||| .| |||||| || .      ||.|||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

EVLN----------------NA-RKNHCSGTFLYCPPECFNSVQFDPM------AADIWSLGMTLYTMLFGCFPWKEQSEDEIVNFISTTQ---------
 . .                .. . |.. ||  .  ||  .  . .         .|||||| |.  |. |. || . .  .    | . .         
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

----ITVP--PT--------------------CSQRMRMILRRMLEFDPNLRPSADDLVN----LI
     . |  |.                    .|. ..  ... |. ||| ||.|..| .     |
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 89154.m00270.AA TyrKc 22-272 23 1.9e-17 59.48 SMART 1-280 (280) Show / Hide 
Range on Protein: 22-272
Range on HMM: 1-280/280
Sequence Identity: 23% (68 aa)

YTYIDTIGKGATSIVIKAMNNKTGKMVACKVVSRLVLMKLSQLEMFEQELRILEKV--KHKNICKLYEILYYE-------EVIMVVIKYCSNGDLFDYIT
 | ....| ||  .| |.. .    .|| |..          .|.| .|.||. |.  .|.|| .|| .   .       | .|.|  |...||| ||. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

SLGT-VGEVQCYRIILQLAKALSYLHSRKICHRDIKPENIVFDENMIPKLIDFGISTEVLNN-------ARKN-----HCS--GTFLYCPPECFNSVQFD
. .  .   .   . .| |.  .||||... |||.   |.  .|| . |  ||| | .. .          .      ..        ..|||.|   | 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

PMAADIWSLGMTLYTML-FGCFPWKE-----QSEDEIVNFISTT-QITVPPT--------CSQRMRMILRRMLEFDPNLRPSADDLVNLI
. . |.|| | ... .. .|  |. .      | .|..... .      ||         |.. | .| ..  ..||. ||.  ... ..
T-KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 89154.m00270.AA Pkinase_Tyr 22-146 27 1.7e-11 39.55 Pfam 1-137 (270) Show / Hide 
Range on Protein: 22-146
Range on HMM: 1-137/270
Sequence Identity: 27% (38 aa)

YTYIDTIGKGATSIVIKAMNN----KTGKMVACKVVSRLVLMKLSQ--LEMFEQELRILEKV-KHKNICKLYEILY-YEEV--IMVVIKYCSNGDLFDYI
 | . ..|.||   | |.  .    .|.  || |..        .|  .|.| .|..|. .  .|.|| .|| . .  .|   |..|  |. .||| || 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

TS----LGTVGEVQCYRIILQLAKALSYLHSRKICHRDI
 .     . .   .   . .| ||...||.|... |||.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL
Kinase 89154.m00270.AA Pkinase_Tyr 200-272 18 0.000276 15.14 Pfam 194-270 (270) Show / Hide 
Range on Protein: 200-272
Range on HMM: 194-270/270
Sequence Identity: 18% (14 aa)

AADIWSLGMTLYTMLFGC-FP-WKEQSEDEIVNFI--STTQITVPPTCSQRMRMILRRMLEFDPNLRPSADDLVNLI
. |.|| | ... ..  .  | ... |  |....|  .  .   |. |.. . .....  ..||. ||.  .... .
KSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL