Gene 85284.m00040 (T.vaginalis)

85284.m00040

Species: T.vaginalis
Alias: TvagK0045, 85284.m00040
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
85284.m00040.AA Protein None 373 None Fasta, JSON
85284.m00040.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of 85284.m00040.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 85284.m00040.AA CAMKL 17-267 32 5.8e-98 313.22 In-house 1-297 (297) Show / Hide 
Range on Protein: 17-267
Range on HMM: 1-297/297
Sequence Identity: 32% (96 aa)

YVFDEVIGSGSFSTVYKGHQ-LQTNKTVAIKVVKRNRLD-AESSRKF------------YSEARILSNLV---HPHIVRFIALMQDDDC------EFLIM
| . ...| |||..|  ..  . |.. ||||.......   . ..|             . |..|.. |    ||.|...   ......       .|.|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYVSGES--LRDLLERKTH----LSENQSRRYFIQILSALEYFHNTTQLLHRDLKVDNIMIDHSD--NIRIIDFGLAGKYDE--NDPNR----FCGSPKY
||.|| .  | | .... |    ..|.. |||| ||.||..| |.     |||.| .||..|...  || |||||.. .|..  . |..    ||||| |
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHG-IVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

VSPEIYKR--VPYT-EKADIWSLGVILYLMTVGSLPFIADTLP-------MLSFAVRVSEPTFP--PTMTPSLRQLLISMLEKDPENRPTIEKIRMSRWL
 .|||...   ||   |.||||.||||| | .| ||| .||..        |   ...    .|  . .  ..|.|. .||...|| ||||. |.. .|.
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 85284.m00040.AA CAMK 22-267 22 2.4e-91 294.52 In-house 1-425 (425) Show / Hide 
Range on Protein: 22-267
Range on HMM: 1-425/425
Sequence Identity: 22% (95 aa)

VIGSGSFSTVYKGHQLQTN------------KTVAIKVVKRNRLD-------------------------AESSRK-FYSEARILSNLV-------HPHI
..|.|||..|... . .|.            . ||||......|.                          ...|| ...| .|...|        ||.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRFIALMQD-------------------DDCEFLIM---EYVSGE----SLRDLLERKTH---------------LSENQSRRYFIQILSALEYFHNTTQ
....  ..|                   |.. ...|   ||.||      | | . ....               ..| . |||| ||.||..| |.   
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN-

LLHRDLKVDNIMIDHSD-----------------NIRIIDFGLAGKYDENDPNR-------------------------FCGSPKYVS-PEIYKR-----
  ||||| .||..|...                 || |||||.| |.|... |.                         |||.| |.. ||. ..     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------VPYTEKADIWSLGVILYLMTVGSLPFIAD-------------TLPMLSFAVRVSEPTFPPTMTPS------------------------LR
          .|..|.|.||.||||| | .| .|| .|             ... |   ..  . .||| . .                          .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

QLLISMLEKDPENRPTIEKIRMSRWL
.|. .||..|||.|.||| .    |.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 85284.m00040.AA MARK 17-267 35 2.3e-86 282.33 In-house 1-262 (262) Show / Hide 
Range on Protein: 17-267
Range on HMM: 1-262/262
Sequence Identity: 35% (94 aa)

YVFDEVIGSGSFSTVYKGHQLQTNKTVAIKVVKRNRLDA-ESSRKFYSEARILSNLVHPHIVRFIALMQ--DDDC-EFLIMEYVSGESLRDLLERK--TH
| .  .|| ||...|.... . |.. ||||......|.  .. .....|..|.. | ||.|...   ..  .  .  .|||||.|| .|.| .. .   .
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LSENQSRRYFIQILSALEYFHNTTQLLHRDLKVDNIMIDHSD--NIRIIDFGLAGKYDEND-PNRFCGSPKYVSPEIYKRVPYT-EKADIWSLGVILYLM
|.|.  ||.| ||.||..| |.     |||.| .||.||.    || |||||.. .  ..   |.|||.| | .||| .. ||.  |.|||||||.|| |
LHEEEARRIFRQIVSAVNYCHSKN-IVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM

TVGSLPFIADT--LPMLSFAVRVSEPTFPPTMTPSLRQLLISMLEKDPENRPTIEKIRMSRWL
..|..|| .||  .  | . ..  ....|. . ...|.|. ..|  .|| ||||| | . .|.
VCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 85284.m00040.AA S_TKc 17-267 32 6.2e-86 292.71 SMART 1-231 (231) Show / Hide 
Range on Protein: 17-267
Range on HMM: 1-231/231
Sequence Identity: 32% (86 aa)

YVFDEVIGSGSFSTVYKGHQLQTNKTVAIKVVKRNRLDAESSRKFYSEARILSNLVHPHIVRFIALMQDDDCEFLIMEYVSG--ESLRDLLERKTH----
| . ..||.|.|..|||..   |.. ||||..|         .....| .||..  ||.||...  .|| |. ...|||..|   .|.|..... .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LSENQSRRYFIQILSALEYFHNTTQLLHRDLKVDNIMIDHSDNIRIIDFGLAGKYDENDPNRFCGSPKYVSPEIYKRVPYTE-KADIWSLGVILYLMT
  ..| . |.|. ||..|||| |.  . .||||| .||..|.  .| |.||||| ..     . |||.| |..||.    .|.  |.|.||.|.||| | 
FPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

VGSLPFIADTLPMLSFAVRVSEPTFPPTMTPSLRQLLISMLEKDPENRPTIEKIRM-------SRWL
.|  ||   .. |.   ..          .|......  .|.||||.|||. ..           |.
CGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 85284.m00040.AA AGC 17-267 22 1.8e-78 201.65 In-house 1-395 (395) Show / Hide 
Range on Protein: 17-267
Range on HMM: 1-395/395
Sequence Identity: 22% (90 aa)

YVFDEVIGSGSFSTVYKGHQL------QTNKTVAIKVVKRNR--------LDAESSRK--------FYSEARILSNLV----------HPHIVR-FIALM
. |  ||| |||..||           .|.|  |.||.|  .          .   .         . .| .||...           || ||.      
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDDDC--EFLIMEYVS----------G-ESLRDLLE--RKTHLSENQSRRYFIQ-------ILSALEYFHNTTQLLHRD-LKVDNIMIDHSDNIRIIDFG
||.|    ...|||..          | |..  | .  .. ...|...| |. .       |..|||| |.     ||| || .||..|.  .|.. |||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LAGK--------------------------------------YDEND--------------PNRFCG--SPKYVSPEIYKRVPYTEKADIWS--LGVILY
|. .                                       ..|                . |||  .| |..|||     |.  .|.||  ||...|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

LMTVGSLPFIADTL---------PMLSFAVRV-------SEPTFP----------PTMTPSLRQLLISMLEKDPENRPT----------IEKIRMSRWL
 | .|  || .|.          ||  |            ...||          . ..| .. |.  .|.||||.|..          .| |.   | 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 85284.m00040.AA Pkinase 17-267 31 9.5e-75 259.44 Pfam 1-293 (293) Show / Hide 
Range on Protein: 17-267
Range on HMM: 1-293/293
Sequence Identity: 31% (93 aa)

YVFDEVIGSGSFSTVYKGHQLQTNKTVAIKVVKRNRLDAESSRKFYS--EARILSNLVHPHIVRFIALMQDDDCEFLIMEYVSGE----SLRDLLE--RK
|.. ..||||||..|||.|   |.|.||.|..|. . . .  .      |..|. .| ||.|||..  ..|.|   ..|||. |     .| |...  |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

THL--SENQSRRYFIQILSALEYFHNTTQLLHRDLKVDNIMIDHSDNI----RIIDFGLAGK--YDENDPNRFCGSPKYVSPEIYK-RVPYTEKADIWSL
. .  ||.. ..|. |||..||| |.    .||||| .||.||. ..|    .|.||||| .  |  | .. |||.| |..||. . . .|. |.|.||.
GCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVILYLMTVGSLPFIAD-----------TLPMLSFAVRVSEPTFPPTMT----------------PSLRQLLISMLEKDPENRPTIEKIRMSRWL
|.||| |  | .||  .               ..  .. ..|.  . ..                ....... ..|.|||. |||.| |  . |.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 85284.m00040.AA AMPK 17-267 36 3.1e-70 207.75 In-house 1-254 (254) Show / Hide 
Range on Protein: 17-267
Range on HMM: 1-254/254
Sequence Identity: 36% (92 aa)

YVFDEVIGSGSFSTVYKGHQLQTNKTVAIKVVKRNRL-DAESSRKFYSEARILSNLVHPHIVRFIALM-QDDDCEFLIMEYVSGESLRDLLERKTHLSEN
|. .. || |.|  |  |   .|.. ||||.  . .. | . . .  .| .||  . ||||..         .. |..||||||  | |   ... |.| 
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

QSRRYFIQILSALEYFHNTTQLLHRDLKVDNIMIDHSDNIRIIDFGLAGKYDENDPNR-FCGSPKYVSPEIYKRVPYT-EKADIWSLGVILYLMTVGSLP
...|.| ||.|..|| |.     |||||  |. .||  || | ||||   . ...  .  |||| | .||.    .|   . |||| ||||| |  | ||
EACRFFQQIISGVEYCHR-HMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLP

FIADTLPMLSFAVRVSEPTFPPTMTPSLRQLLISMLEKDPENRPTIEKIRMSRWL
|  .  |.|   ..  |.. |  ..|. ..|. .||..||..| ||. || . |.
FDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 85284.m00040.AA Ciliate-E2 17-267 25 1.2e-69 237.75 In-house 1-365 (365) Show / Hide 
Range on Protein: 17-267
Range on HMM: 1-365/365
Sequence Identity: 25% (96 aa)

YVFDEVIGSGSFSTVYKGHQLQT-----------------------NKTVAIKVVKRNRLDAESS-RKFY----------SEARILSNLVHPHIVRFIAL
| | ..||.|.|..|||. . ..                       .| .|.|..| | . . ..  . .           | .||..| ||.|....  
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

MQ--DDDCEFLIMEYVSGESLRDLLE-----RKTH------LSENQSRRYFIQILS---------------ALEYFHNTTQLLHRDLKVDNIMIDHSDNI
 |  ||.. .|.|||..| .|.|...     |. .      ..|.. .... |||.               |||| |.    .|||.| .||..     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

RIIDFGLAGKYDENDPNR---------------------------------FCGSPKYVSPEIYKRVP---------YTEKADIWSLGVILYLMTVGSLP
 ||||||. |||..  ||                                 .||.| |..|||... .         |..|.|||||||||| |  | .|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FIADTLPMLSFAVRVS-EPTFPPT------------------MTPSLRQLLIS----MLEKDPENRPT-IEKIRMSRWL
|         .      .  ||.                    ...  .|.      ||.||||.|.| .|.|    |.
F---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 85284.m00040.AA Ciliate-E2-Unclassified 17-267 25 8.6e-67 228.21 In-house 1-352 (352) Show / Hide 
Range on Protein: 17-267
Range on HMM: 1-352/352
Sequence Identity: 25% (91 aa)

YVFDEVIGSGSFSTVYKGHQLQTN--------KTVAIKVVKR--------NRLDAESSRKFYSEAR--------ILSNLVHPHIVRFIALMQDDDCEFLI
| . ..||.|.|..|||  . ...        | . |. .|         | .... ..|  .  |        ||.|. ||.||...   ||... ...
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEYVSGESLRDLLERKTH-----------------LSENQSR-----RYFIQILSALEYFHNTTQLLHRDLKVDNIMIDHSD---NIRIIDFGLAGKYDE
|||. | .|.. .. . .                 ..|.|..     .|| |||..||| |     .|||.| .||..| .    .|.|||||.. ||..
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

N--------------DPNRF---CGSPKYV----SPEIYKRVPYT----EKADIWSLGVILYLMTVGSLPFIADT-------------------LPMLSF
|              .....   ||.| |     .||....  |     .|.|||||||||| |  | .|| . .                   |    .
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

AVRVSEPTFPP-----TMTPSLRQLLI----SMLEKDPENRPTIEKIRMSRWL
.  .. | ||.     .  |.   ..     .||.|.|..|.|.|.|    |.
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 85284.m00040.AA ULK 17-267 24 1.4e-61 210.88 In-house 1-324 (324) Show / Hide 
Range on Protein: 17-267
Range on HMM: 1-324/324
Sequence Identity: 24% (81 aa)

YVFDEVIGSGSFS-TVYKGHQLQT---NKTVAIKVVKRNRLDAESSR--------KFYSEARILSNLV---HPH--IVRFIALMQDDDC--EFLIMEYVS
|. ....|.|||  .||||   .|   |. ||.|.. .. .   ...        .. .| .|.  |    ||.  ||...   .....   ..||||  
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GESLRDLLERKTH---------LSENQSRRYFIQILSALEYFHNTTQLLHRDLKVDNIMIDHSDN------------IRIIDFGLAGKYDEN-DPNRFC-
|  |....... .         |||.. . .|.||.... . |.  .  |||.| .||.| . .             . | |||.| . |.|      | 
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHK-HNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

---------GSPKYVSPEIYK----RVPYT-EKADIWSLGVILYLMTVGSLPFIADTLPMLS--------------FAVRVSEPTFP-----PTMTPSLR
         |.| | .|.| .    . ||.  |.||||||.|.| |  |. || ..    .               . ..     ||     |   | ..
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECK

QLLISMLEKDPENRPTIEKIRMSRWL
.|.  ||..|.. | ..| |    |.
DLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 85284.m00040.AA ULK 17-267 24 9.9e-60 204.75 In-house 1-329 (329) Show / Hide 
Range on Protein: 17-267
Range on HMM: 1-329/329
Sequence Identity: 24% (80 aa)

YVFDEVIGSGSFSTVYKGHQLQT----NKTVAIKVVKRNRLDAESSR--------KFYSEARILSNLV--------HPHIVRFIALMQDD--DCEFLIME
|. ....|.||| .||||   .|    |. ||.|.. .. .. ..           . .| .|.  |         ||.||...   ...  .. ..|||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YVSGESLRDLLERKTH----------LSENQSRRYFIQILSALEYFHNTTQLLHRDLKVDNIMIDHSDN------------IRIIDFGLAGKYDEN----
|  |  |....... .          |||.. . .|.|||... . |   .  |||.| .||.|.  .             . | |||.| . |..    
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHK-HNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQ

-DPNRFC------GSPKYVSPEIYK----RVPYT-EKADIWSLGVILYLMTVGSLPFIADTLPML-----SF---------AVRVSEPTFP-----PTMT
 .   .       |.| | .|.| .    . ||.  |.||||||.|.| | .|  || |   .       .          ...   . ||     |.  
QMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

PSLRQLLISMLEKDPENRPTIEKIRMSRWL
| ...|.  ||..|.. | ..| .    |.
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 85284.m00040.AA QIK 17-267 34 2.5e-59 203.43 In-house 1-272 (272) Show / Hide 
Range on Protein: 17-267
Range on HMM: 1-272/272
Sequence Identity: 34% (95 aa)

YVFDEVIGSGSFSTVYKGHQLQTNKTVAIKVVKRNRLDAESSRKFYSEARILSNLVHPHIVRFIALMQDDDCEFLIMEYVSGESLRDLLERKTH------
|  .  || | | .|  .    | . ||||.. . .||.|   | | |  |.  | ||||..    |  ||  ....|| |.  . | |  . .      
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMV

--------------LSENQSRRYFIQILSALEYFHNTTQLLHRDLKVDNIMIDHSDNIRIIDFGLAGKYDEND-PNRFCGSPKYVSPEIYKRVPYT-EKA
              ..||. || | ||.|| .| |.  .  |||||  ||..|   || |.|||.   . .    . .|||| |  ||. .   |.  |.
NSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHK-RNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKV

DIWSLGVILYLMTVGSLPFIADTLPMLSFAVRVSEPTFPPTMTPSLRQLLISMLEKDPENRPTIEKIRMSRWL
||||.||.|| .  |.|||. .||. |   | .     |. |   . .|   ||  ||| | ||. |.  ||.
DIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase 85284.m00040.AA TyrKc 17-266 24 6.5e-26 93.33 SMART 1-280 (280) Show / Hide 
Range on Protein: 17-266
Range on HMM: 1-280/280
Sequence Identity: 24% (71 aa)

YVFDEVIGSGSFSTVYKGHQLQTNKTVAIKVVKRNRLDAESSRKFYSEARILSNL--VHPHIVRFIALMQDD-------DCEFLIMEYVSGESLRDLLER
 ......|.| | .||||.      .||.|..| .       . |..||||...|   ||.|||...   ..       .  ...|||... .|.| | .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KTH-LSENQSRRYFIQILSALEYFHNTTQLLHRDLKVDNIMIDHSDNIRIIDFGLAGKYDEN-------DPNRF----CG---SP-KYVSPEIYKRVPYT
. . |.  .   . .|| .  || |   .. ||||   |.....   ..| ||||. . ..        |  |     .|    | .  .||  .   .|
HRPKLCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

EKADIWSLGVILY-LMTVGSLPFIA-----DTLPMLSFAVRVS-EPTFPPT--------MTPSLRQLLISMLEKDPENRPTIEKIRMSRW
.| |.|| || .. ..| |  |         .   .   |.    .  ||         ... . |.  .  . |||.||| . |  ...
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase 85284.m00040.AA Pkinase_Tyr 17-204 27 1.2e-24 84.12 Pfam 1-205 (270) Show / Hide 
Range on Protein: 17-204
Range on HMM: 1-205/270
Sequence Identity: 27% (57 aa)

YVFDEVIGSGSFSTVYKGHQL----QTNKTVAIKVVKRNRLDAES--SRKFYSEARILSNL-VHPHIVRFIALMQ-DDDC--EFLIMEYVSGESLRDLLE
 .|....|.|.| .||||.      .|. .||.|.. ..  . |   ...| .||.|...|  ||.|||...    ...    ...|||. . .|.| | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

R----KTHLSENQSRRYFIQILSALEYFHNTTQLLHRDLKVDNIMIDHSDNIRIIDFGLAGKY-----D-ENDPNRFCGSPKYVSPE-IYKRVPYTEKAD
.    | .|.  .   . .|| ...|| ..   . ||||   |......  ..| |||||              .      |  .|| |  .. .|.| |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKN-CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGK-FTTKSD

IWSLGVILY
.|| || ..
VWSFGVLMW
Kinase 85284.m00040.AA APH 134-166 29 1.4e-05 19.87 Pfam 170-206 (248) Show / Hide 
Range on Protein: 134-166
Range on HMM: 170-206/248
Sequence Identity: 29% (11 aa)

TQLLHRDLKVDNIMID-HSDNIR---IIDFGLAGKYD
....|.|.. .|.|.| ..|. |   .||.. |.  |
PCWCHGDFHPGNVMWDPRPDGGRVTGVIDWDDACWGD
Kinase 85284.m00040.AA APH 47-131 18 0.001099 13.45 Pfam 25-111 (248) Show / Hide 
Range on Protein: 47-131
Range on HMM: 25-111/248
Sequence Identity: 18% (17 aa)

VVKRNRLD--AESSRKFYSEARILSNL-VHPHIVRFIA---LMQDDDCEFLIMEYVSGESLRDLLERKTH-LSENQSRRYFIQILSALEYFH
|..|.. .  ||. .... ..| |... ..... | ..   . ..    ...||.. ||.|..      | |...|..... ..  .|  .|
VLRRYPPPWWAEELHREHRWLRHLAAHGIPVPVPRVLWGCTDDEFHGWPWYLMEWLPGEDLWRW-----HALHCAQRPALLEALARFLARLH