Gene 94466.m00030 (T.vaginalis)

94466.m00030

Species: T.vaginalis
Alias: TvagK0566, 94466.m00030
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag2

Sequence

Name Sequence Type Origin Length Description Download
94466.m00030.AA Protein None 325 None Fasta, JSON
94466.m00030.kin_dom Protein Kinase Domain None 249 None Fasta, JSON

Protein domain

Protein domains of 94466.m00030.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 94466.m00030.AA S_TKc 16-272 29 2.2e-73 251.04 SMART 1-231 (231) Show / Hide 
Range on Protein: 16-272
Range on HMM: 1-231/231
Sequence Identity: 29% (79 aa)

YVLQEELGLGAFSTVFLAIHSKTGEKVAIKVIDRNTATETDMIVYVENELRIQSRLNHPNIAKVYDVIYTPEIIAIVMEYMPN--GDMQMLINNNFI---
| . ...| |||..|....| |||..||||.|.            ...|..| .. .|||| | |||... . . .||||...  ||.  .| ..     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FKQSEQIRIAIELLDALNYLHEKGISHRDIKTANILFDKDMHPKLIDFGFSREFSAKMKTYCGTHLLMAPEIISNKVYNGMKADIWAYGVTMHIMAT
   |   .  ... ....||.|.|..|| |||.| .|||.|.  | |..|||..|..    .|.|||   ||||..    |.. |.|.|. |... .|..
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

HCYPFSYQNDAQFLADVRNKTIKVNNTAEGNLGW-LINRSLQFDPDNRPTAQSMLD-YMKVQSTAFA
 . ||.  .... .  ..              .. .|.. ||.||..||||   |   ... .  . 
GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 94466.m00030.AA CAMK 21-258 21 1.8e-71 229.38 In-house 1-417 (425) Show / Hide 
Range on Protein: 21-258
Range on HMM: 1-417/425
Sequence Identity: 21% (90 aa)

ELGLGAFSTVFLAIHSKTG------------EKVAIKVIDRNTATE-------------------------TDMIVYVENELRIQSR-------LNHPNI
.|| |.|..|.|.|| .|.            .|||||.||.. ...                           .   |..|..| ..       |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

AKVYDVIYTPEI-------------------IAIVM---EYMPNG----DMQMLINNN---------------FIFKQSEQIRIAIELLDALNYLHEKGI
 | |.|. .|.                    . .||   ||...|    |.   |  .               . |. .|  |.   ...|..|.|...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

SHRDIKTANILFDKDM-----------------HPKLIDFGFSREFSA--------------------------KMKTYCGTHLLMA-PEIISN------
 |||.|  |||.|...                   |.|||||...|                            ||||.|||   || ||...       
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------KVYNGMKADIWAYGVTMHIMATHCYPFSYQ-------------NDAQFLADVRNKTIK-VNNTAEG-----------------------NLGW
       | | | |.|.|. || . || . ..||                || . .  ...           .                           
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LINRSLQFDPDNRPTAQ
||.. || ||..|.|..
LIRKMLQVDPEKRMTIE
Kinase 94466.m00030.AA CAMKL 16-212 36 1.1e-70 224.73 In-house 1-236 (297) Show / Hide 
Range on Protein: 16-212
Range on HMM: 1-236/297
Sequence Identity: 36% (87 aa)

YVLQEELGLGAFSTVFLAIH-SKTGEKVAIKVIDRNTATE-------------TDMIVYVENELRIQSRLN---HPNIAKVYDVIYTPEI------IAIV
| . ..|| |.|..| ||.| . ||||||||.||.. ...              ..   .. | .|...||   |||| | |.||.|||       | .|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

MEYMPNGD--MQMLINNNFI----FKQSEQIRIAIELLDALNYLHEKGISHRDIKTANILFDKDM--HPKLIDFGFSREFSA-------KMKTYCGTHLL
||| ..|.  ..  | ..      .. .|  |.   ...|.||.|..|| |||||  |||.|...    |.|||||| ..         |.|| ||.   
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

MAPEIISN--KVYNGMKADIWAYGVTMHIMATHCYPF
|||||..   | |.| |.|||. ||..  | .  .||
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPF
Pkinase 94466.m00030.AA Pkinase 16-264 27 3.8e-66 230.85 Pfam 1-293 (293) Show / Hide 
Range on Protein: 16-264
Range on HMM: 1-293/293
Sequence Identity: 27% (81 aa)

YVLQEELGLGAFSTVFLAIHSKTGEKVAIKVIDRNTATETDMIVYVE-NELRIQSRLNHPNIAKVYDVIYTPEIIAIVMEYMPNG----DMQMLIN--NN
|.. . .| |.|..|....| .||..||.|.|.. .. .   .  .  .|..|  ||||||| . ||. ...  | .||||...|    |   .|   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

FIF--KQSEQIRIAIELLDALNYLHEKGISHRDIKTANILFDKDMHP----KLIDFGFS----REFSAKMKTYCGTHLLMAPEIISNKVYNGMKADIWAY
  |     | .... ..| .|.|.|..|| |||.| .|||.|...|.    |..|||..       .  |.|.|||   ||||.|    | | |.|.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVTMHIMATHCYPFSYQ------NDAQFLADVRNKTIKVNNTAE---------------------GNLGWLINRSLQFDPDNRPTAQSMLDY--M
|.....|..   ||. .      .. | .. .. . .. .   .                      ..  .|.. |..||  ||||.  |    .
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 94466.m00030.AA AGC 16-213 22 8.4e-63 160.21 In-house 1-306 (395) Show / Hide 
Range on Protein: 16-213
Range on HMM: 1-306/395
Sequence Identity: 22% (70 aa)

YVLQEELGLGAFSTVFLAIHS------KTGEKVAIKVIDRNT-ATETD--MIVYVENE------------LRIQSRLN----------HPNIAK-VYDVI
. .   .| |.|..|.|. .        ||.  |.||..  .   ...  |. .. .|             .| ...|          ||.| |  .   
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

YTPEI--IAIVMEYMP--------NGD-MQMLIN----NNFIFKQSEQIRIAIE-------LLDALNYLHE-KGISHRD-IKTANILFDKDMHPKLIDFG
 ...   . .||||||         |. . .|..    ....|  ..   .| |       .. || |||. .|| ||| .|  |||.|.| | || |||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

FSREFS-----------------------------------------------------AKMKTYCG--THLLMAPEIISNKVYNGMKADIWA--YGVTM
.. |.                                                      .. .| ||  |.  |||||.      |  .|.|.  .|. |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCLM

HIMATHCYPFS
  | | . ||.
YEMLTGYPPFY
Kinase 94466.m00030.AA MARK 16-212 36 7.1e-62 201.1 In-house 1-206 (262) Show / Hide 
Range on Protein: 16-212
Range on HMM: 1-206/262
Sequence Identity: 36% (79 aa)

YVLQEELGLGAFSTVFLAIHSKTGEKVAIKVIDRNTATETDMIVYVENELRIQSRLNHPNIAKVYDVIY--TPEI-IAIVMEYMPNGDMQMLINNN----
| .  ..| |....| ||.| .||.|||||.....  ..   .  |. |..| ..|.|||| | ..||   |..  | ..||| ..|..   | .     
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

-------FIFKQSEQIRIAIELLDALNYLHEKGISHRDIKTANILFDKDM--HPKLIDFGFSREF--SAKMKTYCGTHLLMAPEIISNKVYNGMKADIWA
        ||.|         .. |.||.|.|.| |||||  ||| |...    |.||||||...    | .| |||   |||||.. | |.| |.|||.
LHEEEARRIFRQ---------IVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWS

YGVTMHIMATHCYPF
 || . .| . ..||
LGVVLYFMVCGYFPF
Kinase 94466.m00030.AA Ciliate-E2 16-258 23 4e-57 194.62 In-house 1-357 (365) Show / Hide 
Range on Protein: 16-258
Range on HMM: 1-357/365
Sequence Identity: 23% (88 aa)

YVLQEELGLGAFSTVFLAIHSKTGEKVAIKVIDRNT------------------ATETDMIVYVENELRIQ----------------SRLNHPNIAKVYD
| ... .| |.|..|... . |.....|||.|| .                     . ..| ....|..|                 ..|||||| | |.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

VIY--TPEIIAIVMEYMPNGDMQMLINNNFIFKQSE----------QIR-IAIELLD---------------ALNYLHEKG-ISHRDIKTANILFDKDMH
. .  . . | .||||   ||.. .|.|| .....|          .|. |  ..|.               ||.|||.|. | |||||  ||||     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

PKLIDFGFSREFSAK----------------------------------MKTYCGTHLLMAPEIISNKVYNG--------MKADIWAYGVTMHIMATHCY
.|.||||.|.... .                                   .|.|||   |||||...| |..         |.|||. ||....| .  .
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFSYQNDAQFLADVRNKTIKVNNT--------AEGNLGW------------LINR----SLQFDPDNRPT-AQ
||        .    .. |. ..             ..|            ||..     || ||..|.| ..
PF--------QQQIKQCKIDFPCPEWQKDTQCI-Q-CKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWE
Kinase 94466.m00030.AA ULK 16-254 26 5.9e-55 188.88 In-house 1-312 (324) Show / Hide 
Range on Protein: 16-254
Range on HMM: 1-312/324
Sequence Identity: 26% (82 aa)

YVLQEELGLGAFS-TVFLAIHSKT---GEKVAIKVID----RNTATE------TDMIVYVENELRIQSRLNHPN--IAKVYDVIYTPEI--IAIVMEYMP
|.| ..|| |.|  .|. ... ||   ...||.|.||    ..   |       ... .. .....  .|.|||  | | ||. .|.    | |.||| .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGDMQMLINNN---------FIFKQSEQIRIAIELLDALNYLHEKGISHRDIKTANILFDKD------------MHPKLIDFGFSREFS------AKMKT
 || . .|..|          .. ..| | . . .. .. .||...| ||||| .|||  ..             . |. ||||.. .        ...|
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

YC------GTHLLMAPEIIS----NKVYNGMKADIWAYGVTMHIMATHCYPFSYQ-NDAQ----FLAD--------VRNKTIKVN-----NTAEGNLGWL
..      || | |||.|..    .| |.  |.|||  |. .. | .  |||. . || .     | .        ..|. |. .     .    ..  |
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDL

INRSLQFDPDNR
| | ||.|.. |
IRRMLQYDEKDR
Kinase 94466.m00030.AA ULK 16-213 29 1.9e-54 187.19 In-house 1-257 (329) Show / Hide 
Range on Protein: 16-213
Range on HMM: 1-257/329
Sequence Identity: 29% (77 aa)

YVLQEELGLGAFSTVFLAIHSKT----GEKVAIKVID----RNTATETD---MIVYVENELRIQSRLN--------HPNIAKVYDVIYTPEI--IAIVME
|.| ..|| |.| .|. ... ||    .||||.|.||    ..   | .   |.  ..|| .|. .|.        |||| | ||. .|.    | |.||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YMPNGDMQMLINNN----------FIFKQSEQIRIAIELLDALNYLHEKGISHRDIKTANILFDKD------------MHPKLIDFGFSREFSAK-----
| . || . .|..|           .. ..| | . . .| .. .||...| ||||| .||| ...            .. |. ||||.. ..       
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-MKTYC------GTHLLMAPEIIS----NKVYNGMKADIWAYGVTMHIMATHCYPFS
 |.|.       || | |||.|..    .| |.  |.|||  |. .. | .  .||.
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFY
Kinase 94466.m00030.AA STE 16-266 22 1.4e-52 180.96 In-house 1-359 (359) Show / Hide 
Range on Protein: 16-266
Range on HMM: 1-359/359
Sequence Identity: 22% (83 aa)

YVLQEELGLGAFSTVFLAIHSK---------------TGEKVAIKVIDRNTATE--------------TDMIVYVENELRIQSRLN--HPNIAKVYDVIY
. ..|..| ||| ||..|.. |               ||| .|||... .. .               .. .  ...|..| ...|  |||| | |.  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TP-------EIIAIVMEYMPNGDMQMLINNNFIFKQS------------EQIR--IAIELLDA-LNYLHEKGISHRDIKTANILFDKDMHPKLIDFGFSR
         . . |.||||..|    .|..... ...            |..   |. ..| . |.|||...| ||||| ||||.      ||.|||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

EFSA-------------------KMKTYCGTHLLMAPEIISN-----KVYNGMKADIWAYGVTMHIMATHCYPFSYQNDAQFLADVRNKTIKVN------
 ..                    | .| .||   ||||.|..     .   . |.|||  | |.  ||| ..|..  .. . .    .......      
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---NTAEGNLGW--------------------------LINRSLQFDPDNRPTAQSMLD--YMKV
   ..                                  ||. || ||..||||. .|      .
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 94466.m00030.AA Ciliate-E2-Unclassified 16-258 22 4.4e-52 178.96 In-house 1-344 (352) Show / Hide 
Range on Protein: 16-258
Range on HMM: 1-344/352
Sequence Identity: 22% (77 aa)

YVLQEELGLGAFSTVFLAIHSKTGEKV-----AIKVIDRNTATETDMIVYVENELRIQSR----------------LNHPNIAKVYDVIY--TPEIIAIV
| ... .| |.|..|....|.|.. ..     ..|.....      .. .. ........                ||||.. .|... .  . . | ||
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEYMPNGDMQMLINNN-----------------FIFKQSEQI-----RIAIELLDALNYLHEKG-ISHRDIKTANILFDKDM---HPKLIDFGFSR---E
|||...||..  |...                  ||   . .     ... ..|..|.|||.|. | |||||  |||||...   ..|.||||.|.   .
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

F---------------SAKMKTYCGTHLLM----APEIISNKVYNGM---KADIWAYGVTMHIMATHCYPFSYQNDAQ----------------FLADVR
.               . .|.| |||   |    |||.. .. |...   |.|||. || .. | .  |||...|. |                .. .  
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

NKTIKVNN--------TAEGNLGWLIN----RSLQFDPDNRPTAQ
.| |....        .   .   .||    . |. .|..|.|..
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFE
Kinase 94466.m00030.AA TKL 22-264 19 4.2e-51 176.09 In-house 1-364 (364) Show / Hide 
Range on Protein: 22-264
Range on HMM: 1-364/364
Sequence Identity: 19% (72 aa)

LGLGAFSTVFLAIHSK--------TGEKVAIKVIDRNTATETDMIV------------------------YVENELRIQSRLNHPNIAKVYDVIYTPEI-
.| |.|..|. ...          ||. ||.|.. ..   |....                           |.|... |||.|||| . . .   |.  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------IAIVMEYMPNGDMQMLINNNFIFKQSEQIRIAIELLDALNYLHE--------KGISHRDIKTANILFDKDMH--------------PK
            ..|||||.|.|.   ...       .  .|.|..   ..||||         ..| |||.|..||| |....              .|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

LIDFGFSREFSA----------------------KMKTYCGTHLLMAPEIISNKVYNG---------------MKADIWAYGVTMHIMATHCYPFSYQND
. |||.||..|                       .  | |||   ||||.. .. ..                 |.|....|. .  ..| | |.. .. 
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY

A---------QFLADVR----NKTIK----------VNNTAEGNLGWLINRSLQFDPDNRPTAQSMLDYM
          .... |       .|.           ....   .  |. .  . ||..||..|  |...
MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 94466.m00030.AA TyrKc 16-264 22 1e-16 47.62 SMART 1-280 (280) Show / Hide 
Range on Protein: 16-264
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

YVLQEELGLGAFSTVFLAIHSKTGEKVAIKVIDRNTATETDMIVYVENELRIQSRL--NHPNIAKVYDVIYTP-------EIIAIVMEYMPNGDMQMLIN
 .| ..|| ||| .|.... .   ..||.|..  ..      .    .|.|| ..|  .|||| . | |. ..       | . |||||||.|| .  . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

NNFI-FKQSEQIRIAIELLDALNYLHEKGISHRDIKTANILFDKDMHPKLIDFGFSREFSAK------MKTYC-----GTHLL-----MAPEIISNKVYN
..   .. .. . ...   .  .|||.|.. |||. . |.| ... . |  ||| ||.   .       ..|      |.. .     |||| |  ....
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

GMKADIWAYGVTMHIMATHCYPFSYQ------NDAQFLADVRNK--TIKVNN-------TAEGNLGWLINRSLQFDPDNRPTAQSMLDYM
  | |.|..||.|  . | . .  .       .... ...|..     .  |       ..   .  .. .  ..||..||| .   ...
-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 94466.m00030.AA Pkinase_Tyr 16-162 28 1.3e-16 56.85 Pfam 1-159 (270) Show / Hide 
Range on Protein: 16-162
Range on HMM: 1-159/270
Sequence Identity: 28% (45 aa)

YVLQEELGLGAFSTVFLAIHS----KTGEKVAIKVIDRNTATETD-MIVYVENELRIQSRL-NHPNIAKVYDVIY-TPEI--IAIVMEYMPNGDM-QMLI
 .. ..|| ||| .|....      .|. .||.|.. ...|.. . ..    .|..| . | .|||| . | |..   |   | |||||||.||.   | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

NN---NFIFKQSEQIRIAIELLDALNYLHEKGISHRDIKTANILFDKDMHPKLIDFGFSR
..   .  .. .. . ....  ....||..|.. |||. . |.| ..... |  ||| .|
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR
Kinase 94466.m00030.AA Pkinase_Tyr 178-202 44 0.033481 8.08 Pfam 181-204 (270) Show / Hide 
Range on Protein: 178-202
Range on HMM: 181-204/270
Sequence Identity: 44% (11 aa)

MAPEIISNKVYNGMKADIWAYGVTM
|||| |......  | |.|..||.|
MAPECINYGKFT-TKSDVWSFGVLM
Kinase 94466.m00030.AA Pkinase_Tyr 248-264 29 6.63519 0.3 Pfam 254-270 (270) Show / Hide 
Range on Protein: 248-264
Range on HMM: 254-270/270
Sequence Identity: 29% (5 aa)

QFDPDNRPTAQSMLDYM
..||..||| .  .  .
HYDPEDRPTFSEIHEQL