Gene 89135.m00259 (T.vaginalis)

89135.m00259

Species: T.vaginalis
Alias: 89135.m00259, TvagK0852
External Links:
Annotation:

Classification

Group: Other
Family: Other-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
89135.m00259.AA Protein None 573 None Fasta, JSON
89135.m00259.kin_dom Protein Kinase Domain None 114 None Fasta, JSON

Protein domain

Protein domains of 89135.m00259.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

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Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 89135.m00259.AA AGC 215-296 21 3.3e-26 63.39 In-house 166-295 (395) Show / Hide 
Range on Protein: 215-296
Range on HMM: 166-295/395
Sequence Identity: 21% (31 aa)

IQALHA-KKILCRD-LKPDNILMDDDFNPVYVDFDVSEYNSL-----------------------------------------------------TAYDF
.. ||  ..| .|| |||.|||.|.| .   .||  .  .                                                       ... |
LEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTF

TG--TPFYMAPEVLRNRFREARYSQCGTESDIFS--LGCVI
 |  || |||||.|           .| . |. |  |||..
CGPCTPEYMAPEIL-----------YGKACDWWSFGLGCLM
Pkinase 89135.m00259.AA Pkinase 182-296 27 3.2e-20 72.57 Pfam 80-202 (293) Show / Hide 
Range on Protein: 182-296
Range on HMM: 80-202/293
Sequence Identity: 27% (36 aa)

PYYKNG----TLTKYLH--ENPDL--TNHELVELIQKISNMIQALHAKKILCRDLKPDNILMDDDFNP----VYVDFDVS----EYNSLTAYDFTGTPFY
.|  .|     |  |..  ..  .  . .|.   .  |   .. .|...|. |||||.|||.|.. ..       || ..    . |.  ...|.|||.|
EYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWY

MAPEVLRNRFREARYSQCGTESDIFSLGCVI
|||||.|       ..  |...|..|.||..
MAPEVIR------GGQYYGPKVDMWSCGCIL
Kinase 89135.m00259.AA Ciliate-E2 183-306 19 1.4e-18 60.36 In-house 115-296 (365) Show / Hide 
Range on Protein: 183-306
Range on HMM: 115-296/365
Sequence Identity: 19% (37 aa)

YYKNGTLTKYLHENPD-----------LTNHELVELIQKISN---------------MIQALHAKK-ILCRDLKPDNILMDDDFNPVYVDFDVSEYNS--
|.. |.| .|. .|.            .|  |  .....| .                .. || |. |. ||.||.|||.     .  .||  | ...  
YCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDD

--------------------------------LTAYDFTGTPFYMAPEVLRNRFRE--ARYSQCGTESDIFSLGCVINFIFNQNYPY
                                 ... . ||| |||||.|..   .      . ....||.|||... .    ..|.
NQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF
Kinase 89135.m00259.AA Ciliate-E2-Unclassified 183-306 22 1.8e-18 60.72 In-house 102-270 (352) Show / Hide 
Range on Protein: 183-306
Range on HMM: 102-270/352
Sequence Identity: 22% (39 aa)

YYKNGTLTKYLHENPD-----------------LTNHELV-----ELIQKISNMIQALHAKK-ILCRDLKPDNILMDDD---FNPVYVDFDVSEYNSLT-
| ..|.| .|. ...                  .|  . .      ..  | . .. || |. |. ||.||.|||.|..   ...   ||  | ..    
YCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNN

-----------------AYDFTGTPFYM----APEVLRNRFREARYSQCGTESDIFSLGCVINFIFNQNYPY
                 ...|.||| ||    |||||..   . . .    ..||.|||... ..  ..||.
NCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA---YKCDIWSLGVILYEMLFGYYPF
Kinase 89135.m00259.AA STE 218-312 28 1.1e-17 59.14 In-house 168-274 (359) Show / Hide 
Range on Protein: 218-312
Range on HMM: 168-274/359
Sequence Identity: 28% (33 aa)

LHAKKILCRDLKPDNILMDDDFNPVYVDFDVSEYNSL-------------------TAYDFTGTPFYMAPEVLRNRFREARYSQCGTESDIFSLGCVINF
|| ..|  ||.||.|||.        .|| |.   .                      . |.||| .|||||.... .  | ....| .|| ||||.|  
LHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLGCTIIE

IFNQNYPYTNLTPL
  . ..|. ...|.
MATGKPPWHDMHPM
Kinase 89135.m00259.AA Ciliate-E2a 183-296 24 3.7e-16 44.08 In-house 80-206 (275) Show / Hide 
Range on Protein: 183-296
Range on HMM: 80-206/275
Sequence Identity: 24% (32 aa)

YYKNGTLTKYLHENPDLTNH--ELVELIQKIS-NMIQALHAKKILCRDLKPDNILMD-------DDFNPVYVDFDVSEYN--SLT--AYDFTGTPFYMAP
|.. |.| ... .. ...    |  ...|..    .. .| ..|. |||||.|||..       .... . .||  ...         .   ||| |.||
YCEGGELYDKIKQCKRFFEEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAP

EVLRNRF--REARYSQCGTESDIFSLGCVI
||| |.      .|.   |  |..|.|...
EVLNNKEVLKHKQYD---TKCDMWSCGVIF
Kinase 89135.m00259.AA TKL 183-296 23 4.7e-16 54.31 In-house 119-279 (364) Show / Hide 
Range on Protein: 183-296
Range on HMM: 119-279/364
Sequence Identity: 23% (39 aa)

YYKNGTLTKYLHENPDLTNHELVELIQKISNMIQALHA--------KKILCRDLKPDNILMDDDFN--------------PVYVDFDVSEYNSL------
|...|.|  |||       | .. ... |.  .. ||.        ..|. ||||..||| |....              .   ||  |  .|       
YCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMND

----------------TAYDFTGTPFYMAPEVLRNR--FREA-------RYSQCGTESDIFSLGCVI
                | .   ||| .|||||||.   ..|.       . ..  . .|..| | |.
TMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVL
S_TKc 89135.m00259.AA S_TKc 119-349 21 2.7e-14 32.78 SMART 1-231 (231) Show / Hide 
Range on Protein: 119-349
Range on HMM: 1-231/231
Sequence Identity: 21% (55 aa)

LESYEAIGYGAHSVVIHSKTIT--PDLVFKYSKLGNQTENEIK----NHIGMETYSPGLQIPSKYFTSSPYYKN--GTLTKYLHENPD------LTNHEL
 |  . || || ..|   . .        |  |  .....||.    .|    ..    |  ....    |  .  |.| .|.....       ..  . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKKHHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HA

VELIQKISNMIQALHAKKILCRDLKPDNILMDDDFNPVYVDFDVSEYNSLTAYDFTGTPFYMAPEVLRNRFREARYSQCGT-ESDIFSLGCVINFIFNQN
  ... | . .. .| ..|. |||||.|||.|.  .    || ..       . | |||.|||||||          . |. ..|. |.||..   .   
RFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL----------GYGKCKCDWWSCGCILYEMLCGY

YPYTNLTPLI------HPDIRKLILEMTHTDAKKRPSIFDVIAECQKI--EESF
 |.   ..         |. . .|  . . | .|||.. .. .....|   . |
PPFP--QMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 89135.m00259.AA CAMK 218-295 23 5.5e-13 37.48 In-house 195-323 (425) Show / Hide 
Range on Protein: 218-295
Range on HMM: 195-323/425
Sequence Identity: 23% (30 aa)

LHAKKILCRDLKPDNILMDDD-----------------FNPVYVDFDVS-EYNSL-------------------------TAYDFTGTPFYMA-PEVLRN
.| ..|  |||||.|||.||.                 .|   .||  . ....                            ..| ||| ||| ||||. 
CHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNG

RFREARYSQ--------CGTESDIFSLGCV
  . . . .        .| ..|. |.|..
KGHCNMQ-NATDEEKPYYGPKCDMWSCGVI
Kinase 89135.m00259.AA Dicty3 194-296 19 2.5e-12 36.79 In-house 103-287 (351) Show / Hide 
Range on Protein: 194-296
Range on HMM: 103-287/351
Sequence Identity: 19% (38 aa)

HENPDLTNHELVELIQKISNMIQALHAK-KILCRDLKPDNILMDDDF---NPVY-----------------------VDFDVS---EYNS----------
|.|  . .||....| ..   .  .| . .|. ||.|.|||. |.|    . .                         ||. |   .|.|          
HKNNRFNEHEISKIICDLVKTLNYIHKNCHIIHRDIKCDNIMLDNDEQHQCNNNNNKMSSTCRDIQCYYSNEINWKLIDFGLSKNISYYSNNNNNNNYNN

-----------------------------------------------LTAYDFTGTPFYMAPEVLRNRFREARYSQCG--TESDIFSLGCVI
                                               .  | ..||  |||||...|       .||.    |||.||||..
NNNNNNNNNNNNNNNNNNNNNNNNNNNNTNNNVKIINNNIYSNKQYKQKCYSICGTIHYMAPEIKLN-------NQCCACRKSDIWSLGCTV
Kinase 89135.m00259.AA STE-Unique 218-321 20 3e-12 39.28 In-house 419-569 (616) Show / Hide 
Range on Protein: 218-321
Range on HMM: 419-569/616
Sequence Identity: 20% (31 aa)

LHAKK--ILCRDLKPDNILMDDDF-----NPVYVDFDVSEYNSLT-----------------------------------------AYDFTGTPFYMAPE
|| ..  |. |||||.||. . |      . . .||. .   ..                                            .  |||.||.||
LHSQHNPIIHRDLKPHNIFCMQDGKGRVCKVKICDFGHATCCQPDHFEKDNNSKNSNTWININNNSSTNSTAQQTPMWDLNINNYTMKYCCGTPCYMCPE

VLRNRFREARYSQCGTESDIFSLGCVINFIFNQNYPYTNLTPLIH-PDIRKLI
|.. |  .   . ..| .||.||||..  . ..  |........  .... .|
VINCR--NQINNPYDTKVDIWSLGCMCFHMCCGCPPWHQRYHMQAYIEMCIHI
Kinase 89135.m00259.AA Ciliate-E2b 215-307 27 3.1e-12 33.64 In-house 115-211 (272) Show / Hide 
Range on Protein: 215-307
Range on HMM: 115-211/272
Sequence Identity: 27% (27 aa)

IQALHAKKILCRDLKPDNILMDDDFNPVYVDFDVSEYNSLTAY----DFT--GTPFYMAPEVLR-NRFREARYSQCGTESDIFSLGCVINFIFNQNYPYT
.. || ..|. ||.|| ||. | .  .  .|. .. . .  .      ||  |||.|||||..   .     |   ....||.|.| .  ..     |..
LEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSLQPGGKGY---TYKVDIWSVGICLYEFMCGYVPWA
TyrKc 89135.m00259.AA TyrKc 119-345 15 5e-06 -124.88 SMART 1-280 (280) Show / Hide 
Range on Protein: 119-345
Range on HMM: 1-280/280
Sequence Identity: 15% (47 aa)

LESYEAIGYGAHSVVIHSKTITPDLVF-KYSKLGNQTENEIKNHIG-METY---------SPGLQIP--------SKYFTSSPYYKNGTLTKYLHENPD-
..  . .| ||  .| . . .    |  |  | .   . .. . .  |  .           |  .           ..    | ..| | .||... . 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

LTNHELVELIQKISNMIQALHAKKILCRDLKPDNILMDDDFNPVYV---DFDVSEYNSLT-------AYDFT----GTP-----FYMAPEVLRNRFREAR
|.. .|..    |..  . || |..  |||   |.| ....    |   ||  | .            |  .    |.        ||||..       .
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-------N

YSQCGTESDIFSLGCVI----NFIFNQNYP------------------YTNLTPLI---------HPDIRKLILEMTHTDAKKRPSIFDVIAECQKI
|. . |.||..| | ..     .     .                   |    |           .... .....  | |...||.  ..   ....
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI---HECF
Kinase 89135.m00259.AA TKL 315-334 40 0.054509 2.97 In-house 337-356 (364) Show / Hide 
Range on Protein: 315-334
Range on HMM: 337-356/364
Sequence Identity: 40% (8 aa)

PDIRKLILEMTHTDAKKRPS
|...||. .  ..|..||||
PSMKKLMQDCWDHDPEKRPS