Gene 91117.m00135 (T.vaginalis)

91117.m00135

Species: T.vaginalis
Alias: 91117.m00135, TvagK0088
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
91117.m00135.AA Protein None 371 None Fasta, JSON
91117.m00135.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 91117.m00135.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 91117.m00135.AA S_TKc 15-266 29 2.6e-81 277.37 SMART 1-231 (231) Show / Hide 
Range on Protein: 15-266
Range on HMM: 1-231/231
Sequence Identity: 29% (80 aa)

YYLEEIVGQGNTCVVVKARDIH-DNVFACKIISKLKFSSATNIKHFQDELAVMRTLSHPNIINLVEILQDSNNVYIFEEYCEL--GDLTREILRSKC---
| . ...|.|   .| |.|... . ..|.|||.          .|.. |.....   ||||..| .. || ...|.. |||.   ||| . | . ..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---IEEDRAGSIMTQVFKGLSFMHQHHIAHRDIKPENIFVCSNGLIKVADFGYSTLNSGTDYRSTVCGTLIYIAPEILKQTPYNALIADAWSCGVLLYAM
   . | .| ..| |....| ..|.|.| |||.|||||....   ||..||| ...       .|.|||. |.|||.|   .|.   .| ||||..|| |
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

VCGYLPWEKKSQAGMTEEIKFKKIEYPETMSPECRYLIEHLCDRNVDTRFSIAQAME-------CDFI
.||| |..       ...  ||||      |||.. .|....... . | .. .|..         ..
LCGYPPFP-------QMQMMFKKIG-----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 91117.m00135.AA CAMK 20-266 20 1.5e-79 255.83 In-house 1-425 (425) Show / Hide 
Range on Protein: 20-266
Range on HMM: 1-425/425
Sequence Identity: 20% (88 aa)

IVGQGNTCVVVKARDIHDNV-------------FACKIISK----------------LKFS---------SATNIKHFQDELAVMRTLS-------HPNI
. |.|. ..| ........              .|.|||.|                ...|         .. . | .. |...|..|.       ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

INLVEILQDSNN-------------------VYIFE---EYCELG----DLTREILRSKC---------------IEEDRAGSIMTQVFKGLSFMHQHHI
|.| |. .|...                   .|..    |||. |    ||   | . .|               ..|. |  .. |.  .. ..|.|.|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHRDIKPENIFVCSN-----------------GLIKVADFGYST-LNSG-----------------------TDYRSTVCGTLIYIA-PEILKQ------
.|||.||||| ...|                 . ||..||| .. ...|                       ..  .|.|||. |.| ||.|..      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------TPYNALIADAWSCGVLLYAMVCGYLPWEKK-------------SQAGMTEEIKFKKIE-YPETMSP-----------------------ECRY
        ||    .| |||||.||.|.|||.|.. .             ..  . | |.  | . .|. .||                       ||. 
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LIEHLCDRNVDTRFSIAQAMECDFI
|| ..  .. . |..|.|...  ..
LIRKMLQVDPEKRMTIEQCLNHPWM
Pkinase 91117.m00135.AA Pkinase 15-266 27 2.5e-73 254.7 Pfam 1-293 (293) Show / Hide 
Range on Protein: 15-266
Range on HMM: 1-293/293
Sequence Identity: 27% (81 aa)

YYLEEIVGQGNTCVVVKARDIHDNV-FACKIISKLKFSSATNIKHFQ-DELAVMRTLSHPNIINLVEILQDSNNVYIFEEYCELG----DLTREILR---
| .....|.|.  .| |.... ..  .|.|||.| . .|  .. |.   |...|. |.||||. | .. .|....|.  |||| |    ||  ....   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLF-DYISTWR

SKCI--EEDRAGSIMTQVFKGLSFMHQHHIAHRDIKPENIFVCSNGLI----KVADFGYSTL--NSGTDYRSTVCGTLIYIAPEILK-QTPYNALIADAW
..|.  .|. . ..|.|...|| ..|.. | |||.|||||.. .|| |    |..||| . .  .      .|.|||. |.|||... ...|   . | |
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV-DMW

SCGVLLYAMVCGYLPWEKK------SQAGMTEEIKFKKIEYPET---------------------MSPECRYLIEHLCDRNVDTRFSIAQAMECDFI
|||..|| |.||..|.  .      .|  | ..|. .......                      .|.||. .|. .....   | ...|... ...
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 91117.m00135.AA CAMKL 15-266 30 1.5e-68 217.86 In-house 1-297 (297) Show / Hide 
Range on Protein: 15-266
Range on HMM: 1-297/297
Sequence Identity: 30% (91 aa)

YYLEEIVGQGNTCVVVKARD-IH-DNVFACKIISKLKFSSATNIKHF------------QDELAVMRTLS---HPNIINLVEILQDSNN------VYIFE
| ...  |.|.  .|  |.. ..     | ||| | | .  ...|              . | . |. |.   ||||| | |.......      .|.. 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCELGD--LTREILRSKC----IEEDRAGSIMTQVFKGLSFMHQHHIAHRDIKPENIFVCSNG--LIKVADFGYSTLNS-G----TDYRSTVCGTLIYI
|||. |.  |   | . ..    ..|. |  . .|.  .....|.|.|.||||||||| . .||   ||..||| |..   .     .  .| ||.. | 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEILKQ--TPYNALIADAWSCGVLLYAMVCGYLPWE-------KKSQAGMTEEIKFKKIEYPE---TMSPECRYLIEHLCDRNVDTRFSIAQAMECDFI
||||..   .||..  .| |||||.||||||||||..       .|.     .... .  .||     .| .|| || ..  .| . |..| | |.  . 
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 91117.m00135.AA Ciliate-E2 15-266 23 2.5e-65 223.21 In-house 1-365 (365) Show / Hide 
Range on Protein: 15-266
Range on HMM: 1-365/365
Sequence Identity: 23% (89 aa)

YYLEEIVGQGNTCVVVKARDIHDNV------------------------FACKIISKLKFSSATNIKHFQ----------DELAVMRTLSHPNIINLVEI
| . .. ||||  .| |.... ..                         .| ||..| .  .  ...|             |. ....|.|||||...| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

LQ--DSNNVYIFEEYCELGDLTR-----EILRSKCIE------EDRAGSIMTQVFK---------------GLSFMHQHH-IAHRDIKPENIFVCSNGLI
 |  | ||.|.  |||. |||        . | ..||      |  .. ||.|...               .| ..|. . | |||||||||..     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KVADFGYSTLNSGTDYRST--------------------------------VCGTLIYIAPEILKQTPYNA--------LIADAWSCGVLLYAMVCGYLP
|..|||.|. ..   .. |                                .|||. | |||||.  .|.           .| ||.||.|| |..|..|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

WEKKSQAGMTEEIKFKKIEYP------------------ETMSPECRYLIEH----LCDRNVDTRFS-IAQAMECDFI
.         ..|| .||..|                  .  |.||  ||      . ... . |.. . |...  ..
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 91117.m00135.AA AGC 15-266 18 9.6e-64 162.7 In-house 1-395 (395) Show / Hide 
Range on Protein: 15-266
Range on HMM: 1-395/395
Sequence Identity: 18% (73 aa)

YYLEEIVGQGNTCVVVKARDIH-------DNVFACKIISKLK--------FSSATNIKH-------FQDELAVMRTLS----------HPNIIN-LVEIL
. .  ..|.|    |  .|. .       . ..|.|...| .            |.. |       .. |  .. ...          ||.|.. |    
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDSNN--VYIFEEYCE--------LGD-LTREIL----RSKCIEEDRAGSIMTQ-------VFKGLSFMHQ-HHIAHRD-IKPENIFVCSNGLIKVADFG
|| ..  .|.  ||..         |.  .  .|    .... .|.||  .. .       .  .| ..|. ..| ||| .|||||   ..| || .|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

YSTLNS---------------------------------------------------GTDYRSTVCG--TLIYIAPEILKQTPYNALIADAWS--CGVLL
 .. .                                                    ..|  .| ||  |  |.|||||         .| ||   |.|.
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCLM

YAMVCGYLPWEKKS----------QAGMTEEIK------FKKIEYP----------ETMSPECRYLIEHLCDRNVDTRFS----------IAQAMECDFI
| |..|| |   ..          .. | . |.      ..|...|          . .|||.. ||..|. .. . |            . . ..  . 
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 91117.m00135.AA MARK 15-266 33 4.4e-62 201.77 In-house 1-262 (262) Show / Hide 
Range on Protein: 15-266
Range on HMM: 1-262/262
Sequence Identity: 33% (88 aa)

YYLEEIVGQGNTCVVVKARDIH-DNVFACKIISKLKFSSATNIKHFQDELAVMRTLSHPNIINLVEILQ--DSNN-VYIFEEYCELGDLTREILRS--KC
| .    |.|. ..| .|...| .  .| ||. | | .   ..| .. |...|. |.||||| | .. .  .... .|.  ||.. |.|   |      .
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

IEEDRAGSIMTQVFKGLSFMHQHHIAHRDIKPENIFVCSNG--LIKVADFGYSTLNSGTDYRSTVCGTLIYIAPEILKQTPYNALIADAWSCGVLLYAMV
..|. |  | .|.  .....|...|.||||||||| . .||   || .|||.|.        .| |||. | ||||... ||..  .| ||.||.||.||
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

CGYLPWEKKS--QAGMTEEIKFKKIEYPETMSPECRYLIEHLCDRNVDTRFSIAQAMECDFI
|||.|.. ..  .  . ..|   | ..|  .|.||| ||  |   | . | .| . |.  ..
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 91117.m00135.AA ULK 15-266 26 7.1e-59 201.92 In-house 1-329 (329) Show / Hide 
Range on Protein: 15-266
Range on HMM: 1-329/329
Sequence Identity: 26% (89 aa)

YYLEEIVGQGNTCVVVKARDIHDN-----VFACKIISKLKFSSATN-------IKHFQDELAVMRTLS--------HPNIINLVEILQDS--NNVYIFEE
|.| .. |.|   .| |.|.. ..     ..|||.|.| |..   |       .. .. |  .|..|         ||||. | .....|  ||.||. |
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCELGDLTREIL----------RSKCIEEDRAGSIMTQVFKGLSFMHQHHIAHRDIKPENIFVCSN------------GLIKVADFGYSTLNSGT-----
||. |||   |           . | ..|. | ... |   |. ..|.| | ||||||.|| .  .            | .|.|||| .   .       
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

DYRSTV-----CGTLIYIAPEILK----QTPYNALIADAWSCGVLLYAMVCGYLP---WEKKSQA--GMTEE----------IKFKKIEYP-----ETMS
.. ..|     ||| .| ||.||.    | ||.   .| || |...| |. |. |   | . .|   .....          || .....|      . |
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

PECRYLIEHLCDRNVDTRFSIAQAMECDFI
|||. ||  .  .. . |.|. .  .  ..
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 91117.m00135.AA ULK 15-266 27 1.5e-58 200.86 In-house 1-324 (324) Show / Hide 
Range on Protein: 15-266
Range on HMM: 1-324/324
Sequence Identity: 27% (89 aa)

YYLEEIVGQGNTC-VVVKARDIHD----NVFACKIISKLKFSSATN-------IKHFQDELAVMRTLS---HPN--IINLVEILQDS--NNVYIFEEYCE
|.| .. |.|    .| |.|.. .     ..|||.|.| |..   |       .. .. |  .|..|    |||  |. | .....|  ||.||. |||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

LGDLTREIL---------RSKCIEEDRAGSIMTQVFKGLSFMHQHHIAHRDIKPENIFVCSN------------GLIKVADFGYSTL-NSGT---DYRST
 |||   |          . | ..|. | ... |   |. ..|.| | ||||||.|| .  .            | .|.|||| .   ....   . . |
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

VC------GTLIYIAPEILK----QTPYNALIADAWSCGVLLYAMVCGYLP---WEKKSQAG-MTEE----------IKFKKIEYP-----ETMSPECRY
 .      || .| ||.||.    | ||.   .| || |...| |. |. |   | . .|   . ..          || ..|..|        ||||. 
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LIEHLCDRNVDTRFSIAQAMECDFI
||  .  .. . |.|. .  .  ..
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 91117.m00135.AA CAMK-Unique 15-266 20 2.6e-55 180.97 In-house 1-363 (363) Show / Hide 
Range on Protein: 15-266
Range on HMM: 1-363/363
Sequence Identity: 20% (76 aa)

YYLEEIVGQGNTCVVVKARDIHDNV-FACKIISKLKFSSATNIK-----------------HFQDELAVMRTLSHPNIINLVEI----LQDSN-------
| . .|.|.|| ..| .. |..  . .|||.. | . ..  ..                   .  |........||||| |...     .|..       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------NVYIFEEYCELGDLTREILR--------------------SKCIEE--DRAGSIMTQVFKGLSFMHQHHIAHRDIKPENIFVCSNGL-----
        . ||. |||. |||  .|..                        .|    . .||...   ...||.  | |||.|.||| ||...      
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

-----------IKVADFGYSTLNSGTDYRS---TVCGTLIYIAP--------------EILKQTPYNALIA---DAWSCGVLLYAMVCGYLPWEKKSQA-
           ||..||| ... ..   ..   |.|||..|.||              |.... .|        | ||.||..| | ||..| .  . . 
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------GMTEEIKFKKI-EYPE-----T--MSPECRYLIEHLCDRNVDTRFSIAQAMECDFI
       .  | |.  .. ....     .  .|.|   ... .  . .| | |.... | ..|
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase 91117.m00135.AA Ciliate-E2-Unclassified 15-266 23 7.3e-55 188.59 In-house 1-352 (352) Show / Hide 
Range on Protein: 15-266
Range on HMM: 1-352/352
Sequence Identity: 23% (82 aa)

YYLEEIVGQGNTCVVVKARDIHDNVF-----ACKIISKL-KFSSATNIKHFQDELAVM------------------RTLSHPNIINLVEILQDSNNVYIF
| . .. |||. ..| |.... .. .     ..||...  |     .  . . .....                  . . ||.|...... || .|.|| 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

EEYCELGDLTREILRS------------------KCIEEDRAG-----SIMTQVFKGLSFMHQHH-IAHRDIKPENIFVCSNG---LIKVADFGYSTLNS
 |||| ||| ......                  |...|  |       .. |. .||...|. . | |||||||||.. .||    ||..||| |  . 
MEYCEGGDL-WQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

----------------GTDYRSTVCGTLIYI----APEILKQTPYNA---LIADAWSCGVLLYAMVCGYLPWEKKSQAG----------------MTEEI
                  .  .|.|||..|.    |||.|..  |.      .| ||.||.||.|. ||.| . ...                  . ..|
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

KFKKIEYPE--------TMSPECRYLIE----HLCDRNVDTRFSIAQAMECDFI
| |.|..|.        . |||.  .|.     . . | . | .. |...  ..
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 91117.m00135.AA STE 15-266 19 5.8e-49 168.99 In-house 1-359 (359) Show / Hide 
Range on Protein: 15-266
Range on HMM: 1-359/359
Sequence Identity: 19% (71 aa)

YYLEEIVGQGNTCVVVKARDIH----------------DNVFACKIISKLKFSS--------------ATNIKHFQDELAVMRTLS--HPNIINLVEILQ
. . |..|.|.. .|.||....                 ...| |.... . ..               .... .. |. .|. ..  ||||..      
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DS-------NNVYIFEEYCELGDLTREIL-RSKC-------------IEEDRAGSIMTQVFKG-LSFMHQHHIAHRDIKPENIFVCSNGLIKVADFGYST
.        ....|. ||.. | |.  |  . .|             ..|.  . |  |. || |.. |.||| |||||| ||..     .| .||| ..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

LNSG----------------TD-YRSTVCGTLIYIAPEILKQ------TPYNALIADAWSCGVLLYAMVCGYLPWEKKSQAGMTEEIKFK----------
  .                 ..  | |..||  . |||...|       .|..  .| || | ..  |..|  || . .   .  .| |.          
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTK-CDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

--------KIEY-----------------PETMSPECRYLIEHLCDRNVDTRFSIAQAME--CDFI
        ...                  |. .|||..  |.. .... . | .  | ..    ||
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 91117.m00135.AA TyrKc 15-266 19 8.9e-14 0.03 SMART 1-280 (280) Show / Hide 
Range on Protein: 15-266
Range on HMM: 1-280/280
Sequence Identity: 19% (57 aa)

YYLEEIVGQGNTCVVVKARDIHDNVFACKIISKLKFSSATNIKHFQDELAVMRTL--SHPNIINLVEILQDS-------NNVYIFEEYCELGDLTREILR
  |... | |. ..|.|.. .     | | . . .      .. | .|. .|. |  .||||..|. .  ..         ..|  ||...|||   . .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

SKC-IEEDRAGSIMTQVFKGLSFMHQHHIAHRDIKPENIFVCSNGLIKVADFGYSTLNSGT--------DYRSTV--CGT--LIY--IAPEILKQTPYNA
..  .  .   |...|. .| .. |.... |||.   |. | .|. .|..||| |               ||..   .|   | .   ||| ..   .. 
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

LIADAWSCGVLLY-AMVCGYLPWEK-----KSQAGMTEEIKFK-KIEYPET--------MSPECRYLIEHLCDRNVDTRFSIAQAMECDFI
   | || ||...  .  |  |..      .| . . | .|     . |.         ...|   ...  .... . | . ..   ....
K-SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 91117.m00135.AA Pkinase_Tyr 59-157 28 5.5e-12 41.23 Pfam 50-156 (270) Show / Hide 
Range on Protein: 59-157
Range on HMM: 50-156/270
Sequence Identity: 28% (31 aa)

FQDELAVMRTL-SHPNIINLVEILQ-DSNN--VYIFEEYCELGDLTREILRSK-----CIEEDRAGSIMTQVFKGLSFMHQHHIAHRDIKPENIFVCSNG
|  |...|..| .||||..|. .   ..    .||  ||...||| .. ||..      .   .  .. .|. ||... ..... |||.   |. | .|.
FMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL-LDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENN

LIKVADFG
 .|..|||
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