Gene GL50803_11178 (G.lamblia)

GL50803_11178

Species: G.lamblia
Alias: GK012, GL50803_11178
External Links: GiardiaDB ,
Annotation:

Classification

Group: CAMK
Family: CAMK1

Sequence

Name Sequence Type Origin Length Description Download
GL50803_11178.AA Protein None 335 None Fasta, JSON
GL50803_11178.kin_dom Protein Kinase Domain None 275 None Fasta, JSON

Protein domain

Protein domains of GL50803_11178.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_11178.AA CAMK 13-284 19 1.1e-65 210.38 In-house 1-425 (425) Show / Hide 
Range on Protein: 13-284
Range on HMM: 1-425/425
Sequence Identity: 19% (87 aa)

KIGESAVGMVYYGTEIRTN------------TPVAIKLICKASTKL---------------------------DPYFMEREANTLLS-------ITHENI
..|. . | |. .....|.            . |||| | |   |                            |  ...|| . . .       . |.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

NRVRGIYESAEN-------------------LYIVM---DLCVGN----DVFTHAIRK---------------KYYSEDDAREIIRQICRALAYLHSRHI
 .   .||....                   .|.||   ..| |     |.| . ...               ....|..|| ..|||| |..|.||..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHLGIKPENLLITCNS--QRPIVSHLNDSEGPQPSRELDE-----KYLVKLVDVMLSQYLHGGEPLI-------------------------RPEYISFM
.|. .||||.|.. |.  . | |   .|           |     .. .|..|  ..... .|| .                          .    ..|
VHRDLKPENILLDDNNDDSDP-V-E-HD-----------EIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYM

A-PEVLRH--------------QPYSTEPDIYAMGVTTYLLLGGVLPYEER-------------DAGELLVLIEKGQWGFQNANFNGISAN---------
| ||||.               ..|. . |. ..|| .| .| | .|...              .  ||.  | ||.. |    | .||.|         
AAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDI

-----------AKDFITQCLKPAISERITARKALQHPWL
           .||.| ..|..  ..|.|.  .|.|||.
SDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase GL50803_11178.AA Ciliate-E2 8-284 18 2.5e-54 184.9 In-house 1-365 (365) Show / Hide 
Range on Protein: 8-284
Range on HMM: 1-365/365
Sequence Identity: 18% (74 aa)

DISYHKIGESAVGMVYYGTEIRTNT------------------PVAIKLICKASTKLDPYFMEREANTLL-----------------SITHENINRVRGI
 .   |||. . | ||... ....                    |.||.. . . | .  ..    . ..                 .. | || .    
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YE--SAENLYIVMDLCVGNDVFTHAI--RKK---------YYSEDDAREIIRQICR---------------ALAYLHSRH-IAHLGIKPENLLITCNSQR
..  . .|.|.||..| |.| | . .  .||         |..|  ...|..||..               || ||||.. | |  |||||.|.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

PIVSHLNDSEGPQPSRELDEKYLVKLVDVMLSQYLH--------GGEPLIRPEYI--------------------------SFMAPEVLRHQP-------
                       .|..|  ||....        . .  . ..                             .||||.|. ..       
-----------------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQ

--YSTEPDIYAMGVTTYLLLGGVLPYEERDAGELLVLIEKGQWGFQNA--------------NFNGISANAKDFITQ----CLKPAISERIT-ARKALQH
  |... ||...||. | .| | .|.        .  |..... |...              ... .| ..||.| .    .|.   ..||| . ..|.|
KGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNH

PWL
||.
PWF
Kinase GL50803_11178.AA S_TKc 8-284 27 2.4e-47 164.53 SMART 1-231 (231) Show / Hide 
Range on Protein: 8-284
Range on HMM: 1-231/231
Sequence Identity: 27% (80 aa)

DISYHKIGESAVGMVYYGTEIRTNTPVAIKLICKASTKLDPYFMEREANTLLSITHENINRVRGIYESAENLYIVMDLCVG--NDVFTHAIRKKY-----
     |||. | | || .....|.  |||| |           ..|| . | .  |.|| .  ..... ..||.||..| |   |.|..  ....     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-YSEDDAREIIRQICRALAYLHSRHIAHLGIKPENLLITCNSQRPIVSHLNDSEGPQPSRELDEKYLVKLVDVMLSQYLHGGEPLIRPEYIS---FMAPE
 ..| .|| ...|||.||.|.||..| |  .||||.|..                            .|. |  |.  |          ..    .||||
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--------------------------HIKICDFGLARQL--------TTFCGTPWYMAPE

VLRHQPYST-EPDIYAMGVTTYLLLGGVLPYEERDAGELLVLIEKGQWGFQNANFNGISANAKDFITQCLKPAISERITARKALQ-------HPWL
||   .|.. . |... |.. | .| |  |..     .. ....|             |  ||||| .||.   ..|.|| .|||       |||.
VL---GYGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase GL50803_11178.AA Ciliate-E2-Unclassified 7-284 21 2.6e-45 155.11 In-house 1-352 (352) Show / Hide 
Range on Protein: 7-284
Range on HMM: 1-352/352
Sequence Identity: 21% (81 aa)

YDISYHKIGESAVGMVYYGTEIRTNTPVAIKLICKASTKLDPYFME-----REANTLLS-----------------ITHENINRVRGIYE--SAENLYIV
| |  ..||. . | ||   .. ..   |.| ..|.  . . . |.     .|.... .                 . | ....|. .|.  . .|.|||
YKI-IKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MDLCV-----------------GNDVFTHAIRKKYYSEDDAR-----EIIRQICRALAYLHSRH-IAHLGIKPENLLITCNSQRPIVSHLNDSEGPQPSR
|..|                  ||| | .  ..|  .|  |.      ...||. .| |||. . | |  |||||.|.. | .                 
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK-----------------

ELDEKYLVKLVDVMLSQ--------YLHGG--------EPLIRPEY--ISFM----APEVLRHQPYS----TEPDIYAMGVTTYLLLGGVLPYEERDAGE
    .| .|. |  .|         . . .        . ..      ...|    |||||. | |.     . ||...||  | .| | .|.. ..  .
----NYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQ

----------------LLVLIEKGQWGFQNANF----NGISANAKDFIT----QCLKPAISERITARKALQHPWL
                |.  | .... |.....     ..| .|||||.    ..||  ...|||. ..|.|||.
HQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase GL50803_11178.AA Ciliate-E2a 7-284 25 3.3e-43 125.04 In-house 1-275 (275) Show / Hide 
Range on Protein: 7-284
Range on HMM: 1-275/275
Sequence Identity: 25% (76 aa)

YDISYHKIGESAVGMVYYGTEIRTNTP-VAIKLICKASTKLDPYF-MEREANTLLSITHENINRVRGIYESAENLYIVMDLCVGNDVFTHAIRKKY-YSE
|..   |||. . | ||. . ..|.   ...|.| |.. . .... ...| | . .. | || .  ..||.  |.|.||..| | . . . |...  . |
YKF-IKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELY-DKIKQCKRFFE

D--DAREIIRQIC-RALAYLHSRHIAHLGIKPENLLIT-CNSQRPIVSHLNDSEGPQPSRELDEKYLVKLVDVMLSQYLHGGEP-LIRPEY--ISFMA--
   ....|..|.   .|.|.|.|.| |  .||||.|.. |... .                  ..  .|..|  |... .. |.  . . .    ..|  
EIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSI------------------QNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPE

----PEVLRHQPYSTEPDIYAMGVTTYLLLGGVLPYEERDAGELLVLIEKGQWGFQNAN-FNGISANAKDFITQCLKPAISERITARKALQHPWL
    .||| |. |.|  |.   ||  |.|| | .|.. ... | | ...| .  |.  . .. .| ..||.. . |..  ..||||  ||.||| 
VLNNKEVLKHKQYDTKCDMWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase GL50803_11178.AA CAMK1 7-136 35 1.2e-30 86.26 In-house 1-140 (276) Show / Hide 
Range on Protein: 7-136
Range on HMM: 1-140/276
Sequence Identity: 35% (50 aa)

YDISYHKIGESAVGMVYYGTEIRT---NTPVAIKLIC-KASTKLDP----YFMEREANTLLS---ITHENINRVRGIYESAENLYIVMDLCVGNDVFTHA
| .   .||. | . || .|...|   . ..||| |  | ..| .     . .|.| . . .   | |.||     .||| . .|.||.|. | . |   
YEFG-KEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRI

IRKKYYSEDDAREIIRQICRALAYLHSRHIAHLGIKPENLL
. |..|.|.|||.|..||. |. |.||. |.|  .||||||
VEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLL
Kinase GL50803_11178.AA CAMKL 7-140 29 1.7e-29 91.14 In-house 1-163 (297) Show / Hide 
Range on Protein: 7-140
Range on HMM: 1-163/297
Sequence Identity: 29% (49 aa)

YDISYHKIGESAVGMVYYGTEIRT-NTPVAIKLICKASTKLDPYFM--------------EREANTLLSIT---HENINRVRGIYESAEN------LYIV
|.|    .|. . | |  .| ||| .. |||| | |  ...||. .              .||.. . ..    |.|| .   ..|  |.      .|.|
YRIGK-TLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

MDLCVGND--VFTHAIRKKY----YSEDDAREIIRQICRALAYLHSRHIAHLGIKPENLLITCN
| .| | .   | . .....     .|..|| . |||. |..|.||..|.|  |||||.|...|
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDEN
Kinase GL50803_11178.AA CAMK-Unique 190-284 26 1.6e-25 81.03 In-house 239-363 (363) Show / Hide 
Range on Protein: 190-284
Range on HMM: 239-363/363
Sequence Identity: 26% (33 aa)

ISFMAP--------------EVLRHQPYSTEP----DIYAMGVTTYLLLGGVLPYEERDAG--------ELLVLIEKGQW-GFQNANFNG---ISANAKD
...|||              ||.  |.|.       || ..||..|..| | .| .. .          |..  | ||.   | .  ..|   || .|||
PCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKD

FITQCLKPAISERITARKALQHPWL
|...|..   . |..|  .|.|.|.
FVKCCMTVDPDHRWSAKELLEHQWI
Kinase GL50803_11178.AA Pkinase 9-137 30 5.4e-25 89.45 Pfam 2-141 (293) Show / Hide 
Range on Protein: 9-137
Range on HMM: 2-141/293
Sequence Identity: 30% (43 aa)

ISYHKIGESAVGMVYYGTEIRTNTPVAIKLICKASTKLDPYFME----REANTLLSITHENINRVRGIYESAENLYIVMDLCVGN----DVFTHAIR---
    |||. . | || .... |.  ||.| |.|  .. .   ..    .|.  .... |.|| | ....|.  ..|.||..| |     | | . |.   
HIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLF-DYISTWR

KKYY--SEDDAREIIRQICRALAYLHSRHIAHLGIKPENLLI
.. .  ||.... ...||.|.|.|.||. | |  .||||.||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILI
Kinase GL50803_11178.AA CAMK1 190-284 35 2.8e-24 67.44 In-house 177-276 (276) Show / Hide 
Range on Protein: 190-284
Range on HMM: 177-276/276
Sequence Identity: 35% (35 aa)

ISFMAPEVLRH---QPYSTEPDIYAMGVTTYLLLGGVLPYEERD-AGELLVLIEKGQWGFQNANFNGISAN-AKDFITQCLKPAISERITARKALQHPWL
....|||||     .||. . |.   || || || |  |  . .   ||. .| |....| .  .. ||   |||||.. |..  ..|.|. ..|.|||.
PGYVAPEVLECKKDKPYDKACDMWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase GL50803_11178.AA PSK 187-284 37 1.1e-23 72.29 In-house 164-258 (258) Show / Hide 
Range on Protein: 187-284
Range on HMM: 164-258/258
Sequence Identity: 37% (37 aa)

PEYISFMAPEVLRHQPYSTEPDIYAMGVTTYLLLGGVLPYEERDAGELLVLIEKGQWGFQNANFNGISANAKDFITQCLKPAISERITARKALQHPWL
||||   |||||   ||    |. |.|| .| |. |..|..      |   | .|.. .      ..|  ||||| . |    .||.||  |..|||.
PEYI---APEVLLRKPYTQSVDMWAVGVIAYILMSGIMPFDDDCRTRLYRHILTGKYNYYGQPWPSVSHLAKDFIDKLLEINQGERMTASQAMKHPWV
Kinase GL50803_11178.AA Pkinase 192-284 28 1.2e-23 84.72 Pfam 177-293 (293) Show / Hide 
Range on Protein: 192-284
Range on HMM: 177-293/293
Sequence Identity: 28% (33 aa)

FMAPEVLR-HQPYSTEPDIYAMGVTTYLLLGGVLPYEER------DAGELLVLIEKGQWGFQNANFNGIS-----------------ANAKDFITQCLKP
.|||||.| .|.|... |....|.. | .| | .|. ..      |  .....| .... |.  . . ||                  ..||||. ||..
YMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCK

AISERITARKALQHPWL
  ..|.||. .|||||.
DPKKRPTAEQILQHPWF
Kinase GL50803_11178.AA CAMK-Unique 9-137 19 1.8e-22 70.8 In-house 1-190 (363) Show / Hide 
Range on Protein: 9-137
Range on HMM: 1-190/363
Sequence Identity: 19% (37 aa)

ISYHK-IGESAVGMVYYGTEIRTNTPVAIKLICKASTKLDPYFM-------------------EREANTLLSITHENINRVRGI----YESAE-------
.  |. ||. . |.|| .. . | .  |.|.. |.  . . .                     .||.. ...  |.|| .. ..    .. ..       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------NLYIVMDLCVGNDVFTHAIR--------------------KKYYSE--DDAREIIRQICRALAYLHSRHIAHLGIKPENLLI
        ..||||..| |.|.|   ..                    . ..||   |.. |....  |.||.||  | |  .|.||...
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMV
Kinase GL50803_11178.AA CAMK2 192-284 37 1.2e-19 63.04 In-house 167-259 (259) Show / Hide 
Range on Protein: 192-284
Range on HMM: 167-259/259
Sequence Identity: 37% (35 aa)

FMAPEVLRHQPYSTEPDIYAMGVTTYLLLGGVLPYEERDAGELLVLIEKGQWGFQNANFNGISANAKDFITQCLKPAISERITARKALQHPWL
...||||| .||.   ||.| ||  |.|| |  |. . |   |   |  | . .   ... .  .||. | | |    . |||| .||.|||.
YLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDYPSPEWDTVTPEAKNLINQMLTINPKKRITADEALKHPWI
Kinase GL50803_11178.AA RSK 192-284 28 1.4e-19 68.45 In-house 174-278 (278) Show / Hide 
Range on Protein: 192-284
Range on HMM: 174-278/278
Sequence Identity: 28% (30 aa)

FMAPEVLR---HQP-YSTEPDIYAMGVTTYLLLGGVLPYEE---RDAGELLVLIEKGQWGFQNANFNGISANAKDFITQCLKPAISERIT-----ARKAL
.||||.|.   .|  ..   |..  ||  | .| | .|.      .. |..  |.||.  .   | . .|..|||.|...|.   . |..     |   .
YMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIK

QHPWL
||||.
QHPWF
Kinase GL50803_11178.AA CAMK2 7-137 31 6.6e-19 60.53 In-house 1-131 (259) Show / Hide 
Range on Protein: 7-137
Range on HMM: 1-131/259
Sequence Identity: 31% (42 aa)

YDISYHKIGESAVGMVYYGTEIRTNTPVAIKLI-CKASTKLDPYFMEREANTLLSITHENINRVRGIYESAENLYIVMDLCVGNDVFTHAIRKKYYSEDD
|.. .  .|  |  .|    .. |    | |.|  |  .  |   .||||     . | || |.    .  .  |.| ||  | ..|   . . |||| |
YQL-FEELGKGAFSVVRRCVKKCTGQEYAAKIINTKKLSARDHQKLEREARICRKLKHPNIVRLHDSIQEEGFHYLVFDLVTGGELFEDIVAREYYSEAD

AREIIRQICRALAYLHSRHIAHLGIKPENLLI
|   |.||  .... |.. | |  .||||||.
ASHCIQQILESVNHCHQNGIVHRDLKPENLLL
Kinase GL50803_11178.AA PSK 50-136 32 2.2e-18 55.05 In-house 42-128 (258) Show / Hide 
Range on Protein: 50-136
Range on HMM: 42-128/258
Sequence Identity: 32% (28 aa)

FMEREANTLLSITHENINRVRGIYESAENLYIVMDLCVGNDVFTHAIRKKYYSEDDAREIIRQICRALAYLHSRHIAHLGIKPENLL
| | | | |  . | .| .   ..|. . .|.||..  |   |   . |  ..| ||. . . .  .. |||.  | |   ||||||
FCENELNILRRVRHPYIIQLMEVFETQDRVYMVMEMATGGEMFDRIVAKGRFTERDATRVLQMVLDGMRYLHALRITHRDLKPENLL
Kinase GL50803_11178.AA RSK 53-136 32 1.2e-17 61.32 In-house 49-136 (278) Show / Hide 
Range on Protein: 53-136
Range on HMM: 49-136/278
Sequence Identity: 32% (29 aa)

REANTLLSIT-HENINRVRGIYESAENLYIVMDLCVGNDVFTHAIRKKY---YSEDDAREIIRQICRALAYLHSRHIAHLGIKPENLL
.| | |. .. | .| .    ..  . ||..|..| | . |||  ..|.    |||.|......|  |. .||...| |  .|||| |
TERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENIL
Kinase GL50803_11178.AA CAMKL 191-284 24 5.1e-14 40.99 In-house 198-297 (297) Show / Hide 
Range on Protein: 191-284
Range on HMM: 198-297/297
Sequence Identity: 24% (25 aa)

SFMAPEVLRH--QPYS-TEPDIYAMGVTTYLLLGGVLPYEER-------DAGELLVLIEKGQWGFQNANFNGISANAKDFITQCLKPAISERITARKALQ
..||||..    .||   . || ..||. | .. | || ..        |   .| ......  ..   .. .|  ..|.| . |..  ..|.|.   ..
PYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG--YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMN

HPWL
|||.
HPWM
Kinase GL50803_11178.AA TyrKc 8-284 20 3.3e-11 -41.45 SMART 1-280 (280) Show / Hide 
Range on Protein: 8-284
Range on HMM: 1-280/280
Sequence Identity: 20% (64 aa)

DISYHKIGESAVGMVYYGTEIRTNTPVAIKLICKASTKLDPYFMEREANTLLSI--THENINRVRGIYESA-------ENLYIVMDLCVGNDVFTHAIRK
    .|.|| | | || || .   ..||.| . . .       . |||. . ..   |.|| |  |.  .        | |.||| .. . |   .  ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

KY-YSEDDAREIIRQICRALAYLHSRHIAHLGIKPENLLITCNSQRPIVSHLNDSEGPQPSRELDEKYLVKLVDVMLSQYLHGG------EPLIRPEY--
.   . .|  ..  ||..  .||||... |  .   | |.. |                          ||  |  || ... .      .  .|.    
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH------------------------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHK

ISF-------MAPEVLRHQPYSTEPDIYAMGVTTY-LLLGGVLPYEE-----RDAGELLVLIEKGQWGFQNAN-----FNGISANAKDFITQCLKPAISE
 .        ||||....  ..|. |... ||. . ..  |  ||..      .. |.. ....|    | .|     | . ..   . ..|| .   ..
GGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPED

RITARKALQHPWL
| | .    |  .
RPTFSEI--HECF
Kinase GL50803_11178.AA Pkinase_Tyr 20-125 27 6e-06 20.86 Pfam 13-132 (270) Show / Hide 
Range on Protein: 20-125
Range on HMM: 13-132/270
Sequence Identity: 27% (33 aa)

GMVYYGTEI----RTNTPVAIKLICKASTKLD----PYFMEREANTLLSI-THENINRVRGIYE-SAEN--LYIVMDLCVGNDVFTHAIR----KKYYSE
|.|| ||       |..|||.| . | ..  .      ||. ||... ..  |.|| |  |.     |   .|||| .. . |  ..  .    |.  . 
GEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTM

DDAREIIRQICRALAYLHSRHI
 |  .. .||.....||.|...
KDLLQMCWQIAKGMEYLESKNC