Gene GL50803_11214 (G.lamblia)

GL50803_11214

Species: G.lamblia
Alias: GK005, GL50803_11214
External Links: GiardiaDB ,
Annotation:

Classification

Group: AGC
Family: PKA

Sequence

Name Sequence Type Origin Length Description Download
GL50803_11214.AA Protein None 359 None Fasta, JSON
GL50803_11214.kin_dom Protein Kinase Domain None 266 None Fasta, JSON

Protein domain

Protein domains of GL50803_11214.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_11214.AA AGC 17-282 29 1.1e-159 416.54 In-house 1-395 (395) Show / Hide 
Range on Protein: 17-282
Range on HMM: 1-395/395
Sequence Identity: 29% (117 aa)

LRHIKNIGSGSFGRVTLAQHI------DTGKYYAVKAMSKRK-IIALR--QVAHINNE------------CSILRVVR----------SPFIIR-QYGTY
 . .| || ||||.| |...       |||||||.| ..|.. |. ..  .|.|...|              ||  ..          .|||..  . ..
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDDKN--VYIILDFIQ---------GG-ELFYHLR---RYNKFPLQVVKFFAVE-------ILLALGYLHN-LGIAYRD-LKLENVLVDNTGHIKLADLG
||...  .|.......         || |||.||.   .. .|. ....|.| |       |.||| |||. .|| .|| ||.||.| |. |||||.| |
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

FAKRLVEKNADGDTVSQ--------------------------------------------LTFSIVG--TPEYLAPEIIRSTGHDMSADWWA--FGVLI
..|... .. .|   ||                                            .| ...|  ||||.||||.    .. ..|||.  .|.|.
LCKEGMNDGEKGQQ-SQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLM

YEMLTGSPPFFDDNPD----------MTCKKIL------GGKITFA----------SGFDKAAKDLIIRLLNPDKTRRLGASINN----GTADIMKHAFF
|||||| |||..|||.           . .||.        |..|           . |.. ||||| .||..| ..|||.  |.    |. .|..| .|
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase GL50803_11214.AA PKA 17-282 46 1.5e-122 413.41 In-house 1-263 (263) Show / Hide 
Range on Protein: 17-282
Range on HMM: 1-263/263
Sequence Identity: 46% (128 aa)

LRHIKNIGSGSFGRVTLAQHIDTGKYYAVKAMSKRKIIALRQVAHINNECSILRVVRSPFIIR-QYGTYQDDKNVYIILDFIQGGELFYHLRRYNKFPLQ
   |. .|.|||||| |..| ..|.||| | ..|..|. |.|| |..|| .||. ...|||..  |.|.|||.. | ......|||.|..||.  .|. .
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

VVKFFAV-EILLALGYLHNLGIAYRDLKLENVLVDNTGHIKLADLGFAKRLVEKNADGDTVSQLTFSIVGTPEYLAPEIIRST-GHDMSADWWAFGVLIY
. || |  .| ||| |||.. | ||||| || | |. ||||..| ||||.... .         |... ||||||||||| |. ||  | ||||.|.|||
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD-R---------TWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIY

EMLTGSPPFFDD--NPDMTCKKILGGKITFASGFDKAA---KDLIIRLLNPDKTRRLGASINNGTADIMKHAFF
|||.| |||.|.  .|  . .||. ||| | . ||..|   |||| .||..| |.|.|   | |. || .| .|
EMLAGYPPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKN-GVNDIKNHKWF
Kinase GL50803_11214.AA Akt 20-282 40 2.4e-109 350.71 In-house 4-264 (264) Show / Hide 
Range on Protein: 20-282
Range on HMM: 4-264/264
Sequence Identity: 40% (108 aa)

IKNIGSGSFGRVTLAQHIDTGKYY-AVKAMSKRKIIALRQVAHINNECSILRVVRSPFIIRQYGTYQDDKNVYIILDFIQGGELFYHLRRYNKFPLQVVK
.| .|.||||.| |..  ||.|.| | |. .|..||. .||.|.  |. ||  ...|||.  .   |. .. |...|...||||||||.| ..|. .  .
LKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSEDRAR

FFAVEILLALGYLHNLGIAYRD-LKLENVLVDNTGHIKLADLGFAKRLVEKNADGDTVSQLTFSIVGTPEYLAPEIIRSTGHDMSADWWA-FGVLIYEML
|.. || ||...||. .| ||| ||.||.|.|..|||.|.| | .|. . |. |       | .. ||||||||||.  .||....|||. .|...|||.
FYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHD------KTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMM

TGSPPFFDDNPDMTCKKILGGKITFA--SGFDKAAKDLIIRLLNPDKTRRLGASINNGTADIMKHAFF
.| |||.... .   |||. ... |   . .....||||..||| |...|||.  .|.. .|. | .|
CGRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGG-GPNDAQEIKRHPWF
Kinase GL50803_11214.AA SGK 18-282 36 2.9e-98 304.09 In-house 2-283 (283) Show / Hide 
Range on Protein: 18-282
Range on HMM: 2-283/283
Sequence Identity: 36% (105 aa)

RHIKNIGSGSFGRVTLAQHIDT------------------GKYYAVKAMSKRKII-------ALRQVAHINNEC-SILRVVRSPFIIRQYGTYQDDKNVY
. .| || ||||.| ...| |.                  .| ||.|  .|  ||       .  .. ||  |   ||  ...|||.      | ..  |
DFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKLY

IILDFIQGGELFYHLRRYNKFPLQVVKFFAVEILLALGYLHNLGIAYRDLKLENVLVDNTGHIKLADLGFAKRLVEKNADGDTVSQLTFSIVGTPEYLAP
  .|...|||.||||.| ..||  ...| | || .||.||| . | ||||| ||.| |  ||..| | | .|  ...|       . ||.. ||||||||
FVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTN-------DTTFTFCGTPEYLAP

EIIRSTGHDMSADWWAFGVLIYEMLTGSPPFFDDNPDMTCKKILGGKITFASGFDKAAKDLIIRLLNPDKTRRLGASINNGTADIMKHAFF
|..|  .|| . |||  | . |||..| |||.. |      .|. ... .  ..  .|.|||  ||. |.. |||.  ... ..| .| ||
EVLRKQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGT--KRDFMEIKNHPFF
Kinase GL50803_11214.AA S_TKc 17-282 31 3.7e-95 323.36 SMART 1-231 (231) Show / Hide 
Range on Protein: 17-282
Range on HMM: 1-231/231
Sequence Identity: 31% (87 aa)

LRHIKNIGSGSFGRVTLAQHIDTGKYYAVKAMSKRKIIALRQVAHINNECSILRVVRSPFIIRQYGTYQDDKNVYIILDFIQG--GELFYHLRRYNK---
 . .. ||.|.||.| ...|..||...|.| ..           || .| .||.  . |.|.. |...|| ...|...... |  |.|| .......   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FPLQVVKFFAVEILLALGYLHNLGIAYRDLKLENVLVDNTGHIKLADLGFAKRLVEKNADGDTVSQLTFSIVGTPEYLAPEIIRSTGHDM-SADWWA
   ||  ...|.. .|..|| |.|..|| .|||| ||.|.|.  |||..| |.|..|               ...|||.|.|||..   |..  ..|||.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------------TTFCGTPWYMAPEVL---GYGKCKCDWWS

FGVLIYEMLTGSPPFFDDNPDMTCKKILGGKITFASGFDKAAKDLIIRLLNPDKTRRLGASINNGTADIMKHAFF
.|...||||.| |||   ...|. |||.          .. |||.| ..|. | ..|..| . ..  ||..| .|
CGCILYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase GL50803_11214.AA RSK 20-282 36 1e-91 311.0 In-house 1-278 (278) Show / Hide 
Range on Protein: 20-282
Range on HMM: 1-278/278
Sequence Identity: 36% (104 aa)

IKNIGSGSFGRVTLAQHI---DTGKYYAVKAMSKRKIIALRQ-VAHINNECSILRVVR-SPFIIRQYGTYQDDKNVYIILDFIQGGELFYHLRRYNK---
.|  | |..| | | . .   |||..||.|  .|.||..    ..|   | .||  .. .|||.. . ..|... .|.|.... |||||.||..      
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FPLQVVKFFAVEILLALGYLHNLGIAYRDLKLENVLVDN---TGHIKLADLGFAKRLVEKNADGDTVS--QLTFSIVGTPEYLAPEIIR----STGHDMS
|    ..| . || ||. .|| .|| .||||.||.| |.    ||||| | ||.| .          .  |.| . ..| ||.|||...      ||| .
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF--------RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKA

ADWWAFGVLIYEMLTGSPPFFD---DNPDMTCKKILGGK--ITFA--SGFDKAAKDLIIRLLNPDKTRRLGASINNGTADIMKHAFF
.||| .|||.|||||| |||     .|.. . |.|. ||   |.   .   ..||||| ..|  |  .|||.   .....| .|..|
CDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCG-PQDAEEIKQHPWF
Kinase GL50803_11214.AA AktR 18-282 39 1.8e-91 310.18 In-house 2-268 (268) Show / Hide 
Range on Protein: 18-282
Range on HMM: 2-268/268
Sequence Identity: 39% (107 aa)

RHIKNIGSGSFGRVTLAQHI-DTGKYYAVKAMSKRKIIALRQVAHINNECSILR-VVRSPFIIRQYGTYQDDKNVYIILDFIQGGELFYHLRRYNKFPLQ
. .|..|.| ||.| |.|.  |..|.|| |  .| ||| ..|  |. .|  |.   .. |||.. . . |.... ..|.....|||||.||.. .||  .
HVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSEE

VVKFFAVEILLALGYLHNL-GIAYRDLKLENVLVDNTGHIKLADLGFAKRLVEKNADGDT-VSQLTFSIVGTPEYLAPEIIRS-TGHDMSADWWAFGVLI
...|....||||| |||.   | ||||| || | |  ||.|..| | .|        ..   .... |..|||||.|||.|.   ||. |.||||||..|
QARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK------LQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFI

YEMLTGSPPFFDDNPDMTCKKILGGK---ITFASGFDKAAKDLII-RLLNPDKTRRLGASINNGTADIMKHAFF
|||.|| |||...|     .||.      ... | | ...||||  .||. . . ||| ...||. .| .| .|
YEMVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLG-YYCNGWEEIKSHPWF
Kinase GL50803_11214.AA Pkinase 17-282 29 1.6e-87 301.86 Pfam 1-293 (293) Show / Hide 
Range on Protein: 17-282
Range on HMM: 1-293/293
Sequence Identity: 29% (90 aa)

LRHIKNIGSGSFGRVTLAQHIDTGKYYAVKAMSKRKIIALRQVAHIN-NECSILRVVRSPFIIRQYGTYQDDKNVYIILDFIQGG----ELFYHLR--RY
.. .. |||||||.| ...|..||| .||| ..||..    ...|.. .|..|.. ...|.|.| |....|....|..... .||    .|| ...  |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NKF--PLQVVKFFAVEILLALGYLHNLGIAYRDLKLENVLVDNTGHI----KLADLGFAKRLVEKNADGDTVSQLTFSIVGTPEYLAPEIIR-STGHDMS
..|  . ...||.. .|| .| |.|. || .||||.||.|.||.|||    |..| |.|| .          .. . ...|||.|.|||.|| ..... .
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

ADWWAFGVLIYEMLTGSPPFFDD------NPDMTCKKILGGKITFASGFD---------------------KAAKDLIIRLLNPDKTRRLGASINNGTAD
.|.|..|...||||.| ||| ..      ...   ..|.|... | .  .                     ...||.| ..|..| ..|..       ..
VDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT------AEQ

IMKHAFF
|..| .|
ILQHPWF
Kinase GL50803_11214.AA Ciliate-E2 17-282 25 3.4e-82 279.37 In-house 1-365 (365) Show / Hide 
Range on Protein: 17-282
Range on HMM: 1-365/365
Sequence Identity: 25% (97 aa)

LRHIKNIGSGSFGRVTLAQHIDTG-----------------------KYYAVKAMSKRKIIALRQVAHIN----------NECSILRVVRSPFIIRQYGT
   || ||.|.|| | ..... ..                       |.||.| |.|..|... |. ||.          || .||. . .|.||. | .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YQ--DDKNVYIILDFIQGGELFYHLR------------------RYNK-FPLQVVK-------FFAVEILLALGYLHNLG-IAYRDLKLENVLVDNTGHI
.|  ||.|.|......|||.||....                  .  | .  |...       |....|.||| |||. . | .||.|.||.|.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLADLGFAKRLVEKNADGD----------------TVS--------QLTFSIVGTPEYLAPEIIRSTG---------HDMSADWWAFGVLIYEMLTGSPP
|..|.|..|.. ..| ..                 | .        .....|.|||.|.||||... .         .| ..|.|..||..||||.| ||
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FFDDNPDMTCKKILGGKITFA------------------SGFDKAAKDLIIR----LLNPDKTRRLGASINNGTADIMKHAFF
|         ..|. .|| |                      .. .|||| .    .|. |   |..     |  .|..| .|
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT-----GWEQILNHPWF
Kinase GL50803_11214.AA RSK 20-282 38 3.7e-77 262.65 In-house 4-271 (271) Show / Hide 
Range on Protein: 20-282
Range on HMM: 4-271/271
Sequence Identity: 38% (106 aa)

IKNIGSGSFGRVTLAQHI---DTGKYYAVKAMSKRKIIALRQVAHINNECSILRVVRSPFIIRQYGTYQDDKNVYIILDFIQGGELFYHLRRYNKFPLQV
.. || |||. | . . .   ||...||.|   | .. .  .     .|  ||| . .|||.. .  .|| ..||.|.|| .||.|| .| .   |. . 
HECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFSERE

VKFFAVEILLALGYLHNLGIAYRDLKLENVLVDNT----GHIKLADLGFAKRLVEKNADGDTVSQLTFSIVGTPEYLAPEIIRSTGHDMSADWWAFGVLI
||| . ||.||. ||| .||..|||| ||.|.| .    ||||..|.|||| |  .|        .. .  .| .|.|||...  |||...||| |||| 
VKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDEN-------GMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLM

YEMLTGSPPFF---DDNPDMTCKKILGGKITFASGF----DKAAKDLIIRLLNPDKTRRLGASINNGTADIMKHAFF
|||||| .||    .| |.   ..|  |.... .|      . ||||. ..|  |...||||   ||...| .|..|
YEMLTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGP-NGVEQIKQHPWF
Kinase GL50803_11214.AA MAST 181-282 36 7.9e-45 134.47 In-house 227-337 (337) Show / Hide 
Range on Protein: 181-282
Range on HMM: 227-337/337
Sequence Identity: 36% (42 aa)

SIVGTPEYLAPEIIRSTG-HDMSADWWAFGVLIYEMLTGSPPFFDDNPD-MTCKKILG--GKITFASG--------FDKAAKDLIIRLLNPDKTRRLGAS
...|||.|.|||.|  .| .  ..|||. |. .|| |.|.|||..|.|  |.  .|.    .| . ..        . . |.|||..||.|.   |||| 
QCCGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGA-

INNGTADIMKHAFF
  || ..|..|.||
--NGADEIKQHPFF
Kinase GL50803_11214.AA MAST 19-163 34 6.1e-43 128.6 In-house 3-150 (337) Show / Hide 
Range on Protein: 19-163
Range on HMM: 3-150/337
Sequence Identity: 34% (51 aa)

HIKNIGSGSFGRVTLAQHIDTGKYYAVKAMSKRKIIALRQVAHINNECSILRVVRSPFIIRQYGTYQD--DKNVYIILDFIQGGELFYHLRRYN-KFPLQ
.|| |. | .|.| |..|..|.. .| | . .. .|   || ... |  || ..  ||.   . . |   .| ....... .||  . .|| |.  .|  
FIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMPEW

VVKFFAVEILLALGYLHNLGIAYRDLKLENVLVDNTGHIKLADLGFAK
 .|.   |. |.| |||. ||  |||| .|.| | .|||||.| |..|
MAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSK
Kinase GL50803_11214.AA MAST 18-163 33 1.4e-42 134.83 In-house 2-147 (334) Show / Hide 
Range on Protein: 18-163
Range on HMM: 2-147/334
Sequence Identity: 33% (49 aa)

RHIKNIGSGSFGRVTLAQHIDTGKYYAVKAMSKRKIIALRQVAHINNECSILRVVRSPFIIRQYGTYQDDKNVYIILDFIQGGELFYHLRRYNKFPLQVV
 .|| |. | .|.| |. |..|.. .|.| . |.  |   .| . . |  || ....||.   . . | .......... .|| .. .|. |. |.   .
EFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWMA

KFFAVEILLALGYLHNLGIAYRDLKLENVLVDNTGHIKLADLGFAK
|.   |. |.| |||. ||  |||| .|.| |..|||||.| |..|
KMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSK
Kinase GL50803_11214.AA MAST 181-282 39 1.6e-40 128.11 In-house 223-334 (334) Show / Hide 
Range on Protein: 181-282
Range on HMM: 223-334/334
Sequence Identity: 39% (45 aa)

SIVGTPEYLAPEIIRSTG-HDMSADWWAFGVLIYEMLTGSPPFFDDNPDMTCKKILGGK---ITFASG--------FDKAAKDLIIRLLNPDKTRRLGAS
...|||.|.|||.|  .| | .. |||. |. .|| |.| |||.||.|...  .||  .   | .  |        . . |.|||..||.||   ||||.
QCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGAN

INNGTADIMKHAFF
  || .....| ||
--NGADEVKQHPFF
Kinase GL50803_11214.AA TyrKc 17-277 19 5.3e-12 -28.65 SMART 1-280 (280) Show / Hide 
Range on Protein: 17-277
Range on HMM: 1-280/280
Sequence Identity: 19% (56 aa)

LRHIKNIGSGSFGRVTLAQHIDTGKYYAVKAMSKRKIIALRQVAHINNECSILRVV--RSPFIIRQYGTYQDD-------KNVYIILDFIQGGELFYHLR
.. .| .|.| ||.| ... .      ||| . . .      .. . .| .|.. .  . | |.| ||   ..       . ..|.. .  .| |  .||
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RYNK-FPLQVVKFFAVEILLALGYLHNLGIAYRDLKLENVLVDNTGHIKLADLGFAKRLVEKNADGDTVSQLTFSI---VGTPE-----YLAPEIIRSTG
.. . ....    |.. |     |||  ..  |||   |.||.. ...| .| | .. . .. . |  .|. . .     |.        .||| |.   
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG--ESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

HDMSADWWAFGVLIYEMLT-GSPPFFD------DNPDMTCKKILGGKITFASG--------FDKAAKDLIIRLLNPDKTRRLGASINNGTADIM
     | |.|||...|..| | .|  .      .| ..  .   |.                 ..  ... .  . |   |   |      ...
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI---HECF
Kinase GL50803_11214.AA S_TK_X 283-331 13 0.000179 14.56 SMART 1-79 (79) Show / Hide 
Range on Protein: 283-331
Range on HMM: 1-79/79
Sequence Identity: 13% (11 aa)

SGVNWSWFEK--KVVKAPIVPKLT----DPADTANYE-DYLD-----ENGNF------------------EEDEIDYEN
.|..|   ..  | ...|..||..    .| || | . .. .      . .                   .  . .| .
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase GL50803_11214.AA Pkinase_Tyr 17-160 22 0.00084 13.5 Pfam 1-156 (270) Show / Hide 
Range on Protein: 17-160
Range on HMM: 1-156/270
Sequence Identity: 22% (36 aa)

LRHIKNIGSGSFGRVTLAQHI----DTGKYYAVKAMSKRKIIALRQ--VAHINNECSILRVV-RSPFIIRQYGTYQ-DDKN--VYIILDFIQGGELFYHL
.. .| .|.|.||.| ..       .|.   ||| .  .     .|   .   .| .|..   . | |.| ||    ...   .||.. . ..| |  .|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML--KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

RRY----NKFPLQVVKFFAVEILLALGYLHNLGIAYRDLKLENVLVDNTGHIKLADLG
|.     ......    ....|  .. ||.. ..  |||   |.||......| .| |
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase GL50803_11214.AA Pkinase_Tyr 206-222 47 0.044244 7.67 Pfam 198-216 (270) Show / Hide 
Range on Protein: 206-222
Range on HMM: 198-216/270
Sequence Identity: 47% (9 aa)

WAFGVLIYEMLT-GSPP-F
|.||||..|..| |  | .
WSFGVLMWEIFTYGEQPTY