GL50803_11355

Species: G.lamblia
Alias: GK236, GL50803_11355
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Nek
Subfamily: Nek-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_11355.AA Protein None 1412 None Fasta, JSON
GL50803_11355.kin_dom Protein Kinase Domain None 213 None Fasta, JSON

Protein domain

Protein domains of GL50803_11355.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_11355.AA Trio 234-259 53 1.4e-09 20.07 In-house 233-258 (258) Show / Hide
Range on Protein: 234-259
Range on HMM: 233-258/258
Sequence Identity: 53% (14 aa)

DFIDKLLVEDDRIRPTATEALQNPKF
.|| |.|.|| . ||.| |.||.| |
HFICKVLQEDPWKRPCASECLQHPWF

Kinase GL50803_11355.AA MLCK 229-259 51 2.2e-08 17.68 In-house 227-257 (257) Show / Hide
Range on Protein: 229-259
Range on HMM: 227-257/257
Sequence Identity: 51% (16 aa)

SEEIADFIDKLLVEDDRIRPTATEALQNPKF
|.|  |||..|||.| . |.||.|.|| | .
SDEAKDFISRLLVKDKEKRMTAHECLQHPWL

Kinase GL50803_11355.AA CAMK 223-259 24 1.9e-07 19.31 In-house 381-425 (425) Show / Hide
Range on Protein: 223-259
Range on HMM: 381-425/425
Sequence Identity: 24% (11 aa)

DLRSNYSEE--------IADFIDKLLVEDDRIRPTATEALQNPKF
.  .. |.|          |.| |.|. |   |.|....|. | .
EWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase GL50803_11355.AA CK2 229-259 45 4.3e-07 16.41 In-house 258-288 (288) Show / Hide
Range on Protein: 229-259
Range on HMM: 258-288/288
Sequence Identity: 45% (14 aa)

SEEIADFIDKLLVEDDRIRPTATEALQNPKF
..|. ||.||.|. |   | || ||.. | |
HPEAIDFLDKMLRYDHQERITAKEAMEHPYF

Kinase GL50803_11355.AA DAPK 226-259 50 9.5e-07 14.29 In-house 231-264 (264) Show / Hide
Range on Protein: 226-259
Range on HMM: 231-264/264
Sequence Identity: 50% (17 aa)

SNYSEEIADFIDKLLVEDDRIRPTATEALQNPKF
|. ||.  ||| .||| | . |.||.|.|| |  
SCTSEHAKDFIRRLLVKDPEKRMTAEECLQHPWI

S_TKc GL50803_11355.AA S_TKc 8-259 15 2e-06 -82.99 SMART 1-231 (231) Show / Hide
Range on Protein: 8-259
Range on HMM: 1-231/231
Sequence Identity: 15% (44 aa)

ITNLGALK----SSCYIMKESSPALVHTQLIPTDLMPDKAVWMMRCVIEHFSVASSPFLVDIKTVAAPYAGVIKFREKWY----------VGT---SLRS
 . |  .     ...|  .. .               .. .  . ..          ..  |.        ..|. . ..          ...   .|..
YEILRKIGKGAFGKVYKCRHKK---------------TGRIVAIKIIK-------EHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFD

VLQTQVASGTR--FSESTIWRLAYGILKALAFMHTPSSSVQKLTGQYCFVHGHITPDTVFLSTNQMPRIGSLHCCTLTSCCLPNAETGGRFKPYLPLDID
... .   |.|  |.| ......| |..||...|           .  ..|  . |. ..|..     |.    ...                     . 
YIKKRGRHGLRFPFPE-HARFYMYQICCALEYCH-----------SHGIIHRDLKPENILLDE--HIKICDFGLARQL------------------TTFC

SSIF---PPLITPGYEP-LVDIWSLGILLLQACA---------VPRGDLRSNYSEEIADFIDKLLVEDDRIRPTATEALQ-------NPKF
 . .   | ..  || .  .|.||.|..|   ..         .    ..   |.|  |||.|.|. | . |||| ||||        | |
GTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLCGYPPFPQMQMMFKKIG---SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase GL50803_11355.AA STE 204-259 18 3e-06 18.42 In-house 249-359 (359) Show / Hide
Range on Protein: 204-259
Range on HMM: 249-359/359
Sequence Identity: 18% (21 aa)

VDIWSLGILL-------LQACAVPRG---------------------------DLRS-------------------NYSEEIADFIDKLLVEDDRIRPTA
.||||||...          .  .                              | .                   ..|.|  |||.| |. | . ||||
CDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTA

TEALQ--NPKF
.. |.   | .
SQLLKSEHPFI

Kinase GL50803_11355.AA NEK 226-259 27 8e-06 16.94 In-house 251-286 (286) Show / Hide
Range on Protein: 226-259
Range on HMM: 251-286/286
Sequence Identity: 27% (10 aa)

SN--YSEEIADFIDKLLVEDDRIRPTATEALQNPKF
|.  ||..  ..| ..|  |   ||.... |..|  
SHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI

Kinase GL50803_11355.AA RAD53 229-259 41 1.2e-05 12.18 In-house 275-305 (305) Show / Hide
Range on Protein: 229-259
Range on HMM: 275-305/305
Sequence Identity: 41% (13 aa)

SEEIADFIDKLLVEDDRIRPTATEALQNPKF
||| .|.|...|. |   |.|. |||. | .
SEEAKDLIKWMLCVDPEKRYTIDEALNHPWM

Kinase GL50803_11355.AA Ciliate-E2 227-259 31 9.3e-05 12.24 In-house 328-365 (365) Show / Hide
Range on Protein: 227-259
Range on HMM: 328-365/365
Sequence Identity: 31% (12 aa)

NYSEEIADFIDK----LLVEDDRIRPT-ATEALQNPKF
. |.|  |.| |    .|. |   |.| . ..|..| |
KWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase GL50803_11355.AA PAKB 229-259 38 0.000521 10.71 In-house 222-252 (252) Show / Hide
Range on Protein: 229-259
Range on HMM: 222-252/252
Sequence Identity: 38% (12 aa)

SEEIADFIDKLLVEDDRIRPTATEALQNPKF
| .  .|.|..|| |   | || | |. | .
SPRLREFLDRMLVRDPNQRWTAQELLRHPFL

Kinase GL50803_11355.AA Pkinase 217-259 25 0.002044 13.16 Pfam 228-293 (293) Show / Hide
Range on Protein: 217-259
Range on HMM: 228-293/293
Sequence Identity: 25% (17 aa)

CAVPRGDLRSNYS-----------------------EEIADFIDKLLVEDDRIRPTATEALQNPKF
| . ...|.....                       ||  |||...|  |   ||||...|| | |
CRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase GL50803_11355.AA CAMK 198-213 50 0.003514 5.3 In-house 309-324 (425) Show / Hide
Range on Protein: 198-213
Range on HMM: 309-324/425
Sequence Identity: 50% (8 aa)

PGYEPLVDIWSLGILL
|.| | .|.||.|..|
PYYGPKCDMWSCGVIL

Kinase GL50803_11355.AA RAD53 199-213 53 0.004007 4.57 In-house 217-231 (305) Show / Hide
Range on Protein: 199-213
Range on HMM: 217-231/305
Sequence Identity: 53% (8 aa)

GYEPLVDIWSLGILL
|| . ||.||.| .|
GYTKKVDCWSMGCIL

Kinase GL50803_11355.AA PAKB 200-214 60 0.004203 7.39 In-house 172-186 (252) Show / Hide
Range on Protein: 200-214
Range on HMM: 172-186/252
Sequence Identity: 60% (9 aa)

YEPLVDIWSLGILLL
|.. ||||||||...
YGTEVDIWSLGIMVI

Kinase GL50803_11355.AA NEK 98-122 36 0.007688 6.3 In-house 107-131 (286) Show / Hide
Range on Protein: 98-122
Range on HMM: 107-131/286
Sequence Identity: 36% (9 aa)

SGTRFSESTIWRLAYGILKALAFMH
.|. |.|..||.  . ...|| .||
KGKYFEEEQIWDWFIQMCLALKYMH

Kinase GL50803_11355.AA Ciliate-E2 199-213 60 0.008448 5.42 In-house 272-286 (365) Show / Hide
Range on Protein: 199-213
Range on HMM: 272-286/365
Sequence Identity: 60% (9 aa)

GYEPLVDIWSLGILL
||   .||||||..|
GYDYKCDIWSLGVIL

Kinase GL50803_11355.AA STE 85-122 26 0.053036 3.01 In-house 121-169 (359) Show / Hide
Range on Protein: 85-122
Range on HMM: 121-169/359
Sequence Identity: 26% (13 aa)

GTSLRSVLQ-TQVASG---------TRFSESTIWRLAYGILKA-LAFMH
| ||..... .    .         .||.|| | . .. |||. |.. |
GGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLH

Kinase GL50803_11355.AA Pkinase 198-213 50 0.322083 5.39 Pfam 187-202 (293) Show / Hide
Range on Protein: 198-213
Range on HMM: 187-202/293
Sequence Identity: 50% (8 aa)

PGYEPLVDIWSLGILL
..| | ||.||.|..|
QYYGPKVDMWSCGCIL

Pkinase GL50803_11355.AA Pkinase 83-122 23 0.355133 5.24 Pfam 81-125 (293) Show / Hide
Range on Protein: 83-122
Range on HMM: 81-125/293
Sequence Identity: 23% (11 aa)

YVGT-----SLRSVLQTQVASGTRF--SESTIWRLAYGILKALAFMH
|..      .| ....|   ....|  || .. . .| ||..|...|
YCEGGLYVMDLFDYIST--WRHGCFYFSEWECKFYMYQILRGLEYCH

Ank GL50803_11355.AA Ank 374-394 33 0.004928 15.2 Pfam 1-21 (33) Show / Hide
Range on Protein: 374-394
Range on HMM: 1-21/33
Sequence Identity: 33% (7 aa)

AGMSALMLAAIYNQAEMVHLL
 |...|.||......|.| .|
DGFTPLHLACRCGHTEVVKML

Ank GL50803_11355.AA Ank 509-541 33 0.001012 17.68 Pfam 1-33 (33) Show / Hide
Range on Protein: 509-541
Range on HMM: 1-33/33
Sequence Identity: 33% (11 aa)

VGETCLHKAARLGYAKIVEILAPYEANIACRDS
 |.|.|| |.| |....|. |  . |..  .| 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank GL50803_11355.AA Ank 586-605 20 13.678185 2.78 Pfam 1-20 (33) Show / Hide
Range on Protein: 586-605
Range on HMM: 1-20/33
Sequence Identity: 20% (4 aa)

KKTTPLIAAVLSKDINIIRL
   |||  |... .......
DGFTPLHLACRCGHTEVVKM

Ank GL50803_11355.AA Ank 617-637 33 0.011593 13.86 Pfam 1-21 (33) Show / Hide
Range on Protein: 617-637
Range on HMM: 1-21/33
Sequence Identity: 33% (7 aa)

DGYTALMHAVLTNQLSAVILL
||.|.|. |.. .... | .|
DGFTPLHLACRCGHTEVVKML

Ank GL50803_11355.AA Ank 651-671 38 0.205061 9.36 Pfam 1-21 (33) Show / Hide
Range on Protein: 651-671
Range on HMM: 1-21/33
Sequence Identity: 38% (8 aa)

EGLTSLWLAYLQGNSAIVRLL
.| | | || . |.  .|..|
DGFTPLHLACRCGHTEVVKML

Ank GL50803_11355.AA Ank 991-1016 30 0.00238 16.34 Pfam 1-25 (33) Show / Hide
Range on Protein: 991-1016
Range on HMM: 1-25/33
Sequence Identity: 30% (8 aa)

NGTTALMLAVAMNSLTLVRLLVGEKG
.| |.|.||. ....  |..|.. .|
DGFTPLHLACRCGHTEVVKMLLQ-HG

Ank GL50803_11355.AA Ank 1094-1113 40 45.363277 0.9 Pfam 4-23 (33) Show / Hide
Range on Protein: 1094-1113
Range on HMM: 4-23/33
Sequence Identity: 40% (8 aa)

TALGFAAYRGATRIVQSLLG
|.|  |...| |..|. ||.
TPLHLACRCGHTEVVKMLLQ

Ank GL50803_11355.AA Ank 1123-1144 45 0.000177 20.41 Pfam 1-22 (33) Show / Hide
Range on Protein: 1123-1144
Range on HMM: 1-22/33
Sequence Identity: 45% (10 aa)

NHRTPLMLAAITGHLATIKLLL
. .|||.||.. ||.  .|.||
DGFTPLHLACRCGHTEVVKMLL

Ank GL50803_11355.AA Ank 1154-1186 33 0.000381 19.21 Pfam 1-33 (33) Show / Hide
Range on Protein: 1154-1186
Range on HMM: 1-33/33
Sequence Identity: 33% (11 aa)

DGYTALAIATYHGHSDVVEFLFPYEAHICTKTG
||.|.| .| ..|| .||..|  . | .. .. 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank GL50803_11355.AA Ank 1294-1314 47 8.4e-05 21.57 Pfam 1-21 (33) Show / Hide
Range on Protein: 1294-1314
Range on HMM: 1-21/33
Sequence Identity: 47% (10 aa)

CGRTALMIAAACNHTACVQML
.|.|.|..|. |.|| .|.||
DGFTPLHLACRCGHTEVVKML

Ank GL50803_11355.AA Ank 1261-1293 24 0.02852 12.45 Pfam 1-33 (33) Show / Hide
Range on Protein: 1261-1293
Range on HMM: 1-33/33
Sequence Identity: 24% (8 aa)

QGTTLLMYCCKRNLHSFVDVLVRRKKGLGLQDH
 | | |.. |... .. |  |. .   . .|| 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank GL50803_11355.AA Ank 1325-1350 30 10.005448 3.27 Pfam 1-25 (33) Show / Hide
Range on Protein: 1325-1350
Range on HMM: 1-25/33
Sequence Identity: 30% (8 aa)

YRTTALISATKSGAYEAAELLLDEAG
.  |.|  | ..| .| ...||. .|
DGFTPLHLACRCGHTEVVKMLLQ-HG

Ank GL50803_11355.AA Ank 1355-1384 20 37.949519 1.18 Pfam 1-29 (33) Show / Hide
Range on Protein: 1355-1384
Range on HMM: 1-29/33
Sequence Identity: 20% (6 aa)

GDYTALYYAVGECHNDRLIELLLPYEASIC
  .|.| .|.    . . ...|| . |...
DGFTPLHLACRCG-HTEVVKMLLQHGADVN