Gene GL50803_137719 (G.lamblia)

GL50803_137719

Species: G.lamblia
Alias: GL50803_137719, GK072
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Nek
Subfamily: Nek1

Sequence

Name Sequence Type Origin Length Description Download
GL50803_137719.AA Protein None 466 None Fasta, JSON
GL50803_137719.kin_dom Protein Kinase Domain None 256 None Fasta, JSON

Protein domain

Protein domains of GL50803_137719.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_137719.AA NEK 4-259 38 6.1e-105 354.95 In-house 1-286 (286) Show / Hide 
Range on Protein: 4-259
Range on HMM: 1-286/286
Sequence Identity: 38% (110 aa)

YTVIRKIGEGSFGECFLCCDKRTGLH-----VVIKEISMEDMQDTEVRNTE-RESAILLTMDHPNIVRGIESFKEDG--FLYIAMTYCE-HGELTSL---
|..|.|||.||||..... .|..| |     .|.|.|.|. |.. | .|.   |  ||  ..|||||. ..|| |..  .|.| | |||  | |  .   
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

IKRHHKSQMHFEESQVLRWIAQLASALWYIHSK-----GLIHRDLKSQNIFLDQD----LNVHIGDFGIARTINPG-SMAST-FIGSPLYMSPELIQGTS
||.. ..  .|||.|...| .|...|| |.|..       .|||.|.|||||. .     || ||||||..  | . .||.| ..| | |||||..|. .
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKP

YNSQSDMWSLGCMIFEILCL--KTAFQAK--NINTLIMKIVSG-KVPELPGI--YSSKLRDICLNLLNQVPDQRMTAAQLCGHDLI
||. ||.||||| ..|. .|  | .|.|.  |.. |.|||. | . | .|    ||..|...  ..|.  |.|| .. |.  . .|
YNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase GL50803_137719.AA NEK8 4-259 35 2.3e-88 252.39 In-house 1-278 (278) Show / Hide 
Range on Protein: 4-259
Range on HMM: 1-278/278
Sequence Identity: 35% (98 aa)

YTVIRKIGEGSFGECFLCCDKRTG--LHVVIKEISMEDMQDTEVRNTERESAILLTMDHPNIVRGIESFKEDGFLYIAMTYCEHGELTSLIKRHHKSQMH
|. || .| |.||.| |.  |  .    |..|.| |..|   | .    |  .|   .||||.  ...| ||. | |.| |.. | |  .|  | .   .
YERIRVVGRGAFGICWLYRRKEDQSHHLVIWKQINMHRMSEKERQMAQNEIQVLSMLQHPNIISYYDHFMEDNTLMIEMEYADGGTLYQMIQ-HQQNKLF

FEES----------------QVLRWIAQLASALWYIHSKGLIHRDLKSQNIFLDQD-LNVHIGDFGIARTINPGSMAST---FIGSPLYMSPELIQGTSY
.||                 ..|    |  ||. ..|...  ||||| ||||.. .   | ||||||.   |  . ..|    .| |.|||||. .| .|
EEERQLKQVNHCFNIYFNEQMILWYFFQMCSAVHHMHQHNILHRDLKTQNIFMTRHRMVVKIGDFGISKIMNTKYHMQTTKTVVGTPYYMSPEMCEGKPY

NSQSDMWSLGCMIFEILCLKTAFQAKNINTLIMKIVSG-KVPELPGIYSSKLRDICLNLLNQVPDQRMTAAQLCGHDLI
|  ||||.||| ..| .||| || | |   |..||... .   ... ||. .|   .|.| | |.|| .|.|.    |.
NQKSDMWALGCVLYEMCCLKRAFEASNLPALVWKIMQCRAYEPISDHYSNEMRMLVHNCLQQDPEQRPSASQIMAMPLC
Kinase GL50803_137719.AA S_TKc 4-259 32 9.1e-87 295.48 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-259
Range on HMM: 1-231/231
Sequence Identity: 32% (88 aa)

YTVIRKIGEGSFGECFLCCDKRTGLHVVIKEISMEDMQDTEVRNTERESAILLTMDHPNIVRGIESFKEDGFLYIAMTYCEH--GELTSLIKRHHKSQMH
|...||||.|.||....| .|.|| .| ||.|.         ....|| .||   .|||||. ...| . ..||. | ||..  |.| ..||.. .   .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--FEESQVLRWIAQLASALWYIHSKGLIHRDLKSQNIFLDQDLNVHIGDFGIARTINPGSMASTFIGSPLYMSPELIQGTSYNS-QSDMWSLGCMIFEIL
  | | .. ....|...|| |.||.| |||||| .||.||.  .. |.|||.|| .      .||.|.| ||.||..   .|.   .|.||.||...| |
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

CLKTAFQAKNINTLIMKIVSGKVPELPGIYSSKLRDICLNLLNQVPDQRMTAAQLCG-------HDLI
| .. |.  ...... ||.           |. ..|.  ..|.  |..|.|| ..         |  .
CGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase GL50803_137719.AA NEK1 4-263 41 1.1e-83 284.37 In-house 1-276 (276) Show / Hide 
Range on Protein: 4-263
Range on HMM: 1-276/276
Sequence Identity: 41% (115 aa)

YTVIRKIGEGSFGECFLCCDKRTGLHVVIKEISMEDMQDTEVRNTERESAILLTMDHPNIVRGIESFKEDGF--LYIAMTYCEHGELTSLIKRHHKSQMH
|..|..|||||||  .|  .|  | | |||||. . ||. |  .  .| |||  |.|||||.  ||| | |   ||| | ||. | |   |.|   .   
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGKL

FEESQVLRWIAQLASALWYIHSKGLIHRDLKSQNIFLD--QDL---------------NVHIGDFGIARTIN-PGSMASTFIGSPLYMSPELIQGTSYNS
| | | . |  |.  || .||..  .|||.|||||||   ..                 | .|||||||. | . . |.| || | | |||..|   || 
FSEDQIMHWFCQICLALNHIHDRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPEICQNKPYNN

QSDMWSLGCMIFEILCLKTAFQAKNINTLIMKIVSGKVPELPGIYSSKLRDICLNLLNQVPDQRMTAAQLCGHDLIAPFI
 ||.|||||   | . || .|.|.|  .|..||..| .| .|  || .|.     ...  |  |  . |.    |  |||
KSDIWSLGCVLYELCTLKHPFEANNWKNLVLKICQGTYPPIPPHYSYELQSLVSQMFKRNPRHRPSVNQI----LERPFI
Kinase GL50803_137719.AA Pkinase 4-259 30 9e-82 282.77 Pfam 1-293 (293) Show / Hide 
Range on Protein: 4-259
Range on HMM: 1-293/293
Sequence Identity: 30% (91 aa)

YTVIRKIGEGSFGECFLCCDKRTGLHVVIKEISMEDMQDTEVRNTER--ESAILLTMDHPNIVRGIESFKEDGFLYIAMTYCEHG----ELTSLIK-RHH
|...||||.||||....|..| ||  |..|.|. ..  . . ..  |  | .|.. ..|||||| ...| ... .|. | |||.|    .| ..|. . |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KSQMHFEESQVLRWIAQLASALWYIHSKGLIHRDLKSQNIFLDQDLNV----HIGDFGIART--INPGSMASTFIGSPLYMSPELIQ-GTSYNSQSDMWS
.. . |.| .. ... |....| |.||.| ||||||..||..|.. ..    .|.|||.|.   . ..| ..|| |.| ||.||.|. |. | . .||||
GCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGCMIFEILCLKTAFQAK------NINTLIMKIVSGKVPEL-PGIYS-------------------SKLRDICLNLLNQVPDQRMTAAQLCGHDLI
.||...| || .. |. .      . . .| .| ......  |  .|                   . ..|.. ..|.. | .| ||.|.. |. .
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase GL50803_137719.AA NEK4 4-263 40 3.1e-80 272.87 In-house 1-257 (257) Show / Hide 
Range on Protein: 4-263
Range on HMM: 1-257/257
Sequence Identity: 40% (106 aa)

YTVIRKIGEGSFGECFLCCDKRTGLHVVIKEISMEDMQDTEVRNTERESAILLTMDHPNIVRGIESFK-EDG-FLYIAMTYCEHGELTSLIKRHHKSQMH
|  .. .| ||.|| .|   .| .   |.| . .      | . .|.|  .|  . |||||   ||.. |.| |||| | .|| | |    |.  | |. 
YCHMKVVGKGSYGEVWLVRHRRDKKQYVMKKMFLKNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRKLKQ-QKNQF-

FEESQVLRWIAQLASALWYIHSKGLIHRDLKSQNIFLDQDLNVHIGDFGIARTIN-PGSMASTFIGSPLYMSPELIQGTSYNSQSDMWSLGCMIFEILCL
 ||.||. |  | | || |.| |  .||||| ||||| .   . ||||||.| .|  . ||.| || | |||||.     |.  ||.||||| ..|.  |
LEEYQVVEWFVQIAMALQYMHEKHILHRDLKTQNIFLTKKNIIKIGDFGISRVLNNHCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSLGCCVYEMITL

KTAFQAKNINTLIMKIVSGKVPELPGIYSSKLRDICLNLLNQVPDQRMTAAQLCGHDLIAPFI
| ||.||..| || .|. |. | .|  ||  | ..   .|.. |..|    ..    .  |.|
KHAFDAKDMNSLIYQIIQGQPPPMPPNYSQDLQNLVYQMLEKQPTKRPSIFDI----FQMPYI
Kinase GL50803_137719.AA STE 4-259 23 1.8e-67 230.5 In-house 1-359 (359) Show / Hide 
Range on Protein: 4-259
Range on HMM: 1-359/359
Sequence Identity: 23% (86 aa)

YTVIRKIGEGSFGECFLCCDKRTG-LH--------------VVIKEISMEDMQ---------------DTEVRNTERESAILLTMD--HPNIVRGIESFK
.. |.|||.|.||. ...... .. .|              . ||....|. .               ..|. . ..|  |.  ..  |||||. . .. 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EDG-------FLYIAMTYCEHGELTSLIKRHHKSQM----------HFEESQVLRWIAQLASA-LWYIHSKGLIHRDLKSQNIFLDQDLNVHIGDFGIAR
 .|        |.|.| |.. | |...||. .. ..          .|.|||. . . |.  . | |.||.. ||||.|..||.|     | . |||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

TINP-----------------GSMASTFIGSPLYMSPELIQG------TSYNSQSDMWSLGCMIFEILCLKTAF---QAKNINTLIM------------K
 ...                 ...  ||.|.| .|.|| ||.        |. ..|.|||||.| | .. |  .   .      .|.            .
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

IVSGKVPELPG-------------------IYSSKLRDICLNLLNQVPDQRMTAAQLCG--HDLI
|| |. | ||                     .|....|   . |.  |..| || ||    |  |
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase GL50803_137719.AA Ciliate-E2 4-259 21 1.6e-66 227.27 In-house 1-365 (365) Show / Hide 
Range on Protein: 4-259
Range on HMM: 1-365/365
Sequence Identity: 21% (80 aa)

YTVIRKIGEGSFGECFLCCDKRTGLH------------------VVIKEISMEDMQDTEVRNTERESAIL----------------LTMDHPNIVRGIES
| .|.|||.|.||  ..|......                    | ||.. |. |.  .......|  |.                 ...||||.. .|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FK--EDGFLYIAMTYCEHGELTSLIKRH-HKSQMHFE------ESQVLRWIAQLAS---------------ALWYIHSKG-LIHRDLKSQNIFLDQDLNV
|.   |  .|. | ||..|.| ..|| . .|.. ..|      | .... ..|...               || |.|||.  ||||.| .||..     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

HIGDFGIARTINPG--------------------------------SMASTFIGSPLYMSPELIQGTS---------YNSQSDMWSLGCMIFEILCLKTA
 | |||... ...                                  |. |..|.| ||.|| ..| .         |. ..|.||||....| |. |. 
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FQAKNINTLIMKIVSGKVPELP------------------GIYSSKLRDICLN----LLNQVPDQRMT-AAQLCGHDLI
|         ...   .  ..|                     | .  |.. .    .|.  |..|.| . |.  |  .
F---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase GL50803_137719.AA Ciliate-E2-Unclassified 4-259 23 7.7e-64 218.4 In-house 1-352 (352) Show / Hide 
Range on Protein: 4-259
Range on HMM: 1-352/352
Sequence Identity: 23% (82 aa)

YTVIRKIGEGSFGECFLCCDKRTGLHVVIKEIS---------MEDMQDTEVRNTERESA---------------ILLTMDHPNIVRGIESFKEDGFLYIA
|..|..||.|.||. ..| .| ...  ..|...         .. ..  .... ...                 ||| ..||.||. .. |. .  .|| 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MTYCEHGELTSLIK-------------RHHKSQMHFEESQVL-----RWIAQLASALWYIHSKG-LIHRDLKSQNIFLDQDL---NVHIGDFGIARTIN-
| |||.|.|   ||             .. |.. .|.| |..     ...||. ..| |.|.|.  ||||.| .||..|..    .. | ||||.. .. 
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

---------------PGSMASTFIGSPLYM----SPELIQGTSYNSQ----SDMWSLGCMIFEILCLKTAFQAKNINT----------------LIMKIV
               .  |..||.|.| ||    .||..||  |. .    .|.||||. ..|.|  .  |...| .                 |. .| 
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

SGKVPELP-------GIYSSKLRDICL----NLLNQVPDQRMTAAQLCGHDLI
 ...   .        . | .  |..      .|.  |..|.|. |.. | ..
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase GL50803_137719.AA ULK 4-259 22 1.6e-62 214.06 In-house 1-324 (324) Show / Hide 
Range on Protein: 4-259
Range on HMM: 1-324/324
Sequence Identity: 22% (72 aa)

YTVIRKIGEGSFG-ECFLCCDKRT---GLHVVIKEISMEDMQDTEVR--------NTERESAILLTMD---HPN--IVRGIESFKED--GFLYIAMTYCE
| .....|.||||   .   .|.|   . .| .| |..  |.. . .        . ..|  |. ...   |||  ||. .. |...   ..|| | ||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

HGELTSLIKRHHK-----SQMHFEESQVLRWIAQLASALWYIHSKGLIHRDLKSQNIFLDQDLN------------VHIGDFGIARTINPGSMASTFI--
.| | ..||...|      .  ..|....  . |..... ..|... ||||.| ||| .  .              . |.||| |.... ..|. . .  
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

--------GSPLYMSPELIQ----GTSYN-SQSDMWSLGCMIFEILCLKTAFQAKNINTLI-------------MKIVSGKVPELP-----GIYSSKLRD
        |.||||.|...|    .  |. . .|.|||||...|.|  |. |..  .|...             . ..  .  . |      . |....|
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

ICLNLLNQVPDQRMTAAQLCGHDLI
.   .|   ...|..  ..  | ..
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase GL50803_137719.AA NEK2 4-259 33 2.2e-60 202.03 In-house 1-319 (319) Show / Hide 
Range on Protein: 4-259
Range on HMM: 1-319/319
Sequence Identity: 33% (107 aa)

YTVIRKIGEGSFGECFLCCDKRTGLHVVIKEISMEDMQDTEVRNTERESAILLTMDHPNIVRGIESF--KEDGFLYIAMTYCEHGELTSLIKRHHKSQMH
| |   ||.|||| |    .| .|   | |||  . ||  |      |  ||    ||||||       ..   ||| | ||| | | ..||.  |    
YEVLYTIGNGSFGRCRKVRRKSDGKILVWKEICYGHMQEKECQMLVSECNILRQLKHPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIKKCRKERQY

FEESQVLRWIAQLASALWYIHS------------------KG---LIHRDLKSQNIFLDQDLN-------------------------------------
.||. ..|  .|| .||  .|                   .|    .|||.|  |||||.| |                                     
MEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHTILHRDIKPANIFLDYDHNDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQ

--VHIGDFGIARTIN-PGSMASTFIGSPLYMSPELIQGTSYNSQSDMWSLGCMIFEILCLKTAFQAKNINTLIMKIVSGKVPELPGIYSSKLRDICLNLL
  |  |||| ||  |   | | ||.| | |||||...| .||  || ||.||.|.|   |.  |||.|   |  ||  |.   .| .||. | .|    .
VVVKLGDFGLARMLNHDTSFAHTFVGTPYYMSPEQMHGQKYNEKSDIWSVGCLIYEMCALHPPFQATNQAQLQEKIKQGHFRRIPYQYSRHLNEIIHFMI

NQVPDQRMTAAQLCGHDLI
|  . .|     . .| .|
NVDHYHRPSIEEILQHPQI
Kinase GL50803_137719.AA ULK 4-259 23 2.5e-59 203.41 In-house 1-329 (329) Show / Hide 
Range on Protein: 4-259
Range on HMM: 1-329/329
Sequence Identity: 23% (76 aa)

YTVIRKIGEGSFGECFLCCDKRT----GLHVVIKEISMEDMQDTEVRN--------TERESAILLTMD--------HPNIVRGIESFKEDGF--LYIAMT
| .....|.||||  .   .|.|    .  |..| |. . |.  .  .         ..|  |. ...        |||||. .. |... .  .|| | 
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCEHGELTSLIKRHHK------SQMHFEESQVLRWIAQLASALWYIHSKGLIHRDLKSQNIFLDQDLN------------VHIGDFGIARTINPG----S
||..| | ..||...|       . ...|....  . |..... ..|... ||||.| ||| .. .              . |.||| |.... .     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

MASTFI------GSPLYMSPELIQ----GTSYN-SQSDMWSLGCMIFEILCLKTAFQAKNINTLI----MKIVSG----------KVPELP-----GIYS
|. |.       |.||||.|...|    .  |. . .|.|||||...|.|  |. |.|  .|...    .| .            . .. |      . |
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

SKLRDICLNLLNQVPDQRMTAAQLCGHDLI
....|.   .|   ...|..  .|  | ..
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase GL50803_137719.AA Pkinase_Tyr 4-155 30 3.3e-24 82.63 Pfam 1-161 (270) Show / Hide 
Range on Protein: 4-155
Range on HMM: 1-161/270
Sequence Identity: 30% (50 aa)

YTVIRKIGEGSFGECFLCCDK----RTGLHVVIKEISMEDMQDTE--VRNTERESAILLTM-DHPNIVRGIESFK-EDGF--LYIAMTYCEHGELTSLIK
 | ..|.|||.||| ...  |     |...| .| .  |.  . .   .   || .|. .. .|||||| .     ...   .|| | |..|| | .  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

RHHKSQMHFEESQVLRWIAQLASALWYIHSKGLIHRDLKSQNIFLDQDLNVHIGDFGIARTI
.|  .. ..  .. | . .| |... | .||..|||||   |. .. .. | |.||| ||.|
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI
Kinase GL50803_137719.AA TyrKc 4-259 23 1.9e-20 75.18 SMART 1-280 (280) Show / Hide 
Range on Protein: 4-259
Range on HMM: 1-280/280
Sequence Identity: 23% (69 aa)

YTVIRKIGEGSFGECFLCCDKRTGLHVVIKEISMEDMQDTEVRNTERESAILLTM--DHPNIVRGIESFKED-------GFLYIAMTYCEHGELTSLIKR
 | ..|.||| ||| ...  |   . | .| .  .      ..   ||  |.     .|||||| .    ..       . |.| | |..|| | . ...
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

HHKSQMHFEESQVLRWIAQLASALWYIHSKGLIHRDLKSQNIFLDQDLNVHIGDFGIARTINPG--------SMASTF-IGSP--L---YMSPELIQGTS
|..    .  .. | .  | |.   |.|||..|||||   |. .. .. | |.||| .| |  .           ..   |.   |    |.|| |.   
HRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YNSQSDMWSLGCMIFEILCL-KTAFQA-----KNINTLIMKIVSGKVPELPGI--------YSSKLRDICLNLLNQVPDQRMTAAQLCGHDLI
....|| || | ...||. . ..         ..   .| .. .|. .. |           .... .| .   .  |..| | ...  |...
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase GL50803_137719.AA Pkinase_Tyr 171-200 36 0.000232 15.39 Pfam 181-210 (270) Show / Hide 
Range on Protein: 171-200
Range on HMM: 181-210/270
Sequence Identity: 36% (11 aa)

MSPELIQGTSYNSQSDMWSLGCMIFEILCL
|.|| |.   ....|| || |  ..||. .
MAPECINYGKFTTKSDVWSFGVLMWEIFTY