Gene GL50803_13921 (G.lamblia)

GL50803_13921

Species: G.lamblia
Alias: GK251, GL50803_13921
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Nek
Subfamily: Nek-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_13921.AA Protein None 386 None Fasta, JSON
GL50803_13921.kin_dom Protein Kinase Domain None 266 None Fasta, JSON

Protein domain

Protein domains of GL50803_13921.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_13921.AA NEK 13-278 33 1.8e-86 293.59 In-house 1-286 (286) Show / Hide 
Range on Protein: 13-278
Range on HMM: 1-286/286
Sequence Identity: 33% (98 aa)

YRILQMAGQGAFGTVYKAEAVTTREL-----VAIKQLDYSDFSDSERDAMR-QELDVMPLLSHPHIVNYKAVVMDTRNQRAYIVMEFCE-GGELSEF---
|.|... |||.||.|||..   .        ...|. ...  |. |...   .|  .   | ||.|| |.   ..  |.. .||||.|| || |...   
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

IRMHKNKRTKIHEEIIWKFIAQLASALNYMHSP--FKKNSTVSGKIMHRDLKPQNIMLTKTGD----CKICDFNMCRSVQTA--RAKT-LAGTLAYLAPD
| ..|.|.. . ||.||.. .|...||.|||.           .||.|||.|||||.||| .      || ||.  .  ..    |.| . ||  |..| 
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGP------QRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPE

VCSNVGYTEKADMWSLGCIIYQMCEY--SLPFYWN--GIEDIHKDLKDI-QYKPISSD--YSNDMKGVVSSLLVLDPALRYSASDLLSHPRV
||.| .|..|.|.|||||..|.||      ||. .   ..   .  .   ||.||.|   ||.|.. ..|..|  || .|.|....|..| .
VCQNKPYNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase GL50803_13921.AA S_TKc 13-278 31 2.2e-78 267.66 SMART 1-231 (231) Show / Hide 
Range on Protein: 13-278
Range on HMM: 1-231/231
Sequence Identity: 31% (87 aa)

YRILQMAGQGAFGTVYKAEAVTTRELVAIKQLDYSDFSDSERDAMRQELDVMPLLSHPHIVNYKAVVMDTRNQRAYIVMEFCEG--GELSEFIRMHKNKR
|.||.  |.||||.|||.  . | ..||||...         . .|.|....    ||.||... |  |   .. |.|||.|.|  |.| ..|. .. ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

TK--IHEEIIWKFIAQLASALNYMHSPFKKNSTVSGKIMHRDLKPQNIMLTKTGDCKICDFNMCRSVQTARAKTLAGTLAYLAPDVCSNVGYTE-KADMW
..  ..|  ......|...||.|.|         | .|.||||||.||.|..    ||||| ..| .     .|. ||. |.|| |.   ||.  |.|.|
LRFPFPE-HARFYMYQICCALEYCH---------SHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWW

SLGCIIYQMCEYSLPFYWNGIEDIHKDLKDIQYKPISSDYSNDMKGVVSSLLVLDPALRYSASDLLS-------HPRV
|.|||.| |.    ||.   .. . | ..           | ..|  .. .|. ||. |..| ..|        || .
SCGCILYEMLCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase GL50803_13921.AA Pkinase 13-278 27 2e-75 261.72 Pfam 1-293 (293) Show / Hide 
Range on Protein: 13-278
Range on HMM: 1-293/293
Sequence Identity: 27% (86 aa)

YRILQMAGQGAFGTVYKAEAVTTRELVAIKQLDYSDFSDSERDAMRQ--ELDVMPLLSHPHIVNYKAVVMDTRNQRAYIVMEFCEGG----ELSEFIRMH
|.|..  |.|.||.|||.  . |...||.|...... ..... . |   |. .|  |.||.|| .. ...|  ... |.|||.||||    .|...|.  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST-

KNKRTKI--HEEIIWKFIAQLASALNYMHSPFKKNSTVSGKIMHRDLKPQNIMLTKTGDC----KICDFNMCR---SVQTARAKTLAGTLAYLAPDVCS-
  .....   |. . ... |....|.|.||          .|.||||||.||.. ..|..    |||||  ..         ..|..||. |.|| |.  
-WRHGCFYFSEWECKFYMYQILRGLEYCHSM---------GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRG

NVGYTEKADMWSLGCIIYQMCEYSLPFYWN----GIEDIHKDLKDIQYKPISSDYS-----------------------NDMKGVVSSLLVLDPALRYSA
. .|. |.||||.|||.|.|.   .||.      .  |  . .. | ..|...|..                        ..| .....| .||. |..|
GQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTA

SDLLSHPRV
 ..| || .
EQILQHPWF
Kinase GL50803_13921.AA Ciliate-E2 13-278 20 1.3e-62 213.79 In-house 1-365 (365) Show / Hide 
Range on Protein: 13-278
Range on HMM: 1-365/365
Sequence Identity: 20% (79 aa)

YRILQMAGQGAFGTVYKAEAVTTRE-----------------------LVAIKQLDYS--DFSDSERDAMR---------QELDVMPLLSHPHIVNYKAV
| .... |||.||.|||..   ...                       ..|.|..  .   .  .| . ||         .|. .. .|.||.|.... .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VMDTRNQRAYIVMEFCEGGELSEFIRMHKNKRTKI-------HEEIIWKFIAQLAS---------------ALNYMHSPFKKNSTVSGKIMHRDLKPQNI
  .. ..  |.|||.|.||.| ..|. .| ||...        |. | ....|...               ||.|.||         ..|.|||.||.||
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHS--------KNNIIHRDIKPENI

MLTKTGDCKICDFNMCRSVQT---------------------------------ARAKTLAGTLAYLAPDVCSNVG---------YTEKADMWSLGCIIY
..     .||.|| ... ...                                   ..|..||. |.|| . .. .         |..|.|.||||.|.|
LF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILY

QMCEYSLPFYWNGIEDIHKDLK-DIQYKPI---------------SSDYSNDMKGVVSS----LLVLDPALRYS-ASDLLSHPRV
.|.   .||       . . .. .|.. .                  . |...|   .     .|. ||  |.. ....| ||  
EMLFGKPPF-------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase GL50803_13921.AA ULK 13-278 24 1.4e-61 210.85 In-house 1-329 (329) Show / Hide 
Range on Protein: 13-278
Range on HMM: 1-329/329
Sequence Identity: 24% (83 aa)

YRILQMAGQGAFGTVYKAEAVTTR----ELVAIKQLDYSDFSDSERD--------AMRQELDVMPLLS--------HPHIVNYKAVVMDTRNQRAYIVME
| . .. |.|.||.|||.. . |     |.||.|..| . .. .. .          ..| ..|  |         ||.|| .. . ... .   ||.||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FCEGGELSEFIRMHKN------KRTKIHEEIIWKFIAQLASALNYMHSPFKKNSTVSGKIMHRDLKPQNIMLTKT------------GDCKICDFNMCRS
.|.|| |...|  .|.      .  .. |... .|. |..... ..|         . .|.|||.|||||....             | .||.||  ...
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELH---------KHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKH

VQTA-----RAKTLA------GTLAYLAPDVCS----NVGYT-EKADMWSLGCIIYQMCEYSLPFYWNGIEDIH-----KDLKD-------IQYKPISSD
|.        ..|        ||  | || . .    .  |.  |.|.||||||.|.|     |||.. ..|       | ...       |. .|.  .
VDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFP

-------YSNDMKGVVSSLLVLDPALRYSASDLLSHPRV
        |...|   . .|. |.  | |  .|..|| .
KDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase GL50803_13921.AA AGC 13-278 19 4.1e-60 153.11 In-house 1-395 (395) Show / Hide 
Range on Protein: 13-278
Range on HMM: 1-395/395
Sequence Identity: 19% (78 aa)

YRILQMAGQGAFGTVYKAEAV------TTRELVAIKQLDYSD--------FSDSERDA--------MRQELDVMPLLS----------HPHIVN-YKAVV
...| . |.|.||.|| .. .      .| .. |.| |. ..          .    .         ..| ... ...          || ||.  .   
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

MDTRNQRAYIVMEFCE--------GGELSEFIRMHKN-KRTKIHEEIIWKFIAQ-------LASALNYMHSPFKKNSTVSGKIMHRD-LKPQNIMLTKTG
 | ...  |.|||...        || .  |.....  |. .  || .  ..|.       ...|| |.||          .| ||| ||| ||.|.. |
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHS--------HMGIIHRDYLKPENILLDEDG

DCKICDFNMCRSVQT----------------------------------------------------ARAKTLAG--TLAYLAPDVCSNVGYTEKADMWS
 .|..|| .|  . .                                                    .|..|. |  |  |.|| .     |.  .| ||
HIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWS

--LGCIIYQMCEYSLPFYWNG----------IEDIHKDLK--------DIQYK-------PISSDYSNDMKGVVSSLLVLDPALRYS----------ASD
  |||..|.|     ||| .            .....  .        ....        |  .  |.. |  .. ||. ||. |            |..
FGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEE

LLSHPRV
. .||  
IKNHPWF
Kinase GL50803_13921.AA STE 13-278 22 4.2e-60 206.0 In-house 1-359 (359) Show / Hide 
Range on Protein: 13-278
Range on HMM: 1-359/359
Sequence Identity: 22% (84 aa)

YRILQMAGQGAFGTVYKAEAVT---------------TRELVAIKQLDYSDFS---------------DSERDAMRQELDVMPLLS--HPHIVNYKAVVM
...... |.|||||||||  .                | |..||||..... .               ..|..   .|...|  ..  ||.||.|    .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DTR-----NQRAYIVMEFCEGGELSEFIR-------MHKNKR---TKIHEEIIWKFIAQLASA-LNYMHSPFKKNSTVSGKIMHRDLKPQNIMLTKTGDC
.       ..  .|.||...|| |...|.       .....|   ... |..| ... |.  . |.| |         | .|.|||.||.||.|     .
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLH---------SHHIIHRDIKPANILL-----V

KICDFNMCRSVQT-----------------A-RAKTLAGTLAYLAPDVCSN------VGYTEKADMWSLGCIIYQMCEYSLPFYW-NGIEDIHKDLKDI-
|.|||  | ...                  . . .|..||  . || | ..       ||..|.|.||||| |  |..   |.   .  . .   .. . 
KLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYH

-------------QYKPISS-------------------DYSNDMKGVVSSLLVLDPALRYSASDLLS--HPRV
             .  |. .                    .| ..|  ..  |. ||  | .||.||.  || .
MQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase GL50803_13921.AA CAMK 20-278 20 1.6e-59 190.11 In-house 3-425 (425) Show / Hide 
Range on Protein: 20-278
Range on HMM: 3-425/425
Sequence Identity: 20% (89 aa)

GQGAFGTVYKAEAV-TTR-----------ELVAIKQLDYSDFS--------------------------DSERDAMRQELDVMPLLS-------HPHIVN
|.|.||.|....   ||.           . |||| .| .  .                          .. |. .|.|...| .|.       ||.|..
GRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIK

YKAVVMD-----------TRNQ-------RAYIVM---EFCEGGEL----SEFIRMHKNKR-----------TKIHEEIIWKFIAQLASALNYMHSPFKK
   |  |           | ..       . |.||   |.|.||||     ..|. |....            ...|.   ... |..||..|.||    
LYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHS----

NSTVSGKIMHRDLKPQNIMLTKT-----------------GDCKICDFNMCRSVQTAR-------------------------AKTLAGTLAYLA-PDVC
     . |.|||||| ||.|..                  .. ||.|| . . ..                             ||  ||..| | | | 
----HN-IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVL

SN--------------VGYTEKADMWSLGCIIYQMCEYSLPFYWN-------------GIEDIHKDLKDIQYK-P------------------ISSD---
.                .|..|.||||.|.| | |    .|||                ......  .  .|  |                  || .   
NGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH

-YSNDMKGVVSSLLVLDPALRYSASDLLSHPRV
  | . |  ....|. ||  |..... |.|| .
FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase GL50803_13921.AA ULK 13-278 24 1.8e-58 200.55 In-house 1-324 (324) Show / Hide 
Range on Protein: 13-278
Range on HMM: 1-324/324
Sequence Identity: 24% (81 aa)

YRILQMAGQGAFG-TVYKAEAVTT---RELVAIKQLDYSDFSDSERD--------AMRQELDVMPLLS---HPH--IVNYKAVVMDTRNQRAYIVMEFCE
| . .. |.|.|| .|||.. . |    ..||.|. | . ..... .          ..|  .|  |    ||.  || .. . ... .   ||.||.|.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGELSEFIRMHKN-----KRTKIHEEIIWKFIAQLASALNYMHSPFKKNSTVSGKIMHRDLKPQNIMLTKT------------GDCKICDFNMCRSVQT-
|| |...|  .|.     .  .. |... .|. |..... ..|         . .|.|||.|||||....             | .||.||  ...|.  
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELH---------KHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNN

----ARAKTLA------GTLAYLAPDVCS----NVGYT-EKADMWSLGCIIYQMCEYSLPFYWNGIED-I--HKDLKD--------IQYKPISSD-----
       .|.       ||  | || . .    .  |.  |.|.||||||.|.|   . ||... ..| .  ...|..        |...||  .     
NMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKD

--YSNDMKGVVSSLLVLDPALRYSASDLLSHPRV
   |...|   . .|. |.  | |  ....|| .
PKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase GL50803_13921.AA Ciliate-E2-Unclassified 13-278 23 7.6e-55 188.53 In-house 1-352 (352) Show / Hide 
Range on Protein: 13-278
Range on HMM: 1-352/352
Sequence Identity: 23% (85 aa)

YRILQMAGQGAFGTVYKAEAVTTRELV-----AIKQLDYS--DFSDSERDAMRQELDVM----------------PLLSHPHIVNYKAVVMDTRNQRAYI
|.|..  |||.||.|||..   .  ..     ..|. .|.      .. . |.... ..                .||.|||.. .| . ...  |  ||
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VMEFCEGGELSEFIR-------------MHKNKRTKIHEEIIW-----KFIAQLASALNYMHSPFKKNSTVSGKIMHRDLKPQNIMLTKTG---DCKICD
|||.||||.|...|.             .....| .. |. .      ...||. ..|.|.|.        ...| |||.||.||.... |    .||.|
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHH--------KNNIIHRDIKPENILFDNNGKNYYIKIID

FNMCRSVQ-----------------TARAKTLAGTLAYL----APDVCSNVGYT----EKADMWSLGCIIYQMCEYSLPFYWNGIED-------------
|  ..  |                   ...| .||. |.    || |  . .|     .|.|.||||.|.|.|.   .||| |  |.             
FGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAY

---IHKDLKD--IQYKPISS-----DYSNDMKGVVS----SLLVLDPALRYSASDLLSHPRV
   .... |.  ||... .      . |.  |  ..    ..|. .|  |......| ||  
RKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase GL50803_13921.AA NEK2 13-278 26 8.6e-50 165.79 In-house 1-319 (319) Show / Hide 
Range on Protein: 13-278
Range on HMM: 1-319/319
Sequence Identity: 26% (86 aa)

YRILQMAGQGAFGTVYKAEAVTTRELVAIKQLDYSDFSDSERDAMRQELDVMPLLSHPHIVNYKAVVMDTRNQRAYIVMEFCEGGELSEFIRMHKNKRTK
| .|.  |.| ||...|     . .. . | ..|      |...   |  .   | || || |   . |  |.. |||||.|||| ||  |   .. |. 
YEVLYTIGNGSFGRCRKVRRKSDGKILVWKEICYGHMQEKECQMLVSECNILRQLKHPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIKKCRKERQY

IHEEIIWKFIAQLASALNYMHS---------------PFKKNSTVSGKIMHRDLKPQNIMLTKTGD----------------------------------
. ||.||.  .|| .||   |                | ...  .   |.|||.|| || |   .                                   
MEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHT---ILHRDIKPANIFLDYDHNDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMD

-----CKICDFNMCRSVQ--TARAKTLAGTLAYLAPDVCSNVGYTEKADMWSLGCIIYQMCEYSLPFYWNGIEDIHKDLKDIQYKPISSDYSNDMKGVVS
      |  ||   |. .  |  |.|  ||  |  | . .   | || | ||.||.|| ||  . ||            |   . .| . || .   ...
YSQVVVKLGDFGLARMLNHDTSFAHTFVGTPYYMSPEQMHGQKYNEKSDIWSVGCLIYEMCALHPPFQATNQAQLQEKIKQGHFRRIPYQYSRHLNEIIH

SLLVLDPALRYSASDLLSHPRV
. . .|.  | |   .| ||..
FMINVDHYHRPSIEEILQHPQI
Kinase GL50803_13921.AA NEK1 13-278 30 9.7e-45 153.12 In-house 1-276 (276) Show / Hide 
Range on Protein: 13-278
Range on HMM: 1-276/276
Sequence Identity: 30% (86 aa)

YRILQMAGQGAFGTVYKAEAVTTRELVAIKQLDYSDFSDSERDAMRQELDVMPLLSHPHIVNYKAVVMDTRNQRAYIVMEFCEGGELSEFIRMHKNKRTK
| .... |.|.|| ....     . . .||    .  ...|| . . |  .   . || || ||       .   |||||.|.|| |   |   | |   
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGKL

IHEEIIWKFIAQLASALNYMHSPFKKNSTVSGKIMHRDLKPQNIMLT--KTG---------------DCKICDFNMCR--SVQTARAKTLAGTLAYLAPD
. |  |  .  |.  |||..|         . ||.|||.|.||| ||  | |                 |. ||   |  .  .. |.| .||  || | 
FSEDQIMHWFCQICLALNHIH---------DRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPE

VCSNVGYTEKADMWSLGCIIYQMCEYSLPFYWNGIEDIHKDLKDIQYKPISSDYSNDMKGVVSSLLVLDPALRYSASDLLSHPRV
 | | .|. | |.|||||. |  |  ..||  |             | ||.. ||.. .  ||...  .| .| |. ..|. | .
ICQNKPYNNKSDIWSLGCVLYELCTLKHPFEANNWKNLVLKICQGTYPPIPPHYSYELQSLVSQMFKRNPRHRPSVNQILERPFI
Kinase GL50803_13921.AA Pkinase_Tyr 13-210 27 6.5e-31 105.32 Pfam 1-201 (270) Show / Hide 
Range on Protein: 13-210
Range on HMM: 1-201/270
Sequence Identity: 27% (59 aa)

YRILQMAGQGAFGTVYKAEAV----TTRELVAIKQLDYSDFSDSE--RDAMRQELDVMPLL-SHPHIVNYKAVVM-DTR-NQRAYIVMEFCEGGELSEFI
 ..... |.||||.|||...      |.  ||.| |   . ....  |... .|. .|  | .||.||.. .|.. . . | . |||||....| | .. 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVMEYMPHGDLLDYL

RMHKNKRTKIHEEIIWKFIAQLASALNYMHSPFKKNSTVSGKIMHRDLKPQNIMLTKTGDCKICDFNMCRSV-----Q-TARAKTLAGTLAYLAPDVCSN
| |.. . ..  . . .. .| |....| .|   ||      . ||||   |...|... .||||| ..| .       ..| ..       .|| . ..
RKHREDKQPLTMKDLLQMCWQIAKGMEYLES---KN------CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINY

VGYTEKADMWSLG
  .|.| | || |
GKFTTKSDVWSFG
Kinase GL50803_13921.AA TyrKc 13-282 21 3.6e-23 84.2 SMART 1-280 (280) Show / Hide 
Range on Protein: 13-282
Range on HMM: 1-280/280
Sequence Identity: 21% (67 aa)

YRILQMAGQGAFGTVYKAEAVTTRELVAIKQLDYSDFSDSERDAMRQELDVMPLL--SHPHIVNYKAVVMDT-RN----QRAYIVMEFCEGGELSEFIRM
 . ... | ||||.|||...    . ||.| |  .      | ....|. .|  |  .||.||.  .|...  ||    .  .||||....| | ...| 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

HKNKRTKIHEEIIWKFIAQLASALNYMHSPFKKNSTVSGKIMHRDLKPQNIMLTKTGDCKICDFNMCRSVQTA----------RAKT--LA---GTLAYL
|..|   .  .   .|  | |.  .| ||          .. ||||   |..... . .||.|| ..| .             |.|.   .     .  .
HRPK---LCMKDLLSFCWQIACGMEYLHSK---------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM

APDVCSNVGYTEKADMWSLGCIIYQMCEYSLPFYWN------GIEDIHKDLKDIQYKPISSD--------YSNDMKGVVSSLLVLDPALRYSASDLLSHP
|| .     .|.| | || |  .. .. |  . |..        .......|.  . |.  .         . .|  . ..    ||. | . |..    
APECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI----

RVSRYL
   ...
--HECF