Gene GL50803_14172 (G.lamblia)

GL50803_14172

Species: G.lamblia
Alias: GK039, GL50803_14172
External Links: GiardiaDB ,
Annotation:

Classification

Group: CMGC
Family: RCK
Subfamily: MAK

Sequence

Name Sequence Type Origin Length Description Download
GL50803_14172.AA Protein None 302 None Fasta, JSON
GL50803_14172.kin_dom Protein Kinase Domain None 297 None Fasta, JSON

Protein domain

Protein domains of GL50803_14172.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc GL50803_14172.AA S_TKc 4-300 27 4.1e-88 299.96 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-300
Range on HMM: 1-231/231
Sequence Identity: 27% (86 aa)

YTPVRRVGSGTYGDVLHAVDTK-GDFVAIKIMNSHTLCVSDPLQLPEVATLRRLPPHPNIIRLIRVVVTRDHTHLIFEYAGG--GTLLNFLRSSGP----
|. .| .|.|..| |  ....| |  |||||..           . |.. |..   ||||..|. | .. || ....||..|  |.|. .... |.    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LKEHMLRNIAFRILQGLYHIHTNSVIHRDLKLENILLTSETGDANGDIVGVKIADFGLSRAQGSRQNTDYVSTRWYRAPELLLHYSGYGP-PIDIWAA
  . | . | ..  |...| ..| . .|||||| |||||..           .||.||||.|       | .. |.||.|||.|    |||. ..|.|. 
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----------HIKICDFGLARQL-----TTFCGTPWYMAPEVL----GYGKCKCDWWSC

GCCFAELLTGDPLFPGDTEIQQLQLICAFLKPLKPDACKGAMHALPRFITENMTVSDADIYTLAEAREALRRELGCSHVLADLLAHMLAWNPEDRITAQR
||...|.|.| |.||  .. . ...|.                                                 |. . |.. ..| ..||.|.||  
GCILYEMLCGYPPFP--QMQMMFKKIG-------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-E

ALM-------HQFF
||        |..|
ALQDEWDIKCHPWF
Pkinase GL50803_14172.AA Pkinase 4-300 27 2.4e-78 271.37 Pfam 1-293 (293) Show / Hide 
Range on Protein: 4-300
Range on HMM: 1-293/293
Sequence Identity: 27% (89 aa)

YTPVRRVGSGTYGDVLHAVDTKG-DFVAIKIMNSHTLCVSDPLQLP---EVATLRRLPPHPNIIRLIRVVVTRDHTHLIFEYAGGG----TLLNFLR--S
|. .|..|||..| | .... .  . ||.||.. ..   . . ..    |.. ..||  ||||.||.... ..|| ....||..||     |  ...  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

SGPL--KEHMLRNIAFRILQGLYHIHTNSVIHRDLKLENILLTSETGDANGDIVGVKIADFGLSR---AQGSRQNTDYVSTRWYRAPELLLHYSGYGPPI
.|..   |. .....  ||.||...| ...||||||.||||.  ..|. .     |||.||||..      .. .|... |.||.|||.......|||..
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDA---CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DIWAAGCCFAELLTGDPLFPGD----TEIQQLQLICAFLKPLKPDACKGA--------MHALPRFITENMTVSDADIYTLAEAREALRRELGCSHVLADL
|.|..|| ..|.|.| |.|||.    . . |.|.||  ..|  .  .           .|   .                   . . ..    |  . |.
DMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRH-W-H-------------------F-HWTF-HNWSEECKDF

LAHMLAWNPEDRITAQRALMHQFF
.  .|...|..|.||. .| | .|
IKWCLCKDPKKRPTAEQILQHPWF
Kinase GL50803_14172.AA CMGC 4-223 23 3e-77 253.2 In-house 1-370 (513) Show / Hide 
Range on Protein: 4-223
Range on HMM: 1-370/513
Sequence Identity: 23% (87 aa)

YTPVRRVGSGTYGDVLHAVDTK---------------GDFVAIKIMN---SHTLCV-------SDPLQLPEVATLRRL----------------PPHPNI
|. ....|.|||| |  ..|..               . .||||..     .. .             | |.  |..|                . |.||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

IRLIRVVVTRD-----------------HTHLIFEYAGGGTLLNFLRSSG---------PLKEHM------------LRNIA------FRILQGLY--HI
..|. ......                 | .|.||| .  .|......           ||.|               ...       . ||.||   ..
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDH-DLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HTNS--VIHRDLKLENILLTSET---------------GDANGDIVGVKIADFGLSRAQGSR-----------------------QNTDYVSTRWYRAPE
| .   .|||||| ||||.....                    .   .||.||||.|. ...                       ..|.||.||||||||
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPC---QKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPE

LLLHY---------SGYGPPIDIWAAGCCFAELLTG--------DPLFPGDTE-----------IQQLQLICAFL
.|| .          .|..|||.|..|| |||..||        .|||||..|           | ||..|.  |
ILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVL
Kinase GL50803_14172.AA RCK 4-220 42 5.8e-69 217.86 In-house 1-227 (298) Show / Hide 
Range on Protein: 4-220
Range on HMM: 1-227/298
Sequence Identity: 42% (98 aa)

YTPVRRVGSGTYGDVLHAVDTK-GDFVAIKIMNSHTLCVSDPLQLPEVATLRRLPPHPNIIRLIRVVVTRD--HTHLIFEYAGGGTLLNFLRS---SGP-
|. ....| ||||.|. |.... |..|||| |  .     .  .|.|.  ||.|.|||||| |. |.  .|  . ...|||     |  ....   ..  
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMKQKFYSWEECMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMDMN-LYQMMKDFKERRKY

LKEHM--LRNIAFRILQGLYHIHTNSVIHRDLKLENILLTSE---TGDANGDIVGVKIADFGLSRAQGSRQ-NTDYVSTRWYRAPELLLHYSGYGPPIDI
| |    ..|| . ||||| |.|..   ||||| |||..|..     | . |.  .|||||||.|   |.. .|||||||||||||.||.   |  |.||
LPENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDH--IKIADFGLCREIRSKPPYTDYVSTRWYRAPECLLRCTYYNSPMDI

WAAGCCFAELLTGDPLFPGDTEIQQLQLIC
|| || ..|| .  |||||  || |.. ||
WAVGCIMYELYMLRPLFPGSSEIDQIFKIC
Kinase GL50803_14172.AA MAK 4-223 35 1.2e-61 194.81 In-house 1-264 (352) Show / Hide 
Range on Protein: 4-223
Range on HMM: 1-264/352
Sequence Identity: 35% (96 aa)

YTPVRRVGSGTYGDVLHAVD-------------------------------TKGDFVAIKIMNSHTLCVSDPLQLPEVATLRRLPPHPNIIRLIRVVV--
|. ....| ||||.|. | .                                 |. |||| |        . ..| ||  |. |. ||||..|  |.   
YQMIKQLGDGTYGCVMLAKRQFPLSNILGKQHDIRGTLMDQPKNGHQNYIIDTGEKVAIKRMKKKFYSWEECMNLREVKSLKKLNAHPNIVKLKEVIRDS

TRDHTHLIFEYAGGGTLLNFLRSSGP--LKEHMLRNIAFRILQGLYHIHTNSVIHRDLKLENILLTSE-----------TGDANGDIVGVKIADFGLSRA
 .|| ...|||     |   .       . |  .||| . ||||| ..|..   |||.| |||...              |  . ..  .||||||| | 
ENDHLYFVFEYM-KENLYQMMKDRDRRHFPEPVIRNIMYQILQGLAFMHKHGFFHRDMKPENIMCMGPTQYFEKEYMNQIGYQDNEL--IKIADFGLARE

QGSRQ-NTDYVSTRWYRAPELLLHYSGYGPPIDIWAAGCCFAELLTGDPLFPGDTEIQQLQLICAFL
  |.   ||||||||||||| ||. . |. |||.|| ||  ||| |  |||||  || |.  ||  |
IRSKPPYTDYVSTRWYRAPEVLLRSTYYSSPIDMWAVGCIMAELYTFRPLFPGSSEIDQIFKICQVL
Kinase GL50803_14172.AA CDK 49-223 38 5.3e-59 187.34 In-house 58-241 (284) Show / Hide 
Range on Protein: 49-223
Range on HMM: 58-241/284
Sequence Identity: 38% (78 aa)

EVATLRRLPPHPNIIRLIRVVVTR-----------DHTHLIFEYAGGGTLLNFLRSSGPLKEHMLRNIAFRILQGLYHIHTNSVIHRDLKLENILLTSET
|...|. |  ||||..|. |..|                ..|||.    |  ...          ... . .|.||...| | ..|||||  |||...  
EISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEYMDH-DLKKYMD---------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINN--

GDANGDIV--GVKIADFGLSRAQGS--------RQNTDYVSTRWYRAPELLL---HYSGYGPPIDIWAAGCCFAELLT---GDPLFPGDTEIQQLQLICA
   ||  .   .|||||||.|| |.        |  |  | |.|||||||||   |||| |.|||.|..|| |||..|   . ||||||.|| || .|. 
---NGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELLLGSKHYSG-GTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFR

FL
..
IC
Kinase GL50803_14172.AA CDKL 59-229 43 3.9e-49 166.13 In-house 57-222 (286) Show / Hide 
Range on Protein: 59-229
Range on HMM: 57-222/286
Sequence Identity: 43% (76 aa)

HPNIIRLIRVVVTRDHTHLIFEYAGGGTLLNFLRSSGP--LKEHMLRNIAFRILQGLYHIHTNSVIHRDLKLENILLTSETGDANGDIVGVKIADFGLSR
|.||  || |   .   || |||    |.|. |    |  . || .|.. . ||... . | . .|||| | ||||.|   |        ||. |||. |
HENIVNLIEVFRRKRKLHLVFEYC-DHTVLHELEE-YPNGVDEHVVRKYMWQILKAINFCHKHNCIHRDIKPENILITPKNGQ-------VKLCDFGFAR

AQGSRQN---TDYVSTRWYRAPELLLHYSGYGPPIDIWAAGCCFAELLTGDPLFPGDTEIQQLQLICAFLKPLKPD
 . . ..   |||| ||||||||||. .  ||.|.||||.|| .||...| ||.||. .| || .|   | || |.
-MLAKPGEIYTDYVATRWYRAPELLVGDTQYGKPVDIWAIGCVMAEMIDGQPLWPGQSDIDQLYHIQKCLGPLIPR
Kinase GL50803_14172.AA CDC2 49-216 39 2.3e-48 146.46 In-house 50-218 (301) Show / Hide 
Range on Protein: 49-216
Range on HMM: 50-218/301
Sequence Identity: 39% (70 aa)

EVATLRRLPPHPNIIRLIRVVVTRDHTHLIFEYAGGGTLLNFLR-SSG---PLKEHMLRNIAFRILQGLYHIHTNSVIHRDLKLENILLTSETGDANGDI
|  .|  | .||||..|  |..      ..|||     | .... | .   .. .. ...... ||||. . |.. ..|||||  |||.     |..|. 
EISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYL-DMDLKKYMDMSIPKNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILI-----DKKGN-

VGVKIADFGLSRAQG--SRQNT--DYVSTRWYRAPELLLHYSGYGPPIDIWAAGCCFAEL---LTGDPLFPGDTEIQQL
  .|||||||.|| |  .|. |    | |.||||||.||  . |  |.|.|. || |||.    |  |||.|| || ||
--IKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEMFMDVTKKPLFHGDSEIDQL
Kinase GL50803_14172.AA MAPK 87-223 37 1.2e-45 155.78 In-house 102-251 (328) Show / Hide 
Range on Protein: 87-223
Range on HMM: 102-251/328
Sequence Identity: 37% (60 aa)

LLNFLRSSGPLKEHMLRNIAFRILQG--LYHIHTNSVIHRDLKLENILLTSETGDANGDIVGVKIADFGLSRAQGSRQN----------------TDYVS
| . ..|  || ..  . . . || |  | .||   ||||||| .|||.... .|        ||.||||.|   . ..                |.||.
LHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNEN-CDL-------KICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVA

TRWYRAPELLLH--YSGYGPPIDIWAAGCCFAELLT-GDPLFPGDTEIQQLQLICAFL
||||||||..|   . .|   .|.|..|| |||.|| . |||||.  | |..|| ..|
TRWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVL
Kinase GL50803_14172.AA STE 4-219 21 1.6e-43 150.88 In-house 1-280 (359) Show / Hide 
Range on Protein: 4-219
Range on HMM: 1-280/359
Sequence Identity: 21% (65 aa)

YTPVRRVGSGTYGDVLHAVDTK----------------GDFVAIKIMN-----------SHTLCV-------SDPLQLPEVATLRRLPP-HPNIIRLIRV
.. ....|.|..| |  |.. |                |...|||.||                .            | |. ..... . ||||.. .  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQEN-Q-ELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGC

VVT-------RDHTHLIFEYAGGGTLLNFLR-SSGPLK-------------EHMLRNIAFRILQG-LYHIHTNSVIHRDLKLENILLTSETGDANGDIVG
 .        .|. ... || .||.|  ...   |..|             |. .. |.. ||.| ||..| . .||||.|  ||||             
YFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-------------

VKIADFGLSR-------------------AQGSRQNTDYVSTRWYRAPELLLH-----YSGYGPPIDIWAAGCCFAELLTGDPLFPGDTEIQQLQLI
||..|||..                     .... ||.  .   . ||| ..       .||.   |||  ||.  |..|| | .   .  . . .|
VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP--WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMI
Kinase GL50803_14172.AA Ciliate-E2 4-222 20 4.1e-41 138.85 In-house 1-307 (365) Show / Hide 
Range on Protein: 4-222
Range on HMM: 1-307/365
Sequence Identity: 20% (66 aa)

YTPVRRVGSGTYGDVLHA-VDTKGDFVAIKIMNSHTLCVSD---------------------PLQLPEVATLRRLPP---------------HPNIIRLI
|  ..  |.|..|.|  . |. ..  .|||| . . . ..                        .. |   .|.. .               |||||...
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQ-QRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMY

RVVV--TRDHTHLIFEYAGGGTLLNFLRSS-----------GPLKEHMLRNIAFRILQ---------------GLYHIHTNS-VIHRDLKLENILLTSET
 .    ....  |..||. ||.|. .....           ....|   ..|   |||               .| ..| .  .||||.|.||||.    
ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

GDANGDIVGVKIADFGLSRAQGSR----------QNTDYVS------------------------TRWYRAPELLL--HYSG------YGPPIDIWAAGC
         .||.|||||. .             ..  . .                        |  | ||| |    |..      |.  .|||..|.
---------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGV

CFAELLTGDPLFPGDTEIQQLQLICAF
.. |.|.| | |    ..|..|  . |
ILYEMLFGKPPF----QQQIKQCKIDF
Kinase GL50803_14172.AA ERK 109-219 45 1.9e-37 130.71 In-house 117-229 (307) Show / Hide 
Range on Protein: 109-219
Range on HMM: 117-229/307
Sequence Identity: 45% (55 aa)

ILQGLYHIHTNSVIHRDLKLENILLTSETGDANGDIVGVKIADFGLSR----AQGSR------QNTDYVSTRWYRAPELLLHYSGYGPPIDIWAAGCCFA
|| || .||   |||||||  |||..|     |.|    ||.||||.|     . ..      . |.||.||||||||..| .. |  ..|||..|| ||
ILCGLKYIHSANVIHRDLKPSNILVNS-----NCDL---KICDFGLARCFDASYQENHECNQNFMTEYVATRWYRAPEIMLSWQKYTKAMDIWSCGCIFA

ELLTGDPLFPGDTEIQQLQLI
|.| ..|||||   . |...|
EMLGRKPLFPGKDYVHQINRI
Kinase GL50803_14172.AA Pkinase_Tyr 4-181 25 2.1e-21 73.13 Pfam 1-189 (270) Show / Hide 
Range on Protein: 4-181
Range on HMM: 1-189/270
Sequence Identity: 25% (50 aa)

YTPVRRVGSGTYGDVLHAVDT-----KGDFVAIKIMNSHTLCV---SDPLQLPEVATLRRLPPHPNIIRLIRVVV-TRDH--THLIFEYAGGGTLLNFLR
 |  .  |.| .|.| ... .     ..  ||.|... ..      .. .   |..... |. ||||.||. |..  ...    ...||. .| ||..||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

S----SGPLKEHMLRNIAFRILQGLYHIHTNSVIHRDLKLENILLTSETGDANGDIVGVKIADFGLSRAQ-------GSRQNTDYVSTRWYRAPELLLHY
.     .||. ..| .... | .|. . . .  |||||   |.|.|.       .   |||.||||.|.         .|.... .  .|. ||| . ..
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE-------NN-VVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWM-APECINYG
Kinase GL50803_14172.AA TyrKc 4-300 21 1.3e-15 29.62 SMART 1-280 (280) Show / Hide 
Range on Protein: 4-300
Range on HMM: 1-280/280
Sequence Identity: 21% (71 aa)

YTPVRRVGSGTYGDVLHAVDTKGDFVAIKIMNSHTLCVSDPLQLPEVATLRRL-PPHPNIIRLIRVVVTR-------DHTHLIFEYAGGGTLLNFLRSSG
 |  .  |.| .| | ... .    ||.| .....  . | ..  |   ...| . ||||.||. |...        .   ...||. .| |...||...
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMR--EARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

P-LKEHMLRNIAFRILQGLYHIHTNSVIHRDLKLENILLTSETGDANGDIVGVKIADFGLSRAQGSR----QNTDYVS------TR------WYRAPELL
| |.   | .... | .|  ..| . .|||||   |.|....          |||.||||||. ..      ..|| .      ..      |. ||| .
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI

LHYSGYGPPIDIWAAGCCFAELLT-GDPLFPG-----DTEIQQLQLICAFLKPLKPDA----CKGAMHALPRFITENMTVSDADIYTLAEAREALRRELG
  |. . .  |.|. | |  |..| |..  ||      . .. .... .   . .|.                                          .
-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-------------------------------F---VC

CSHVLADLLAHMLAWNPEDRITAQRALMHQFF
|.  . ..     . .|||| | .    |..|
CPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase GL50803_14172.AA RCK 275-300 53 2.1e-12 35.35 In-house 273-298 (298) Show / Hide 
Range on Protein: 275-300
Range on HMM: 273-298/298
Sequence Identity: 53% (14 aa)

DLLAHMLAWNPEDRITAQRALMHQFF
.|.  ||.|.|. ||||| || |..|
ELMEKMLQWDPQKRITAQQALQHPYF
Kinase GL50803_14172.AA CMGC 266-300 42 1.4e-11 33.41 In-house 479-513 (513) Show / Hide 
Range on Protein: 266-300
Range on HMM: 479-513/513
Sequence Identity: 42% (15 aa)

ELGCSHVLADLLAHMLAWNPEDRITAQRALMHQFF
.. |.. . |||  || ..|..||||. || | .|
RKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase GL50803_14172.AA CDC2 275-300 50 7.8e-11 28.99 In-house 276-301 (301) Show / Hide 
Range on Protein: 275-300
Range on HMM: 276-301/301
Sequence Identity: 50% (13 aa)

DLLAHMLAWNPEDRITAQRALMHQFF
|||  ||. .|..||.|..|| | .|
DLLMQMLQYDPQKRISAKEALQHPYF
Kinase GL50803_14172.AA CDK 275-300 50 2.2e-10 29.29 In-house 259-284 (284) Show / Hide 
Range on Protein: 275-300
Range on HMM: 259-284/284
Sequence Identity: 50% (13 aa)

DLLAHMLAWNPEDRITAQRALMHQFF
||| .||. .|. ||.|. || |..|
DLLNKMLCYDPKKRISAEQALQHPYF
Kinase GL50803_14172.AA MAPK 268-300 39 3.3e-09 27.74 In-house 296-328 (328) Show / Hide 
Range on Protein: 268-300
Range on HMM: 296-328/328
Sequence Identity: 39% (13 aa)

GCSHVLADLLAHMLAWNPEDRITAQRALMHQFF
....   |||  ||...|..|||.. || | .|
NANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase GL50803_14172.AA MAK 269-300 36 4.2e-09 24.66 In-house 320-352 (352) Show / Hide 
Range on Protein: 269-300
Range on HMM: 320-352/352
Sequence Identity: 36% (12 aa)

CSH-VLADLLAHMLAWNPEDRITAQRALMHQFF
||   . .|.  ||.|.|. | ||| .. . .|
CSQSDAIELMKDMLQWDPNKRPTAQQCCKYPYF
Kinase GL50803_14172.AA ERK 269-300 40 5.4e-08 26.07 In-house 276-307 (307) Show / Hide 
Range on Protein: 269-300
Range on HMM: 276-307/307
Sequence Identity: 40% (13 aa)

CSHVLADLLAHMLAWNPEDRITAQRALMHQFF
|..   |||  ||...|..|||.  .| | .|
CNPQAIDLLEKMLVFDPDKRITVEECLEHPYF
Kinase GL50803_14172.AA MAPK 4-32 36 6.9e-08 23.12 In-house 1-36 (328) Show / Hide 
Range on Protein: 4-32
Range on HMM: 1-36/328
Sequence Identity: 36% (13 aa)

YTPVRRVGSGTYGDVLHAVDTK-------GDFVAIK
|......|.| || |  |.|..       |..||||
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIK
Kinase GL50803_14172.AA CDKL 264-300 23 1.6e-07 21.82 In-house 249-286 (286) Show / Hide 
Range on Protein: 264-300
Range on HMM: 249-286/286
Sequence Identity: 23% (9 aa)

RRELGCS-HVLADLLAHMLAWNPEDRITAQRALMHQFF
.| .. |  ...|..  .|  .| .|.|.. .. | .|
KRYPNKSNKKALDFMKKCLHMDPDERMTCEQLMHHPYF
Kinase GL50803_14172.AA Ciliate-E2 275-300 38 5.5e-07 19.99 In-house 335-365 (365) Show / Hide 
Range on Protein: 275-300
Range on HMM: 335-365/365
Sequence Identity: 38% (12 aa)

DLLAH----MLAWNPEDRIT-AQRALMHQFF
||.      ||  .|| ||| .. .| |..|
DLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase GL50803_14172.AA CDK 4-32 37 8.6e-07 17.58 In-house 1-35 (284) Show / Hide 
Range on Protein: 4-32
Range on HMM: 1-35/284
Sequence Identity: 37% (13 aa)

YTPVRRVGSGTYGDVLHAVDTK-G-----DFVAIK
|  . ..| |||| |  | |.. |     ..||.|
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALK
Kinase GL50803_14172.AA CDC2 4-32 36 0.000103 9.83 In-house 1-30 (301) Show / Hide 
Range on Protein: 4-32
Range on HMM: 1-30/301
Sequence Identity: 36% (11 aa)

YTPVRRVGSGTYGDVLHAVDTK-GDFVAIK
|. ....| |||| |  . |.. .. ||.|
YQKIEKIGEGTYGVVYKCKDMQTNQIVALK
Kinase GL50803_14172.AA ERK 4-32 37 0.000142 13.17 In-house 1-35 (307) Show / Hide 
Range on Protein: 4-32
Range on HMM: 1-35/307
Sequence Identity: 37% (13 aa)

YTPVRRVGSGTYGDVLHAVDTK------GDFVAIK
|  . ..| |.|| |  |.|..      |..||||
YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIK
Kinase GL50803_14172.AA STE 269-300 29 0.002207 7.95 In-house 326-359 (359) Show / Hide 
Range on Protein: 269-300
Range on HMM: 326-359/359
Sequence Identity: 29% (10 aa)

CSHVLADLLAHMLAWNPEDRITAQRALM--HQFF
.|  . | ... |  .|..| ||.  |   | |.
WSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI