Gene GL50803_1656 (G.lamblia)

GL50803_1656

Species: G.lamblia
Alias: GL50803_1656, GK078
External Links: GiardiaDB ,
Annotation:

Classification

Group: STE
Family: STE11
Subfamily: STE11-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_1656.AA Protein None 486 None Fasta, JSON
GL50803_1656.kin_dom Protein Kinase Domain None 284 None Fasta, JSON

Protein domain

Protein domains of GL50803_1656.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc GL50803_1656.AA S_TKc 82-365 28 4.1e-90 306.59 SMART 1-231 (231) Show / Hide 
Range on Protein: 82-365
Range on HMM: 1-231/231
Sequence Identity: 28% (85 aa)

YSLGRIIGHGSFGQVYLALEHLTGKLLAVKEMVVKNCSREVLEAIDAETRILINLRHPNIVNIYDIEVSDDGNKLLIVMDFIAG--GSLASLSKSFKG--
| ..|.||.|.||.||.. .. ||.. |.|..          | |  | .|| . .|||||..||. ..   ..| .||... |  |.| .. |. ..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----IPEILCRRYARQILEAIKHMHRQNVAHLDLKCSNIMIGGDGLVKLVDFGTATRLARDDIINELQRRKETEADPKKPGLPSEAAKKFNLGIKGSPYW
    .||  .|.|..||..|....|.... | ||| .||..     .|. ||| |..|                                   . |.|..
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------------------------------TTFCGTPWY

IAPECVRSTLYDIFKADIWSIGCLFIEMFTTYPPFFQFKQVPALLYHIATITEPPGLPETMSDEGRDFLSKCLQINPEARASVDDLLA-------HPWV
.||| .    |. .|.|.||.||...||.. ||||      .......             |.|..||..|||| .|| | .. ..|.       |||.
MAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase GL50803_1656.AA STE11-Unclassified 82-365 29 9.5e-87 294.51 In-house 1-308 (308) Show / Hide 
Range on Protein: 82-365
Range on HMM: 1-308/308
Sequence Identity: 29% (95 aa)

YSLGRIIGHGSFGQVYLALEHLTGKLLAVKEMVVKNCS------REV-LEAIDAETRILINLRHPNIVNIYDIEVSDDGNKLLIVMDFIAGGSLASLSKS
.  | .|| |||||||....  ||...|||.. ... .       .. ...|  | ..| .|.|.|||. |..|........ |.|  ..|||..|. . 
WQKGEFIGKGSFGQVYKCMNCNTGEFMAVKQIEIHDYNSQQEDMQKEMIQSIQKEMKVLKQLNHKNIVQYYGCEIHKHEDCINIFMEYMPGGSIWSMLNK

FKGIPEILCRRYARQILEAIKHMHRQNVAHLDLKCSNIMIGGDGLVKLVDFGTAT-------RLARDDIINELQRRKETEADPKKPGLPSEAAKKFNLGI
.    | . . |..|||| ..  | ... | |.|  || |..|| .||.|||.|        |..|   |..            |  ....  ....  .
YGCFDEMVIKKYTKQILEGLAYLHSHGIIHRDIKGANILIDFDGICKLTDFGCAKQIEFDRTRTVRMNKIQNFD--------HYKICQHINSQQNHCKSM

KGSPY---WIAPECVR---STLYDIFKADIWSIGCLFIEMFTTYPPFFQFKQ--VPALLYHIATITEPPGLPETMS-----------DEGRDFLSKCLQI
.|.||   | ||| ..   .| ..  |.||||.||. |||.|  .|.  ...   ......|.   ..| .||..|           .|..|||.||.||
QGTPYQPFWMAPEVIKNSTQTGHCR-KSDIWSLGCTVIEMATGKHPWSNCQNDNFMWAIMKIVMSNQIPQIPEHLSPVCDFISCWISQECKDFLRKCFQI

NPEARASVDDLLAHPWV
.|. |.... || ||. 
DPKKRPTANQLLQHPFI
Kinase GL50803_1656.AA STE11 82-365 30 1.6e-83 283.77 In-house 1-303 (303) Show / Hide 
Range on Protein: 82-365
Range on HMM: 1-303/303
Sequence Identity: 30% (98 aa)

YSLGRIIGHGSFGQVYLALEHLTGKLLAVKEMVVKNCS------------REVLEAIDAETRILINLRHPNIVNIYDIEVSD-DGNKLLIVMDFIAGGSL
. .| ||| |.||.||...   ||.|.|||.. ..| .            . ...||  | ... .|.|.|||  |.....| . ... | | ...||||
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSL

ASLSK-SFKG--IPEILCRRYARQILEAIKHMHRQNVAHLDLKCSNIMIGGDGL-VKLVDFGTATRLARDDIINELQRRKETEADPKKPGLPSEAAKKFN
.|. .  .     .| . |.| .||||...  | ... | |.|  ||..  ||  .||.|||.|.||| .   .. ..  .                  .
SSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQN-H---------------C

LGIKGSPY--------WIAPECVRSTL---YDIFKADIWSIGCLFIEMFTTYPPFFQFKQ-VPALLYHIATI-TEPPGLPETMS------DEGRDFLSKC
  ..|.||        | ||| .. .    |.  ||||||.||  |||.|. ||.  ...   | ...|..  . .| .|| ||      .|.||||..|
KSMTGTPYNSMMGTPMWMAPEVIKQEGRDGYGR-KADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHC

LQINPEARASVDDLLAHPWV
....|. |.....|| ||..
FEHDPKKRPTANQLLQHPFI
Kinase GL50803_1656.AA STE 82-365 24 2.6e-82 279.75 In-house 1-359 (359) Show / Hide 
Range on Protein: 82-365
Range on HMM: 1-359/359
Sequence Identity: 24% (95 aa)

YSLGRIIGHGSFGQVYLALEHL---------------TGKLLAVKEMVVKNCS---------------REVLEAIDAETRILINLR--HPNIVNIYDIEV
. . ..||.|.||.||.|. |                ||.. |.|.| ..||.                | .. |  | .|. ...  |||||. |. ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

SDD-----GNKLLIVMDFIAGGSLASLSK---SFKG-----------IPEILCRRYARQILEA-IKHMHRQNVAHLDLKCSNIMIGGDGLVKLVDFGTAT
 ..     ...| |.| ...|||| .. |   . ..           .|| . ....||||..  .. |.... | |.|..||..     |||.|||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

RLARD----------DIINELQRRKETEADPKKPGLPSEAAKKFNLGIKGSPYWIAPECVRS------TLYDIFKADIWSIGCLFIEMFTTYPPFFQFKQ
.|. .          |  .                  .|  .. .  . |.| | ||| ..         ||. |.||||.||. ||| |  ||.. .. 
QLTDSMANIQSNNIID--C------------------IETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDT-KCDIWSLGCTIIEMATGKPPWHDMHP

VPALLYHIATI-------------TEPPGLPE-------------------TMSDEGRDFLSKCLQINPEARASVDDLLA--HPWV
  |... .  .              .|| ||.                    .|.| .||..||||..|. |.....||   ||..
MRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase GL50803_1656.AA Pkinase 82-365 26 5.2e-66 230.4 Pfam 1-293 (293) Show / Hide 
Range on Protein: 82-365
Range on HMM: 1-293/293
Sequence Identity: 26% (84 aa)

YSLGRIIGHGSFGQVYLALEHLTGKLLAVKEMVVKNCSREVLEAIDA--ETRILINLRHPNIVNIYDIEVSDDGNKLLIVMDFIAGG----SLA-----S
| .||.|| ||||.||.. .. |||. |||.. ... . .....     | .|. .|.||||| .||.  .  .... .||..  ||    .|.     .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTW

LSKSFKGIPEILCRRYARQILEAIKHMHRQNVAHLDLKCSNIMIGGDGLV----KLVDFGTATRLARDDIINELQRRKETEADPKKPGLPSEAAKKFNLG
 ...|   .|  |..|..|||......|.... | ||| .||.|  .| .    |. ||| |  .                          .  .  . .
RHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-------------------------Y-NNS-MTT

IKGSPYWIAPECVRSTLYDIFKADIWSIGCLFIEMFTTYPPFFQF-----KQVPALLYHIAT--ITEPPGLPETMS-----------------DEGRDFL
. |.|...||| .|.  |.  |.|.||.||...||.. .||| .          .... |    . ..   . ..|                 .|..||.
FCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFI

SKCLQINPEARASVDDLLAHPWV
..||. .|. | . ...| |||.
KWCLCKDPKKRPTAEQILQHPWF
Kinase GL50803_1656.AA CAMK 87-365 17 4.9e-64 204.96 In-house 1-425 (425) Show / Hide 
Range on Protein: 87-365
Range on HMM: 1-425/425
Sequence Identity: 17% (79 aa)

IIGHGSFGQVYLALEHLTG------------KLLAVKEMVVKNCS--------------------------REVLEAIDAETRILIN-------LRHPNI
..|.||||.|.|. . .|.            .  |.| .  |  .                           . .. .  | .|. .       |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VNIYD-----------IEVSDDGNK--------LLIVM---DFIAGG----SLASLSKSFKG---------------IPEILCRRYARQILEAIKHMHRQ
...|.           .. ..  .|        . .||   ... ||     | .  .. ..               ..|  .||| |||..|....| .
IKLYEVYEDPHYFKNTND-YET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSH

NVAHLDLKCSNIMIGGD-----------------GLVKLVDFGTATRLARDDIINELQRRKETEADPKKPGLPSEAAKKFNLG------------IKGSP
|..|.|||. ||..  .                 . .|..||| |... ...  . ..  |. |   ..                            |.|
NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HN-------------QWTTPTEGQKMKTFCGTP

YWIA-PECVRS-------------TLYDIFKADIWSIGCLFIEMFTTYPPFFQFKQ-----------VPALLYHIATITEPPGLPETMSD----------
. .| || ...               |. .|.|.||.|..   | . ||||   ..            .  |..  .  .    |. .|.          
EYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWW

-------------EGRDFLSKCLQINPEARASVDDLLAHPWV
             | .|...|.|| .|| |..... |.|||.
DDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase GL50803_1656.AA Ciliate-E2-Unclassified 82-365 20 2.5e-52 179.82 In-house 1-352 (352) Show / Hide 
Range on Protein: 82-365
Range on HMM: 1-352/352
Sequence Identity: 20% (74 aa)

YSLGRIIGHGSFGQVYLALEHLTGKLL-------AVKEMVVKNCSREVLEAIDAETRILIN----------------LRHPNIVNIYDIEVSDDGNKLLI
| ....||.|.||.||.. .  .. ..        ...  .|.  ..  | .  .... ..                | ||... ......  | ... |
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VMDFIAGGSLASLSKSFKG-----------------IPEILCR-----RYARQILEAIKHMHRQN-VAHLDLKCSNIMIGGDG---LVKLVDFGTATRLA
||... ||.|    |..|.                 ..|  ..     .|..|||......|..| . | |.|..||..  .|    .|. ||| . .. 
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

RDDIINELQRRKETEADPKKPGLPSEAAKKFN-----LGIKGSPYWI----APECVRSTLYDI---FKADIWSIGCLFIEMFTTYPPFFQFKQVP-----
 .. .   . .               . ....       . |.|. .    |||. ..  ||    .|.|||| |... || . |.||.. ..       
QNNNCD-TNQQ---------------QKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLI

----------ALLYHI-ATITEPPGLPE-----TMSDEGRDFLS----KCLQINPEARASVDDLLAHPWV
           |.  | . ... |  |.     . |.|. ||..    |.|. ||. | . ...| ||| 
TQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase GL50803_1656.AA Ciliate-E2 82-365 19 7.4e-52 176.29 In-house 1-365 (365) Show / Hide 
Range on Protein: 82-365
Range on HMM: 1-365/365
Sequence Identity: 19% (80 aa)

YSLGRIIGHGSFGQVYLALEHLTGKLL------------------AVKEMVVKNCSREVLEAIDAETRILINLR----------------HPNIVNIYDI
| . ..|| |.||.||..   ...|.                   ..|.  .|. .   .|.|  | .|.  ..                ||||...|. 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

EVSDDGNKLLIVMDFIAGGSLASLSK-----SFKGIP------EILCRRYARQILE---------------AIKHMHRQN-VAHLDLKCSNIMIGGDGLV
  . | |.. .||... ||.| .. |     ... |.      |  .... .|||.               |....| .| . | |.| .||..     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLVDFGTATRLA--RDDIINELQRRK---------------ETEADPKKPGLPSEAAKKFNLGI----------KGSPYWIAPECVRSTLYDI-------
|..|||.....   .....  .|..|               .                     .           |.|.  ||| ...  ||        
KIIDFGLSKKYDDDNQNRTH-KQQCKWYMFKNDTSRTPGYMD---------------------QIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGY

-FKADIWSIGCLFIEMFTTYPPFFQFKQVPALLYHIATITE-PPGLP------------------ETMSDEGRDFLSK----CLQINPEARAS-VDDLLA
 .|.||||.|... || . .|||            .  | . .  .|                  .  |.|. |...|    .|| .|| | .  ...| 
DYKCDIWSLGVILYEMLFGKPPF------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN

HPWV
||| 
HPWF
Kinase GL50803_1656.AA CAMKL 82-226 28 8.2e-40 124.64 In-house 1-174 (297) Show / Hide 
Range on Protein: 82-226
Range on HMM: 1-174/297
Sequence Identity: 28% (50 aa)

YSLGRIIGHGSFGQVYLALE-HLTGKLLAVKEMVVKNCS-REVLEA------------IDAETRILINLR---HPNIVNIYDIEVSDDG----NKLLIVM
| .|. .|.||||.| ||.   .||.  |.| .  | .. ... ..            |  | .|.  |.   ||||. .|..   ..     .|. .||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

DFIAGGS--LASLSKSFKG----IPEILCRRYARQILEAIKHMHRQNVAHLDLKCSNIMIGGDG--LVKLVDFG
  . ||.  |    .. ..    .||  .||| |||..|....|.....| |.|  ||..  .|   .|..|||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFG
Kinase GL50803_1656.AA STE20 82-233 32 1.2e-33 118.07 In-house 1-169 (288) Show / Hide 
Range on Protein: 82-233
Range on HMM: 1-169/288
Sequence Identity: 32% (55 aa)

YSLGRIIGHGSFGQVYLALEHLTGKL----LAVKEMVVKNCSR--EVLEAIDAETRILINLRHPNIVNIYDIEVSDDG--NKLLIVMDFIAGGSLASLSK
| | . ||.||.|.||.| .  ||..     |.| | ...|.   . .| |  | .|. ...|||||. |.  . ||   ..| |||.. .||||  . |
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

---SFKG------IPEILCRRYARQILEAIKHMHRQNVAHLDLKCSNIMIGGDGLVKLVDFGTATRLAR
   . ..      . |       |..|.. .. |.... | |.|  ||... || |||.||| .  | .
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTK
Kinase GL50803_1656.AA MEKK15 82-232 34 1e-30 108.38 In-house 1-152 (264) Show / Hide 
Range on Protein: 82-232
Range on HMM: 1-152/264
Sequence Identity: 34% (53 aa)

YSLGRIIGHGSFGQVYLALEHLTGKLLAVKEMVVKNCSREVLEA----IDAETRILINLRHPNIVNIYDIEVSDDGNKLLIVMDFIAGGSLASLSKSFKG
.  | |.|.| .| ||  |   ||.|.||| . . .  .|  .     .  |  .|  |.| |||    . |. . | . | |.|. |||..|.   |  
WKKGNILGKGAYGTVYCGLTN-TGQLIAVKQVELDEIDKEKAKQQYRKLQEEVDLLKTLKHKNIVAY--LGVCLEDNVVNIFMQFVPGGSISSIINRFGP

IPEILCRRYARQILEAIKHMHRQNVAHLDLKCSNIMIGGDGLVKLVDFGTATRLA
..|.   .| .|||. .. .|  .| | |.|  |.|.   |..||.||| | ||.
LDEMVFCKYTKQILQGVQYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRLC
Kinase GL50803_1656.AA MEKK2 82-231 34 5.6e-29 102.2 In-house 1-153 (262) Show / Hide 
Range on Protein: 82-231
Range on HMM: 1-153/262
Sequence Identity: 34% (53 aa)

YSLGRIIGHGSFGQVYLALEHLTGKLLAVKEMVVKNCSREV---LEAIDAETRILINLRHPNIVNIYDIEVSDDGNKLLIVMDFIAGGSLASLSKSFKGI
. .|...| | ||.||.  .  ||. |||| . . . . |     .|.. | ..| ||.|. ||  |          | | |....|||.    | .  .
WRRGKLLGQGAFGRVYVCYDVDTGRELAVKQVQFDPDNPETRKEVQALECEIQLLKNLQHERIVQYYGCLRDNQEKTLSIFMEYMPGGSVKDQLKAYGAL

PEILCRRYARQILEAIKHMHRQNVAHLDLKCSNIMIGGDGLVKLVDFGTATRL
 |   |.| ||||| .. .| . . | |.|  ||.    | ||| ||| ..||
TETVTRKYTRQILEGMHYLHDHMIVHRDIKGANILRDSSGNVKLGDFGASKRL
Kinase GL50803_1656.AA STE20 269-365 38 4.2e-23 81.47 In-house 184-288 (288) Show / Hide 
Range on Protein: 269-365
Range on HMM: 184-288/288
Sequence Identity: 38% (41 aa)

GSPYWIAPECVRS-----TLYDIFKADIWSIGCLFIEMFTTYPPFFQFKQVPALLYHIATITEPP---GL--PETMSDEGRDFLSKCLQINPEARASVDD
|.||| ||| ..        || .|.|||| |   ||| .  ||.| .  . |. ..|.. ..||       |.. |.| .||..||||..|| |.....
GTPYWMAPEVIQCMEGPDKGYD-YKCDIWSLGITAIEMAEGEPPYFDMHPMRAM-FMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQ

LLAHPWV
|| ||..
LLKHPFI
Kinase GL50803_1656.AA MEKK2 267-365 39 2e-22 78.13 In-house 166-262 (262) Show / Hide 
Range on Protein: 267-365
Range on HMM: 166-262/262
Sequence Identity: 39% (39 aa)

IKGSPYWIAPECVRSTLYDIFKADIWSIGCLFIEMFTTYPPFFQFKQVPALLYHIATITEPPGLPETMSDEGRDFLSKCLQINPEARASVDDLLAHPWV
. | |||..|| .    |   |||.|||||  .|| |. ||. ..  . | .. |||    | ||. .|...|||| .| .     | | ..|| | .|
VTGTPYWMSPEVINGEGYGR-KADVWSIGCTVVEMLTEKPPWAEYEAM-AAIFKIATQPTNPQLPQHVSQHARDFLKRCFVEIKQDRPSAEELLRHHFV
Kinase GL50803_1656.AA MEKK15 267-365 38 1e-20 71.81 In-house 167-264 (264) Show / Hide 
Range on Protein: 267-365
Range on HMM: 167-264/264
Sequence Identity: 38% (38 aa)

IKGSPYWIAPECVRSTLYDIFKADIWSIGCLFIEMFTTYPPFFQFKQVPALLYHIATITEPPGLPETMSDEGRDFLSKCLQINPEARASVDDLLAHPWV
..| |||.||| .  | |   |.|||||||   || |  ||. .  .. |. |  |     | ||.  |.. |.|   ||    . |..  .|| ||..
MRGTPYWMAPEVIMETGYGR-KSDIWSIGCTVFEMATRKPPWADMDRMAAMFYIGAHRDPMPQLPVKFSEDARMFVRMCLTRDQHERPTASQLLKHPFI
Kinase GL50803_1656.AA CAMKL 269-365 32 3.5e-16 48.0 In-house 195-297 (297) Show / Hide 
Range on Protein: 269-365
Range on HMM: 195-297/297
Sequence Identity: 32% (34 aa)

GSPYWIAPECVRS--TLYDIFKADIWSIGCLFIEMFTTYPPFFQF-------KQVPALLYHIATITEPPGLPETMSDEGRDFLSKCLQINPEARASVDDL
|||   ||| . .  . || .|.||||.| .   | . | || .        . .  |.  | .  . |  .  .| . ||...| || ||| |......
GSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQI

LAHPWV
. |||.
MNHPWM
Kinase GL50803_1656.AA TyrKc 82-365 23 1e-14 15.24 SMART 1-280 (280) Show / Hide 
Range on Protein: 82-365
Range on HMM: 1-280/280
Sequence Identity: 23% (71 aa)

YSLGRIIGHGSFGQVYLALEHLTGKLLAVKEMVVKNCSREVLEAIDAETRILINL--RHPNIVNIYDIEVSDDG-----NKLLIVMDFIAGGSLASLSKS
 .||...|.| ||.||..         ||| .         .|..  | ||. .|  .|||||..| . ... .       |.||| . ..|.| .  ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

FKG-IPEILCRRYARQILEAIKHMHRQNVAHLDLKCSNIMIGGDGLVKLVDFGTATRLARDDIINELQRRKETEADPKKPGLPSEAAKKFNL--GIKG-S
 .. ..      .. || .   . |..|. | || . |...| .. ||  ||| .  .  ||                     |.  ..     | |.  
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-----------------ESKDYYRKKEHKGGKTML

PY-WIAPECVRSTLYDIFKADIWSIGCLFIEMFTT-YPPFFQ----FKQVPALLYHIATITEPPGLPE-------TMSDEGRDFLSKCLQINPEARASVD
|. | |||| .   . . | |.|| | .  |.||   .|       ..    .. .. .   .|  |.       ...||  .  ..| . .|| | .  
PIRWMAPECINYGKFTT-KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFS

DLLAHPWV
..  |   
EI--HECF
Kinase GL50803_1656.AA Pkinase_Tyr 82-168 28 6.7e-12 40.92 Pfam 1-94 (270) Show / Hide 
Range on Protein: 82-168
Range on HMM: 1-94/270
Sequence Identity: 28% (27 aa)

YSLGRIIGHGSFGQVYLALEH----LTGKLLAVKEMVVKNCSREV---LEAIDAETRILINL-RHPNIVNIYDIEVSDDGN-KLLIVMDFIAGGSL
 ..|. .|.|.||.||..  .     |.   ||| .  |. . .    .|.  .| .|. .| .|||||. | . .....  ...||| . ..|.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML--KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL