Gene GL50803_17560 (G.lamblia)

GL50803_17560

Species: G.lamblia
Alias: GL50803_17560, GK308
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Nek
Subfamily: Nek-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_17560.AA Protein None 619 None Fasta, JSON
GL50803_17560.kin_dom Protein Kinase Domain None 255 None Fasta, JSON

Protein domain

Protein domains of GL50803_17560.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_17560.AA AGC 168-262 20 9.3e-13 27.82 In-house 270-395 (395) Show / Hide 
Range on Protein: 168-262
Range on HMM: 270-395/395
Sequence Identity: 20% (27 aa)

TLQFTAPEVIAGRGYIPQSDLWS--LGATLYACCTGKPP-----------------AILQTIRSQEALETAYFDVSYDVA--------SHASSELASLII
| .. |||..    | .. | ||  ||. .|   ||.||                  . | |.. .   .  ..| ..          .. |.|. .|| 
TPEYMAPEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRY--FINWKVKFPFPEDPQFPEDRWFSPEAKDLIK

SLLAPLAGVRPK----------LSQLRKHPRI
 || .    |.            .....||  
KLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase GL50803_17560.AA Ciliate-E2 157-262 20 1.5e-12 39.35 In-house 239-365 (365) Show / Hide 
Range on Protein: 157-262
Range on HMM: 239-365/365
Sequence Identity: 20% (27 aa)

LPEDVQNMDIQTLQFTAPEVIAGRG---------YIPQSDLWSLGATLYACCTGKPPAILQTIRSQEALETAYFDVSYD-----------VASHASSELA
. ....|  . |. . |||.. | .         |  ..|.|||| .|| ...||||     .. ..  .  ..   ..              . | |  
IQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECK

SLIIS----LLAPLAGVRPK-LSQLRKHPRI
 ||      .|      |.   .|. .|| .
DLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase GL50803_17560.AA RAD53 168-204 38 1.6e-10 27.05 In-house 189-240 (305) Show / Hide 
Range on Protein: 168-204
Range on HMM: 189-240/305
Sequence Identity: 38% (20 aa)

TLQFTAPEVIA--GR-------------GYIPQSDLWSLGATLYACCTGKPP
|.|. |||||.  |.             || .  |.||.|..|| | .| ||
TPQYVAPEVITSKGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPP
S_TKc GL50803_17560.AA S_TKc 8-262 18 2.4e-10 -25.12 SMART 1-231 (231) Show / Hide 
Range on Protein: 8-262
Range on HMM: 1-231/231
Sequence Identity: 18% (50 aa)

FRADHELFRGNDVVSYAGTDGVTRKPV---RITRYMASPGSSTQILKQVRSVRSRFTTHIHAVHHEPKRRIFSVVEPAPCCTAQLLIDLLYANPSDR--V
..   .. .|   . | ...  | . |   .|     .  .  ||||.    .  .  ... | ..   ... | | .. ..  |. |..  ... .  .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---EHIRREIQILKK----HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLF-DYIKKRGRHGLRF

VLHEELIWEIAAASITALGHLADQGLTHMGISPGAIHLTEMGPRLACPRL-----SRTLLPEDVQNMDIQTLQFTAPEVIAGRGYIP-QSDLWSLGATLY
...|  .. ...  . || .. ..|  |  . |  | |.|      .  .     .| |      .  . |. . ||||.   || .  .| ||.| .||
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ACCTGKPPAILQTIRSQEALETAYFDVSYDVASHASSELASLIISLLAPLAGVRPKLSQLRK-------HPRI
 ...|.||   |  .  . .               |.|. ..|  .|      ||   .. .       || .
EMLCGYPPFP-QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase GL50803_17560.AA CAMK 168-262 20 6.8e-10 27.32 In-house 282-425 (425) Show / Hide 
Range on Protein: 168-262
Range on HMM: 282-425/425
Sequence Identity: 20% (30 aa)

TLQFTA-PEVIAG-------------RGYI-PQSDLWSLGATLYACCTGKPPA--------------------ILQTIRSQEAL-ETAYFD---------
|. . | |||. |             . |. |..| ||.|  ||.. .|.||                     ... |.. .   .  ||.         
TPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPE

----VSYD-VASHASSELASLIISLLAPLAGVRPKLSQLRKHPRI
    .| .    . | |  .|| ..| .    |....|  .|| .
WWDDISDEFHH-FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase GL50803_17560.AA CAMKL 168-262 26 7.5e-10 27.47 In-house 196-297 (297) Show / Hide 
Range on Protein: 168-262
Range on HMM: 196-297/297
Sequence Identity: 26% (28 aa)

TLQFTAPEVIAG--RGYI-PQSDLWSLGATLYACCTGKPPAILQTIR-----SQEALETAYFDVSYD--VASHASSELASLIISLLAPLAGVRPKLSQLR
.. . |||...|  . |. |. | ||.| .|||  .|. |   .|.       .  |.       |   . .| | .. .|| ..| .    ||.. |..
SPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIM

KHPRI
.||  
NHPWM
Kinase GL50803_17560.AA Ciliate-E2b 168-204 38 7.6e-10 26.28 In-house 168-209 (272) Show / Hide 
Range on Protein: 168-204
Range on HMM: 168-209/272
Sequence Identity: 38% (16 aa)

TLQFTAPEVIA-----GRGYIPQSDLWSLGATLYACCTGKPP
|. . |||.|      |.||  ..|.||.| .||    |..|
TPHYMAPEIIQSLQPGGKGYTYKVDIWSVGICLYEFMCGYVP
Kinase GL50803_17560.AA ASK 168-262 28 1.2e-09 28.07 In-house 158-254 (254) Show / Hide 
Range on Protein: 168-262
Range on HMM: 158-254/254
Sequence Identity: 28% (28 aa)

TLQFTAPEVI--AGRGYIPQSDLWSLGATLYACCTGKPPAILQTIRSQEALETAYFDVSYDVASHASSELASLIISLLAPLAGVRPKLSQLRKHPRI
|||. |||||    ||| .  |.||.| |.    ||||| .             .. .  .. .  | |    | .  .| .  |.  ..| . | .
TLQYMAPEVIDQGQRGYGKPADIWSFGCTMVEMATGKPPFHELGEPQAAMFKVGMYKKHPEIPEELSAECKNFILRCFEPDPCKRASAQDLLQDPFL
Kinase GL50803_17560.AA SNRK 169-262 34 4e-09 25.75 In-house 163-254 (254) Show / Hide 
Range on Protein: 169-262
Range on HMM: 163-254/254
Sequence Identity: 34% (33 aa)

LQFTAPEVIAGRGY-IPQSDLWSLGATLYACCTGKPPAILQTIRSQEALETAYFDVSYDVASHASSELASLIISLLAPLAGVRPKLSQLRKHPRI
| . |||.. |  |  |  |.||||  ||    |..|  .|     |.| |  .|  | | .| | |   || |.|      |  | ..  |. .
LAYSAPEILLGDSYDAPAVDIWSLGVILYMLVCGQAP--FQEANDSETL-TMIMDCKYTVPDHVSDECRDLIQSMLVRDPKKRASLEEIVSHSWV
Kinase GL50803_17560.AA MSK 168-204 40 9.3e-09 25.72 In-house 168-209 (277) Show / Hide 
Range on Protein: 168-204
Range on HMM: 168-209/277
Sequence Identity: 40% (17 aa)

TLQFTAPEVIA----GRG-YIPQSDLWSLGATLYACCTGKPP
||.. |||...    . | | .. |.||||..||   ||. |
TLHYMAPEMLRRGYAQDGGYDEACDWWSLGVILYTMLTGQVP
Kinase GL50803_17560.AA RSK 168-204 36 1e-08 28.39 In-house 171-211 (278) Show / Hide 
Range on Protein: 168-204
Range on HMM: 171-211/278
Sequence Identity: 36% (15 aa)

TLQFTAPEVIA----GRGYIPQSDLWSLGATLYACCTGKPP
|... |||...    ..|.  . |.||||. .|   ||.||
TIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPP
Kinase GL50803_17560.AA Pkinase 173-204 51 2e-07 27.33 Pfam 179-211 (293) Show / Hide 
Range on Protein: 173-204
Range on HMM: 179-211/293
Sequence Identity: 51% (17 aa)

APEVIA-GRGYIPQSDLWSLGATLYACCTGKPP
|||||  |..| | .| ||.| .||  ..|.||
APEVIRGGQYYGPKVDMWSCGCILYEMLCGRPP