Gene GL50803_17566 (G.lamblia)

GL50803_17566

Species: G.lamblia
Alias: GL50803_17566, GK015
External Links: GiardiaDB ,
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: AMPK

Sequence

Name Sequence Type Origin Length Description Download
GL50803_17566.AA Protein None 643 None Fasta, JSON
GL50803_17566.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of GL50803_17566.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_17566.AA AMPK 38-289 57 5.2e-162 484.72 In-house 1-254 (254) Show / Hide 
Range on Protein: 38-289
Range on HMM: 1-254/254
Sequence Identity: 57% (146 aa)

YIIGKTIGEGSFSKVRLGTHVLTNERIALKIIEKSKITEAADIERITREIQILKLLNHPNVIKLYEIV-DTPRHVYIVQEYMNNGELFDYIVAKGRLSEK
||||||||||.| || .||| ||.|  |.||..| ||.. .. ||| |||.||||..||..|.|||.. .||.  ..| ||  .|||||||| .|||.|.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EACRFLCQLLNGLHFLHSRRIVHRDLKPENLLLTANNDIKIIDFGLSNIFHD-TFMKTCCGSPAYAPPEMIQGKLYSGPSADLWSTGIILYAMLCGCLPF
|||||. | ..|.  .|   ||||||||||||| .|. ||| ||||||.  |  | ||.|||| || ||||.|||| ||  |.||.|.|||||||| |||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

EGSTTQSLYIKILSGEFSTPSYLSQGAKDVLKALLTVNPDDRVTIEELITYPWI
. . | .|| ||..||...|..||. ||| .| .|.|.|  |.||...   || 
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase GL50803_17566.AA CAMKL 38-289 42 1.2e-141 454.9 In-house 1-297 (297) Show / Hide 
Range on Protein: 38-289
Range on HMM: 1-297/297
Sequence Identity: 42% (127 aa)

YIIGKTIGEGSFSKVRLGTH-VLTNERIALKIIEKSKITEAADIER------------ITREIQILKLLN---HPNVIKLYEIVDTPRH------VYIVQ
|.||||.|.|||.||.|.||  .|.|. | |||.|.||..   ...            |.|||||.|.||   |||.|||||...||.|      .|.| 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYMNNGE--LFDYIVAK----GRLSEKEACRFLCQLLNGLHFLHSRRIVHRDLKPENLLLTANND--IKIIDFGLSNIFH------DTFMKTCCGSPAYA
||  .||  ||||||..    ||..|.||.|. .|.. .....||..|||||.||||.||. |..  |||||||.||..       . ..||.||||.|.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

PPEMIQG--KLYSGPSADLWSTGIILYAMLCGCLPFEGST---------TQSLYIKILSGEFSTPSYLSQGAKDVLKALLTVNPDDRVTIEELITYPWI
.||..||  | | || .| || |.|||||.|| |||.. |         .  . |... ...  ....|  ..| .. .|.|||..| ||...   || 
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase GL50803_17566.AA CAMK 43-289 29 4.8e-131 424.79 In-house 1-425 (425) Show / Hide 
Range on Protein: 43-289
Range on HMM: 1-425/425
Sequence Identity: 29% (124 aa)

TIGEGSFSKVRLGTHVLTN------------ERIALKIIEKSKITE-------------------------AADIERITREIQILKL-------LNHPNV
|.|.|||.||.|..| .|.            .. | |||.|.|...                         . | ... |||.|.|.       |.|||.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKLYEIVD------------TPRH--------VYIVQ---EYMNNGEL----FDYIVAK---------------GRLSEKEACRFLCQLLNGLHFLHSRR
|||||. .            | ..        .|.|    ||. .|||    |||||..               ||..|.||.|.  |.. ..|..||. 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHRDLKPENLLLTAN-----------------NDIKIIDFGLSNIFH-------------------------DTFMKTCCGSPAYAP-PEMIQG-----
||||||||||.||. |                 |.|||||||..|.|                          .  |||.||.|.|.. ||...|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------KLYSGPSADLWSTGIILYAMLCGCLPFEGS-------------TTQSLYIKILSGEFS-TPSY-----------------------LSQGAK
        | | ||..| || |.|||.||||..||.|.             . . |. ||..|...  |.|                       .|| .|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DVLKALLTVNPDDRVTIEELITYPWI
| .. .|.|.|..| |||.    ||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase GL50803_17566.AA MARK 38-289 44 1.9e-125 411.94 In-house 1-262 (262) Show / Hide 
Range on Protein: 38-289
Range on HMM: 1-262/262
Sequence Identity: 44% (116 aa)

YIIGKTIGEGSFSKVRLGTHVLTNERIALKIIEKSKITEAADIERITREIQILKLLNHPNVIKLYEIVD--TPRH-VYIVQEYMNNGELFDYIVAK--GR
| ..||||.||..||.|..|..|... |.||.|| |...   .. . |||.|.|.|.|||.|||.....  |..| .|.. ||  .|||.|||.|.  ||
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LSEKEACRFLCQLLNGLHFLHSRRIVHRDLKPENLLLTANN--DIKIIDFGLSNIF-HDTFMKTCCGSPAYAPPEMIQGKLYSGPSADLWSTGIILYAML
|.|.|| |.  |.. .....||..|||||.||||.|. .|.  .|||||||.|...  ..  .|.||.|.|..||....| | || .| || |..||.|.
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

CGCLPFEGST--TQSLYIKILSGEFSTPSYLSQGAKDVLKALLTVNPDDRVTIEELITYPWI
||..||.|.|     || |||.|... |...| .... .. ||||||..| ||||.   ||.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase GL50803_17566.AA CAMK1 38-289 41 2e-114 334.05 In-house 1-276 (276) Show / Hide 
Range on Protein: 38-289
Range on HMM: 1-276/276
Sequence Identity: 41% (116 aa)

YIIGKTIGEGSFSKVRLGTHVLT---NERIALKIIEKSKITEAADI---ERITREIQILKL---LNHPNVIKLYEIVDTPRHVYIVQEYMNNGELFDYIV
|..||.||.|.||.|.|.||  |   .. .|.|.|.| | ..  |    |.. .||.|.|    ..|||.||.||. ....|.|.|.|....||||| ||
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

AKGRLSEKEACRFLCQLLNGLHFLHSRRIVHRDLKPENLLLTAN-ND--IK--IIDFGLSNIFHDT--FMKTCCGSPAYAPPEMIQG---KLYSGPSADL
 ||  .||.|..   |.|  ....||. ||||||||||||.  . .|  ||  |.||||| || .   .|||.||.| |  ||.. .   | | . . |.
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPY-DKACDM

WSTGIILYAMLCGCLPFEGST-TQSLYIKILSGEFSTPSY----LSQG-AKDVLKALLTVNPDDRVTIEELITYPWI
|| |.|.| .|||. || ...  . |. ||...|.  ||      | . ||| .| .|.|.|  | |.|. .  |||
WSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase GL50803_17566.AA NuaK 38-289 42 1e-110 292.38 In-house 1-252 (252) Show / Hide 
Range on Protein: 38-289
Range on HMM: 1-252/252
Sequence Identity: 42% (108 aa)

YIIGKTIGEGSFSKVRLGTHVLTNERIALKIIEKSKITEAADIERITREIQILKLLNHPNVIKLYEIVDTPRHVYIVQEYMNNGELFDYIVAKGRLSEKE
| . || |.| . ||.|.|   |   .| | | |.|| . .|. .| |||.|.  ||||..|. ||.      . || ||   |||.|||  ...|.|.|
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPERE

ACRFLCQLLNGLHFLHSRRIVHRDLKPENLLLTANNDIKIIDFGLSNIFHD-TFMKTCCGSPAYAPPEMIQGKLYSGPSADLWSTGIILYAMLCGCLPFE
| .|  |    .|. |  ||.||||| || || .|...|| ||||||..||  |..| |||| || || . |. | ||  | || |..||.|  | .||.
ARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFD

GSTTQSLYIKILSGEFSTPSYLSQGAKDVLKALLTVNPDDRVTIEELITYPWI
|.  . |   | .|..  |   |. |      .|.|||. | ||..    .|.
GHDFKHLVKQISQGAYYEPCKPSD-ACMLIRWMLMVNPRRRATIYDICHHWWV
Kinase GL50803_17566.AA QIK 38-289 42 1.5e-110 373.6 In-house 1-272 (272) Show / Hide 
Range on Protein: 38-289
Range on HMM: 1-272/272
Sequence Identity: 42% (117 aa)

YIIGKTIGEGSFSKVRLGTHVLTNERIALKIIEKSKITEAADIERITREIQILKLLNHPNVIKLYEIVDTPRHVYIVQEYMNNGELFDYIVAKGR-----
| |..||| | |  |.|..|  | ...| ||| ||...|  ..... ||.||.|.|.||..||||..  | .  ||| ||  |||.|||....||     
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDE-ENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------LSEKEACRFLCQLLNGLHFLHSRRIVHRDLKPENLLLTANNDIKIIDFGLSNIFHDTF-MKTCCGSPAYAPPEMIQGKLYSGPSA
               ..|.|| |   |.. . |..|.| ||||||| ||.|| .| .|||.|||.|| |     ..|.||||.|| ||| .|| | || .
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKV

DLWSTGIILYAMLCGCLPFEGSTTQSLYIKILSGEFSTPSYLSQGAKDVLKALLTVNPDDRVTIEELITYPWI
| || |..||.. || ||| |.| |.|  ..||| |  | ..||.  .  .  |.|.|. | ||.  .  .|.
DIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase GL50803_17566.AA S_TKc 38-289 37 5.8e-108 365.9 SMART 1-231 (231) Show / Hide 
Range on Protein: 38-289
Range on HMM: 1-231/231
Sequence Identity: 37% (99 aa)

YIIGKTIGEGSFSKVRLGTHVLTNERIALKIIEKSKITEAADIERITREIQILKLLNHPNVIKLYEIVDTPRHVYIVQEYMNN--GELFDYIVAKGR---
| |...||.|.|.||....|. |... |.|||           |.| |||||||  .|||..|||.. ..  |.|.| ||...  |.|||||. .||   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LSEKEACRFLCQLLNGLHFLHSRRIVHRDLKPENLLLTANNDIKIIDFGLSNIFHDTFMKTCCGSPAYAPPEMIQGKLYSGPSADLWSTGIILYAML
   ..| .|.....|....| ..||..|.||||||||.||.    |||.||||. ..     .|.||.| | .||..    |.....| || |.||| ||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

CGCLPFEGSTTQSLYIKILSGEFSTPSYLSQGAKDVLKALLTVNPDDRVTIEELIT-------YPWI
||. ||.   .. . .|..          |. ||| .. .|...|..| |. |. .        ||.
CGYPPFP---QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase GL50803_17566.AA Pkinase 38-289 35 2e-103 354.73 Pfam 1-293 (293) Show / Hide 
Range on Protein: 38-289
Range on HMM: 1-293/293
Sequence Identity: 35% (106 aa)

YIIGKTIGEGSFSKVRLGTHVLTNERIALKIIEKSKITEAADIERIT-REIQILKLLNHPNVIKLYEIVDTPRHVYIVQEYMNNG----ELFDYIV--AK
| ||..||.|||..|....|. |... |.|||.|... .  |....  .||||.| |||||...||... ...|.|.|.||...|    .|||||   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GRL--SEKEACRFLCQLLNGLHFLHSRRIVHRDLKPENLLLTANNDI----KIIDFGLSN---IFHDTFMKTCCGSPAYAPPEMIQGKLYSGPSADLWST
|..  ||.|..... |.| || ..||..|.||||||||.|.  |..|    ||.||||.    . ... |.| ||.| |..|| |.|  | ||..| || 
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GIILYAMLCGCLPFEGS------TTQSLYIKILSGEFSTPSYLS---------------------QGAKDVLKALLTVNPDDRVTIEELITYPWI
|.||| |||| .|| |.      . . .. .|...... ... .                     . .||..| .|...| .| |.|..   ||.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase GL50803_17566.AA MELK 38-289 41 1.8e-94 320.15 In-house 1-254 (254) Show / Hide 
Range on Protein: 38-289
Range on HMM: 1-254/254
Sequence Identity: 41% (107 aa)

YIIGKTIGEGSFSKVRLGTHVLTNERIALKIIEKSKITEAADIERITREIQILKLLNHPNVIKLYEIVDTPRHVYIVQEYMNNGELFDYIVAKGRLSEKE
| . ..|| | |.||.| .|.|||...|.||..| ..    |. |.  |.. || | | .. .|| ...|   ...| ||   ||.||||. . ||.|.|
YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQL--GHDLPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEE

ACRFLCQLLNGLHFLHSRRIVHRDLKPENLLLTANNDIKIIDFGLSNIF---HDTF-MKTCCGSPAYAPPEMIQGKLYSGPSADLWSTGIILYAMLCGCL
.  |. |..  . ..||.   ||||||||||.. .  .|.|||||        |   ..||||||||| ||.|||| | |  ||.|| ||.||...|| |
TRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFL

PFEGSTTQSLYIKILSGEFSTPSYLSQGAKDVLKALLTVNPDDRVTIEELITYPWI
||.    . .| ||.|| .  | .||  .|..|...| |.|. |. . .|.  ||.
PFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase GL50803_17566.AA BRSK 38-289 43 1.6e-92 313.65 In-house 1-254 (254) Show / Hide 
Range on Protein: 38-289
Range on HMM: 1-254/254
Sequence Identity: 43% (110 aa)

YIIGKTIGEGSFSKVRLGTHVLTNERIALKIIEKSKIT-EAADIERITREIQILKLLNHPNVIKLYEIVDTPRHVYIVQEYMNNGELFDYIVAKGRLSEK
|...|| | |   .|.||.|  | ...| ||| | |         .. ||| |.|| .||.|.|.|..  . .  | . |.   |||||| | ||||  |
YRLEKTLGKGQTGLVKLGVHCVTGKKVAIKIINKEKLSNKESMLMKVEREIAIMKLIDHPHVMKMYDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPK

EACRFLCQLLNGLHFLHSRRIVHRDLKPENLLLTANNDIKIIDFGLSNI-FHDTFMKTCCGSPAYAPPEMIQGKLYSGPSADLWSTGIILYAMLCGCLPF
|| .|  |   .| | ||. | |||||||||||   | ||| |||.  .  .|  . | |||| || || |.|  | |  ||.|| |.||||.| | |||
EARKFFRQIISALDFCHSHNICHRDLKPENLLLDEKNNIKIADFGMASLQVKDMMLHTSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPF

EGSTTQSLYIKILSGEFSTPSYLSQGAKDVLKALLTVNPDDRVTIEELITYPWI
       |  |.  | |. | .  . . | |.....|.|| |....|    || 
DDDNLRQLLEKVKRGVFHMPHFIHPDCQDLLRGMIEVDPDKRISLKEIQKHPWY
Kinase GL50803_17566.AA Ciliate-E2 38-289 26 1.2e-84 287.55 In-house 1-365 (365) Show / Hide 
Range on Protein: 38-289
Range on HMM: 1-365/365
Sequence Identity: 26% (101 aa)

YIIGKTIGEGSFSKVRLGTHVLTNER-----------------------IALKIIEKSKITEAADIERITREIQ----------ILKLLNHPNVIKLYEI
|.. | ||.|.|..|..... .....                       .|.||..|..| .   ...| |||.          ||..|||||.||.|| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VD--TPRHVYIVQEYMNNGELFDYIV------------AKGRLSEKEACRFLCQLLN---------------GLHFLHSRR-IVHRDLKPENLLLTANND
    .  ..|.| || . |.|||||             . ....|||....  |.|.               .|..|||.  |.|||.||||.|.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

IKIIDFGLSNIFHD---------------------------------TFMKTCCGSPAYAPPEMIQGKLYSG--------PSADLWSTGIILYAMLCGCL
||||||||| ...|                                    .|.||.| | .||...|| |..         ..|.|| |.||| ||.| .
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFEGSTTQSLYIKILSGEFSTP------------------SYLSQGAKDVLKA----LLTVNPDDRVT-IEELITYPWI
||        ...|. .... |                   ..|| .|| .|     .| ..|. | | .|...  ||.
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase GL50803_17566.AA Pkinase_Tyr 38-183 35 1e-26 91.1 Pfam 1-158 (270) Show / Hide 
Range on Protein: 38-183
Range on HMM: 1-158/270
Sequence Identity: 35% (56 aa)

YIIGKTIGEGSFSKVRLGTHV----LTNERIALKIIEKSKITEAAD--IERITREIQILKLL-NHPNVIKLYEIVD-TPRH--VYIVQEYMNNGELFDYI
 ..||..|||.| .|..||       |.   | |.. |   .   .  .|   ||..|.| | .|||...|| ..    ..  .||| ||| .| | || 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

VA----KGRLSEKEACRFLCQLLNGLHFLHSRRIVHRDLKPENLLLTANNDIKIIDFGLS
 .    |..|. |. . .  |  .|. .|.|....||||   | |.| || .|| ||||.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase GL50803_17566.AA TyrKc 38-289 25 1.5e-17 61.24 SMART 1-280 (280) Show / Hide 
Range on Protein: 38-289
Range on HMM: 1-280/280
Sequence Identity: 25% (75 aa)

YIIGKTIGEGSFSKVRLGTHVLTNERIALKIIEKSKITEAADIERITREIQILKLL--NHPNVIKLYEIVDTP-------RHVYIVQEYMNNGELFDYIV
   ||..||| | .|..||     .  | | . ...      .| . ||..|.. |  .|||...|| .. ..         ..|| ||| .| | ||. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

AKGR-LSEKEACRFLCQLLNGLHFLHSRRIVHRDLKPENLLLTANNDIKIIDFGLS-NIFHD--------TFMKT---CCG--SP-AYAPPEMIQGKLYS
.... |. |. . |  |  .|  .|||....||||   | |...|. .|| ||||| .| .|        . .|.   ..    |    .|| |. . ..
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

GPSADLWSTGIILYAML-CGCLPFEG-----STTQSLYIKILSGEF-STPSY--------LSQGAKDVLKALLTVNPDDRVTIEELITYPWI
 .  | || |. .. ..  |  | .|      . | .. .. .|.    | .         ..   .. |     .|.|| | .|.  .  .
-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase GL50803_17566.AA APH 140-183 16 0.000986 13.61 Pfam 158-202 (248) Show / Hide 
Range on Protein: 140-183
Range on HMM: 158-202/248
Sequence Identity: 16% (8 aa)

RFLCQLLNGLHFLHSRRIVHRDLKPENLLLT--ANNDIK--IIDFGLS
|.. .|.. ..    ....|.|..| |....  ....    .||.. .
RLWAWLEAHWP---PPCWCHGDFHPGNVMWDPRPDGGRVTGVIDWDDA