Gene GL50803_17625 (G.lamblia)

GL50803_17625

Species: G.lamblia
Alias: GL50803_17625, GK035
External Links: GiardiaDB ,
Annotation:

Classification

Group: CMGC
Family: GSK

Sequence

Name Sequence Type Origin Length Description Download
GL50803_17625.AA Protein None 350 None Fasta, JSON
GL50803_17625.kin_dom Protein Kinase Domain None 285 None Fasta, JSON

Protein domain

Protein domains of GL50803_17625.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_17625.AA GSK 28-312 41 2.1e-143 441.15 In-house 1-328 (328) Show / Hide 
Range on Protein: 28-312
Range on HMM: 1-328/328
Sequence Identity: 41% (136 aa)

FTTMRTIGSGSFGVVFIAKTS-----TGEL----IAIKKVFQDRKYR-NRELSIMQELG--QHPCIIRLINSYISVATNQTNG-DFLN-ILMDYYQENGY
...|. ||.||||||. |. .     |.|     .|||||.||..|. |||| ||..||   || |.||.... . .... ..  ..| . |.|  .. |
YEEMKVIGHGSFGVVYQAYMNSPSNETKEIWLGPVAIKKVWQDKRYKCNRELQIMKMLGKLDHPNIVRLKYFFYMHYEKKDENHVYCNCLVMEYMPQTLY

QIYKSYIRAGIKMPMFHIKLYTFQFLRGLAYMHSFNIANRDLKPQNTLVNRESGRAVLCDLGSAKKLNP--AEPNIAYICSRYYRAPELIFGSRYYTTVI
|. . | ... .||. |||||..| .||||| ||..|. ||.|||| ||....|.  .|| ||||.| |   ||||.|||||||||||||||. .||. |
QVIRHYVKNKQQMPIIHIKLYMYQMFRGLAYLHSHGICHRDIKPQNILVDPDTGVLKICDFGSAKQLEPNKNEPNISYICSRYYRAPELIFGCTNYTCQI

DIWSFGCVVAEMIIGKPIYAGSSPLDQIIEIIKILGPPSLKELKEMNPTLKEYAFP---TIRTTP------------------------MSDVLGTKDPV
|.||.|||.|||..|.|. .| | .||..||||.|| |.  ....|||  .|. ||    ....|                        |  ...|... 
DVWSCGCVMAEMLKGQPLFPGDSSVDQLVEIIKMLGTPTKEQIQSMNPSYPEFKFPYWSFQQIKPHPWQKNDTKYEYQTYYHKKYRTVYMFKWCHTDMQD

VLDFFARCFKYSPNERITAYEALAHPFY
..|.  .|..| |..|....||.||||.
WIDLISKCLVYDPKKRLSPLEACAHPFF
Kinase GL50803_17625.AA CMGC 28-312 20 8.8e-97 318.57 In-house 1-513 (513) Show / Hide 
Range on Protein: 28-312
Range on HMM: 1-513/513
Sequence Identity: 20% (105 aa)

FTTMRTIGSGSFGVVFIAKT---------------STGELIAIKKVFQDRKYRN----------------RELSIMQELG----------------QHPC
.. .. ||.|..|||. ..                 |.|..||||....  | .                ||..|...|                 .|. 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IIRLINSYISVATNQTNGD----------FLNILMDYYQENGYQIYKSYIR-----AGIKMPMFH------------IKLYT------FQFLRGLA--YM
|..|.... .  .. .. .           |.. ..| . . ||. |.. .      .....  |            || ..      .| ||||.  |.
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSFN--IANRDLKPQNTLVNRE-------------------SGRAVLCDLGSAKKLNPA----------------------EPNIAYICSRYYRAPELIF
|| .  |  |||||.| |.| .                   .||  .|| |.|....|                       .|.  |...|.|||||...
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

GSRYYT---------TVIDIWSFGCVVAEMIIG--------KPIYA-----------GSSPLDQIIEIIKILGPPS---------------LKELKEMNP
|...||         | ||.||.||. |||. |        ||.             |.| .||. .|.|.||.|.                .|  .|..
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

------------------TLKEYA---------FPTIRTTPMSDVLGT-----------------------------------KDPVVLDFFARCFKYSP
                  ...| |         ||...  | ...                                       ||  .|.  ....| |
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

NERITAYEALAHPFY
..|||| .||.||. 
DKRITAEQALQHPYF
Kinase GL50803_17625.AA S_TKc 28-312 25 7.7e-72 245.9 SMART 1-231 (231) Show / Hide 
Range on Protein: 28-312
Range on HMM: 1-231/231
Sequence Identity: 25% (76 aa)

FTTMRTIGSGSFGVVFIAKTST-GELIAIKKVFQDRKYRNRELSIMQELGQHPCIIRLINSYISVATNQTNGDFLNILMDYYQE---NGYQIYKSYIRAG
.. .|.||.|.||.|. ..    |.. |||..    .   ||..|...  .|| |..|. .. .        |.| . |.|      . ... |.. | |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---EHIRREIQILKK--HHPNIVKLYDVFQD--------DHLYMVMEYCDGDLGDLFDYIKKRGRHG

--IKMPMFHIKLYTFQFLRGLAYMHSFNIANRDLKPQNTLVNRESGRAVLCDLGSAKKLNPAEPNIAYICSRYYRAPELIFGSRYYTT-VIDIWSFGCVV
   ..|  |.. |. | ...|.|.|| .|  |||||.| |...   .  .|| |.|..|        .. ...|.|||..     |..  .|.||.||..
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCIL

AEMIIGKPIYAGSSPLDQIIEIIKILGPPSLKELKEMNPTLKEYAFPTIRTTPMSDVLGTKDPVVLDFFARCFKYSPNERITAYEALA-------HPFY
.||. |.| .       |. ...|..|                                  .| ..||  .|... |..|.|| |||.       ||. 
YEMLCGYPPFP------QMQMMFKKIG----------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase GL50803_17625.AA Pkinase 28-312 27 2.4e-66 231.5 Pfam 1-293 (293) Show / Hide 
Range on Protein: 28-312
Range on HMM: 1-293/293
Sequence Identity: 27% (87 aa)

FTTMRTIGSGSFGVVFIAK-TSTGELIAIKKVFQDRKYRNR--------ELSIMQELGQHPCIIRLINSYISVATNQTNGDFLNILMDYYQEN----GYQ
... |.|||||||.|....  .||.. |.|..  ...  .         |..||..| .||.|.||. .. .       .| . . |.| .         
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED-------KDHIYMVMEYCEGGLYVMDLF

IYKSYIR--AGIKM--PMFHIKLYTFQFLRGLAYMHSFNIANRDLKPQNTLVNRESGRA----VLCDLGSAKK--LNPAEPNIAYICSRYYRAPELIFGS
   .||.  .. ..  .. ..| |  | ||||.|.|| .|  |||||.| |.. . |       .|| |.||.  . . . .  . ....|.|||.| |.
---DYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGG

RYYTTVIDIWSFGCVVAEMIIGKPIYAGS----SPLDQIIEIIKILGPPSLKELKEMNPTLKEYAFPTIRTTPMSDVLGTKDPVVLDFFARCFKYSPNER
.||.. .|.||.||...||. |.|.. |.    . .||.  | .|.|||   .  . ..   .. |.. ...  . .    ..  .||  .|... |..|
QYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-WHF-HWTF-HNWSEECKDFIKWCLCKDPKKR

ITAYEALAHPFY
.|| ..| ||. 
PTAEQILQHPWF
Kinase GL50803_17625.AA CDK 28-312 27 4e-53 168.23 In-house 1-284 (284) Show / Hide 
Range on Protein: 28-312
Range on HMM: 1-284/284
Sequence Identity: 27% (91 aa)

FTTMRTIGSGSFGVVFIAKTST-G-----ELIAIKKVF---Q----DRKYRN----RELSIMQELGQHPCIIRLINSYISVATNQTNGDF-----LNILM
.     || |..|||. |.    |     ...|.||.    .    ..   .    || |...||  || |..|.  ... ..  .|  .     | . .
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNN-KDKHENKLYMVF

DYYQEN--GYQIYKSYIRAGIKMPMFHIKLYTFQFLRGLAYMHSFNIANRDLKPQNTLVNRESGRAV-----LCDLGSAKKLN-------PAEPNIAYIC
.|      .|                 || |..| ||||.|.|| .|  ||||||| |.| . |  .     . | | |.. .       |  .    . 
EYMDHDLKKYMD---------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILIN-NNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVV

SRYYRAPELIFGSRYYT--TVIDIWSFGCVVAEMII---GKPIYAGSSPLDQIIEIIKILGPPSLKELKEMNPTLKEYAFPTIRTTPMSDVLGTKDPVVL
 . |||||| .||. |.  | ||.||.||. |||.    .||.  |.| .||.  |..|.| |. .   ..   | .|                      
TLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVT-KLPDY----------------------

DFFARCFKYSPNERITAYEALAHPFY
|.  ... | |. ||.| .|| ||. 
DLLNKMLCYDPKKRISAEQALQHPYF
Kinase GL50803_17625.AA MAPK 28-312 28 5.6e-50 170.97 In-house 1-328 (328) Show / Hide 
Range on Protein: 28-312
Range on HMM: 1-328/328
Sequence Identity: 28% (94 aa)

FTTMRTIGSGSFGVVFIAKTS-------TGELIAIKKV---FQDRKYRN---RELSIMQELGQHPCIIRLINSYISVA--TNQTNGDFLNI--LMDYYQE
..  . ||.|..|||. |.         .|. .||||.   ||.  .     ||. .......|. ||.|.. .   .   . ....|  |   |.. . 
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

NGYQIYKSYIRAGIKMPMFHIKLYTFQFLRG--LAYMHSFNIANRDLKPQNTLVNRESGRAVLCDLGSAKKLNPAEPNIA---------------YICSR
. .|| ||      ..   ||.  ..| |||  | |.|| |.  ||||| | ||| | .   .|| | | .. | .  .                |.  |
DLHQIIKSQQ----PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVN-ENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATR

YYRAPELIFG--SRYYTTVIDIWSFGCVVAEMII-GKPIYAGSSPLDQIIEIIKILGPPSLKELKEMN-P-TLKEYAF-----PTIRTTPMSDVLGT---
.|||||....  .. ||. .|.|| ||  |||.  .||.  |....||.  |...|| ||   .. .  .   ..|       |     | ....     
WYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANF

-KDPVVLDFFARCFKYSPNERITAYEALAHPFY
 ..|  .|.  .    .|..|||. |||.||. 
NANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase GL50803_17625.AA RCK 101-312 28 2.5e-48 151.28 In-house 75-298 (298) Show / Hide 
Range on Protein: 101-312
Range on HMM: 75-298/298
Sequence Identity: 28% (65 aa)

LNILMDYYQENGYQIYKSYIRAGIK-MPMFH--IKLYTFQFLRGLAYMHSFNIANRDLKPQNTLVNRE--------SGRAVLCDLGSAKKLNPAEPNIAY
| . . | ..| || .|..   . | .| .   || . .| | |||.||. ..  ||||| | ... .        ...  ..| |...      |. .|
LYFVFEYMDMNLYQMMKDFKE-RRKYLPENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPPYTDY

ICSRYYRAPELIFGSRYYTTVIDIWSFGCVVAEMIIGKPIYAGSSPLDQIIEIIKILGPPSLKELKEMN--PTLKEYAFPTIRTTPMSDVLGTKDPVVLD
. .|.|||||..  . ||.. .|||..||. .|  . .| ..||| .||| .|.|..| |. |.. .     . ... ||    .|.. ..    .  ..
VSTRWYRAPECLLRCTYYNSPMDIWAVGCIMYELYMLRPLFPGSSEIDQIFKICKVMGTPNKKDWPDGYKLASQMNFNFPQCKGMPLKQLIPNCSQDCIE

FFARCFKYSPNERITAYEALAHPFY
    . .. |..||||..|| ||. 
LMEKMLQWDPQKRITAQQALQHPYF
Kinase GL50803_17625.AA CDC2 28-312 28 5.1e-48 145.36 In-house 1-301 (301) Show / Hide 
Range on Protein: 28-312
Range on HMM: 1-301/301
Sequence Identity: 28% (90 aa)

FTTMRTIGSGSFGVVFIAK-TSTGELIAIKKVFQDRKYRN--------RELSIMQELGQHPCIIRLINSYISVATNQTNGDFLNILMDYYQENGYQIYKS
..  . || |..|||. .| . |....|.||.  ..            ||.|...|| .|| |..|   ...    .   ..|.    .|...  .    
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKN--

YIRAGIKMPMFHIKLYTFQFLRGLAYMHSFNIANRDLKPQNTLVNRESGRAVLCDLGSAKKLNPAEPNIAYICS-----RYYRAPELIFGSRYYTTVIDI
      .||   .| |..| |.|... |.  |  ||||||| |.... |.  . | | |.  .   |  .|        . |||||. .|...|.| .|.
-----KHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKK-GNIKIADFGLARAFG--IPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDM

WSFGCVVAEM---IIGKPIYAGSSPLDQIIEIIKILGPPSLKELKEMNPTLKEY--AFPTIRTTPMSDVLGT---------KDPVVLDFFARCFKYSPNE
||.||. |||   .  ||. .| |  ||.  | .||| |. ... ..   |..|   ||  ... .|...            ||  .|   .   | |. 
WSIGCIFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVT-QLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQK

RITAYEALAHPFY
||.| |||.||. 
RISAKEALQHPYF
Kinase GL50803_17625.AA CDK5 131-312 33 1.3e-43 135.38 In-house 100-287 (287) Show / Hide 
Range on Protein: 131-312
Range on HMM: 100-287/287
Sequence Identity: 33% (63 aa)

IKLYTFQFLRGLAYMHSFNIANRDLKPQNTLVNRESGRAVLCDLGSAKKLN-PAEPNIAYICSRYYRAPELIFGSRYYTTVIDIWSFGCVVAEMI-IGKP
|| . .| |.|||. |. ..  ||||||| |.|.. |   | | | |     |     . .    ||.|   .||. |.| ||.|| ||. |||.  |.|
IKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKN-GELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRP

IYAGSSPLDQIIEIIKILGPPSLKELKEMNPTLKEY-----AFPTIRTTP-MSDVLGTKDPVVLDFFARCFKYSPNERITAYEALAHPFY
 . |..  ||   | ||.| |.  .   .   | .|     ..|    .. .. .    |   .|.  .  .. ||.||.| .|| ||..
LFPGNDVEDQLKRIFKIMGTPCEDKWPSIT-KLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase GL50803_17625.AA STE 28-312 22 5.6e-41 142.46 In-house 1-359 (359) Show / Hide 
Range on Protein: 28-312
Range on HMM: 1-359/359
Sequence Identity: 22% (86 aa)

FTTMRTIGSGSFGVVFIAKTS----------------TGELIAIKKVF---------------------QDRKYRNRELSIMQELGQ-HPCIIRLINSYI
.. .. ||.|.||.|. |.                  |||..|||..                      ....   .|..||... . || |.. . .|.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

SVATNQTNGDFLNILMDYYQ-ENGYQIYKSYIRAGI----------KMPMFHIKLYTFQFLRG-LAYMHSFNIANRDLKPQNTLVNRESGRAVLCDLGSA
   .|. |.| |.| | |       .|.|..   |           ..|   |. ...| |.| |.| || .|  ||.||.| |.      . ||| | .
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL------VKLCDFGVC

KKLNP-----------------AEPNIAYI-CSRYYRAPELIFG-----SRYYTTVIDIWSFGCVVAEMIIGKPIYAGSSPLDQIIEIIKI---------
..|..                 .. .   . .   . ||| | .     .  |.|  ||||.||.. ||. ||| ..  .|.  . .|..          
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP--WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQ

-----LGPPSLKE-------------LKEMNPTLKEYAFPTIRTTPMSDVLGTKDPVVLDFFARCFKYSPNERITAYEALA--HPFY
      .||.|..             ..                     .     |   || ..|... ||.| || . |   ||| 
LCIVNGPPPPLPDHLSQNEMISYGGSGT-T-------------------YPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase GL50803_17625.AA ERK7 130-312 31 7.4e-40 133.8 In-house 101-292 (292) Show / Hide 
Range on Protein: 130-312
Range on HMM: 101-292/292
Sequence Identity: 31% (60 aa)

HIKLYTFQFLRGLAYMHSFNIANRDLKPQNTLVNRESGRAVLCDLGSAKKLNPAE------PNIA-YICSRYYRAPELIFGSRYYTTVIDIWSFGCVVAE
| .   .| || . |||| |.  ||||| | |.. |  .  .|| | |  .   |      | .  |.  | |||||   ||. ||  .| || ||...|
HKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSEC-MVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILGE

MIIGKPIYAGSSPLDQIIEIIKILGPPSLKELKEMNPTLKEY---AFPTIRTTPMSDVLGTKDPVVLDFFARCFKYSPNERITAYEALAHPFY
|..|||...|.| ..||  |..... |. .... ... .      . .. .. ......    .  .|   |   . |..|.|| .||.||. 
MLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase GL50803_17625.AA ERK5 130-312 36 7.5e-39 135.39 In-house 104-295 (295) Show / Hide 
Range on Protein: 130-312
Range on HMM: 104-295/295
Sequence Identity: 36% (71 aa)

HIKLYTFQFLRGLAYMHSFNIANRDLKPQNTLVNRESGRAVLCDLGSAKKLNP---AEPNI---AYICSRYYRAPELIFGSRYYTTVIDIWSFGCVVAEM
||. . .| |||| |||| ..  ||||| | ||| |     . | | |. |     ..  .    |.  |.||||||.| |  ||  ||.|| ||.. ||
HIRYFLYQILRGLKYMHSAQVIHRDLKPSNLLVN-ENCELKIGDFGMARGLCTFSPDKHQMFMTEYVATRWYRAPELMFSSHDYTQAIDVWSVGCIFGEM

IIGKPIYAGSSPLDQIIEIIKILGPPSLKELKEMNP-TLKEY---AFPTIRTTPMSDVLGTKDPVVLDFFARCFKYSPNERITAYEALAHPFY
|  . .. |  ...|.  |...|| |. . .. .    .. |    ||  .  ... |    |.  ||  ||  .. | ||||. .|| ||| 
IARRQMFPGKNYIHQLQLIMMVLGMPPPHMIQAVSADHVYNYFQKNFPNRQPKDWEKVYPKADRQALDLLARMLRFEPSERITVNKALQHPFL
Kinase GL50803_17625.AA TyrKc 28-315 20 2e-10 -54.2 SMART 1-280 (280) Show / Hide 
Range on Protein: 28-315
Range on HMM: 1-280/280
Sequence Identity: 20% (66 aa)

FTTMRTIGSGSFGVVFIAKTSTGELIAIKKVFQDRKYRN--RELSIMQELG-QHPCIIRLINSYISVATNQ-----------------TNGDFLNILMDY
 |  ...|.| ||.|. .. .  .  |.|..  |   .   ||..|| .|| .||.|.||    . |.| |                  .|| .. | ..
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRL----YGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

YQENGYQIYKSYIRAGIKMPMFHIKLYTFQFLRGLAYMHSFNIANRDLKPQNTLVNRESGRAVLCDLGSAKKLNPA----EPNIAYI-----CSR-----
  .                .| .   . .|  .| .| || |.  |||   | ||...  ..  .| | ....       |    |      ...     
RPK---------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPI

YYRAPELIFGSRYYTTVIDIWSFGCVVAEMI-IGKPIYAGS----SPLDQIIEIIKILGPPSLKELKEMNPTLKEYAFPTIRTTPMSDVLGTKDPVVLDF
   ||| |. ... |   |.|||| .  |.   |.. | |      . ...|| .|  . .   .  .  | .             .    .  . . . 
RWMAPECINYGKFTTKS-DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY--P-MS------------F---VCCPDEMYQI

FARCFKYSPNERITAYEALAHPFYDDL
  .| .. |..| |  |      ....
MKQCWHEDPEDRPTFSEI-----HECF
Kinase GL50803_17625.AA Pkinase_Tyr 28-85 28 9.7e-09 30.22 Pfam 1-70 (270) Show / Hide 
Range on Protein: 28-85
Range on HMM: 1-70/270
Sequence Identity: 28% (20 aa)

FTTMRTIGSGSFGVVFIAKTS-----TGELIAIKKVFQDRKYRN-------RELSIMQELGQHPCIIRLI
 | ....|.|.||.|. ..       |.   |.|.. ..   ..       ||..|| .||.|| |.||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLY
Kinase GL50803_17625.AA ERK7 28-86 34 2e-08 24.56 In-house 1-66 (292) Show / Hide 
Range on Protein: 28-86
Range on HMM: 1-66/292
Sequence Identity: 34% (23 aa)

FTTMRTIGSGSFGVVFIA-KTSTGELIAIKKVFQ------DRKYRNRELSIMQELGQHPCIIRLIN
.   . .| | .|.|  |    |.. .|.||.|       |     ||  ..||...|| ||||||
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLIN
Kinase GL50803_17625.AA CDK5 28-85 32 5.7e-08 20.75 In-house 1-64 (287) Show / Hide 
Range on Protein: 28-85
Range on HMM: 1-64/287
Sequence Identity: 32% (21 aa)

FTTMRTIGSGSFGVVFIAKT-STGELIAIKKVFQDRK------YRNRELSIMQELGQHPCIIRLI
.  |  || | .|.|. |.   |.|..|.|.|  |           || ....|| .|. |.||.
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKEL-KHKNIVRLH
Kinase GL50803_17625.AA RCK 28-57 38 2e-06 16.0 In-house 1-31 (298) Show / Hide 
Range on Protein: 28-57
Range on HMM: 1-31/298
Sequence Identity: 38% (12 aa)

FTTMRTIGSGSFGVVFIAK-TSTGELIAIKK
 ......| |..|.|. |. . |||..||||
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKK
Kinase GL50803_17625.AA ERK5 28-58 37 0.000225 11.83 In-house 1-32 (295) Show / Hide 
Range on Protein: 28-58
Range on HMM: 1-32/295
Sequence Identity: 37% (12 aa)

FTTMRTIGSGSFGVVFIA-KTSTGELIAIKKV
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YKIIEKIGNGAYGVVCSARRRKNGQQVAIKKI
Kinase GL50803_17625.AA Pkinase_Tyr 197-224 42 1.140805 2.89 Pfam 182-208 (270) Show / Hide 
Range on Protein: 197-224
Range on HMM: 182-208/270
Sequence Identity: 42% (12 aa)

APELIFGSRYYTTVIDIWSFGCVVAEMI
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APECINYGK-FTTKSDVWSFGVLMWEIF