Gene GL50803_2483 (G.lamblia)

GL50803_2483

Species: G.lamblia
Alias: GK206, GL50803_2483
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Nek
Subfamily: Nek-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_2483.AA Protein None 509 None Fasta, JSON
GL50803_2483.kin_dom Protein Kinase Domain None 256 None Fasta, JSON

Protein domain

Protein domains of GL50803_2483.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase GL50803_2483.AA Pkinase 6-255 31 5.2e-71 247.02 Pfam 1-287 (293) Show / Hide 
Range on Protein: 6-255
Range on HMM: 1-287/293
Sequence Identity: 31% (93 aa)

YRDVTLLGQGAFGSVHRATRVQDNVVVAVKEIDLNRVSAEFHSTFER--EYQIGKSLIHKNILRYLALHQRGDNVLLIEMELCPDG----SLDDMIK-EA
|. .  .|.|.||.| ..... .. .||||.|.. . . ... |  |  | || |.| |.||.|..   ...|.. .. ||.|. |    .| |.|. ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMV-MEYCEGGLYVMDLFDYISTWR

SRGNELVAEDTIWETVVQLCDGLEYLHDNSNKSCGKIIHRDLKPDNIMYS--GAT---LKIGDLGLARM--IEKNSKMTVYVGTPQYMAPEVAR-GLEYD
...     |...   . |.. ||||.|..      .||||||||.||...  | .   .||.| |||.   . .|| ||...||| |||||| | | .|.
HGCFY-FSEWECKFYMYQILRGLEYCHSM------GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYG

TFADIWSVGCIIYEMCCLRRPPWDAK--------------TLEGDPSVDIPEEYS-------------------NDLKELIRNCLRFTPSSRIGLASI
. .|.||.|||.|||.| .|||.. .              ....... |.|...|                    ..|..|..||.. |..|.. . |
PKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI
S_TKc GL50803_2483.AA S_TKc 6-261 31 1.6e-68 234.89 SMART 1-231 (231) Show / Hide 
Range on Protein: 6-261
Range on HMM: 1-231/231
Sequence Identity: 31% (85 aa)

YRDVTLLGQGAFGSVHRATRVQDNVVVAVKEIDLNRVSAEFHSTFEREYQIGKSLIHKNILRYLALHQRGDNVLLIEMELCPD--GSLDDMIKEASR--G
|. . ..|.||||.|.... . .. .||.|.|.          ...|| || |.  |.|| ...   |   . | . ||.|.   |.| |.||.  |  .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

NELVAEDTIWETVVQLCDGLEYLHDNSNKSCGKIIHRDLKPDNIMYSGATLKIGDLGLARMIEKNSKMTVYVGTPQYMAPEVARGLEYDT-FADIWSVGC
.    | ...  . |.|..|||.|.. .     ||||||||.||. .  ..||.| |||| .      | ..||| ||||||     |..  .|.||.||
RFPFPE-HARFYMYQICCALEYCHSH-G-----IIHRDLKPENILLDE-HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

IIYEMCCLRRPPWDAKTLEGDPSVDIPEEYSNDLKELIRNCLRFTPSSRIGLASIST-------NGRV
|.|||.| ..||..    . .   ..    | ..|..||.||.. |. |..   . .          .
ILYEMLC-GYPPFP----QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase GL50803_2483.AA NEK 6-211 33 2.2e-61 210.27 In-house 1-225 (286) Show / Hide 
Range on Protein: 6-211
Range on HMM: 1-225/286
Sequence Identity: 33% (76 aa)

YRDVTLLGQGAFGSVHRATRVQDNVV-----VAVKEIDLNRVSAEFHSTFE-REYQIGKSLIHKNILRYLALHQRGD-NVLLIEMELCP-DGSLDDM---
|. .  .|||.||.|... | .|. .     .. |.|.... | .        | .| |.| | || .|    .  . | | |.|| |   | |...   
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

IKEASRGNELVAEDTIWETVVQLCDGLEYLHDNSNKSCGKIIHRDLKPDNIMYSG-AT----LKIGDLGLARMIEKNSKMT--VYVGTPQYMAPEVARGL
||.    ...  |..||.  .|.| .| |.||..    .||.|||.|| ||. .   .    .||||.|.... .....|    .|||| ||.||| .. 
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRK-GPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNK

EYDTFADIWSVGCIIYEMCCL--RRP
 |.  .||||.||..||||.|  ..|
PYNNKSDIWSLGCVLYEMCTLKPKHP
Kinase GL50803_2483.AA STE 6-249 24 2.5e-58 200.12 In-house 1-345 (359) Show / Hide 
Range on Protein: 6-249
Range on HMM: 1-345/359
Sequence Identity: 24% (87 aa)

YRDVTLLGQGAFGSVHRATRV------QDNVV---------VAVKEIDLNRVSA---------------EFHSTFEREYQIGKSLI--HKNILRYLALHQ
....  .|.||||.|..| ..      . . |         .|.|...|.. ..               | .  ...| .| | .   |.|| .|.  . 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

RG------DNVLLIEMELCPDGSLDDMIKEA-SRGNEL---------VAEDTIWETVVQLCDG-LEYLHDNSNKSCGKIIHRDLKPDNIMYSGATLKIGD
..      |. | | ||... |||||.||.  ..|..|         . |. |   ..|.. | |.|||..       |||||.||.||.      |. |
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH------IIHRDIKPANILL----VKLCD

LGLARMIEKN-----------------SKMTVYVGTPQYMAPEVARG------LEYDTFADIWSVGCIIYEMCCLRRPPW---DAK------TLEG----
 |..  ....                 .| .  |||| .||||| ..       .||| .||||.|| | ||..  .|||            . ..    
FGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATG-KPPWHDMHPMRAMFMIPFNYHMQQ

---------DPSVDIPE-------------------EYSNDLKELIRNCLRFTPSSR
         .|.  .|.                   ..| ..|. |..||.  |. |
QFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKR
Kinase GL50803_2483.AA ULK 6-250 26 3.6e-51 176.32 In-house 1-313 (324) Show / Hide 
Range on Protein: 6-250
Range on HMM: 1-313/324
Sequence Identity: 26% (84 aa)

YRDVTLLGQGAFG-SVHRATRVQD---NVVVAVKEIDLNRVSAEFHS--------TFEREYQIGKSLI---HKN--ILRYLALHQRG--DNVLLIEMELC
|     ||.|.||  |.... ...   |..||.| ||..  .   .          ...| || | |    |.|  | ...   .    .|. .| ||.|
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYII-MEYC

PDGSLDDMIKEASRGNELV------AEDTIWETVVQLCDGLEYLHDNSNKSCGKIIHRDLKPDNIMYSG-------------ATLKIGDLGLARMIEKN-
..| |.. ||.  . .| .       |. . .   |.| |. .||..      .|||||.||.||. .               .|||.| |.|.....| 
NGGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKH------NIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNN

---SKMTVYV------GTPQYMAPEVARGL----EYDTF-ADIWSVGCIIYEMCCLRRPP--WDAKTLEG-----------------DPSVDIP-----E
    ... .|      ||| ||||..  |.    .|... .||||.|||.|||   . |.  | . ...                  .  ...|      
MEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDP

EYSNDLKELIRNCLRFTPSSRI
  |...|.||| .| . .. ||
KISPECKDLIRRMLQYDEKDRI
Kinase GL50803_2483.AA ULK 6-250 25 8.5e-50 171.75 In-house 1-318 (329) Show / Hide 
Range on Protein: 6-250
Range on HMM: 1-318/329
Sequence Identity: 25% (82 aa)

YRDVTLLGQGAFGSVHRATRVQD----NVVVAVKEIDLNRVSAEFHST--------FEREYQIGKSLI----HKN----ILRYLALHQRGD-NVLLIEME
|     ||.|.|| |.... ...    |..||.| ||..  . . .          ...| .| | |     |||    | ...   .  . | . | ||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LCPDGSLDDMIKEASR------GNELVAEDTIWETVVQLCDGLEYLHDNSNKSCGKIIHRDLKPDNIMYSG-------------ATLKIGDLGLARMIEK
.|..| |.. ||.  .       .    |. . .   |.. |. .||..      .|||||.||.||. .               .|||.| |.|.....
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKH------NIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDN

N----SKMTVYV------GTPQYMAPEVARGL----EYDTF-ADIWSVGCIIYEMCCLRRPP--WDAKTLE-----GD-------------PSVDIP---
.      |. .|      ||| ||||..  |.    .|... .||||.|||.|||   . |.  | . ..                        ..|   
DNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDG

--EEYSNDLKELIRNCLRFTPSSRI
     |...|.||| .| . .. ||
NDPQISPECKDLIRRMLQYDEKDRI
Kinase GL50803_2483.AA CAMK 11-250 19 1.3e-48 154.32 In-house 1-414 (425) Show / Hide 
Range on Protein: 11-250
Range on HMM: 1-414/425
Sequence Identity: 19% (83 aa)

LLGQGAFGSVHRATRVQDN------------VVVAVKEIDL----------------NRVSAEFH----------STFEREYQIGKS-------LIHKNI
 ||.|.|| |..... ...            . ||.| ||                  . | . |            ..||..| |.       | |.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LRYLALHQ------------RGDN-------VLLIEM---ELCPDG----SLDDMIKEASRGNEL-----------VAEDTIWETVVQLCDGLEYLHDNS
.. .   .              ..        . . |   |.|. |     | |.|.| ... |            . |.     . |.|....|.|.. 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSH-

NKSCGKIIHRDLKPDNIMYSGA------------------TLKIGDLGLARMIEK------------------------NSKMTVYVGTPQYMA-PEVAR
     .|.||||||.||...                    ..|| | |.|.....                        . ||. ..||| ||| ||| .
-----NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLN

G--------------LEYDTFADIWSVGCIIYEMCCLRRPPWDA---------------------KTLEGDPSVDIPE----------------------
|                |.  .|.||.|.| | | |  .||...                     | ..|. . . |.                      
GKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLC-GYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH

EYSNDLKELIRNCLRFTPSSRI
. | . | |||..|.  |. |.
FVSQECKDLIRKMLQVDPEKRM
Kinase GL50803_2483.AA STE11 6-249 27 4.5e-48 166.04 In-house 1-291 (303) Show / Hide 
Range on Protein: 6-249
Range on HMM: 1-291/303
Sequence Identity: 27% (82 aa)

YRDVTLLGQGAFGSVHRATRVQDNVVVAVKEIDLNRVSA------EFHST------FEREYQIGKSLIHKNILRYLALHQR--GDNVLLIEMELCPDGSL
..   ..|.||||.|...  |  ....|||.| ... .       .. .       .. | .. | | |||| ||.   ..   .. . | || || |||
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSL

DDMIK-EASRGNELVAEDTIWETVVQLCDGLEYLHDNSNKSCGKIIHRDLKPDNIMYSG-AT-LKIGDLGLARMIEKNS----------------KMTVY
 .|..    ...    | .|   . |.. || |||..      .|||||.|..||.     . .|..| | |. ....                 . |.|
SSMLRHKWGPMK--FDEMVIRKYTKQILEGLQYLHSH------GIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPY

---VGTPQYMAPEVARGLE---YDTFADIWSVGCIIYEMCCLRRPPWDAKTL----------EG-DPSVDIPEEYS------NDLKELIRNCLRFTPSSR
   .|||..||||| ..     |.. |||||.||...||..  .|||   .           .| .|   |||. |       .... .|.|. . |. |
NSMMGTPMWMAPEVIKQEGRDGYGRKADIWSLGCTVIEMAT-GKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKR
Kinase GL50803_2483.AA Ciliate-E2 6-251 21 6.3e-46 155.64 In-house 1-354 (365) Show / Hide 
Range on Protein: 6-251
Range on HMM: 1-354/365
Sequence Identity: 21% (77 aa)

YRDVTLLGQGAFGSVHRATRVQDNVV------------------VAVKEIDLNRVSAEFHSTFEREYQIGK----------------SLIHKNILRYLAL
|  . ..|||.|||| .... ...                    |..|.. .....      ...| .| .                .| |.||...   
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

HQR-GDNVLLIEMELCPDGSLDDMIK--EASRGNE---------LVAEDTIWETVV-----------QLCDGLEYLHDNSNKSCGKIIHRDLKPDNIMYS
 |   || . . ||.|  |.| | ||    .|..|           . . ... .            .....||||| .     ..|||||.||.||.. 
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSK-----NNIIHRDIKPENILF-

GATLKIGDLGLARMIEKNSKMTVY--------------------------------VGTPQYMAPEVARGLE---------YDTFADIWSVGCIIYEMCC
   .|| |.||.. . ...... .                                .||| |||||. .| .         ||. .||||.|.|.|||..
---IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

LRRPPWDAKTLEGDPSVD----------------IPEEYSNDLKELIRN----CLRFTPSSRIG
 ..|    . .... . .                .... |.. | ||..    .|   |. ||.
GKPPF-QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT
Kinase GL50803_2483.AA TKL 12-249 19 5.6e-42 145.77 In-house 1-354 (364) Show / Hide 
Range on Protein: 12-249
Range on HMM: 1-354/364
Sequence Identity: 19% (70 aa)

LGQGAFGSVHRATRVQDN--------VVVAVKEIDLNRV----------------------SAEFHSTFEREYQIGKSLI---HKNILRYLALHQRGDNV
.|.|.|| |....  . .         .|||| .  . .                      . | .  ...| .  ....   | ||.....  ..... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------LLIEMELCPDGS-LDDMIKEASRGNELVAEDTIWETVVQLCDGLEYLHDNSNKSCGK--IIHRDLKPDNIMYSGAT------------
            | | ||.|| || |....            . .   . . . |..||| .  |.|.|  |||||||..||.                 
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNA

---LKIGDLGLARMIEKNS--------------------KMTVYVGTPQYMAPEVARGL----------------EYDTFADIWSVGCIIYEMCCLRRPP
   .||.|.||.|......                    .    .|||..||||| ||                 ||.. .|..| | ...|... .|| 
DWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPY

---W--------------DAKTLEG-DPSVD----------IPEEYSNDLKELIRNCLRFTPSSR
   .                  ..|  | ..           ..    ..|.|.  |    |..|
YDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKR
Kinase GL50803_2483.AA STE20 6-205 30 1e-38 134.96 In-house 1-220 (288) Show / Hide 
Range on Protein: 6-205
Range on HMM: 1-220/288
Sequence Identity: 30% (70 aa)

YRDVTLLGQGAFGSVHRATRVQDNVV----VAVKEIDLNRVSA--EFHSTFEREYQIGKSLIHKNILRYLALHQRG---DNVLLIEMELCPDGSLDDMIK
| ..  .|||..|.|..|. .. . .    ||.| ..|.  .   .   . . |..| | . |.|| .|.  ....   |. | | ||.|  ||| |..|
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

EA-SRGNE----LVAEDTIWETVVQLCDGLEYLHDNSNKSCGKIIHRDLKPDNIMYSGA-TLKIGDLGLARMIEK-----NS-KMTVYVGTPQYMAPEVA
.  ..|.        |. |     ... ||.||| |      .|||||.| |||. .     |. | |.. ...|     .. |    |||| .||||| 
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSN------HIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVI

RG-----LEYDTFADIWSVGCIIYEM
..      .||. .||||.|  . ||
QCMEGPDKGYDYKCDIWSLGITAIEM
Kinase GL50803_2483.AA Ciliate-E2-Unclassified 6-211 23 9.9e-38 128.46 In-house 1-269 (352) Show / Hide 
Range on Protein: 6-211
Range on HMM: 1-269/352
Sequence Identity: 23% (66 aa)

YRDVTLLGQGAFGSVHRATRVQDNVVV-----AVKEIDLNRVSAEF-HSTFEREYQIGKS-----------------LIHKNILRYLALHQRG-DNVLLI
|. .  .|||.||.|... . ...  .     . | .. .. . .. .  . .| .. ..                 | |......  ...   .. . |
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

EMELCPDGSLDDMIKEASR----GNE---------LVAEDTIW-----ETVVQLCDGLEYLHDNSNKSCGKIIHRDLKPDNIMYSGA----TLKIGDLGL
 ||.|..|.| ..||. .     ||.          . |  .          |...|||||| . |     |||||.||.||...       .|| |.|.
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNN-----IIHRDIKPENILFDNNGKNYYIKIIDFGI

ARMIEKNSKMTVY-----------------VGTPQYM----APEVARGLEYD--TF--ADIWSVGCIIYEMCCLRRP
.. ...|.. . .                 .|||.||    |||| .| .||  ..  .||||.|.|.|||.  ..|
SKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYP
Kinase GL50803_2483.AA Pkinase_Tyr 12-219 27 4.9e-24 82.03 Pfam 7-222 (270) Show / Hide 
Range on Protein: 12-219
Range on HMM: 7-222/270
Sequence Identity: 27% (63 aa)

LGQGAFGSVHRATRV----QDNVVVAVKEIDLNRVSAE--FHSTFEREYQIGKSL-IHKNILRYLALHQ-RGDN--VLLIEMELCPDGSLDDMIKEA-SR
||.||||.|...|      .... |||| .  .  . |  ..  | || .| |.|  |.||.|...    .|.   .... ||..| |.|.|  ..  . 
LGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIV-MEYMPHGDLLDYLRKHRED

GNELVAEDTIWETVVQLCDGLEYLHDNSNKSCGKIIHRDLKPDNIMYS-GATLKIGDLGLARMIEKNSKMTVYVGT-----PQYMAPEVARGLEYDTFAD
.. |  .| . .  .| ..|.|||...       .|||||   |.. . . . ||.| |||| |.. .   .....        ||||. .  .. |  |
KQPLTMKD-LLQMCWQIAKGMEYLESKN------CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSD

IWSVGCIIYEMCCLRRPP-WDAKTLE
.|| |  ..|.. . . | .   . |
VWSFGVLMWEIFTYGEQPTYPGMSNE
Kinase GL50803_2483.AA TyrKc 6-268 21 2.4e-17 57.61 SMART 1-280 (280) Show / Hide 
Range on Protein: 6-268
Range on HMM: 1-280/280
Sequence Identity: 21% (67 aa)

YRDVTLLGQGAFGSVHRATRVQDNVVVAVKEIDLNRVSAEFHSTFEREYQIGKSL--IHKNILRYLALHQRG------DNVLLIEMELCPDGSLDDMIKE
 .    || |||| |...|     . |||| .  .      .  | || .| ..|   |.||.| ..    .      .  |.| ||..| |.|.| ...
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

ASRGNELVAEDTIWETVVQLCDGLEYLHDNSNKSCGKIIHRDLKPDNIMYSGAT-LKIGDLGLARMIEKN-----SKMTVYV----GTPQ-----YMAPE
  .    .  ..  .  .| ..| ||||..      ..|||||   |....     ||.| ||.| |.       || .  .    |.        ||||
HRPK---LCMKDLLSFCWQIACGMEYLHSK------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPE

VARGLEYDTFADIWSVGCIIYEMCCLRRPPWDA------------KTLEGDPSVDIPEE--------YSNDLKELIRNCLRFTPSSRIGLASISTNGRVH
. .  .. |  |.|| |  ..|.. .  .|.              . ..     ..|..         . .. .... | .. |..|   . |       
CINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-------

RARDRI
  ....
--HECF
Kinase GL50803_2483.AA NEK 226-261 31 1e-06 19.57 In-house 249-286 (286) Show / Hide 
Range on Protein: 226-261
Range on HMM: 249-286/286
Sequence Identity: 31% (12 aa)

IPEE--YSNDLKELIRNCLRFTPSSRIGLASISTNGRV
||.   ||.||..||...|.  |..|    .|  .  .
IPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Ank GL50803_2483.AA Ank 417-443 51 3e-06 26.66 Pfam 1-26 (33) Show / Hide 
Range on Protein: 417-443
Range on HMM: 1-26/33
Sequence Identity: 51% (14 aa)

QGFTALMYAARRGHTQAVSLLLIEAGA
 |||.|..|.|.|||. |..||  .||
DGFTPLHLACRCGHTEVVKMLLQ-HGA
Ank GL50803_2483.AA Ank 387-416 36 0.000146 20.71 Pfam 1-33 (33) Show / Hide 
Range on Protein: 387-416
Range on HMM: 1-33/33
Sequence Identity: 36% (12 aa)

LGTTALMVAAHYNNVEAVKNLLA---EVGARDS
 | |.|..|......| || ||    .| |.| 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank GL50803_2483.AA Ank 447-467 47 0.000122 20.99 Pfam 1-21 (33) Show / Hide 
Range on Protein: 447-467
Range on HMM: 1-21/33
Sequence Identity: 47% (10 aa)

FGHTALMLAAWHGHKDCVKVL
 | |.|.||. .||...|| |
DGFTPLHLACRCGHTEVVKML