Gene GL50803_4191 (G.lamblia)

GL50803_4191

Species: G.lamblia
Alias: GK025, GL50803_4191
External Links: GiardiaDB ,
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_4191.AA Protein None 545 None Fasta, JSON
GL50803_4191.kin_dom Protein Kinase Domain None 513 None Fasta, JSON

Protein domain

Protein domains of GL50803_4191.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc GL50803_4191.AA S_TKc 7-519 11 7.4e-40 139.65 SMART 1-231 (231) Show / Hide 
Range on Protein: 7-519
Range on HMM: 1-231/231
Sequence Identity: 11% (60 aa)

YTDAKELSSGAFSSVFCAVQRNAAGNPVRLVALKRLNKIPENDRNILSNDPHREKMFLEALCHENVVELLDFFESMPYSHSRKGSRFIANSDSEELHCTA
|.  ... .|||..|.... ..      |.||.|...                                                               
YEILRKIGKGAFGKVYKCRHKK----TGRIVAIKIIK---------------------------------------------------------------

TSDGEESSEESFEEENRQELRRALSQAPLADVLECDSQVLASNMYNVSNMSNRTTTESIPRLTDEHDLTEEDLSIVPLSTGATSPHSAQLNSSDTLLGSQ
                                                                                                    
----------------------------------------------------------------------------------------------------

SSVAESIEKQRRSRGPSGSVRSRSSHITSRSGARLTKVYFIVMAYFPY---NLHDLLYCNDVRFHLPQRLPIAIAKNICLQMARGVAYVHSRNIIHRDLK
 ..   |.  ..  .    |.   .  .        . ...|| | .    .|.|..  .  .  |....|   |. .. |......| ||..|||||||
EHIRREIQILKK--HHPNIVKLYDVFQD--------DHLYMVMEYCDGDLGDLFDYIKKRGRHG-LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLK

LLNFLLAADGTVKLGDFGQSCHISEAKLSNSGTRNYRAIELCLGRTDYDY-CVDVYSLGLLFFEVICGRPLFSCSNDIEYVYKTNQLLGPLSPFESVYSA
  | ||    ..|..||| ....     .  ||..|.| |..     |..  .|..|.| ...| .||.|.|.   ... ..|                 
PENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG--------------

PDFDKLVLTSEHEFQSGLLSLLNKYYPEIPEGFYSESFFAAPERSRQLPQLHSNPATIKKPKMVQSMNTIVDGVSSKSARSDGGNKGSLFCNLLCGMLHP
                                                                                       . ........|. 
--------------------------------------------------------------------------------------SPEAKDFIRKCLQK

NIKQRLKMPEVLS-------HPWF
. ..|.   |.|        ||||
DPEKRPTA-EALQDEWDIKCHPWF
Kinase GL50803_4191.AA Pkinase 245-519 18 1.8e-36 130.04 Pfam 75-293 (293) Show / Hide 
Range on Protein: 245-519
Range on HMM: 75-293/293
Sequence Identity: 18% (56 aa)

YFIVMAYFPY-----NLHDLLYCNDVRFHLPQRL--PIAIAKNICLQMARGVAYVHSRNIIHRDLKLLNFLLAADGTV----KLGDFGQSCHI---SEAK
. .|| | .       |.|..       .   ..  .   .|....|..||..| ||..|||||||. |.|.  .|..    |..||| ....   ..  
IYMVMEYCEGGLYVMDLFDYIST-----WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDYNNS-M

LSNSGTRNYRAIELCLGRTDYDYCVDVYSLGLLFFEVICGRPLFSCSN------DIEYVYKTNQLLGPLSPFESVYSAPDFDKLVLTSEHEFQSGLLSLL
 .  ||..|.| |...|...|.. ||..|.|....|..||||.|. .       |  .... .    . ....  .| ..|  .     |          
TTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFP-GHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H----------

NKYYPEIPEGFYSESFFAAPERSRQLPQLHSNPATIKKPKMVQSMNTIVDGVSSKSARSDGGNKGSLFCNLLCGMLHPNIKQRLKMPEVLSHPWF
                                                      . ..    |  . .. .....|... |.|.  ...| ||||
------------------------------------------------------F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase GL50803_4191.AA CMGC 7-392 13 1.4e-33 107.01 In-house 1-372 (513) Show / Hide 
Range on Protein: 7-392
Range on HMM: 1-372/513
Sequence Identity: 13% (69 aa)

YTDAKELSSGAFSSVFCAVQRNAAGN----------PVRLVALKRLNKIPENDRNILSNDPH-----------REKMFLEALC-----------------
|.  | . .|... |. .. ..  ..            ..||.|.. . . ...  .|               || ..|. |                  
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKS---TIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKH

HENVVELLDFFESM---PYSHSRKGSRFIANSDSEELHCTATSDGEESSEESFEEENRQELRRALSQAPLADVLECDSQVLASNMYNVSNMSNRTTTESI
|.|.| |.|.| .    ..  . |..                                                                          
HNNIVKLYDIFYHKNSDGNEYEDKHI--------------------------------------------------------------------------

PRLTDEHDLTEEDLSIVPLSTGATSPHSAQLNSSDTLLGSQSSVAESIEKQRRSRGPSGSVRSRSSHITSRSGARLTKVYFIVMAYFPYNLHDLLYCND-
                                                                   | |       .  ..|. | ...|..... |  
-------------------------------------------------------------------I-S---Q-HFNHLYLVFEYMDHDLYQYIKNNQF

-------VRF-------------HLPQRLPIAIAKNICLQMARGVA--YVHSRN--IIHRDLKLLNFLLAAD--------------------GTVKLGDF
       . .             |. . ..|   . .. |. ||..  | ||..  |||||||  | |.  .                    |..|..||
DYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDF

GQSCHISEA------------------------KLSNSGTRNYRAIELCLGRTDYD---------YCVDVYSLGLLFFEVICG--------RPLFSCSND
| ......                           ..  || ||| |. || ..|.         . .|. |.|  |.| . |        .|||  ...
GLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSE

-----------IEYVYKTNQLLGP
           |.  .|  ..||.
YPNDDKNGKSHIDQLFKIFKVLGT
Kinase GL50803_4191.AA Ciliate-E2-Unclassified 278-519 17 8.7e-27 89.96 In-house 140-352 (352) Show / Hide 
Range on Protein: 278-519
Range on HMM: 140-352/352
Sequence Identity: 17% (51 aa)

AK-----NICLQMARGVAYVHSRN-IIHRDLKLLNFLLAADG---TVKLGDFGQSCHISEA------------------KLSNSGTRNYR----AIELCL
||     ... |   |  | |. | |||||.|. | |.  .|    .|. ||| | .. .                     ...|| ||     | | .|
AKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPE-VL

GRTDYD----YCVDVYSLGLLFFEVICGRPLFSCSNDIEYV--------------YKTNQLLGPLSPFE----SVYSAPDFDKLVLTSEHEFQSGLLSLL
..  ||    |..|..||| ...| . |.. |.. |....               .. |.. .... ..    .                          
QGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQ--------------------------

NKYYPEIPEGFYSESFFAAPERSRQLPQLHSNPATIKKPKMVQSMNTIVDGVSSKSARSDGGNKGSLFCNLLCGMLHPNIKQRLKMPEVLSHPWF
                                 .  . .. .. . .                      .||. ||  |...|. ....| ||||
---------------------------------IPKHWSPEAKDFIN----------------------DLLQKMLKKNPNKRITFEQILNHPWF
Kinase GL50803_4191.AA CDK 246-519 18 1.1e-26 82.25 In-house 94-284 (284) Show / Hide 
Range on Protein: 246-519
Range on HMM: 94-284/284
Sequence Identity: 18% (56 aa)

FIVMAYFPYNLHDLLYCNDVRFHLPQRLPIAIAKNICLQMARGVAYVHSRNIIHRDLKLLNFLLAADGT-----VKLGDFGQSCHISE--------AKLS
..|. | .. |  ..                  |.. .|. ||..| ||..|.|||||  | |.  .|.     .|..||| ..  .          ...
YMVFEYMDHDLKKYMD----------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYT

NSG-TRNYRAIELCLGRTDYD--YCVDVYSLGLLFFEVIC---GRPLFSCSNDIEYVYKTNQLLG--PLSPFESVYSAPDFDKLVLTSEHEFQSGLLSLL
.   |. ||| || || ..|.    .|. |.|  | | ..   ..||| ....|.   |  ...|    .   .| . ||.                   
HEVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-------------------

NKYYPEIPEGFYSESFFAAPERSRQLPQLHSNPATIKKPKMVQSMNTIVDGVSSKSARSDGGNKGSLFCNLLCGMLHPNIKQRLKMPEVLSHPWF
                                                                     .||..||  . |.|..  . |.||.|
---------------------------------------------------------------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase GL50803_4191.AA AGC 271-385 20 7.2e-26 62.5 In-house 141-325 (395) Show / Hide 
Range on Protein: 271-385
Range on HMM: 141-325/395
Sequence Identity: 20% (38 aa)

QRLPIAIAKNICLQ-------MARGVAYVHS-RNIIHRD-LKLLNFLLAADGTVKLGDFGQSCHIS----------------------------------
.|..   |. .. .       .. .. | || ..||||| ||. | || .|| .|| ||| .. .                                   
GRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNP

-------------------EAKLSNSG--TRNYRAIELCLGRTDYDYCVDVYS--LGLLFFEVICGRPLFSCSN---------DIEYVYK
                   .   .  |  | .| | |       |.. .| .|  || |..| ..|.| |.  |         . . ...
NNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQ
Kinase GL50803_4191.AA TKL 256-375 21 7.3e-24 82.82 In-house 126-290 (364) Show / Hide 
Range on Protein: 256-375
Range on HMM: 126-290/364
Sequence Identity: 21% (39 aa)

LHDLLYCNDVRFHLPQRLPIAIAKNICLQMARGVAYVHSRN--------IIHRDLKLLNFLLAADGT--------------VKLGDFGQSCHISE-----
||.|.              .    ...|..|||..| ||.|        |||||||  | |.  ..|              .|..||| |  .|.     
LHYLH--------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMN

-----------------AKLSNSGTRNYRAIELCLGRT---------------DYDYCVDVYSLGLLFFEVICGRPLFS
                 .. .  || .. | |.  | .               .|.  .|||| |....|...... ..
DTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY
Kinase GL50803_4191.AA Ciliate-E2 242-374 22 3.9e-22 72.76 In-house 106-296 (365) Show / Hide 
Range on Protein: 242-374
Range on HMM: 106-296/365
Sequence Identity: 22% (44 aa)

TKVYFIVMAYFPY-NLHDLLYCNDV-RFHLPQ---RLPIAIAKNICLQMAR---------------GVAYVHSRN-IIHRDLKLLNFLLAADGTVKLGDF
.. ...|| |. . .| |... |.  |.| ..   .. .  .|.|  | ..               .. | ||.| |||||.|. | |.     .|. ||
DNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDF

G-------------QSCHISEAKLSNS-----------------------GTRNYRAIELCLG--------RTDYDYCVDVYSLGLLFFEVICGRPLF
|             . . ... ..  .                       || .| | |   |        ...||| .|..||| ...| ..|.| |
GLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF
Kinase GL50803_4191.AA CDK-Unclassified 279-381 32 2.2e-21 67.0 In-house 124-246 (324) Show / Hide 
Range on Protein: 279-381
Range on HMM: 124-246/324
Sequence Identity: 32% (40 aa)

KNICLQMARGVAYVHSRNIIHRDLKLLNFLLAADG-----TVKLGDFGQSCHIS----------EAK-----LSNSGTRNYRAIELCLGRTDYDYCVDVY
.|  .||  | || |.  |.|||.|  | ..   .      .|..||||.|              |.      ..  || ||| || .|   ||. ||. 
RNFMHQMLEGIAYLHCNKIMHRDIKPQNIMITNNNSTVSPMLKIADFGQACFYMNCPPNLNYQTPADPMQQYSTQVSTRWYRAPELLFGSKCYDTGVDIW

SLGLLFFEVICGRPLFSCSNDIE
|.|  . | . | |.|.  ..||
SFGCIYAEWFQGKPIFQGRTEIE
Kinase GL50803_4191.AA STE 7-375 13 1.1e-20 69.92 In-house 1-269 (359) Show / Hide 
Range on Protein: 7-375
Range on HMM: 1-269/359
Sequence Identity: 13% (58 aa)

YTDAKELSSGAFSSVFCAVQRN-----AAGNP------VRLVALKRLNKIPE------------NDRNILSNDPHREKM-FLEALC--HENVVELLDFFE
... ... .||| .|..|. ..       |.       ....| |..|. ..            ...|.   .   . . ..  .   |.|.|. .. ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

SMPYSHSRKGSRFIANSDSEELHCTATSDGEESSEESFEEENRQELRRALSQAPLADVLECDSQVLASNMYNVSNMSNRTTTESIPRLTDEHDLTEEDLS
                                                                                                    
KEGHN-----------------------------------------------------------------------------------------------

IVPLSTGATSPHSAQLNSSDTLLGSQSSVAESIEKQRRSRGPSGSVRSRSSHITSRSGARLTKV---YFIVMAYFP-YNLHDLLY-CNDVRFHLP-----
                                                             .|     .|.| | .   | |..  .  . . |.     
-------------------------------------------------------------HKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQH

-QRLPIAIAKNICLQMARG-VAYVHSRNIIHRDLKLLNFLLAADGTVKLGDFGQSCHISE-----------------A-KL-SNSGTRNYRAIELCLG--
 .|.|  . . || |  .|  .| || .|||||.|  | ||     ||| ||| .  ...                 . |  .  ||  . | |  ..  
QHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNG

---RTDYDYCVDVYSLGLLFFEVICGRPLFS
   . .||. .|..|||..  | ..|.| ..
QGRDKGYDTKCDIWSLGCTIIEMATGKPPWH
Kinase GL50803_4191.AA CAMK 272-372 21 2.4e-20 61.62 In-house 175-332 (425) Show / Hide 
Range on Protein: 272-372
Range on HMM: 175-332/425
Sequence Identity: 21% (34 aa)

RLPIAIAKNICLQMARGVAYVHSRNIIHRDLKLLNFLLAAD-----------------GTVKLGDFGQSCHISEAKLSN---------------------
|.. . |. .  |.. .|.| ||.||.|||||. | ||  .                 ...|. ||| .... . . ..                     
RFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQ

-----SGTRNYRA-IELCLG-------------RTDYDYCVDVYSLGLLFFEVICGRP
      ||  | |  |. .|             .. |.. .|. |.| . .   ||.|
KMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYP
Kinase GL50803_4191.AA CAMKL 245-361 31 4.3e-17 50.96 In-house 96-223 (297) Show / Hide 
Range on Protein: 245-361
Range on HMM: 96-223/297
Sequence Identity: 31% (41 aa)

YFIVMAYFPYN---LHDLLY-CNDVRFHLPQRLPIAIAKNICLQMARGVAYVHSRNIIHRDLKLLNFLLAADG--TVKLGDFGQSCHIS------EAKLS
...|| | .     |.| .    ..|    .|.|   |. .  |.  .|.| ||..|.|||.|. | ||  .|  ..|. ||| | ..       . ||.
IYLVMEYCSGGEMDLFDYIVKHGHRR----GRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLK

NS-GTRNYRAIELCLG-RTDYD-YCVDVYSLG
 . |. .| | |...|  ..|| . ||. |.|
TFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCG
Kinase GL50803_4191.AA AGC 494-519 25 6.2e-09 17.71 In-house 360-395 (395) Show / Hide 
Range on Protein: 494-519
Range on HMM: 360-395/395
Sequence Identity: 25% (9 aa)

NLLCGMLHPNIKQRLK----------MPEVLSHPWF
.|. ..|... ..||             |. .||||
DLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase GL50803_4191.AA TyrKc 7-416 13 1.5e-08 -84.43 SMART 1-280 (280) Show / Hide 
Range on Protein: 7-416
Range on HMM: 1-280/280
Sequence Identity: 13% (66 aa)

YTDAKELSSGAFSSVFCAVQRNAAGNPVRLVALKRLNKIPENDRNILSNDPHREKMFLEAL--CHENVVELLDFFES--------------MPYSHSRKG
 |  |.| .|||  |. .. .       . || | |..           | .||   .  |   |.|.| |.    .              | |      
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDL

SRFIANSDSEELHCTATSDGEESSEESFEEENRQELRRALSQAPLADVLECDSQVLASNMYNVSNMSNRTTTESIPRLTDEHDLTEEDLSIVPLSTGATS
  .. ..  .                                                                                          
KDYLRKHRPK------------------------------------------------------------------------------------------

PHSAQLNSSDTLLGSQSSVAESIEKQRRSRGPSGSVRSRSSHITSRSGARLTKVYFIVMAYFPYNLHDLLYCNDVRFHLPQRLPIAIAKNICLQMARGVA
                                                                                  |. .   ..|.| |.| .
----------------------------------------------------------------------------------LCMKDLLSFCWQIACGME

YVHSRNIIHRDLKLLNFLLAADGTVKLGDFGQSCHISEA-------KLSNS----GTR-----NYRAIELCLGRTD-YDYCVDVYSLGLLFFEVI--CGR
| ||.|.|||||   | |.....||| .||| |  | .        .   .    |..        |.| |. ..  .    ||.| | . .|.   .. 
YLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPE-CI-NYGKFTTKSDVWSFGVCMWEIFTYGQQ

PLFS-----CSND--IEYVYKTNQLLGPLS--------PFESVYSA------------PDFDKLVLTSEHEF
|        .||.  |||| . . .  | .          . .|.             | |  .     ..|
PYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI----HECF
Kinase GL50803_4191.AA CAMK 494-519 30 3e-08 21.94 In-house 400-425 (425) Show / Hide 
Range on Protein: 494-519
Range on HMM: 400-425/425
Sequence Identity: 30% (8 aa)

NLLCGMLHPNIKQRLKMPEVLSHPWF
.|...|| .. ..|..  ..|.|||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase GL50803_4191.AA CAMKL 494-519 30 3.4e-08 22.1 In-house 272-297 (297) Show / Hide 
Range on Protein: 494-519
Range on HMM: 272-297/297
Sequence Identity: 30% (8 aa)

NLLCGMLHPNIKQRLKMPEVLSHPWF
.|. .|| .| ..| .. ....|||.
DLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase GL50803_4191.AA Pkinase_Tyr 280-321 45 1.3e-07 26.35 Pfam 115-156 (270) Show / Hide 
Range on Protein: 280-321
Range on HMM: 115-156/270
Sequence Identity: 45% (19 aa)

NICLQMARGVAYVHSRNIIHRDLKLLNFLLAADGTVKLGDFG
..|.| |.| .| .|.|.|||||   | |.. ...|| .|||
QMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase GL50803_4191.AA Ciliate-E2 498-519 36 1e-06 18.51 In-house 341-365 (365) Show / Hide 
Range on Protein: 498-519
Range on HMM: 341-365/365
Sequence Identity: 36% (9 aa)

G--MLHPNIKQRLK-MPEVLSHPWF
|  ||  . ..|.  . ..| ||||
GKRMLQKDPEKRITGWEQILNHPWF
Kinase GL50803_4191.AA CAMK 12-81 16 1.8e-05 12.84 In-house 1-109 (425) Show / Hide 
Range on Protein: 12-81
Range on HMM: 1-109/425
Sequence Identity: 16% (19 aa)

ELSSGAFSSVFCAVQRNAAGNPV--------RLVALKRLNK-----------------------------IPENDRNILSNDPHREKMFLEA-------L
.| .|.|. |. ....|  |.          . || | ..|                              |.. .|..     ||   .         |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVR-----REIEIMKKLQGIGNKL

CHENVVELLDFFES
 |.|.. |....|.
DHPNIIKLYEVYED
Kinase GL50803_4191.AA CMGC 490-519 30 3.7e-05 11.9 In-house 484-513 (513) Show / Hide 
Range on Protein: 490-519
Range on HMM: 484-513/513
Sequence Identity: 30% (9 aa)

SLFCNLLCGMLHPNIKQRLKMPEVLSHPWF
... .||..||. . ..|..  . |.||.|
PQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase GL50803_4191.AA Pkinase 7-81 25 0.000163 17.04 Pfam 1-71 (293) Show / Hide 
Range on Protein: 7-81
Range on HMM: 1-71/293
Sequence Identity: 25% (20 aa)

YTDAKELSSGAFSSVFCAVQRNAAGNPVRLVALKRLNKIPENDRNI-----LSNDPHREKMFLEALCHENVVELLDFFES
|.  . . ||.|..|. .. ..       .||.|...|  |..        |     .|   .  |.|.|.|.|.|.||.
YHIGRKIGSGSFGCVYKCHHKGTGK----IVAVKIIKKRHEKSWKDQTHRRL-----SEIQIMKRLNHPNIVRLYDWFED
Kinase GL50803_4191.AA Ciliate-E2 7-80 20 0.000178 11.26 In-house 1-102 (365) Show / Hide 
Range on Protein: 7-80
Range on HMM: 1-102/365
Sequence Identity: 20% (21 aa)

YTDAKELSSGAFSSVFCA----VQRNAA---------------GNPVRLVALKRLNKIP----ENDRNILSNDPH-----REKMFLEALCHENVVELLDF
|   | . .|.|.||. .    ||.. |               .. . ..|.|...|      ..  .|.    .      ||  || | | |.... ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE
|.
FQ
Kinase GL50803_4191.AA CDK-Unclassified 494-519 38 0.000878 8.17 In-house 299-324 (324) Show / Hide 
Range on Protein: 494-519
Range on HMM: 299-324/324
Sequence Identity: 38% (10 aa)

NLLCGMLHPNIKQRLKMPEVLSHPWF
|.. .|.. . . |.|  |.|.||||
NCEFQMVMYQPYNRWKCMEILQHPWF
Kinase GL50803_4191.AA TKL 13-76 16 0.005249 6.68 In-house 1-91 (364) Show / Hide 
Range on Protein: 13-76
Range on HMM: 1-91/364
Sequence Identity: 16% (15 aa)

LSSGAFSSVFCAVQRNAAGNPV-----RLVALKRLNKIPENDRNILSNDP--------------------HREKMFLEA---LCHENVVELL
. ||.|. |. .. |.  |        . || |....  .. ... |..                      .|.  .     |.|.|.| ..
IGSGGFGEVYKGKWRGWGG-KCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFM
Kinase GL50803_4191.AA STE 492-519 20 0.022388 4.35 In-house 330-359 (359) Show / Hide 
Range on Protein: 492-519
Range on HMM: 330-359/359
Sequence Identity: 20% (6 aa)

FCNLLCGMLHPNIKQRLKMPEVLS--HPWF
|.. .   |  . ..| .  . |.  ||..
FKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase GL50803_4191.AA Ciliate-E2-Unclassified 7-81 13 0.095663 1.86 In-house 1-92 (352) Show / Hide 
Range on Protein: 7-81
Range on HMM: 1-92/352
Sequence Identity: 13% (13 aa)

YTDAKELSSGAFSSVFCAVQRNAAGNPVRLVALKRLNKIPENDRNILSNDPHREKMFLEALC----------------------HENVVELLDFFES
|.  | . .|.|..|. .....   .   . |.| ..|| ......  |   .... .....                      |...| ... |..
YKIIKQIGQGGFGKVYKCQHKK---QK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQD