Gene GL50803_4405 (G.lamblia)

GL50803_4405

Species: G.lamblia
Alias: GL50803_4405, GK068
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: TTK

Sequence

Name Sequence Type Origin Length Description Download
GL50803_4405.AA Protein None 684 None Fasta, JSON
GL50803_4405.kin_dom Protein Kinase Domain None 296 None Fasta, JSON

Protein domain

Protein domains of GL50803_4405.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc GL50803_4405.AA S_TKc 374-669 23 8.3e-53 182.67 SMART 1-231 (231) Show / Hide 
Range on Protein: 374-669
Range on HMM: 1-231/231
Sequence Identity: 23% (71 aa)

HLVIEQIGAGGYGHVYKALQPS-GKLCAIKLLWSQKGNNYNEKEEKTNYKAMIDEIEIMKRLKGKGICLDLVDCQVVTKHNPFLRRYALIVMELGDT---
  ....|| |..| |||.   . |...||| .                 . .. ||.|.|.  .      | |. .          .  .|||. |.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------------EHIRREIQILKK--HHPNIVKLYDVFQD--------DHLYMVMEYCDGDLG

DLRSFMKEFKSVKRDRVVGPLHPCNLLPESKILSLLYDMITVLHRMHMQGYIHCDLKPQNFMFYKGRLRLIDFGISKAMQQDTTCAVTDTIAGTPKYMAP
||....|. .. ..         .  .||  . ...| ..  |  .| .| ||.||||.| .. . .. ..|||... .         .|. ||| ||||
DLFDYIKKRGRHGL---------RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL---------TTFCGTPWYMAP

EIMLTIGRTMDNKKTELHR-VADVWSIGCILFEMAAGYHPLDRYVDNHPLALLNTVAEKRYVIEADDLHVSPELRELILLCLEHSPKDRITMEGIFA---
|..               .  .|.||.||||.||..|| | .     .. .... .              |||....|  ||.  |..|.|   ...   
EVL------------GYGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEW

----HACL
    |  .
DIKCHPWF
Pkinase GL50803_4405.AA Pkinase 374-666 22 1e-32 116.79 Pfam 1-290 (293) Show / Hide 
Range on Protein: 374-666
Range on HMM: 1-290/293
Sequence Identity: 22% (75 aa)

HLVIEQIGAGGYGHVYKALQPSG-KLCAIKLLWSQKGNNYNEKEEKTNYKAMIDEIEIMKRLKGKGICLDLVDCQVVTKHNPFLRRYALIVMELGDT---
  ....||.|..| |||.   .  |. |.| .. . ... ........      ||.|||||. . | . | |.          ...  .|||. .    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRL----SEIQIMKRLNHPNI-VRLYDWFED-------KDHIYMVMEYCEGGLY

--DLRSFMKEFKSVKRDRVVGPLHPCNLL--PESKILSLLYDMITVLHRMHMQGYIHCDLKPQNFMFY-KGRL----RLIDFGISKAMQQDTTCAVTDTI
  || ....              .  . .  .|  . . .| ..  |  .| .| ||.||||.|...  .| .    ...|||..| ..       ..|.
VMDLFDYIST-------------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTF

AGTPKYMAPEIMLTIGRTMDNKKTELHRVADVWSIGCILFEMAAGYHPLD------RYVDNHPLALLNTVAEKRYVIEADDL----------------HV
.||| |||||. .        . ..  . .|.||.||||.||. |. | .      . .|   .  ..  .. .. .. ..                  .
CGTPWYMAPEVIR--------GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNW

SPELRELILLCLEHSPKDRITMEGIFAH
|.|....|  ||.  ||.|.| | |. |
SEECKDFIKWCLCKDPKKRPTAEQILQH
Kinase GL50803_4405.AA ULK 494-669 25 1.2e-31 109.56 In-house 121-324 (324) Show / Hide 
Range on Protein: 494-669
Range on HMM: 121-324/324
Sequence Identity: 25% (53 aa)

NLLPESKILSLLYDMITVLHRMHMQGYIHCDLKPQNFMFYKG-------------RLRLIDFGISKAMQQD-TTCAVTDTIA------GTPKYMAPEIML
. |.|..... ... .  .  .| ...||.|.|||| .  .|             .| . ||| .|  . .     .. |.       ||| ||||.|  
KRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQ

TIGRTMDNK--KTELH-RVADVWSIGCILFEMAAGYHP----LDRYVDNHPLALLN-----TVAEKRYVIEADD----LHVSPELRELILLCLEHSPKDR
       ..  . . .   .|.||.|||..||  |. |       ....    |.|      . .|   |. ..     ..|||...||  .|.  .|||
-------GQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDR

ITMEGIFAHACL
|. | ||.| ..
ISWEEIFNHPWF
Kinase GL50803_4405.AA ULK 494-669 24 2.5e-31 106.67 In-house 125-329 (329) Show / Hide 
Range on Protein: 494-669
Range on HMM: 125-329/329
Sequence Identity: 24% (52 aa)

NLLPESKILSLLYDMITVLHRMHMQGYIHCDLKPQNFMFYKG-------------RLRLIDFGISKAMQQD-TTCAVTDTIA------GTPKYMAPEIML
. |.|..... ... .  .  .| ...||.|.|||| .  .|             .| . ||| .| .. |    ... |        ||| ||||.|  
KRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQ

TIGRTMDNK--KTELH-RVADVWSIGCILFEMAAGYHP----LDRYVDNHPLALLNTVAEKR-----YVIEAD----DLHVSPELRELILLCLEHSPKDR
       ..  . . .   .|.||.|||..||  |. |       .....   |.|   . .       .. .    | ..|||...||  .|.  .|||
-------GQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDR

ITMEGIFAHACL
|. | .|.| ..
ISWEELFNHPWF
Kinase GL50803_4405.AA STE 375-669 21 7.4e-29 99.09 In-house 1-359 (359) Show / Hide 
Range on Protein: 375-669
Range on HMM: 1-359/359
Sequence Identity: 21% (81 aa)

LVI-EQIGAGGYGHVYKALQP----------------SGKLCAIKLLWSQKGNNYNEK-------EEK--TNYKAMIDEIEIMKRLKGKGICLDLVDC-Q
. . |.|| |..| ||||.                  .|...||| .  .. ||.. .       | |  .. .  . ||.|||...        . .  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNH-------M-HPN

VVTKHNPFLRR--------YALIVMELGD-TDLRSFMKEFKSVKRD-----RVVGPLHPCNLLPESKILSLLYDMITV-LHRMHMQGYIHCDLKPQNFMF
.|. .  ...         .  |.||. |   |....|. ......     .     |    .||| |   ... .   |.  | ...|| |.||.| ..
IVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQ-----H-QHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL

YKGRLRLIDFGISKAMQQD--------------TTCAVTDTIAGTPKYMAPEIMLTIGRTMDNKKTELHRVADVWSIGCILFEMAAGYHPLDRYVDNHPL
      |.|||... ....              |.   ..|..||| .||||...  |..    . .  . .|.||.|| . ||| | .|   . | ||.
----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-R--DKGYDTKCDIWSLGCTIIEMATGKPP---WHDMHPM

-ALLNTVAE--------------KRYVIEADD-----------------LHVSPELRELILLCLEHSPKDRITMEGIFA--HACL
 |....  .              .      |.                  ..|||... | .||.  |..| | .      |  .
RAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase GL50803_4405.AA TTK 427-605 32 1e-26 85.3 In-house 48-218 (344) Show / Hide 
Range on Protein: 427-605
Range on HMM: 48-218/344
Sequence Identity: 32% (61 aa)

EIEIMKRLKGKG-ICLDLVDCQVVTKHNPFLRRYALIVMELGDTDLRSFMKEFKSVKRDRVVGPLHPCNLLPESKILSLLYDMITVLHRMHMQGYIHCDL
|||  ..|..       | | ...   .     | . ||| || || .. .  |            | || | . . . .. |    |  |  | .| ||
EIEMLNKLQQQKDCIIQLYDYEMTMEEQ-----YIYMVMECGDCDLNKWLQKYKT-----------PMNLNPWF-MWCYWQQMLQCVHVIHQHGIVHSDL

KPQNFMFYKGRLRLIDFGISKAMQQ-DTTCAVTDTIAGTPKYMAPEIMLTIGRTMDNKKT-E------LHRVADVWSIGCILFEMAAG
|| || . .|.| |||||| .|.|  |||  | .. .||. ||.|| .     .  |..  .      .   .||||.||||. |  |
KPANFVMVQGMLKLIDFGIANAIQNDDTTNIVKESQIGTFNYMSPEAIQDMSYGNENMCMHHKKPRLKINCKSDVWSLGCILYSMVYG
Kinase GL50803_4405.AA Ciliate-E2 515-669 23 1e-26 88.76 In-house 176-365 (365) Show / Hide 
Range on Protein: 515-669
Range on HMM: 176-365/365
Sequence Identity: 23% (48 aa)

MHMQG-YIHCDLKPQNFMFYKGRLRLIDFGISK-------------AMQQDTTCA-----------------VTDTIAGTPKYMAPEIMLTIGRTMDNKK
.| ..  || |.||.| .|    . .||||.||              ..  .                    ...||.||| ||||||    . . ..|.
LHSKNNIIHRDIKPENILF----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQ

TELHRVADVWSIGCILFEMAAGYHPLDRYVDNHPLALLNTVAEKRYVIEA-------------DDLHVSPELRELILL----CLEHSPKDRIT-MEGIFA
..    .|.||.|.||.||  |..|             .   . ..  .              . ...|.|   ||      .|.  |. ||| .| |. 
KGYDYKCDIWSLGVILYEMLFGKPPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN

HACL
|  .
HPWF
Kinase GL50803_4405.AA CAMK 515-669 20 5.6e-26 80.09 In-house 195-425 (425) Show / Hide 
Range on Protein: 515-669
Range on HMM: 195-425/425
Sequence Identity: 20% (48 aa)

MHMQGYIHCDLKPQNFMF-YK-----------------GRLRLIDFGISKAMQQDTTCA---------------------VTDTIAGTPKYMA-PEIMLT
.| .. .|.|||| | .. ..                 . . .|||| .. ....  .                         |  ||| ||| ||. . 
CHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNG

-IGRTM----DNKKTELHRVADVWSIGCILFEMAAGYHPLDRYVDN----------HPLALLNTVAEKRYVIEADDLH---------------------V
  .  |    |..|.   . .|.||.|.||. |  || | .   ||          ..  |.  . . .|  . . .                      |
KGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFV

SPELRELILLCLEHSPKDRITMEGIFAHACL
|.| . ||  .|.  |..|.| | . .|  .
SQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase GL50803_4405.AA CMGC 374-609 18 3.4e-24 75.59 In-house 1-342 (513) Show / Hide 
Range on Protein: 374-609
Range on HMM: 1-342/513
Sequence Identity: 18% (64 aa)

HLVIEQIGAGGYGHVYKALQ---------------PSGKLCAIKLLWSQKGNNYNEK---EEKTNYKAMIDEIEIMKRLK---------------GKGI-
  .|..|| | || |||.                  .....||| ..... .   .|   |.    .  ..||.|.|.|.                .   
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

CLDLVDCQVVTKHNPFLRR----------YALIVMELGDTDLRSFMKEFKSVKRD-RVVGPLHPC-------------NLLPESKILSLLYDMITVLH--
.. | |. .  . .. . .          .  .|.|. |.||  ..|. .  ... | ..  .                 ..   |    | ... |.  
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLK

RMHMQG--YIHCDLKPQNFMFYK---------------------GRLRLIDFGISKAMQQD-------------------TTCAVTDTIAGTPKYMAPEI
 .| ..   ||.||||.| .. .                     |||...||| ...  .                     .     .   |  | ||||
YCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEI

MLTI----GRTMDNKKTELH------RVADVWSIGCILFEMAAGY-------HPL
.|      .                    |.||.|||..||  ||       .||
LLGWKHYTNH---------NYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPL
Kinase GL50803_4405.AA Ciliate-E2-Unclassified 374-669 21 6.9e-24 79.75 In-house 1-352 (352) Show / Hide 
Range on Protein: 374-669
Range on HMM: 1-352/352
Sequence Identity: 21% (82 aa)

HLVIEQIGAGGYGHVYKALQPSGKLCAIKLLWSQKGNNYNEKEEKTNYKAMIDEIEIMKRLKGKGICL---DLVD-------CQVVTKHNPFL--RRYAL
  .|.||| ||.| |||. . . |  .  .    | ..|. |  ...   .. |...|...|.  .     .. .       . .. |       . .  
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIY

IVMELG-DTDLRSFMKEFKS---VKRDRVVGPLHPCNL----------LPESKIL-----SLLYDMITVLHRMHMQG-YIHCDLKPQNFMFYKG----RL
||||.  . ||. ..|..|.   .            |.          ..| ...      ...  .  |  .| ..  || |.||.| .| ..    ..
IVMEYCEGGDLWQYIKKRKKQKQK-----------GNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYI

RLIDFGISKAMQQDTTC-------------AVTDTIAGTPKYM----APEIMLTIGRTMDNKKTELHRV--ADVWSIGCILFEMAAGYHPLDRYVDNHPL
..|||||||  ||.  |               ..|..||| ||    |||..       .... .      .|.|| |.||.||  ||.| . . ..   
KIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVL-------QGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQ

-------------ALLNTVAEKRYVIEA-----DDLHVSPELRELIL----LCLEHSPKDRITMEGIFAHACL
              |..   .| . .       .. |.|||  ..|      .|.  |. |||.| |. |  .
QLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase GL50803_4405.AA STE11 516-659 27 1e-18 64.48 In-house 133-293 (303) Show / Hide 
Range on Protein: 516-659
Range on HMM: 133-293/303
Sequence Identity: 27% (46 aa)

HMQGYIHCDLKPQNFMFYK-GR-LRLIDFGISKAMQQDTTCAVT---D-----TIAGTPK--------YMAPEIMLTIGRTMDNKKTE-LHRVADVWSIG
| .| || |.|. | .  . |  ..|.|||..| .....||. .   .     .. |||         .||||.        .. ...   | ||.||.|
HSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPMWMAPEV-------IKQEGRDGYGRKADIWSLG

CILFEMAAGYHPLDRYVDNHPLALLNTVAEK-RYVIE-ADDLH-VS---PELRELILLCLEHSPKDRIT
|. .||| | .|   | .  . | .  ....    ..  ...  .|   .|.|. ...|.|| ||.| |
CTVIEMATGKPPWHNYDH-NHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPT
Kinase GL50803_4405.AA NEK 495-572 34 9.2e-15 48.77 In-house 110-196 (286) Show / Hide 
Range on Protein: 495-572
Range on HMM: 110-196/286
Sequence Identity: 34% (30 aa)

LLPESKILSLLYDMITVLHRMHMQ-----GYIHCDLKPQNFMFYK-GR----LRLIDFGISKAMQQDTTCAVTDTIAGTPKYMAPEIM
...|..|.  .. |.  |. || .       .| |.|||| .  | ..    ... |||||| ....|..| | |  ||| ||.||..
YFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYT-TQVGTPYYMSPEVC
Kinase GL50803_4405.AA TyrKc 374-669 19 3.5e-09 -74.26 SMART 1-280 (280) Show / Hide 
Range on Protein: 374-669
Range on HMM: 1-280/280
Sequence Identity: 19% (62 aa)

HLVIEQIGAGGYGHVYKALQPSGKLCAIKLLWSQKGNNYNEKEEKTNYKAMIDEIEIMKRL--KGKGICLDLVDCQVVTKHNPF-LRRYALIVMELGDT-
   ....| | .| |||.       .|.| | . .             .....|..||..|  . . |   .  |        |      .||||. .  
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN--FMYIEPLMIVMEYMPHG

DLRSFMKEFKSVKRDRVVGPLHPCNLLPESKILSLLYDMITVLHRMHMQGYIHCDLKPQNFMFYKGR-LRLIDFGISKAMQQD-TTCAVTDTIA-----G
||... .. .                |. .. ||  ..        | ...|| ||   | .  ...  .  ||| |..   | .. . .|..      |
DLKDYLRKHRPK--------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKG

TP-----KYMAPEIMLTIGRTMDNKKTELHRVADVWSIGCILFEMAA-GYHPLDR---YVDNHPLALLNTVAEKRYVIEADDL-------HVSPELRELI
.      . |||| .      ...| |.     |||| |  ..|.   |  |           . . .    ...|  .  .        . ..|. ...
GKTMLPIRWMAPECI------NYGKFTTK---SDVWSFGVCMWEIFTYGQQPYPGMIQQ--MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIM

LLCLEHSPKDRITMEGIFAHACL
. | .. |.|| |.. |  | |.
KQCWHEDPEDRPTFSEI--HECF
Kinase GL50803_4405.AA CAMK 379-438 19 3.4e-07 18.49 In-house 1-92 (425) Show / Hide 
Range on Protein: 379-438
Range on HMM: 1-92/425
Sequence Identity: 19% (18 aa)

QIGAGGYGHVYKALQP-SG------------KLCAIKL-------------------LWSQKGNNYNEKEEKTNYKAMIDEIEIMKRLKGKG
..| |..| |... .  ..            . .|||                    .  .|. . .....  . | .  ||||||.|.|.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIG
Kinase GL50803_4405.AA NEK 590-604 53 1.5e-05 15.98 In-house 205-219 (286) Show / Hide 
Range on Protein: 590-604
Range on HMM: 205-219/286
Sequence Identity: 53% (8 aa)

ADVWSIGCILFEMAA
.|.||.||.|.||..
SDIWSLGCVLYEMCT
Kinase GL50803_4405.AA TTK 374-402 40 1.8e-05 13.83 In-house 1-30 (344) Show / Hide 
Range on Protein: 374-402
Range on HMM: 1-30/344
Sequence Identity: 40% (12 aa)

HLVIEQIGAGGYGHVYKALQP-SGKLCAIK
 . |.||| || . |...|   |.|. |.|
YSIIKQIGCGGSSKVFQVLSEDSKKIYALK
Kinase GL50803_4405.AA ULK 374-437 28 8.3e-05 12.82 In-house 1-74 (329) Show / Hide 
Range on Protein: 374-437
Range on HMM: 1-74/329
Sequence Identity: 28% (21 aa)

HLVIEQIGAGGYGHVYKAL-QPS----GKLCAIKLLWSQKGNNYNEKEE-KTNYKAMIDEIEIMKRLK----GK
  .....| | .| |||.  . .    ....|.| . .|| |. |   | .   .  . ||.|||.||    .|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHK
RIO GL50803_4405.AA RIO 347-558 14 0.000935 -103.11 SMART 1-253 (253) Show / Hide 
Range on Protein: 347-558
Range on HMM: 1-253/253
Sequence Identity: 14% (41 aa)

FLEKYMSSLALLFRKIPVQILY--INKKVHLVIE---QIGAGGYGHVYKA----LQPSGKLCAIK-----LLWSQKGNNYNE-----K--EEKTNYKAMI
. |.| .. .. | .. . .||  .|...   |    .|. |  . ||.|    ....|. ||.|     .. . .  .| .     |    ..| . |.
DKEDYATY-EEVFDPRTRMTLYKMVNRGYIEEINNHGCISTGKEANVYHAMGGDFDKNGNECAVKIYRTSTTEFKRMWRYIQGDFRFKHGYHHINWRKMV

D-----EIEIMKRLKGKGICLDLVDCQVVTKHNPFLRRYALIVMELGDT------DLRSFMKEFKS--VKRDRVVGPLHPCNLLPESKILSLLYDMITVL
      | ....|.. .|.         . |  |...|   .|||. ..      .|. ...|..   .|.                    ......   
RLWAEKEFRNLQRMYEAGV--------PCPK--PIAWRRHVLVMEFIGDDGWPAPRLKDVEWEEWEMDFKW-------------------EYYWQIMEYM

HRMHMQG-YIHCDLKPQNFMFY------KGRLRLIDF-----------------------------GISKAM-QQDTTCAVTD
..|   . ..|.||   | ..       .. . .||.                             |...     . .  .|.
RKMYHECHLVHADLSEYNMLYHDLEDENDCKVWIIDWSQSVECDHPMWLEFLERDIWNIINFFRRKGVDCDDIYREIFERITG
Kinase GL50803_4405.AA Ciliate-E2 374-435 29 0.001053 8.57 In-house 1-74 (365) Show / Hide 
Range on Protein: 374-435
Range on HMM: 1-74/365
Sequence Identity: 29% (22 aa)

HLVIEQIGAGGYGHVYKALQ-PSGKLCAIKLLWSQK-----------GNNYNEKEEKTN-YKAMIDEIEIMKRLK
  .|..|| |..| |||. .   .|. |||.   ||           .. |. |  | |  ...  || ||....
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREIN
Kinase GL50803_4405.AA STE11 374-435 32 0.002008 8.58 In-house 1-68 (303) Show / Hide 
Range on Protein: 374-435
Range on HMM: 1-68/303
Sequence Identity: 32% (22 aa)

HLVIEQIGAGGYGHVYKALQPS-GKLCAIKLLWSQKGNNY-NEKEEKTNY----KAMIDEIEIMKRLK
    | || | .| |||..  . |.| |.|    |. |.  .. |.. .     ||  .||..|| |.
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLN
Kinase GL50803_4405.AA NEK 637-669 25 0.002386 8.11 In-house 252-286 (286) Show / Hide 
Range on Protein: 637-669
Range on HMM: 252-286/286
Sequence Identity: 25% (9 aa)

H--VSPELRELILLCLEHSPKDRITMEGIFAHACL
|   |..|..|| ..|  .|..| . . |... ..
HRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase GL50803_4405.AA NEK 374-402 31 0.009036 6.05 In-house 1-35 (286) Show / Hide 
Range on Protein: 374-402
Range on HMM: 1-35/286
Sequence Identity: 31% (11 aa)

HLVIEQIGAGGYGHVYKALQ-PSGKL-----CAIK
  .|..|| | .| |||.     ||      ...|
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWK
Kinase GL50803_4405.AA CMGC 635-669 25 0.033257 2.0 In-house 479-513 (513) Show / Hide 
Range on Protein: 635-669
Range on HMM: 479-513/513
Sequence Identity: 25% (9 aa)

DLHVSPELRELILLCLEHSPKDRITMEGIFAHACL
... .|....|.  .|.  |..||| | . .|  .
RKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase GL50803_4405.AA ULK 374-437 24 0.037729 3.5 In-house 1-73 (324) Show / Hide 
Range on Protein: 374-437
Range on HMM: 1-73/324
Sequence Identity: 24% (18 aa)

HLVIEQIGAGGYG-HVYKAL-QPS---GKLCAIKLLWSQKGNNYNEKEE-KTNYKAMIDEIEIMKRLK---GK
  .....| | .|  |||.  . .   ... |.|    .| |. . . | .   .  . ||.||| ||   ..
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHP