Gene GL50803_8037 (G.lamblia)

GL50803_8037

Species: G.lamblia
Alias: GK020, GL50803_8037
External Links: GiardiaDB ,
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDC2

Sequence

Name Sequence Type Origin Length Description Download
GL50803_8037.AA Protein None 308 None Fasta, JSON
GL50803_8037.kin_dom Protein Kinase Domain None 287 None Fasta, JSON

Protein domain

Protein domains of GL50803_8037.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_8037.AA CDC2 15-301 56 1.8e-188 584.93 In-house 1-301 (301) Show / Hide 
Range on Protein: 15-301
Range on HMM: 1-301/301
Sequence Identity: 56% (174 aa)

YRRITKLGEGTYGEVYKAIDTVTNETVAIKRIRLEHEEEG--VPGTAIREVSLLKELQ-HRNIIELKSVIHHNHRLHLIFEYAENDLKKYMD----KNPD
| .| |.||||||.|||..|. ||. ||.|.||||.|.||  || ||||| |.||||. | ||. |. |||  ..| ..||| . |||||||    ||  
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKH

VSMRVIKSFLYQLINGVNFCHSRRCLHRDLKPQNLLLSVSDASETPVLKIGDFGLARAFGIPIRQFT--HEIITLWYRPPEILLGSRHYSTSVDIWSIAC
..  ..||..||...||.|||.|| .||||||||.|.. . .     .||.|||||||||||||. |  ||..|||||.||||||...|||.||.||| |
MPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGN-----IKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGC

IWAEM---LMKTPLFPGDSEIDQLFKIFEVLGLPDDTTWPGVTALPDWKQSFPKFRGKTLKRVLGA--------LLDDEGLDLLTAMLEMDPVKRISAKN
| |||    .| |||.||||||||||||..|| |.. |||||| |||.|..||... . |....           ||.||.|||  ||  || |||||| 
IFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKE

ALEHPYF
||.||||
ALQHPYF
Kinase GL50803_8037.AA CDK 15-301 48 8.99999999999e-168 541.0 In-house 1-284 (284) Show / Hide 
Range on Protein: 15-301
Range on HMM: 1-284/284
Sequence Identity: 48% (154 aa)

YRRITKLGEGTYGEVYKAIDTVTN-----ETVAIKRIRLEH-----EEEGVPGTAIREVSLLKELQHRNIIELKSVIHHN-----------HRLHLIFEY
| .. |.||||||.||||.|. |.     . ||.|.||.|.     |.||.| |||||.|||||| | ||. |. |.|..           ..| ..|||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

AENDLKKYMDKNPDVSMRVIKSFLYQLINGVNFCHSRRCLHRDLKPQNLLLSVSDASETP-VLKIGDFGLARAFGI------PIRQFTHEIITLWYRPPE
.. |||||||         ||....||..|...|||.. .||||||||.|..     . . .|||.||||||||||      |.| .|||..|||||.||
MDHDLKKYMD---------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVK-CGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPE

ILLGSRHYS--TSVDIWSIACIWAEMLM---KTPLFPGDSEIDQLFKIFEVLGLPDDTTWPGVTALPDWKQSFPKFRGKTLKRVLGALLDDEGLDLLTAM
.||||.|||  |..|.||. || |||..   . ||||||||||||||||...| |.. .||||| |||.                         |||  |
LLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-------------------------DLLNKM

LEMDPVKRISAKNALEHPYF
| .|| |||||. ||.||||
LCYDPKKRISAEQALQHPYF
Kinase GL50803_8037.AA CDK5 15-301 53 2.2e-163 520.49 In-house 1-287 (287) Show / Hide 
Range on Protein: 15-301
Range on HMM: 1-287/287
Sequence Identity: 53% (157 aa)

YRRITKLGEGTYGEVYKAIDTVTNETVAIKRIRLEHEEEGVPGTAIREVSLLKELQHRNIIELKSVIHHNHRLHLIFEYAENDLKKYMDK-NPDVSMRVI
| .. |.|||||| |||| .  | | ||.||.||. | |||| |||||..|||||.|.||. |  ||| . .| |.||.  .|||||||. | ...|..|
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNGEMDMHII

KSFLYQLINGVNFCHSRRCLHRDLKPQNLLLSVSDASETPVLKIGDFGLARAFGIPIRQFTHEIITLWYRPPEILLGSRHYSTSVDIWSIACIWAEML-M
|||.|||  |. |||... |||||||||||      .    || .|||||||||||.| ..||..||||||| .|.||.|||||.|.||. || |||   
KSFMYQLLKGLAFCHEHHVLHRDLKPQNLLI-----NKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANA

KTPLFPGDSEIDQLFKIFEVLGLPDDTTWPGVTALPDWK---QSFPKFRGKT-LKRVLGALLDDEGLDLLTAMLEMDPVKRISAKNALEHPYF
  ||||| .. |||..||...| |   .||..| |||.|   | .|.. ... .. .    || .|.|||  ||...| .|||||.||.||||
GRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPK-LDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase GL50803_8037.AA CMGC 15-301 27 7.50000000001e-144 476.12 In-house 1-513 (513) Show / Hide 
Range on Protein: 15-301
Range on HMM: 1-513/513
Sequence Identity: 27% (141 aa)

YRRITKLGEGTYGEVYKAID--------------TVTNETVAIKRIRLEH---------EEEGVPGTAIREVSLLKELQ-----------------HRNI
|  | |.||||||.|||..|              . ||| ||||.|....         |..|.| .|.||...||.|.                 | ||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

IELKSVIHHNH-----------------RLHLIFEYAENDLKKYMDKNP---------DVSMRV------------IKSFL------YQLINGVN--FCH
. |. ...|..                  |.|.||| ..||..|...|.           |  .            ||.|.      ||...|..  .||
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

SRR--CLHRDLKPQNLLLSVSDAS---------------ETPVLKIGDFGLARAFGIP---------------------IRQFTHEIITLWYRPPEILLG
|..   .||||||.|.|..    .               .  .|||.||||||.....                      |..||.. |.|||.||||||
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

SRHYS---------TSVDIWSIACIWAEMLMK--------TPLFPGDSE-----------IDQLFKIFEVLGLPD---------------DTTWPGVTAL
..||.         |..|.||..|| |||...         |||||.||           ||||||||.||| |.               . .||... |
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL

PDWKQ--------------S------------FPKFRGKTLKRVLGA----------------------------------LLDDEGLDLLTAMLEMDPV
|....              |            ||....|..|..                                     ..|....|||  ||..|| 
PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD

KRISAKNALEHPYF
|||.|. ||.||||
KRITAEQALQHPYF
Kinase GL50803_8037.AA CDK7 15-301 41 4.5e-135 362.32 In-house 1-288 (288) Show / Hide 
Range on Protein: 15-301
Range on HMM: 1-288/288
Sequence Identity: 41% (123 aa)

YRRITKLGEGTYGEVYKAIDTVTNETVAIKRIR-LEHEEE---GVPGTAIREVSLLKELQHRNIIELKSVIHHNHRLHLIFEYAENDLKKYMDKNPDVSM
|  | ..|||... |||| |..|.. ||||.|. | | .|   |.  |||||. .|.|.|| |.|.|  .. |   . |.|.. . ||      .  . .
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDKSIILT

RV-IKSFLYQLINGVNFCHSRRCLHRDLKPQNLLLSVSDASETPVLKIGDFGLARAFGIPIRQFTHEIITLWYRPPEILLGSRHYSTSVDIWSIACIWAE
   ||..  ..  |. .||    ||||||| |||.     .|  .|||.||||||..| | | .|| ..| ||| || | | ||| |.||.||. || ||
PAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLM-----NENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAE

MLMKTPLFPGDSEIDQLFKIFEVLGLPDDTTWPGVTALPDWKQSFPKFRG---KTLKRVLGALLDDEGLDLLTAMLEMDPVKRISAKNALEHPYF
 .  .| .||||.|||| .||. || | . .||......|  . | .| |     |. .  |  ||  |||.  |. |.|.||...  .|..|||
LMLRVPYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYIK-FKDFPGYSRTPLRHIFTAASDDL-LDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase GL50803_8037.AA PFTAIRE 15-301 47 4.3e-122 411.93 In-house 1-287 (287) Show / Hide 
Range on Protein: 15-301
Range on HMM: 1-287/287
Sequence Identity: 47% (139 aa)

YRRITKLGEGTYGEVYKAIDTVTNETVAIKRIRLEHEEEGVPGTAIREVSLLKELQHRNIIELKSVIHHNHRLHLIFEYAENDLKKYMDKNPD-VSMRVI
| .. |||||.|  |||.|  ...  || | |||. .|||.| |||||.||||.|.| ||. |  .||    | ..||| . ||..|||| |    .. .
YEKLEKLGEGSYATVYKGISCINQQFVALKEIRLQ-QEEGTPFTAIREASLLKNLKHANIVCLHDIIHTKETLTFVFEYVHTDLCQYMDKHPGGMHPNNV

KSFLYQLINGVNFCHSRRCLHRDLKPQNLLLSVSDASETPVLKIGDFGLARAFGIPIRQFTHEIITLWYRPPEILLGSRHYSTSVDIWSIACIWAEMLMK
. ||.||. |  .|| || |||||||||||  .|.. |   ||  |||||||  .| . . ||..||||||| .||||  |||..|.| . ||  ||.  
RLFLFQLLRGLSYCHQRRVLHRDLKPQNLL--ISHCGE---LKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMMWG

TPLFPGD-SEIDQLFKIFEVLGLPDDTTWPGVTALPDWKQSFPK---FRGKTLKRVLGALL-DDEGLDLLTAMLEMDPVKRISAKNALEHPYF
 |.|||     ||| |||.||| | . |||||. || .|    .   .. | |....  ..   .. ||.. || . | .|.||..|..||||
QPAFPGMKDITDQLEKIFKVLGTPTEDTWPGVCHLPNYKPHWFRGRFYKPKKLCHQWPRIYYIPHAEDLMMKMLQCEPRDRVSAQEAMQHPYF
Kinase GL50803_8037.AA PCTAIRE 15-301 48 2.8e-118 399.23 In-house 1-291 (291) Show / Hide 
Range on Protein: 15-301
Range on HMM: 1-291/291
Sequence Identity: 48% (144 aa)

YRRITKLGEGTYGEVYKAIDTVTNETVAIKRIRLEHEEEGVPGTAIREVSLLKELQHRNIIELKSVIHHNHRLHLIFEYAENDLKKYMDKNPDV-SMRVI
| .. |||||||  |||     |.  || | ||||| ||| | ||||||||||.|.| ||. |  .|| .| | |.||| . |||.||| .  . .|  .
YIKLDKLGEGTYATVYKCRSKLTDNLVALKEIRLEH-EEGAPCTAIREVSLLKDLKHANIVTLHDIIHTHHQLTLVFEYMDMDLKQYMDDCGNIMNMHNV

KSFLYQLINGVNFCHSRRCLHRDLKPQNLLLSVSDASETPVLKIGDFGLARAFGIPIRQFTHEIITLWYRPPEILLGSRHYSTSVDIWSIACIWAEMLMK
| ||.||  |  .|| |. |||||||||||.      |  .||  |||||||  .| . . ||..|||||||..|.||  |||..|.| . ||..||   
KLFLFQLLRGLAYCHRRKILHRDLKPQNLLI-----NERGELKLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDYSTQIDMWGVGCIFYEMCTG

TPLFPGDS------EIDQLFKIFEVLGLPDDTTWPGVTALPDWKQ-SFPKFRGKTLKRVLGALLD---DEGLDLLTAMLEMDPVKRISAKNALEHPYF
 |||||          |||  || .|| ||. |||||........ .||..| . |  .    ||    .. |||| .|   . .|.|| .|..||||
RPLFPGSTDSHYPGVKDQLHMIFRILGTPDEKTWPGVKSNEEFRTYNFPRYREQPLINH-APRLDKILKQCQDLLTMLLQYESKNRVSAEKAMKHPYF
Kinase GL50803_8037.AA PITSLRE 15-301 42 6.1e-112 378.2 In-house 1-295 (295) Show / Hide 
Range on Protein: 15-301
Range on HMM: 1-295/295
Sequence Identity: 42% (127 aa)

YRRITKLGEGTYGEVYKAIDTVTNETVAIKRIRLE--HEEEGVPGTAIREVS-LLKELQHRNIIELKSVI--HHNHRLHLIFEYAENDLKKYMDKNP---
.  . . .|||||.||.| |. |.| ||.||. .|   | || | |..||.. .|..|||.||. .| ..         ...|| | |||  |..     
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRRN

-DVSMRVIKSFLYQLINGVNFCHSRRCLHRDLKPQNLLLSVSDASETPVLKIGDFGLARAFGIPIRQFTHEIITLWYRPPEILLGSRHYSTSVDIWSIAC
   .   ||... || .|| . |.   .|||||  |||.     |   .|||.|||||| .| ||. .|  ..||||| ||.|||.. ||| ||.||. |
QPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLY-----SHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGC

IWAEMLMKTPLFPGDSEIDQLFKIFEVLGLPDDTTWPGVTALPDWKQ--SFPKFRGKTLKRVLG--ALLDDEGLDLLTAMLEMDPVKRISAKNALEHPYF
| ||.... |||.|.|||||. .||  .| |    |||.| || ||   .||.    .|..  .  ... | |.|||  ||. .| .||.|  || ||.|
IFAEFITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALKHPWF
Kinase GL50803_8037.AA CRK7 15-301 33 3.6e-98 332.44 In-house 1-343 (343) Show / Hide 
Range on Protein: 15-301
Range on HMM: 1-343/343
Sequence Identity: 33% (118 aa)

YRRITKLGEGTYGEVYKAIDTVTNETVAIKRIRLEHE---EEGVPGTAIREVSLLKELQHRNIIELKSVIHH--------NHR--LHLIFEYAENDLKKY
|..|   |||||| |||| .. |.| || |..|...|   .|| | |||||. .|..|.|.||. || ..          .|.    ..|||. .||   
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGL

MDKN--PDVSMRVIKSFLYQLINGVNFCHSRRCLHRDLKPQNLLLSVSDASETPVLKIGDFGLARAFGIPI--RQFTHEIITLWYRPPEILLGSRHY---
..     . |   .|.|. ||  |.. || .  ||||.|  |.|.  .       .|| |||||| .      |..|  .||||||||| |||  .|   
LESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGE-----VKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQ

-----------------------------------STSVDIWSIACIWAEMLMKTPLFPGDSEIDQLFKIFEVLGLPDDTTWPGVTALPDWKQSFPKF--
                                    ...|.||  || .| . |.|.|.|  |..|| ||... | |    || |. || |.   ||   
HILKELIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNTMKPKRQY

RGKTLKRVL----GALLDDEGLDLLTAMLEMDPVKRISAKNALEHPYF
. . .. .       ... | ||||  || .|| ||..|. .|.|..|
NRRLREEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase GL50803_8037.AA Pkinase 15-301 31 2.3e-97 334.54 Pfam 1-293 (293) Show / Hide 
Range on Protein: 15-301
Range on HMM: 1-293/293
Sequence Identity: 31% (95 aa)

YRRITKLGEGTYGEVYKAIDTVTNETVAIKRIRLEHEEEGVPGTAIR--EVSLLKELQHRNIIELKSVIHHNHRLHLIFEYAEN-----DLKKYMD--KN
|... |.|.|..|.|||...  |...||.|.|...||..... |..|  |....|.|.| ||..|. . . . ......||.|.     ||. |.   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

PDV--SMRVIKSFLYQLINGVNFCHSRRCLHRDLKPQNLLLS-VSDASETPVLKIGDFGLARAF-GIPIRQFTHEIITLWYRPPEILLGSRHYSTSVDIW
  .  |....|...||.. |...|||....||||||.|.|..   . ..   .||.|||||. |   . . .|.   |.||..||...|...|...||.|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA--CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SIACIWAEMLMKTPLFPGD----SEIDQLFKIFEVLGLPDDTTWPGVTALPDWKQSFPKFRGKTLKRVLGALLDDEGLDLLTAMLEMDPVKRISAKNALE
|. || .||| . |.|||.    . .||...|....| | .  ||     .. .  |.  . ..  ...  ....|..|... .|..|| ||..|. .|.
SCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF--FRH-W-HF-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQ

HPYF
||.|
HPWF
Kinase GL50803_8037.AA S_TKc 15-301 28 4.9e-96 326.28 SMART 1-231 (231) Show / Hide 
Range on Protein: 15-301
Range on HMM: 1-231/231
Sequence Identity: 28% (87 aa)

YRRITKLGEGTYGEVYKAIDTVTNETVAIKRIRLEHEEEGVPGTAIREVSLLKELQHRNIIELKSVIHHNHRLHLIFEYAEN---DLKKYMDKNPD----
|. . |.|.|..|.|||.... |.. ||||.|.          ...||...||. .| ||. |. |... ..|....||...   ||..|..|..     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--VSMRVIKSFLYQLINGVNFCHSRRCLHRDLKPQNLLLSVSDASETPVLKIGDFGLARAFGIPIRQFTHEIITLWYRPPEILLGSRHYST-SVDIWSIA
   .  ......||.......|||.. .||||||.|.||.        ..||.|||||| .       |. . |.||..||.|    .|.. ..|.||. 
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCG

CIWAEMLMKTPLFPGDSEIDQLFKIFEVLGLPDDTTWPGVTALPDWKQSFPKFRGKTLKRVLGALLDDEGLDLLTAMLEMDPVKRISAKNALE-------
|| .|||   |.||      |....|...|                                    ..|..|..  .|..|| ||..|  ||.       
CILYEMLCGYPPFP------QMQMMFKKIG------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKC

HPYF
||.|
HPWF
Kinase GL50803_8037.AA CDK4 15-301 41 2.3e-95 323.14 In-house 1-290 (290) Show / Hide 
Range on Protein: 15-301
Range on HMM: 1-290/290
Sequence Identity: 41% (125 aa)

YRRITKLGEGTYGEVYKAIDTVTNETVAIKRIRLEHEEE--GVPGTAIREVSLLKELQ---HRNIIELKSVIH--HNHR----LHLIFEYAENDLKKYMD
|  .  .||| || ||.| |. |   || |..|   .||  |.|   |||.|... |.   | ||. |..| |     |    . ..||  . ||. |.|
YQCVAEIGEGAYGTVYRARDLHTGHFVALKQVRIPIGEEGGGMPMSTIREISVMRHLCQFEHPNIVKLMDVCHVMDTDRAEMKITMVFEHCDWDLHTYLD

KNPD--VSMRVIKSFLYQLINGVNFCHSRRCLHRDLKPQNLLLSVSDASETPVLKIGDFGLARAFGIPIRQFTHEIITLWYRPPEILLGSRHYSTSVDIW
| |   ..   ||    ||. || | || |  ||||||||.|.. .       .|. |||||| ..     .|  ..||||| ||.|| |  | | ||.|
KCPPPGMPPCTIKHMMHQLLRGVDFLHSHRIIHRDLKPQNILVTSDGH-----VKLADFGLARIYSFQMA-LTPVVVTLWYRAPEVLLQS-YYNTPVDMW

SIACIWAEMLMKTPLFPGDSEIDQLFKIFEVLGLPDDTTWPGVTALPDWKQSFPKFRGKTLKRVLGALLDDEGLDLLTAMLEMDPVKRISAKNALEHPYF
|..|| |||    |||.| || ||| |||.| |||    ||   .||   ..||  . . .| .    ..  |.|||  ||  .. ||.||  .|.||||
SVGCIFAEMYCRRPLFCGQSEKDQLHKIFDVMGLPPEDDWPRDVSLP--WDHFPQRHPRPFKDFC-PHMCKQGDDLLQKMLCYNHHKRMSAYQCLQHPYF
Kinase GL50803_8037.AA Pkinase_Tyr 15-165 30 2.1e-20 69.73 Pfam 1-160 (270) Show / Hide 
Range on Protein: 15-165
Range on HMM: 1-160/270
Sequence Identity: 30% (52 aa)

YRRITKLGEGTYGEVYKAIDT----VTNETVAIKRIRLEHEEEGVPGTA------IREVSLLKEL-QHRNIIELKSVIH-HNHR--LHLIFEYAEN-DLK
 . . ||||| .|||||.. .     |. .||.| ..     ||    .      .||....|.| .| ||. |  |.  .     . ...||... ||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK-----EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL

KYMDK----NPDVSMRVIKSFLYQLINGVNFCHSRRCLHRDLKPQNLLLSVSDASETPVLKIGDFGLARA
.|  |    .. ..|  . .. .|  .| .. .|..| ||||   | |..     |. | ||.||||||.
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVT-----ENNVVKICDFGLARD
Kinase GL50803_8037.AA TyrKc 15-301 21 1e-14 15.42 SMART 1-280 (280) Show / Hide 
Range on Protein: 15-301
Range on HMM: 1-280/280
Sequence Identity: 21% (69 aa)

YRRITKLGEGTYGEVYKAIDTVTNETVAIKRIRLEHEEEGVPGTAIREVSLLKEL--QHRNIIELKSVIHHN-------HRLHLIFEYAEN-DLKKYMDK
 . . ||||| .|||||.. .   ..||.| .. ..         .|| .....|  .| ||. |  |. .        . | ...||... |||.|  |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

NPD-VSMRVIKSFLYQLINGVNFCHSRRCLHRDLKPQNLLLSVSDASETPVLKIGDFGLARAFGIP-------IRQFT----HEI--ITLWYRPPEILLG
. . ..|.   || .|  .| .. ||..| ||||   | |..        . ||.||||.|. .             .    ..   . .   .|| .  
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-N

SRHYSTSVDIWS--IACIWAEMLMKTPLFPGD--------SEIDQLFKIFEVLGLPDD----TTWPGVTALPDWKQSFPKFRGKTLKRVLGALLDDEGLD
 . ..|  |.||  . |.| |..      . .        .|. .. |  . .  |..                                     ||  .
YGKFTTKSDVWSFGV-CMW-EIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS--------------------------F-VCCPDEMYQ

LLTAMLEMDPVKRISAKNALEHPYF
. .   . || .| . ..   | .|
IMKQCWHEDPEDRPTFSEI--HECF